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Results for MligTC455_06847

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_06847 632 13.17 Mlig455_021833

Neo: -

Age: logFC(26M/2M)=-0.278

Region-enriched R3: 1.828/0.00930

MAST4 Mlig455_021833 {REF} {Length: 5984} {Pfam: Domain of unknown function (DUF1908) [PF08926.13, score=233.5]; Protein kinase domain [PF00069.27, score=197.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=82.4]; ABC1 atypical kinase-like domain [PF03109.18, score=24.3]; PDZ domain [PF17820.3, score=23.4]; Phosphotransferase enzyme family [PF01636.25, score=22.2]; Kinase-like [PF14531.8, score=17.9]} {Human: ENSG00000069020, MAST4, microtubule associated serine/threonine kinase family member 4, [RH, Score=664, Expect=0.0]; ENSG00000086015, MAST2, microtubule associated serine/threonine kinase 2, [RH, Score=664, Expect=0.0]; ENSG00000099308, MAST3, microtubule associated serine/threonine kinase 3, [RH, Score=636, Expect=0.0]} {Mouse: ENSMUSG00000034751, Mast4, microtubule associated serine/threonine kinase family member 4, [RH, Score=663, Expect=0.0]; ENSMUSG00000003810, Mast2, microtubule associated serine/threonine kinase 2, [RH, Score=663, Expect=0.0]} {Dmel: FBgn0267390, dop, drop out, [RH, Score=502, Expect=8e-149]} {Celegans: WBGene00002192, kin-4, KIN-4 protein; Protein KINase, [RH, Score=596, Expect=0.0]} {Smed: dd_Smed_v6_2028_0_1, dd_Smed_v6_2028_0_1, [Score=649, Expect=0.0]} {RNA1509_23083, RNA1509_4612, RNA1509_52145} {RNA1310_726.1, RNA1509_23083, RNA1509_4612, RNA1509_52145} {RNA1509_23083, RNA1509_4612, RNA1509_52145, RNA815_4601}

Cumulative graph for MligTC455_06847

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -7.022 3.871 0.03405 0.46252
RegionR2 1.408 3.871 0.03979 0.23167
RegionR3 1.828 3.871 0.00023 0.00930
RegionR4 1.565 3.871 0.01832 0.09577
RegionR5 0.646 3.871 0.41525 0.77480
RegionR6 1.125 3.871 0.09249 0.55946
RegionR7 0.815 3.871 0.34255 0.97963
RegionR8 -0.365 3.871 0.93708 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 7.435 3.871 0.03971 0.66665
RegenerationR2 -0.481 3.871 0.14151 0.57143
RegenerationR3 -0.796 3.871 0.02847 0.30328
RegenerationR4 -0.156 3.871 0.69437 0.95148
RegenerationR5 0.062 3.871 0.86981 1.00000
RegenerationR6 -0.079 3.871 0.84411 0.99767
RegenerationBL -1.558 3.871 0.03831 0.22191
RegenerationTP 0.346 3.871 0.55330 0.93549


Genes with expression patterns similar to MligTC455_06847

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_06847 632 13.17 Mlig455_021833

Neo: -

Age: logFC(26M/2M)=-0.278

Region-enriched R3: 1.828/0.00930

MAST4 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_021833 {REF} {Length: 5984} {Pfam: Domain of unknown function (DUF1908) [PF08926.13, score=233.5]; Protein kinase domain [PF00069.27, score=197.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=82.4]; ABC1 atypical kinase-like domain [PF03109.18, score=24.3]; PDZ domain [PF17820.3, score=23.4]; Phosphotransferase enzyme family [PF01636.25, score=22.2]; Kinase-like [PF14531.8, score=17.9]} {Human: ENSG00000069020, MAST4, microtubule associated serine/threonine kinase family member 4, [RH, Score=664, Expect=0.0]; ENSG00000086015, MAST2, microtubule associated serine/threonine kinase 2, [RH, Score=664, Expect=0.0]; ENSG00000099308, MAST3, microtubule associated serine/threonine kinase 3, [RH, Score=636, Expect=0.0]} {Mouse: ENSMUSG00000034751, Mast4, microtubule associated serine/threonine kinase family member 4, [RH, Score=663, Expect=0.0]; ENSMUSG00000003810, Mast2, microtubule associated serine/threonine kinase 2, [RH, Score=663, Expect=0.0]} {Dmel: FBgn0267390, dop, drop out, [RH, Score=502, Expect=8e-149]} {Celegans: WBGene00002192, kin-4, KIN-4 protein; Protein KINase, [RH, Score=596, Expect=0.0]} {Smed: dd_Smed_v6_2028_0_1, dd_Smed_v6_2028_0_1, [Score=649, Expect=0.0]} {RNA1509_23083, RNA1509_4612, RNA1509_52145} {RNA1310_726.1, RNA1509_23083, RNA1509_4612, RNA1509_52145} {RNA1509_23083, RNA1509_4612, RNA1509_52145, RNA815_4601}
2. MligTC455_50724 402 8.37 Mlig455_007823

Neo: -

Age: -

Region-enriched R5: 1.057/0.03844

NRBP1 3.487 - - 0.873 0.957 0.728 0.929 Mlig455_007823 {REF} {Length: 5624} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=66.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=37.5]} {Human: ENSG00000115216, NRBP1, nuclear receptor binding protein 1, [RH, Score=188, Expect=4e-50]} {Mouse: ENSMUSG00000029148, Nrbp1, nuclear receptor binding protein 1, [RH, Score=184, Expect=6e-49]} {Dmel: FBgn0027497, Madm, MLF1-adaptor molecule, [RH, Score=153, Expect=4e-38]} {Celegans: WBGene00010427, hpo-11, [RH, Score=169, Expect=1e-43]} {Smed: dd_Smed_v6_5859_0_1, dd_Smed_v6_5859_0_1, [RH, Score=199, Expect=3e-52]} {RNA1509_18578, RNA1509_19619, RNA1509_33489} {RNA1310_6856, RNA1509_18578, RNA1509_19619, RNA1509_33489} {RNA1509_18578, RNA1509_19619, RNA1509_33489, RNA815_11040}
3. MligTC455_47459 866 18.03 Mlig455_020310

Neo: -

Age: -

RALGPS1 2.602 - 0.744 - 0.908 - 0.950 Mlig455_020310 {REF} {Length: 4259} {TRANSSPLICED} {Pfam: RasGEF domain [PF00617.21, score=166.7]} {Human: ENSG00000136828, RALGPS1, Ral GEF with PH domain and SH3 binding motif 1, [RH, Score=278, Expect=2e-83]; ENSG00000116191, RALGPS2, Ral GEF with PH domain and SH3 binding motif 2, [RH, Score=271, Expect=2e-80]} {Mouse: ENSMUSG00000038831, Ralgps1, Ral GEF with PH domain and SH3 binding motif 1, [RH, Score=276, Expect=2e-82]; ENSMUSG00000026594, Ralgps2, Ral GEF with PH domain and SH3 binding motif 2, [RH, Score=271, Expect=7e-82]} {Dmel: FBgn0034158, CG5522, [RH, Score=281, Expect=5e-83]} {Celegans: WBGene00009100, rgef-1, Rap Guanine nucleotide Exchange Factor homolog, [Score=74.3, Expect=2e-13]} {Smed: dd_Smed_v6_9244_0_1, dd_Smed_v6_9244_0_1, [RH, Score=218, Expect=5e-59]} {RNA1509_3628} {RNA1310_3714.1} {RNA815_2665}
4. MligTC455_14891 278 5.78 Mlig455_024432

Neo: -

Age: -

2.523 - - 0.741 0.957 - 0.825 Mlig455_024432 {REF} {Length: 2023} {RNA1509_4122} {RNA1310_50028} {RNA815_18644}
5. MligTC455_46795 785 16.35 Mlig455_000535

Neo: -

Age: logFC(26M/2M)=-0.364

Region-enriched R2: 1.672/0.01916

HTR1B 2.482 0.702 0.830 - 0.950 - - Mlig455_000535 {REF} {Length: 4573} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=255.2]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=53.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.4]; Family of unknown function (DUF5684) [PF18936.2, score=19.6]} {Human: ENSG00000135312, HTR1B, 5-hydroxytryptamine receptor 1B, [RH, Score=243, Expect=3e-75]} {Mouse: ENSMUSG00000021721, Htr1a, 5-hydroxytryptamine (serotonin) receptor 1A, [Score=251, Expect=3e-78]} {Dmel: FBgn0004573, 5-HT7, 5-hydroxytryptamine (serotonin) receptor 7, [RH, Score=276, Expect=2e-86]} {Celegans: WBGene00004780, ser-7, SERotonin/octopamine receptor family, [RH, Score=221, Expect=1e-66]} {Smed: dd_Smed_v6_5341_0_1, dd_Smed_v6_5341_0_1, [RH, Score=412, Expect=2e-140]} {RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1310_3896.1, RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1509_11749, RNA1509_13593, RNA1509_37815, RNA815_3010}
6. MligTC455_43745 332 6.92 Mlig455_055372

Neo: -

Age: -

1.941 - - - 0.984 - 0.957 Mlig455_055372 {REF} {Length: 647} {NoTransDecoderORF} {RNA1509_5579} {RNA1310_41512} {RNA815_28753}
7. MligTC455_50425 1754 36.55 Mlig455_021985, Mlig455_031763, Mlig455_051833, Mlig455_063612

Neo: -

Age: Down-Up-Down

1.927 - - - 0.962 - 0.965

Mlig455_021985 {REF} {Length: 394} {TRANSSPLICED} {RNA1509_59895} {RNA1310_900.2} {RNA815_1698.1}

Mlig455_031763 {REF} {Length: 391} {TRANSSPLICED} {RNA1509_59895} {RNA1310_900.2} {RNA815_1698.1}

Mlig455_051833 {REF} {Length: 498} {TRANSSPLICED} {RNA1509_43937} {RNA1310_900.2} {RNA815_1698.1}

Mlig455_063612 {REF} {Length: 710} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_43937} {RNA1310_145253} {RNA815_1698.1}
8. MligTC455_42330 643 13.39 Mlig455_038720

Neo: -

Age: -

1.923 - - - 0.972 - 0.951 Mlig455_038720 {REF} {Length: 2853} {Smed: dd_Smed_v6_6469_0_1, dd_Smed_v6_6469_0_1, [RH, Score=166, Expect=2e-45]} {RNA1509_22744} {RNA1310_6583.1} {RNA815_5360.1}
9. MligTC455_39982 741 15.43 Mlig455_028141

Neo: -

Age: -

1.913 - - - 0.950 - 0.963 Mlig455_028141 {REF} {Length: 1347} {TRANSSPLICED} {RNA1509_21955, RNA1509_28064} {RNA1310_25456, RNA1509_28064} {RNA1509_28064, RNA815_9956}
10. MligTC455_53777 1160 24.18 Mlig455_023453

Neo: -

Age: -

Region-enriched R2: 1.441/0.02700

1.912 - - - 0.964 - 0.948 Mlig455_023453 {REF} {Length: 3263} {TRANSSPLICED} {Pfam: 6-bladed beta-propeller [PF17170.6, score=31.5]; zinc-RING finger domain [PF14634.8, score=25.9]; NHL repeat [PF01436.23, score=24.9]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=24.6]; RING-type zinc-finger [PF13445.8, score=23.6]; Prokaryotic RING finger family 4 [PF14447.8, score=19.6]} {Mouse: ENSMUSG00000031651, Triml1, tripartite motif family-like 1, [Score=49.7, Expect=9e-06]} {RNA1509_17795, RNA1509_5029} {RNA1310_5086.1, RNA1509_17795, RNA1509_5029} {RNA1509_17795, RNA1509_5029, RNA815_4935.1}
11. MligTC455_39983 738 15.37 Mlig455_028268

Neo: -

Age: logFC(26M/2M)=1.160

MRPL17 1.91 - - - 0.950 - 0.960 Mlig455_028268 {REF} {Length: 1311} {TRANSSPLICED} {Pfam: Ribosomal protein L17 [PF01196.21, score=29.7]} {Human: ENSG00000158042, MRPL17, mitochondrial ribosomal protein L17, [RH, Score=57.4, Expect=3e-10]} {Mouse: ENSMUSG00000030879, Mrpl17, mitochondrial ribosomal protein L17, [RH, Score=57.8, Expect=2e-10]} {Dmel: FBgn0035122, mRpL17, mitochondrial ribosomal protein L17, [RH, Score=67.0, Expect=4e-14]} {Smed: dd_Smed_v6_3289_0_1, dd_Smed_v6_3289_0_1, [RH, Score=105, Expect=1e-28]} {RNA1509_21955} {RNA1310_25456} {RNA815_9956}
12. MligTC455_46851 507 10.56 Mlig455_059440

Neo: -

Age: logFC(26M/2M)=-0.309

1.908 - - - 0.953 - 0.955 Mlig455_059440 {REF} {Length: 3521} {TRANSSPLICED} {Pfam: Coiled-coil domain-containing protein 158 [PF15921.7, score=48.5]} {Mouse: ENSMUSG00000050050, Ccdc158, coiled-coil domain containing 158, [RH, Score=85.5, Expect=2e-16]} {Smed: dd_Smed_v6_10831_0_1, dd_Smed_v6_10831_0_1, [RH, Score=72.8, Expect=7e-13]} {RNA1509_28804, RNA1509_7522} {RNA1310_3662, RNA1509_28804} {RNA1509_28804, RNA815_5689}
13. MligTC455_00831 642 13.37 Mlig455_016457, Mlig455_016523

Neo: -

Age: logFC(26M/2M)=0.506

LGR5 1.898 - - - 0.963 - 0.935

Mlig455_016457 {REF} {Length: 4347} {Pfam: Leucine rich repeat [PF13855.8, score=86.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=45.8]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=40.5]} {Human: ENSG00000139292, LGR5, leucine rich repeat containing G protein-coupled receptor 5, [Score=58.5, Expect=7e-08]; ENSG00000145147, SLIT2, slit guidance ligand 2, [Score=57.0, Expect=2e-07]} {Mouse: ENSMUSG00000020140, Lgr5, leucine rich repeat containing G protein coupled receptor 5, [Score=59.7, Expect=2e-08]} {Dmel: FBgn0267435, chp, chaoptin, [Score=67.0, Expect=8e-11]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=55.8, Expect=2e-07]} {RNA1509_8817} {RNA1310_2409} {RNA815_590.1}

Mlig455_016523 {REF} {Length: 3360} {Pfam: Leucine rich repeat [PF13855.8, score=41.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=39.1]} {RNA1509_8817} {RNA1310_22547} {RNA815_590.1}
14. MligTC455_18850 747 15.56 Mlig455_066916

Neo: -

Age: -

1.888 - - - 0.927 - 0.961 Mlig455_066916 {REF} {Length: 1443} {TRANSSPLICED} {Pfam: SUZ domain [PF12752.9, score=43.3]} {RNA1509_41034} {RNA1310_22799} {RNA815_9711.1}
15. MligTC455_44203 530 11.04 Mlig455_025315

Neo: Int S/G2/M

Age: Down-Up-Down

BCKDHA 1.887 - - - 0.950 - 0.937 Mlig455_025315 {REF} {Length: 2202} {TRANSSPLICED} {Pfam: Dehydrogenase E1 component [PF00676.22, score=304.4]; 1-deoxy-D-xylulose-5-phosphate synthase [PF13292.8, score=22.4]; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain [PF02775.23, score=21.2]} {Human: ENSG00000248098, BCKDHA, branched chain keto acid dehydrogenase E1, alpha polypeptide, [RH, Score=500, Expect=6e-176]; ENSG00000255730, AC011462.1, novel protein, [RH, Score=498, Expect=2e-174]} {Mouse: ENSMUSG00000060376, Bckdha, branched chain ketoacid dehydrogenase E1, alpha polypeptide, [RH, Score=502, Expect=7e-177]} {Dmel: FBgn0037709, CG8199, [RH, Score=458, Expect=1e-159]} {Celegans: WBGene00012713, bckd-1A, 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial, [RH, Score=481, Expect=8e-169]} {Smed: dd_Smed_v6_3288_0_1, dd_Smed_v6_3288_0_1, [RH, Score=488, Expect=7e-172]} {RNA1509_21323} {RNA1310_8924.1} {RNA815_7812}
16. MligTC455_47634 862 17.97 Mlig455_003390

Neo: -

Age: -

CNOT4 1.884 - - - 0.954 - 0.930 Mlig455_003390 {REF} {Length: 4850} {TRANSSPLICED} {Pfam: RING/Ubox like zinc-binding domain [PF14570.8, score=68.1]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=20.1]; Ring finger domain [PF13639.8, score=19.9]} {Human: ENSG00000080802, CNOT4, CCR4-NOT transcription complex subunit 4, [RH, Score=306, Expect=2e-92]} {Mouse: ENSMUSG00000038784, Cnot4, CCR4-NOT transcription complex, subunit 4, [RH, Score=306, Expect=1e-92]} {Dmel: FBgn0051716, Cnot4, CCR4-NOT transcription complex subunit 4, [RH, Score=307, Expect=2e-90]} {Celegans: WBGene00003827, ntl-4, NOT-Like (Yeast CCR4/NOT complex component), [RH, Score=276, Expect=7e-81]} {Smed: dd_Smed_v6_4767_0_1, dd_Smed_v6_4767_0_1, [RH, Score=300, Expect=4e-90]} {RNA1509_13345, RNA1509_13404, RNA1509_23912, RNA1509_43015, RNA1509_46728} {RNA1310_5560, RNA1509_13345, RNA1509_23912, RNA1509_43015, RNA1509_46728} {RNA1509_13345, RNA1509_23912, RNA1509_43015, RNA1509_46728, RNA815_2414}
17. MligTC455_12877 194 4.05 Mlig455_003083

Neo: -

Age: -

1.882 - - - 0.964 - 0.918 Mlig455_003083 {REF} {Length: 2223} {NoTransDecoderORF} {RNA1310_65454} {RNA815_34920}
18. MligTC455_15811 819 17.05 Mlig455_041169, Mlig455_070090

Neo: Irradiation

Age: -

Region-enriched R5: 1.715/0.01567

PAQR3 1.881 - - - 0.972 - 0.909

Mlig455_041169 {REF} {Length: 1801} {TRANSSPLICED} {Pfam: Haemolysin-III related [PF03006.22, score=138.2]} {Human: ENSG00000163291, PAQR3, progestin and adipoQ receptor family member 3, [RH, Score=231, Expect=6e-73]} {Mouse: ENSMUSG00000055725, Paqr3, progestin and adipoQ receptor family member III, [RH, Score=228, Expect=4e-72]} {Dmel: FBgn0038256, CG7530, [RH, Score=184, Expect=1e-54]} {Celegans: WBGene00013457, paqr-3, Progestin and AdipoQ Receptor family, [RH, Score=169, Expect=2e-49]} {Smed: dd_Smed_v6_10397_0_1, dd_Smed_v6_10397_0_1, [RH, Score=258, Expect=4e-84]} {RNA1509_27497, RNA1509_31955, RNA1509_44244} {RNA1310_5306, RNA1509_27497, RNA1509_31955, RNA1509_44244} {RNA1509_27497, RNA1509_31955, RNA1509_44244, RNA815_8277}

Mlig455_070090 {REF} {Length: 1600} {Pfam: Haemolysin-III related [PF03006.22, score=138.2]} {Human: ENSG00000163291, PAQR3, progestin and adipoQ receptor family member 3, [RH, Score=231, Expect=6e-73]} {Mouse: ENSMUSG00000055725, Paqr3, progestin and adipoQ receptor family member III, [RH, Score=228, Expect=4e-72]} {Dmel: FBgn0038256, CG7530, [RH, Score=184, Expect=1e-54]} {Celegans: WBGene00013457, paqr-3, Progestin and AdipoQ Receptor family, [RH, Score=169, Expect=2e-49]} {Smed: dd_Smed_v6_10397_0_1, dd_Smed_v6_10397_0_1, [RH, Score=258, Expect=4e-84]} {RNA1509_28463, RNA1509_31955} {RNA1310_5306, RNA1509_28463} {RNA1509_28463, RNA815_8277}
19. MligTC455_45078 694 14.45 Mlig455_014608

Neo: -

Age: -

PGAM5 1.879 - - - 0.951 - 0.928 Mlig455_014608 {REF} {Length: 1364} {TRANSSPLICED} {Pfam: Histidine phosphatase superfamily (branch 1) [PF00300.24, score=64.6]} {Human: ENSG00000247077, PGAM5, PGAM family member 5, mitochondrial serine/threonine protein phosphatase, [Score=165, Expect=1e-48]} {Mouse: ENSMUSG00000029500, Pgam5, phosphoglycerate mutase family member 5, [Score=171, Expect=5e-51]} {Dmel: FBgn0023517, Pgam5, Phosphoglycerate mutase 5, [Score=161, Expect=2e-47]} {Celegans: WBGene00019941, pgam-5, Serine/threonine-protein phosphatase Pgam5, mitochondrial, [Score=160, Expect=2e-47]} {Smed: dd_Smed_v6_6361_0_1, dd_Smed_v6_6361_0_1, [RH, Score=166, Expect=5e-50]} {RNA1509_16698, RNA1509_37206, RNA1509_38229, RNA1509_43050} {RNA1310_22481.1, RNA1509_16698, RNA1509_37206, RNA1509_38229, RNA1509_43050} {RNA1509_16698, RNA1509_37206, RNA1509_38229, RNA1509_43050, RNA815_15679}
20. MligTC455_47977 1528 31.83 Mlig455_060791, Mlig455_060820

Neo: Int S/G2/M

Age: -

FARSA 1.879 - - - 0.969 - 0.910

Mlig455_060791 {REF} {Length: 2199} {Pfam: tRNA synthetases class II core domain (F) [PF01409.22, score=307.5]; PheRS DNA binding domain 3 [PF18553.3, score=68.2]; PheRS DNA binding domain 1 [PF18552.3, score=56.3]; PheRS DNA binding domain 2 [PF18554.3, score=29.9]; Phenylalanyl tRNA synthetase beta chain CLM domain [PF17759.3, score=24.2]; tRNA synthetases class II (D, K and N) [PF00152.22, score=21.0]} {Human: ENSG00000179115, FARSA, phenylalanyl-tRNA synthetase subunit alpha, [RH, Score=652, Expect=0.0]} {Mouse: ENSMUSG00000003808, Farsa, phenylalanyl-tRNA synthetase, alpha subunit, [RH, Score=654, Expect=0.0]} {Dmel: FBgn0030007, alpha-PheRS, Phenylalanyl-tRNA synthetase, alpha-subunit, [RH, Score=619, Expect=0.0]} {Celegans: WBGene00001497, fars-1, Phenylalanyl Amino-acyl tRNA Synthetase, [RH, Score=596, Expect=0.0]} {Smed: dd_Smed_v6_3224_0_1, dd_Smed_v6_3224_0_1, [RH, Score=516, Expect=0.0]} {RNA1509_4587} {RNA1310_10271.1, RNA1509_4587} {RNA1509_4587, RNA815_6726}

Mlig455_060820 {REF} {Length: 2416} {Pfam: tRNA synthetases class II core domain (F) [PF01409.22, score=307.5]; PheRS DNA binding domain 3 [PF18553.3, score=67.2]; PheRS DNA binding domain 1 [PF18552.3, score=56.3]; PheRS DNA binding domain 2 [PF18554.3, score=29.9]; Phenylalanyl tRNA synthetase beta chain CLM domain [PF17759.3, score=24.2]; tRNA synthetases class II (D, K and N) [PF00152.22, score=21.0]} {Human: ENSG00000179115, FARSA, phenylalanyl-tRNA synthetase subunit alpha, [RH, Score=652, Expect=0.0]} {Mouse: ENSMUSG00000003808, Farsa, phenylalanyl-tRNA synthetase, alpha subunit, [RH, Score=653, Expect=0.0]} {Dmel: FBgn0030007, alpha-PheRS, Phenylalanyl-tRNA synthetase, alpha-subunit, [RH, Score=618, Expect=0.0]} {Celegans: WBGene00001497, fars-1, Phenylalanyl Amino-acyl tRNA Synthetase, [RH, Score=595, Expect=0.0]} {Smed: dd_Smed_v6_3224_0_1, dd_Smed_v6_3224_0_1, [RH, Score=515, Expect=1e-180]} {RNA1509_40184} {RNA1310_10271.2, RNA1509_40184} {RNA1509_40184, RNA815_6726}
21. MligTC455_26777 378 7.88 Mlig455_058623

Neo: -

Age: -

KDM8 1.878 - - - 0.956 - 0.922 Mlig455_058623 {REF} {Length: 1880} {TRANSSPLICED} {Pfam: Cupin-like domain [PF13621.8, score=140.2]} {Human: ENSG00000155666, KDM8, lysine demethylase 8, [RH, Score=264, Expect=3e-84]} {Mouse: ENSMUSG00000030752, Kdm8, lysine (K)-specific demethylase 8, [RH, Score=259, Expect=1e-82]} {Dmel: FBgn0035166, CG13902, [RH, Score=201, Expect=3e-60]} {Celegans: WBGene00007387, jmjd-5, JuMonJi (Transcription factor) Domain protein, [RH, Score=216, Expect=1e-64]} {Smed: dd_Smed_v6_5363_0_1, dd_Smed_v6_5363_0_1, [RH, Score=238, Expect=8e-75]} {RNA1509_33307} {RNA1310_14967} {RNA815_36817}
22. MligTC455_53958 458 9.55 Mlig455_006436

Neo: -

Age: Up-Down-Up

KDSR 1.877 - - 0.922 0.955 - - Mlig455_006436 {REF} {Length: 2311} {TRANSSPLICED} {Pfam: short chain dehydrogenase [PF00106.27, score=116.1]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=68.9]; KR domain [PF08659.12, score=50.1]} {Human: ENSG00000119537, KDSR, 3-ketodihydrosphingosine reductase, [RH, Score=213, Expect=5e-66]} {Mouse: ENSMUSG00000009905, Kdsr, 3-ketodihydrosphingosine reductase, [RH, Score=209, Expect=7e-65]} {Dmel: FBgn0039304, CG10425, [RH, Score=162, Expect=5e-47]} {Celegans: WBGene00021367, Y37E11AM.3, [RH, Score=191, Expect=3e-58]} {Smed: dd_Smed_v6_4976_0_1, dd_Smed_v6_4976_0_1, [RH, Score=198, Expect=3e-61]} {RNA1509_50137, RNA1509_51773} {RNA1310_18196, RNA1509_50137} {RNA1509_50137, RNA815_9562}
23. MligTC455_41578 393 8.2 Mlig455_039539

Neo: -

Age: logFC(26M/2M)=-0.259

Region-enriched R5: 1.448/0.04542

MTAP 1.876 - - - 0.967 - 0.909 Mlig455_039539 {REF} {Length: 2227} {Pfam: Phosphorylase superfamily [PF01048.22, score=130.5]} {Human: ENSG00000099810, MTAP, methylthioadenosine phosphorylase, [Score=281, Expect=4e-95]} {Mouse: ENSMUSG00000062937, Mtap, methylthioadenosine phosphorylase, [Score=281, Expect=1e-95]} {Dmel: FBgn0034215, Mtap, Methylthioadenosine phosphorylase, [Score=237, Expect=5e-78]} {Celegans: WBGene00015064, B0228.7, S-methyl-5'-thioadenosine phosphorylase, [Score=185, Expect=9e-58]} {Smed: dd_Smed_v6_2328_0_1, dd_Smed_v6_2328_0_1, [Score=273, Expect=1e-92]} {RNA1509_5160} {RNA1310_30162.1} {RNA815_8250.1}
24. MligTC455_22968 602 12.54 Mlig455_025411

Neo: Int S/G2/M

Age: Up-Down-Down

NCK2 1.87 - - - 0.963 - 0.907 Mlig455_025411 {REF} {Length: 3901} {TRANSSPLICED} {Pfam: SH3 domain [PF00018.30, score=149.7]; Variant SH3 domain [PF14604.8, score=137.1]; Variant SH3 domain [PF07653.19, score=83.1]; SH2 domain [PF00017.26, score=58.0]; Bacterial SH3 domain [PF08239.13, score=33.5]; SH3 domain [PF17902.3, score=28.6]; Bacterial dipeptidyl-peptidase Sh3 domain [PF18348.3, score=18.3]} {Human: ENSG00000071051, NCK2, NCK adaptor protein 2, [RH, Score=226, Expect=1e-68]} {Mouse: ENSMUSG00000032475, Nck1, non-catalytic region of tyrosine kinase adaptor protein 1, [Score=165, Expect=1e-45]} {Dmel: FBgn0010583, dock, dreadlocks, [Score=129, Expect=2e-32]} {Celegans: WBGene00006410, nck-1, NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family, [Score=220, Expect=2e-66]} {Smed: dd_Smed_v6_4816_0_2, dd_Smed_v6_4816_0_2, [Score=214, Expect=6e-62]} {RNA1509_17077, RNA1509_34846, RNA1509_41244} {RNA1310_9858, RNA1509_34846, RNA1509_41244} {RNA1509_34846, RNA1509_41244, RNA815_11879}
25. MligTC455_23275 2207 45.97 Mlig455_023804, Mlig455_029864, Mlig455_066334

Neo: -

Age: Up-Down-Up

PRR9, SCAPER 1.859 - - - 0.963 - 0.896

Mlig455_023804 {REF} {Length: 6866} {TRANSSPLICED} {Pfam: S phase cyclin A-associated protein in the endoplasmic reticulum [PF16501.7, score=92.1]; Zinc-finger of C2H2 type [PF12874.9, score=18.9]} {Human: ENSG00000140386, SCAPER, S-phase cyclin A associated protein in the ER, [RH, Score=326, Expect=4e-91]} {Mouse: ENSMUSG00000034007, Scaper, S phase cyclin A-associated protein in the ER, [RH, Score=231, Expect=6e-61]} {Dmel: FBgn0032723, ssp3, short spindle 3, [RH, Score=130, Expect=7e-30]} {Smed: dd_Smed_v6_6635_0_1, dd_Smed_v6_6635_0_1, [RH, Score=278, Expect=8e-76]} {RNA1509_3503} {RNA1310_1013.1, RNA1509_3503} {RNA1509_3503, RNA815_3463}

Mlig455_029864 {REF} {Length: 379} {Human: ENSG00000203783, PRR9, proline rich 9, [Score=44.7, Expect=3e-06]}

Mlig455_066334 {REF} {Length: 6511} {TRANSSPLICED} {Pfam: S phase cyclin A-associated protein in the endoplasmic reticulum [PF16501.7, score=92.1]; Zinc-finger of C2H2 type [PF12874.9, score=18.9]} {Human: ENSG00000140386, SCAPER, S-phase cyclin A associated protein in the ER, [RH, Score=325, Expect=5e-91]} {Mouse: ENSMUSG00000034007, Scaper, S phase cyclin A-associated protein in the ER, [RH, Score=231, Expect=6e-61]} {Dmel: FBgn0032723, ssp3, short spindle 3, [RH, Score=130, Expect=7e-30]} {Smed: dd_Smed_v6_6635_0_1, dd_Smed_v6_6635_0_1, [RH, Score=278, Expect=8e-76]} {RNA1509_27320, RNA1509_3503, RNA1509_57817} {RNA1310_1013.1, RNA1509_27320, RNA1509_57817} {RNA1509_27320, RNA1509_57817, RNA815_3463}
26. MligTC455_13475 347 7.22 Mlig455_051331

Neo: -

Age: logFC(26M/2M)=-0.343

Region-enriched R4: 2.218/0.00972

MESD 1.853 - - - 0.961 - 0.892 Mlig455_051331 {REF} {Length: 1535} {TRANSSPLICED} {Pfam: Chaperone for wingless signalling and trafficking of LDL receptor [PF10185.11, score=96.9]} {Human: ENSG00000117899, MESD, mesoderm development LRP chaperone, [RH, Score=82.0, Expect=6e-19]} {Mouse: ENSMUSG00000038503, Mesd, mesoderm development LRP chaperone, [RH, Score=82.4, Expect=3e-19]} {Dmel: FBgn0004132, boca, [RH, Score=71.6, Expect=9e-16]} {Smed: dd_Smed_v6_11790_0_1, dd_Smed_v6_11790_0_1, [RH, Score=77.8, Expect=2e-18]} {RNA1509_19060} {RNA1310_9900, RNA1509_19060} {RNA1509_19060, RNA815_3819.1}
27. MligTC455_27572 611 12.73 Mlig455_012550

Neo: -

Age: -

CAPZA2 1.845 - - - 0.953 - 0.892 Mlig455_012550 {REF} {Length: 2749} {Pfam: F-actin capping protein alpha subunit [PF01267.19, score=241.3]} {Human: ENSG00000198898, CAPZA2, capping actin protein of muscle Z-line subunit alpha 2, [RH, Score=199, Expect=5e-62]; ENSG00000116489, CAPZA1, capping actin protein of muscle Z-line subunit alpha 1, [RH, Score=198, Expect=8e-62]} {Mouse: ENSMUSG00000015733, Capza2, capping protein (actin filament) muscle Z-line, alpha 2, [RH, Score=198, Expect=5e-62]; ENSMUSG00000070372, Capza1, capping protein (actin filament) muscle Z-line, alpha 1, [RH, Score=197, Expect=2e-61]} {Dmel: FBgn0034577, cpa, capping protein alpha, [RH, Score=227, Expect=3e-73]} {Celegans: WBGene00000292, cap-1, F-actin-capping protein subunit alpha, [RH, Score=192, Expect=7e-60]} {Smed: dd_Smed_v6_2399_0_1, dd_Smed_v6_2399_0_1, [RH, Score=188, Expect=3e-58]} {RNA1509_45500, RNA1509_8477} {RNA1310_17444, RNA1509_45500} {RNA1509_45500, RNA815_6606.1}
28. MligTC455_09773 633 13.18 Mlig455_031595

Neo: -

Age: -

1.84 - - - 0.960 - 0.880 Mlig455_031595 {REF} {Length: 1992} {RNA1509_30983} {RNA1310_27418, RNA1509_30983} {RNA1509_30983, RNA815_40613}
29. MligTC455_28702 789 16.43 Mlig455_021393

Neo: -

Age: logFC(26M/2M)=0.303

CLTC 1.837 - - - 0.955 - 0.882 Mlig455_021393 {REF} {Length: 7603} {Pfam: Region in Clathrin and VPS [PF00637.22, score=638.4]; Clathrin propeller repeat [PF01394.22, score=136.0]; Clathrin-H-link [PF13838.8, score=108.9]; Clathrin, heavy-chain linker [PF09268.12, score=45.8]; Coatomer WD associated region [PF04053.16, score=31.1]} {Human: ENSG00000141367, CLTC, clathrin heavy chain, [RH, Score=2731, Expect=0.0]} {Mouse: ENSMUSG00000047126, Cltc, clathrin, heavy polypeptide (Hc), [RH, Score=2731, Expect=0.0]} {Dmel: FBgn0000319, Chc, Clathrin heavy chain, [RH, Score=2615, Expect=0.0]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [RH, Score=2412, Expect=0.0]} {Smed: dd_Smed_v6_59_0_1, dd_Smed_v6_59_0_1, [RH, Score=2760, Expect=0.0]} {RNA1509_14831} {RNA1310_1023.1} {RNA815_198.1}
30. MligTC455_26432 1498 31.21 Mlig455_070327

Neo: -

Age: Down-Up-Up

1.832 - - 0.850 0.982 - - Mlig455_070327 {REF} {Length: 1200} {NoTransDecoderORF} {RNA1509_11441, RNA1509_19097, RNA1509_46968} {RNA1310_49149.2, RNA1509_11441, RNA1509_19097, RNA1509_46968} {RNA1509_11441, RNA1509_19097, RNA1509_46968, RNA815_25016}
31. MligTC455_50793 1150 23.96 Mlig455_050628

Neo: -

Age: -

1.832 - - - 0.964 - 0.868 Mlig455_050628 {REF} {Length: 1302} {TRANSSPLICED} {RNA1509_14468, RNA1509_9990} {RNA1310_27653, RNA1509_14468, RNA1509_9990} {RNA1509_14468, RNA1509_9990, RNA815_14056}
32. MligTC455_12816 505 10.52 Mlig455_011135

Neo: Germline

Age: -

Region-specific R4: 5.116

Region-enriched R4: 3.123/0.00123

HMCN1 1.831 - - - 0.954 - 0.877 Mlig455_011135 {REF} {Length: 1704} {TRANSSPLICED} {Pfam: Thrombospondin type 1 domain [PF00090.21, score=22.9]; Immunoglobulin V-set domain [PF07686.19, score=21.4]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=61.2, Expect=4e-09]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=54.7, Expect=3e-07]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [Score=50.4, Expect=3e-06]} {RNA1509_13517} {RNA1310_16918} {RNA815_22557}
33. MligTC455_39174 766 15.96 Mlig455_051976

Neo: -

Age: logFC(26M/2M)=-0.264

KLHL20 1.826 - - - 0.957 - 0.869 Mlig455_051976 {REF} {Length: 3608} {Pfam: Kelch motif [PF01344.27, score=277.5]; BTB And C-terminal Kelch [PF07707.17, score=124.7]; Kelch motif [PF13964.8, score=116.6]; BTB/POZ domain [PF00651.33, score=108.7]; Galactose oxidase, central domain [PF13415.8, score=69.4]; Galactose oxidase, central domain [PF13418.8, score=65.5]; Kelch motif [PF07646.17, score=59.0]} {Human: ENSG00000076321, KLHL20, kelch like family member 20, [RH, Score=884, Expect=0.0]} {Mouse: ENSMUSG00000026705, Klhl20, kelch-like 20, [RH, Score=884, Expect=0.0]} {Dmel: FBgn0040230, dbo, diablo, [RH, Score=857, Expect=0.0]} {Celegans: WBGene00020030, R12E2.1, [RH, Score=708, Expect=0.0]} {Smed: dd_Smed_v6_6164_0_1, dd_Smed_v6_6164_0_1, [RH, Score=881, Expect=0.0]} {RNA1509_14674, RNA1509_34040, RNA1509_34907, RNA1509_54335} {RNA1310_8392, RNA1509_14674, RNA1509_34040, RNA1509_34907, RNA1509_54335} {RNA1509_14674, RNA1509_34040, RNA1509_34907, RNA1509_54335, RNA815_4073}
34. MligTC455_17738 600 12.49 Mlig455_005267

Neo: -

Age: Up-Down-Up

PKNOX2 1.824 - - - 0.969 - 0.855 Mlig455_005267 {REF} {Length: 4191} {Pfam: Homeobox KN domain [PF05920.13, score=68.1]; N-terminal of Homeobox Meis and PKNOX1 [PF16493.7, score=55.5]; Homeodomain [PF00046.31, score=30.5]} {Human: ENSG00000165495, PKNOX2, PBX/knotted 1 homeobox 2, [RH, Score=209, Expect=1e-59]} {Mouse: ENSMUSG00000035934, Pknox2, Pbx/knotted 1 homeobox 2, [RH, Score=209, Expect=2e-59]} {Dmel: FBgn0001235, hth, homothorax, [Score=117, Expect=1e-27]} {Celegans: WBGene00006796, unc-62, Homeobox protein unc-62, [Score=107, Expect=3e-24]} {Smed: dd_Smed_v6_8606_0_1, dd_Smed_v6_8606_0_1, [Score=258, Expect=2e-75]} {RNA1509_58890} {RNA1310_1426.1} {RNA815_7214}
35. MligTC455_26788 823 17.15 Mlig455_009191

Neo: Irradiation

Age: Up-Down-Down

Region-enriched R4: 1.115/0.02113

1.824 - - - 0.962 - 0.862 Mlig455_009191 {REF} {Length: 11487} {TRANSSPLICED} {Dmel: FBgn0086690, Plp, Pericentrin-like protein, [Score=52.0, Expect=5e-06]} {RNA1509_5275} {RNA1310_379.1} {RNA815_407.1}
36. MligTC455_17108 1081 22.52 Mlig455_045167

Neo: -

Age: logFC(26M/2M)=0.316

RAPGEF1 1.806 - - - 0.959 - 0.847 Mlig455_045167 {REF} {Length: 4776} {TRANSSPLICED} {Pfam: RasGEF domain [PF00617.21, score=84.9]} {Human: ENSG00000107263, RAPGEF1, Rap guanine nucleotide exchange factor 1, [RH, Score=185, Expect=3e-47]} {Mouse: ENSMUSG00000039844, Rapgef1, Rap guanine nucleotide exchange factor (GEF) 1, [RH, Score=187, Expect=6e-48]} {Dmel: FBgn0259228, C3G, C3G guanyl-nucleotide exchange factor, [RH, Score=165, Expect=5e-41]} {Celegans: WBGene00021320, Y34B4A.4, [RH, Score=174, Expect=1e-44]} {Smed: dd_Smed_v6_11351_0_1, dd_Smed_v6_11351_0_1, [RH, Score=128, Expect=2e-30]} {RNA1509_14166, RNA1509_14480} {RNA1310_2752.1, RNA1509_14166, RNA1509_14480} {RNA1509_14166, RNA1509_14480, RNA815_12010.1}
37. MligTC455_28982 15213 316.93 Mlig455_025642

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=2.852

1.8 - - - 0.956 - 0.844 Mlig455_025642 {REF} {Length: 195} {NoTransDecoderORF} {RNA1509_892} {RNA1310_53106.5} {RNA815_11555.1}
38. MligTC455_38244 734 15.29 Mlig455_022877

Neo: -

Age: Down-Up-Down

TRAPPC3 1.798 - - - 0.847 - 0.951 Mlig455_022877 {REF} {Length: 1976} {TRANSSPLICED} {Pfam: Transport protein particle (TRAPP) component [PF04051.18, score=107.6]} {Human: ENSG00000054116, TRAPPC3, trafficking protein particle complex 3, [RH, Score=234, Expect=6e-79]} {Mouse: ENSMUSG00000028847, Trappc3, trafficking protein particle complex 3, [RH, Score=235, Expect=3e-79]} {Dmel: FBgn0260859, Bet3, Blocked early in transport 3, [RH, Score=207, Expect=3e-68]} {Celegans: WBGene00014222, trpp-3, Trafficking protein particle complex subunit 3 homolog, [Score=143, Expect=2e-43]} {Smed: dd_Smed_v6_4848_0_1, dd_Smed_v6_4848_0_1, [RH, Score=219, Expect=4e-73]} {RNA1509_14723} {RNA1310_13044} {RNA815_24609}
39. MligTC455_23551 537 11.19 Mlig455_007655

Neo: -

Age: -

CSNK1G1 1.789 - - 0.839 0.950 - - Mlig455_007655 {REF} {Length: 4258} {Pfam: Protein kinase domain [PF00069.27, score=100.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=55.0]; Fungal protein kinase [PF17667.3, score=29.3]} {Human: ENSG00000169118, CSNK1G1, casein kinase 1 gamma 1, [RH, Score=527, Expect=0.0]; ENSG00000151292, CSNK1G3, casein kinase 1 gamma 3, [RH, Score=521, Expect=0.0]} {Mouse: ENSMUSG00000032384, Csnk1g1, casein kinase 1, gamma 1, [RH, Score=535, Expect=0.0]; ENSMUSG00000073563, Csnk1g3, casein kinase 1, gamma 3, [RH, Score=518, Expect=0.0]} {Dmel: FBgn0250823, gish, gilgamesh, [RH, Score=508, Expect=4e-178]} {Celegans: WBGene00013709, csnk-1, Casein kinase I gamma, [RH, Score=512, Expect=0.0]} {Smed: dd_Smed_v6_8508_0_2, dd_Smed_v6_8508_0_2, [RH, Score=462, Expect=2e-161]} {RNA1509_16024, RNA1509_20026} {RNA1310_20582.1, RNA1509_16024} {RNA1509_16024, RNA815_13120.1}
40. MligTC455_48867 274 5.71 Mlig455_052014

Neo: -

Age: -

CAPS2 1.788 - - - 0.976 - 0.812 Mlig455_052014 {REF} {Length: 3413} {TRANSSPLICED} {Human: ENSG00000180881, CAPS2, calcyphosine 2, [RH, Score=207, Expect=4e-60]} {Mouse: ENSMUSG00000035694, Caps2, calcyphosphine 2, [RH, Score=225, Expect=6e-65]} {Dmel: FBgn0051345, CG31345, [Score=63.5, Expect=5e-11]} {Smed: dd_Smed_v6_7209_0_1, dd_Smed_v6_7209_0_1, [Score=70.9, Expect=7e-14]} {RNA1509_44692} {RNA1310_9646.2, RNA1509_44692} {RNA1509_44692, RNA815_2138.1}
41. MligTC455_23552 539 11.23 Mlig455_020886

Neo: Irradiation

Age: -

CSNK1G1 1.788 - - 0.838 0.950 - - Mlig455_020886 {REF} {Length: 4055} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=100.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=55.0]; Fungal protein kinase [PF17667.3, score=29.4]} {Human: ENSG00000169118, CSNK1G1, casein kinase 1 gamma 1, [RH, Score=527, Expect=0.0]; ENSG00000151292, CSNK1G3, casein kinase 1 gamma 3, [RH, Score=524, Expect=0.0]} {Mouse: ENSMUSG00000032384, Csnk1g1, casein kinase 1, gamma 1, [RH, Score=535, Expect=0.0]; ENSMUSG00000073563, Csnk1g3, casein kinase 1, gamma 3, [RH, Score=520, Expect=0.0]} {Dmel: FBgn0250823, gish, gilgamesh, [RH, Score=515, Expect=0.0]} {Celegans: WBGene00013709, csnk-1, Casein kinase I gamma, [RH, Score=513, Expect=0.0]} {Smed: dd_Smed_v6_8508_0_2, dd_Smed_v6_8508_0_2, [RH, Score=462, Expect=1e-161]} {RNA1509_20026, RNA1509_31077} {RNA1310_19544.3, RNA1509_31077} {RNA1509_31077, RNA815_13120.1}
42. MligTC455_00679 246 5.12 Mlig455_028787

Neo: -

Age: -

1.783 - - - 0.959 - 0.824 Mlig455_028787 {REF} {Length: 537} {RNA1509_35184} {RNA1310_31249} {RNA815_18932.1}
43. MligTC455_31339 445 9.27 Mlig455_006071, Mlig455_053223

Neo: -

Age: -

NYNRIN, POLM 1.777 - - - 0.967 - 0.810

Mlig455_006071 {REF} {Length: 7416} {Pfam: DNA polymerase beta thumb [PF14791.8, score=75.5]; Integrase zinc binding domain [PF17921.3, score=59.0]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=54.0]; Integrase core domain [PF00665.28, score=45.1]; Fingers domain of DNA polymerase lambda [PF10391.11, score=24.2]; DNA polymerase beta palm [PF14792.8, score=20.8]} {Human: ENSG00000122678, POLM, DNA polymerase mu, [Score=214, Expect=3e-59]} {Mouse: ENSMUSG00000020474, Polm, polymerase (DNA directed), mu, [RH, Score=229, Expect=2e-64]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=127, Expect=2e-29]} {RNA1509_18343} {RNA1310_8091.1} {RNA815_3041}

Mlig455_053223 {REF} {Length: 2426} {Pfam: Integrase zinc binding domain [PF17921.3, score=61.1]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=55.1]; Integrase core domain [PF00665.28, score=46.3]; Integrase core domain [PF13683.8, score=18.4]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=90.9, Expect=6e-18]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=94.0, Expect=4e-19]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=118, Expect=4e-27]} {RNA1509_18367} {RNA1310_1117.1} {RNA815_895.1}
44. MligTC455_52953 200 4.16 Mlig455_020418

Neo: -

Age: -

1.775 - - 0.816 0.959 - - Mlig455_020418 {REF} {Length: 532} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_57020} {RNA1310_45915} {RNA815_51517}
45. MligTC455_18849 285 5.93 Mlig455_019510

Neo: -

Age: -

1.766 - - 0.806 0.960 - - Mlig455_019510 {REF} {Length: 1502} {TRANSSPLICED} {Pfam: SUZ domain [PF12752.9, score=43.3]} {RNA1509_41034} {RNA1310_40561} {RNA815_9711.1}
46. MligTC455_39376 626 13.04 Mlig455_039473

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.343

Region-enriched R5: 1.874/0.00059
Region-enriched R4: 1.747/0.01145

FUCA2 1.763 - - 0.796 0.967 - - Mlig455_039473 {REF} {Length: 3228} {TRANSSPLICED} {Pfam: Alpha-L-fucosidase [PF01120.19, score=414.4]; Alpha-L-fucosidase C-terminal domain [PF16757.7, score=71.4]} {Human: ENSG00000001036, FUCA2, alpha-L-fucosidase 2, [RH, Score=541, Expect=0.0]; ENSG00000179163, FUCA1, alpha-L-fucosidase 1, [RH, Score=519, Expect=0.0]} {Mouse: ENSMUSG00000019810, Fuca2, fucosidase, alpha-L- 2, plasma, [RH, Score=534, Expect=0.0]; ENSMUSG00000028673, Fuca1, fucosidase, alpha-L- 1, tissue, [RH, Score=516, Expect=0.0]} {Dmel: FBgn0285958, Fuca, alpha-L-fucosidase, [RH, Score=464, Expect=1e-160]} {Celegans: WBGene00012225, W03G11.3, Putative alpha-L-fucosidase, [RH, Score=422, Expect=2e-144]} {Smed: dd_Smed_v6_8422_0_1, dd_Smed_v6_8422_0_1, [RH, Score=540, Expect=0.0]} {RNA1509_32265, RNA1509_55653, RNA1509_6158} {RNA1310_6463, RNA1509_32265, RNA1509_55653} {RNA1509_32265, RNA1509_55653, RNA815_1561}
47. MligTC455_05237 434 9.03 Mlig455_062019, Mlig455_063223, Mlig455_067366

Neo: -

Age: logFC(26M/2M)=0.268

Region-enriched R2: 3.012/0.04675

1.759 - - - 0.954 - 0.805

Mlig455_062019 {REF} {Length: 5306} {Pfam: Alkyl sulfatase dimerisation [PF14863.8, score=117.3]; Metallo-beta-lactamase superfamily [PF00753.29, score=66.9]; WD domain, G-beta repeat [PF00400.34, score=26.9]; Beta-lactamase superfamily domain [PF12706.9, score=23.5]} {RNA1509_5018} {RNA1310_8833} {RNA815_3106.1}

Mlig455_063223 {REF} {Length: 6782} {Pfam: Alkyl sulfatase dimerisation [PF14863.8, score=116.8]; Metallo-beta-lactamase superfamily [PF00753.29, score=67.6]; WD domain, G-beta repeat [PF00400.34, score=36.0]; Alkyl sulfatase C-terminal [PF14864.8, score=24.6]; Beta-lactamase superfamily domain [PF12706.9, score=23.3]} {RNA1509_5018} {RNA1310_8833} {RNA815_3106.1}

Mlig455_067366 {REF} {Length: 6771} {Pfam: Alkyl sulfatase dimerisation [PF14863.8, score=117.8]; Metallo-beta-lactamase superfamily [PF00753.29, score=66.2]; WD domain, G-beta repeat [PF00400.34, score=33.0]; Alkyl sulfatase C-terminal [PF14864.8, score=24.5]; Beta-lactamase superfamily domain [PF12706.9, score=23.2]} {RNA1509_50108, RNA1509_5018} {RNA1310_8833, RNA1509_50108} {RNA1509_50108, RNA815_3106.1}
48. MligTC455_46731 237 4.94 Mlig455_009017

Neo: -

Age: -

ARFGAP1 1.757 - - 0.783 0.974 - - Mlig455_009017 {REF} {Length: 3384} {Pfam: Putative GTPase activating protein for Arf [PF01412.20, score=29.7]} {Human: ENSG00000101199, ARFGAP1, ADP ribosylation factor GTPase activating protein 1, [Score=161, Expect=1e-44]} {Mouse: ENSMUSG00000027575, Arfgap1, ADP-ribosylation factor GTPase activating protein 1, [Score=158, Expect=1e-43]} {Dmel: FBgn0020655, ArfGAP1, ADP-ribosylation factor GTPase activating protein 1, [Score=205, Expect=9e-61]} {Celegans: WBGene00010500, K02B12.7, [Score=137, Expect=5e-36]} {Smed: dd_Smed_v6_539_0_1, dd_Smed_v6_539_0_1, [Score=50.8, Expect=8e-07]} {RNA1509_3768} {RNA1310_4307.1} {RNA815_7335}
49. MligTC455_22308 1182 24.63 Mlig455_009243

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.663

1.756 - - 0.789 - - 0.967 Mlig455_009243 {REF} {Length: 2029} {RNA1509_466} {RNA1310_10184.1} {RNA815_3434}
50. MligTC455_16899 789 16.45 Mlig455_054163, Mlig455_060701

Neo: -

Age: -

1.755 - - - 0.960 - 0.795

Mlig455_054163 {REF} {Length: 1573} {RNA1509_32433} {RNA1310_22335} {RNA815_10376}

Mlig455_060701 {REF} {Length: 1510} {RNA1509_32433} {RNA1310_22335} {RNA815_10376}
51. MligTC455_47312 355 7.4 Mlig455_010188

Neo: -

Age: Up-Down-Down

LUC7L 1.754 - - - 0.965 - 0.789 Mlig455_010188 {REF} {Length: 2587} {Pfam: LUC7 N_terminus [PF03194.17, score=239.6]} {Human: ENSG00000007392, LUC7L, LUC7 like, [RH, Score=304, Expect=5e-99]; ENSG00000146963, LUC7L2, LUC7 like 2, pre-mRNA splicing factor, [RH, Score=293, Expect=9e-95]} {Mouse: ENSMUSG00000024188, Luc7l, Luc7-like, [RH, Score=303, Expect=9e-99]; ENSMUSG00000029823, Luc7l2, LUC7-like 2 (S. cerevisiae), [RH, Score=290, Expect=3e-94]} {Dmel: FBgn0036734, CG7564, [RH, Score=306, Expect=2e-99]} {Celegans: WBGene00015207, B0495.8, [RH, Score=161, Expect=3e-45]} {Smed: dd_Smed_v6_4536_0_4, dd_Smed_v6_4536_0_4, [RH, Score=300, Expect=3e-99]} {RNA1509_894} {RNA1310_9024.1} {RNA815_807.1}
52. MligTC455_23327 608 12.68 Mlig455_023520, Mlig455_023556

Neo: -

Age: -

Region-enriched R4: 2.430/0.01938

STAG1 1.751 - - 0.801 - - 0.950

Mlig455_023520 {REF} {Length: 5954} {Pfam: STAG domain [PF08514.13, score=109.8]} {Human: ENSG00000118007, STAG1, stromal antigen 1, [RH, Score=902, Expect=0.0]; ENSG00000101972, STAG2, stromal antigen 2, [RH, Score=895, Expect=0.0]} {Mouse: ENSMUSG00000037286, Stag1, stromal antigen 1, [RH, Score=902, Expect=0.0]; ENSMUSG00000025862, Stag2, stromal antigen 2, [RH, Score=899, Expect=0.0]} {Dmel: FBgn0020616, SA, Stromalin, [RH, Score=852, Expect=0.0]} {Celegans: WBGene00004738, scc-3, Cohesin subunit scc-3, [RH, Score=610, Expect=0.0]} {Smed: dd_Smed_v6_7280_0_1, dd_Smed_v6_7280_0_1, [RH, Score=1004, Expect=0.0]} {RNA1509_2739} {RNA1310_911.1} {RNA815_315}

Mlig455_023556 {REF} {Length: 5995} {Pfam: STAG domain [PF08514.13, score=109.9]} {Human: ENSG00000118007, STAG1, stromal antigen 1, [RH, Score=912, Expect=0.0]; ENSG00000101972, STAG2, stromal antigen 2, [RH, Score=902, Expect=0.0]} {Mouse: ENSMUSG00000037286, Stag1, stromal antigen 1, [RH, Score=911, Expect=0.0]; ENSMUSG00000025862, Stag2, stromal antigen 2, [RH, Score=905, Expect=0.0]} {Dmel: FBgn0020616, SA, Stromalin, [RH, Score=855, Expect=0.0]} {Celegans: WBGene00004738, scc-3, Cohesin subunit scc-3, [RH, Score=612, Expect=0.0]} {Smed: dd_Smed_v6_7280_0_1, dd_Smed_v6_7280_0_1, [RH, Score=1007, Expect=0.0]} {RNA1509_2739} {RNA1310_911.1, RNA1509_2739} {RNA1509_2739, RNA815_315}
53. MligTC455_28988 26527 552.65 Mlig455_025218

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=5.957

1.747 - - - 0.952 - 0.795 Mlig455_025218 {REF} {Length: 333} {NoTransDecoderORF} {RNA1509_892} {RNA1310_53106.5} {RNA815_11555.1}
54. MligTC455_38664 290 6.05 Mlig455_052362

Neo: Irradiation

Age: -

Region-enriched R5: 1.345/0.01260

SLC4A1AP 1.739 - - 0.784 0.955 - - Mlig455_052362 {REF} {Length: 3656} {Pfam: FHA domain [PF00498.28, score=67.1]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=24.7]; Dicer dimerisation domain [PF03368.16, score=21.2]} {Human: ENSG00000163798, SLC4A1AP, solute carrier family 4 member 1 adaptor protein, [RH, Score=262, Expect=6e-76]} {Mouse: ENSMUSG00000029141, Slc4a1ap, solute carrier family 4 (anion exchanger), member 1, adaptor protein, [RH, Score=252, Expect=2e-72]} {Dmel: FBgn0038640, CG7706, [RH, Score=224, Expect=8e-63]} {Celegans: WBGene00014011, ZK632.2, [RH, Score=169, Expect=8e-44]} {Smed: dd_Smed_v6_8435_0_1, dd_Smed_v6_8435_0_1, [Score=273, Expect=5e-82]} {RNA1509_15385, RNA1509_36632, RNA1509_37617, RNA1509_58889} {RNA1310_8436, RNA1509_15385, RNA1509_36632, RNA1509_37617, RNA1509_58889} {RNA1509_15385, RNA1509_36632, RNA1509_37617, RNA1509_58889, RNA815_10628}
55. MligTC455_50529 987 20.57 Mlig455_017364

Neo: -

Age: Up-Up-Down

1.727 - - - 0.956 - 0.771 Mlig455_017364 {REF} {Length: 724} {NoTransDecoderORF} {RNA1509_11669} {RNA1310_22552} {RNA815_27885}
56. MligTC455_25021 137 2.86 Mlig455_008215

Neo: -

Age: Down-Up-Up

1.724 - - 0.770 0.954 - - Mlig455_008215 {REF} {Length: 725} {Pfam: Transglutaminase family [PF00868.22, score=45.1]} {Dmel: FBgn0031975, Tg, Transglutaminase, [Score=46.2, Expect=5e-07]} {RNA1509_27288} {RNA1310_46156} {RNA815_13515.1}
57. MligTC455_50530 2119 44.14 Mlig455_030950, Mlig455_034364

Neo: -

Age: -

1.717 - - - 0.958 - 0.759

Mlig455_030950 {REF} {Length: 7693} {TRANSSPLICED} {RNA1509_37969} {RNA1310_1070} {RNA815_2258.1}

Mlig455_034364 {REF} {Length: 7847} {TRANSSPLICED} {RNA1509_26045, RNA1509_28270, RNA1509_37812} {RNA1310_952, RNA1509_26045, RNA1509_37812} {RNA1509_26045, RNA1509_37812, RNA815_2258.1}
58. MligTC455_36118 8835 184.05 Mlig455_045360

Neo: -

Age: -

TMBIM6 1.713 - 0.759 - 0.954 - - Mlig455_045360 {REF} {Length: 2231} {TRANSSPLICED} {Pfam: Inhibitor of apoptosis-promoting Bax1 [PF01027.22, score=116.1]} {Human: ENSG00000139644, TMBIM6, transmembrane BAX inhibitor motif containing 6, [RH, Score=133, Expect=1e-37]} {Mouse: ENSMUSG00000023010, Tmbim6, transmembrane BAX inhibitor motif containing 6, [RH, Score=142, Expect=2e-41]} {Dmel: FBgn0035871, BI-1, Bax Inhibitor-1, [RH, Score=123, Expect=4e-34]} {Smed: dd_Smed_v6_319_0_1, dd_Smed_v6_319_0_1, [RH, Score=165, Expect=7e-51]} {RNA1509_14502, RNA1509_59844} {RNA1310_27138, RNA1509_59844} {RNA1509_59844, RNA815_14503}
59. MligTC455_32972 570 11.88 Mlig455_067598

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.773

1.711 - - 0.735 0.976 - - Mlig455_067598 {REF} {Length: 3556} {TRANSSPLICED} {RNA1509_7347} {RNA1310_9409} {RNA815_7739}
60. MligTC455_40359 779 16.23 Mlig455_025110

Neo: -

Age: -

SNX33 1.711 - - 0.751 0.960 - - Mlig455_025110 {REF} {Length: 4134} {Pfam: WASP-binding domain of Sorting nexin protein [PF10456.11, score=185.6]; PX domain [PF00787.26, score=62.1]; SH3 domain [PF00018.30, score=48.9]; Variant SH3 domain [PF14604.8, score=48.1]; Variant SH3 domain [PF07653.19, score=40.9]} {Human: ENSG00000173548, SNX33, sorting nexin 33, [RH, Score=279, Expect=9e-86]} {Mouse: ENSMUSG00000002365, Snx9, sorting nexin 9, [RH, Score=256, Expect=5e-77]; ENSMUSG00000042364, Snx18, sorting nexin 18, [RH, Score=253, Expect=2e-75]} {Dmel: FBgn0040475, SH3PX1, SH3 and PX domain containing 1, [RH, Score=261, Expect=5e-79]} {Celegans: WBGene00003086, lst-4, Sorting nexin lst-4, [Score=216, Expect=1e-62]} {Smed: dd_Smed_v6_2732_0_1, dd_Smed_v6_2732_0_1, [Score=236, Expect=2e-70]} {RNA1509_11409, RNA1509_45683, RNA1509_47652} {RNA1310_5754, RNA1509_45683, RNA1509_47652} {RNA1509_45683, RNA1509_47652, RNA815_7676.1}
61. MligTC455_39605 496 10.34 Mlig455_062588

Neo: -

Age: -

CASP3 1.697 - - 0.732 0.965 - - Mlig455_062588 {REF} {Length: 2819} {TRANSSPLICED} {Pfam: Caspase domain [PF00656.24, score=128.5]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=207, Expect=1e-65]; ENSG00000165806, CASP7, caspase 7, [Score=205, Expect=9e-65]} {Mouse: ENSMUSG00000025076, Casp7, caspase 7, [Score=210, Expect=1e-66]; ENSMUSG00000031628, Casp3, caspase 3, [Score=206, Expect=4e-65]} {Dmel: FBgn0010501, Dcp-1, Death caspase-1, [Score=184, Expect=2e-56]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=108, Expect=5e-28]} {Smed: dd_Smed_v6_3121_1_1, dd_Smed_v6_3121_1_1, [Score=160, Expect=7e-48]} {RNA1509_15108, RNA1509_45726} {RNA1310_29553, RNA1509_15108, RNA1509_45726} {RNA1509_15108, RNA1509_45726, RNA815_13205.1}
62. MligTC455_17185 1203 25.06 Mlig455_043379, Mlig455_043547

Neo: -

Age: -

Region-enriched R3: 2.698/0.00014
Region-enriched R6: 2.303/0.00650

1.695 - - - 0.951 - 0.744

Mlig455_043379 {REF} {Length: 1593} {Pfam: YhhN family [PF07947.16, score=80.0]} {Dmel: FBgn0039681, CG7582, [Score=52.4, Expect=6e-08]} {Smed: dd_Smed_v6_11970_0_1, dd_Smed_v6_11970_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_28364} {RNA1310_11695.1} {RNA815_14610}

Mlig455_043547 {REF} {Length: 2226} {Pfam: YhhN family [PF07947.16, score=80.0]} {Dmel: FBgn0039681, CG7582, [Score=52.4, Expect=6e-08]} {Smed: dd_Smed_v6_11970_0_1, dd_Smed_v6_11970_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_28364, RNA1509_37355} {RNA1310_11695.1, RNA1509_37355} {RNA1509_37355, RNA815_14610}
63. MligTC455_04860 2094 43.62 Mlig455_024949

Neo: -

Age: -

LITAF 1.692 - - - 0.953 0.739 - Mlig455_024949 {REF} {Length: 2362} {TRANSSPLICED} {Pfam: LITAF-like zinc ribbon domain [PF10601.11, score=80.8]} {Human: ENSG00000189067, LITAF, lipopolysaccharide induced TNF factor, [Score=61.6, Expect=3e-12]} {Mouse: ENSMUSG00000022500, Litaf, LPS-induced TN factor, [Score=63.5, Expect=4e-13]} {Dmel: FBgn0050273, CG30273, [RH, Score=77.0, Expect=9e-19]} {Celegans: WBGene00012549, Y37D8A.8, [RH, Score=57.4, Expect=2e-11]} {Smed: dd_Smed_v6_10754_0_1, dd_Smed_v6_10754_0_1, [RH, Score=82.0, Expect=6e-21]} {RNA1509_38480, RNA1509_58765, RNA1509_58780, RNA1509_7303} {RNA1310_18499.1, RNA1509_38480, RNA1509_58765, RNA1509_58780} {RNA1509_38480, RNA1509_58765, RNA1509_58780, RNA815_28299}
64. MligTC455_52052 1717 35.78 Mlig455_057784

Neo: -

Age: -

1.692 - - 0.731 - - 0.961 Mlig455_057784 {REF} {Length: 1949} {TRANSSPLICED} {Pfam: Universal stress protein family [PF00582.28, score=69.0]} {Smed: dd_Smed_v6_1092_0_1, dd_Smed_v6_1092_0_1, [Score=85.1, Expect=5e-21]} {RNA1509_19601, RNA1509_22256, RNA1509_31639, RNA1509_9185} {RNA1310_15109.1, RNA1509_19601, RNA1509_22256, RNA1509_31639, RNA1509_9185} {RNA1509_19601, RNA1509_22256, RNA1509_31639, RNA1509_9185, RNA815_6173}
65. MligTC455_53206 1500 31.25 Mlig455_050751

Neo: -

Age: -

WASHC2C 1.684 - - - 0.967 - 0.717 Mlig455_050751 {REF} {Length: 6565} {TRANSSPLICED} {Pfam: Cornifin (SPRR) family [PF02389.17, score=27.8]} {Human: ENSG00000172661, WASHC2C, WASH complex subunit 2C, [RH, Score=154, Expect=4e-37]; ENSG00000099290, WASHC2A, WASH complex subunit 2A, [RH, Score=154, Expect=3e-37]} {Mouse: ENSMUSG00000024104, Washc2, WASH complex subunit 2`, [RH, Score=160, Expect=4e-39]} {Smed: dd_Smed_v6_3045_0_1, dd_Smed_v6_3045_0_1, [RH, Score=130, Expect=2e-30]} {RNA1509_15626, RNA1509_18962, RNA1509_25256, RNA1509_32419, RNA1509_41029, RNA1509_46567, RNA1509_56097} {RNA1310_3749, RNA1509_15626, RNA1509_18962, RNA1509_25256, RNA1509_32419, RNA1509_41029, RNA1509_46567, RNA1509_56097} {RNA1509_15626, RNA1509_18962, RNA1509_25256, RNA1509_32419, RNA1509_41029, RNA1509_46567, RNA1509_56097, RNA815_12544}
66. MligTC455_10137 542 11.28 Mlig455_028902

Neo: Int S/G2/M

Age: -

MPDU1 1.683 - - 0.730 0.953 - - Mlig455_028902 {REF} {Length: 4121} {TRANSSPLICED} {Pfam: PQ loop repeat [PF04193.16, score=73.8]} {Human: ENSG00000129255, MPDU1, mannose-P-dolichol utilization defect 1, [RH, Score=214, Expect=2e-69]} {Mouse: ENSMUSG00000018761, Mpdu1, mannose-P-dolichol utilization defect 1, [RH, Score=236, Expect=6e-78]} {Dmel: FBgn0031662, CG3792, [RH, Score=207, Expect=7e-67]} {Celegans: WBGene00018181, F38E1.9, Mannose-P-dolichol utilization defect 1 protein homolog, [RH, Score=180, Expect=3e-56]} {Smed: dd_Smed_v6_5696_0_1, dd_Smed_v6_5696_0_1, [RH, Score=218, Expect=5e-71]} {RNA1509_25731, RNA1509_33404, RNA1509_34616, RNA1509_35220} {RNA1310_38110, RNA1509_25731, RNA1509_33404, RNA1509_34616, RNA1509_35220} {RNA1509_25731, RNA1509_33404, RNA1509_34616, RNA1509_35220, RNA815_14475}
67. MligTC455_00832 699 14.56 Mlig455_006115, Mlig455_049816

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.548/0.02058
Region-enriched R3: 2.431/0.01183

LRIG3 1.681 - - - 0.951 - 0.730

Mlig455_006115 {REF} {Length: 231} {NoTransDecoderORF} {RNA1509_37269}

Mlig455_049816 {REF} {Length: 3502} {Pfam: Leucine rich repeat [PF13855.8, score=73.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=44.6]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=26.6]} {Human: ENSG00000139263, LRIG3, leucine rich repeats and immunoglobulin like domains 3, [Score=61.2, Expect=5e-09]} {Mouse: ENSMUSG00000020140, Lgr5, leucine rich repeat containing G protein coupled receptor 5, [Score=58.5, Expect=3e-08]} {Dmel: FBgn0028872, CG18095, [Score=59.3, Expect=1e-08]} {Celegans: WBGene00020649, sma-10, Leucine-rich repeats and immunoglobulin-like domains protein sma-10, [Score=53.9, Expect=5e-07]} {RNA1509_8817} {RNA1310_2409} {RNA815_590.1}
68. MligTC455_18654 497 10.36 Mlig455_032693

Neo: -

Age: -

PPME1 1.676 - - 0.717 0.959 - - Mlig455_032693 {REF} {Length: 2557} {TRANSSPLICED} {Pfam: Alpha/beta hydrolase family [PF12697.9, score=84.1]; alpha/beta hydrolase fold [PF00561.22, score=34.3]; Serine aminopeptidase, S33 [PF12146.10, score=30.6]; alpha/beta hydrolase fold [PF07859.15, score=20.5]; PGAP1-like protein [PF07819.15, score=19.9]} {Human: ENSG00000214517, PPME1, protein phosphatase methylesterase 1, [RH, Score=273, Expect=6e-87]} {Mouse: ENSMUSG00000030718, Ppme1, protein phosphatase methylesterase 1, [RH, Score=157, Expect=3e-43]} {Dmel: FBgn0035951, CG5068, [RH, Score=262, Expect=6e-83]} {Celegans: WBGene00007188, B0464.9, Probable protein phosphatase methylesterase 1, [RH, Score=147, Expect=4e-40]} {Smed: dd_Smed_v6_5813_0_1, dd_Smed_v6_5813_0_1, [RH, Score=291, Expect=1e-94]} {RNA1509_18678, RNA1509_50525} {RNA1310_14476, RNA1509_50525} {RNA1509_50525, RNA815_3742.1}
69. MligTC455_47804 2485 51.77 Mlig455_042589, Mlig455_042632

Neo: -

Age: -

Region-enriched R4: 1.074/0.01939

SMKR1 1.671 - - - 0.969 - 0.702

Mlig455_042589 {REF} {Length: 1673} {TRANSSPLICED} {Human: ENSG00000240204, SMKR1, small lysine rich protein 1, [RH, Score=53.5, Expect=1e-10]} {Dmel: FBgn0266615, CG45122, [RH, Score=41.2, Expect=6e-06]} {Smed: dd_Smed_v6_10158_0_1, dd_Smed_v6_10158_0_1, [RH, Score=43.9, Expect=4e-07]} {RNA1509_38498, RNA1509_57310} {RNA1310_41265, RNA1509_38498, RNA1509_57310} {RNA1509_38498, RNA1509_57310, RNA815_11227.2}

Mlig455_042632 {REF} {Length: 1583} {TRANSSPLICED} {Human: ENSG00000240204, SMKR1, small lysine rich protein 1, [RH, Score=54.3, Expect=5e-11]} {Dmel: FBgn0266615, CG45122, [Score=41.6, Expect=5e-06]} {Smed: dd_Smed_v6_10158_0_1, dd_Smed_v6_10158_0_1, [RH, Score=43.9, Expect=3e-07]} {RNA1509_11980, RNA1509_26819} {RNA1310_52333, RNA1509_11980, RNA1509_26819} {RNA1509_11980, RNA1509_26819, RNA815_11227.1}
70. MligTC455_31048 333 6.94 Mlig455_028972

Neo: -

Age: -

1.669 0.712 - - 0.957 - - Mlig455_028972 {REF} {Length: 2786} {RNA1509_41450} {RNA1310_29498} {RNA815_13329}
71. MligTC455_35377 667 13.89 Mlig455_011402

Neo: -

Age: -

YIPF5 1.666 - - 0.716 0.950 - - Mlig455_011402 {REF} {Length: 1977} {TRANSSPLICED} {Pfam: Yip1 domain [PF04893.19, score=39.3]} {Human: ENSG00000145817, YIPF5, Yip1 domain family member 5, [RH, Score=243, Expect=5e-80]} {Mouse: ENSMUSG00000024487, Yipf5, Yip1 domain family, member 5, [RH, Score=220, Expect=5e-71]; ENSMUSG00000029158, Yipf7, Yip1 domain family, member 7, [RH, Score=220, Expect=3e-71]} {Dmel: FBgn0032465, CG12404, [RH, Score=211, Expect=1e-67]} {Celegans: WBGene00009336, F32D8.14, [RH, Score=241, Expect=1e-79]} {Smed: dd_Smed_v6_4746_0_1, dd_Smed_v6_4746_0_1, [RH, Score=242, Expect=2e-80]} {RNA1509_31414, RNA1509_6683} {RNA1310_15036, RNA1509_31414} {RNA1509_31414, RNA815_6908.1}
72. MligTC455_37112 144 3 Mlig455_011711

Neo: -

Age: -

NEUROG1 1.665 - - - 0.954 0.711 - Mlig455_011711 {REF} {Length: 2595} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=56.3]} {Human: ENSG00000181965, NEUROG1, neurogenin 1, [RH, Score=82.8, Expect=5e-19]; ENSG00000178403, NEUROG2, neurogenin 2, [RH, Score=79.7, Expect=1e-17]} {Mouse: ENSMUSG00000048904, Neurog1, neurogenin 1, [RH, Score=82.0, Expect=7e-19]; ENSMUSG00000027967, Neurog2, neurogenin 2, [RH, Score=80.1, Expect=6e-18]} {Dmel: FBgn0015550, tap, target of Poxn, [RH, Score=85.5, Expect=2e-19]} {Celegans: WBGene00003595, ngn-1, NeuroGeNin, [RH, Score=70.1, Expect=5e-15]} {Smed: dd_Smed_v6_21717_0_1, dd_Smed_v6_21717_0_1, [Score=68.2, Expect=3e-14]} {RNA1509_25288} {RNA1310_19679} {RNA815_8549.1}
73. MligTC455_33974 520 10.84 Mlig455_026777

Neo: -

Age: -

CTNND2 1.659 - - 0.701 0.958 - - Mlig455_026777 {REF} {Length: 5315} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=61.0]; HEAT repeats [PF13646.8, score=21.5]} {Human: ENSG00000169862, CTNND2, catenin delta 2, [Score=297, Expect=8e-85]; ENSG00000144283, PKP4, plakophilin 4, [Score=286, Expect=1e-80]} {Mouse: ENSMUSG00000022240, Ctnnd2, catenin (cadherin associated protein), delta 2, [Score=295, Expect=4e-84]; ENSMUSG00000026991, Pkp4, plakophilin 4, [Score=286, Expect=8e-83]} {Dmel: FBgn0260799, p120ctn, Adherens junction protein p120, [Score=328, Expect=5e-99]} {Celegans: WBGene00002175, jac-1, Juxtamembrane domain-associated catenin, [Score=248, Expect=1e-68]} {Smed: dd_Smed_v6_6256_0_1, dd_Smed_v6_6256_0_1, [Score=239, Expect=1e-66]} {RNA1509_6533} {RNA1310_5357} {RNA815_401.1}
74. MligTC455_49324 968 20.16 Mlig455_062558

Neo: -

Age: -

Region-enriched R5: 1.520/0.00004

CASP8 1.659 - - - 0.701 - 0.958 Mlig455_062558 {REF} {Length: 2001} {TRANSSPLICED} {Pfam: Caspase domain [PF00656.24, score=75.4]} {Human: ENSG00000064012, CASP8, caspase 8, [Score=68.9, Expect=6e-12]} {Mouse: ENSMUSG00000031628, Casp3, caspase 3, [Score=62.0, Expect=2e-10]} {Dmel: FBgn0028381, Decay, Death executioner caspase related to Apopain/Yama, [Score=90.5, Expect=6e-20]} {Celegans: WBGene00000819, csp-1, Caspase A Caspase A subunit p16 Caspase A subunit p14, [Score=62.4, Expect=1e-10]} {Smed: dd_Smed_v6_9038_0_1, dd_Smed_v6_9038_0_1, [Score=77.4, Expect=3e-15]} {RNA1509_11703} {RNA1310_7431, RNA1509_11703} {RNA1509_11703, RNA815_4997}
75. MligTC455_26641 823 17.15 Mlig455_025147

Neo: -

Age: Up-Down-Down

PLXNB1 0.987 - - - 0.987 - - Mlig455_025147 {REF} {Length: 9317} {TRANSSPLICED} {Pfam: Plexin cytoplasmic RasGAP domain [PF08337.14, score=366.1]; Plexin repeat [PF01437.27, score=40.6]} {Human: ENSG00000164050, PLXNB1, plexin B1, [RH, Score=270, Expect=5e-72]} {Mouse: ENSMUSG00000029765, Plxna4, plexin A4, [Score=337, Expect=8e-93]} {Dmel: FBgn0025741, PlexA, Plexin A, [RH, Score=372, Expect=1e-103]} {Celegans: WBGene00004047, plx-1, PLeXin, [RH, Score=355, Expect=5e-99]} {Smed: dd_Smed_v6_11934_0_1, dd_Smed_v6_11934_0_1, [Score=122, Expect=2e-27]} {RNA1509_16282, RNA1509_16897, RNA1509_33615, RNA1509_40385} {RNA1310_431.1, RNA1509_16282, RNA1509_33615, RNA1509_40385} {RNA1509_16282, RNA1509_33615, RNA1509_40385, RNA815_663.1}
76. MligTC455_26642 818 17.05 Mlig455_063910

Neo: -

Age: -

0.987 - - - 0.987 - - Mlig455_063910 {REF} {Length: 1867} {NoTransDecoderORF} {RNA1509_16282} {RNA1310_23117.1} {RNA815_27706.1}
77. MligTC455_49646 739 15.39 Mlig455_067640

Neo: -

Age: -

MEF2D 0.984 - - - 0.984 - - Mlig455_067640 {REF} {Length: 5061} {TRANSSPLICED} {Pfam: SRF-type transcription factor (DNA-binding and dimerisation domain) [PF00319.20, score=87.0]} {Human: ENSG00000116604, MEF2D, myocyte enhancer factor 2D, [Score=171, Expect=2e-50]; ENSG00000213999, MEF2B, myocyte enhancer factor 2B, [Score=170, Expect=3e-51]; ENSG00000064489, BORCS8-MEF2B, BORCS8-MEF2B readthrough, [Score=170, Expect=3e-51]; ENSG00000068305, MEF2A, myocyte enhancer factor 2A, [Score=167, Expect=3e-49]; ENSG00000081189, MEF2C, myocyte enhancer factor 2C, [Score=166, Expect=1e-52]} {Mouse: ENSMUSG00000001419, Mef2d, myocyte enhancer factor 2D, [Score=171, Expect=1e-50]; ENSMUSG00000030557, Mef2a, myocyte enhancer factor 2A, [Score=167, Expect=2e-49]; ENSMUSG00000005583, Mef2c, myocyte enhancer factor 2C, [Score=166, Expect=4e-53]} {Dmel: FBgn0011656, Mef2, Myocyte enhancer factor 2, [Score=162, Expect=3e-47]} {Celegans: WBGene00003182, mef-2, Related to vertebrate MEF2 transcription factor, [Score=174, Expect=2e-53]} {Smed: dd_Smed_v6_6889_0_1, dd_Smed_v6_6889_0_1, [Score=152, Expect=4e-44]} {RNA1509_58067, RNA1509_8265} {RNA1310_21974.1, RNA1509_58067, RNA1509_8265} {RNA1509_58067, RNA1509_8265, RNA815_4359.2}
78. MligTC455_26386 624 13 Mlig455_020042

Neo: -

Age: logFC(26M/2M)=0.231

Region-enriched R5: 1.382/0.00337

0.983 - - - 0.983 - - Mlig455_020042 {REF} {Length: 4207} {TRANSSPLICED} {Smed: dd_Smed_v6_3465_0_1, dd_Smed_v6_3465_0_1, [RH, Score=112, Expect=6e-26]} {RNA1509_13462, RNA1509_58720} {RNA1310_9257, RNA1509_13462, RNA1509_58720} {RNA1509_13462, RNA1509_58720, RNA815_5213}
79. MligTC455_47236 631 13.14 Mlig455_011561

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.763

UBASH3B 0.983 - - - 0.983 - - Mlig455_011561 {REF} {Length: 5217} {Pfam: Histidine phosphatase superfamily (branch 1) [PF00300.24, score=51.3]} {Human: ENSG00000154127, UBASH3B, ubiquitin associated and SH3 domain containing B, [RH, Score=153, Expect=2e-38]} {Mouse: ENSMUSG00000032020, Ubash3b, ubiquitin associated and SH3 domain containing, B, [RH, Score=154, Expect=2e-39]} {Dmel: FBgn0039137, CG13604, [RH, Score=120, Expect=5e-28]} {Celegans: WBGene00020321, T07F12.1, [RH, Score=116, Expect=8e-29]} {Smed: dd_Smed_v6_12024_0_1, dd_Smed_v6_12024_0_1, [RH, Score=162, Expect=5e-42]} {RNA1509_10245, RNA1509_27327} {RNA1310_4087.1, RNA1509_27327} {RNA1509_27327, RNA815_2334.1}
80. MligTC455_21393 2300 47.91 Mlig455_036038, Mlig455_036129

Neo: -

Age: -

ALOX12B 0.982 - - - 0.982 - -

Mlig455_036038 {REF} {Length: 3252} {TRANSSPLICED} {Pfam: Lipoxygenase [PF00305.21, score=143.5]; PLAT/LH2 domain [PF01477.25, score=34.3]} {Human: ENSG00000179477, ALOX12B, arachidonate 12-lipoxygenase, 12R type, [RH, Score=174, Expect=2e-45]; ENSG00000275565, ALOX5, arachidonate 5-lipoxygenase, [RH, Score=174, Expect=1e-45]; ENSG00000012779, ALOX5, arachidonate 5-lipoxygenase, [RH, Score=174, Expect=1e-45]} {Mouse: ENSMUSG00000020891, Alox8, arachidonate 8-lipoxygenase, [RH, Score=173, Expect=2e-45]; ENSMUSG00000032807, Alox12b, arachidonate 12-lipoxygenase, 12R type, [RH, Score=172, Expect=4e-45]} {Smed: dd_Smed_v6_7204_0_1, dd_Smed_v6_7204_0_1, [RH, Score=409, Expect=2e-137]} {RNA1509_5119} {RNA1310_6654.2} {RNA815_2121.1}

Mlig455_036129 {REF} {Length: 3222} {TRANSSPLICED} {Pfam: Lipoxygenase [PF00305.21, score=143.5]; PLAT/LH2 domain [PF01477.25, score=34.3]} {Human: ENSG00000179477, ALOX12B, arachidonate 12-lipoxygenase, 12R type, [RH, Score=174, Expect=2e-45]; ENSG00000275565, ALOX5, arachidonate 5-lipoxygenase, [RH, Score=174, Expect=1e-45]; ENSG00000012779, ALOX5, arachidonate 5-lipoxygenase, [RH, Score=174, Expect=1e-45]} {Mouse: ENSMUSG00000020891, Alox8, arachidonate 8-lipoxygenase, [RH, Score=173, Expect=2e-45]; ENSMUSG00000032807, Alox12b, arachidonate 12-lipoxygenase, 12R type, [RH, Score=172, Expect=4e-45]} {Smed: dd_Smed_v6_7204_0_1, dd_Smed_v6_7204_0_1, [RH, Score=409, Expect=2e-137]} {RNA1509_42264, RNA1509_42556, RNA1509_5119} {RNA1310_6654.2, RNA1509_42264, RNA1509_42556} {RNA1509_42264, RNA1509_42556, RNA815_2121.1}
81. MligTC455_33224 583 12.14 Mlig455_062467

Neo: -

Age: -

PTPRR 0.981 - - - 0.981 - - Mlig455_062467 {REF} {Length: 2901} {TRANSSPLICED} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=215.2]; Tyrosine phosphatase family [PF13350.8, score=20.4]; Adenovirus E3 region protein CR2 [PF02439.17, score=18.4]} {Human: ENSG00000153233, PTPRR, protein tyrosine phosphatase, receptor type R, [RH, Score=233, Expect=4e-71]} {Mouse: ENSMUSG00000020151, Ptprr, protein tyrosine phosphatase, receptor type, R, [RH, Score=230, Expect=2e-69]} {Dmel: FBgn0004369, Ptp99A, Protein tyrosine phosphatase 99A, [Score=151, Expect=4e-39]} {Celegans: WBGene00004215, ptp-3, Tyrosine-protein phosphatase Lar-like, [Score=152, Expect=1e-39]} {Smed: dd_Smed_v6_8755_0_1, dd_Smed_v6_8755_0_1, [RH, Score=253, Expect=2e-78]} {RNA1509_58461} {RNA1310_7060.2} {RNA815_5407.1}
82. MligTC455_35404 997 20.77 Mlig455_000846

Neo: -

Age: -

MAPK8IP3 0.981 - - - 0.981 - - Mlig455_000846 {REF} {Length: 3028} {Pfam: WD40 repeated domain [PF19056.2, score=111.4]; JNK-interacting protein leucine zipper II [PF16471.7, score=93.6]} {Human: ENSG00000138834, MAPK8IP3, mitogen-activated protein kinase 8 interacting protein 3, [RH, Score=322, Expect=1e-93]; ENSG00000008294, SPAG9, sperm associated antigen 9, [RH, Score=313, Expect=2e-90]} {Mouse: ENSMUSG00000024163, Mapk8ip3, mitogen-activated protein kinase 8 interacting protein 3, [RH, Score=515, Expect=6e-165]} {Dmel: FBgn0024187, syd, sunday driver, [RH, Score=491, Expect=8e-157]} {Celegans: WBGene00006755, unc-16, JNK-interacting protein, [RH, Score=449, Expect=2e-141]} {Smed: dd_Smed_v6_3798_0_2, dd_Smed_v6_3798_0_2, [RH, Score=320, Expect=9e-95]} {RNA1509_5595} {RNA1310_1825.1} {RNA815_753.1}
83. MligTC455_35405 975 20.3 Mlig455_057162

Neo: -

Age: -

0.981 - - - 0.981 - - Mlig455_057162 {REF} {Length: 816} {NoTransDecoderORF} {RNA1509_25928} {RNA1310_1825.1} {RNA815_753.1}
84. MligTC455_45831 2114 44.05 Mlig455_043513

Neo: -

Age: -

Region-enriched R4: 1.048/0.00075

ISCA1 0.981 - - - 0.981 - - Mlig455_043513 {REF} {Length: 1208} {TRANSSPLICED} {Pfam: Iron-sulphur cluster biosynthesis [PF01521.22, score=70.9]} {Human: ENSG00000135070, ISCA1, iron-sulfur cluster assembly 1, [RH, Score=149, Expect=1e-46]} {Mouse: ENSMUSG00000078139, AK157302, cDNA sequence AK157302, [RH, Score=149, Expect=1e-46]; ENSMUSG00000044792, Isca1, iron-sulfur cluster assembly 1, [RH, Score=147, Expect=4e-46]} {Dmel: FBgn0026666, MagR, Magnetic receptor, [RH, Score=155, Expect=2e-49]} {Celegans: WBGene00012666, Y39B6A.3, [RH, Score=156, Expect=1e-49]} {Smed: dd_Smed_v6_4788_0_1, dd_Smed_v6_4788_0_1, [RH, Score=146, Expect=9e-46]} {RNA1509_45251} {RNA1310_8034.1, RNA1509_45251} {RNA1509_45251, RNA815_12442}
85. MligTC455_25874 465 9.69 Mlig455_002801

Neo: -

Age: -

PPP6R3 0.98 - - - 0.980 - - Mlig455_002801 {REF} {Length: 5109} {TRANSSPLICED} {Pfam: SIT4 phosphatase-associated protein [PF04499.17, score=152.6]} {Human: ENSG00000110075, PPP6R3, protein phosphatase 6 regulatory subunit 3, [RH, Score=326, Expect=3e-97]; ENSG00000100239, PPP6R2, protein phosphatase 6 regulatory subunit 2, [RH, Score=312, Expect=1e-91]} {Mouse: ENSMUSG00000024908, Ppp6r3, protein phosphatase 6, regulatory subunit 3, [RH, Score=327, Expect=7e-98]} {Dmel: FBgn0035688, CG10289, [RH, Score=206, Expect=1e-54]} {Celegans: WBGene00008166, saps-1, SAPS (Phosphatase associated) domain protein, [RH, Score=73.6, Expect=4e-13]} {Smed: dd_Smed_v6_2215_0_1, dd_Smed_v6_2215_0_1, [RH, Score=125, Expect=5e-29]} {RNA1509_59231, RNA1509_6659} {RNA1310_4346.1, RNA1509_59231} {RNA1509_59231, RNA815_12593}
86. MligTC455_18862 978 20.37 Mlig455_002729

Neo: -

Age: -

Region-enriched R2: 2.218/0.00186

DNAH7 0.979 - - - 0.979 - - Mlig455_002729 {REF} {Length: 7261} {Pfam: P-loop containing dynein motor region D4 [PF12780.9, score=329.5]; ATP-binding dynein motor region [PF12781.9, score=255.0]; Microtubule-binding stalk of dynein motor [PF12777.9, score=186.0]; AAA+ lid domain [PF17857.3, score=75.3]} {Human: ENSG00000118997, DNAH7, dynein axonemal heavy chain 7, [Score=1660, Expect=0.0]} {Mouse: ENSMUSG00000041144, Dnah7b, dynein, axonemal, heavy chain 7B, [Score=1672, Expect=0.0]; ENSMUSG00000101337, Dnah7c, dynein, axonemal, heavy chain 7C, [Score=1670, Expect=0.0]; ENSMUSG00000096141, Dnah7a, dynein, axonemal, heavy chain 7A, [Score=1665, Expect=0.0]} {Dmel: FBgn0013810, Dhc36C, Dynein heavy chain at 36C, [Score=1410, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=437, Expect=3e-129]} {Smed: dd_Smed_v6_5350_0_1, dd_Smed_v6_5350_0_1, [Score=1761, Expect=0.0]} {RNA1509_18785, RNA1509_228} {RNA1310_355.1, RNA1509_18785} {RNA1509_18785, RNA815_28.1}
87. MligTC455_18871 1004 20.91 Mlig455_002731, Mlig455_063346

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=-1.287

Region-enriched R2: 2.201/0.00053

DNAH7 0.979 - - - 0.979 - -

Mlig455_002731 {REF} {Length: 838} {TRANSSPLICED} {Human: ENSG00000118997, DNAH7, dynein axonemal heavy chain 7, [Score=144, Expect=1e-39]} {Mouse: ENSMUSG00000041144, Dnah7b, dynein, axonemal, heavy chain 7B, [Score=142, Expect=4e-38]; ENSMUSG00000096141, Dnah7a, dynein, axonemal, heavy chain 7A, [Score=137, Expect=2e-36]; ENSMUSG00000101337, Dnah7c, dynein, axonemal, heavy chain 7C, [Score=135, Expect=6e-36]} {Dmel: FBgn0013810, Dhc36C, Dynein heavy chain at 36C, [Score=78.2, Expect=3e-16]} {Smed: dd_Smed_v6_13792_0_1, dd_Smed_v6_13792_0_1, [Score=236, Expect=2e-71]} {RNA1509_228} {RNA1310_71} {RNA815_34.1}

Mlig455_063346 {REF} {Length: 12883} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=514.7]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=491.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=396.1]; P-loop containing dynein motor region D4 [PF12780.9, score=361.9]; ATP-binding dynein motor region [PF12781.9, score=323.9]; P-loop containing dynein motor region [PF12775.9, score=283.4]; Dynein heavy chain AAA lid domain [PF18198.3, score=202.8]; Microtubule-binding stalk of dynein motor [PF12777.9, score=186.0]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=158.5]; Dynein heavy chain AAA lid domain [PF17852.3, score=117.3]; AAA+ lid domain [PF17857.3, score=76.6]; AAA domain (dynein-related subfamily) [PF07728.16, score=72.3]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=32.8]; AAA ATPase domain [PF13191.8, score=24.9]; AAA domain [PF13401.8, score=23.3]} {Human: ENSG00000118997, DNAH7, dynein axonemal heavy chain 7, [RH, Score=5532, Expect=0.0]} {Mouse: ENSMUSG00000101337, Dnah7c, dynein, axonemal, heavy chain 7C, [RH, Score=5525, Expect=0.0]; ENSMUSG00000041144, Dnah7b, dynein, axonemal, heavy chain 7B, [RH, Score=5516, Expect=0.0]; ENSMUSG00000096141, Dnah7a, dynein, axonemal, heavy chain 7A, [RH, Score=5500, Expect=0.0]} {Dmel: FBgn0013810, Dhc36C, Dynein heavy chain at 36C, [RH, Score=4478, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=728, Expect=0.0]} {Smed: dd_Smed_v6_5350_0_1, dd_Smed_v6_5350_0_1, [RH, Score=4420, Expect=0.0]} {RNA1509_11080, RNA1509_21150, RNA1509_21155, RNA1509_228, RNA1509_28894} {RNA1310_71, RNA1509_11080, RNA1509_21150, RNA1509_21155, RNA1509_228, RNA1509_28894} {RNA1509_11080, RNA1509_21150, RNA1509_21155, RNA1509_228, RNA1509_28894, RNA815_248}
88. MligTC455_25399 322 6.71 Mlig455_044279

Neo: -

Age: -

0.979 - - - 0.979 - - Mlig455_044279 {REF} {Length: 2629} {TRANSSPLICED} {RNA1509_18232} {RNA1310_43277} {RNA815_27069}
89. MligTC455_31161 617 12.85 Mlig455_022730

Neo: -

Age: Up-Down-Down

MLXIPL 0.979 - - - 0.979 - - Mlig455_022730 {REF} {Length: 7247} {TRANSSPLICED} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=38.2]} {Human: ENSG00000009950, MLXIPL, MLX interacting protein like, [RH, Score=163, Expect=1e-40]} {Mouse: ENSMUSG00000005373, Mlxipl, MLX interacting protein-like, [RH, Score=165, Expect=2e-41]} {Dmel: FBgn0032940, Mondo, [RH, Score=145, Expect=4e-35]} {Celegans: WBGene00003378, mml-1, Protein WBSCR14 homolog, [RH, Score=135, Expect=3e-32]} {Smed: dd_Smed_v6_9226_0_1, dd_Smed_v6_9226_0_1, [RH, Score=144, Expect=3e-35]} {RNA1509_10185, RNA1509_53815, RNA1509_60070} {RNA1310_3768, RNA1509_10185, RNA1509_53815, RNA1509_60070} {RNA1509_10185, RNA1509_53815, RNA1509_60070, RNA815_3226}
90. MligTC455_31802 524 10.92 Mlig455_055004

Neo: -

Age: logFC(26M/2M)=-0.336

EFCAB6 0.979 - - - 0.979 - - Mlig455_055004 {REF} {Length: 4093} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=77.2]; EF-hand domain pair [PF13833.8, score=63.0]; EF-hand domain [PF08976.13, score=57.8]; EF-hand domain [PF13405.8, score=55.2]; EF hand [PF00036.34, score=52.6]; Family of unknown function (DUF5580) [PF17743.3, score=28.1]; EF-hand domain [PF14658.8, score=27.3]; EF hand [PF13202.8, score=22.4]} {Human: ENSG00000186976, EFCAB6, EF-hand calcium binding domain 6, [Score=79.7, Expect=2e-14]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=75.1, Expect=4e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=49.3, Expect=2e-06]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=50.8, Expect=3e-07]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=154, Expect=2e-39]} {RNA1509_11692} {RNA1310_3239.1} {RNA815_3758}
91. MligTC455_17737 522 10.87 Mlig455_005002

Neo: -

Age: -

0.978 - - - 0.978 - - Mlig455_005002 {REF} {Length: 982} {NoTransDecoderORF} {RNA1310_1426.1} {RNA815_30413}
92. MligTC455_18870 1001 20.86 Mlig455_002445, Mlig455_002730

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.707

Region-enriched R2: 2.415/0.00019

DNAH7 0.978 - - - 0.978 - -

Mlig455_002445 {REF} {Length: 13764} {TRANSSPLICED} {Pfam: Dynein heavy chain C-terminal domain [PF18199.3, score=397.0]; P-loop containing dynein motor region D4 [PF12780.9, score=362.4]; ATP-binding dynein motor region [PF12781.9, score=318.6]; P-loop containing dynein motor region [PF12775.9, score=280.4]; Dynein heavy chain AAA lid domain [PF18198.3, score=203.4]; Microtubule-binding stalk of dynein motor [PF12777.9, score=185.3]; Dynein heavy chain AAA lid domain [PF17852.3, score=117.6]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=102.5]; AAA+ lid domain [PF17857.3, score=77.9]; AAA domain (dynein-related subfamily) [PF07728.16, score=51.0]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=20.5]; AAA domain [PF13401.8, score=19.5]} {Human: ENSG00000118997, DNAH7, dynein axonemal heavy chain 7, [Score=3468, Expect=0.0]} {Mouse: ENSMUSG00000101337, Dnah7c, dynein, axonemal, heavy chain 7C, [Score=3486, Expect=0.0]; ENSMUSG00000041144, Dnah7b, dynein, axonemal, heavy chain 7B, [Score=3474, Expect=0.0]; ENSMUSG00000096141, Dnah7a, dynein, axonemal, heavy chain 7A, [Score=3472, Expect=0.0]} {Dmel: FBgn0013810, Dhc36C, Dynein heavy chain at 36C, [Score=2909, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=700, Expect=0.0]} {Smed: dd_Smed_v6_5350_0_1, dd_Smed_v6_5350_0_1, [Score=3768, Expect=0.0]} {RNA1509_228} {RNA1310_71} {RNA815_248}

Mlig455_002730 {REF} {Length: 420} {Pfam: Dynein heavy chain, N-terminal region 2 [PF08393.15, score=27.2]} {Human: ENSG00000118997, DNAH7, dynein axonemal heavy chain 7, [Score=98.2, Expect=1e-24]} {Mouse: ENSMUSG00000096141, Dnah7a, dynein, axonemal, heavy chain 7A, [Score=100, Expect=2e-25]; ENSMUSG00000041144, Dnah7b, dynein, axonemal, heavy chain 7B, [Score=98.6, Expect=8e-25]; ENSMUSG00000101337, Dnah7c, dynein, axonemal, heavy chain 7C, [Score=97.8, Expect=2e-24]} {Smed: dd_Smed_v6_13792_0_2, dd_Smed_v6_13792_0_2, [Score=102, Expect=2e-26]} {RNA1509_228} {RNA1310_71} {RNA815_34.1}
93. MligTC455_31803 504 10.5 Mlig455_059772

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.440

EFCAB6 0.978 - - - 0.978 - - Mlig455_059772 {REF} {Length: 3998} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=86.2]; EF-hand domain [PF08976.13, score=70.4]; EF-hand domain pair [PF13833.8, score=62.2]; EF-hand domain [PF13405.8, score=57.9]; EF hand [PF00036.34, score=53.9]; EF-hand domain [PF14658.8, score=35.9]; Family of unknown function (DUF5580) [PF17743.3, score=28.0]; EF hand [PF13202.8, score=22.4]} {Human: ENSG00000186976, EFCAB6, EF-hand calcium binding domain 6, [Score=89.7, Expect=2e-17]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=76.3, Expect=2e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=49.3, Expect=2e-06]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=50.8, Expect=3e-07]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=154, Expect=9e-40]} {RNA1509_7148} {RNA1310_3069.1, RNA1509_7148} {RNA1509_7148, RNA815_3758}
94. MligTC455_49005 642 13.37 Mlig455_043634

Neo: -

Age: -

CCDC180 0.978 - - - 0.978 - - Mlig455_043634 {REF} {Length: 3450} {Pfam: Domain of unknown function (DUF4456) [PF14644.8, score=137.1]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [Score=160, Expect=2e-41]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [Score=110, Expect=3e-25]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [Score=166, Expect=4e-44]} {RNA1509_8832} {RNA1310_898.2} {RNA815_8511}
95. MligTC455_06930 595 12.39 Mlig455_036374

Neo: -

Age: -

GNA13 0.977 - - - 0.977 - - Mlig455_036374 {REF} {Length: 4785} {TRANSSPLICED} {Pfam: G-protein alpha subunit [PF00503.22, score=205.8]; ADP-ribosylation factor family [PF00025.23, score=32.3]} {Human: ENSG00000120063, GNA13, G protein subunit alpha 13, [Score=182, Expect=4e-53]} {Mouse: ENSMUSG00000020611, Gna13, guanine nucleotide binding protein, alpha 13, [Score=184, Expect=1e-53]} {Dmel: FBgn0000384, cta, concertina, [Score=172, Expect=1e-48]} {Celegans: WBGene00001196, egl-30, EGL-30; Heterotrimeric G protein alpha subunit, [Score=169, Expect=1e-48]} {Smed: dd_Smed_v6_2931_0_1, dd_Smed_v6_2931_0_1, [Score=191, Expect=2e-56]} {RNA1509_5056} {RNA1310_20481, RNA1509_5056} {RNA1509_5056, RNA815_8404.1}
96. MligTC455_19818 455 9.49 Mlig455_030794, Mlig455_037967

Neo: -

Age: Down-Up-Down

0.977 - - - 0.977 - -

Mlig455_030794 {REF} {Length: 582} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45712} {RNA1310_64066} {RNA815_23034.1}

Mlig455_037967 {REF} {Length: 221} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45712} {RNA1310_64066} {RNA815_23034.1}
97. MligTC455_34468 267 5.57 Mlig455_066223

Neo: -

Age: -

Region-enriched R3: 2.267/0.04085

SLK 0.977 - - - 0.977 - - Mlig455_066223 {REF} {Length: 3497} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=192.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=159.4]; Polo kinase kinase [PF12474.10, score=26.1]} {Human: ENSG00000065613, SLK, STE20 like kinase, [RH, Score=327, Expect=1e-95]} {Mouse: ENSMUSG00000025060, Slk, STE20-like kinase, [RH, Score=327, Expect=1e-95]} {Dmel: FBgn0035001, Slik, Sterile20-like kinase, [Score=306, Expect=5e-88]} {Celegans: WBGene00007287, gck-4, Germinal Center Kinase family, [Score=261, Expect=7e-73]} {Smed: dd_Smed_v6_5720_0_1, dd_Smed_v6_5720_0_1, [Score=318, Expect=8e-95]} {RNA1509_17021} {RNA1310_7112, RNA1509_17021} {RNA1509_17021, RNA815_5237}
98. MligTC455_38125 1068 22.25 Mlig455_039356

Neo: -

Age: logFC(26M/2M)=0.307

SRPRA 0.977 - - - - - 0.977 Mlig455_039356 {REF} {Length: 3711} {TRANSSPLICED} {Pfam: Signal recognition particle, alpha subunit, N-terminal [PF04086.15, score=193.2]; SRP54-type protein, GTPase domain [PF00448.24, score=159.1]; SRP54-type protein, helical bundle domain [PF02881.21, score=32.5]; AAA ATPase domain [PF13191.8, score=25.2]; Methylmalonyl Co-A mutase-associated GTPase MeaB [PF03308.18, score=21.9]; CobQ/CobB/MinD/ParA nucleotide binding domain [PF01656.25, score=19.7]} {Human: ENSG00000182934, SRPRA, SRP receptor subunit alpha, [RH, Score=638, Expect=0.0]} {Mouse: ENSMUSG00000032042, Srpr, signal recognition particle receptor ('docking protein'), [Score=650, Expect=0.0]} {Dmel: FBgn0010391, Gtp-bp, GTP-binding protein, [Score=609, Expect=0.0]} {Celegans: WBGene00009521, F38A1.8, [RH, Score=524, Expect=2e-179]} {Smed: dd_Smed_v6_1375_0_1, dd_Smed_v6_1375_0_1, [RH, Score=548, Expect=0.0]} {RNA1509_10861, RNA1509_7658, RNA1509_9355} {RNA1310_2507.1, RNA1509_10861, RNA1509_7658, RNA1509_9355} {RNA1509_10861, RNA1509_7658, RNA1509_9355, RNA815_944}
99. MligTC455_45520 1265 26.35 Mlig455_029387

Neo: -

Age: logFC(26M/2M)=0.232

ANKRD50 0.977 - - - - - 0.977 Mlig455_029387 {REF} {Length: 3441} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=219.7]; Protein kinase domain [PF00069.27, score=193.4]; Ankyrin repeats (many copies) [PF13637.8, score=186.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=150.0]; Ankyrin repeat [PF13606.8, score=135.1]; Ankyrin repeats (many copies) [PF13857.8, score=124.9]; Ankyrin repeat [PF00023.32, score=103.1]; ABC1 atypical kinase-like domain [PF03109.18, score=30.9]; Kinase-like [PF14531.8, score=30.6]; Fungal protein kinase [PF17667.3, score=27.6]; Phosphotransferase enzyme family [PF01636.25, score=20.1]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=174, Expect=5e-44]; ENSG00000151150, ANK3, ankyrin 3, [Score=171, Expect=8e-43]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=174, Expect=3e-44]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=170, Expect=9e-43]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=171, Expect=3e-43]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=159, Expect=1e-39]} {Smed: dd_Smed_v6_11663_0_4, dd_Smed_v6_11663_0_4, [Score=202, Expect=1e-54]} {RNA1509_19302, RNA1509_37971, RNA1509_4407, RNA1509_58769} {RNA1310_2580.1, RNA1509_19302, RNA1509_37971, RNA1509_4407, RNA1509_58769} {RNA1509_19302, RNA1509_37971, RNA1509_4407, RNA1509_58769, RNA815_1154.1}
100. MligTC455_45716 425 8.84 Mlig455_035333

Neo: -

Age: Down-Down-Up

0.977 - - - 0.977 - - Mlig455_035333 {REF} {Length: 2536} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=24.2]; Ankyrin repeats (many copies) [PF13857.8, score=24.0]; Ankyrin repeat [PF13606.8, score=20.9]} {RNA1509_6394} {RNA1310_30583.1} {RNA815_19682}

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