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Results for MligTC455_09409

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_09409 58 1.20 Mlig455_022373, Mlig455_022461, Mlig455_069874

Neo: Int S/G2/M

Age: -

Region-enriched R4: 7.200/0.00000

Regeneration-downregulated R4: -4.921

Regeneration-depleted R4: -4.921

Mlig455_022373 {REF} {Length: 616} {Pfam: WSC domain [PF01822.21, score=23.5]; PAN domain [PF00024.28, score=21.1]} {RNA1509_30295} {RNA1310_66153} {RNA815_34112}

Mlig455_022461 {REF} {Length: 599} {Pfam: PAN domain [PF00024.28, score=19.0]} {RNA1509_30295} {RNA1310_66153} {RNA815_34112}

Mlig455_069874 {REF} {Length: 525} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_53783} {RNA1310_66153} {RNA815_34112}

Cumulative graph for MligTC455_09409

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 6.837 1.571 0.01747 0.36850
RegionR2 -1.05 1.571 0.92105 1.00000
RegionR3 -1.469 1.571 0.95080 1.00000
RegionR4 7.2 1.571 0.00000 0.00000
RegionR5 -1.16 1.571 0.93092 1.00000
RegionR6 -0.14 1.571 0.75928 1.00000
RegionR7 -5.08 1.571 1.00000 1.00000
RegionR8 -5.14 1.571 0.99990 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.125 1.571 0.20317 0.94307
RegenerationR2 1.12 1.571 0.18122 0.62396
RegenerationR3 -3.486 1.571 0.02093 0.26360
RegenerationR4 -4.921 1.571 0.00000 0.00070 Specific for R4: -4.921
RegenerationR5 -2.722 1.571 0.04969 0.35982
RegenerationR6 -1.018 1.571 0.44872 0.76954
RegenerationBL -0.049 1.571 0.99988 1.00000
RegenerationTP 4.551 1.571 0.07693 0.44322


Genes with expression patterns similar to MligTC455_09409

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_09409 58 1.2 Mlig455_022373, Mlig455_022461, Mlig455_069874

Neo: Int S/G2/M

Age: -

Region-enriched R4: 7.200/0.00000

Regeneration-downregulated R4: -4.921

Regeneration-depleted R4: -4.921

5 1.000 1.000 1.000 1.000 - 1.000

Mlig455_022373 {REF} {Length: 616} {Pfam: WSC domain [PF01822.21, score=23.5]; PAN domain [PF00024.28, score=21.1]} {RNA1509_30295} {RNA1310_66153} {RNA815_34112}

Mlig455_022461 {REF} {Length: 599} {Pfam: PAN domain [PF00024.28, score=19.0]} {RNA1509_30295} {RNA1310_66153} {RNA815_34112}

Mlig455_069874 {REF} {Length: 525} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_53783} {RNA1310_66153} {RNA815_34112}
2. MligTC455_48714 132 2.74 Mlig455_037041

Neo: -

Age: -

Region-enriched R2: 4.531/0.00493

1.937 - - - 0.974 - 0.963 Mlig455_037041 {REF} {Length: 1099} {RNA1509_35038} {RNA1310_72135} {RNA815_37404}
3. MligTC455_48713 380 7.92 Mlig455_009259, Mlig455_009268

Neo: -

Age: Down-Up-Down

Region-specific R2: 6.962

Region-enriched R2: 4.845/0.00046
Region-enriched R6: 3.343/0.03198

1.931 - - - 0.970 - 0.961

Mlig455_009259 {REF} {Length: 654} {RNA1509_35038} {RNA1310_72135} {RNA815_37404}

Mlig455_009268 {REF} {Length: 546} {RNA1509_35038} {RNA1310_72135, RNA1509_35038} {RNA1509_35038, RNA815_37404}
4. MligTC455_43962 120 2.5 Mlig455_020783

Neo: -

Age: -

TRAF5 1.909 - - - 0.936 - 0.973 Mlig455_020783 {REF} {Length: 3242} {Human: ENSG00000082512, TRAF5, TNF receptor associated factor 5, [Score=90.5, Expect=3e-20]} {Mouse: ENSMUSG00000026637, Traf5, TNF receptor-associated factor 5, [Score=88.6, Expect=1e-20]; ENSMUSG00000111385, Traf5, TNF receptor-associated factor 5, [Score=88.6, Expect=1e-20]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=70.9, Expect=6e-14]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [Score=99.0, Expect=8e-24]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [Score=132, Expect=8e-36]} {RNA1310_36792.1} {RNA815_40908}
5. MligTC455_24064 359 7.48 Mlig455_048183

Neo: -

Age: -

SNAP25 1.883 - - - 0.928 - 0.955 Mlig455_048183 {REF} {Length: 1315} {Pfam: SNAP-25 family [PF00835.21, score=41.5]} {Human: ENSG00000132639, SNAP25, synaptosome associated protein 25, [Score=219, Expect=7e-72]} {Mouse: ENSMUSG00000027273, Snap25, synaptosomal-associated protein 25, [Score=219, Expect=5e-72]} {Dmel: FBgn0266720, Snap24, Synaptosomal-associated protein 24kDa, [RH, Score=228, Expect=1e-75]} {Celegans: WBGene00004364, ric-4, Synaptosomal-associated protein, [RH, Score=257, Expect=2e-87]} {Smed: dd_Smed_v6_3977_0_1, dd_Smed_v6_3977_0_1, [RH, Score=282, Expect=2e-97]} {RNA1509_8624} {RNA1310_24253} {RNA815_10439}
6. MligTC455_12255 87 1.82 Mlig455_042299

Neo: -

Age: Down-Up-Down

Region-enriched R8: 4.103/0.00190
Region-enriched R7: 3.191/0.00610

1.881 - - - 0.928 - 0.953 Mlig455_042299 {REF} {Length: 2190} {Smed: dd_Smed_v6_18803_0_1, dd_Smed_v6_18803_0_1, [Score=244, Expect=3e-75]} {RNA1310_26226} {RNA815_49309}
7. MligTC455_05098 127 2.65 Mlig455_009525, Mlig455_009531

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.095/0.01821

KCNH7 1.869 - - - 0.952 - 0.917

Mlig455_009525 {REF} {Length: 2109} {Pfam: Ion transport protein [PF00520.33, score=111.8]; Ion channel [PF07885.18, score=46.1]; Cyclic nucleotide-binding domain [PF00027.31, score=36.3]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=29.8]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=528, Expect=4e-176]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=509, Expect=2e-170]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=505, Expect=9e-167]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=527, Expect=4e-175]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=510, Expect=3e-171]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=504, Expect=9e-167]} {Dmel: FBgn0003353, sei, seizure, [Score=507, Expect=2e-171]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=496, Expect=1e-169]} {Smed: dd_Smed_v6_12978_0_1, dd_Smed_v6_12978_0_1, [Score=608, Expect=0.0]} {RNA1509_56964} {RNA1310_41939} {RNA815_5858.1}

Mlig455_009531 {REF} {Length: 3631} {Pfam: Ion transport protein [PF00520.33, score=110.4]; Ion channel [PF07885.18, score=45.2]; Cyclic nucleotide-binding domain [PF00027.31, score=43.3]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=619, Expect=0.0]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=597, Expect=0.0]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=596, Expect=0.0]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=617, Expect=0.0]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=602, Expect=0.0]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=596, Expect=0.0]} {Dmel: FBgn0003353, sei, seizure, [Score=591, Expect=0.0]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=579, Expect=0.0]} {Smed: dd_Smed_v6_12978_0_4, dd_Smed_v6_12978_0_4, [RH, Score=716, Expect=0.0]} {RNA1509_56964} {RNA1310_23186, RNA1509_56964} {RNA1509_56964, RNA815_5858.2}
8. MligTC455_13424 708 14.75 Mlig455_044367

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.089

Region-enriched R7: 4.024/0.00101

1.863 - - - 0.900 - 0.963 Mlig455_044367 {REF} {Length: 633} {RNA1509_34081, RNA1509_52094} {RNA1310_75122.1, RNA1509_34081, RNA1509_52094} {RNA1509_34081, RNA1509_52094, RNA815_57840}
9. MligTC455_41742 48 1 Mlig455_002367, Mlig455_044569

Neo: -

Age: -

1.853 - - 0.893 - - 0.960

Mlig455_002367 {REF} {Length: 416} {RNA1310_97120} {RNA815_50408}

Mlig455_044569 {REF} {Length: 416} {RNA1310_97120} {RNA815_50408}
10. MligTC455_17579 76 1.58 Mlig455_042836, Mlig455_045854, Mlig455_045870

Neo: -

Age: -

RNF217 1.851 - - - 0.891 - 0.960

Mlig455_042836 {REF} {Length: 3004} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=75.3]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=83.6, Expect=5e-16]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=83.2, Expect=4e-16]} {Dmel: FBgn0036082, CG12362, [Score=57.0, Expect=4e-08]} {Celegans: WBGene00020462, T12E12.1, Potential E3 ubiquitin-protein ligase ariadne-2, [Score=57.0, Expect=4e-08]} {Smed: dd_Smed_v6_7986_0_1, dd_Smed_v6_7986_0_1, [Score=61.2, Expect=1e-09]} {RNA1310_42946} {RNA815_24345}

Mlig455_045854 {REF} {Length: 3004} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=74.7]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=83.2, Expect=5e-16]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=83.2, Expect=4e-16]} {Dmel: FBgn0036082, CG12362, [Score=57.4, Expect=3e-08]} {Celegans: WBGene00020462, T12E12.1, Potential E3 ubiquitin-protein ligase ariadne-2, [Score=57.8, Expect=2e-08]} {Smed: dd_Smed_v6_7986_0_1, dd_Smed_v6_7986_0_1, [Score=61.2, Expect=1e-09]} {RNA1310_42946} {RNA815_24345}

Mlig455_045870 {REF} {Length: 3004} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=74.9]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=83.2, Expect=5e-16]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=83.2, Expect=4e-16]} {Dmel: FBgn0036082, CG12362, [Score=57.4, Expect=3e-08]} {Celegans: WBGene00020462, T12E12.1, Potential E3 ubiquitin-protein ligase ariadne-2, [Score=57.0, Expect=4e-08]} {Smed: dd_Smed_v6_7986_0_1, dd_Smed_v6_7986_0_1, [Score=61.2, Expect=1e-09]} {RNA1310_42946} {RNA815_24345}
11. MligTC455_35739 91 1.9 Mlig455_050779

Neo: -

Age: Up-Down-Down

ADGRL2 1.849 - - - 0.957 - 0.892 Mlig455_050779 {REF} {Length: 4277} {Pfam: 7 transmembrane receptor (Secretin family) [PF00002.26, score=110.1]; Pentaxin family [PF00354.19, score=43.4]; Hormone receptor domain [PF02793.24, score=35.9]; Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=33.0]; GPCR-Autoproteolysis INducing (GAIN) domain [PF16489.7, score=20.5]; Myc amino-terminal region [PF01056.20, score=18.8]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [RH, Score=140, Expect=5e-33]; ENSG00000072071, ADGRL1, adhesion G protein-coupled receptor L1, [RH, Score=139, Expect=2e-32]; ENSG00000150471, ADGRL3, adhesion G protein-coupled receptor L3, [RH, Score=133, Expect=9e-31]} {Mouse: ENSMUSG00000028184, Adgrl2, adhesion G protein-coupled receptor L2, [RH, Score=142, Expect=1e-33]; ENSMUSG00000013033, Adgrl1, adhesion G protein-coupled receptor L1, [RH, Score=140, Expect=6e-33]} {Celegans: WBGene00002252, lat-2, Latrophilin-like protein LAT-2, [RH, Score=124, Expect=2e-28]} {Smed: dd_Smed_v6_16446_0_2, dd_Smed_v6_16446_0_2, [RH, Score=444, Expect=1e-139]} {RNA1509_25495} {RNA1310_3070} {RNA815_2153}
12. MligTC455_29119 68 1.42 Mlig455_050458

Neo: -

Age: -

Region-enriched R2: 5.525/0.01281

1.848 - - - 0.956 - 0.892 Mlig455_050458 {REF} {Length: 624} {RNA1509_53840} {RNA1310_67192} {RNA815_27042}
13. MligTC455_13423 1243 25.9 Mlig455_044368

Neo: -

Age: logFC(26M/2M)=-0.595

Region-enriched R7: 3.345/0.00033
Region-enriched R6: 2.355/0.04350

Regeneration-downregulated BL: -4.170

Regeneration-depleted BL: -4.170

1.842 - - - 0.884 - 0.958 Mlig455_044368 {REF} {Length: 544} {RNA1509_13677} {RNA1310_82629.1, RNA1509_13677} {RNA1509_13677, RNA815_40883}
14. MligTC455_37710 5814 121.13 Mlig455_023529, Mlig455_023635

Neo: -

Age: logFC(26M/2M)=0.275

Region-enriched R7: 2.382/0.00159

Regeneration-downregulated BL: -3.544

Regeneration-depleted BL: -3.544

1.839 - - - 0.967 - 0.872

Mlig455_023529 {REF} {Length: 1292} {RNA1509_13958} {RNA1310_54113} {RNA815_27382.1}

Mlig455_023635 {REF} {Length: 673} {RNA1509_13958, RNA1509_22495, RNA1509_30469, RNA1509_39550} {RNA1310_54113, RNA1509_13958, RNA1509_22495, RNA1509_30469, RNA1509_39550} {RNA1509_13958, RNA1509_22495, RNA1509_30469, RNA1509_39550, RNA815_27382.1}
15. MligTC455_46052 159 3.31 Mlig455_020714

Neo: -

Age: -

Region-enriched R2: 2.603/0.01508

TRAF5 1.815 - - - 0.858 - 0.957 Mlig455_020714 {REF} {Length: 919} {Human: ENSG00000082512, TRAF5, TNF receptor associated factor 5, [Score=90.5, Expect=3e-20]} {Mouse: ENSMUSG00000111385, Traf5, TNF receptor-associated factor 5, [Score=88.2, Expect=1e-20]; ENSMUSG00000026637, Traf5, TNF receptor-associated factor 5, [Score=88.2, Expect=1e-20]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=73.6, Expect=8e-15]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [Score=98.6, Expect=1e-23]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [Score=135, Expect=1e-36]} {RNA1310_36792.1} {RNA815_40908}
16. MligTC455_51184 3569 74.36 Mlig455_015275

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.511

Region-enriched R7: 2.009/0.00500

RRBP1 1.807 - - - 0.975 - 0.832 Mlig455_015275 {REF} {Length: 1199} {Human: ENSG00000125844, RRBP1, ribosome binding protein 1, [Score=76.6, Expect=2e-15]} {Mouse: ENSMUSG00000027422, Rrbp1, ribosome binding protein 1, [Score=83.2, Expect=7e-18]} {Celegans: WBGene00001446, flp-3, FMRFamide-like neuropeptides 3 SPLGTMRF-amide TPLGTMRF-amide SAEPFGTMRF-amide NPENDTPFGTMRF-amide ASEDALFGTMRF-amide EAEEPLGTMRF-amide SADDSAPFGTMRF-amide NPLGTMRF-amide, [Score=44.7, Expect=1e-05]} {RNA1509_7521} {RNA1310_33007.1} {RNA815_34283}
17. MligTC455_51183 3580 74.57 Mlig455_015151

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.516

Region-enriched R7: 1.993/0.00499

RRBP1 1.806 - - - 0.975 - 0.831 Mlig455_015151 {REF} {Length: 1212} {Human: ENSG00000125844, RRBP1, ribosome binding protein 1, [Score=79.0, Expect=5e-16]} {Mouse: ENSMUSG00000027422, Rrbp1, ribosome binding protein 1, [Score=84.0, Expect=4e-18]} {Celegans: WBGene00001446, flp-3, FMRFamide-like neuropeptides 3 SPLGTMRF-amide TPLGTMRF-amide SAEPFGTMRF-amide NPENDTPFGTMRF-amide ASEDALFGTMRF-amide EAEEPLGTMRF-amide SADDSAPFGTMRF-amide NPLGTMRF-amide, [Score=45.1, Expect=9e-06]} {RNA1509_7521} {RNA1310_33007.1} {RNA815_34284}
18. MligTC455_25113 762 15.87 Mlig455_020768

Neo: -

Age: Down-Up-Down

Region-enriched R7: 2.653/0.00004
Region-enriched R2: 2.201/0.02449

1.799 - - - 0.966 - 0.833 Mlig455_020768 {REF} {Length: 810} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [Score=46.2, Expect=1e-06]} {RNA1509_36958} {RNA1310_50245} {RNA815_48543}
19. MligTC455_12444 17 0.35 Mlig455_041806

Neo: -

Age: -

1.789 - - - 0.800 - 0.989 Mlig455_041806 {REF} {Length: 1758} {RNA1310_51055}
20. MligTC455_49285 164 3.41 Mlig455_004486, Mlig455_037380

Neo: -

Age: -

Region-specific R2: 6.095

Region-enriched R2: 5.942/0.00244

LEF1 1.789 - - - 0.956 - 0.833

Mlig455_004486 {REF} {Length: 3612} {Pfam: HMG (high mobility group) box [PF00505.21, score=30.1]} {Human: ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [Score=105, Expect=2e-24]; ENSG00000081059, TCF7, transcription factor 7, [Score=103, Expect=3e-25]; ENSG00000152284, TCF7L1, transcription factor 7 like 1, [Score=100, Expect=2e-22]} {Mouse: ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [Score=105, Expect=6e-25]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [Score=101, Expect=8e-24]; ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [Score=100, Expect=1e-22]} {Dmel: FBgn0085432, pan, pangolin, [Score=103, Expect=1e-23]} {Celegans: WBGene00004077, pop-1, [Score=82.0, Expect=8e-17]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [Score=114, Expect=3e-29]} {RNA1509_13914} {RNA1310_16097} {RNA815_47141}

Mlig455_037380 {REF} {Length: 3365} {Pfam: HMG (high mobility group) box [PF00505.21, score=78.7]; HMG-box domain [PF09011.12, score=32.5]} {Human: ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=156, Expect=1e-43]; ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=154, Expect=7e-41]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=154, Expect=3e-44]; ENSG00000148737, TCF7L2, transcription factor 7 like 2, [RH, Score=150, Expect=6e-44]} {Mouse: ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=157, Expect=9e-44]; ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=156, Expect=1e-41]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=153, Expect=1e-42]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=155, Expect=1e-40]} {Celegans: WBGene00004077, pop-1, [Score=104, Expect=4e-24]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=165, Expect=2e-48]} {RNA1509_13914} {RNA1310_16097} {RNA815_47141}
21. MligTC455_12770 38 0.79 Mlig455_029135

Neo: -

Age: -

1.778 - - - 0.958 - 0.820 Mlig455_029135 {REF} {Length: 641} {RNA1509_20946} {RNA1310_48952} {RNA815_4785.1}
22. MligTC455_52128 26 0.54 Mlig455_056382

Neo: -

Age: -

1.769 - - - 0.952 - 0.817 Mlig455_056382 {REF} {Length: 892} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=20.5]; Ankyrin repeat [PF00023.32, score=19.7]} {RNA1310_149618}
23. MligTC455_10719 61 1.26 Mlig455_041088

Neo: -

Age: -

1.763 - - - 0.808 - 0.955 Mlig455_041088 {REF} {Length: 338} {NoTransDecoderORF} {RNA1310_18998}
24. MligTC455_11785 333 6.93 Mlig455_055379

Neo: Germline

Age: -

NUCB2 1.755 0.791 - 0.964 - - - Mlig455_055379 {REF} {Length: 2224} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=30.1]; EF-hand domain pair [PF13499.8, score=29.7]; EF-hand domain [PF13405.8, score=29.6]} {Human: ENSG00000070081, NUCB2, nucleobindin 2, [RH, Score=211, Expect=7e-64]; ENSG00000104805, NUCB1, nucleobindin 1, [RH, Score=211, Expect=1e-63]} {Mouse: ENSMUSG00000030824, Nucb1, nucleobindin 1, [RH, Score=219, Expect=9e-67]; ENSMUSG00000030659, Nucb2, nucleobindin 2, [RH, Score=209, Expect=3e-63]} {Dmel: FBgn0052190, NUCB1, [RH, Score=198, Expect=6e-58]} {Celegans: WBGene00009674, nucb-1, NUCleoBindin homolog, [RH, Score=172, Expect=3e-49]} {Smed: dd_Smed_v6_1728_0_1, dd_Smed_v6_1728_0_1, [RH, Score=263, Expect=1e-84]} {RNA1509_7514} {RNA1310_17099, RNA1509_7514} {RNA1509_7514, RNA815_6975}
25. MligTC455_49863 62 1.29 Mlig455_019320, Mlig455_019542

Neo: -

Age: -

SHOX2 1.754 - - - 0.792 - 0.962

Mlig455_019320 {REF} {Length: 1251} {Pfam: Homeodomain [PF00046.31, score=83.4]; Homeobox KN domain [PF05920.13, score=23.0]} {Human: ENSG00000168779, SHOX2, short stature homeobox 2, [Score=88.2, Expect=5e-21]; ENSG00000185960, SHOX, short stature homeobox, [Score=86.3, Expect=7e-20]} {Mouse: ENSMUSG00000027833, Shox2, short stature homeobox 2, [Score=88.2, Expect=3e-21]} {Dmel: FBgn0085396, CG34367, [Score=89.4, Expect=7e-21]} {Celegans: WBGene00006744, unc-4, Homeobox protein unc-4, [Score=84.0, Expect=2e-19]} {Smed: dd_Smed_v6_22163_0_1, dd_Smed_v6_22163_0_1, [Score=87.0, Expect=8e-20]} {RNA1310_51707} {RNA815_41055}

Mlig455_019542 {REF} {Length: 1249} {Pfam: Homeodomain [PF00046.31, score=83.4]; Homeobox KN domain [PF05920.13, score=23.0]} {Human: ENSG00000168779, SHOX2, short stature homeobox 2, [Score=88.6, Expect=4e-21]; ENSG00000185960, SHOX, short stature homeobox, [Score=86.3, Expect=6e-20]} {Mouse: ENSMUSG00000027833, Shox2, short stature homeobox 2, [Score=88.6, Expect=3e-21]} {Dmel: FBgn0085396, CG34367, [Score=89.4, Expect=7e-21]} {Celegans: WBGene00006744, unc-4, Homeobox protein unc-4, [Score=86.7, Expect=3e-20]} {Smed: dd_Smed_v6_22163_0_1, dd_Smed_v6_22163_0_1, [Score=87.0, Expect=8e-20]} {RNA1310_51707} {RNA815_41055}
26. MligTC455_38657 292 6.08 Mlig455_021581

Neo: -

Age: -

CPLX1 1.748 - - - 0.787 - 0.961 Mlig455_021581 {REF} {Length: 2085} {Pfam: Synaphin protein [PF05835.14, score=132.9]} {Human: ENSG00000168993, CPLX1, complexin 1, [Score=52.4, Expect=8e-09]; ENSG00000145920, CPLX2, complexin 2, [Score=50.8, Expect=1e-08]} {Mouse: ENSMUSG00000033615, Cplx1, complexin 1, [Score=53.5, Expect=2e-09]} {Dmel: FBgn0041605, cpx, complexin, [RH, Score=90.1, Expect=1e-23]} {Celegans: WBGene00022271, cpx-1, Putative complexin-1, [RH, Score=99.4, Expect=2e-27]} {Smed: dd_Smed_v6_9918_0_1, dd_Smed_v6_9918_0_1, [Score=94.4, Expect=2e-25]} {RNA1509_37151, RNA1509_38047} {RNA1310_51275, RNA1509_38047} {RNA1509_38047, RNA815_22799}
27. MligTC455_42510 125 2.6 Mlig455_025998, Mlig455_070424

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.702

1.748 - - - 0.955 - 0.793

Mlig455_025998 {REF} {Length: 1369} {RNA1310_73875.1}

Mlig455_070424 {REF} {Length: 1082} {RNA1310_73875.1}
28. MligTC455_25858 48 1 Mlig455_005649, Mlig455_005698, Mlig455_008659

Neo: -

Age: -

1.736 - - - 0.971 - 0.765

Mlig455_005649 {REF} {Length: 1060} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=27.0]} {RNA1509_35414} {RNA1310_2501.1} {RNA815_9496.1}

Mlig455_005698 {REF} {Length: 1505} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=26.8]} {RNA1509_35414} {RNA1310_2501.1} {RNA815_9496.1}

Mlig455_008659 {REF} {Length: 1151} {TRANSSPLICED} {Pfam: haloacid dehalogenase-like hydrolase [PF08282.14, score=19.9]} {RNA1509_25258} {RNA1310_56236} {RNA815_9496.1}
29. MligTC455_10966 15 0.31 Mlig455_013154

Neo: -

Age: -

1.735 - - - 0.952 - 0.783 Mlig455_013154 {REF} {Length: 827} {Pfam: Lectin C-type domain [PF00059.23, score=21.8]} {RNA1509_20946} {RNA1310_65161} {RNA815_4785.1}
30. MligTC455_12084 16 0.34 Mlig455_033067

Neo: -

Age: -

1.733 - - - 0.974 - 0.759 Mlig455_033067 {REF} {Length: 1019} {RNA1310_38733.1} {RNA815_44268}
31. MligTC455_15859 120 2.49 Mlig455_007414, Mlig455_067681

Neo: -

Age: -

1.723 - - - 0.960 - 0.763

Mlig455_007414 {REF} {Length: 914} {RNA1310_61579} {RNA815_24378}

Mlig455_067681 {REF} {Length: 917} {RNA1310_61579} {RNA815_24378}
32. MligTC455_12269 42 0.88 Mlig455_062448

Neo: -

Age: -

Region-enriched R2: 6.351/0.02912

1.718 - - - 0.954 - 0.764 Mlig455_062448 {REF} {Length: 941} {RNA1310_43338} {RNA815_24238}
33. MligTC455_49957 119 2.47 Mlig455_005610, Mlig455_014448

Neo: -

Age: -

1.718 - - - 0.959 - 0.759

Mlig455_005610 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=66.2, Expect=4e-13]} {RNA1310_45206} {RNA815_28788}

Mlig455_014448 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=63.2, Expect=6e-12]} {RNA1310_45206} {RNA815_28788}
34. MligTC455_10567 11 0.23 Mlig455_012840

Neo: -

Age: -

TNN 1.715 - - - 0.956 - 0.759 Mlig455_012840 {REF} {Length: 1231} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=140.5]; PAN domain [PF00024.28, score=19.1]} {Human: ENSG00000120332, TNN, tenascin N, [Score=104, Expect=2e-24]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=103, Expect=3e-25]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=103, Expect=3e-24]; ENSG00000116147, TNR, tenascin R, [Score=101, Expect=2e-23]; ENSG00000171564, FGB, fibrinogen beta chain, [Score=100, Expect=3e-23]; ENSG00000160339, FCN2, ficolin 2, [Score=99.0, Expect=1e-23]} {Mouse: ENSMUSG00000026938, Fcna, ficolin A, [Score=107, Expect=7e-27]; ENSMUSG00000026725, Tnn, tenascin N, [Score=102, Expect=5e-24]; ENSMUSG00000015829, Tnr, tenascin R, [Score=102, Expect=7e-24]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=102, Expect=3e-24]} {Dmel: FBgn0050280, CG30280, [Score=110, Expect=1e-28]} {Celegans: WBGene00012782, Y43C5A.2, [RH, Score=53.1, Expect=8e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=98.2, Expect=5e-23]}
35. MligTC455_14469 10 0.21 Mlig455_023311

Neo: -

Age: -

1.713 - - - 0.954 - 0.759 Mlig455_023311 {REF} {Length: 863} {NoTransDecoderORF} {RNA1310_48186} {RNA815_36304}
36. MligTC455_32028 19 0.39 Mlig455_019343, Mlig455_019346

Neo: -

Age: -

GRIA2 1.713 - - - 0.976 - 0.737

Mlig455_019343 {REF} {Length: 3241} {Pfam: Ligand-gated ion channel [PF00060.28, score=96.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=57.9]; Receptor family ligand binding region [PF01094.30, score=49.1]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.0]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=150, Expect=1e-36]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=149, Expect=2e-36]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=146, Expect=2e-35]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=144, Expect=9e-35]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=144, Expect=1e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=150, Expect=5e-37]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=150, Expect=8e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=145, Expect=3e-35]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=3e-35]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=144, Expect=5e-35]} {Dmel: FBgn0039927, CG11155, [Score=158, Expect=1e-39]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=125, Expect=3e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=250, Expect=2e-75]} {RNA1509_10728} {RNA1310_4026} {RNA815_8415.1}

Mlig455_019346 {REF} {Length: 519} {Pfam: Receptor family ligand binding region [PF01094.30, score=21.5]} {RNA1509_10728} {RNA1310_4026} {RNA815_8415.2}
37. MligTC455_13904 16 0.34 Mlig455_006146, Mlig455_006158

Neo: -

Age: -

1.712 - - - 0.953 - 0.759

Mlig455_006146 {REF} {Length: 1064} {Pfam: F5/8 type C domain [PF00754.27, score=25.2]; PAN domain [PF00024.28, score=18.8]} {Smed: dd_Smed_v6_70328_0_1, dd_Smed_v6_70328_0_1, [RH, Score=52.4, Expect=3e-09]} {RNA1310_107210}

Mlig455_006158 {REF} {Length: 1021} {Pfam: F5/8 type C domain [PF00754.27, score=25.0]} {Smed: dd_Smed_v6_70328_0_1, dd_Smed_v6_70328_0_1, [RH, Score=52.4, Expect=5e-09]} {RNA1310_107210}
38. MligTC455_50355 38 0.79 Mlig455_057631

Neo: -

Age: -

Region-enriched R2: 7.639/0.01837

1.709 - - - 0.957 - 0.752 Mlig455_057631 {REF} {Length: 1003} {Pfam: WSC domain [PF01822.21, score=45.2]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=6e-06]} {RNA1310_44307} {RNA815_33128}
39. MligTC455_45487 110 2.3 Mlig455_004129, Mlig455_060457

Neo: -

Age: -

1.707 - - - 0.953 - 0.754

Mlig455_004129 {REF} {Length: 1131} {Pfam: PAN domain [PF00024.28, score=18.8]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1310_37660} {RNA815_17816.1}

Mlig455_060457 {REF} {Length: 1507} {Pfam: PAN domain [PF00024.28, score=19.5]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_54623} {RNA1310_33480} {RNA815_17816.1}
40. MligTC455_16610 98 2.05 Mlig455_069894

Neo: -

Age: -

Region-enriched R2: 5.254/0.03136

WSCD2 1.705 - - - 0.951 - 0.754 Mlig455_069894 {REF} {Length: 827} {Pfam: WSC domain [PF01822.21, score=59.2]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=55.1, Expect=4e-09]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=47.8, Expect=9e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=52.4, Expect=2e-08]} {RNA1509_46267} {RNA1310_46146} {RNA815_32275.1}
41. MligTC455_19708 304 6.32 Mlig455_009784

Neo: -

Age: -

Region-enriched R2: 6.355/0.00039

1.704 - - - 0.954 - 0.750 Mlig455_009784 {REF} {Length: 826} {Pfam: Pancreatic hormone peptide [PF00159.20, score=43.3]} {RNA1509_54211} {RNA1310_54505.1, RNA1509_54211} {RNA1509_54211, RNA815_29389}
42. MligTC455_12512 80 1.68 Mlig455_017689

Neo: -

Age: -

1.7 - - - 0.952 - 0.748 Mlig455_017689 {REF} {Length: 934} {RNA1310_37507} {RNA815_32171}
43. MligTC455_18140 171 3.56 Mlig455_033232

Neo: -

Age: Up-Down-Down

Region-specific R2: 6.925

Region-enriched R2: 6.274/0.02921

TRPC5 1.7 - - - 0.966 - 0.734 Mlig455_033232 {REF} {Length: 4524} {Pfam: Ion transport protein [PF00520.33, score=98.6]; Transient receptor ion channel II [PF08344.13, score=94.3]; Polycystin cation channel [PF08016.14, score=49.0]; Ankyrin repeats (many copies) [PF13637.8, score=37.2]; Ankyrin repeats (3 copies) [PF12796.9, score=33.2]; Ankyrin repeat [PF13606.8, score=25.5]; Ankyrin repeats (many copies) [PF13857.8, score=24.1]; Ankyrin repeat [PF00023.32, score=23.2]} {Human: ENSG00000072315, TRPC5, transient receptor potential cation channel subfamily C member 5, [RH, Score=743, Expect=0.0]; ENSG00000133107, TRPC4, transient receptor potential cation channel subfamily C member 4, [RH, Score=742, Expect=0.0]} {Mouse: ENSMUSG00000041710, Trpc5, transient receptor potential cation channel, subfamily C, member 5, [RH, Score=745, Expect=0.0]; ENSMUSG00000027748, Trpc4, transient receptor potential cation channel, subfamily C, member 4, [RH, Score=742, Expect=0.0]} {Dmel: FBgn0032593, Trpgamma, Transient receptor potential cation channel gamma, [RH, Score=848, Expect=0.0]} {Celegans: WBGene00006615, trp-2, TRP (Transient receptor potential) channel family; TRP homlogous cation channel protein, [RH, Score=696, Expect=0.0]} {Smed: dd_Smed_v6_20495_0_1, dd_Smed_v6_20495_0_1, [RH, Score=1016, Expect=0.0]} {RNA1509_34138} {RNA1310_12839} {RNA815_17637}
44. MligTC455_40616 20 0.41 Mlig455_043384, Mlig455_043410

Neo: -

Age: -

WSCD2 1.699 - - - 0.959 - 0.740

Mlig455_043384 {REF} {Length: 805} {Pfam: WSC domain [PF01822.21, score=54.4]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=57.4, Expect=3e-09]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=57.8, Expect=2e-09]}

Mlig455_043410 {REF} {Length: 804}
45. MligTC455_18099 24 0.51 Mlig455_036525

Neo: -

Age: -

PPA1 1.695 - - - 0.951 - 0.744 Mlig455_036525 {REF} {Length: 1911} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1310_57333.1} {RNA815_22340}
46. MligTC455_10160 19 0.39 Mlig455_006145, Mlig455_006156

Neo: -

Age: -

1.689 - - - 0.954 - 0.735

Mlig455_006145 {REF} {Length: 984} {Pfam: F5/8 type C domain [PF00754.27, score=28.4]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [Score=64.3, Expect=4e-13]} {RNA1310_84805}

Mlig455_006156 {REF} {Length: 982} {Pfam: F5/8 type C domain [PF00754.27, score=27.7]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [Score=62.8, Expect=1e-12]} {RNA1310_84805}
47. MligTC455_30007 11 0.23 Mlig455_037416

Neo: -

Age: -

CHRNB3 1.675 - - - 0.954 - 0.721 Mlig455_037416 {REF} {Length: 1764} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=119.4]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=71.0]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=139, Expect=9e-36]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=133, Expect=1e-33]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=142, Expect=5e-37]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=140, Expect=3e-36]} {Dmel: FBgn0004118, nAChRbeta2, nicotinic Acetylcholine Receptor beta2, [Score=149, Expect=2e-39]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=151, Expect=3e-40]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=149, Expect=9e-40]} {RNA1509_7752} {RNA1310_10606.2} {RNA815_23438}
48. MligTC455_10023 48 0.99 Mlig455_051817

Neo: -

Age: Down-Up-Down

1.674 - - - 0.703 - 0.971 Mlig455_051817 {REF} {Length: 3330} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=46.4]} {RNA1310_7348} {RNA815_14995}
49. MligTC455_11078 15 0.31 Mlig455_045628

Neo: -

Age: -

1.674 - - - 0.951 - 0.723 Mlig455_045628 {REF} {Length: 2373} {Pfam: Polycystin cation channel [PF08016.14, score=25.4]} {RNA1310_39436.1} {RNA815_35444}
50. MligTC455_44308 40 0.82 Mlig455_006155

Neo: -

Age: -

Region-enriched R2: 5.931/0.03949
Region-enriched R5: 4.482/0.01958

1.665 - - - 0.959 - 0.706 Mlig455_006155 {REF} {Length: 1184} {Pfam: F5/8 type C domain [PF00754.27, score=25.5]} {Smed: dd_Smed_v6_52492_0_1, dd_Smed_v6_52492_0_1, [Score=47.8, Expect=4e-07]} {RNA1509_2129} {RNA1310_49415} {RNA815_42540}
51. MligTC455_54276 40 0.83 Mlig455_017653, Mlig455_058981

Neo: -

Age: -

DIRAS2 0.982 - - - 0.982 - -

Mlig455_017653 {REF} {Length: 1214} {Pfam: Ras family [PF00071.24, score=143.5]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=61.6]; 50S ribosome-binding GTPase [PF01926.25, score=27.4]; ADP-ribosylation factor family [PF00025.23, score=24.5]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.1]} {Human: ENSG00000165023, DIRAS2, DIRAS family GTPase 2, [RH, Score=243, Expect=1e-81]} {Mouse: ENSMUSG00000047842, Diras2, DIRAS family, GTP-binding RAS-like 2, [RH, Score=243, Expect=3e-81]} {Dmel: FBgn0037754, CG8500, [RH, Score=226, Expect=1e-74]} {Celegans: WBGene00016911, drn-1, GTP-binding protein drn-1, [RH, Score=234, Expect=6e-78]} {Smed: dd_Smed_v6_10778_0_1, dd_Smed_v6_10778_0_1, [RH, Score=231, Expect=2e-77]} {RNA1310_105748}

Mlig455_058981 {REF} {Length: 3376} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=252.0]; Ras family [PF00071.24, score=140.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=59.1]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=43.1]; 50S ribosome-binding GTPase [PF01926.25, score=24.6]; Olfactory receptor [PF13853.8, score=24.0]} {Human: ENSG00000165023, DIRAS2, DIRAS family GTPase 2, [Score=243, Expect=3e-74]} {Mouse: ENSMUSG00000047842, Diras2, DIRAS family, GTP-binding RAS-like 2, [Score=241, Expect=6e-74]} {Dmel: FBgn0037754, CG8500, [RH, Score=224, Expect=2e-67]} {Celegans: WBGene00016911, drn-1, GTP-binding protein drn-1, [RH, Score=224, Expect=2e-67]} {Smed: dd_Smed_v6_20043_0_1, dd_Smed_v6_20043_0_1, [RH, Score=218, Expect=7e-62]} {RNA1509_25623} {RNA1310_22334} {RNA815_30775}
52. MligTC455_10775 50 1.05 Mlig455_023939

Neo: -

Age: -

GABBR1 0.979 - - 0.979 - - - Mlig455_023939 {REF} {Length: 3689} {TRANSSPLICED} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=159.6]; Receptor family ligand binding region [PF01094.30, score=113.8]; Periplasmic binding protein [PF13458.8, score=20.4]} {Human: ENSG00000237112, GABBR1, gamma-aminobutyric acid type B receptor subunit 1, [Score=166, Expect=5e-42]; ENSG00000206466, GABBR1, gamma-aminobutyric acid type B receptor subunit 1, [Score=166, Expect=5e-42]; ENSG00000232569, GABBR1, gamma-aminobutyric acid type B receptor subunit 1, [Score=166, Expect=5e-42]; ENSG00000237051, GABBR1, gamma-aminobutyric acid type B receptor subunit 1, [Score=166, Expect=5e-42]; ENSG00000206511, GABBR1, gamma-aminobutyric acid type B receptor subunit 1, [Score=166, Expect=5e-42]; ENSG00000204681, GABBR1, gamma-aminobutyric acid type B receptor subunit 1, [Score=166, Expect=5e-42]; ENSG00000232632, GABBR1, gamma-aminobutyric acid type B receptor subunit 1, [Score=166, Expect=5e-42]} {Mouse: ENSMUSG00000024462, Gabbr1, gamma-aminobutyric acid (GABA) B receptor, 1, [Score=166, Expect=6e-42]} {Dmel: FBgn0031275, GABA-B-R3, metabotropic GABA-B receptor subtype 3, [Score=151, Expect=3e-37]} {Celegans: WBGene00022675, gbb-2, GABA B receptor subunit; GABAB2 receptor subunit, [Score=123, Expect=8e-29]} {Smed: dd_Smed_v6_51663_0_1, dd_Smed_v6_51663_0_1, [Score=72.4, Expect=6e-14]} {RNA1509_12849} {RNA1310_9423.1} {RNA815_7350.2}
53. MligTC455_15540 90 1.87 Mlig455_004018

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.706

SYT7 0.978 - - - 0.978 - - Mlig455_004018 {REF} {Length: 2288} {Pfam: C2 domain [PF00168.32, score=65.8]} {Human: ENSG00000011347, SYT7, synaptotagmin 7, [Score=109, Expect=3e-26]; ENSG00000143858, SYT2, synaptotagmin 2, [Score=107, Expect=2e-25]; ENSG00000067715, SYT1, synaptotagmin 1, [Score=105, Expect=1e-24]} {Mouse: ENSMUSG00000026452, Syt2, synaptotagmin II, [Score=107, Expect=1e-25]; ENSMUSG00000035864, Syt1, synaptotagmin I, [Score=105, Expect=1e-24]; ENSMUSG00000027849, Syt6, synaptotagmin VI, [Score=104, Expect=1e-24]} {Dmel: FBgn0004242, Syt1, Synaptotagmin 1, [Score=110, Expect=1e-26]} {Celegans: WBGene00004926, snt-6, SyNapTotagmin, [Score=117, Expect=1e-29]} {Smed: dd_Smed_v6_4222_0_1, dd_Smed_v6_4222_0_1, [Score=104, Expect=4e-25]} {RNA1509_38256} {RNA1310_13836} {RNA815_4752.1}
54. MligTC455_02209 16 0.33 Mlig455_008646

Neo: -

Age: -

0.974 - - - - - 0.974 Mlig455_008646 {REF} {Length: 969} {RNA1310_71752} {RNA815_58220}
55. MligTC455_29991 55 1.14 Mlig455_035129, Mlig455_040144

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.706

0.974 - - - - - 0.974

Mlig455_035129 {REF} {Length: 406} {Pfam: Mab-21 protein [PF03281.16, score=26.3]} {RNA1509_26004} {RNA1310_36482} {RNA815_1664.2}

Mlig455_040144 {REF} {Length: 2361} {Pfam: Mab-21 protein [PF03281.16, score=40.1]} {RNA1509_26004} {RNA1310_3906.1} {RNA815_1664.1}
56. MligTC455_34949 30 0.63 Mlig455_055437

Neo: -

Age: -

RIMS1 0.974 - - - - - 0.974 Mlig455_055437 {REF} {Length: 5246} {Pfam: C2 domain [PF00168.32, score=104.4]; PDZ domain [PF17820.3, score=39.9]; PDZ domain [PF00595.26, score=32.1]; Piccolo Zn-finger [PF05715.15, score=24.7]; PDZ domain [PF13180.8, score=24.0]; FYVE-type zinc finger [PF02318.18, score=19.4]} {Human: ENSG00000079841, RIMS1, regulating synaptic membrane exocytosis 1, [RH, Score=239, Expect=2e-63]; ENSG00000176406, RIMS2, regulating synaptic membrane exocytosis 2, [RH, Score=238, Expect=2e-63]} {Mouse: ENSMUSG00000037386, Rims2, regulating synaptic membrane exocytosis 2, [RH, Score=241, Expect=3e-64]; ENSMUSG00000111628, Rims1, regulating synaptic membrane exocytosis 1, [RH, Score=240, Expect=1e-66]; ENSMUSG00000041670, Rims1, regulating synaptic membrane exocytosis 1, [RH, Score=240, Expect=1e-66]} {Dmel: FBgn0053547, Rim, Rab3 interacting molecule, [RH, Score=243, Expect=6e-65]} {Celegans: WBGene00006750, unc-10, Rab-3-interacting molecule unc-10, [RH, Score=187, Expect=1e-47]} {Smed: dd_Smed_v6_10734_0_1, dd_Smed_v6_10734_0_1, [RH, Score=281, Expect=6e-80]} {RNA1509_26372} {RNA1310_18417, RNA1509_26372} {RNA1509_26372, RNA815_9566}
57. MligTC455_13933 17 0.36 Mlig455_020749

Neo: -

Age: -

0.972 0.972 - - - - - Mlig455_020749 {REF} {Length: 469} {NoTransDecoderORF} {RNA1310_111476}
58. MligTC455_43566 36 0.76 Mlig455_056590

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.289

0.972 - - 0.972 - - - Mlig455_056590 {REF} {Length: 10047} {TRANSSPLICED} {Smed: dd_Smed_v6_5859_0_1, dd_Smed_v6_5859_0_1, [Score=93.2, Expect=3e-20]} {RNA1509_7758} {RNA1310_5822, RNA1509_7758} {RNA1509_7758, RNA815_2990}
59. MligTC455_14777 27 0.57 Mlig455_047922

Neo: -

Age: logFC(26M/2M)=3.264

0.971 - - - 0.971 - - Mlig455_047922 {REF} {Length: 1082} {RNA1509_18414} {RNA1310_121111} {RNA815_19425}
60. MligTC455_38292 148 3.09 Mlig455_057300

Neo: -

Age: -

TUBD1 0.971 - - - 0.971 - - Mlig455_057300 {REF} {Length: 3000} {TRANSSPLICED} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=149.3]; Tubulin like [PF13809.8, score=18.2]} {Human: ENSG00000108423, TUBD1, tubulin delta 1, [RH, Score=354, Expect=6e-118]} {Mouse: ENSMUSG00000020513, Tubd1, tubulin, delta 1, [RH, Score=354, Expect=5e-118]} {Dmel: FBgn0010097, gammaTub37C, gamma-Tubulin at 37C, [Score=134, Expect=3e-34]} {Celegans: WBGene00003171, mec-7, Tubulin beta-1 chain, [Score=134, Expect=2e-34]} {Smed: dd_Smed_v6_15819_0_4, dd_Smed_v6_15819_0_4, [RH, Score=321, Expect=1e-105]} {RNA1509_37116} {RNA1310_16834.1, RNA1509_37116} {RNA1509_37116, RNA815_17890}
61. MligTC455_07515 13 0.27 Mlig455_048357

Neo: -

Age: -

HCRTR1 0.97 - - - - - 0.970 Mlig455_048357 {REF} {Length: 1740} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=51.8]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=38.9]} {Human: ENSG00000121764, HCRTR1, hypocretin receptor 1, [Score=49.7, Expect=6e-06]} {Mouse: ENSMUSG00000028778, Hcrtr1, hypocretin (orexin) receptor 1, [Score=49.7, Expect=4e-06]} {Dmel: FBgn0029723, Proc-R, Proctolin receptor, [Score=52.0, Expect=5e-07]} {Smed: dd_Smed_v6_27761_0_1, dd_Smed_v6_27761_0_1, [Score=103, Expect=3e-24]} {RNA1509_33416} {RNA1310_68701}
62. MligTC455_12493 13 0.27 Mlig455_008188

Neo: -

Age: -

Region-enriched R4: 6.390/0.01110

0.969 - - - 0.969 - - Mlig455_008188 {REF} {Length: 1719} {Pfam: F5/8 type C domain [PF00754.27, score=27.7]} {Smed: dd_Smed_v6_52492_0_1, dd_Smed_v6_52492_0_1, [Score=47.4, Expect=6e-07]} {RNA1310_131684}
63. MligTC455_27468 40 0.84 Mlig455_013749

Neo: -

Age: -

LNPEP 0.968 - - - - - 0.968 Mlig455_013749 {REF} {Length: 4937} {Pfam: Peptidase family M1 domain [PF01433.22, score=195.1]; Peptidase M1 N-terminal domain [PF17900.3, score=121.7]} {Human: ENSG00000113441, LNPEP, leucyl and cystinyl aminopeptidase, [Score=289, Expect=5e-85]; ENSG00000172901, LVRN, laeverin, [Score=282, Expect=1e-82]; ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=277, Expect=4e-81]; ENSG00000164307, ERAP1, endoplasmic reticulum aminopeptidase 1, [Score=275, Expect=3e-80]} {Mouse: ENSMUSG00000023845, Lnpep, leucyl/cystinyl aminopeptidase, [Score=286, Expect=2e-84]} {Dmel: FBgn0052473, CG32473, [Score=293, Expect=9e-88]} {Celegans: WBGene00003914, pam-1, Aminopeptidase, [Score=251, Expect=2e-72]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=328, Expect=5e-100]} {RNA1509_14706} {RNA1310_6661.1} {RNA815_1900.2}
64. MligTC455_10403 12 0.24 Mlig455_031881

Neo: -

Age: -

HTR1A 0.965 - - - - - 0.965 Mlig455_031881 {REF} {Length: 1725} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=229.5]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=39.9]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=28.4]} {Human: ENSG00000178394, HTR1A, 5-hydroxytryptamine receptor 1A, [Score=186, Expect=3e-53]; ENSG00000150594, ADRA2A, adrenoceptor alpha 2A, [Score=184, Expect=8e-52]} {Mouse: ENSMUSG00000021721, Htr1a, 5-hydroxytryptamine (serotonin) receptor 1A, [Score=191, Expect=5e-55]; ENSMUSG00000033717, Adra2a, adrenergic receptor, alpha 2a, [Score=189, Expect=6e-54]} {Dmel: FBgn0004573, 5-HT7, 5-hydroxytryptamine (serotonin) receptor 7, [Score=167, Expect=2e-45]} {Celegans: WBGene00017157, tyra-2, Tyramine receptor tyra-2, [Score=186, Expect=3e-53]} {Smed: dd_Smed_v6_33950_0_1, dd_Smed_v6_33950_0_1, [Score=244, Expect=3e-75]} {RNA1310_74800}
65. MligTC455_28593 775 16.14 Mlig455_003148, Mlig455_003154, Mlig455_006839, Mlig455_008205, Mlig455_032426, Mlig455_034912, Mlig455_039851, Mlig455_051606, Mlig455_070582

Neo: -

Age: Up-Down-Down

0.964 - - 0.964 - - -

Mlig455_003148 {REF} {Length: 1515} {NoTransDecoderORF} {RNA1509_20409} {RNA1310_17062} {RNA815_22796.1}

Mlig455_003154 {REF} {Length: 1543} {NoTransDecoderORF} {RNA1509_20409} {RNA1310_17062} {RNA815_22796.1}

Mlig455_006839 {REF} {Length: 1674} {NoTransDecoderORF} {RNA1509_20409} {RNA1310_17062} {RNA815_22796.1}

Mlig455_008205 {REF} {Length: 2497} {NoTransDecoderORF} {RNA1509_57922} {RNA1310_17062} {RNA815_22796.1}

Mlig455_032426 {REF} {Length: 768} {NoTransDecoderORF} {RNA1509_57922} {RNA1310_17737.3} {RNA815_22796.1}

Mlig455_034912 {REF} {Length: 2965} {NoTransDecoderORF} {RNA1509_20409, RNA1509_43211} {RNA1310_17062, RNA1509_43211} {RNA1509_43211, RNA815_22796.1}

Mlig455_039851 {REF} {Length: 4859} {NoTransDecoderORF} {RNA1509_57922} {RNA1310_17062} {RNA815_22796.1}

Mlig455_051606 {REF} {Length: 1496} {NoTransDecoderORF} {RNA1509_20409} {RNA1310_17062} {RNA815_22796.1}

Mlig455_070582 {REF} {Length: 1319} {NoTransDecoderORF} {RNA1509_20409} {RNA1310_17062} {RNA815_22796.1}
66. MligTC455_38012 17 0.35 Mlig455_037323, Mlig455_040296

Neo: -

Age: -

0.961 - - 0.961 - - -

Mlig455_037323 {REF} {Length: 405} {NoTransDecoderORF} {RNA1310_81014.1}

Mlig455_040296 {REF} {Length: 180} {NoTransDecoderORF} {RNA1310_81014.2}
67. MligTC455_12170 12 0.25 Mlig455_009789, Mlig455_009791

Neo: -

Age: -

0.96 - - - - - 0.960

Mlig455_009789 {REF} {Length: 189} {NoTransDecoderORF}

Mlig455_009791 {REF} {Length: 1636} {RNA1310_75425}
68. MligTC455_12231 98 2.04 Mlig455_036385

Neo: -

Age: -

0.96 - - - 0.960 - - Mlig455_036385 {REF} {Length: 831} {NoTransDecoderORF} {RNA1509_32623} {RNA1310_46301} {RNA815_22921}
69. MligTC455_16735 31 0.64 Mlig455_010958, Mlig455_033088

Neo: -

Age: -

0.959 - - - - - 0.959

Mlig455_010958 {REF} {Length: 959} {RNA1509_35668} {RNA1310_30833} {RNA815_18824.1}

Mlig455_033088 {REF} {Length: 912} {RNA1509_35668} {RNA1310_30833} {RNA815_18824.1}
70. MligTC455_15727 112 2.33 Mlig455_027846, Mlig455_060005

Neo: -

Age: -

0.958 - - - 0.958 - -

Mlig455_027846 {REF} {Length: 910} {Smed: dd_Smed_v6_31751_0_1, dd_Smed_v6_31751_0_1, [RH, Score=47.4, Expect=5e-07]} {RNA1509_36923} {RNA1310_38586} {RNA815_19219}

Mlig455_060005 {REF} {Length: 991} {RNA1509_36923} {RNA1310_38586} {RNA815_19219}
71. MligTC455_36599 36 0.75 Mlig455_030316, Mlig455_034137

Neo: -

Age: -

0.958 - - - - - 0.958

Mlig455_030316 {REF} {Length: 755} {NoTransDecoderORF} {RNA1509_51255} {RNA1310_60503} {RNA815_39433}

Mlig455_034137 {REF} {Length: 518} {NoTransDecoderORF} {RNA1509_51255} {RNA1310_60503} {RNA815_39433}
72. MligTC455_40389 5 0.1 Mlig455_059080

Neo: -

Age: Down-Up-Down

0.958 - - - 0.958 - - Mlig455_059080 {REF} {Length: 2631} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=44.9]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [Score=141, Expect=6e-37]} {RNA1310_29891} {RNA815_15562}
73. MligTC455_44188 22 0.46 Mlig455_061616

Neo: -

Age: -

0.958 - - - 0.958 - - Mlig455_061616 {REF} {Length: 947} {Smed: dd_Smed_v6_14508_0_1, dd_Smed_v6_14508_0_1, [Score=77.4, Expect=6e-17]} {RNA1310_100266} {RNA815_44274}
74. MligTC455_31685 83 1.73 Mlig455_036333, Mlig455_036334, Mlig455_036356, Mlig455_054550

Neo: -

Age: -

SLC5A7 0.957 - - - - - 0.957

Mlig455_036333 {REF} {Length: 491} {tRNA: Ala(CGC),pseudo, score=26.8} {RNA1509_45595} {RNA1310_13430.1} {RNA815_31014}

Mlig455_036334 {REF} {Length: 599} {NoTransDecoderORF} {RNA1310_51434} {RNA815_35996}

Mlig455_036356 {REF} {Length: 4094} {tRNA: Ala(CGC),pseudo, score=26.8} {Pfam: Sodium:solute symporter family [PF00474.19, score=114.3]} {Human: ENSG00000115665, SLC5A7, solute carrier family 5 member 7, [RH, Score=591, Expect=0.0]} {Mouse: ENSMUSG00000023945, Slc5a7, solute carrier family 5 (choline transporter), member 7, [RH, Score=595, Expect=0.0]} {Dmel: FBgn0038641, CG7708, [RH, Score=602, Expect=0.0]} {Celegans: WBGene00000501, cho-1, High-affinity choline transporter 1, [RH, Score=553, Expect=0.0]} {Smed: dd_Smed_v6_12883_0_1, dd_Smed_v6_12883_0_1, [RH, Score=649, Expect=0.0]} {RNA1509_56795} {RNA1310_15022.1} {RNA815_33275}

Mlig455_054550 {REF} {Length: 303} {NoTransDecoderORF} {RNA1509_46688} {RNA1310_146263} {RNA815_62938}
75. MligTC455_51194 408 8.5 Mlig455_007624, Mlig455_007645

Neo: -

Age: -

Region-specific R2: 3.993

Region-enriched R2: 3.717/0.00015

CDK5R1 0.957 - - - 0.957 - -

Mlig455_007624 {REF} {Length: 1990} {Pfam: Cyclin-dependent kinase 5 activator protein [PF03261.17, score=249.2]} {Human: ENSG00000176749, CDK5R1, cyclin dependent kinase 5 regulatory subunit 1, [RH, Score=191, Expect=7e-57]} {Mouse: ENSMUSG00000048895, Cdk5r1, cyclin-dependent kinase 5, regulatory subunit 1 (p35), [RH, Score=191, Expect=6e-57]} {Dmel: FBgn0027491, Cdk5alpha, Cdk5 activator-like protein, [RH, Score=199, Expect=2e-58]} {Celegans: WBGene00011955, cdka-1, Cyclin-dependent kinase 5 activator 1, [RH, Score=176, Expect=6e-51]} {Smed: dd_Smed_v6_13788_0_1, dd_Smed_v6_13788_0_1, [RH, Score=215, Expect=1e-66]} {RNA1509_28436} {RNA1310_14097} {RNA815_13436}

Mlig455_007645 {REF} {Length: 1937} {Pfam: Cyclin-dependent kinase 5 activator protein [PF03261.17, score=249.3]} {Human: ENSG00000176749, CDK5R1, cyclin dependent kinase 5 regulatory subunit 1, [RH, Score=191, Expect=8e-57]} {Mouse: ENSMUSG00000048895, Cdk5r1, cyclin-dependent kinase 5, regulatory subunit 1 (p35), [RH, Score=191, Expect=5e-57]} {Dmel: FBgn0027491, Cdk5alpha, Cdk5 activator-like protein, [RH, Score=199, Expect=3e-58]} {Celegans: WBGene00011955, cdka-1, Cyclin-dependent kinase 5 activator 1, [RH, Score=177, Expect=2e-51]} {Smed: dd_Smed_v6_13788_0_1, dd_Smed_v6_13788_0_1, [RH, Score=216, Expect=1e-66]} {RNA1509_28436} {RNA1310_14097} {RNA815_13436}
76. MligTC455_18652 7 0.14 Mlig455_068511

Neo: -

Age: -

0.956 - - - 0.956 - - Mlig455_068511 {REF} {Length: 1872} {Smed: dd_Smed_v6_13648_0_1, dd_Smed_v6_13648_0_1, [Score=52.4, Expect=2e-07]} {RNA1310_85716}
77. MligTC455_27983 78 1.62 Mlig455_044762

Neo: -

Age: -

RASGRP1 0.956 - - - 0.956 - - Mlig455_044762 {REF} {Length: 3246} {TRANSSPLICED} {Pfam: RasGEF domain [PF00617.21, score=148.4]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=47.7]; EF-hand domain [PF13405.8, score=27.2]; EF-hand domain pair [PF13499.8, score=25.2]; EF hand [PF13202.8, score=24.3]; EF hand [PF00036.34, score=23.3]} {Human: ENSG00000172575, RASGRP1, RAS guanyl releasing protein 1, [RH, Score=451, Expect=3e-144]} {Mouse: ENSMUSG00000071042, Rasgrp3, RAS, guanyl releasing protein 3, [RH, Score=442, Expect=4e-143]; ENSMUSG00000027347, Rasgrp1, RAS guanyl releasing protein 1, [RH, Score=438, Expect=2e-140]} {Dmel: FBgn0001965, Sos, Son of sevenless, [Score=75.9, Expect=1e-13]} {Celegans: WBGene00009100, rgef-1, Rap Guanine nucleotide Exchange Factor homolog, [RH, Score=422, Expect=3e-136]} {Smed: dd_Smed_v6_15742_0_2, dd_Smed_v6_15742_0_2, [RH, Score=300, Expect=1e-93]} {RNA1509_53196} {RNA1310_11395} {RNA815_47062}
78. MligTC455_40626 37 0.76 Mlig455_066946

Neo: -

Age: -

Region-enriched R2: 4.441/0.03242

CD209 0.956 - - - 0.956 - - Mlig455_066946 {REF} {Length: 1316} {Pfam: Lectin C-type domain [PF00059.23, score=25.9]} {Human: ENSG00000090659, CD209, CD209 molecule, [Score=48.1, Expect=6e-06]} {Mouse: ENSMUSG00000031495, Cd209d, CD209d antigen, [Score=46.2, Expect=1e-05]; ENSMUSG00000079168, Cd209g, CD209g antigen, [Score=45.4, Expect=1e-05]} {Dmel: FBgn0040096, lectin-33A, [Score=45.8, Expect=7e-06]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.1, Expect=9e-11]} {RNA1509_35402} {RNA1310_58025} {RNA815_61888}
79. MligTC455_48656 24 0.5 Mlig455_039647

Neo: -

Age: -

0.956 - - - 0.956 - - Mlig455_039647 {REF} {Length: 1715} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=42.7]} {RNA1310_48037} {RNA815_27969}
80. MligTC455_52402 223 4.65 Mlig455_048722

Neo: -

Age: -

Region-enriched R8: 5.458/0.00000
Region-enriched R7: 3.221/0.04638

0.956 - - - - - 0.956 Mlig455_048722 {REF} {Length: 961} {TRANSSPLICED} {RNA1310_39954.1} {RNA815_19596}
81. MligTC455_12074 8 0.17 Mlig455_018818

Neo: -

Age: -

FCN3 0.955 - - - 0.955 - - Mlig455_018818 {REF} {Length: 1202} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=73.6]} {Human: ENSG00000142748, FCN3, ficolin 3, [Score=71.2, Expect=1e-13]; ENSG00000116147, TNR, tenascin R, [Score=70.1, Expect=1e-12]; ENSG00000120332, TNN, tenascin N, [Score=69.3, Expect=2e-12]; ENSG00000160339, FCN2, ficolin 2, [Score=68.9, Expect=1e-12]} {Mouse: ENSMUSG00000015829, Tnr, tenascin R, [Score=72.4, Expect=2e-13]; ENSMUSG00000026725, Tnn, tenascin N, [Score=71.2, Expect=4e-13]} {Dmel: FBgn0003326, sca, scabrous, [Score=69.3, Expect=9e-13]} {RNA1509_25025} {RNA1310_148603}
82. MligTC455_23975 87 1.82 Mlig455_004300, Mlig455_013677, Mlig455_035064, Mlig455_038062, Mlig455_041825, Mlig455_053049, Mlig455_065851, Mlig455_067880

Neo: Germline

Age: -

Region-enriched R4: 2.511/0.02468

0.955 - - 0.955 - - -

Mlig455_004300 {REF} {Length: 605} {RNA1509_56714} {RNA1310_24363} {RNA815_4579}

Mlig455_013677 {REF} {Length: 683} {RNA1509_56714} {RNA1310_23291.1} {RNA815_4579}

Mlig455_035064 {REF} {Length: 1386} {RNA1509_39040} {RNA1310_24363} {RNA815_4579}

Mlig455_038062 {REF} {Length: 204} {NoTransDecoderORF} {RNA1509_56714} {RNA1310_24363} {RNA815_4579}

Mlig455_041825 {REF} {Length: 85} {NoTransDecoderORF} {RNA1509_56714} {RNA1310_24363} {RNA815_4579}

Mlig455_053049 {REF} {Length: 466} {RNA1509_56714} {RNA1310_24363} {RNA815_4579}

Mlig455_065851 {REF} {Length: 1227} {RNA1509_56714} {RNA1310_24363} {RNA815_4579}

Mlig455_067880 {REF} {Length: 674} {RNA1509_56714} {RNA1310_23291.1} {RNA815_4579}
83. MligTC455_25545 54 1.12 Mlig455_019588

Neo: -

Age: -

CDKL1 0.955 - - 0.955 - - - Mlig455_019588 {REF} {Length: 3818} {Pfam: Protein kinase domain [PF00069.27, score=190.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=84.6]; Haspin like kinase domain [PF12330.10, score=18.1]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [Score=330, Expect=5e-112]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [Score=329, Expect=2e-111]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [Score=337, Expect=3e-115]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [Score=328, Expect=1e-111]} {Dmel: FBgn0031730, CG7236, [Score=293, Expect=3e-97]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [Score=288, Expect=4e-96]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [Score=366, Expect=2e-126]} {RNA1509_25889} {RNA1310_19262, RNA1509_25889} {RNA1509_25889, RNA815_26580}
84. MligTC455_04319 6 0.13 Mlig455_062746

Neo: -

Age: Up-Down-Down

WSCD2 0.954 - - 0.954 - - - Mlig455_062746 {REF} {Length: 1209} {Pfam: WSC domain [PF01822.21, score=51.2]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=49.3, Expect=2e-06]; ENSG00000179314, WSCD1, WSC domain containing 1, [Score=48.1, Expect=5e-06]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=51.2, Expect=3e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=58.5, Expect=1e-09]} {RNA1509_33301} {RNA1310_43331} {RNA815_19417}
85. MligTC455_07101 46 0.96 Mlig455_062761

Neo: -

Age: Down-Up-Down

POU4F1 0.954 - - - - - 0.954 Mlig455_062761 {REF} {Length: 2816} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=109.3]; Homeodomain [PF00046.31, score=67.1]; Helix-turn-helix domain [PF13560.8, score=22.0]} {Human: ENSG00000152192, POU4F1, POU class 4 homeobox 1, [RH, Score=271, Expect=7e-87]; ENSG00000151615, POU4F2, POU class 4 homeobox 2, [RH, Score=269, Expect=4e-86]; ENSG00000091010, POU4F3, POU class 4 homeobox 3, [RH, Score=267, Expect=2e-86]} {Mouse: ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [RH, Score=271, Expect=6e-87]; ENSMUSG00000031688, Pou4f2, POU domain, class 4, transcription factor 2, [RH, Score=268, Expect=3e-86]; ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [RH, Score=266, Expect=2e-86]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [RH, Score=265, Expect=3e-85]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [RH, Score=236, Expect=4e-75]} {Smed: dd_Smed_v6_15555_0_1, dd_Smed_v6_15555_0_1, [RH, Score=305, Expect=5e-101]} {RNA1509_57422} {RNA1310_8139.2} {RNA815_32659}
86. MligTC455_11476 26 0.54 Mlig455_035212

Neo: -

Age: -

0.954 - - - - - 0.954 Mlig455_035212 {REF} {Length: 1374} {RNA1310_88897} {RNA815_51066}
87. MligTC455_15663 35 0.73 Mlig455_062572

Neo: -

Age: logFC(26M/2M)=1.011

0.954 - - - 0.954 - - Mlig455_062572 {REF} {Length: 1735} {Pfam: PAN domain [PF00024.28, score=21.9]} {RNA1310_35902.2} {RNA815_33023}
88. MligTC455_40388 23 0.47 Mlig455_019615

Neo: -

Age: -

0.954 - - - 0.954 - - Mlig455_019615 {REF} {Length: 2102} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=34.2]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [Score=144, Expect=9e-37]} {RNA1310_29891} {RNA815_15562}
89. MligTC455_47997 36 0.75 Mlig455_053262, Mlig455_065031

Neo: -

Age: -

0.954 - - - 0.954 - -

Mlig455_053262 {REF} {Length: 927} {RNA1310_55950} {RNA815_42062.2}

Mlig455_065031 {REF} {Length: 926} {RNA1310_55950} {RNA815_42062.2}
90. MligTC455_30160 55 1.15 Mlig455_035128

Neo: -

Age: -

Region-enriched R2: 5.270/0.01686

TCF7L1 0.953 - - - 0.953 - - Mlig455_035128 {REF} {Length: 2946} {Pfam: HMG (high mobility group) box [PF00505.21, score=79.2]; HMG-box domain [PF09011.12, score=34.5]} {Human: ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=161, Expect=1e-42]; ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=158, Expect=7e-43]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=156, Expect=2e-41]} {Mouse: ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=161, Expect=8e-43]; ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=158, Expect=9e-44]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=155, Expect=1e-42]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=156, Expect=1e-40]} {Celegans: WBGene00004077, pop-1, [Score=108, Expect=2e-25]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=166, Expect=6e-48]} {RNA1509_46571} {RNA1310_11181} {RNA815_36690}
91. MligTC455_05507 7 0.14 Mlig455_059815

Neo: -

Age: -

DEF8 0.952 - - - 0.952 - - Mlig455_059815 {REF} {Length: 2030} {Pfam: Putative zinc-RING and/or ribbon [PF13901.8, score=76.9]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=25.5]; C1 domain [PF03107.18, score=23.2]} {Human: ENSG00000140995, DEF8, differentially expressed in FDCP 8 homolog, [Score=59.3, Expect=7e-09]} {Mouse: ENSMUSG00000001482, Def8, differentially expressed in FDCP 8, [Score=59.7, Expect=4e-09]} {Dmel: FBgn0046296, CG11534, [RH, Score=82.4, Expect=1e-16]} {Celegans: WBGene00013235, Y56A3A.16, [RH, Score=60.8, Expect=1e-09]}
92. MligTC455_11837 41 0.85 Mlig455_038844, Mlig455_061795

Neo: -

Age: -

0.952 - - 0.952 - - -

Mlig455_038844 {REF} {Length: 313} {NoTransDecoderORF} {RNA1509_39174} {RNA1310_66701.2} {RNA815_34070.1}

Mlig455_061795 {REF} {Length: 1254} {NoTransDecoderORF} {RNA1509_39174} {RNA1310_78685.1} {RNA815_46839}
93. MligTC455_12503 81 1.69 Mlig455_007611, Mlig455_007636, Mlig455_054199, Mlig455_061602, Mlig455_061615

Neo: -

Age: Down-Up-Up

0.952 - - 0.952 - - -

Mlig455_007611 {REF} {Length: 243} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_32550} {RNA1310_57270} {RNA815_14295}

Mlig455_007636 {REF} {Length: 217} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_32550} {RNA1310_57270} {RNA815_14295}

Mlig455_054199 {REF} {Length: 371} {NoTransDecoderORF} {RNA1509_38113} {RNA1310_56484.1} {RNA815_14295}

Mlig455_061602 {REF} {Length: 247} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_38113} {RNA1310_57270} {RNA815_14295}

Mlig455_061615 {REF} {Length: 234} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_38113} {RNA1310_57270} {RNA815_14295}
94. MligTC455_29586 237 4.95 Mlig455_024687, Mlig455_024712

Neo: -

Age: -

Region-specific R2: 5.384

Region-enriched R2: 6.584/0.00000

0.952 - - - 0.952 - -

Mlig455_024687 {REF} {Length: 1636} {RNA1509_26262} {RNA1310_30838} {RNA815_35621}

Mlig455_024712 {REF} {Length: 1612} {RNA1509_26262} {RNA1310_30838} {RNA815_35621}
95. MligTC455_37200 32 0.67 Mlig455_030215, Mlig455_030221, Mlig455_067995, Mlig455_067998

Neo: -

Age: -

0.952 - - - 0.952 - -

Mlig455_030215 {REF} {Length: 1088} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=23.5]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=106, Expect=1e-25]} {RNA1310_102374}

Mlig455_030221 {REF} {Length: 1980} {RNA1310_56149} {RNA815_31265}

Mlig455_067995 {REF} {Length: 792} {Pfam: SAP domain [PF02037.29, score=35.7]} {RNA1509_8096} {RNA1310_1771} {RNA815_801}

Mlig455_067998 {REF} {Length: 1295} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=24.0]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=105, Expect=2e-25]} {RNA1310_102374}
96. MligTC455_42530 41 0.86 Mlig455_064531

Neo: -

Age: -

RASL12 0.952 - - - 0.952 - - Mlig455_064531 {REF} {Length: 4677} {Pfam: Ras family [PF00071.24, score=65.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=24.9]} {Human: ENSG00000103710, RASL12, RAS like family 12, [Score=88.6, Expect=3e-20]; ENSG00000134533, RERG, RAS like estrogen regulated growth inhibitor, [Score=87.4, Expect=3e-20]} {Mouse: ENSMUSG00000092164, Rergl, RERG/RAS-like, [Score=89.4, Expect=3e-21]; ENSMUSG00000030222, Rerg, RAS-like, estrogen-regulated, growth-inhibitor, [Score=87.4, Expect=2e-20]} {Dmel: FBgn0035711, CG8519, [Score=88.6, Expect=6e-21]} {Celegans: WBGene00021811, ral-1, RAL (Ras-related GTPase) homolog, [Score=65.5, Expect=2e-12]} {Smed: dd_Smed_v6_7273_0_1, dd_Smed_v6_7273_0_1, [Score=87.8, Expect=6e-21]} {RNA1310_147102}
97. MligTC455_10128 251 5.23 Mlig455_044096

Neo: Germline

Age: logFC(26M/2M)=0.557

Region-specific R4: 6.362

Region-enriched R4: 3.908/0.00004

0.951 0.951 - - - - - Mlig455_044096 {REF} {Length: 670} {RNA1509_29277} {RNA1310_55083, RNA1509_29277} {RNA1509_29277, RNA815_31406}
98. MligTC455_24667 92 1.91 Mlig455_035642

Neo: -

Age: Down-Up-Down

KCNMA1 0.951 - - - - - 0.951 Mlig455_035642 {REF} {Length: 4504} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=96.4]; Ion transport protein [PF00520.33, score=61.2]; Ion channel [PF07885.18, score=59.0]; Ligand-gated ion channel [PF00060.28, score=21.3]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=513, Expect=5e-165]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=513, Expect=2e-166]} {Dmel: FBgn0003429, slo, slowpoke, [Score=545, Expect=2e-179]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=500, Expect=6e-162]} {Smed: dd_Smed_v6_20110_0_1, dd_Smed_v6_20110_0_1, [Score=496, Expect=1e-163]} {RNA1509_20450} {RNA1310_2582} {RNA815_1358}
99. MligTC455_33141 65 1.36 Mlig455_033449, Mlig455_040183

Neo: -

Age: Down-Up-Down

0.951 - - - - - 0.951

Mlig455_033449 {REF} {Length: 2524} {RNA1310_22116} {RNA815_34454}

Mlig455_040183 {REF} {Length: 2528} {RNA1310_22116} {RNA815_34454}
100. MligTC455_21522 150 3.13 Mlig455_023013, Mlig455_023113

Neo: Irradiation

Age: Up-Down-Down

0.95 0.950 - - - - -

Mlig455_023013 {REF} {Length: 2571} {RNA1509_42012, RNA1509_59800} {RNA1310_10648, RNA1509_42012, RNA1509_59800} {RNA1509_42012, RNA1509_59800, RNA815_16238}

Mlig455_023113 {REF} {Length: 2537} {RNA1509_42012} {RNA1310_10648} {RNA815_16238}

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