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Results for MligTC455_12793

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_12793 154 3.20 Mlig455_035462

Neo: -

Age: -

Region-enriched R2: 3.292/0.00953

CSNK1D Mlig455_035462 {REF} {Length: 2870} {Pfam: Protein kinase domain [PF00069.27, score=97.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=58.1]; Fungal protein kinase [PF17667.3, score=29.9]; Phosphotransferase enzyme family [PF01636.25, score=21.1]} {Human: ENSG00000141551, CSNK1D, casein kinase 1 delta, [RH, Score=578, Expect=0.0]; ENSG00000283900, TPTEP2-CSNK1E, TPTEP2-CSNK1E readthrough, [RH, Score=573, Expect=0.0]; ENSG00000213923, CSNK1E, casein kinase 1 epsilon, [RH, Score=573, Expect=0.0]} {Mouse: ENSMUSG00000025162, Csnk1d, casein kinase 1, delta, [RH, Score=578, Expect=0.0]; ENSMUSG00000022433, Csnk1e, casein kinase 1, epsilon, [RH, Score=574, Expect=0.0]} {Dmel: FBgn0002413, dco, discs overgrown, [RH, Score=529, Expect=0.0]} {Celegans: WBGene00002203, kin-20, Casein kinase I isoform delta, [RH, Score=499, Expect=1e-176]} {Smed: dd_Smed_v6_4561_0_1, dd_Smed_v6_4561_0_1, [RH, Score=577, Expect=0.0]} {RNA1509_19984} {RNA1310_23975} {RNA815_12595}

Cumulative graph for MligTC455_12793

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -7.512 2.389 0.03688 0.47255
RegionR2 3.292 2.389 0.00032 0.00953
RegionR3 0.841 2.389 0.38333 0.91459
RegionR4 -0.723 2.389 0.97546 1.00000
RegionR5 0.158 2.389 0.79228 1.00000
RegionR6 1.817 2.389 0.02577 0.29348
RegionR7 0.242 2.389 0.78394 1.00000
RegionR8 1.885 2.389 0.13024 0.66167

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 2.812 2.389 0.99970 1.00000
RegenerationR2 -0.36 2.389 0.55241 0.89471
RegenerationR3 1.875 2.389 0.00680 0.15025
RegenerationR4 0.367 2.389 0.61871 0.92026
RegenerationR5 0.646 2.389 0.31820 0.74199
RegenerationR6 -0.692 2.389 0.38422 0.72445
RegenerationBL -1.176 2.389 0.38584 0.75390
RegenerationTP 1.909 2.389 0.03499 0.31253


Genes with expression patterns similar to MligTC455_12793

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_12793 154 3.2 Mlig455_035462

Neo: -

Age: -

Region-enriched R2: 3.292/0.00953

CSNK1D 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_035462 {REF} {Length: 2870} {Pfam: Protein kinase domain [PF00069.27, score=97.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=58.1]; Fungal protein kinase [PF17667.3, score=29.9]; Phosphotransferase enzyme family [PF01636.25, score=21.1]} {Human: ENSG00000141551, CSNK1D, casein kinase 1 delta, [RH, Score=578, Expect=0.0]; ENSG00000283900, TPTEP2-CSNK1E, TPTEP2-CSNK1E readthrough, [RH, Score=573, Expect=0.0]; ENSG00000213923, CSNK1E, casein kinase 1 epsilon, [RH, Score=573, Expect=0.0]} {Mouse: ENSMUSG00000025162, Csnk1d, casein kinase 1, delta, [RH, Score=578, Expect=0.0]; ENSMUSG00000022433, Csnk1e, casein kinase 1, epsilon, [RH, Score=574, Expect=0.0]} {Dmel: FBgn0002413, dco, discs overgrown, [RH, Score=529, Expect=0.0]} {Celegans: WBGene00002203, kin-20, Casein kinase I isoform delta, [RH, Score=499, Expect=1e-176]} {Smed: dd_Smed_v6_4561_0_1, dd_Smed_v6_4561_0_1, [RH, Score=577, Expect=0.0]} {RNA1509_19984} {RNA1310_23975} {RNA815_12595}
2. MligTC455_36507 1422 29.63 Mlig455_038156, Mlig455_038261

Neo: -

Age: logFC(26M/2M)=-0.241

DNAI2 1.705 - - 0.753 0.952 - -

Mlig455_038156 {REF} {Length: 2699} {TRANSSPLICED} {Human: ENSG00000171595, DNAI2, dynein axonemal intermediate chain 2, [Score=534, Expect=0.0]} {Mouse: ENSMUSG00000034706, Dnaic2, dynein, axonemal, intermediate chain 2, [Score=513, Expect=1e-178]} {Dmel: FBgn0036195, Dnai2, dynein, axonemal, intermediate chain 2, [Score=386, Expect=4e-129]} {Smed: dd_Smed_v6_2644_0_1, dd_Smed_v6_2644_0_1, [Score=612, Expect=0.0]} {RNA1509_8245} {RNA1310_9583.1} {RNA815_3264}

Mlig455_038261 {REF} {Length: 2387} {TRANSSPLICED} {Human: ENSG00000171595, DNAI2, dynein axonemal intermediate chain 2, [RH, Score=756, Expect=0.0]} {Mouse: ENSMUSG00000034706, Dnaic2, dynein, axonemal, intermediate chain 2, [RH, Score=740, Expect=0.0]} {Dmel: FBgn0036195, Dnai2, dynein, axonemal, intermediate chain 2, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_2644_0_1, dd_Smed_v6_2644_0_1, [RH, Score=867, Expect=0.0]} {RNA1509_8245} {RNA1310_9583.1} {RNA815_3264}
3. MligTC455_13963 31 0.64 Mlig455_052027

Neo: -

Age: Down-Up-Down

0.987 - - - 0.987 - - Mlig455_052027 {REF} {Length: 1717} {RNA1509_48973} {RNA1310_34931} {RNA815_59614}
4. MligTC455_41226 44 0.92 Mlig455_019357, Mlig455_059122

Neo: -

Age: -

GALNT1 0.982 - - - 0.982 - -

Mlig455_019357 {REF} {Length: 1606} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=97.5]; Glycosyltransferase like family 2 [PF13641.8, score=38.9]; N-terminal domain of galactosyltransferase [PF02709.16, score=29.1]; Glycosyltransferase like family 2 [PF10111.11, score=18.5]} {Human: ENSG00000141429, GALNT1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=318, Expect=2e-103]; ENSG00000139629, GALNT6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=311, Expect=4e-100]; ENSG00000257594, GALNT4, polypeptide N-acetylgalactosaminyltransferase 4, [Score=305, Expect=3e-98]; ENSG00000259075, POC1B-GALNT4, POC1B-GALNT4 readthrough, [Score=305, Expect=3e-98]} {Mouse: ENSMUSG00000000420, Galnt1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=316, Expect=1e-102]; ENSMUSG00000037280, Galnt6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=308, Expect=9e-99]; ENSMUSG00000060988, Galnt13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=302, Expect=3e-97]} {Dmel: FBgn0050463, CG30463, [Score=345, Expect=5e-113]} {Celegans: WBGene00001630, gly-5, Polypeptide N-acetylgalactosaminyltransferase 5, [Score=350, Expect=3e-115]} {Smed: dd_Smed_v6_8580_0_1, dd_Smed_v6_8580_0_1, [Score=353, Expect=1e-117]} {RNA1310_25598} {RNA815_36943}

Mlig455_059122 {REF} {Length: 2150} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=96.4]; Glycosyltransferase like family 2 [PF13641.8, score=35.9]; N-terminal domain of galactosyltransferase [PF02709.16, score=29.5]} {Human: ENSG00000141429, GALNT1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=313, Expect=2e-101]; ENSG00000139629, GALNT6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=307, Expect=2e-98]; ENSG00000257594, GALNT4, polypeptide N-acetylgalactosaminyltransferase 4, [Score=300, Expect=6e-96]; ENSG00000259075, POC1B-GALNT4, POC1B-GALNT4 readthrough, [Score=299, Expect=7e-96]; ENSG00000144278, GALNT13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=298, Expect=1e-95]} {Mouse: ENSMUSG00000000420, Galnt1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=311, Expect=1e-100]; ENSMUSG00000037280, Galnt6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=305, Expect=1e-97]; ENSMUSG00000060988, Galnt13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=298, Expect=8e-96]; ENSMUSG00000026994, Galnt3, polypeptide N-acetylgalactosaminyltransferase 3, [Score=296, Expect=5e-94]; ENSMUSG00000026828, Galnt5, polypeptide N-acetylgalactosaminyltransferase 5, [Score=296, Expect=2e-91]} {Dmel: FBgn0050463, CG30463, [Score=340, Expect=3e-111]} {Celegans: WBGene00001630, gly-5, Polypeptide N-acetylgalactosaminyltransferase 5, [Score=344, Expect=3e-113]} {Smed: dd_Smed_v6_8580_0_1, dd_Smed_v6_8580_0_1, [Score=350, Expect=3e-116]} {RNA1310_25598} {RNA815_36943}
5. MligTC455_43002 147 3.07 Mlig455_004304

Neo: -

Age: Up-Down-Down

GLUD1 0.982 - - - 0.982 - - Mlig455_004304 {REF} {Length: 2088} {Pfam: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=134.8]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [Score=288, Expect=8e-94]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [Score=285, Expect=5e-93]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [Score=288, Expect=5e-94]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [Score=288, Expect=2e-96]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [Score=240, Expect=4e-76]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [Score=277, Expect=1e-90]} {RNA1509_18938, RNA1509_30743} {RNA1310_2661.2, RNA1509_18938} {RNA1509_18938, RNA815_713.2}
6. MligTC455_14184 23 0.48 Mlig455_026684

Neo: -

Age: -

0.981 - - - 0.981 - - Mlig455_026684 {REF} {Length: 674} {NoTransDecoderORF} {RNA1310_72508} {RNA815_40858}
7. MligTC455_42053 93 1.93 Mlig455_027261

Neo: -

Age: Down-Up-Down

0.98 - - - 0.980 - - Mlig455_027261 {REF} {Length: 1018} {NoTransDecoderORF} {RNA1509_32735} {RNA1310_29165.1} {RNA815_31830}
8. MligTC455_35943 122 2.55 Mlig455_062123

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.634

FEZF2 0.979 - - - 0.979 - - Mlig455_062123 {REF} {Length: 3163} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=87.7]; Zinc-finger double domain [PF13465.8, score=71.3]; C2H2-type zinc finger [PF13894.8, score=56.0]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=25.4]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=23.1]; C2H2-type zinc finger [PF13912.8, score=21.6]} {Human: ENSG00000153266, FEZF2, FEZ family zinc finger 2, [RH, Score=337, Expect=3e-107]; ENSG00000128610, FEZF1, FEZ family zinc finger 1, [RH, Score=330, Expect=6e-105]} {Mouse: ENSMUSG00000021743, Fezf2, Fez family zinc finger 2, [RH, Score=341, Expect=7e-109]; ENSMUSG00000029697, Fezf1, Fez family zinc finger 1, [RH, Score=330, Expect=1e-104]} {Dmel: FBgn0031375, erm, earmuff, [RH, Score=343, Expect=2e-107]} {Celegans: WBGene00012639, fezf-1, FEZ Family zinc finger protein, [RH, Score=293, Expect=5e-94]} {Smed: dd_Smed_v6_26394_0_1, dd_Smed_v6_26394_0_1, [RH, Score=287, Expect=9e-92]} {RNA1310_14572} {RNA815_32467}
9. MligTC455_42087 129 2.68 Mlig455_028171

Neo: -

Age: -

0.979 - - - 0.979 - - Mlig455_028171 {REF} {Length: 2511} {RNA1509_40406} {RNA1310_12938} {RNA815_16887}
10. MligTC455_16874 38 0.8 Mlig455_028170

Neo: -

Age: -

KCNK18 0.977 - - - 0.977 - - Mlig455_028170 {REF} {Length: 2452} {Pfam: Ion channel [PF07885.18, score=103.1]; Protein of unknown function (DUF3112) [PF11309.10, score=20.2]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [Score=96.7, Expect=1e-21]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=2e-23]} {Dmel: FBgn0033257, sand, sandman, [Score=129, Expect=2e-33]} {Celegans: WBGene00006680, twk-28, TWiK family of potassium channels, [Score=144, Expect=3e-38]} {Smed: dd_Smed_v6_17586_0_1, dd_Smed_v6_17586_0_1, [Score=270, Expect=2e-87]} {RNA1509_39975} {RNA1310_18301.1} {RNA815_12440}
11. MligTC455_17146 36 0.75 Mlig455_055993

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=1.327

0.976 - - - 0.976 - - Mlig455_055993 {REF} {Length: 1325} {RNA1310_23394.2} {RNA815_13883}
12. MligTC455_25463 163 3.39 Mlig455_001181

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.027

Region-enriched R2: 4.234/0.00772

0.976 - - - 0.976 - - Mlig455_001181 {REF} {Length: 1504} {RNA1509_58508} {RNA1310_32754} {RNA815_47065}
13. MligTC455_31901 18 0.38 Mlig455_022355

Neo: -

Age: -

0.976 - - - 0.976 - - Mlig455_022355 {REF} {Length: 541} {Pfam: PAN domain [PF00024.28, score=19.0]} {RNA1310_125793} {RNA815_23776.1}
14. MligTC455_32382 248 5.17 Mlig455_051226

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.907

0.976 - - - 0.976 - - Mlig455_051226 {REF} {Length: 6909} {RNA1509_7608} {RNA1310_3625} {RNA815_395.1}
15. MligTC455_47244 216 4.49 Mlig455_016130

Neo: -

Age: -

Region-enriched R2: 3.391/0.02151
Region-enriched R6: 2.922/0.03099

0.976 - - - 0.976 - - Mlig455_016130 {REF} {Length: 3312} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=27.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=20.5]} {Smed: dd_Smed_v6_24733_0_1, dd_Smed_v6_24733_0_1, [RH, Score=231, Expect=1e-71]} {RNA1509_41111} {RNA1310_18481.1} {RNA815_10445}
16. MligTC455_18499 24 0.5 Mlig455_012628

Neo: -

Age: -

0.975 - - - 0.975 - - Mlig455_012628 {REF} {Length: 1340} {Smed: dd_Smed_v6_500_0_1, dd_Smed_v6_500_0_1, [Score=60.5, Expect=1e-10]} {RNA1310_107419} {RNA815_46554}
17. MligTC455_19063 11283 235.06 Mlig455_029456

Neo: -

Age: logFC(26M/2M)=-0.563

MOXD1 0.975 - - - 0.975 - - Mlig455_029456 {REF} {Length: 2942} {Pfam: Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=57.0]; Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=56.7]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=83.2, Expect=5e-16]} {Mouse: ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=91.7, Expect=6e-19]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=86.3, Expect=2e-17]} {RNA1509_12910, RNA1509_22206, RNA1509_383, RNA1509_4788, RNA1509_6411} {RNA1310_17053.1, RNA1509_12910, RNA1509_22206, RNA1509_383, RNA1509_4788, RNA1509_6411} {RNA1509_12910, RNA1509_22206, RNA1509_383, RNA1509_4788, RNA1509_6411, RNA815_3799}
18. MligTC455_29045 127 2.65 Mlig455_056054

Neo: -

Age: -

Region-enriched R2: 4.858/0.00652

FZD5 0.975 - - - 0.975 - - Mlig455_056054 {REF} {Length: 3655} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=389.0]; Fz domain [PF01392.24, score=85.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=554, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [Score=561, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=516, Expect=5e-176]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=368, Expect=3e-120]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [Score=522, Expect=7e-178]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
19. MligTC455_13039 18 0.38 Mlig455_012224, Mlig455_069088

Neo: -

Age: -

0.974 - - - 0.974 - -

Mlig455_012224 {REF} {Length: 1882} {Smed: dd_Smed_v6_9937_0_1, dd_Smed_v6_9937_0_1, [Score=177, Expect=1e-50]} {RNA1310_109660}

Mlig455_069088 {REF} {Length: 2016} {Smed: dd_Smed_v6_9937_0_1, dd_Smed_v6_9937_0_1, [Score=190, Expect=2e-55]} {RNA1310_109660}
20. MligTC455_17149 83 1.73 Mlig455_042126

Neo: -

Age: -

0.974 - - - 0.974 - - Mlig455_042126 {REF} {Length: 1645} {RNA1509_55690} {RNA1310_69830} {RNA815_28343}
21. MligTC455_17804 27 0.56 Mlig455_069447

Neo: -

Age: -

0.974 - - - 0.974 - - Mlig455_069447 {REF} {Length: 955} {RNA1310_40722} {RNA815_46396}
22. MligTC455_29082 203 4.24 Mlig455_062753

Neo: -

Age: logFC(26M/2M)=-0.658

Region-enriched R2: 3.564/0.00708

VWA3B 0.974 - - - 0.974 - - Mlig455_062753 {REF} {Length: 4345} {TRANSSPLICED} {Pfam: von Willebrand factor type A domain [PF13768.8, score=82.4]; von Willebrand factor type A domain [PF00092.30, score=42.0]; von Willebrand factor type A domain [PF13519.8, score=31.6]} {Human: ENSG00000168658, VWA3B, von Willebrand factor A domain containing 3B, [RH, Score=604, Expect=0.0]} {Mouse: ENSMUSG00000050122, Vwa3b, von Willebrand factor A domain containing 3B, [RH, Score=444, Expect=2e-140]} {Smed: dd_Smed_v6_9363_0_2, dd_Smed_v6_9363_0_2, [RH, Score=920, Expect=0.0]} {RNA1509_3581} {RNA1310_1567} {RNA815_329.1}
23. MligTC455_33812 919 19.14 Mlig455_051682

Neo: -

Age: -

Region-enriched R2: 3.553/0.00065

MOXD1 0.974 - - - 0.974 - - Mlig455_051682 {REF} {Length: 2654} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=93.8]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=68.4]; Proline-rich membrane anchor 1 [PF16101.7, score=18.9]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=120, Expect=2e-28]; ENSG00000123454, DBH, dopamine beta-hydroxylase, [Score=117, Expect=2e-27]} {Mouse: ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=135, Expect=1e-33]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=129, Expect=8e-32]} {Celegans: WBGene00006541, tbh-1, Tyramine beta-hydroxylase, [Score=139, Expect=2e-35]} {Smed: dd_Smed_v6_42610_0_1, dd_Smed_v6_42610_0_1, [Score=119, Expect=1e-29]} {RNA1509_127, RNA1509_19917, RNA1509_32862, RNA1509_35753, RNA1509_41801} {RNA1310_9934.2, RNA1509_19917, RNA1509_32862, RNA1509_35753, RNA1509_41801} {RNA1509_19917, RNA1509_32862, RNA1509_35753, RNA1509_41801, RNA815_4383.1}
24. MligTC455_44186 185 3.85 Mlig455_052492

Neo: -

Age: -

0.974 - - - 0.974 - - Mlig455_052492 {REF} {Length: 959} {Pfam: Lectin C-type domain [PF00059.23, score=33.2]} {RNA1509_20946} {RNA1310_41618} {RNA815_32434}
25. MligTC455_45298 125 2.59 Mlig455_042414

Neo: Irradiation

Age: -

Region-enriched R5: 4.149/0.00000
Region-enriched R6: 2.982/0.04478

ZIC5 0.974 - - - 0.974 - - Mlig455_042414 {REF} {Length: 3878} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=62.7]; Zinc-finger double domain [PF13465.8, score=62.0]; Zic proteins zinc finger domain [PF18366.3, score=50.1]; C2H2-type zinc finger [PF13894.8, score=35.6]} {Human: ENSG00000139800, ZIC5, Zic family member 5, [RH, Score=279, Expect=4e-86]; ENSG00000152977, ZIC1, Zic family member 1, [RH, Score=275, Expect=7e-87]; ENSG00000156925, ZIC3, Zic family member 3, [RH, Score=274, Expect=1e-86]; ENSG00000043355, ZIC2, Zic family member 2, [RH, Score=273, Expect=2e-85]; ENSG00000174963, ZIC4, Zic family member 4, [RH, Score=270, Expect=7e-86]} {Mouse: ENSMUSG00000041703, Zic5, zinc finger protein of the cerebellum 5, [RH, Score=282, Expect=6e-88]; ENSMUSG00000032368, Zic1, zinc finger protein of the cerebellum 1, [RH, Score=275, Expect=4e-87]; ENSMUSG00000067860, Zic3, zinc finger protein of the cerebellum 3, [RH, Score=273, Expect=4e-86]; ENSMUSG00000061524, Zic2, zinc finger protein of the cerebellum 2, [RH, Score=273, Expect=1e-85]; ENSMUSG00000036972, Zic4, zinc finger protein of the cerebellum 4, [RH, Score=271, Expect=3e-87]} {Dmel: FBgn0003002, opa, odd paired, [RH, Score=286, Expect=9e-90]} {Celegans: WBGene00004335, ref-2, REgulator of Fusion, [Score=182, Expect=1e-53]} {Smed: dd_Smed_v6_22585_0_1, dd_Smed_v6_22585_0_1, [RH, Score=298, Expect=1e-95]} {RNA1509_20828} {RNA1310_13529.1} {RNA815_17611}
26. MligTC455_46250 250 5.22 Mlig455_061252, Mlig455_062640

Neo: -

Age: Up-Down-Down

Region-enriched R8: 3.242/0.04858

ANK3 0.974 - - - 0.974 - -

Mlig455_061252 {REF} {Length: 6298} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=515.9]; Ankyrin repeat [PF00023.32, score=428.9]; Ankyrin repeats (many copies) [PF13637.8, score=422.7]; Ankyrin repeat [PF13606.8, score=373.9]; Ankyrin repeats (many copies) [PF13857.8, score=357.7]; Ion transport protein [PF00520.33, score=32.5]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=331, Expect=3e-91]; ENSG00000029534, ANK1, ankyrin 1, [Score=323, Expect=9e-89]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=340, Expect=4e-94]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [RH, Score=1282, Expect=0.0]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=1209, Expect=0.0]} {Smed: dd_Smed_v6_21003_0_1, dd_Smed_v6_21003_0_1, [Score=1539, Expect=0.0]} {RNA1509_19181} {RNA1310_8680} {RNA815_14387}

Mlig455_062640 {REF} {Length: 5955} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=524.6]; Ankyrin repeat [PF00023.32, score=431.5]; Ankyrin repeats (many copies) [PF13637.8, score=428.3]; Ankyrin repeat [PF13606.8, score=380.8]; Ankyrin repeats (many copies) [PF13857.8, score=357.0]; Ion transport protein [PF00520.33, score=32.4]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=338, Expect=2e-93]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=345, Expect=9e-96]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [RH, Score=1318, Expect=0.0]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [RH, Score=1261, Expect=0.0]} {Smed: dd_Smed_v6_21003_0_1, dd_Smed_v6_21003_0_1, [RH, Score=1582, Expect=0.0]} {RNA1509_19181} {RNA1310_6198, RNA1509_19181} {RNA1509_19181, RNA815_14387}
27. MligTC455_50643 38 0.8 Mlig455_007952, Mlig455_008053

Neo: -

Age: -

VSX1 0.974 - - - 0.974 - -

Mlig455_007952 {REF} {Length: 1358} {Pfam: Homeodomain [PF00046.31, score=79.6]} {Human: ENSG00000100987, VSX1, visual system homeobox 1, [RH, Score=197, Expect=4e-60]; ENSG00000119614, VSX2, visual system homeobox 2, [RH, Score=196, Expect=2e-59]} {Mouse: ENSMUSG00000021239, Vsx2, visual system homeobox 2, [RH, Score=196, Expect=6e-60]; ENSMUSG00000033080, Vsx1, visual system homeobox 1, [RH, Score=195, Expect=2e-59]} {Dmel: FBgn0263512, Vsx2, Visual system homeobox 2, [RH, Score=204, Expect=3e-60]} {Celegans: WBGene00000435, ceh-10, Homeobox protein ceh-10, [RH, Score=204, Expect=2e-63]} {Smed: dd_Smed_v6_19286_0_1, dd_Smed_v6_19286_0_1, [RH, Score=211, Expect=2e-66]} {RNA1310_76393} {RNA815_51313}

Mlig455_008053 {REF} {Length: 2271} {RNA1310_76393} {RNA815_51313}
28. MligTC455_09697 52 1.08 Mlig455_009478, Mlig455_061921

Neo: -

Age: -

CD207 0.973 - - - 0.973 - -

Mlig455_009478 {REF} {Length: 1068} {Pfam: Lectin C-type domain [PF00059.23, score=39.5]} {Human: ENSG00000116031, CD207, CD207 molecule, [Score=48.5, Expect=5e-06]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=1e-13]} {RNA1310_33496.1} {RNA815_23317}

Mlig455_061921 {REF} {Length: 776} {Pfam: Lectin C-type domain [PF00059.23, score=35.3]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=69.7, Expect=4e-14]} {RNA1310_33496.1} {RNA815_23317}
29. MligTC455_24473 2936 61.17 Mlig455_051348

Neo: -

Age: -

CSMD2 0.973 - - - 0.973 - - Mlig455_051348 {REF} {Length: 18390} {Pfam: CUB domain [PF00431.22, score=95.4]; Sushi repeat (SCR repeat) [PF00084.22, score=86.7]; Tyrosine-protein kinase ephrin type A/B receptor-like [PF07699.15, score=67.5]; HYR domain [PF02494.18, score=57.6]; Calcium-binding EGF domain [PF07645.17, score=46.6]; Complement Clr-like EGF-like [PF12662.9, score=22.9]; Coagulation Factor Xa inhibitory site [PF14670.8, score=21.3]} {Human: ENSG00000121904, CSMD2, CUB and Sushi multiple domains 2, [Score=103, Expect=1e-20]} {Mouse: ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=96.7, Expect=7e-19]; ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=94.7, Expect=3e-18]; ENSMUSG00000028804, Csmd2, CUB and Sushi multiple domains 2, [Score=92.8, Expect=1e-17]} {Dmel: FBgn0031879, uif, uninflatable, [Score=212, Expect=5e-54]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=214, Expect=1e-54]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=77.4, Expect=1e-13]} {RNA1509_1720, RNA1509_23010} {RNA1310_11.1, RNA1509_1720, RNA1509_23010} {RNA1509_1720, RNA1509_23010, RNA815_7}
30. MligTC455_32383 630 13.12 Mlig455_001890, Mlig455_045019, Mlig455_069717

Neo: -

Age: logFC(26M/2M)=0.809

0.973 - - - 0.973 - -

Mlig455_001890 {REF} {Length: 5219} {Pfam: DBF zinc finger [PF07535.14, score=54.5]} {RNA1509_7608} {RNA1310_3625} {RNA815_395.1}

Mlig455_045019 {REF} {Length: 5389} {Pfam: DBF zinc finger [PF07535.14, score=49.7]} {RNA1509_7608} {RNA1310_3625} {RNA815_395.1}

Mlig455_069717 {REF} {Length: 4985} {Pfam: DBF zinc finger [PF07535.14, score=54.6]} {RNA1509_7608} {RNA1310_3625} {RNA815_395.1}
31. MligTC455_42351 126 2.62 Mlig455_014089

Neo: -

Age: Up-Down-Down

BMP1 0.973 - - - 0.973 - - Mlig455_014089 {REF} {Length: 6334} {Pfam: CUB domain [PF00431.22, score=147.3]} {Human: ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=107, Expect=7e-23]} {Mouse: ENSMUSG00000053626, Tll1, tolloid-like, [Score=97.8, Expect=3e-20]; ENSMUSG00000025013, Tll2, tolloid-like 2, [Score=95.9, Expect=1e-19]} {Dmel: FBgn0261262, CG42613, [Score=274, Expect=4e-77]} {Celegans: WBGene00002977, lev-10, LEV-10B, [Score=235, Expect=6e-65]} {Smed: dd_Smed_v6_11447_0_1, dd_Smed_v6_11447_0_1, [Score=401, Expect=2e-123]} {RNA1509_7178} {RNA1310_25466} {RNA815_477.1}
32. MligTC455_43324 71 1.47 Mlig455_041984

Neo: -

Age: -

Region-enriched R2: 6.623/0.00573

0.973 - - - 0.973 - - Mlig455_041984 {REF} {Length: 388} {NoTransDecoderORF} {RNA1509_49821} {RNA1310_52560.2} {RNA815_59873}
33. MligTC455_04694 263 5.48 Mlig455_055581

Neo: -

Age: -

Region-enriched R2: 2.810/0.00203

GATA3 0.972 - - - 0.972 - - Mlig455_055581 {REF} {Length: 1543} {Pfam: GATA zinc finger [PF00320.29, score=90.2]; TFIIB zinc-binding [PF08271.14, score=24.1]} {Human: ENSG00000107485, GATA3, GATA binding protein 3, [Score=192, Expect=4e-56]; ENSG00000179348, GATA2, GATA binding protein 2, [Score=188, Expect=5e-54]; ENSG00000136574, GATA4, GATA binding protein 4, [Score=185, Expect=3e-53]; ENSG00000285109, GATA4, GATA binding protein 4, [Score=185, Expect=3e-53]} {Mouse: ENSMUSG00000015619, Gata3, GATA binding protein 3, [Score=192, Expect=3e-56]; ENSMUSG00000015053, Gata2, GATA binding protein 2, [Score=188, Expect=3e-54]; ENSMUSG00000021944, Gata4, GATA binding protein 4, [Score=185, Expect=3e-53]} {Dmel: FBgn0003117, pnr, pannier, [Score=193, Expect=1e-55]} {Celegans: WBGene00001249, elt-1, Transcription factor elt-1, [Score=188, Expect=4e-55]} {Smed: dd_Smed_v6_8208_0_1, dd_Smed_v6_8208_0_1, [Score=193, Expect=4e-57]} {RNA1509_48614} {RNA1310_35720, RNA1509_48614} {RNA1509_48614, RNA815_57528}
34. MligTC455_40727 251 5.23 Mlig455_035865, Mlig455_035903

Neo: -

Age: logFC(26M/2M)=-0.563

0.972 - - - 0.972 - -

Mlig455_035865 {REF} {Length: 1198} {Pfam: Linker region of enhancer of mRNA-decapping protein 3 [PF16598.7, score=19.4]} {RNA1310_40952} {RNA815_53592}

Mlig455_035903 {REF} {Length: 1199} {Pfam: Linker region of enhancer of mRNA-decapping protein 3 [PF16598.7, score=19.4]} {RNA1310_40952} {RNA815_53592}
35. MligTC455_53015 462 9.61 Mlig455_046085, Mlig455_046710, Mlig455_047061

Neo: -

Age: -

0.972 - - - - 0.972 -

Mlig455_046085 {REF} {Length: 90} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_52245} {RNA1310_76980} {RNA815_21429.1}

Mlig455_046710 {REF} {Length: 707} {TRANSSPLICED} {RNA1509_35561} {RNA1310_52621} {RNA815_21429.1}

Mlig455_047061 {REF} {Length: 580} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_35561} {RNA1310_61780} {RNA815_35137}
36. MligTC455_13715 49 1.03 Mlig455_000810

Neo: -

Age: Down-Up-Down

CETN2 0.971 - - - 0.971 - - Mlig455_000810 {REF} {Length: 852} {Pfam: EF-hand domain pair [PF13499.8, score=36.4]; EF hand [PF00036.34, score=34.7]; EF-hand domain [PF13405.8, score=33.7]; EF-hand domain pair [PF13833.8, score=26.0]; EF hand [PF13202.8, score=19.9]} {Human: ENSG00000147400, CETN2, centrin 2, [Score=57.0, Expect=5e-10]; ENSG00000143933, CALM2, calmodulin 2, [Score=56.6, Expect=8e-10]; ENSG00000160014, CALM3, calmodulin 3, [Score=56.6, Expect=2e-10]; ENSG00000198668, CALM1, calmodulin 1, [Score=56.6, Expect=2e-10]; ENSG00000177143, CETN1, centrin 1, [Score=55.1, Expect=2e-09]} {Mouse: ENSMUSG00000050996, Cetn1, centrin 1, [Score=63.2, Expect=2e-12]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=58.2, Expect=5e-11]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=58.5, Expect=1e-11]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=58.2, Expect=3e-11]} {RNA1310_39411} {RNA815_27208}
37. MligTC455_18899 25 0.51 Mlig455_022106

Neo: -

Age: -

0.971 - - - 0.971 - - Mlig455_022106 {REF} {Length: 1792} {Pfam: F5/8 type C domain [PF00754.27, score=28.8]} {Smed: dd_Smed_v6_71482_0_1, dd_Smed_v6_71482_0_1, [Score=62.0, Expect=1e-11]} {RNA1310_41523} {RNA815_37841}
38. MligTC455_19064 1659 34.56 Mlig455_029479

Neo: -

Age: logFC(26M/2M)=-0.425

Region-enriched R2: 4.582/0.01945

MOXD1 0.971 - - - 0.971 - - Mlig455_029479 {REF} {Length: 2454} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=57.5]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=55.7]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=85.1, Expect=1e-16]} {Mouse: ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=95.1, Expect=5e-20]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=82.0, Expect=6e-16]} {RNA1509_10910, RNA1509_383, RNA1509_4965, RNA1509_52547, RNA1509_7121} {RNA1310_17053.1, RNA1509_10910, RNA1509_4965, RNA1509_52547, RNA1509_7121} {RNA1509_10910, RNA1509_4965, RNA1509_52547, RNA1509_7121, RNA815_3799}
39. MligTC455_39179 44 0.91 Mlig455_052012

Neo: -

Age: Down-Up-Up

TCTE3 0.971 - - - 0.971 - - Mlig455_052012 {REF} {Length: 1042} {Pfam: Tctex-1 family [PF03645.15, score=42.5]} {Human: ENSG00000184786, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=65.9, Expect=8e-13]; ENSG00000275368, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=65.9, Expect=8e-13]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [Score=61.6, Expect=1e-11]} {Smed: dd_Smed_v6_9036_0_1, dd_Smed_v6_9036_0_1, [Score=92.8, Expect=1e-23]} {RNA1509_34873} {RNA1310_34743} {RNA815_18661}
40. MligTC455_39874 143 2.98 Mlig455_049425

Neo: -

Age: -

PKDCC 0.971 - - - 0.971 - - Mlig455_049425 {REF} {Length: 3789} {Pfam: Protein-kinase domain of FAM69 [PF12260.10, score=30.6]; Protein kinase domain [PF00069.27, score=21.0]} {Human: ENSG00000162878, PKDCC, protein kinase domain containing, cytoplasmic, [RH, Score=192, Expect=4e-55]} {Mouse: ENSMUSG00000024247, Pkdcc, protein kinase domain containing, cytoplasmic, [RH, Score=180, Expect=9e-51]} {RNA1310_12305} {RNA815_19030.1}
41. MligTC455_41870 67 1.39 Mlig455_042417

Neo: -

Age: Up-Down-Up

ANGPTL1 0.971 - - - 0.971 - - Mlig455_042417 {REF} {Length: 1469} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=110.4]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=102, Expect=6e-24]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=99.8, Expect=3e-23]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=104, Expect=6e-25]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=99.4, Expect=4e-23]} {Dmel: FBgn0003326, sca, scabrous, [Score=89.4, Expect=1e-19]} {Celegans: WBGene00017013, ensh-1, [Score=55.1, Expect=2e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=73.6, Expect=1e-14]} {RNA1509_28467} {RNA1310_67810} {RNA815_18070.1}
42. MligTC455_42088 72 1.5 Mlig455_028244

Neo: -

Age: -

0.971 - - - 0.971 - - Mlig455_028244 {REF} {Length: 2632} {RNA1509_40406} {RNA1310_12938} {RNA815_16887}
43. MligTC455_45051 307 6.41 Mlig455_043687, Mlig455_043755

Neo: -

Age: -

0.971 - - - 0.971 - -

Mlig455_043687 {REF} {Length: 1460} {RNA1310_17293.1}

Mlig455_043755 {REF} {Length: 1366} {TRANSSPLICED} {RNA1310_17293.1}
44. MligTC455_12333 27 0.56 Mlig455_013978

Neo: -

Age: -

0.97 - - - 0.970 - - Mlig455_013978 {REF} {Length: 458} {RNA1310_91390} {RNA815_43195}
45. MligTC455_12334 27 0.56 Mlig455_034994

Neo: -

Age: -

0.97 - - - 0.970 - - Mlig455_034994 {REF} {Length: 779} {Pfam: WSC domain [PF01822.21, score=51.8]; PAN domain [PF00024.28, score=31.6]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=55.1, Expect=1e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=54.7, Expect=2e-08]} {RNA1310_91390} {RNA815_24291.1}
46. MligTC455_25464 185 3.85 Mlig455_001339

Neo: -

Age: -

Region-enriched R2: 4.725/0.00025

0.97 - - - 0.970 - - Mlig455_001339 {REF} {Length: 1386} {RNA1509_58508} {RNA1310_32754, RNA1509_58508} {RNA1509_58508, RNA815_47065}
47. MligTC455_40228 146 3.03 Mlig455_010654, Mlig455_010753

Neo: -

Age: logFC(26M/2M)=0.372

Region-enriched R2: 5.064/0.02014

KY 0.97 - - - 0.970 - -

Mlig455_010654 {REF} {Length: 3057} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=103, Expect=6e-22]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=113, Expect=2e-25]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=373, Expect=6e-115]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [RH, Score=347, Expect=3e-106]} {Smed: dd_Smed_v6_1846_0_1, dd_Smed_v6_1846_0_1, [Score=207, Expect=1e-55]} {RNA1509_35609} {RNA1310_6947.1} {RNA815_20684}

Mlig455_010753 {REF} {Length: 3328} {Pfam: LIM domain [PF00412.24, score=33.6]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=104, Expect=3e-22]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=114, Expect=2e-25]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=376, Expect=1e-115]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [RH, Score=353, Expect=4e-108]} {Smed: dd_Smed_v6_1846_0_1, dd_Smed_v6_1846_0_1, [Score=207, Expect=2e-55]} {RNA1509_35609} {RNA1310_6947.1, RNA1509_35609} {RNA1509_35609, RNA815_20684}
48. MligTC455_42733 190 3.96 Mlig455_060196

Neo: -

Age: logFC(26M/2M)=-0.623

SLC22A7 0.97 - - - 0.970 - - Mlig455_060196 {REF} {Length: 2722} {Pfam: Sugar (and other) transporter [PF00083.26, score=94.3]; Major Facilitator Superfamily [PF07690.18, score=70.1]} {Human: ENSG00000137204, SLC22A7, solute carrier family 22 member 7, [Score=125, Expect=3e-30]} {Mouse: ENSMUSG00000074028, Slc22a13, solute carrier family 22 (organic cation transporter), member 13, [Score=124, Expect=7e-30]; ENSMUSG00000067144, Slc22a7, solute carrier family 22 (organic anion transporter), member 7, [Score=121, Expect=3e-29]} {Dmel: FBgn0034479, CG8654, [Score=115, Expect=2e-27]} {Celegans: WBGene00019408, K05F1.6, [Score=71.6, Expect=5e-13]} {Smed: dd_Smed_v6_1159_0_1, dd_Smed_v6_1159_0_1, [Score=87.8, Expect=2e-18]} {RNA1509_11814} {RNA1310_15619.1} {RNA815_5783.2}
49. MligTC455_26253 375 7.81 Mlig455_009976

Neo: -

Age: -

FZD5 0.969 - - - 0.969 - - Mlig455_009976 {REF} {Length: 4082} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=407.2]; Fz domain [PF01392.24, score=99.7]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [RH, Score=605, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=607, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [RH, Score=402, Expect=2e-130]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [RH, Score=417, Expect=8e-139]} {Smed: dd_Smed_v6_11823_0_1, dd_Smed_v6_11823_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_25697, RNA1509_59712} {RNA1310_9946, RNA1509_25697} {RNA1509_25697, RNA815_7287}
50. MligTC455_43690 262 5.46 Mlig455_035029, Mlig455_053437

Neo: -

Age: -

Region-enriched R2: 6.108/0.00708

WSCD2 0.969 - - - 0.969 - -

Mlig455_035029 {REF} {Length: 893} {Pfam: WSC domain [PF01822.21, score=50.2]; PAN domain [PF00024.28, score=29.7]} {RNA1310_42429} {RNA815_24291.1}

Mlig455_053437 {REF} {Length: 972} {Pfam: WSC domain [PF01822.21, score=52.4]; PAN domain [PF00024.28, score=29.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=44.7, Expect=1e-05]} {RNA1310_42429} {RNA815_24291.1}
51. MligTC455_26600 111 2.32 Mlig455_000691

Neo: -

Age: logFC(26M/2M)=-0.305

Region-enriched R2: 4.160/0.03510

0.968 - - - 0.968 - - Mlig455_000691 {REF} {Length: 6281} {Smed: dd_Smed_v6_17076_0_1, dd_Smed_v6_17076_0_1, [RH, Score=214, Expect=1e-56]} {RNA1509_20580} {RNA1310_21461} {RNA815_12493}
52. MligTC455_29030 141 2.93 Mlig455_061986

Neo: -

Age: logFC(26M/2M)=-0.349

Region-enriched R2: 5.117/0.03372

FZD5 0.968 - - - 0.968 - - Mlig455_061986 {REF} {Length: 3701} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=386.1]; Fz domain [PF01392.24, score=95.9]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=582, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=586, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=545, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=388, Expect=7e-127]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [RH, Score=556, Expect=0.0]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
53. MligTC455_39180 256 5.34 Mlig455_057231

Neo: -

Age: logFC(26M/2M)=-0.449

TCTE3 0.968 - - - 0.968 - - Mlig455_057231 {REF} {Length: 1057} {Pfam: Tctex-1 family [PF03645.15, score=43.3]} {Human: ENSG00000275368, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=67.8, Expect=2e-13]; ENSG00000184786, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=67.8, Expect=2e-13]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [Score=61.2, Expect=2e-11]; ENSMUSG00000079710, Gm3448, predicted gene 3448, [Score=59.3, Expect=1e-10]; ENSMUSG00000079707, Tcte3, t-complex-associated testis expressed 3, [Score=59.3, Expect=1e-10]; ENSMUSG00000116780, Gm3417, predicted gene 3417, [Score=58.5, Expect=2e-10]} {Smed: dd_Smed_v6_9036_0_1, dd_Smed_v6_9036_0_1, [Score=92.4, Expect=2e-23]} {RNA1509_34873, RNA1509_48552} {RNA1310_34743, RNA1509_34873, RNA1509_48552} {RNA1509_34873, RNA1509_48552, RNA815_18661}
54. MligTC455_49815 254 5.29 Mlig455_034449, Mlig455_066215

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.653

0.968 - - - 0.968 - -

Mlig455_034449 {REF} {Length: 1029} {RNA1509_39560} {RNA1310_52222.2} {RNA815_27937}

Mlig455_066215 {REF} {Length: 1283} {RNA1509_39560} {RNA1310_52222.2, RNA1509_39560} {RNA1509_39560, RNA815_27937}
55. MligTC455_06165 54 1.13 Mlig455_052286

Neo: -

Age: -

Region-enriched R2: 3.737/0.02836

0.967 - - - 0.967 - - Mlig455_052286 {REF} {Length: 338} {NoTransDecoderORF} {RNA1310_6967} {RNA815_2666}
56. MligTC455_09688 16 0.32 Mlig455_020078

Neo: -

Age: -

Region-enriched R5: 3.740/0.03280

0.967 - - - 0.967 - - Mlig455_020078 {REF} {Length: 803} {Pfam: WSC domain [PF01822.21, score=60.8]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=56.6, Expect=2e-09]} {RNA1509_53783} {RNA1310_40622} {RNA815_30345}
57. MligTC455_16093 33 0.69 Mlig455_067277

Neo: -

Age: Down-Up-Up

Region-enriched R4: 4.796/0.01059

CETN2 0.967 - - - 0.967 - - Mlig455_067277 {REF} {Length: 886} {Pfam: EF-hand domain pair [PF13499.8, score=36.2]; EF hand [PF00036.34, score=36.0]; EF-hand domain [PF13405.8, score=32.4]; EF-hand domain pair [PF13833.8, score=26.0]; EF hand [PF13202.8, score=19.4]} {Human: ENSG00000147400, CETN2, centrin 2, [Score=58.9, Expect=1e-10]; ENSG00000143933, CALM2, calmodulin 2, [Score=56.6, Expect=1e-09]; ENSG00000198668, CALM1, calmodulin 1, [Score=56.6, Expect=2e-10]; ENSG00000160014, CALM3, calmodulin 3, [Score=56.6, Expect=2e-10]} {Mouse: ENSMUSG00000050996, Cetn1, centrin 1, [Score=63.5, Expect=2e-12]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=58.5, Expect=6e-11]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=58.9, Expect=2e-11]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=58.5, Expect=4e-11]} {RNA1310_39411} {RNA815_27208}
58. MligTC455_26019 350 7.3 Mlig455_031572

Neo: -

Age: logFC(26M/2M)=-0.339

EPS8 0.967 - - - - 0.967 - Mlig455_031572 {REF} {Length: 3430} {TRANSSPLICED} {Pfam: SH3 domain [PF00018.30, score=22.4]; Variant SH3 domain [PF07653.19, score=20.3]} {Human: ENSG00000151491, EPS8, epidermal growth factor receptor pathway substrate 8, [RH, Score=145, Expect=4e-37]} {Mouse: ENSMUSG00000015766, Eps8, epidermal growth factor receptor pathway substrate 8, [Score=155, Expect=2e-40]} {Dmel: FBgn0029095, aru, arouser, [RH, Score=140, Expect=7e-35]} {Celegans: WBGene00001330, eps-8, EPS (Human endocytosis) related; Epidermal growth factor receptor pathway substrate 8 splice variant A, [Score=202, Expect=2e-56]} {Smed: dd_Smed_v6_8993_0_1, dd_Smed_v6_8993_0_1, [RH, Score=76.6, Expect=1e-14]} {RNA1509_28837, RNA1509_47266, RNA1509_55389} {RNA1310_7150.2, RNA1509_28837, RNA1509_47266} {RNA1509_28837, RNA1509_47266, RNA815_2475.1}
59. MligTC455_29040 262 5.46 Mlig455_003133

Neo: -

Age: Down-Up-Down

VWA3B 0.967 - - - 0.967 - - Mlig455_003133 {REF} {Length: 4304} {TRANSSPLICED} {Pfam: von Willebrand factor type A domain [PF13768.8, score=82.5]; von Willebrand factor type A domain [PF00092.30, score=41.8]; von Willebrand factor type A domain [PF13519.8, score=31.6]} {Human: ENSG00000168658, VWA3B, von Willebrand factor A domain containing 3B, [RH, Score=608, Expect=0.0]} {Mouse: ENSMUSG00000050122, Vwa3b, von Willebrand factor A domain containing 3B, [RH, Score=446, Expect=2e-141]} {Smed: dd_Smed_v6_9363_0_2, dd_Smed_v6_9363_0_2, [RH, Score=928, Expect=0.0]} {RNA1509_3581} {RNA1310_1567} {RNA815_329.1}
60. MligTC455_32644 41 0.86 Mlig455_043770, Mlig455_043786

Neo: -

Age: -

Region-enriched R2: 6.705/0.00336

0.967 - - - 0.967 - -

Mlig455_043770 {REF} {Length: 1011} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.8, Expect=3e-11]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}

Mlig455_043786 {REF} {Length: 1348} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
61. MligTC455_36014 1671 34.81 Mlig455_004210

Neo: -

Age: Up-Up-Down

Region-enriched R2: 2.167/0.00118

PLA2G3 0.967 - - - 0.967 - - Mlig455_004210 {REF} {Length: 1631} {Pfam: Phospholipase A2 [PF05826.14, score=106.6]} {Human: ENSG00000100078, PLA2G3, phospholipase A2 group III, [RH, Score=97.4, Expect=6e-23]} {Mouse: ENSMUSG00000034579, Pla2g3, phospholipase A2, group III, [RH, Score=99.4, Expect=5e-24]} {Dmel: FBgn0030013, GIIIspla2, Phospholipase A2 group III, [RH, Score=97.8, Expect=5e-25]} {Smed: dd_Smed_v6_3851_0_2, dd_Smed_v6_3851_0_2, [RH, Score=103, Expect=4e-27]} {RNA1509_17589, RNA1509_26075, RNA1509_28230, RNA1509_8881} {RNA1310_22647, RNA1509_17589, RNA1509_26075, RNA1509_28230, RNA1509_8881} {RNA1509_17589, RNA1509_26075, RNA1509_28230, RNA1509_8881, RNA815_9445}
62. MligTC455_13468 36 0.75 Mlig455_044410, Mlig455_044445

Neo: -

Age: -

0.966 - - - 0.966 - -

Mlig455_044410 {REF} {Length: 1049} {Pfam: Dynein light chain type 1 [PF01221.20, score=56.6]; EF-hand domain pair [PF13499.8, score=29.7]; EF hand [PF00036.34, score=25.9]; EF-hand domain [PF13405.8, score=20.6]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [Score=130, Expect=9e-39]} {RNA1310_56608} {RNA815_53279}

Mlig455_044445 {REF} {Length: 1016} {Pfam: Dynein light chain type 1 [PF01221.20, score=56.6]; EF-hand domain pair [PF13499.8, score=29.7]; EF hand [PF00036.34, score=25.9]; EF-hand domain [PF13405.8, score=20.6]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [Score=130, Expect=9e-39]} {RNA1310_56608} {RNA815_53279}
63. MligTC455_14110 17 0.35 Mlig455_046797

Neo: -

Age: -

0.966 - - - 0.966 - - Mlig455_046797 {REF} {Length: 2748} {RNA1509_35160} {RNA1310_58833} {RNA815_9166}
64. MligTC455_22688 18 0.37 Mlig455_030413

Neo: -

Age: -

GRIK3 0.966 - - - 0.966 - - Mlig455_030413 {REF} {Length: 3851} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=76.0]; Ligand-gated ion channel [PF00060.28, score=51.9]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=45.7]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=158, Expect=1e-40]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=153, Expect=7e-39]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=149, Expect=7e-38]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=149, Expect=6e-38]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=148, Expect=2e-37]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=142, Expect=1e-35]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=132, Expect=1e-32]} {Smed: dd_Smed_v6_4267_0_3, dd_Smed_v6_4267_0_3, [Score=149, Expect=5e-38]} {RNA1310_20394.1} {RNA815_45848}
65. MligTC455_25242 55 1.15 Mlig455_046799, Mlig455_063518

Neo: -

Age: -

Region-enriched R2: 5.810/0.00185

DOC2B, RPH3A 0.966 - - - 0.966 - -

Mlig455_046799 {REF} {Length: 1832} {Pfam: C2 domain [PF00168.32, score=147.1]} {Human: ENSG00000272636, DOC2B, double C2 domain beta, [Score=243, Expect=3e-76]; ENSG00000272670, DOC2B, double C2 domain beta, [Score=243, Expect=3e-76]; ENSG00000089169, RPH3A, rabphilin 3A, [Score=237, Expect=3e-71]; ENSG00000149927, DOC2A, double C2 domain alpha, [Score=234, Expect=1e-72]} {Mouse: ENSMUSG00000020848, Doc2b, double C2, beta, [Score=243, Expect=3e-76]; ENSMUSG00000052301, Doc2a, double C2, alpha, [Score=239, Expect=1e-74]; ENSMUSG00000029608, Rph3a, rabphilin 3A, [Score=237, Expect=4e-71]} {Dmel: FBgn0030230, Rph, Rabphilin, [RH, Score=188, Expect=2e-55]} {Celegans: WBGene00004316, rbf-1, Rabphilin-1, [Score=216, Expect=4e-62]} {Smed: dd_Smed_v6_12977_0_1, dd_Smed_v6_12977_0_1, [Score=239, Expect=5e-73]} {RNA1310_26201} {RNA815_12702}

Mlig455_063518 {REF} {Length: 2724} {Pfam: C2 domain [PF00168.32, score=147.7]} {Human: ENSG00000089169, RPH3A, rabphilin 3A, [RH, Score=240, Expect=2e-72]} {Mouse: ENSMUSG00000029608, Rph3a, rabphilin 3A, [RH, Score=240, Expect=2e-72]} {Dmel: FBgn0030230, Rph, Rabphilin, [RH, Score=191, Expect=1e-54]} {Celegans: WBGene00004316, rbf-1, Rabphilin-1, [Score=219, Expect=4e-63]} {Smed: dd_Smed_v6_12977_0_2, dd_Smed_v6_12977_0_2, [Score=241, Expect=1e-73]} {RNA1310_26201} {RNA815_12702}
66. MligTC455_34520 250 5.2 Mlig455_027524, Mlig455_061031

Neo: -

Age: -

0.966 - - - 0.966 - -

Mlig455_027524 {REF} {Length: 2203} {RNA1509_36864} {RNA1310_46371} {RNA815_20991}

Mlig455_061031 {REF} {Length: 2568} {RNA1509_36864} {RNA1310_46371} {RNA815_20991}
67. MligTC455_36730 165 3.44 Mlig455_056961

Neo: -

Age: Up-Down-Down

0.966 - - - 0.966 - - Mlig455_056961 {REF} {Length: 4865} {Pfam: Lipoma HMGIC fusion partner-like protein [PF10242.11, score=57.3]} {RNA1310_49374} {RNA815_39552}
68. MligTC455_44187 34 0.71 Mlig455_052509

Neo: -

Age: -

0.966 - - - 0.966 - - Mlig455_052509 {REF} {Length: 883} {Pfam: Lectin C-type domain [PF00059.23, score=31.5]} {RNA1509_20946} {RNA1310_41618} {RNA815_32434}
69. MligTC455_18322 82 1.71 Mlig455_021228

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.636

0.965 - - - 0.965 - - Mlig455_021228 {REF} {Length: 3954} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=26.3]} {Smed: dd_Smed_v6_11972_0_1, dd_Smed_v6_11972_0_1, [RH, Score=229, Expect=2e-64]} {RNA1509_9124} {RNA1310_5268.1, RNA1509_9124} {RNA1509_9124, RNA815_1717.1}
70. MligTC455_22551 1093 22.77 Mlig455_000648

Neo: -

Age: -

NR5A2 0.965 - - - 0.965 - - Mlig455_000648 {REF} {Length: 2948} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=47.6]} {Human: ENSG00000116833, NR5A2, nuclear receptor subfamily 5 group A member 2, [Score=60.8, Expect=2e-09]; ENSG00000151623, NR3C2, nuclear receptor subfamily 3 group C member 2, [Score=59.3, Expect=1e-08]; ENSG00000132170, PPARG, peroxisome proliferator activated receptor gamma, [Score=58.2, Expect=1e-08]; ENSG00000119508, NR4A3, nuclear receptor subfamily 4 group A member 3, [Score=57.8, Expect=2e-08]} {Mouse: ENSMUSG00000031618, Nr3c2, nuclear receptor subfamily 3, group C, member 2, [Score=59.7, Expect=5e-09]; ENSMUSG00000024431, Nr3c1, nuclear receptor subfamily 3, group C, member 1, [Score=59.3, Expect=5e-09]; ENSMUSG00000000440, Pparg, peroxisome proliferator activated receptor gamma, [Score=58.2, Expect=1e-08]; ENSMUSG00000026826, Nr4a2, nuclear receptor subfamily 4, group A, member 2, [Score=57.4, Expect=2e-08]; ENSMUSG00000028341, Nr4a3, nuclear receptor subfamily 4, group A, member 3, [Score=57.4, Expect=2e-08]} {Dmel: FBgn0004865, Eip78C, Ecdysone-induced protein 78C, [Score=60.8, Expect=1e-09]} {Celegans: WBGene00008778, nhr-264, Nuclear Hormone Receptor family, [RH, Score=70.9, Expect=3e-13]} {Smed: dd_Smed_v6_12229_0_1, dd_Smed_v6_12229_0_1, [Score=58.9, Expect=4e-09]} {RNA1509_11892} {RNA1310_16333.2, RNA1509_11892} {RNA1509_11892, RNA815_10785}
71. MligTC455_37792 210 4.38 Mlig455_024774

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.926

Region-enriched R2: 6.055/0.00271

PKD1L2 0.965 - - - 0.965 - - Mlig455_024774 {REF} {Length: 6374} {Pfam: Polycystin cation channel [PF08016.14, score=224.6]; PLAT/LH2 domain [PF01477.25, score=66.8]; Ion transport protein [PF00520.33, score=30.8]} {Human: ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [Score=179, Expect=9e-45]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=187, Expect=3e-47]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=109, Expect=1e-23]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=187, Expect=2e-47]} {Smed: dd_Smed_v6_13975_0_1, dd_Smed_v6_13975_0_1, [Score=902, Expect=0.0]} {RNA1509_46134} {RNA1310_488} {RNA815_1711}
72. MligTC455_39097 57 1.18 Mlig455_051961

Neo: -

Age: -

Region-enriched R4: 5.550/0.02060

0.965 - - - 0.965 - - Mlig455_051961 {REF} {Length: 1972} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=65.0]} {RNA1509_13138} {RNA1310_34740} {RNA815_15663}
73. MligTC455_16293 241 5.01 Mlig455_029235

Neo: Irradiation

Age: Up-Down-Down

0.964 - - - 0.964 - - Mlig455_029235 {REF} {Length: 1804} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=61.3]} {Smed: dd_Smed_v6_14355_0_1, dd_Smed_v6_14355_0_1, [Score=81.3, Expect=8e-17]} {RNA1509_14151} {RNA1310_17181} {RNA815_7262}
74. MligTC455_19114 79 1.64 Mlig455_045107

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.813

0.964 - - - 0.964 - - Mlig455_045107 {REF} {Length: 1513} {Pfam: F5/8 type C domain [PF00754.27, score=20.0]} {RNA1509_57504} {RNA1310_27303.2} {RNA815_32964}
75. MligTC455_19455 23 0.48 Mlig455_059587

Neo: -

Age: Up-Down-Down

0.964 - - - 0.964 - - Mlig455_059587 {REF} {Length: 1356} {Pfam: FAM216B protein family [PF15107.8, score=21.6]} {RNA1310_31687} {RNA815_40824}
76. MligTC455_33922 235 4.89 Mlig455_032137

Neo: -

Age: logFC(26M/2M)=-0.421

SLC7A8 0.964 - - - 0.964 - - Mlig455_032137 {REF} {Length: 3423} {Pfam: Amino acid permease [PF13520.8, score=218.6]; Amino acid permease [PF00324.23, score=127.0]} {Human: ENSG00000092068, SLC7A8, solute carrier family 7 member 8, [Score=385, Expect=4e-127]; ENSG00000151012, SLC7A11, solute carrier family 7 member 11, [Score=384, Expect=2e-127]; ENSG00000103257, SLC7A5, solute carrier family 7 member 5, [Score=383, Expect=8e-127]; ENSG00000103064, SLC7A6, solute carrier family 7 member 6, [Score=371, Expect=7e-122]} {Mouse: ENSMUSG00000027737, Slc7a11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, [Score=416, Expect=1e-139]} {Dmel: FBgn0039487, gb, genderblind, [RH, Score=408, Expect=2e-136]} {Celegans: WBGene00000002, aat-1, Amino Acid Transporter, [Score=365, Expect=2e-120]} {Smed: dd_Smed_v6_4211_0_1, dd_Smed_v6_4211_0_1, [Score=436, Expect=2e-147]} {RNA1509_53982} {RNA1310_8199.1} {RNA815_2788}
77. MligTC455_43525 62 1.29 Mlig455_041078

Neo: -

Age: -

0.964 - - - 0.964 - - Mlig455_041078 {REF} {Length: 3896} {RNA1509_39963} {RNA1310_38466} {RNA815_23614}
78. MligTC455_13885 28 0.58 Mlig455_020919

Neo: -

Age: -

0.963 - - - 0.963 - - Mlig455_020919 {REF} {Length: 1208} {RNA1310_25040.4} {RNA815_12562.1}
79. MligTC455_17981 78 1.63 Mlig455_055277, Mlig455_055320

Neo: -

Age: -

0.963 - - - 0.963 - -

Mlig455_055277 {REF} {Length: 624} {RNA1310_72504} {RNA815_59615}

Mlig455_055320 {REF} {Length: 681} {RNA1310_72504} {RNA815_59615}
80. MligTC455_20142 488 10.17 Mlig455_036513

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.225

0.963 - - - 0.963 - - Mlig455_036513 {REF} {Length: 1074} {NoTransDecoderORF} {RNA1509_4350} {RNA1310_20554, RNA1509_4350} {RNA1509_4350, RNA815_8810.1}
81. MligTC455_40441 36 0.75 Mlig455_043401

Neo: -

Age: -

0.963 - - - 0.963 - - Mlig455_043401 {REF} {Length: 470} {NoTransDecoderORF} {RNA1509_33654} {RNA1310_22830.1} {RNA815_26998}
82. MligTC455_50769 157 3.28 Mlig455_011755, Mlig455_019899, Mlig455_047969

Neo: -

Age: -

ROR1, ROR2 0.963 - - - 0.963 - -

Mlig455_011755 {REF} {Length: 2365} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=250.7]; Protein kinase domain [PF00069.27, score=106.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=328, Expect=5e-102]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=331, Expect=7e-103]} {Dmel: FBgn0010407, Ror, [RH, Score=300, Expect=1e-93]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=228, Expect=4e-65]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=307, Expect=7e-95]} {RNA1509_34377} {RNA1310_12745} {RNA815_11383}

Mlig455_019899 {REF} {Length: 3742} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=248.8]; Protein kinase domain [PF00069.27, score=103.2]; Immunoglobulin I-set domain [PF07679.18, score=46.1]; Immunoglobulin domain [PF13927.8, score=44.2]; Immunoglobulin domain [PF00047.27, score=28.0]; Immunoglobulin domain [PF13895.8, score=27.3]; Fz domain [PF01392.24, score=27.0]; Kringle domain [PF00051.20, score=23.5]} {Human: ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [Score=393, Expect=1e-120]} {Mouse: ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=393, Expect=5e-121]} {Dmel: FBgn0010407, Ror, [RH, Score=300, Expect=3e-89]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=291, Expect=4e-84]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=439, Expect=2e-139]} {RNA1509_34377} {RNA1310_12745, RNA1509_34377} {RNA1509_34377, RNA815_11383}

Mlig455_047969 {REF} {Length: 3775} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=248.3]; Protein kinase domain [PF00069.27, score=104.3]; Immunoglobulin I-set domain [PF07679.18, score=46.2]; Immunoglobulin domain [PF13927.8, score=44.1]; Immunoglobulin domain [PF00047.27, score=28.0]; Immunoglobulin domain [PF13895.8, score=27.3]; Fz domain [PF01392.24, score=27.1]; Kringle domain [PF00051.20, score=22.3]} {Human: ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [Score=387, Expect=7e-119]} {Mouse: ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=386, Expect=1e-118]} {Dmel: FBgn0010407, Ror, [RH, Score=297, Expect=4e-88]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=285, Expect=5e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=441, Expect=3e-140]} {RNA1509_34377} {RNA1310_12745} {RNA815_11383}
83. MligTC455_43581 177 3.68 Mlig455_042725, Mlig455_042827, Mlig455_063146

Neo: -

Age: Up-Down-Down

GRIA2 0.962 - - - 0.962 - -

Mlig455_042725 {REF} {Length: 3074} {Pfam: Ligand-gated ion channel [PF00060.28, score=104.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.7]; Receptor family ligand binding region [PF01094.30, score=33.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=153, Expect=1e-37]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=149, Expect=2e-36]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=147, Expect=7e-36]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=152, Expect=2e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=148, Expect=3e-36]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=147, Expect=8e-36]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=2e-35]} {Dmel: FBgn0038837, CG3822, [Score=140, Expect=5e-34]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=253, Expect=2e-76]} {RNA1310_25150} {RNA815_13942}

Mlig455_042827 {REF} {Length: 2869} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.9]; Receptor family ligand binding region [PF01094.30, score=49.8]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.3]; Iron-containing alcohol dehydrogenase [PF13685.8, score=18.6]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=125, Expect=6e-29]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=122, Expect=5e-28]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=121, Expect=7e-28]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=120, Expect=2e-27]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=125, Expect=5e-29]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=122, Expect=4e-28]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=121, Expect=1e-27]; ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=120, Expect=1e-27]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=119, Expect=3e-27]} {Dmel: FBgn0039927, CG11155, [Score=127, Expect=7e-30]} {Celegans: WBGene00001612, glr-1, Glutamate receptor 1, [Score=103, Expect=1e-22]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=217, Expect=2e-63]} {RNA1310_25150} {RNA815_13942}

Mlig455_063146 {REF} {Length: 2444} {Pfam: Receptor family ligand binding region [PF01094.30, score=35.8]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=82.4, Expect=1e-16]} {RNA1310_25150} {RNA815_13999}
84. MligTC455_50335 2763 57.56 Mlig455_069700

Neo: -

Age: -

Region-enriched R2: 4.743/0.00005

HBG2 0.962 - - - 0.962 - - Mlig455_069700 {REF} {Length: 1017} {Pfam: Globin [PF00042.24, score=69.5]} {Human: ENSG00000196565, HBG2, hemoglobin subunit gamma 2, [RH, Score=49.7, Expect=8e-08]; ENSG00000284931, AC104389.5, novel protein, [RH, Score=47.4, Expect=7e-07]} {RNA1509_8100} {RNA1310_38363} {RNA815_18105}
85. MligTC455_16729 75 1.57 Mlig455_013762

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.685/0.03582

0.961 - - - 0.961 - - Mlig455_013762 {REF} {Length: 2706} {Pfam: Glycine rich protein [PF12810.9, score=24.7]; PAN domain [PF00024.28, score=18.7]} {RNA1310_22079} {RNA815_24304}
86. MligTC455_17568 33 0.68 Mlig455_059349, Mlig455_065584

Neo: -

Age: -

0.961 - - - 0.961 - -

Mlig455_059349 {REF} {Length: 1132} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}

Mlig455_065584 {REF} {Length: 1132} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}
87. MligTC455_46446 44 0.92 Mlig455_064208

Neo: -

Age: -

0.961 - - - 0.961 - - Mlig455_064208 {REF} {Length: 608} {RNA1509_14730} {RNA1310_29088} {RNA815_18139}
88. MligTC455_13682 42 0.87 Mlig455_030673

Neo: -

Age: -

0.96 - - - 0.960 - - Mlig455_030673 {REF} {Length: 2472} {Pfam: gag-polyprotein putative aspartyl protease [PF13975.8, score=21.9]} {RNA1509_51609} {RNA1310_3461} {RNA815_16498}
89. MligTC455_14842 21 0.45 Mlig455_041074

Neo: -

Age: -

0.96 - - - 0.960 - - Mlig455_041074 {REF} {Length: 1383} {RNA1310_60383} {RNA815_48502}
90. MligTC455_17084 3912 81.51 Mlig455_013175, Mlig455_045995

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.971

CA12 0.96 - - - 0.960 - -

Mlig455_013175 {REF} {Length: 1735} {Pfam: Eukaryotic-type carbonic anhydrase [PF00194.23, score=186.3]} {Human: ENSG00000074410, CA12, carbonic anhydrase 12, [Score=126, Expect=5e-33]; ENSG00000168748, CA7, carbonic anhydrase 7, [Score=121, Expect=7e-32]} {Mouse: ENSMUSG00000032373, Car12, carbonic anhydrase 12, [Score=133, Expect=1e-35]} {Dmel: FBgn0027844, CAH1, Carbonic anhydrase 1, [Score=105, Expect=2e-26]} {Celegans: WBGene00000283, cah-5, Putative carbonic anhydrase 5, [Score=87.4, Expect=2e-19]} {Smed: dd_Smed_v6_11683_0_1, dd_Smed_v6_11683_0_1, [RH, Score=167, Expect=4e-49]} {RNA1509_10777, RNA1509_21098} {RNA1310_14884.1, RNA1509_10777} {RNA1509_10777, RNA815_8568.1}

Mlig455_045995 {REF} {Length: 1770} {Pfam: Eukaryotic-type carbonic anhydrase [PF00194.23, score=184.2]} {Human: ENSG00000074410, CA12, carbonic anhydrase 12, [Score=125, Expect=8e-33]; ENSG00000168748, CA7, carbonic anhydrase 7, [Score=121, Expect=6e-32]} {Mouse: ENSMUSG00000032373, Car12, carbonic anhydrase 12, [Score=132, Expect=2e-35]} {Dmel: FBgn0038956, CG5379, [Score=106, Expect=4e-26]} {Celegans: WBGene00000283, cah-5, Putative carbonic anhydrase 5, [Score=87.8, Expect=2e-19]} {Smed: dd_Smed_v6_11683_0_1, dd_Smed_v6_11683_0_1, [RH, Score=171, Expect=6e-51]} {RNA1509_10449, RNA1509_21098, RNA1509_31212, RNA1509_48169} {RNA1310_14884.1, RNA1509_10449, RNA1509_21098, RNA1509_31212, RNA1509_48169} {RNA1509_10449, RNA1509_21098, RNA1509_31212, RNA1509_48169, RNA815_8568.1}
91. MligTC455_18579 143 2.97 Mlig455_047208, Mlig455_048469

Neo: -

Age: -

GRIK2, GRIK3 0.96 - - - 0.960 - -

Mlig455_047208 {REF} {Length: 5413} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=92.5]; Ligand-gated ion channel [PF00060.28, score=84.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=49.2]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=194, Expect=2e-50]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=193, Expect=5e-50]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=192, Expect=2e-49]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=192, Expect=2e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=191, Expect=3e-49]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=194, Expect=1e-50]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=194, Expect=3e-50]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=191, Expect=2e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=191, Expect=2e-49]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=188, Expect=2e-48]} {Dmel: FBgn0038837, CG3822, [Score=185, Expect=9e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=200, Expect=7e-53]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=341, Expect=5e-106]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}

Mlig455_048469 {REF} {Length: 3740} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=95.9]; Ligand-gated ion channel [PF00060.28, score=82.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=51.5]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=190, Expect=6e-50]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=187, Expect=5e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=185, Expect=3e-48]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=184, Expect=1e-47]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=189, Expect=7e-50]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=187, Expect=6e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=185, Expect=2e-48]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=183, Expect=9e-48]} {Dmel: FBgn0038837, CG3822, [Score=183, Expect=4e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=183, Expect=3e-48]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=338, Expect=6e-108]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}
92. MligTC455_25080 26 0.53 Mlig455_003599

Neo: -

Age: -

0.96 - - - 0.960 - - Mlig455_003599 {REF} {Length: 5206} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=49.2]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [Score=50.8, Expect=1e-07]} {RNA1509_27878} {RNA1310_28023} {RNA815_19588}
93. MligTC455_44612 24 0.49 Mlig455_006206, Mlig455_059294

Neo: -

Age: -

0.96 - - - 0.960 - -

Mlig455_006206 {REF} {Length: 506} {NoTransDecoderORF} {RNA1509_43593} {RNA1310_56719} {RNA815_29718}

Mlig455_059294 {REF} {Length: 1181} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=66.2, Expect=3e-13]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
94. MligTC455_46880 44 0.91 Mlig455_046271

Neo: -

Age: -

IAH1 0.96 - - - 0.960 - - Mlig455_046271 {REF} {Length: 1061} {Pfam: GDSL-like Lipase/Acylhydrolase family [PF13472.8, score=75.8]; GDSL-like Lipase/Acylhydrolase [PF00657.24, score=32.0]} {Human: ENSG00000134330, IAH1, isoamyl acetate hydrolyzing esterase 1 (putative), [Score=138, Expect=2e-39]} {Mouse: ENSMUSG00000062054, Iah1, isoamyl acetate-hydrolyzing esterase 1 homolog, [Score=121, Expect=4e-33]} {Smed: dd_Smed_v6_6241_0_1, dd_Smed_v6_6241_0_1, [Score=111, Expect=8e-30]} {RNA1310_130726}
95. MligTC455_50685 443 9.22 Mlig455_008930

Neo: -

Age: Up-Down-Down

LRRK2 0.96 - - - 0.960 - - Mlig455_008930 {REF} {Length: 12042} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=151.5]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=75.1]; TIR domain [PF13676.8, score=67.0]; Ras family [PF00071.24, score=44.4]; Leucine rich repeat [PF13855.8, score=39.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=24.7]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=158, Expect=1e-37]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=161, Expect=9e-39]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=146, Expect=3e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=122, Expect=5e-27]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=714, Expect=0.0]} {RNA1509_2407, RNA1509_24338, RNA1509_49350} {RNA1310_77.1, RNA1509_2407, RNA1509_24338, RNA1509_49350} {RNA1509_2407, RNA1509_24338, RNA1509_49350, RNA815_489}
96. MligTC455_54117 68 1.41 Mlig455_035190

Neo: -

Age: -

0.96 - - - 0.960 - - Mlig455_035190 {REF} {Length: 2042} {Pfam: WSC domain [PF01822.21, score=51.2]; PAN domain [PF00024.28, score=28.9]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=8e-06]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=51.6, Expect=2e-07]} {RNA1509_45595} {RNA1310_44717} {RNA815_32019}
97. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 0.96 - - - 0.960 - - Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
98. MligTC455_02868 46 0.96 Mlig455_039256

Neo: -

Age: -

0.959 - - - 0.959 - - Mlig455_039256 {REF} {Length: 483} {NoTransDecoderORF} {RNA1310_63888} {RNA815_2549.2}
99. MligTC455_08853 22 0.45 Mlig455_068998

Neo: -

Age: -

0.959 - - - 0.959 - - Mlig455_068998 {REF} {Length: 1981} {Pfam: Glycine rich protein [PF12810.9, score=35.1]} {RNA1310_75162} {RNA815_38988}
100. MligTC455_09830 66 1.37 Mlig455_040902

Neo: -

Age: -

0.958 - - - 0.958 - - Mlig455_040902 {REF} {Length: 1141} {RNA1310_66500} {RNA815_46507}

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