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Results for MligTC455_12824

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_12824 21 0.44 Mlig455_015782, Mlig455_045748

Neo: -

Age: -

NPY1R

Mlig455_015782 {REF} {Length: 771} {NoTransDecoderORF} {RNA1310_145549}

Mlig455_045748 {REF} {Length: 3703} {tRNA: Val(CAC),pseudo, score=23.6} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=128.8]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=27.1]} {Human: ENSG00000164128, NPY1R, neuropeptide Y receptor Y1, [Score=125, Expect=2e-31]} {Mouse: ENSMUSG00000036437, Npy1r, neuropeptide Y receptor Y1, [Score=124, Expect=3e-31]; ENSMUSG00000048337, Npy4r, neuropeptide Y receptor Y4, [Score=123, Expect=4e-31]; ENSMUSG00000028004, Npy2r, neuropeptide Y receptor Y2, [Score=119, Expect=2e-29]} {Dmel: FBgn0037408, NPFR, Neuropeptide F receptor, [Score=161, Expect=2e-44]} {Celegans: WBGene00016110, npr-11, Putative neuropeptide Y receptor 11, [Score=137, Expect=4e-36]} {Smed: dd_Smed_v6_16725_0_1, dd_Smed_v6_16725_0_1, [Score=228, Expect=7e-70]} {RNA1509_45595} {RNA1310_56759} {RNA815_43101}

Cumulative graph for MligTC455_12824

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.551 0.791 0.99975 1.00000
RegionR2 4.823 0.791 0.74767 1.00000
RegionR3 -0.786 0.791 0.99975 1.00000
RegionR4 -1.238 0.791 0.89530 1.00000
RegionR5 -1.162 0.791 0.99999 1.00000
RegionR6 -0.741 0.791 0.99975 1.00000
RegionR7 -0.212 0.791 0.99980 1.00000
RegionR8 -0.134 0.791 0.99985 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.988 0.791 0.99988 1.00000
RegenerationR2 1.062 0.791 0.17148 0.61064
RegenerationR3 3.812 0.791 0.55670 0.88709
RegenerationR4 0.585 0.791 0.96828 1.00000
RegenerationR5 2.052 0.791 0.46758 0.84084
RegenerationR6 0.702 0.791 1.00000 1.00000
RegenerationBL 0.608 0.791 1.00000 1.00000
RegenerationTP 0.357 0.791 1.00000 1.00000


Genes with expression patterns similar to MligTC455_12824

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_12824 21 0.44 Mlig455_015782, Mlig455_045748

Neo: -

Age: -

NPY1R 3 1.000 - - - 1.000 1.000

Mlig455_015782 {REF} {Length: 771} {NoTransDecoderORF} {RNA1310_145549}

Mlig455_045748 {REF} {Length: 3703} {tRNA: Val(CAC),pseudo, score=23.6} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=128.8]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=27.1]} {Human: ENSG00000164128, NPY1R, neuropeptide Y receptor Y1, [Score=125, Expect=2e-31]} {Mouse: ENSMUSG00000036437, Npy1r, neuropeptide Y receptor Y1, [Score=124, Expect=3e-31]; ENSMUSG00000048337, Npy4r, neuropeptide Y receptor Y4, [Score=123, Expect=4e-31]; ENSMUSG00000028004, Npy2r, neuropeptide Y receptor Y2, [Score=119, Expect=2e-29]} {Dmel: FBgn0037408, NPFR, Neuropeptide F receptor, [Score=161, Expect=2e-44]} {Celegans: WBGene00016110, npr-11, Putative neuropeptide Y receptor 11, [Score=137, Expect=4e-36]} {Smed: dd_Smed_v6_16725_0_1, dd_Smed_v6_16725_0_1, [Score=228, Expect=7e-70]} {RNA1509_45595} {RNA1310_56759} {RNA815_43101}
2. MligTC455_40905 53 1.1 Mlig455_002794, Mlig455_002809

Neo: -

Age: -

CHL1 2.85 0.891 - - - 0.988 0.971

Mlig455_002794 {REF} {Length: 4845} {Pfam: Immunoglobulin domain [PF13927.8, score=205.6]; Immunoglobulin I-set domain [PF07679.18, score=151.2]; Immunoglobulin domain [PF00047.27, score=122.8]; Immunoglobulin domain [PF13895.8, score=109.6]; Fibronectin type III domain [PF00041.23, score=98.8]; Immunoglobulin V-set domain [PF07686.19, score=65.4]; Immunoglobulin domain [PF18452.3, score=21.7]} {Human: ENSG00000134121, CHL1, cell adhesion molecule L1 like, [RH, Score=340, Expect=1e-96]} {Mouse: ENSMUSG00000031391, L1cam, L1 cell adhesion molecule, [RH, Score=339, Expect=2e-96]; ENSMUSG00000030077, Chl1, cell adhesion molecule L1-like, [RH, Score=335, Expect=4e-95]} {Dmel: FBgn0264975, Nrg, Neuroglian, [Score=358, Expect=2e-103]} {Celegans: WBGene00002243, lad-2, Immunoglobulin domain-containing protein Y54G2A.25; L1 CAM ADhesion molecule homolog; LAD-2 long isoform, [Score=287, Expect=1e-79]} {Smed: dd_Smed_v6_1916_0_1, dd_Smed_v6_1916_0_1, [Score=486, Expect=3e-148]} {RNA1310_42673}

Mlig455_002809 {REF} {Length: 4785} {Pfam: Immunoglobulin domain [PF13927.8, score=155.8]; Immunoglobulin I-set domain [PF07679.18, score=111.7]; Fibronectin type III domain [PF00041.23, score=99.0]; Immunoglobulin domain [PF00047.27, score=90.9]; Immunoglobulin domain [PF13895.8, score=77.2]; Immunoglobulin V-set domain [PF07686.19, score=38.0]} {Human: ENSG00000134121, CHL1, cell adhesion molecule L1 like, [Score=292, Expect=8e-81]; ENSG00000163531, NFASC, neurofascin, [Score=290, Expect=4e-80]} {Mouse: ENSMUSG00000031391, L1cam, L1 cell adhesion molecule, [Score=294, Expect=2e-81]; ENSMUSG00000026442, Nfasc, neurofascin, [Score=290, Expect=2e-80]; ENSMUSG00000030077, Chl1, cell adhesion molecule L1-like, [Score=285, Expect=2e-78]; ENSMUSG00000020598, Nrcam, neuronal cell adhesion molecule, [Score=282, Expect=7e-78]} {Dmel: FBgn0264975, Nrg, Neuroglian, [Score=315, Expect=1e-88]} {Celegans: WBGene00002243, lad-2, Immunoglobulin domain-containing protein Y54G2A.25; L1 CAM ADhesion molecule homolog; LAD-2 long isoform, [Score=251, Expect=9e-68]} {Smed: dd_Smed_v6_1916_0_1, dd_Smed_v6_1916_0_1, [Score=441, Expect=4e-132]} {RNA1310_42673}
3. MligTC455_24951 220 4.58 Mlig455_052169

Neo: -

Age: -

Region-specific R2: 4.554

Region-enriched R2: 4.264/0.00008

Regeneration-downregulated R2: -1.743

Regeneration-depleted R2: -1.743

CCDC169 2.833 0.983 - - - 0.935 0.915 Mlig455_052169 {REF} {Length: 1369} {Pfam: Domain of unknown function (DUF4600) [PF15372.8, score=97.2]} {Human: ENSG00000242715, CCDC169, coiled-coil domain containing 169, [RH, Score=82.8, Expect=6e-19]} {Mouse: ENSMUSG00000048655, Ccdc169, coiled-coil domain containing 169, [RH, Score=94.0, Expect=3e-23]} {Smed: dd_Smed_v6_12011_0_1, dd_Smed_v6_12011_0_1, [RH, Score=207, Expect=9e-68]} {RNA1509_8270} {RNA1310_23029} {RNA815_11545}
4. MligTC455_14829 56 1.17 Mlig455_053237

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.599

Region-enriched R2: 3.828/0.03404

SSUH2 2.814 0.973 - - - 0.952 0.889 Mlig455_053237 {REF} {Length: 1420} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=156, Expect=2e-43]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=117, Expect=2e-29]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=87.4, Expect=9e-19]} {RNA1509_46058} {RNA1310_5028.1} {RNA815_5650}
5. MligTC455_47704 106 2.21 Mlig455_032247

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.432

WSCD2 2.798 0.971 - - - 0.977 0.850 Mlig455_032247 {REF} {Length: 2305} {Pfam: WSC domain [PF01822.21, score=58.4]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=54.7, Expect=1e-07]; ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.8, Expect=5e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=56.6, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=63.9, Expect=1e-10]} {RNA1509_59284} {RNA1310_13567} {RNA815_27780}
6. MligTC455_24952 637 13.28 Mlig455_054178, Mlig455_060727

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.165

Region-enriched R2: 3.160/0.00003

Regeneration-downregulated BL: -4.774

Regeneration-depleted BL: -4.774

CCDC169 2.797 0.972 - - - 0.954 0.871

Mlig455_054178 {REF} {Length: 1390} {Pfam: Domain of unknown function (DUF4600) [PF15372.8, score=97.2]} {Human: ENSG00000242715, CCDC169, coiled-coil domain containing 169, [RH, Score=82.8, Expect=6e-19]} {Mouse: ENSMUSG00000048655, Ccdc169, coiled-coil domain containing 169, [RH, Score=94.0, Expect=3e-23]} {Smed: dd_Smed_v6_12011_0_1, dd_Smed_v6_12011_0_1, [RH, Score=207, Expect=9e-68]} {RNA1509_8270} {RNA1310_23029} {RNA815_11545}

Mlig455_060727 {REF} {Length: 1391} {Pfam: Domain of unknown function (DUF4600) [PF15372.8, score=97.2]} {Human: ENSG00000242715, CCDC169, coiled-coil domain containing 169, [RH, Score=82.8, Expect=6e-19]} {Mouse: ENSMUSG00000048655, Ccdc169, coiled-coil domain containing 169, [RH, Score=94.0, Expect=3e-23]} {Smed: dd_Smed_v6_12011_0_1, dd_Smed_v6_12011_0_1, [RH, Score=207, Expect=9e-68]} {RNA1509_8270} {RNA1310_23029, RNA1509_8270} {RNA1509_8270, RNA815_11545}
7. MligTC455_43557 362 7.55 Mlig455_059172, Mlig455_065527

Neo: -

Age: Down-Down-Up

Region-specific R2: 6.284

Region-enriched R2: 5.832/0.00001

ANKRD63 2.788 0.954 - - - 0.903 0.931

Mlig455_059172 {REF} {Length: 1739} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.2]; Ankyrin repeats (many copies) [PF13637.8, score=42.6]; Ankyrin repeat [PF13606.8, score=27.6]; Ankyrin repeats (many copies) [PF13857.8, score=27.1]; Ankyrin repeat [PF00023.32, score=25.9]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [Score=68.2, Expect=7e-12]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [Score=67.4, Expect=7e-12]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=49.3, Expect=7e-06]} {Celegans: WBGene00011240, R11A8.7, Ankyrin repeat and KH domain-containing protein R11A8.7, [Score=49.3, Expect=4e-06]} {Smed: dd_Smed_v6_10280_0_1, dd_Smed_v6_10280_0_1, [Score=81.3, Expect=1e-16]} {RNA1310_44826} {RNA815_62096}

Mlig455_065527 {REF} {Length: 2998} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=52.3]; Ankyrin repeats (many copies) [PF13637.8, score=42.0]; Ankyrin repeats (many copies) [PF13857.8, score=26.7]; Ankyrin repeat [PF00023.32, score=26.0]; Ankyrin repeat [PF13606.8, score=22.6]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [Score=68.2, Expect=7e-12]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [Score=68.2, Expect=6e-12]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=50.1, Expect=5e-06]} {Celegans: WBGene00011240, R11A8.7, Ankyrin repeat and KH domain-containing protein R11A8.7, [Score=50.4, Expect=2e-06]} {Smed: dd_Smed_v6_10280_0_1, dd_Smed_v6_10280_0_1, [Score=80.9, Expect=2e-16]} {RNA1509_30872} {RNA1310_44826} {RNA815_62096}
8. MligTC455_52507 60 1.26 Mlig455_016440

Neo: -

Age: -

Region-enriched R2: 5.871/0.01204

2.772 0.906 - - - 0.907 0.959 Mlig455_016440 {REF} {Length: 1576} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1310_98267}
9. MligTC455_35802 114 2.38 Mlig455_051876, Mlig455_051902, Mlig455_053140

Neo: -

Age: -

CACNA2D1 2.767 0.809 - - - 0.993 0.965

Mlig455_051876 {REF} {Length: 3144} {Pfam: Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=89.1]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=84.7, Expect=2e-16]} {RNA1509_55590} {RNA1310_60852} {RNA815_15380}

Mlig455_051902 {REF} {Length: 4662} {Pfam: VWA N-terminal [PF08399.13, score=90.4]; Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=87.6]; von Willebrand factor type A domain [PF00092.30, score=38.6]; Cache domain [PF02743.20, score=27.5]; von Willebrand factor type A domain [PF13519.8, score=26.5]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [RH, Score=326, Expect=8e-94]} {Mouse: ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [RH, Score=326, Expect=7e-94]} {Dmel: FBgn0261041, stj, straightjacket, [Score=229, Expect=7e-61]} {Celegans: WBGene00006772, unc-36, Voltage-dependent calcium channel unc-36, [Score=141, Expect=9e-34]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [Score=153, Expect=1e-37]} {RNA1509_55590} {RNA1310_7325.1, RNA1509_55590} {RNA1509_55590, RNA815_14878}

Mlig455_053140 {REF} {Length: 3265} {Pfam: Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=87.9]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=87.0, Expect=8e-17]} {Mouse: ENSMUSG00000021991, Cacna2d3, calcium channel, voltage-dependent, alpha2/delta subunit 3, [Score=50.4, Expect=9e-06]} {RNA1509_55590} {RNA1310_7325.1} {RNA815_14878}
10. MligTC455_54282 74 1.54 Mlig455_020191

Neo: -

Age: -

2.75 0.928 - - - 0.858 0.964 Mlig455_020191 {REF} {Length: 937} {RNA1509_48973} {RNA1310_40738.2} {RNA815_31898}
11. MligTC455_33636 175 3.64 Mlig455_027209, Mlig455_050659

Neo: -

Age: logFC(26M/2M)=-0.416

Region-enriched R2: 3.904/0.00709
Region-enriched R3: 2.835/0.03879

CHRNA10 2.712 0.820 - - - 0.933 0.959

Mlig455_027209 {REF} {Length: 1614} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=99.8]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=74.0]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=152, Expect=1e-40]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=150, Expect=8e-40]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=149, Expect=2e-39]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=149, Expect=2e-39]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=148, Expect=6e-39]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=150, Expect=3e-40]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=150, Expect=5e-40]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=144, Expect=5e-38]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=133, Expect=1e-33]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=142, Expect=3e-37]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=142, Expect=3e-37]} {RNA1310_19147.1} {RNA815_8553.1}

Mlig455_050659 {REF} {Length: 1670} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=93.6]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=69.9]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=148, Expect=2e-39]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=144, Expect=1e-37]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=141, Expect=1e-36]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=148, Expect=1e-39]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=141, Expect=9e-37]} {Dmel: FBgn0004118, nAChRbeta2, nicotinic Acetylcholine Receptor beta2, [Score=134, Expect=4e-34]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=144, Expect=7e-38]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=141, Expect=6e-37]} {RNA1310_19147.1} {RNA815_8553.1}
12. MligTC455_53546 130 2.72 Mlig455_013326, Mlig455_013334

Neo: -

Age: -

Region-enriched R2: 6.753/0.01892

MMP9 2.689 0.775 - - - 0.952 0.962

Mlig455_013326 {REF} {Length: 1449} {Pfam: Fibronectin type II domain [PF00040.21, score=92.5]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=87.8, Expect=3e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=82.4, Expect=1e-16]; ENSMUSG00000031740, Mmp2, matrix metallopeptidase 2, [RH, Score=78.6, Expect=2e-15]} {Smed: dd_Smed_v6_14558_0_1, dd_Smed_v6_14558_0_1, [RH, Score=138, Expect=3e-38]} {RNA1310_38631} {RNA815_51136}

Mlig455_013334 {REF} {Length: 1398} {Pfam: Fibronectin type II domain [PF00040.21, score=92.1]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=89.4, Expect=1e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=84.0, Expect=4e-17]} {Smed: dd_Smed_v6_12601_0_1, dd_Smed_v6_12601_0_1, [RH, Score=140, Expect=2e-38]} {RNA1310_38631} {RNA815_51136}
13. MligTC455_15546 141 2.93 Mlig455_021744

Neo: -

Age: -

2.685 0.978 - - - 0.837 0.870 Mlig455_021744 {REF} {Length: 1839} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=60.5]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=26.5]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=51.2, Expect=1e-06]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=72.0, Expect=3e-13]} {Celegans: WBGene00020586, frpr-18, FLP-2 receptor; FMRFamide Peptide Receptor family, [Score=69.3, Expect=2e-12]} {Smed: dd_Smed_v6_25364_0_1, dd_Smed_v6_25364_0_1, [RH, Score=197, Expect=7e-59]} {RNA1310_26850} {RNA815_17444}
14. MligTC455_50927 254 5.29 Mlig455_070541, Mlig455_070562

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.296

Region-enriched R2: 7.883/0.00008
Region-enriched R3: 4.441/0.03979

FZD4 2.674 0.900 - - - 0.818 0.956

Mlig455_070541 {REF} {Length: 3522} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=471, Expect=6e-159]} {RNA1509_15834} {RNA1310_3800, RNA1509_15834} {RNA1509_15834, RNA815_19571}

Mlig455_070562 {REF} {Length: 3527} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=2e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=470, Expect=8e-159]} {RNA1509_15834} {RNA1310_3800} {RNA815_19571}
15. MligTC455_19248 238 4.95 Mlig455_036051

Neo: -

Age: -

Region-enriched R2: 8.870/0.00000

2.658 0.807 - - - 0.891 0.960 Mlig455_036051 {REF} {Length: 807} {RNA1509_57448} {RNA1310_51394} {RNA815_26076}
16. MligTC455_47393 241 5.03 Mlig455_008718, Mlig455_063579

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.683/0.00849

CALM2 2.657 0.784 - - - 0.913 0.960

Mlig455_008718 {REF} {Length: 1727} {Pfam: EF hand [PF00036.34, score=99.3]; EF-hand domain pair [PF13499.8, score=95.1]; EF-hand domain [PF13405.8, score=86.1]; EF-hand domain pair [PF13833.8, score=76.8]; EF hand [PF13202.8, score=75.3]; EF-hand domain [PF14658.8, score=46.0]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.9]; EF-hand domain [PF08976.13, score=23.4]; Uncharacterised protein family (UPF0154) [PF03672.15, score=18.7]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=108, Expect=4e-30]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=4e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=4e-30]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-30]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=108, Expect=2e-30]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=1e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-30]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-30]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=114, Expect=8e-33]} {RNA1310_33847.1} {RNA815_17211}

Mlig455_063579 {REF} {Length: 2562} {Pfam: EF hand [PF00036.34, score=95.8]; EF-hand domain pair [PF13499.8, score=92.8]; EF-hand domain [PF13405.8, score=82.9]; EF-hand domain pair [PF13833.8, score=74.4]; EF hand [PF13202.8, score=72.2]; EF-hand domain [PF14658.8, score=43.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.6]; EF-hand domain [PF08976.13, score=21.4]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=111, Expect=7e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=3e-29]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=3e-29]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=111, Expect=7e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-29]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-29]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=9e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-29]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-29]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=111, Expect=9e-31]} {RNA1310_12431.1} {RNA815_17211}
17. MligTC455_16907 87 1.82 Mlig455_008705

Neo: -

Age: Down-Up-Down

SLC17A8 2.645 0.748 - - - 0.961 0.936 Mlig455_008705 {REF} {Length: 1949} {Pfam: Major Facilitator Superfamily [PF07690.18, score=37.9]; SOCE-associated regulatory factor of calcium homoeostasis [PF06682.14, score=19.6]} {Human: ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [Score=213, Expect=1e-65]; ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [Score=212, Expect=1e-64]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [Score=208, Expect=6e-64]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [Score=215, Expect=1e-67]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [Score=211, Expect=1e-64]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [Score=207, Expect=4e-63]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=196, Expect=1e-58]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [Score=189, Expect=1e-56]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [Score=234, Expect=3e-73]} {RNA1509_38152} {RNA1310_19607.1} {RNA815_14894}
18. MligTC455_15467 225 4.69 Mlig455_000546

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.857

Region-enriched R2: 5.997/0.00105

2.637 0.815 - - - 0.960 0.862 Mlig455_000546 {REF} {Length: 844} {Pfam: Pancreatic hormone peptide [PF00159.20, score=42.9]} {Smed: dd_Smed_v6_16946_0_1, dd_Smed_v6_16946_0_1, [Score=39.7, Expect=1e-05]} {RNA1310_53697} {RNA815_26198}
19. MligTC455_34925 183 3.82 Mlig455_012715

Neo: -

Age: -

CDKL1 2.603 0.773 - - - 0.960 0.870 Mlig455_012715 {REF} {Length: 2370} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=250.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.6]; RIO1 family [PF01163.24, score=23.0]; ABC1 atypical kinase-like domain [PF03109.18, score=20.8]; Haspin like kinase domain [PF12330.10, score=20.4]; Kinase-like [PF14531.8, score=19.4]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=437, Expect=3e-153]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=424, Expect=2e-147]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=437, Expect=2e-153]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=432, Expect=2e-151]} {Dmel: FBgn0031730, CG7236, [RH, Score=384, Expect=3e-131]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=388, Expect=3e-132]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=472, Expect=5e-167]} {RNA1509_44617} {RNA1310_15038, RNA1509_44617} {RNA1509_44617, RNA815_6379}
20. MligTC455_54202 381 7.94 Mlig455_006349

Neo: -

Age: logFC(26M/2M)=0.343

Region-specific R2: 5.916

Region-enriched R2: 5.229/0.00037

MYH6 2.579 0.966 - - - 0.806 0.807 Mlig455_006349 {REF} {Length: 6943} {Pfam: Myosin head (motor domain) [PF00063.23, score=929.0]; Myosin tail [PF01576.21, score=591.7]; Myosin N-terminal SH3-like domain [PF02736.21, score=60.7]; Crescentin protein [PF19220.2, score=26.4]; Autophagy protein 16 (ATG16) [PF08614.13, score=20.3]; Macoilin family [PF09726.11, score=18.3]} {Human: ENSG00000197616, MYH6, myosin heavy chain 6, [RH, Score=2075, Expect=0.0]; ENSG00000092054, MYH7, myosin heavy chain 7, [RH, Score=2066, Expect=0.0]; ENSG00000125414, MYH2, myosin heavy chain 2, [RH, Score=2021, Expect=0.0]; ENSG00000109061, MYH1, myosin heavy chain 1, [RH, Score=2013, Expect=0.0]; ENSG00000133020, MYH8, myosin heavy chain 8, [RH, Score=2007, Expect=0.0]; ENSG00000264424, MYH4, myosin heavy chain 4, [RH, Score=1993, Expect=0.0]; ENSG00000109063, MYH3, myosin heavy chain 3, [RH, Score=1974, Expect=0.0]} {Mouse: ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [RH, Score=2076, Expect=0.0]; ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [RH, Score=2063, Expect=0.0]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [RH, Score=2041, Expect=0.0]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [RH, Score=2018, Expect=0.0]; ENSMUSG00000055775, Myh8, myosin, heavy polypeptide 8, skeletal muscle, perinatal, [RH, Score=2015, Expect=0.0]; ENSMUSG00000033196, Myh2, myosin, heavy polypeptide 2, skeletal muscle, adult, [RH, Score=2009, Expect=0.0]; ENSMUSG00000020908, Myh3, myosin, heavy polypeptide 3, skeletal muscle, embryonic, [RH, Score=1981, Expect=0.0]; ENSMUSG00000060180, Myh13, myosin, heavy polypeptide 13, skeletal muscle, [RH, Score=1979, Expect=0.0]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [RH, Score=2100, Expect=0.0]} {Celegans: WBGene00019064, myo-5, MYOsin heavy chain structural genes, [RH, Score=1996, Expect=0.0]} {Smed: dd_Smed_v6_579_0_1, dd_Smed_v6_579_0_1, [RH, Score=2705, Expect=0.0]} {RNA1509_16048, RNA1509_54239, RNA1509_55838} {RNA1310_1388, RNA1509_16048, RNA1509_54239, RNA1509_55838} {RNA1509_16048, RNA1509_54239, RNA1509_55838, RNA815_129.1}
21. MligTC455_52813 47 0.99 Mlig455_045013

Neo: -

Age: logFC(26M/2M)=1.210

CNTN2 2.547 0.719 - - - 0.959 0.869 Mlig455_045013 {REF} {Length: 3626} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=57.7]; Immunoglobulin domain [PF13927.8, score=52.5]; Immunoglobulin domain [PF13895.8, score=40.3]; Immunoglobulin domain [PF00047.27, score=40.1]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=25.8]} {Human: ENSG00000184144, CNTN2, contactin 2, [Score=59.3, Expect=2e-08]} {Mouse: ENSMUSG00000053024, Cntn2, contactin 2, [Score=57.4, Expect=5e-08]; ENSMUSG00000061751, Kalrn, kalirin, RhoGEF kinase, [Score=55.5, Expect=2e-07]} {Dmel: FBgn0264975, Nrg, Neuroglian, [Score=55.1, Expect=2e-07]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [RH, Score=99.4, Expect=2e-22]} {RNA1509_60115} {RNA1310_31768} {RNA815_18728}
22. MligTC455_40051 36 0.76 Mlig455_025990

Neo: -

Age: logFC(26M/2M)=-0.633

PRKCE 1.988 0.991 - - - 0.997 - Mlig455_025990 {REF} {Length: 2622} {Pfam: Protein kinase domain [PF00069.27, score=102.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=69.5]; Kinase-like [PF14531.8, score=19.5]} {Human: ENSG00000171132, PRKCE, protein kinase C epsilon, [Score=84.3, Expect=1e-16]} {Mouse: ENSMUSG00000045038, Prkce, protein kinase C, epsilon, [Score=82.0, Expect=5e-16]} {Dmel: FBgn0283472, S6k, Ribosomal protein S6 kinase, [Score=79.0, Expect=2e-15]} {Celegans: WBGene00009793, pkn-1, Protein Kinase N (PKN) homolog, [Score=73.2, Expect=2e-13]} {Smed: dd_Smed_v6_8010_0_1, dd_Smed_v6_8010_0_1, [Score=77.8, Expect=4e-15]} {RNA1509_36146} {RNA1310_24732} {RNA815_64704}
23. MligTC455_23961 12 0.24 Mlig455_001329

Neo: -

Age: -

SLC6A1 1.975 - - - - 0.992 0.983 Mlig455_001329 {REF} {Length: 2800} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=486.0]} {Human: ENSG00000157103, SLC6A1, solute carrier family 6 member 1, [Score=378, Expect=3e-123]; ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=370, Expect=9e-118]} {Mouse: ENSMUSG00000030310, Slc6a1, solute carrier family 6 (neurotransmitter transporter, GABA), member 1, [Score=377, Expect=3e-123]; ENSMUSG00000030108, Slc6a13, solute carrier family 6 (neurotransmitter transporter, GABA), member 13, [Score=370, Expect=2e-120]; ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=369, Expect=1e-117]; ENSMUSG00000030109, Slc6a12, solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12, [Score=360, Expect=3e-116]} {Dmel: FBgn0034136, DAT, Dopamine transporter, [Score=356, Expect=1e-114]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=340, Expect=7e-109]} {Smed: dd_Smed_v6_8169_0_1, dd_Smed_v6_8169_0_1, [Score=350, Expect=8e-113]} {RNA1509_32034} {RNA1310_45592} {RNA815_60993}
24. MligTC455_15134 15 0.31 Mlig455_000804

Neo: -

Age: -

CNGA3 1.972 1.000 - - - 0.972 - Mlig455_000804 {REF} {Length: 2294} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=62.8]; Ion transport protein [PF00520.33, score=39.4]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [Score=351, Expect=2e-113]; ENSG00000198515, CNGA1, cyclic nucleotide gated channel alpha 1, [Score=344, Expect=2e-110]; ENSG00000183862, CNGA2, cyclic nucleotide gated channel alpha 2, [Score=340, Expect=2e-109]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [Score=352, Expect=9e-115]; ENSMUSG00000067220, Cnga1, cyclic nucleotide gated channel alpha 1, [Score=342, Expect=7e-110]; ENSMUSG00000005864, Cnga2, cyclic nucleotide gated channel alpha 2, [Score=338, Expect=9e-109]} {Dmel: FBgn0259145, CG42260, [Score=463, Expect=1e-153]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [Score=281, Expect=1e-86]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [Score=343, Expect=2e-111]} {RNA1310_120793} {RNA815_25814}
25. MligTC455_14519 25 0.51 Mlig455_005304

Neo: -

Age: -

1.97 1.000 - - - 0.970 - Mlig455_005304 {REF} {Length: 1686} {RNA1509_3030} {RNA1310_65512} {RNA815_48423}
26. MligTC455_15253 11 0.22 Mlig455_010266

Neo: -

Age: -

1.963 - - - - 0.997 0.966 Mlig455_010266 {REF} {Length: 252} {NoTransDecoderORF} {RNA815_48483}
27. MligTC455_31463 20 0.42 Mlig455_057169

Neo: -

Age: -

1.958 1.000 - - - 0.958 - Mlig455_057169 {REF} {Length: 1647} {Pfam: Methyltransferase FkbM domain [PF05050.14, score=39.0]} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=82.4, Expect=3e-18]} {RNA1509_6604} {RNA1310_43619} {RNA815_6128.2}
28. MligTC455_25412 199 4.15 Mlig455_008720, Mlig455_063581

Neo: -

Age: -

Region-enriched R2: 7.484/0.00035

CNBD2 1.956 0.971 - - - 0.985 -

Mlig455_008720 {REF} {Length: 2602} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=82.1]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [Score=52.4, Expect=3e-06]} {Smed: dd_Smed_v6_13623_0_1, dd_Smed_v6_13623_0_1, [Score=241, Expect=1e-69]} {RNA1509_50931} {RNA1310_3304} {RNA815_12767}

Mlig455_063581 {REF} {Length: 2668} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=82.3]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [Score=52.4, Expect=3e-06]} {Smed: dd_Smed_v6_13623_0_1, dd_Smed_v6_13623_0_1, [Score=241, Expect=7e-70]} {RNA1509_50931} {RNA1310_3304} {RNA815_12767}
29. MligTC455_14598 52 1.07 Mlig455_058970

Neo: -

Age: -

1.954 - - - - 0.993 0.961 Mlig455_058970 {REF} {Length: 1038} {RNA1310_39570} {RNA815_52309}
30. MligTC455_53937 44 0.92 Mlig455_021975, Mlig455_022028

Neo: -

Age: -

1.954 0.979 - - - 0.975 -

Mlig455_021975 {REF} {Length: 631} {NoTransDecoderORF} {RNA1310_130902}

Mlig455_022028 {REF} {Length: 192} {NoTransDecoderORF} {RNA1310_130902}
31. MligTC455_27785 115 2.39 Mlig455_001141

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.796

HMCN2 1.951 1.000 - - - 0.951 - Mlig455_001141 {REF} {Length: 2156} {Pfam: von Willebrand factor type A domain [PF13519.8, score=54.7]; von Willebrand factor type A domain [PF13768.8, score=30.6]} {Human: ENSG00000148357, HMCN2, hemicentin 2, [Score=81.3, Expect=2e-15]} {Mouse: ENSMUSG00000007030, Vwa7, von Willebrand factor A domain containing 7, [Score=79.0, Expect=6e-15]; ENSMUSG00000055632, Hmcn2, hemicentin 2, [Score=77.8, Expect=2e-14]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=96.3, Expect=1e-20]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=79.7, Expect=2e-15]} {RNA1509_38050} {RNA1310_19586} {RNA815_17693}
32. MligTC455_18161 771 16.05 Mlig455_031626, Mlig455_048205

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.318/0.00160

1.95 0.977 - - - 0.973 -

Mlig455_031626 {REF} {Length: 835} {TRANSSPLICED} {RNA1509_48514} {RNA1310_56583, RNA1509_48514} {RNA1509_48514, RNA815_34758}

Mlig455_048205 {REF} {Length: 651} {RNA1509_48514} {RNA1310_56583} {RNA815_34758}
33. MligTC455_45039 168 3.49 Mlig455_040482, Mlig455_040487

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.332/0.02336

1.95 1.000 - - - - 0.950

Mlig455_040482 {REF} {Length: 1774} {RNA1310_20941} {RNA815_45079}

Mlig455_040487 {REF} {Length: 5763} {tRNA: Val(CAC),pseudo, score=20.2} {Celegans: WBGene00022195, Y71H2B.5, [Score=146, Expect=8e-36]} {Smed: dd_Smed_v6_16438_0_2, dd_Smed_v6_16438_0_2, [Score=188, Expect=1e-49]} {RNA1509_21228} {RNA1310_20941} {RNA815_45079}
34. MligTC455_09224 21 0.43 Mlig455_038078

Neo: -

Age: -

1.949 1.000 - - - - 0.949 Mlig455_038078 {REF} {Length: 771} {Pfam: PAN domain [PF00024.28, score=28.0]} {RNA1509_46267} {RNA1310_51656} {RNA815_32275.1}
35. MligTC455_03731 113 2.35 Mlig455_066791

Neo: -

Age: -

1.946 0.968 - - - 0.978 - Mlig455_066791 {REF} {Length: 1679} {Smed: dd_Smed_v6_13648_0_1, dd_Smed_v6_13648_0_1, [RH, Score=79.7, Expect=2e-16]} {RNA1509_58026} {RNA1310_23180, RNA1509_58026} {RNA1509_58026, RNA815_34008}
36. MligTC455_25928 181 3.78 Mlig455_006534, Mlig455_006538, Mlig455_006649, Mlig455_006700

Neo: -

Age: logFC(26M/2M)=-0.528

Region-specific R2: 7.256

Region-enriched R2: 5.788/0.02697

1.944 - - - - 0.998 0.946

Mlig455_006534 {REF} {Length: 689} {RNA1509_22927} {RNA1310_81957.1} {RNA815_41771.2}

Mlig455_006538 {REF} {Length: 1691} {RNA1509_12380} {RNA1310_164.2} {RNA815_19957}

Mlig455_006649 {REF} {Length: 829} {RNA1509_22927} {RNA1310_81957.1} {RNA815_41771.2}

Mlig455_006700 {REF} {Length: 750} {RNA1509_22927} {RNA1310_81957.2} {RNA815_41771.2}
37. MligTC455_15329 22 0.47 Mlig455_060498

Neo: -

Age: -

1.938 - - - - 0.977 0.961 Mlig455_060498 {REF} {Length: 1186} {Pfam: PAN domain [PF00024.28, score=18.9]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=63.9, Expect=4e-12]} {RNA1310_37660} {RNA815_17816.1}
38. MligTC455_46188 25 0.51 Mlig455_039664, Mlig455_039727

Neo: -

Age: -

1.938 - - - - 0.994 0.944

Mlig455_039664 {REF} {Length: 1353}

Mlig455_039727 {REF} {Length: 1348}
39. MligTC455_52493 6 0.13 Mlig455_058213

Neo: -

Age: -

1.935 0.985 - - - 0.950 - Mlig455_058213 {REF} {Length: 1454} {Smed: dd_Smed_v6_25969_0_1, dd_Smed_v6_25969_0_1, [Score=79.0, Expect=3e-16]} {RNA1310_119010}
40. MligTC455_38355 110 2.29 Mlig455_039715, Mlig455_039769

Neo: -

Age: -

KCNB2 1.934 - - - - 0.999 0.935

Mlig455_039715 {REF} {Length: 3883} {Pfam: Ion transport protein [PF00520.33, score=114.4]; BTB/POZ domain [PF02214.24, score=75.0]; Ion channel [PF07885.18, score=43.6]} {Human: ENSG00000182674, KCNB2, potassium voltage-gated channel subfamily B member 2, [Score=218, Expect=3e-60]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=213, Expect=2e-60]; ENSG00000158445, KCNB1, potassium voltage-gated channel subfamily B member 1, [Score=213, Expect=7e-59]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=210, Expect=2e-59]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=209, Expect=7e-59]} {Mouse: ENSMUSG00000092083, Kcnb2, potassium voltage gated channel, Shab-related subfamily, member 2, [Score=219, Expect=5e-61]; ENSMUSG00000050556, Kcnb1, potassium voltage gated channel, Shab-related subfamily, member 1, [Score=218, Expect=1e-60]; ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=214, Expect=8e-61]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=213, Expect=6e-60]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=230, Expect=8e-67]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=236, Expect=3e-69]} {Smed: dd_Smed_v6_11886_0_1, dd_Smed_v6_11886_0_1, [RH, Score=592, Expect=0.0]} {RNA1509_22940} {RNA1310_17926} {RNA815_8687.1}

Mlig455_039769 {REF} {Length: 4176} {Pfam: Ion transport protein [PF00520.33, score=116.7]; BTB/POZ domain [PF02214.24, score=75.0]; Ion channel [PF07885.18, score=43.6]; Polycystin cation channel [PF08016.14, score=20.7]} {Human: ENSG00000182674, KCNB2, potassium voltage-gated channel subfamily B member 2, [Score=219, Expect=8e-61]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=216, Expect=2e-61]; ENSG00000158445, KCNB1, potassium voltage-gated channel subfamily B member 1, [Score=215, Expect=2e-59]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=213, Expect=2e-60]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=213, Expect=4e-60]; ENSG00000131398, KCNC3, potassium voltage-gated channel subfamily C member 3, [Score=210, Expect=4e-58]} {Mouse: ENSMUSG00000092083, Kcnb2, potassium voltage gated channel, Shab-related subfamily, member 2, [Score=221, Expect=2e-61]; ENSMUSG00000050556, Kcnb1, potassium voltage gated channel, Shab-related subfamily, member 1, [Score=219, Expect=4e-61]; ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=216, Expect=6e-62]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=215, Expect=6e-61]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [Score=211, Expect=1e-58]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=231, Expect=2e-67]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=239, Expect=2e-70]} {Smed: dd_Smed_v6_11886_0_1, dd_Smed_v6_11886_0_1, [RH, Score=595, Expect=0.0]} {RNA1509_22940} {RNA1310_17926} {RNA815_8687.1}
41. MligTC455_48064 23 0.48 Mlig455_061550

Neo: -

Age: -

1.931 - - - - 0.988 0.943 Mlig455_061550 {REF} {Length: 860} {RNA1310_88363} {RNA815_47885}
42. MligTC455_08774 25 0.53 Mlig455_001889

Neo: -

Age: Up-Down-Down

HCRTR2 1.93 - - - - 0.958 0.972 Mlig455_001889 {REF} {Length: 3436} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=160.6]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=30.4]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=24.1]} {Human: ENSG00000137252, HCRTR2, hypocretin receptor 2, [RH, Score=215, Expect=2e-63]} {Mouse: ENSMUSG00000032360, Hcrtr2, hypocretin (orexin) receptor 2, [RH, Score=212, Expect=1e-62]} {Dmel: FBgn0038874, ETHR, [Score=142, Expect=6e-37]} {Celegans: WBGene00013974, npr-9, Galanin-like G-protein coupled receptor npr-9, [Score=116, Expect=6e-28]} {Smed: dd_Smed_v6_22624_0_1, dd_Smed_v6_22624_0_1, [RH, Score=202, Expect=1e-59]} {RNA1310_31833} {RNA815_15909}
43. MligTC455_52746 33 0.7 Mlig455_036774

Neo: -

Age: -

1.926 - - - - 0.963 0.963 Mlig455_036774 {REF} {Length: 1992} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=90.0]} {Smed: dd_Smed_v6_16274_0_1, dd_Smed_v6_16274_0_1, [Score=77.4, Expect=7e-15]} {RNA1310_26715} {RNA815_32348}
44. MligTC455_33442 39 0.81 Mlig455_039767

Neo: -

Age: -

1.92 0.982 - - - 0.938 - Mlig455_039767 {REF} {Length: 1975} {RNA1310_42391}
45. MligTC455_29412 46 0.96 Mlig455_000627, Mlig455_008268, Mlig455_040614

Neo: -

Age: Up-Down-Up

1.919 - - - - 0.981 0.938

Mlig455_000627 {REF} {Length: 1331} {RNA1310_62571} {RNA815_30942}

Mlig455_008268 {REF} {Length: 1779} {RNA1509_47298} {RNA1310_98344} {RNA815_10804.1}

Mlig455_040614 {REF} {Length: 1016}
46. MligTC455_40065 58 1.22 Mlig455_069280

Neo: -

Age: Up-Down-Up

1.917 - - - - 0.958 0.959 Mlig455_069280 {REF} {Length: 3092} {Pfam: Coiled-coil domain-containing protein 154 [PF15450.8, score=35.7]; Apolipoprotein A1/A4/E domain [PF01442.20, score=19.3]} {Smed: dd_Smed_v6_10236_0_1, dd_Smed_v6_10236_0_1, [Score=236, Expect=1e-67]} {RNA1509_48196} {RNA1310_30411, RNA1509_48196} {RNA1509_48196, RNA815_45200}
47. MligTC455_48128 18 0.37 Mlig455_052326

Neo: -

Age: -

1.914 0.972 - - - 0.942 - Mlig455_052326 {REF} {Length: 3582} {RNA1310_42908} {RNA815_22744}
48. MligTC455_46502 168 3.5 Mlig455_010557

Neo: -

Age: -

1.913 0.925 - - - 0.988 - Mlig455_010557 {REF} {Length: 557} {Pfam: HalX domain [PF08663.12, score=24.3]} {RNA1509_57107} {RNA1310_80026, RNA1509_57107} {RNA1509_57107, RNA815_41799}
49. MligTC455_16847 1240 25.83 Mlig455_051898, Mlig455_053146

Neo: -

Age: Down-Up-Down

Region-specific R2: 5.478

Region-enriched R2: 5.690/0.00000

PRSS33 1.913 - - - - 0.945 0.968

Mlig455_051898 {REF} {Length: 1360} {Pfam: Trypsin [PF00089.28, score=189.8]; Domain of unknown function (DUF1986) [PF09342.13, score=27.3]; Trypsin-like peptidase domain [PF13365.8, score=26.9]} {Human: ENSG00000103355, PRSS33, serine protease 33, [Score=159, Expect=4e-46]} {Mouse: ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=153, Expect=9e-41]; ENSMUSG00000037129, Tmprss13, transmembrane protease, serine 13, [Score=150, Expect=2e-40]; ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [Score=148, Expect=6e-39]; ENSMUSG00000022857, Tmprss15, transmembrane protease, serine 15, [Score=147, Expect=2e-38]} {Dmel: FBgn0036287, CG10663, [Score=146, Expect=1e-38]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [Score=124, Expect=6e-31]} {Smed: dd_Smed_v6_10267_0_1, dd_Smed_v6_10267_0_1, [Score=178, Expect=4e-53]} {RNA1509_29335} {RNA1310_23561} {RNA815_9840}

Mlig455_053146 {REF} {Length: 1448} {Pfam: Trypsin [PF00089.28, score=189.8]; Domain of unknown function (DUF1986) [PF09342.13, score=27.3]; Trypsin-like peptidase domain [PF13365.8, score=26.9]} {Human: ENSG00000103355, PRSS33, serine protease 33, [Score=159, Expect=4e-46]} {Mouse: ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=153, Expect=9e-41]; ENSMUSG00000037129, Tmprss13, transmembrane protease, serine 13, [Score=150, Expect=2e-40]; ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [Score=148, Expect=6e-39]; ENSMUSG00000022857, Tmprss15, transmembrane protease, serine 15, [Score=147, Expect=2e-38]} {Dmel: FBgn0036287, CG10663, [Score=146, Expect=1e-38]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [Score=124, Expect=6e-31]} {Smed: dd_Smed_v6_10267_0_1, dd_Smed_v6_10267_0_1, [Score=178, Expect=4e-53]} {RNA1509_26566, RNA1509_29335} {RNA1310_23561, RNA1509_26566, RNA1509_29335} {RNA1509_26566, RNA1509_29335, RNA815_9840}
50. MligTC455_15726 270 5.63 Mlig455_031204

Neo: -

Age: -

Region-enriched R2: 6.820/0.00015

ADAMTS18 1.911 0.978 - - - 0.933 - Mlig455_031204 {REF} {Length: 2405} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=77.6]; Metallo-peptidase family M12 [PF13688.8, score=52.5]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=45.6]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=41.4]; ADAM cysteine-rich domain [PF17771.3, score=40.0]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=30.9]; Astacin (Peptidase family M12A) [PF01400.26, score=19.3]} {Human: ENSG00000140873, ADAMTS18, ADAM metallopeptidase with thrombospondin type 1 motif 18, [Score=90.9, Expect=1e-18]} {Mouse: ENSMUSG00000049538, Adamts16, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16, [Score=90.1, Expect=1e-18]; ENSMUSG00000053399, Adamts18, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18, [Score=89.7, Expect=2e-18]} {Dmel: FBgn0034903, sona, sol narae, [RH, Score=114, Expect=7e-27]} {Celegans: WBGene00003248, mig-17, ADAM family mig-17, [RH, Score=100, Expect=2e-22]} {RNA1509_42775} {RNA1310_19585.1, RNA1509_42775} {RNA1509_42775, RNA815_17997}
51. MligTC455_19249 90 1.86 Mlig455_054092

Neo: -

Age: Down-Up-Up

Region-enriched R2: 7.298/0.00139

1.911 - - - - 0.972 0.939 Mlig455_054092 {REF} {Length: 667} {TRANSSPLICED} {RNA1509_57448} {RNA1310_51394, RNA1509_57448} {RNA1509_57448, RNA815_26076}
52. MligTC455_32422 37 0.78 Mlig455_031348

Neo: -

Age: -

CHRNA6 1.91 0.995 - - - 0.915 - Mlig455_031348 {REF} {Length: 1659} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=69.7]} {Human: ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=61.6, Expect=5e-10]; ENSG00000160716, CHRNB2, cholinergic receptor nicotinic beta 2 subunit, [Score=61.2, Expect=8e-10]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=61.2, Expect=5e-10]; ENSMUSG00000027950, Chrnb2, cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal), [Score=60.8, Expect=8e-10]; ENSMUSG00000055026, Gabrg3, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3, [Score=58.5, Expect=4e-09]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [Score=48.5, Expect=4e-06]} {Celegans: WBGene00000057, acr-18, AcetylCholine Receptor; Acetylcholine receptor, one of nine alpha a7-like nicotinic acetylcholine receptor subunits (58.6 kD) (Acr-18), [Score=63.5, Expect=5e-11]} {Smed: dd_Smed_v6_30253_0_1, dd_Smed_v6_30253_0_1, [Score=59.3, Expect=6e-10]} {RNA1310_61084} {RNA815_48984}
53. MligTC455_19079 218 4.54 Mlig455_008746, Mlig455_008760

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.705

Region-enriched R2: 6.864/0.00152

1.91 - - - - 0.952 0.958

Mlig455_008746 {REF} {Length: 652} {RNA1310_75395.1} {RNA815_42524}

Mlig455_008760 {REF} {Length: 1051} {RNA1310_75395.1} {RNA815_42524}
54. MligTC455_12438 17 0.35 Mlig455_009594

Neo: -

Age: -

1.909 - - - - 0.984 0.925 Mlig455_009594 {REF} {Length: 2044} {RNA1310_39190} {RNA815_29274}
55. MligTC455_13165 181 3.77 Mlig455_018648

Neo: -

Age: -

Region-specific R2: 6.131

Region-enriched R2: 4.463/0.01828

Regeneration-downregulated R2: -3.253

Regeneration-depleted R2: -3.253

1.909 0.933 - - - 0.976 - Mlig455_018648 {REF} {Length: 1920} {TRANSSPLICED} {Pfam: FAD dependent oxidoreductase [PF01266.26, score=209.8]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=21.6]; FAD binding domain [PF01494.21, score=20.4]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=19.9]; FAD binding domain [PF00890.26, score=18.9]} {Mouse: ENSMUSG00000033624, Pdpr, pyruvate dehydrogenase phosphatase regulatory subunit, [Score=51.6, Expect=2e-06]} {Smed: dd_Smed_v6_5776_0_1, dd_Smed_v6_5776_0_1, [RH, Score=246, Expect=2e-77]} {RNA1509_25789} {RNA1310_15994} {RNA815_21830}
56. MligTC455_38775 266 5.54 Mlig455_066758, Mlig455_069705

Neo: -

Age: -

Region-specific R2: 6.147

Region-enriched R2: 5.505/0.02411

WNT6 1.908 - - - - 0.981 0.927

Mlig455_066758 {REF} {Length: 2739} {Pfam: wnt family [PF00110.21, score=158.2]} {Human: ENSG00000115596, WNT6, Wnt family member 6, [Score=77.4, Expect=9e-15]; ENSG00000134245, WNT2B, Wnt family member 2B, [Score=74.3, Expect=1e-13]} {Mouse: ENSMUSG00000033227, Wnt6, wingless-type MMTV integration site family, member 6, [Score=74.3, Expect=6e-14]; ENSMUSG00000027840, Wnt2b, wingless-type MMTV integration site family, member 2B, [Score=74.3, Expect=9e-14]} {Dmel: FBgn0031902, Wnt6, Wnt oncogene analog 6, [Score=70.9, Expect=9e-13]} {Celegans: WBGene00000857, cwn-1, [Score=73.9, Expect=4e-14]} {Smed: dd_Smed_v6_13487_0_1, dd_Smed_v6_13487_0_1, [Score=71.2, Expect=3e-13]} {RNA1509_23528} {RNA1310_12823.2} {RNA815_8552}

Mlig455_069705 {REF} {Length: 2713} {Pfam: wnt family [PF00110.21, score=158.2]} {Human: ENSG00000115596, WNT6, Wnt family member 6, [Score=77.4, Expect=1e-14]; ENSG00000134245, WNT2B, Wnt family member 2B, [Score=74.3, Expect=1e-13]} {Mouse: ENSMUSG00000033227, Wnt6, wingless-type MMTV integration site family, member 6, [Score=74.3, Expect=7e-14]; ENSMUSG00000027840, Wnt2b, wingless-type MMTV integration site family, member 2B, [Score=73.9, Expect=1e-13]} {Dmel: FBgn0031902, Wnt6, Wnt oncogene analog 6, [Score=70.9, Expect=9e-13]} {Celegans: WBGene00000857, cwn-1, [Score=73.6, Expect=6e-14]} {Smed: dd_Smed_v6_13487_0_1, dd_Smed_v6_13487_0_1, [Score=70.9, Expect=3e-13]} {RNA1509_23528} {RNA1310_12823.1, RNA1509_23528} {RNA1509_23528, RNA815_8552}
57. MligTC455_29874 65 1.36 Mlig455_037947, Mlig455_068699

Neo: -

Age: logFC(26M/2M)=-0.467

ANKRD50 1.907 - - - - 0.960 0.947

Mlig455_037947 {REF} {Length: 4099} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=309.9]; Ankyrin repeat [PF00023.32, score=295.0]; Ankyrin repeat [PF13606.8, score=230.6]; Ankyrin repeats (many copies) [PF13637.8, score=228.6]; Ankyrin repeats (many copies) [PF13857.8, score=200.7]; Glutamine amidotransferase domain [PF13537.8, score=68.9]; PEGA domain [PF08308.13, score=35.0]; Mab-21 protein [PF03281.16, score=29.5]; Nucleoplasmin/nucleophosmin domain [PF03066.17, score=26.4]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=276, Expect=2e-75]; ENSG00000029534, ANK1, ankyrin 1, [Score=270, Expect=5e-73]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=274, Expect=8e-75]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=256, Expect=7e-69]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=258, Expect=1e-69]} {Smed: dd_Smed_v6_2072_0_29, dd_Smed_v6_2072_0_29, [Score=256, Expect=2e-71]} {RNA1509_26004, RNA1509_28959} {RNA1310_3906.1, RNA1509_28959} {RNA1509_28959, RNA815_1664.1}

Mlig455_068699 {REF} {Length: 2234} {Pfam: Mab-21 protein [PF03281.16, score=31.1]} {RNA1509_26004} {RNA1310_3906.1} {RNA815_1664.1}
58. MligTC455_13030 30 0.63 Mlig455_030520

Neo: -

Age: -

1.901 - - - - 0.986 0.915 Mlig455_030520 {REF} {Length: 3950} {RNA1509_41925} {RNA1310_32300.1, RNA1509_41925} {RNA1509_41925, RNA815_29217}
59. MligTC455_27186 28 0.57 Mlig455_010236

Neo: -

Age: logFC(26M/2M)=-1.855

1.901 1.000 - - - 0.901 - Mlig455_010236 {REF} {Length: 486} {RNA1509_7146} {RNA1310_76234.2} {RNA815_34947.2}
60. MligTC455_53415 319 6.64 Mlig455_053444

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.862

Region-enriched R2: 4.179/0.00011

RP1 1.901 - - - - 0.938 0.963 Mlig455_053444 {REF} {Length: 4944} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.3]; Doublecortin [PF03607.19, score=100.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.5]; Fibroblast growth factor [PF00167.20, score=18.6]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=471, Expect=6e-145]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=453, Expect=3e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.9, Expect=1e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=691, Expect=0.0]} {RNA1509_59703} {RNA1310_2710} {RNA815_17469}
61. MligTC455_44120 125 2.61 Mlig455_041513

Neo: -

Age: Up-Down-Down

Region-enriched R2: 7.169/0.00020

1.9 - - - - 0.940 0.960 Mlig455_041513 {REF} {Length: 644} {NoTransDecoderORF} {RNA1310_39164} {RNA815_4344}
62. MligTC455_53414 331 6.9 Mlig455_053442

Neo: -

Age: -

Region-specific R2: 4.308

Region-enriched R2: 3.374/0.00040

RP1 1.899 - - - - 0.938 0.961 Mlig455_053442 {REF} {Length: 1156} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.8]; Doublecortin [PF03607.19, score=103.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.0]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=473, Expect=5e-146]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=454, Expect=1e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.5, Expect=2e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=698, Expect=0.0]} {RNA1509_21828} {RNA1310_33070.1} {RNA815_13802.1}
63. MligTC455_12991 30 0.62 Mlig455_037487

Neo: -

Age: -

CHRNA6 1.896 - - - - 0.952 0.944 Mlig455_037487 {REF} {Length: 1592} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=70.8]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=55.6]} {Human: ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=119, Expect=5e-29]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=110, Expect=4e-26]; ENSMUSG00000027577, Chrna4, cholinergic receptor, nicotinic, alpha polypeptide 4, [Score=109, Expect=3e-25]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=107, Expect=5e-25]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=107, Expect=8e-25]; ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=106, Expect=2e-24]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=111, Expect=4e-26]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=111, Expect=1e-26]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=112, Expect=5e-27]} {RNA1310_100091} {RNA815_18433}
64. MligTC455_43676 56 1.16 Mlig455_058053, Mlig455_058096

Neo: -

Age: -

1.896 1.000 - - - 0.896 -

Mlig455_058053 {REF} {Length: 391} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_102705} {RNA815_52459}

Mlig455_058096 {REF} {Length: 1983} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=51.3]} {Smed: dd_Smed_v6_9783_0_1, dd_Smed_v6_9783_0_1, [Score=90.1, Expect=1e-19]} {RNA1509_1472} {RNA1310_25467} {RNA815_39314}
65. MligTC455_44712 665 13.86 Mlig455_017186

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.471

Region-specific R2: 4.141

Region-enriched R2: 3.536/0.00000

1.896 - - - - 0.945 0.951 Mlig455_017186 {REF} {Length: 1018} {RNA1509_34252} {RNA1310_54269.1} {RNA815_55074}
66. MligTC455_45580 42 0.88 Mlig455_010918

Neo: -

Age: Down-Down-Down

1.893 - - - - 0.933 0.960 Mlig455_010918 {REF} {Length: 2621} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=86.4]; Anti-sigma-K factor rskA [PF10099.11, score=25.8]} {Smed: dd_Smed_v6_16346_0_1, dd_Smed_v6_16346_0_1, [Score=78.6, Expect=5e-15]} {RNA1310_36429} {RNA815_37174}
67. MligTC455_19876 135 2.82 Mlig455_024520, Mlig455_024523

Neo: -

Age: -

1.893 - - - - 0.955 0.938

Mlig455_024520 {REF} {Length: 2352} {Pfam: CD20-like family [PF04103.17, score=40.9]} {Mouse: ENSMUSG00000048004, Tmem196, transmembrane protein 196, [Score=63.5, Expect=2e-12]} {Smed: dd_Smed_v6_14043_0_1, dd_Smed_v6_14043_0_1, [Score=184, Expect=5e-59]} {RNA1509_25506} {RNA1310_9338} {RNA815_23744}

Mlig455_024523 {REF} {Length: 2311} {Smed: dd_Smed_v6_14043_0_1, dd_Smed_v6_14043_0_1, [Score=153, Expect=3e-47]} {RNA1509_25506} {RNA1310_9338} {RNA815_23744}
68. MligTC455_35000 20 0.42 Mlig455_050562

Neo: -

Age: -

KCNC1 1.892 0.961 - - - 0.931 - Mlig455_050562 {REF} {Length: 3042} {Pfam: Ion transport protein [PF00520.33, score=116.8]; BTB/POZ domain [PF02214.24, score=75.0]; Ion channel [PF07885.18, score=42.0]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=211, Expect=2e-60]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=209, Expect=1e-58]; ENSG00000182674, KCNB2, potassium voltage-gated channel subfamily B member 2, [Score=206, Expect=3e-56]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=204, Expect=3e-57]; ENSG00000158445, KCNB1, potassium voltage-gated channel subfamily B member 1, [Score=204, Expect=1e-55]; ENSG00000131398, KCNC3, potassium voltage-gated channel subfamily C member 3, [Score=203, Expect=7e-56]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=212, Expect=3e-60]; ENSMUSG00000050556, Kcnb1, potassium voltage gated channel, Shab-related subfamily, member 1, [Score=209, Expect=2e-57]; ENSMUSG00000092083, Kcnb2, potassium voltage gated channel, Shab-related subfamily, member 2, [Score=206, Expect=2e-56]; ENSMUSG00000027895, Kcnc4, potassium voltage gated channel, Shaw-related subfamily, member 4, [Score=204, Expect=4e-57]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=203, Expect=1e-56]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [Score=203, Expect=4e-56]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=223, Expect=2e-65]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=224, Expect=8e-65]} {Smed: dd_Smed_v6_20858_0_1, dd_Smed_v6_20858_0_1, [RH, Score=567, Expect=0.0]} {RNA1509_22940} {RNA1310_28483} {RNA815_31040}
69. MligTC455_46924 1562 32.53 Mlig455_042561

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.240

Region-enriched R2: 5.226/0.00021
Region-enriched R3: 3.273/0.00853

PI16 1.891 - - - - 0.938 0.953 Mlig455_042561 {REF} {Length: 1929} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=59.8]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=75.5, Expect=4e-14]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [Score=78.6, Expect=3e-15]; ENSMUSG00000020213, Glipr1l1, GLI pathogenesis-related 1 like 1, [Score=75.1, Expect=5e-15]} {Dmel: FBgn0038126, CG8483, [Score=65.9, Expect=2e-11]} {Celegans: WBGene00003055, lon-1, LONg, [Score=65.9, Expect=7e-12]} {Smed: dd_Smed_v6_2021_0_1, dd_Smed_v6_2021_0_1, [RH, Score=140, Expect=2e-36]} {RNA1509_33691, RNA1509_4403} {RNA1310_19427.1, RNA1509_33691, RNA1509_4403} {RNA1509_33691, RNA1509_4403, RNA815_7689.1}
70. MligTC455_35739 91 1.9 Mlig455_050779

Neo: -

Age: Up-Down-Down

ADGRL2 1.89 - - - - 0.983 0.907 Mlig455_050779 {REF} {Length: 4277} {Pfam: 7 transmembrane receptor (Secretin family) [PF00002.26, score=110.1]; Pentaxin family [PF00354.19, score=43.4]; Hormone receptor domain [PF02793.24, score=35.9]; Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=33.0]; GPCR-Autoproteolysis INducing (GAIN) domain [PF16489.7, score=20.5]; Myc amino-terminal region [PF01056.20, score=18.8]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [RH, Score=140, Expect=5e-33]; ENSG00000072071, ADGRL1, adhesion G protein-coupled receptor L1, [RH, Score=139, Expect=2e-32]; ENSG00000150471, ADGRL3, adhesion G protein-coupled receptor L3, [RH, Score=133, Expect=9e-31]} {Mouse: ENSMUSG00000028184, Adgrl2, adhesion G protein-coupled receptor L2, [RH, Score=142, Expect=1e-33]; ENSMUSG00000013033, Adgrl1, adhesion G protein-coupled receptor L1, [RH, Score=140, Expect=6e-33]} {Celegans: WBGene00002252, lat-2, Latrophilin-like protein LAT-2, [RH, Score=124, Expect=2e-28]} {Smed: dd_Smed_v6_16446_0_2, dd_Smed_v6_16446_0_2, [RH, Score=444, Expect=1e-139]} {RNA1509_25495} {RNA1310_3070} {RNA815_2153}
71. MligTC455_27216 56 1.18 Mlig455_022418

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.523

TRPM3 1.888 - - - - 0.950 0.938 Mlig455_022418 {REF} {Length: 4794} {Pfam: SLOG in TRPM [PF18139.3, score=136.8]; Ion transport protein [PF00520.33, score=41.0]; SLOG in TRPM, prokaryote [PF18171.3, score=34.2]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=317, Expect=2e-88]; ENSG00000119121, TRPM6, transient receptor potential cation channel subfamily M member 6, [Score=316, Expect=4e-88]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=319, Expect=4e-90]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=309, Expect=7e-88]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=255, Expect=4e-69]} {Smed: dd_Smed_v6_9288_0_1, dd_Smed_v6_9288_0_1, [Score=418, Expect=3e-126]} {RNA1509_17593} {RNA1310_1651, RNA1509_17593} {RNA1509_17593, RNA815_2281}
72. MligTC455_29915 50 1.04 Mlig455_027934

Neo: -

Age: Down-Up-Up

Region-enriched R2: 6.881/0.04464

ANGPTL1 1.888 - - - - 0.924 0.964 Mlig455_027934 {REF} {Length: 2265} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=43.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=48.9, Expect=9e-06]} {Dmel: FBgn0031804, CG9500, [Score=53.1, Expect=9e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=49.7, Expect=1e-06]} {RNA1509_53291} {RNA1310_38229.1} {RNA815_10579.1}
73. MligTC455_44922 15 0.31 Mlig455_040611

Neo: -

Age: -

AC254952.1 1.887 0.966 - - - 0.921 - Mlig455_040611 {REF} {Length: 1658} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=86.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=85.3]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=1e-40]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=2e-40]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=2e-40]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=147, Expect=9e-39]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=129, Expect=1e-32]} {Celegans: WBGene00001133, eat-2, Neuronal acetylcholine receptor subunit eat-2, [Score=136, Expect=2e-35]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=136, Expect=2e-35]} {RNA1310_45581} {RNA815_21574}
74. MligTC455_31462 23 0.48 Mlig455_000844

Neo: -

Age: -

1.886 0.928 - - - 0.958 - Mlig455_000844 {REF} {Length: 2564} {Pfam: Methyltransferase FkbM domain [PF05050.14, score=39.1]} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=81.6, Expect=5e-18]} {RNA1509_6604} {RNA1310_43619} {RNA815_6128.2}
75. MligTC455_45021 381 7.95 Mlig455_046686

Neo: -

Age: Down-Up-Up

Region-enriched R2: 3.428/0.03156

AVP 1.886 - - - - 0.919 0.967 Mlig455_046686 {REF} {Length: 1388} {Pfam: Neurohypophysial hormones, C-terminal Domain [PF00184.19, score=36.2]} {Human: ENSG00000101200, AVP, arginine vasopressin, [Score=54.3, Expect=2e-09]} {Mouse: ENSMUSG00000037727, Avp, arginine vasopressin, [Score=53.1, Expect=3e-09]} {RNA1509_50574} {RNA1310_38922} {RNA815_23813}
76. MligTC455_22212 1732 36.09 Mlig455_009239, Mlig455_009645, Mlig455_037058

Neo: -

Age: logFC(26M/2M)=-0.722

Region-specific R2: 6.329

Region-enriched R2: 6.728/0.00000

LMNA 1.885 0.915 - - - 0.970 -

Mlig455_009239 {REF} {Length: 2842} {Pfam: Intermediate filament protein [PF00038.23, score=176.1]; Lamin Tail Domain [PF00932.21, score=51.0]; Myosin tail [PF01576.21, score=18.0]} {Human: ENSG00000160789, LMNA, lamin A/C, [Score=176, Expect=8e-47]} {Mouse: ENSMUSG00000028063, Lmna, lamin A, [Score=172, Expect=1e-45]} {Dmel: FBgn0002525, Lam, Lamin, [Score=189, Expect=9e-52]} {Celegans: WBGene00002050, ifa-1, Intermediate filament protein ifa-1, [RH, Score=404, Expect=6e-134]} {Smed: dd_Smed_v6_3871_0_1, dd_Smed_v6_3871_0_1, [RH, Score=563, Expect=0.0]} {RNA1509_18286} {RNA1310_9741.1} {RNA815_3167}

Mlig455_009645 {REF} {Length: 2337} {Pfam: Intermediate filament protein [PF00038.23, score=176.1]; Lamin Tail Domain [PF00932.21, score=51.0]; Myosin tail [PF01576.21, score=18.0]} {Human: ENSG00000160789, LMNA, lamin A/C, [Score=176, Expect=8e-47]} {Mouse: ENSMUSG00000028063, Lmna, lamin A, [Score=172, Expect=1e-45]} {Dmel: FBgn0002525, Lam, Lamin, [Score=189, Expect=9e-52]} {Celegans: WBGene00002050, ifa-1, Intermediate filament protein ifa-1, [RH, Score=404, Expect=6e-134]} {Smed: dd_Smed_v6_3871_0_1, dd_Smed_v6_3871_0_1, [RH, Score=563, Expect=0.0]} {RNA1509_18286} {RNA1310_9741.1} {RNA815_3167}

Mlig455_037058 {REF} {Length: 4944} {Pfam: Intermediate filament protein [PF00038.23, score=176.1]; Lamin Tail Domain [PF00932.21, score=51.0]; Myosin tail [PF01576.21, score=18.0]} {Human: ENSG00000160789, LMNA, lamin A/C, [Score=176, Expect=8e-47]} {Mouse: ENSMUSG00000028063, Lmna, lamin A, [Score=172, Expect=1e-45]} {Dmel: FBgn0002525, Lam, Lamin, [Score=189, Expect=9e-52]} {Celegans: WBGene00002050, ifa-1, Intermediate filament protein ifa-1, [RH, Score=404, Expect=6e-134]} {Smed: dd_Smed_v6_3871_0_1, dd_Smed_v6_3871_0_1, [RH, Score=563, Expect=0.0]} {RNA1509_18286, RNA1509_31019, RNA1509_37437} {RNA1310_9741.1, RNA1509_18286, RNA1509_31019, RNA1509_37437} {RNA1509_18286, RNA1509_31019, RNA1509_37437, RNA815_3167}
77. MligTC455_25072 4443 92.56 Mlig455_015899

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.175

Region-enriched R2: 4.389/0.00000

PI16 1.885 - - - - 0.927 0.958 Mlig455_015899 {REF} {Length: 2017} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=71.8]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=112, Expect=1e-26]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [RH, Score=115, Expect=5e-28]} {Dmel: FBgn0038126, CG8483, [Score=95.5, Expect=2e-21]} {Celegans: WBGene00011462, vap-2, Venom-Allergen-like Protein, [RH, Score=85.5, Expect=5e-18]} {Smed: dd_Smed_v6_2512_0_1, dd_Smed_v6_2512_0_1, [Score=140, Expect=2e-39]} {RNA1509_5027} {RNA1310_1356.1} {RNA815_4508}
78. MligTC455_45861 18 0.38 Mlig455_034439

Neo: -

Age: -

1.883 - - - - 0.954 0.929 Mlig455_034439 {REF} {Length: 1135} {RNA1310_86023}
79. MligTC455_14310 27 0.56 Mlig455_021495

Neo: -

Age: -

Regeneration-upregulated R2: 3.309

Regeneration-enriched R2: 3.309

1.881 - - - - 0.986 0.895 Mlig455_021495 {REF} {Length: 4005} {RNA1509_54101} {RNA1310_16857} {RNA815_29628}
80. MligTC455_13166 186 3.88 Mlig455_018849

Neo: -

Age: -

Region-specific R2: 6.227

1.88 0.911 - - - 0.969 - Mlig455_018849 {REF} {Length: 693} {Pfam: FAD dependent oxidoreductase [PF01266.26, score=209.8]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=21.6]; FAD binding domain [PF01494.21, score=20.4]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=19.9]; FAD binding domain [PF00890.26, score=18.9]} {Mouse: ENSMUSG00000033624, Pdpr, pyruvate dehydrogenase phosphatase regulatory subunit, [Score=51.6, Expect=2e-06]} {Smed: dd_Smed_v6_5776_0_1, dd_Smed_v6_5776_0_1, [RH, Score=246, Expect=2e-77]} {RNA1509_49819} {RNA1310_28647} {RNA815_1682.1}
81. MligTC455_41226 44 0.92 Mlig455_019357, Mlig455_059122

Neo: -

Age: -

GALNT1 1.88 - - - - 0.911 0.969

Mlig455_019357 {REF} {Length: 1606} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=97.5]; Glycosyltransferase like family 2 [PF13641.8, score=38.9]; N-terminal domain of galactosyltransferase [PF02709.16, score=29.1]; Glycosyltransferase like family 2 [PF10111.11, score=18.5]} {Human: ENSG00000141429, GALNT1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=318, Expect=2e-103]; ENSG00000139629, GALNT6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=311, Expect=4e-100]; ENSG00000257594, GALNT4, polypeptide N-acetylgalactosaminyltransferase 4, [Score=305, Expect=3e-98]; ENSG00000259075, POC1B-GALNT4, POC1B-GALNT4 readthrough, [Score=305, Expect=3e-98]} {Mouse: ENSMUSG00000000420, Galnt1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=316, Expect=1e-102]; ENSMUSG00000037280, Galnt6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=308, Expect=9e-99]; ENSMUSG00000060988, Galnt13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=302, Expect=3e-97]} {Dmel: FBgn0050463, CG30463, [Score=345, Expect=5e-113]} {Celegans: WBGene00001630, gly-5, Polypeptide N-acetylgalactosaminyltransferase 5, [Score=350, Expect=3e-115]} {Smed: dd_Smed_v6_8580_0_1, dd_Smed_v6_8580_0_1, [Score=353, Expect=1e-117]} {RNA1310_25598} {RNA815_36943}

Mlig455_059122 {REF} {Length: 2150} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=96.4]; Glycosyltransferase like family 2 [PF13641.8, score=35.9]; N-terminal domain of galactosyltransferase [PF02709.16, score=29.5]} {Human: ENSG00000141429, GALNT1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=313, Expect=2e-101]; ENSG00000139629, GALNT6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=307, Expect=2e-98]; ENSG00000257594, GALNT4, polypeptide N-acetylgalactosaminyltransferase 4, [Score=300, Expect=6e-96]; ENSG00000259075, POC1B-GALNT4, POC1B-GALNT4 readthrough, [Score=299, Expect=7e-96]; ENSG00000144278, GALNT13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=298, Expect=1e-95]} {Mouse: ENSMUSG00000000420, Galnt1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=311, Expect=1e-100]; ENSMUSG00000037280, Galnt6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=305, Expect=1e-97]; ENSMUSG00000060988, Galnt13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=298, Expect=8e-96]; ENSMUSG00000026994, Galnt3, polypeptide N-acetylgalactosaminyltransferase 3, [Score=296, Expect=5e-94]; ENSMUSG00000026828, Galnt5, polypeptide N-acetylgalactosaminyltransferase 5, [Score=296, Expect=2e-91]} {Dmel: FBgn0050463, CG30463, [Score=340, Expect=3e-111]} {Celegans: WBGene00001630, gly-5, Polypeptide N-acetylgalactosaminyltransferase 5, [Score=344, Expect=3e-113]} {Smed: dd_Smed_v6_8580_0_1, dd_Smed_v6_8580_0_1, [Score=350, Expect=3e-116]} {RNA1310_25598} {RNA815_36943}
82. MligTC455_15836 36 0.74 Mlig455_000292

Neo: -

Age: Up-Down-Down

PLEKHG5 1.879 - - - - 0.962 0.917 Mlig455_000292 {REF} {Length: 4512} {Pfam: RhoGEF domain [PF00621.22, score=89.5]; PH domain [PF17838.3, score=20.5]; Pleckstrin homology domain [PF15405.8, score=19.2]} {Human: ENSG00000171680, PLEKHG5, pleckstrin homology and RhoGEF domain containing G5, [Score=197, Expect=6e-52]} {Mouse: ENSMUSG00000039713, Plekhg5, pleckstrin homology domain containing, family G (with RhoGef domain) member 5, [Score=199, Expect=5e-53]} {Dmel: FBgn0261556, CG42674, [Score=147, Expect=6e-36]} {Celegans: WBGene00006476, rhgf-2, RHGF-2; RHo Guanine nucleotide exchange Factor, [RH, Score=147, Expect=3e-36]} {Smed: dd_Smed_v6_10072_0_1, dd_Smed_v6_10072_0_1, [RH, Score=179, Expect=8e-48]} {RNA1310_47096} {RNA815_53026}
83. MligTC455_26322 65 1.35 Mlig455_042546

Neo: -

Age: -

GRID2 1.879 - - - - 0.920 0.959 Mlig455_042546 {REF} {Length: 3217} {Pfam: Ligand-gated ion channel [PF00060.28, score=79.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=49.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=35.5]; Receptor family ligand binding region [PF01094.30, score=33.7]} {Human: ENSG00000152208, GRID2, glutamate ionotropic receptor delta type subunit 2, [Score=127, Expect=3e-29]} {Mouse: ENSMUSG00000071424, Grid2, glutamate receptor, ionotropic, delta 2, [Score=129, Expect=5e-30]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=133, Expect=1e-31]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=105, Expect=6e-23]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=238, Expect=8e-71]} {RNA1310_27694} {RNA815_34664}
84. MligTC455_31104 22 0.46 Mlig455_040032, Mlig455_070983

Neo: -

Age: -

SYT17 1.879 - - - - 0.900 0.979

Mlig455_040032 {REF} {Length: 2712} {Pfam: C2 domain [PF00168.32, score=79.2]} {Human: ENSG00000103528, SYT17, synaptotagmin 17, [Score=127, Expect=1e-30]} {Mouse: ENSMUSG00000058420, Syt17, synaptotagmin XVII, [Score=126, Expect=1e-30]} {Dmel: FBgn0028400, Syt4, Synaptotagmin 4, [Score=88.6, Expect=2e-18]} {Celegans: WBGene00004922, snt-2, Synaptotagmin 2, [Score=94.0, Expect=1e-20]} {Smed: dd_Smed_v6_19213_0_1, dd_Smed_v6_19213_0_1, [Score=96.7, Expect=3e-21]} {RNA1310_17303}

Mlig455_070983 {REF} {Length: 1947} {Pfam: C2 domain [PF00168.32, score=79.2]} {Human: ENSG00000103528, SYT17, synaptotagmin 17, [Score=127, Expect=1e-30]} {Mouse: ENSMUSG00000058420, Syt17, synaptotagmin XVII, [Score=126, Expect=1e-30]} {Dmel: FBgn0028400, Syt4, Synaptotagmin 4, [Score=88.6, Expect=2e-18]} {Celegans: WBGene00004922, snt-2, Synaptotagmin 2, [Score=94.0, Expect=1e-20]} {Smed: dd_Smed_v6_19213_0_1, dd_Smed_v6_19213_0_1, [Score=96.7, Expect=3e-21]} {RNA1310_17303}
85. MligTC455_49862 26 0.54 Mlig455_019435

Neo: -

Age: -

SHOX2 1.878 - - - - 0.971 0.907 Mlig455_019435 {REF} {Length: 904} {Pfam: Homeodomain [PF00046.31, score=84.8]; Homeobox KN domain [PF05920.13, score=23.6]} {Human: ENSG00000168779, SHOX2, short stature homeobox 2, [Score=89.0, Expect=4e-22]; ENSG00000185960, SHOX, short stature homeobox, [Score=87.0, Expect=5e-21]} {Mouse: ENSMUSG00000027833, Shox2, short stature homeobox 2, [Score=89.0, Expect=3e-22]} {Dmel: FBgn0085396, CG34367, [Score=89.7, Expect=9e-22]} {Celegans: WBGene00006744, unc-4, Homeobox protein unc-4, [Score=83.6, Expect=5e-20]} {Smed: dd_Smed_v6_22163_0_1, dd_Smed_v6_22163_0_1, [Score=86.3, Expect=2e-20]} {RNA1310_51707} {RNA815_41055}
86. MligTC455_43454 36 0.74 Mlig455_043999

Neo: -

Age: -

1.876 - - - - 0.980 0.896 Mlig455_043999 {REF} {Length: 2456} {Dmel: FBgn0259222, CG42322, [RH, Score=101, Expect=3e-22]} {Smed: dd_Smed_v6_18554_0_1, dd_Smed_v6_18554_0_1, [Score=82.4, Expect=1e-17]} {RNA1310_20749} {RNA815_38231}
87. MligTC455_26411 55 1.14 Mlig455_024911

Neo: -

Age: -

1.874 0.961 - - - 0.913 - Mlig455_024911 {REF} {Length: 2411} {Pfam: SH3 domain [PF00018.30, score=28.9]; Variant SH3 domain [PF14604.8, score=22.2]; Variant SH3 domain [PF07653.19, score=22.1]} {Smed: dd_Smed_v6_8729_0_1, dd_Smed_v6_8729_0_1, [RH, Score=60.1, Expect=5e-10]} {RNA1310_32104} {RNA815_32970}
88. MligTC455_52935 29 0.61 Mlig455_014479

Neo: -

Age: -

PROX1 1.874 0.909 - - - 0.965 - Mlig455_014479 {REF} {Length: 1320} {Pfam: Homeo-prospero domain [PF05044.14, score=192.8]} {Human: ENSG00000117707, PROX1, prospero homeobox 1, [Score=163, Expect=5e-44]; ENSG00000119608, PROX2, prospero homeobox 2, [Score=159, Expect=4e-43]} {Mouse: ENSMUSG00000010175, Prox1, prospero homeobox 1, [Score=163, Expect=4e-44]; ENSMUSG00000042320, Prox2, prospero homeobox 2, [Score=162, Expect=2e-44]} {Dmel: FBgn0004595, pros, prospero, [Score=182, Expect=1e-50]} {Celegans: WBGene00000448, pros-1, Homeobox protein prospero homolog 1, [Score=178, Expect=1e-50]} {Smed: dd_Smed_v6_48508_0_1, dd_Smed_v6_48508_0_1, [Score=165, Expect=9e-50]} {RNA1310_102283}
89. MligTC455_44904 1501 31.27 Mlig455_021814

Neo: -

Age: Down-Up-Up

Region-specific R2: 3.865

Region-enriched R2: 3.792/0.00000

1.872 - - - - 0.978 0.894 Mlig455_021814 {REF} {Length: 959} {RNA1509_15805} {RNA1310_67099.1, RNA1509_15805} {RNA1509_15805, RNA815_17533}
90. MligTC455_54204 344 7.17 Mlig455_006398

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.351

Region-specific R2: 5.395

Region-enriched R2: 4.187/0.01201

MYH6 1.872 - - - - 0.903 0.969 Mlig455_006398 {REF} {Length: 7465} {Pfam: Myosin head (motor domain) [PF00063.23, score=927.6]; Myosin tail [PF01576.21, score=593.3]; Myosin N-terminal SH3-like domain [PF02736.21, score=60.7]; Crescentin protein [PF19220.2, score=26.4]; Macoilin family [PF09726.11, score=19.0]} {Human: ENSG00000197616, MYH6, myosin heavy chain 6, [RH, Score=2074, Expect=0.0]; ENSG00000092054, MYH7, myosin heavy chain 7, [RH, Score=2064, Expect=0.0]; ENSG00000125414, MYH2, myosin heavy chain 2, [RH, Score=2019, Expect=0.0]; ENSG00000109061, MYH1, myosin heavy chain 1, [RH, Score=2012, Expect=0.0]; ENSG00000133020, MYH8, myosin heavy chain 8, [RH, Score=2006, Expect=0.0]; ENSG00000264424, MYH4, myosin heavy chain 4, [RH, Score=1991, Expect=0.0]; ENSG00000109063, MYH3, myosin heavy chain 3, [RH, Score=1973, Expect=0.0]} {Mouse: ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [RH, Score=2073, Expect=0.0]; ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [RH, Score=2063, Expect=0.0]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [RH, Score=2039, Expect=0.0]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [RH, Score=2016, Expect=0.0]; ENSMUSG00000055775, Myh8, myosin, heavy polypeptide 8, skeletal muscle, perinatal, [RH, Score=2014, Expect=0.0]; ENSMUSG00000033196, Myh2, myosin, heavy polypeptide 2, skeletal muscle, adult, [RH, Score=2008, Expect=0.0]; ENSMUSG00000020908, Myh3, myosin, heavy polypeptide 3, skeletal muscle, embryonic, [RH, Score=1981, Expect=0.0]; ENSMUSG00000060180, Myh13, myosin, heavy polypeptide 13, skeletal muscle, [RH, Score=1978, Expect=0.0]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [RH, Score=2100, Expect=0.0]} {Celegans: WBGene00019064, myo-5, MYOsin heavy chain structural genes, [RH, Score=1993, Expect=0.0]} {Smed: dd_Smed_v6_579_0_1, dd_Smed_v6_579_0_1, [RH, Score=2702, Expect=0.0]} {RNA1509_16048, RNA1509_42411} {RNA1310_1388, RNA1509_42411} {RNA1509_42411, RNA815_129.1}
91. MligTC455_18333 273 5.7 Mlig455_010935

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.059/0.00307

1.87 - - - - 0.914 0.956 Mlig455_010935 {REF} {Length: 510} {RNA1310_33328.2} {RNA815_15093.1}
92. MligTC455_40714 93 1.94 Mlig455_008848

Neo: -

Age: -

Region-enriched R2: 5.100/0.02617

1.869 - - - - 0.918 0.951 Mlig455_008848 {REF} {Length: 2258} {RNA1310_21537} {RNA815_13165}
93. MligTC455_15883 95 1.98 Mlig455_020080, Mlig455_040893

Neo: -

Age: -

1.868 - - - - 0.997 0.871

Mlig455_020080 {REF} {Length: 1487} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=20.9]} {RNA1310_27849} {RNA815_37376}

Mlig455_040893 {REF} {Length: 1486} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=21.0]} {RNA1310_27849} {RNA815_37376}
94. MligTC455_41448 192 4.01 Mlig455_066626

Neo: -

Age: -

Region-specific R2: 6.449

Region-enriched R2: 4.988/0.02499

1.868 0.913 - - - 0.955 - Mlig455_066626 {REF} {Length: 987} {Pfam: F5/8 type C domain [PF00754.27, score=25.0]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [Score=52.4, Expect=8e-09]} {RNA1509_36923} {RNA1310_37535} {RNA815_20943}
95. MligTC455_46581 31 0.64 Mlig455_042524

Neo: -

Age: -

1.868 1.000 - - - 0.868 - Mlig455_042524 {REF} {Length: 975} {RNA1509_46101} {RNA1310_32444} {RNA815_42659}
96. MligTC455_49824 466 9.71 Mlig455_036536

Neo: -

Age: -

Region-specific R2: 4.841

Region-enriched R2: 3.862/0.00010

1.868 - - - - 0.893 0.975 Mlig455_036536 {REF} {Length: 1139} {Pfam: Nucleoporin FG repeat region [PF13634.8, score=21.2]} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [RH, Score=49.3, Expect=7e-08]} {RNA1509_18714, RNA1509_59524} {RNA1310_41906, RNA1509_18714, RNA1509_59524} {RNA1509_18714, RNA1509_59524, RNA815_24488}
97. MligTC455_52223 30 0.62 Mlig455_029799

Neo: -

Age: -

GLRA2 1.868 - - - - 0.914 0.954 Mlig455_029799 {REF} {Length: 3197} {tRNA: Val(CAC),pseudo, score=27.6} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=152.8]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=122.6]} {Human: ENSG00000101958, GLRA2, glycine receptor alpha 2, [RH, Score=350, Expect=1e-116]; ENSG00000145451, GLRA3, glycine receptor alpha 3, [RH, Score=345, Expect=4e-115]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [RH, Score=338, Expect=3e-112]} {Mouse: ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [RH, Score=345, Expect=3e-115]; ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [RH, Score=342, Expect=2e-113]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [RH, Score=337, Expect=9e-112]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [RH, Score=334, Expect=1e-110]} {Dmel: FBgn0024963, GluClalpha, [RH, Score=301, Expect=8e-98]} {Celegans: WBGene00000232, avr-14, Inhibitory amino acid receptor subunit gbr-2A, [RH, Score=274, Expect=3e-88]} {Smed: dd_Smed_v6_24908_0_1, dd_Smed_v6_24908_0_1, [Score=265, Expect=1e-84]} {RNA1509_44790} {RNA1310_18585} {RNA815_38424}
98. MligTC455_15332 44 0.93 Mlig455_062622, Mlig455_067527

Neo: -

Age: -

Region-enriched R2: 7.516/0.00418

ASIC4 1.867 0.985 - - - 0.882 -

Mlig455_062622 {REF} {Length: 2228} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=73.0]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=47.4, Expect=7e-06]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=51.6, Expect=2e-07]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=55.8, Expect=3e-09]} {Smed: dd_Smed_v6_19727_0_1, dd_Smed_v6_19727_0_1, [Score=53.1, Expect=2e-08]} {RNA1310_17847} {RNA815_27317}

Mlig455_067527 {REF} {Length: 1916} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=147.3]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=50.1, Expect=1e-05]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=50.8, Expect=3e-06]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=54.7, Expect=1e-07]} {Smed: dd_Smed_v6_19727_0_1, dd_Smed_v6_19727_0_1, [Score=53.5, Expect=2e-07]} {RNA1310_17847} {RNA815_27317}
99. MligTC455_23101 397 8.28 Mlig455_048080

Neo: -

Age: -

Region-enriched R2: 3.122/0.00807

1.867 0.972 - - - 0.895 - Mlig455_048080 {REF} {Length: 721} {TRANSSPLICED} {RNA1509_16955} {RNA1310_49452, RNA1509_16955} {RNA1509_16955, RNA815_4585}
100. MligTC455_33552 905 18.86 Mlig455_014406, Mlig455_070160

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.705/0.03873

KCNH1 1.867 - - - - 0.916 0.951

Mlig455_014406 {REF} {Length: 5774} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=54.1]} {Human: ENSG00000143473, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=269, Expect=1e-82]; ENSG00000283965, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=269, Expect=1e-82]; ENSG00000140015, KCNH5, potassium voltage-gated channel subfamily H member 5, [Score=256, Expect=1e-74]} {Mouse: ENSMUSG00000058248, Kcnh1, potassium voltage-gated channel, subfamily H (eag-related), member 1, [Score=267, Expect=4e-79]; ENSMUSG00000034402, Kcnh5, potassium voltage-gated channel, subfamily H (eag-related), member 5, [Score=256, Expect=3e-75]} {Dmel: FBgn0000535, eag, ether a go-go, [Score=283, Expect=5e-84]} {Celegans: WBGene00001171, egl-2, EAG K+ channel EGL-2, [Score=240, Expect=1e-69]} {Smed: dd_Smed_v6_23063_0_1, dd_Smed_v6_23063_0_1, [Score=283, Expect=7e-86]} {RNA1509_16580} {RNA1310_9615} {RNA815_20522}

Mlig455_070160 {REF} {Length: 3641} {Pfam: Ion transport protein [PF00520.33, score=111.5]; Cyclic nucleotide-binding domain [PF00027.31, score=53.3]; Ion channel [PF07885.18, score=40.6]} {Human: ENSG00000143473, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=795, Expect=0.0]; ENSG00000283965, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=795, Expect=0.0]; ENSG00000140015, KCNH5, potassium voltage-gated channel subfamily H member 5, [Score=771, Expect=0.0]} {Mouse: ENSMUSG00000058248, Kcnh1, potassium voltage-gated channel, subfamily H (eag-related), member 1, [Score=794, Expect=0.0]; ENSMUSG00000034402, Kcnh5, potassium voltage-gated channel, subfamily H (eag-related), member 5, [Score=770, Expect=0.0]} {Dmel: FBgn0000535, eag, ether a go-go, [Score=838, Expect=0.0]} {Celegans: WBGene00001171, egl-2, EAG K+ channel EGL-2, [Score=688, Expect=0.0]} {Smed: dd_Smed_v6_18793_0_1, dd_Smed_v6_18793_0_1, [Score=895, Expect=0.0]} {RNA1509_16580} {RNA1310_6070} {RNA815_18231}

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