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Results for MligTC455_13409

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_13409 277 5.77 Mlig455_017067

Neo: -

Age: -

Region-enriched R4: 1.836/0.03370

PBLD Mlig455_017067 {REF} {Length: 1675} {TRANSSPLICED} {Pfam: Phenazine biosynthesis-like protein [PF02567.18, score=183.9]} {Human: ENSG00000108187, PBLD, phenazine biosynthesis like protein domain containing, [RH, Score=188, Expect=2e-57]} {Mouse: ENSMUSG00000112129, Pbld1, phenazine biosynthesis-like protein domain containing 1, [RH, Score=192, Expect=4e-59]} {Celegans: WBGene00011417, T04A11.2, [RH, Score=160, Expect=1e-46]} {RNA1509_44083} {RNA1310_21604} {RNA815_35633}

Cumulative graph for MligTC455_13409

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 2.106 3.166 0.25918 0.90723
RegionR2 -3.323 3.166 0.00006 0.00292
RegionR3 -0.253 3.166 0.65578 1.00000
RegionR4 1.836 3.166 0.00454 0.03370
RegionR5 0.834 3.166 0.06662 0.22999
RegionR6 -0.666 3.166 0.27067 0.85992
RegionR7 -0.432 3.166 0.63285 1.00000
RegionR8 -0.102 3.166 0.92677 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.314 3.166 0.12039 0.85024
RegenerationR2 2.089 3.166 0.00222 0.07103
RegenerationR3 0.634 3.166 0.27543 0.70953
RegenerationR4 -0.212 3.166 0.69525 0.95185
RegenerationR5 0.497 3.166 0.31685 0.74085
RegenerationR6 0.939 3.166 0.12224 0.43014
RegenerationBL 0.208 3.166 0.79499 1.00000
RegenerationTP 0.114 3.166 0.89972 1.00000


Genes with expression patterns similar to MligTC455_13409

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_13409 277 5.77 Mlig455_017067

Neo: -

Age: -

Region-enriched R4: 1.836/0.03370

PBLD 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_017067 {REF} {Length: 1675} {TRANSSPLICED} {Pfam: Phenazine biosynthesis-like protein [PF02567.18, score=183.9]} {Human: ENSG00000108187, PBLD, phenazine biosynthesis like protein domain containing, [RH, Score=188, Expect=2e-57]} {Mouse: ENSMUSG00000112129, Pbld1, phenazine biosynthesis-like protein domain containing 1, [RH, Score=192, Expect=4e-59]} {Celegans: WBGene00011417, T04A11.2, [RH, Score=160, Expect=1e-46]} {RNA1509_44083} {RNA1310_21604} {RNA815_35633}
2. MligTC455_12267 1146 23.88 Mlig455_020414

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.464

Region-enriched R4: 2.571/0.00351
Region-enriched R5: 1.608/0.04205

2.597 - - 0.776 0.966 - 0.855 Mlig455_020414 {REF} {Length: 1732} {Pfam: TATA element modulatory factor 1 DNA binding [PF12329.10, score=25.4]} {RNA1509_10012} {RNA1310_23404.1} {RNA815_8343.1}
3. MligTC455_35519 1708 35.59 Mlig455_014621

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.589

Region-enriched R4: 1.911/0.00012
Region-enriched R3: 1.380/0.00213
Region-enriched R5: 1.309/0.00075

SLC44A2 2.569 - - 0.773 0.955 - 0.841 Mlig455_014621 {REF} {Length: 3582} {Pfam: Plasma-membrane choline transporter [PF04515.14, score=313.8]} {Human: ENSG00000129353, SLC44A2, solute carrier family 44 member 2, [Score=436, Expect=1e-142]} {Mouse: ENSMUSG00000057193, Slc44a2, solute carrier family 44, member 2, [Score=451, Expect=7e-149]} {Dmel: FBgn0039637, Ctl2, Choline transporter-like 2, [Score=315, Expect=4e-96]} {Celegans: WBGene00018037, chtl-1, Choline transporter-like protein 1, [Score=373, Expect=1e-118]} {Smed: dd_Smed_v6_6488_0_1, dd_Smed_v6_6488_0_1, [Score=434, Expect=7e-142]} {RNA1509_14161, RNA1509_56009, RNA1509_8961} {RNA1310_8213, RNA1509_14161, RNA1509_56009, RNA1509_8961} {RNA1509_14161, RNA1509_56009, RNA1509_8961, RNA815_109}
4. MligTC455_23336 1585 33.01 Mlig455_007789

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.413

Region-enriched R3: 1.631/0.00000

2.437 - - 0.775 0.962 - 0.700 Mlig455_007789 {REF} {Length: 2108} {Pfam: PLAC8 family [PF04749.19, score=74.3]} {Smed: dd_Smed_v6_743_0_1, dd_Smed_v6_743_0_1, [RH, Score=114, Expect=3e-34]} {RNA1509_26743, RNA1509_28154, RNA1509_5161} {RNA1310_50991, RNA1509_26743, RNA1509_28154} {RNA1509_26743, RNA1509_28154, RNA815_15567.2}
5. MligTC455_46905 2015 41.97 Mlig455_053779

Neo: -

Age: logFC(26M/2M)=0.188

PDPR 2.436 - - - 0.719 0.960 0.757 Mlig455_053779 {REF} {Length: 3098} {Pfam: FAD dependent oxidoreductase [PF01266.26, score=144.0]; FAD dependent oxidoreductase central domain [PF16350.7, score=29.7]; Aminomethyltransferase folate-binding domain [PF01571.23, score=23.4]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=21.8]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=21.0]; FAD binding domain [PF00890.26, score=19.6]} {Human: ENSG00000090857, PDPR, pyruvate dehydrogenase phosphatase regulatory subunit, [Score=305, Expect=9e-91]} {Mouse: ENSMUSG00000033624, Pdpr, pyruvate dehydrogenase phosphatase regulatory subunit, [Score=279, Expect=2e-81]} {Dmel: FBgn0029706, CG3626, [Score=249, Expect=3e-70]} {Celegans: WBGene00013718, pdpr-1, Pyruvate Dehydrogenase Phosphatase Regulatory subunit, [Score=162, Expect=3e-41]} {Smed: dd_Smed_v6_4280_0_1, dd_Smed_v6_4280_0_1, [Score=206, Expect=1e-55]} {RNA1509_23369, RNA1509_6365} {RNA1310_5958.2, RNA1509_23369} {RNA1509_23369, RNA815_1712}
6. MligTC455_11112 617 12.86 Mlig455_008574

Neo: -

Age: logFC(26M/2M)=0.279

Region-enriched R4: 2.218/0.00591
Region-enriched R5: 1.831/0.00200

2.383 - 0.703 - 0.950 - 0.730 Mlig455_008574 {REF} {Length: 473} {NoTransDecoderORF} {RNA1509_284} {RNA1310_11148} {RNA815_6153}
7. MligTC455_17024 361 7.51 Mlig455_036730

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.762/0.04763

CTSO 1.819 - - - 0.981 - 0.838 Mlig455_036730 {REF} {Length: 2029} {TRANSSPLICED} {Pfam: Papain family cysteine protease [PF00112.25, score=166.5]; Peptidase C1-like family [PF03051.17, score=25.3]} {Human: ENSG00000263238, CTSO, cathepsin O, [RH, Score=169, Expect=1e-48]; ENSG00000256043, CTSO, cathepsin O, [RH, Score=169, Expect=1e-48]} {Mouse: ENSMUSG00000028015, Ctso, cathepsin O, [RH, Score=161, Expect=7e-46]} {Dmel: FBgn0260462, CG12163, [Score=130, Expect=3e-33]} {Celegans: WBGene00007055, tag-196, [Score=121, Expect=4e-30]} {Smed: dd_Smed_v6_456_0_1, dd_Smed_v6_456_0_1, [Score=124, Expect=2e-31]} {RNA1509_24611} {RNA1310_22386} {RNA815_10365}
8. MligTC455_47668 400 8.33 Mlig455_070881

Neo: -

Age: -

Regeneration-upregulated R4: 2.320

Regeneration-enriched R4: 2.320

SLC39A14 1.817 - - - 0.954 - 0.863 Mlig455_070881 {REF} {Length: 2614} {Pfam: ZIP Zinc transporter [PF02535.24, score=209.3]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=253, Expect=2e-78]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=248, Expect=6e-77]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=157, Expect=3e-42]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=216, Expect=2e-65]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=281, Expect=4e-90]} {RNA1509_23164} {RNA1310_12163.1} {RNA815_4574}
9. MligTC455_22881 768 16.01 Mlig455_002369, Mlig455_044567

Neo: -

Age: -

SLC4A8 1.787 - - - 0.957 - 0.830

Mlig455_002369 {REF} {Length: 5267} {Pfam: HCO3- transporter family [PF00955.23, score=715.2]; Band 3 cytoplasmic domain [PF07565.15, score=255.8]} {Human: ENSG00000050438, SLC4A8, solute carrier family 4 member 8, [Score=902, Expect=0.0]; ENSG00000144290, SLC4A10, solute carrier family 4 member 10, [Score=890, Expect=0.0]; ENSG00000033867, SLC4A7, solute carrier family 4 member 7, [Score=885, Expect=0.0]} {Mouse: ENSMUSG00000026904, Slc4a10, solute carrier family 4, sodium bicarbonate cotransporter-like, member 10, [RH, Score=896, Expect=0.0]} {Dmel: FBgn0259111, Ndae1, Na[+]-driven anion exchanger 1, [RH, Score=895, Expect=0.0]} {Celegans: WBGene00009920, abts-1, Anion exchange protein, [RH, Score=852, Expect=0.0]} {Smed: dd_Smed_v6_3003_0_2, dd_Smed_v6_3003_0_2, [RH, Score=1112, Expect=0.0]} {RNA1509_3113} {RNA1310_1565.3} {RNA815_527.1}

Mlig455_044567 {REF} {Length: 5338} {Pfam: HCO3- transporter family [PF00955.23, score=714.9]; Band 3 cytoplasmic domain [PF07565.15, score=255.8]} {Human: ENSG00000050438, SLC4A8, solute carrier family 4 member 8, [Score=902, Expect=0.0]; ENSG00000144290, SLC4A10, solute carrier family 4 member 10, [Score=889, Expect=0.0]; ENSG00000033867, SLC4A7, solute carrier family 4 member 7, [Score=885, Expect=0.0]} {Mouse: ENSMUSG00000026904, Slc4a10, solute carrier family 4, sodium bicarbonate cotransporter-like, member 10, [RH, Score=896, Expect=0.0]} {Dmel: FBgn0259111, Ndae1, Na[+]-driven anion exchanger 1, [RH, Score=898, Expect=0.0]} {Celegans: WBGene00009920, abts-1, Anion exchange protein, [RH, Score=852, Expect=0.0]} {Smed: dd_Smed_v6_3003_0_2, dd_Smed_v6_3003_0_2, [RH, Score=1111, Expect=0.0]} {RNA1509_3113, RNA1509_41661} {RNA1310_1565.3, RNA1509_3113, RNA1509_41661} {RNA1509_3113, RNA1509_41661, RNA815_527.1}
10. MligTC455_37298 680 14.17 Mlig455_052018, Mlig455_057237

Neo: -

Age: logFC(26M/2M)=-0.343

Region-enriched R3: 2.210/0.00000

1.784 - - - 0.954 - 0.830

Mlig455_052018 {REF} {Length: 2901} {Pfam: Innexin [PF00876.20, score=316.7]} {Dmel: FBgn0265274, Inx3, Innexin 3, [Score=93.2, Expect=1e-20]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=275, Expect=9e-89]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=267, Expect=7e-86]} {RNA1509_34561, RNA1509_39488, RNA1509_48225, RNA1509_59956} {RNA1310_23555, RNA1509_34561, RNA1509_39488, RNA1509_48225} {RNA1509_34561, RNA1509_39488, RNA1509_48225, RNA815_9532}

Mlig455_057237 {REF} {Length: 2860} {Pfam: Innexin [PF00876.20, score=316.7]} {Dmel: FBgn0265274, Inx3, Innexin 3, [Score=93.2, Expect=1e-20]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=275, Expect=9e-89]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=267, Expect=7e-86]} {RNA1509_28177, RNA1509_45524} {RNA1310_23555, RNA1509_28177, RNA1509_45524} {RNA1509_28177, RNA1509_45524, RNA815_9532}
11. MligTC455_44284 707 14.74 Mlig455_024219

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.444

Region-enriched R4: 6.318/0.00000
Region-enriched R5: 4.387/0.00005

RAB6B 1.77 - - 0.816 0.954 - - Mlig455_024219 {REF} {Length: 1131} {Pfam: Ras family [PF00071.24, score=83.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=51.5]; ADP-ribosylation factor family [PF00025.23, score=31.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=26.7]; RsgA GTPase [PF03193.18, score=25.1]; 50S ribosome-binding GTPase [PF01926.25, score=20.2]; Signal recognition particle receptor beta subunit [PF09439.12, score=19.4]} {Human: ENSG00000154917, RAB6B, RAB6B, member RAS oncogene family, [Score=73.6, Expect=2e-15]; ENSG00000175582, RAB6A, RAB6A, member RAS oncogene family, [Score=73.2, Expect=3e-15]; ENSG00000111540, RAB5B, RAB5B, member RAS oncogene family, [Score=70.5, Expect=3e-14]} {Mouse: ENSMUSG00000032549, Rab6b, RAB6B, member RAS oncogene family, [Score=73.6, Expect=1e-15]; ENSMUSG00000030704, Rab6a, RAB6A, member RAS oncogene family, [Score=73.2, Expect=2e-15]; ENSMUSG00000079657, Rab26, RAB26, member RAS oncogene family, [Score=72.4, Expect=9e-15]; ENSMUSG00000027935, Rab13, RAB13, member RAS oncogene family, [Score=71.2, Expect=1e-14]; ENSMUSG00000000711, Rab5b, RAB5B, member RAS oncogene family, [Score=70.5, Expect=2e-14]} {Dmel: FBgn0015797, Rab6, [Score=72.8, Expect=2e-15]} {Celegans: WBGene00004285, rab-37, RAB family, [Score=72.4, Expect=2e-15]} {Smed: dd_Smed_v6_2099_0_1, dd_Smed_v6_2099_0_1, [Score=73.2, Expect=1e-15]} {RNA1310_27566} {RNA815_20907}
12. MligTC455_51484 172 3.59 Mlig455_019492

Neo: Int S/G2/M

Age: -

Region-enriched R5: 3.072/0.02519

PXMP2 1.747 0.769 - - 0.978 - - Mlig455_019492 {REF} {Length: 2315} {TRANSSPLICED} {Pfam: Mpv17 / PMP22 family [PF04117.14, score=68.0]} {Human: ENSG00000176894, PXMP2, peroxisomal membrane protein 2, [RH, Score=105, Expect=7e-28]} {Mouse: ENSMUSG00000029499, Pxmp2, peroxisomal membrane protein 2, [RH, Score=115, Expect=6e-32]} {Dmel: FBgn0035252, CG7970, [RH, Score=84.7, Expect=8e-20]} {Smed: dd_Smed_v6_13953_0_1, dd_Smed_v6_13953_0_1, [Score=74.3, Expect=1e-16]} {RNA1509_31026, RNA1509_52775, RNA1509_55300} {RNA1310_31383.1, RNA1509_52775, RNA1509_55300} {RNA1509_52775, RNA1509_55300, RNA815_20167}
13. MligTC455_18887 333 6.93 Mlig455_045886

Neo: -

Age: -

Region-enriched R3: 2.872/0.03772

HRASLS 1.734 - - 0.776 0.958 - - Mlig455_045886 {REF} {Length: 1499} {Pfam: Lecithin retinol acyltransferase [PF04970.15, score=47.0]; PPPDE putative peptidase domain [PF05903.16, score=19.7]} {Human: ENSG00000127252, HRASLS, HRAS like suppressor, [Score=48.5, Expect=5e-06]} {Celegans: WBGene00009460, ubr-5, UBR E3 ubiquitin ligase homolog, [Score=51.2, Expect=6e-07]} {RNA1509_26414} {RNA1310_26632.1, RNA1509_26414} {RNA1509_26414, RNA815_21681}
14. MligTC455_46261 1407 29.32 Mlig455_058680

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.486

SLC26A4 1.713 - - 0.763 0.950 - - Mlig455_058680 {REF} {Length: 5357} {Pfam: Sulfate permease family [PF00916.22, score=130.2]; STAS domain [PF01740.23, score=75.4]; STAS domain [PF13466.8, score=22.3]} {Human: ENSG00000091137, SLC26A4, solute carrier family 26 member 4, [Score=134, Expect=2e-32]} {Mouse: ENSMUSG00000020651, Slc26a4, solute carrier family 26, member 4, [Score=138, Expect=4e-34]} {Dmel: FBgn0036770, Prestin, [Score=90.1, Expect=1e-18]} {Celegans: WBGene00013963, sulp-8, Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family, [Score=131, Expect=3e-32]} {Smed: dd_Smed_v6_4250_0_2, dd_Smed_v6_4250_0_2, [Score=147, Expect=1e-37]} {RNA1509_45237} {RNA1310_6908.1} {RNA815_3307}
15. MligTC455_04549 296 6.16 Mlig455_047043

Neo: -

Age: logFC(26M/2M)=0.556

Region-enriched R3: 2.204/0.00044
Region-enriched R4: 1.879/0.02998
Region-enriched R5: 1.340/0.03066

TYMP 1.712 - - - 0.952 - 0.760 Mlig455_047043 {REF} {Length: 2149} {TRANSSPLICED} {Pfam: Glycosyl transferase family, a/b domain [PF00591.23, score=114.4]; Glycosyl transferase family, helical bundle domain [PF02885.19, score=55.5]; Pyrimidine nucleoside phosphorylase C-terminal domain [PF07831.15, score=27.3]} {Human: ENSG00000025708, TYMP, thymidine phosphorylase, [RH, Score=324, Expect=7e-106]} {Mouse: ENSMUSG00000022615, Tymp, thymidine phosphorylase, [RH, Score=320, Expect=1e-104]} {Smed: dd_Smed_v6_869_0_1, dd_Smed_v6_869_0_1, [RH, Score=323, Expect=2e-106]} {RNA1509_12879} {RNA1310_13641} {RNA815_1859}
16. MligTC455_53356 1170 24.37 Mlig455_033344, Mlig455_033363

Neo: -

Age: -

Region-enriched R4: 2.114/0.00122
Region-enriched R5: 1.062/0.04423

TMED7 1.687 - - 0.713 0.974 - -

Mlig455_033344 {REF} {Length: 1935} {Pfam: emp24/gp25L/p24 family/GOLD [PF01105.26, score=115.7]} {Human: ENSG00000134970, TMED7, transmembrane p24 trafficking protein 7, [Score=110, Expect=2e-29]} {Mouse: ENSMUSG00000033184, Tmed7, transmembrane p24 trafficking protein 7, [Score=110, Expect=3e-29]} {Dmel: FBgn0030341, p24-1, p24-related-1, [Score=116, Expect=6e-32]} {Celegans: WBGene00019003, F57B10.5, [Score=97.8, Expect=5e-25]} {Smed: dd_Smed_v6_2557_0_1, dd_Smed_v6_2557_0_1, [Score=98.2, Expect=4e-25]} {RNA1509_14712} {RNA1310_32912, RNA1509_14712} {RNA1509_14712, RNA815_16911}

Mlig455_033363 {REF} {Length: 1946} {Pfam: emp24/gp25L/p24 family/GOLD [PF01105.26, score=115.8]} {Human: ENSG00000134970, TMED7, transmembrane p24 trafficking protein 7, [Score=110, Expect=2e-29]} {Mouse: ENSMUSG00000033184, Tmed7, transmembrane p24 trafficking protein 7, [Score=110, Expect=2e-29]} {Dmel: FBgn0030341, p24-1, p24-related-1, [Score=114, Expect=2e-31]} {Celegans: WBGene00019003, F57B10.5, [Score=97.4, Expect=8e-25]} {Smed: dd_Smed_v6_2557_0_1, dd_Smed_v6_2557_0_1, [Score=98.6, Expect=3e-25]} {RNA1509_14712} {RNA1310_32912} {RNA815_16911}
17. MligTC455_48797 154 3.21 Mlig455_054068

Neo: -

Age: -

1.682 - - - 0.971 0.711 - Mlig455_054068 {REF} {Length: 3150} {Dmel: FBgn0051195, CG31195, [Score=164, Expect=5e-43]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [Score=264, Expect=4e-78]} {RNA1509_26475} {RNA1310_2842} {RNA815_1220.1}
18. MligTC455_34132 637 13.26 Mlig455_001144, Mlig455_001306

Neo: -

Age: logFC(26M/2M)=-0.466

Region-enriched R3: 2.010/0.00006
Region-enriched R5: 1.734/0.00009

1.674 - - - 0.959 - 0.715

Mlig455_001144 {REF} {Length: 2159} {Pfam: Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=23.7]; Baculovirus immediate-early protein (IE-0) [PF05290.13, score=23.1]} {RNA1509_32599} {RNA1310_21009} {RNA815_32959}

Mlig455_001306 {REF} {Length: 2354} {Pfam: Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=23.6]} {RNA1310_21009} {RNA815_32959}
19. MligTC455_46262 2748 57.25 Mlig455_010182, Mlig455_058667

Neo: -

Age: logFC(26M/2M)=0.747

RETSAT 1.657 - - 0.706 0.951 - -

Mlig455_010182 {REF} {Length: 7403} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=65.4]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=57.3]; FAD binding domain [PF00890.26, score=39.3]; FAD dependent oxidoreductase [PF12831.9, score=28.5]; FAD dependent oxidoreductase [PF01266.26, score=28.2]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=27.1]; Thi4 family [PF01946.19, score=20.6]; FAD binding domain [PF01494.21, score=20.5]; MCRA family [PF06100.13, score=18.0]} {Human: ENSG00000042445, RETSAT, retinol saturase, [RH, Score=393, Expect=8e-129]} {Mouse: ENSMUSG00000056666, Retsat, retinol saturase (all trans retinol 13,14 reductase), [Score=414, Expect=5e-137]} {RNA1509_1340} {RNA1310_6908.1} {RNA815_3307}

Mlig455_058667 {REF} {Length: 2407} {Pfam: NAD(P)-binding Rossmann-like domain [PF13450.8, score=57.5]; Flavin containing amine oxidoreductase [PF01593.26, score=47.8]; FAD binding domain [PF00890.26, score=36.0]; FAD dependent oxidoreductase [PF12831.9, score=34.2]; FAD dependent oxidoreductase [PF01266.26, score=30.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=25.9]; Thi4 family [PF01946.19, score=20.7]; FAD binding domain [PF01494.21, score=20.6]; MCRA family [PF06100.13, score=18.2]} {Human: ENSG00000042445, RETSAT, retinol saturase, [Score=300, Expect=2e-93]} {Mouse: ENSMUSG00000056666, Retsat, retinol saturase (all trans retinol 13,14 reductase), [Score=318, Expect=6e-101]} {RNA1509_1340} {RNA1310_6908.1} {RNA815_3307}
20. MligTC455_51472 403 8.39 Mlig455_010959

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.299

Region-enriched R3: 1.461/0.02106

M6PR 0.979 - - - 0.979 - - Mlig455_010959 {REF} {Length: 4037} {Pfam: Autophagy-related protein 27 [PF09451.12, score=58.6]; Mannose-6-phosphate receptor [PF02157.17, score=41.6]; Cation-independent mannose-6-phosphate receptor repeat [PF00878.20, score=21.7]} {Human: ENSG00000003056, M6PR, mannose-6-phosphate receptor, cation dependent, [Score=47.4, Expect=1e-05]} {Smed: dd_Smed_v6_1447_0_1, dd_Smed_v6_1447_0_1, [Score=84.3, Expect=5e-19]} {RNA1509_55890} {RNA1310_19118.2, RNA1509_55890} {RNA1509_55890, RNA815_12450}
21. MligTC455_53355 1190 24.78 Mlig455_033338, Mlig455_033357

Neo: -

Age: -

Region-enriched R4: 1.851/0.00149

0.97 - - - 0.970 - -

Mlig455_033338 {REF} {Length: 1291} {RNA1509_14712, RNA1509_46611} {RNA1310_36401.2, RNA1509_46611} {RNA1509_46611, RNA815_17710}

Mlig455_033357 {REF} {Length: 973} {TRANSSPLICED} {RNA1509_14712} {RNA1310_36401.2} {RNA815_17710}
22. MligTC455_18116 1101 22.93 Mlig455_034507

Neo: -

Age: -

Region-enriched R6: 2.069/0.00170
Region-enriched R5: 1.877/0.00089

AP2S1 0.965 - - - 0.965 - - Mlig455_034507 {REF} {Length: 3004} {TRANSSPLICED} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=204.0]} {Human: ENSG00000042753, AP2S1, adaptor related protein complex 2 subunit sigma 1, [RH, Score=269, Expect=3e-94]} {Mouse: ENSMUSG00000008036, Ap2s1, adaptor-related protein complex 2, sigma 1 subunit, [RH, Score=269, Expect=2e-94]} {Dmel: FBgn0043012, AP-2sigma, Adaptor Protein complex 2, sigma subunit, [RH, Score=265, Expect=7e-93]} {Celegans: WBGene00000157, aps-2, AdaPtin, Small chain (Clathrin associated complex), [RH, Score=268, Expect=2e-94]} {Smed: dd_Smed_v6_3529_0_1, dd_Smed_v6_3529_0_1, [RH, Score=257, Expect=6e-90]} {RNA1509_11642, RNA1509_3682, RNA1509_37240, RNA1509_53443, RNA1509_60138, RNA1509_8028} {RNA1310_34747, RNA1509_11642, RNA1509_3682, RNA1509_53443, RNA1509_60138, RNA1509_8028} {RNA1509_11642, RNA1509_3682, RNA1509_53443, RNA1509_60138, RNA1509_8028, RNA815_7668.1}
23. MligTC455_18117 1092 22.75 Mlig455_066275

Neo: -

Age: logFC(26M/2M)=0.355

Region-enriched R6: 2.041/0.00226
Region-enriched R5: 1.905/0.00060

AP2S1 0.965 - - - 0.965 - - Mlig455_066275 {REF} {Length: 1943} {TRANSSPLICED} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=204.0]} {Human: ENSG00000042753, AP2S1, adaptor related protein complex 2 subunit sigma 1, [RH, Score=269, Expect=3e-94]} {Mouse: ENSMUSG00000008036, Ap2s1, adaptor-related protein complex 2, sigma 1 subunit, [RH, Score=269, Expect=2e-94]} {Dmel: FBgn0043012, AP-2sigma, Adaptor Protein complex 2, sigma subunit, [RH, Score=265, Expect=7e-93]} {Celegans: WBGene00000157, aps-2, AdaPtin, Small chain (Clathrin associated complex), [RH, Score=268, Expect=2e-94]} {Smed: dd_Smed_v6_3529_0_1, dd_Smed_v6_3529_0_1, [RH, Score=257, Expect=6e-90]} {RNA1509_11775, RNA1509_37240} {RNA1310_34747, RNA1509_11775, RNA1509_37240} {RNA1509_11775, RNA1509_37240, RNA815_7668.1}
24. MligTC455_45385 1307 27.23 Mlig455_045374

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.488

Region-enriched R3: 1.834/0.00162
Region-enriched R5: 1.310/0.01840

PPP1R3C 0.965 - - - 0.965 - - Mlig455_045374 {REF} {Length: 1627} {Pfam: Carbohydrate/starch-binding module (family 21) [PF03370.15, score=36.6]; Starch/carbohydrate-binding module (family 53) [PF16760.7, score=33.7]} {Human: ENSG00000119938, PPP1R3C, protein phosphatase 1 regulatory subunit 3C, [Score=53.1, Expect=2e-07]} {RNA1509_11258, RNA1509_19500, RNA1509_40029} {RNA1310_23008, RNA1509_11258, RNA1509_19500, RNA1509_40029} {RNA1509_11258, RNA1509_19500, RNA1509_40029, RNA815_7814}
25. MligTC455_12266 346 7.21 Mlig455_020411

Neo: -

Age: logFC(26M/2M)=-0.494

Region-enriched R3: 3.965/0.00021
Region-enriched R4: 2.568/0.04581
Region-enriched R5: 2.399/0.04753

0.964 - - - 0.964 - - Mlig455_020411 {REF} {Length: 1997} {RNA1509_10012} {RNA1310_23404.1} {RNA815_8343.2}
26. MligTC455_43923 1485 30.93 Mlig455_051179

Neo: -

Age: -

Region-enriched R3: 2.085/0.00351

SLC5A9 0.964 - - - 0.964 - - Mlig455_051179 {REF} {Length: 3805} {Pfam: Sodium:solute symporter family [PF00474.19, score=204.7]} {Human: ENSG00000117834, SLC5A9, solute carrier family 5 member 9, [Score=384, Expect=2e-126]; ENSG00000100170, SLC5A1, solute carrier family 5 member 1, [Score=370, Expect=4e-123]} {Mouse: ENSMUSG00000028544, Slc5a9, solute carrier family 5 (sodium/glucose cotransporter), member 9, [Score=392, Expect=1e-129]; ENSMUSG00000011034, Slc5a1, solute carrier family 5 (sodium/glucose cotransporter), member 1, [Score=384, Expect=5e-127]} {Smed: dd_Smed_v6_6663_0_1, dd_Smed_v6_6663_0_1, [Score=478, Expect=1e-163]} {RNA1509_1500, RNA1509_19405} {RNA1310_2456.1, RNA1509_1500, RNA1509_19405} {RNA1509_1500, RNA1509_19405, RNA815_1533}
27. MligTC455_50788 55 1.14 Mlig455_001945

Neo: -

Age: Down-Up-Up

Region-enriched R4: 4.857/0.00120
Region-enriched R5: 3.283/0.00685

GATA6 0.963 - - - 0.963 - - Mlig455_001945 {REF} {Length: 1855} {tRNA: Val(CAC),pseudo, score=26.6} {Pfam: GATA zinc finger [PF00320.29, score=52.2]; TFIIB zinc-binding [PF08271.14, score=20.7]} {Human: ENSG00000141448, GATA6, GATA binding protein 6, [Score=87.8, Expect=1e-18]; ENSG00000136574, GATA4, GATA binding protein 4, [Score=87.0, Expect=2e-18]; ENSG00000285109, GATA4, GATA binding protein 4, [Score=87.0, Expect=2e-18]} {Mouse: ENSMUSG00000005836, Gata6, GATA binding protein 6, [Score=87.0, Expect=2e-18]; ENSMUSG00000021944, Gata4, GATA binding protein 4, [Score=85.5, Expect=4e-18]} {Dmel: FBgn0032223, GATAd, [RH, Score=87.0, Expect=1e-18]} {Celegans: WBGene00001249, elt-1, Transcription factor elt-1, [Score=83.2, Expect=1e-17]} {Smed: dd_Smed_v6_4075_0_1, dd_Smed_v6_4075_0_1, [Score=80.5, Expect=9e-17]} {RNA1509_47157} {RNA1310_45834} {RNA815_33962}
28. MligTC455_16368 545 11.35 Mlig455_024319

Neo: -

Age: -

ZNF628 0.962 0.962 - - - - - Mlig455_024319 {REF} {Length: 4468} {TRANSSPLICED} {Pfam: Zinc-finger double domain [PF13465.8, score=45.6]; Zinc finger, C2H2 type [PF00096.28, score=37.3]; C2H2-type zinc finger [PF13894.8, score=31.3]} {Human: ENSG00000197483, ZNF628, zinc finger protein 628, [Score=98.6, Expect=4e-21]; ENSG00000130856, ZNF236, zinc finger protein 236, [Score=98.6, Expect=5e-21]; ENSG00000152454, ZNF256, zinc finger protein 256, [Score=98.6, Expect=3e-21]; ENSG00000122386, ZNF205, zinc finger protein 205, [Score=95.5, Expect=3e-20]; ENSG00000178187, ZNF454, zinc finger protein 454, [Score=95.1, Expect=3e-20]; ENSG00000141040, ZNF287, zinc finger protein 287, [Score=94.7, Expect=6e-20]; ENSG00000102870, ZNF629, zinc finger protein 629, [Score=94.7, Expect=6e-20]} {Mouse: ENSMUSG00000041258, Zfp236, zinc finger protein 236, [Score=97.8, Expect=6e-21]; ENSMUSG00000074406, Zfp628, zinc finger protein 628, [Score=95.9, Expect=2e-20]; ENSMUSG00000045639, Zfp629, zinc finger protein 629, [Score=95.9, Expect=2e-20]; ENSMUSG00000072915, Gm12258, predicted gene 12258, [Score=95.1, Expect=8e-23]; ENSMUSG00000093910, Zfp853, zinc finger protein 853, [Score=95.1, Expect=2e-20]; ENSMUSG00000058291, Zfp68, zinc finger protein 68, [Score=94.7, Expect=4e-20]; ENSMUSG00000059897, Zfp930, zinc finger protein 930, [Score=94.7, Expect=2e-20]; ENSMUSG00000048728, Zfp454, zinc finger protein 454, [Score=93.2, Expect=1e-19]} {Dmel: FBgn0035625, Blimp-1, [Score=92.8, Expect=1e-19]} {Celegans: WBGene00000483, che-1, Transcription factor che-1, [Score=87.4, Expect=5e-19]} {Smed: dd_Smed_v6_85977_0_1, dd_Smed_v6_85977_0_1, [Score=97.4, Expect=9e-24]} {RNA1509_14204, RNA1509_40122} {RNA1310_11199, RNA1509_14204, RNA1509_40122} {RNA1509_14204, RNA1509_40122, RNA815_8539.1}
29. MligTC455_13282 95 1.99 Mlig455_021294

Neo: -

Age: Down-Up-Down

0.96 - - - 0.960 - - Mlig455_021294 {REF} {Length: 840} {NoTransDecoderORF} {RNA1310_63724} {RNA815_38056}
30. MligTC455_38456 1125 23.43 Mlig455_065743

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.509

Region-enriched R3: 1.173/0.00420

PHYH 0.953 - - - 0.953 - - Mlig455_065743 {REF} {Length: 1936} {TRANSSPLICED} {Pfam: Phytanoyl-CoA dioxygenase (PhyH) [PF05721.15, score=143.6]} {Human: ENSG00000107537, PHYH, phytanoyl-CoA 2-hydroxylase, [RH, Score=332, Expect=3e-113]} {Mouse: ENSMUSG00000026664, Phyh, phytanoyl-CoA hydroxylase, [RH, Score=327, Expect=1e-111]} {Dmel: FBgn0037819, CG14688, [Score=48.1, Expect=4e-06]} {Celegans: WBGene00014000, ZK550.6, Probable phytanoyl-CoA dioxygenase, [RH, Score=331, Expect=6e-114]} {Smed: dd_Smed_v6_8029_0_1, dd_Smed_v6_8029_0_1, [Score=54.7, Expect=1e-08]} {RNA1509_44457, RNA1509_9637} {RNA1310_18056.1, RNA1509_44457, RNA1509_9637} {RNA1509_44457, RNA1509_9637, RNA815_7280.1}
31. MligTC455_40772 633 13.18 Mlig455_000911

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.927/0.00277

BEST3 0.953 - - - 0.953 - - Mlig455_000911 {REF} {Length: 2760} {Pfam: Bestrophin, RFP-TM, chloride channel [PF01062.23, score=178.5]} {Human: ENSG00000127325, BEST3, bestrophin 3, [Score=159, Expect=2e-41]} {Mouse: ENSMUSG00000020169, Best3, bestrophin 3, [Score=162, Expect=2e-42]} {Dmel: FBgn0040238, Best1, Bestrophin 1, [Score=190, Expect=3e-52]} {Celegans: WBGene00015286, best-3, Bestrophin homolog, [Score=160, Expect=2e-42]} {Smed: dd_Smed_v6_2084_0_1, dd_Smed_v6_2084_0_1, [RH, Score=322, Expect=8e-105]} {RNA1509_44952} {RNA1310_13111} {RNA815_15310}
32. MligTC455_41085 296 6.17 Mlig455_017879

Neo: -

Age: logFC(26M/2M)=-0.440

Region-enriched R3: 2.264/0.01110
Region-enriched R4: 2.258/0.02365
Region-enriched R5: 1.843/0.01824

SULT1C4 0.953 - - - 0.953 - - Mlig455_017879 {REF} {Length: 1911} {Pfam: Sulfotransferase domain [PF00685.29, score=122.3]; Sulfotransferase family [PF13469.8, score=23.0]} {Human: ENSG00000198075, SULT1C4, sulfotransferase family 1C member 4, [Score=105, Expect=1e-25]; ENSG00000173597, SULT1B1, sulfotransferase family 1B member 1, [Score=105, Expect=1e-25]; ENSG00000138068, SULT6B1, sulfotransferase family 6B member 1, [Score=101, Expect=2e-24]} {Mouse: ENSMUSG00000029269, Sult1b1, sulfotransferase family 1B, member 1, [Score=107, Expect=1e-26]; ENSMUSG00000003271, Sult2b1, sulfotransferase family, cytosolic, 2B, member 1, [Score=103, Expect=8e-25]; ENSMUSG00000048473, Sult6b2, sulfotransferase family 6B, member 2, [Score=102, Expect=6e-25]; ENSMUSG00000038045, Sult6b1, sulfotransferase family, cytosolic, 6B, member 1, [Score=102, Expect=1e-24]} {Dmel: FBgn0033887, St4, Sulfotransferase 4, [Score=88.6, Expect=1e-19]} {Smed: dd_Smed_v6_7766_0_1, dd_Smed_v6_7766_0_1, [Score=73.9, Expect=5e-15]} {RNA1509_50923} {RNA1310_21135, RNA1509_50923} {RNA1509_50923, RNA815_12979}
33. MligTC455_41521 1793 37.36 Mlig455_057588

Neo: -

Age: -

Region-enriched R5: 1.375/0.00000
Region-enriched R3: 1.257/0.00033
Region-enriched R4: 1.049/0.01657

0.953 - - - 0.953 - - Mlig455_057588 {REF} {Length: 2069} {TRANSSPLICED} {RNA1509_22303, RNA1509_3842, RNA1509_41783, RNA1509_9152} {RNA1310_16812.1, RNA1509_22303, RNA1509_3842, RNA1509_41783, RNA1509_9152} {RNA1509_22303, RNA1509_3842, RNA1509_41783, RNA1509_9152, RNA815_17534}
34. MligTC455_42301 167 3.48 Mlig455_003238

Neo: -

Age: Up-Down-Down

0.951 0.951 - - - - - Mlig455_003238 {REF} {Length: 1349} {NoTransDecoderORF} {RNA1509_47710} {RNA1310_102904} {RNA815_7856.3}
35. MligTC455_44815 2132 44.41 Mlig455_020482

Neo: -

Age: -

0.951 - - - 0.951 - - Mlig455_020482 {REF} {Length: 1449} {TRANSSPLICED} {Mouse: ENSMUSG00000024675, Ms4a4c, membrane-spanning 4-domains, subfamily A, member 4C, [Score=49.3, Expect=4e-07]} {RNA1509_22973, RNA1509_26766, RNA1509_27903, RNA1509_46181, RNA1509_49284, RNA1509_51218, RNA1509_53021, RNA1509_6951} {RNA1310_23891.1, RNA1509_22973, RNA1509_26766, RNA1509_27903, RNA1509_46181, RNA1509_49284, RNA1509_51218, RNA1509_53021, RNA1509_6951} {RNA1509_22973, RNA1509_26766, RNA1509_27903, RNA1509_46181, RNA1509_49284, RNA1509_51218, RNA1509_53021, RNA1509_6951, RNA815_14546}
36. MligTC455_24044 321 6.69 Mlig455_042095

Neo: -

Age: logFC(26M/2M)=0.284

RAB11A 0.95 - - - - 0.950 - Mlig455_042095 {REF} {Length: 2333} {Pfam: Ras family [PF00071.24, score=185.5]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=112.7]; ADP-ribosylation factor family [PF00025.23, score=44.9]; 50S ribosome-binding GTPase [PF01926.25, score=27.9]; Signal recognition particle receptor beta subunit [PF09439.12, score=21.9]; Ethanolamine utilisation - propanediol utilisation [PF10662.11, score=20.4]; Elongation factor Tu GTP binding domain [PF00009.29, score=18.9]} {Human: ENSG00000103769, RAB11A, RAB11A, member RAS oncogene family, [Score=213, Expect=2e-69]; ENSG00000185236, RAB11B, RAB11B, member RAS oncogene family, [Score=206, Expect=7e-67]} {Mouse: ENSMUSG00000004771, Rab11a, RAB11A, member RAS oncogene family, [Score=213, Expect=1e-69]; ENSMUSG00000077450, Rab11b, RAB11B, member RAS oncogene family, [Score=206, Expect=4e-67]} {Dmel: FBgn0015790, Rab11, [Score=213, Expect=5e-70]} {Celegans: WBGene00004274, rab-11.1, Ras-related protein rab-11.1, [Score=209, Expect=2e-68]} {Smed: dd_Smed_v6_867_0_1, dd_Smed_v6_867_0_1, [Score=200, Expect=7e-65]} {RNA1509_31963, RNA1509_52120} {RNA1310_28163, RNA1509_31963, RNA1509_52120} {RNA1509_31963, RNA1509_52120, RNA815_20566}
37. MligTC455_29312 242 5.04 Mlig455_024665

Neo: -

Age: -

Region-enriched R3: 2.630/0.00156
Region-enriched R5: 1.791/0.03664

SLC22A6 0.95 - - - 0.950 - - Mlig455_024665 {REF} {Length: 4159} {Pfam: Sugar (and other) transporter [PF00083.26, score=112.3]; Major Facilitator Superfamily [PF07690.18, score=83.6]} {Human: ENSG00000197901, SLC22A6, solute carrier family 22 member 6, [Score=184, Expect=1e-50]} {Mouse: ENSMUSG00000024650, Slc22a6, solute carrier family 22 (organic anion transporter), member 6, [Score=174, Expect=4e-47]; ENSMUSG00000074028, Slc22a13, solute carrier family 22 (organic cation transporter), member 13, [Score=172, Expect=3e-46]; ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=170, Expect=2e-45]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=176, Expect=8e-48]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=139, Expect=6e-35]} {Smed: dd_Smed_v6_1159_0_1, dd_Smed_v6_1159_0_1, [Score=132, Expect=7e-33]} {RNA1509_13135, RNA1509_47373, RNA1509_50772} {RNA1310_6359.1, RNA1509_13135, RNA1509_47373, RNA1509_50772} {RNA1509_13135, RNA1509_47373, RNA1509_50772, RNA815_24636}
38. MligTC455_44645 563 11.72 Mlig455_070220

Neo: -

Age: -

SLC28A1 0.95 - - - 0.950 - - Mlig455_070220 {REF} {Length: 2524} {Pfam: Na+ dependent nucleoside transporter C-terminus [PF07662.15, score=236.4]; Na+ dependent nucleoside transporter N-terminus [PF01773.22, score=73.8]; Nucleoside recognition [PF07670.16, score=23.7]} {Human: ENSG00000156222, SLC28A1, solute carrier family 28 member 1, [RH, Score=377, Expect=7e-123]; ENSG00000137860, SLC28A2, solute carrier family 28 member 2, [RH, Score=369, Expect=3e-119]} {Mouse: ENSMUSG00000027219, Slc28a2, solute carrier family 28 (sodium-coupled nucleoside transporter), member 2, [RH, Score=385, Expect=6e-126]; ENSMUSG00000025726, Slc28a1, solute carrier family 28 (sodium-coupled nucleoside transporter), member 1, [RH, Score=377, Expect=1e-122]} {Dmel: FBgn0025709, CNT2, Concentrative nucleoside transporter 2, [Score=300, Expect=5e-94]} {Celegans: WBGene00017868, slc-28.2, Sodium/nucleoside cotransporter, [RH, Score=240, Expect=2e-71]} {Smed: dd_Smed_v6_3508_0_1, dd_Smed_v6_3508_0_1, [Score=456, Expect=3e-154]} {RNA1509_20711, RNA1509_21619, RNA1509_48971} {RNA1310_7732, RNA1509_20711, RNA1509_21619, RNA1509_48971} {RNA1509_20711, RNA1509_21619, RNA1509_48971, RNA815_2578}

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