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Results for MligTC455_16415

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_16415 197 4.10 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

ROR1 Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}

Cumulative graph for MligTC455_16415

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -4.618 2.72 0.99967 1.00000
RegionR2 4.276 2.72 0.00034 0.00982
RegionR3 1.018 2.72 0.40114 0.92940
RegionR4 -0.599 2.72 0.89127 1.00000
RegionR5 1.178 2.72 0.30814 0.64593
RegionR6 0.849 2.72 0.47352 1.00000
RegionR7 2.004 2.72 0.14125 0.70271
RegionR8 -4.107 2.72 0.99956 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.648 2.72 0.99995 1.00000
RegenerationR2 0.379 2.72 0.54529 0.89057
RegenerationR3 -0.412 2.72 0.65065 0.92925
RegenerationR4 -0.489 2.72 0.68701 0.94805
RegenerationR5 -1.193 2.72 0.15826 0.58028
RegenerationR6 -0.771 2.72 0.43758 0.76229
RegenerationBL 0.204 2.72 0.75129 1.00000
RegenerationTP 1.217 2.72 0.55662 0.93690


Genes with expression patterns similar to MligTC455_16415

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_16415 197 4.1 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

ROR1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}
2. MligTC455_16416 290 6.04 Mlig455_000468

Neo: -

Age: -

Region-enriched R2: 2.225/0.04782

ROR1 5.794 0.939 0.915 0.958 0.995 0.999 0.988 Mlig455_000468 {REF} {Length: 2686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=208.1]; Protein kinase domain [PF00069.27, score=77.3]; Kringle domain [PF00051.20, score=19.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=300, Expect=1e-89]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=295, Expect=2e-87]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=281, Expect=2e-82]} {Dmel: FBgn0010407, Ror, [Score=259, Expect=2e-76]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=217, Expect=2e-60]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=328, Expect=1e-100]} {RNA1509_35395} {RNA1310_13558} {RNA815_27446}
3. MligTC455_38682 102 2.12 Mlig455_039641

Neo: -

Age: -

Region-enriched R2: 6.138/0.02363

SLC18A3 5.577 0.940 0.847 0.914 0.934 0.976 0.966 Mlig455_039641 {REF} {Length: 3925} {Pfam: Major Facilitator Superfamily [PF07690.18, score=147.1]; Sugar (and other) transporter [PF00083.26, score=29.0]; LacY proton/sugar symporter [PF01306.21, score=20.2]} {Human: ENSG00000187714, SLC18A3, solute carrier family 18 member A3, [RH, Score=469, Expect=9e-161]} {Mouse: ENSMUSG00000100241, Slc18a3, solute carrier family 18 (vesicular monoamine), member 3, [RH, Score=469, Expect=1e-160]} {Dmel: FBgn0270928, VAChT, Vesicular acetylcholine transporter, [RH, Score=513, Expect=2e-177]} {Celegans: WBGene00006756, unc-17, Vesicular acetylcholine transporter unc-17, [RH, Score=486, Expect=2e-167]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [RH, Score=563, Expect=0.0]} {RNA1310_28397} {RNA815_32284.1}
4. MligTC455_49491 136 2.83 Mlig455_054796

Neo: -

Age: -

Region-enriched R2: 7.065/0.00003

5.52 0.940 0.889 0.910 0.871 0.912 0.998 Mlig455_054796 {REF} {Length: 1567} {RNA1509_22234} {RNA1310_23973} {RNA815_10832}
5. MligTC455_33040 203 4.23 Mlig455_032497

Neo: -

Age: logFC(26M/2M)=0.515

Region-enriched R2: 4.005/0.00408

PKD2L1 5.514 0.898 0.912 0.889 0.921 0.916 0.978 Mlig455_032497 {REF} {Length: 3318} {Pfam: Polycystin cation channel [PF08016.14, score=293.1]; Ion transport protein [PF00520.33, score=39.7]} {Human: ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [Score=236, Expect=4e-66]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=261, Expect=3e-73]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=131, Expect=5e-31]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=180, Expect=1e-47]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=641, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
6. MligTC455_42376 61 1.27 Mlig455_069890

Neo: -

Age: -

5.462 0.954 0.775 0.911 0.939 0.953 0.930 Mlig455_069890 {REF} {Length: 630} {TRANSSPLICED} {Pfam: PAN domain [PF00024.28, score=26.1]} {RNA1509_53783} {RNA1310_37190} {RNA815_24434}
7. MligTC455_27650 178 3.72 Mlig455_017720

Neo: -

Age: logFC(26M/2M)=-0.928

Region-enriched R2: 3.586/0.00082

ADAM33 5.454 0.977 0.904 0.956 0.874 0.797 0.946 Mlig455_017720 {REF} {Length: 4499} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=124.3]; Disintegrin [PF00200.25, score=66.8]; Metallo-peptidase family M12 [PF13688.8, score=62.2]; ADAM cysteine-rich [PF08516.14, score=61.3]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=33.1]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=237, Expect=1e-64]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [Score=233, Expect=2e-63]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=230, Expect=2e-62]; ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=228, Expect=4e-61]; ENSG00000069206, ADAM7, ADAM metallopeptidase domain 7, [Score=226, Expect=4e-61]; ENSG00000042980, ADAM28, ADAM metallopeptidase domain 28, [Score=226, Expect=4e-61]} {Mouse: ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [RH, Score=248, Expect=4e-69]; ENSMUSG00000050190, Gm5346, predicted gene 5346, [RH, Score=239, Expect=3e-66]} {Dmel: FBgn0265140, Meltrin, [RH, Score=288, Expect=1e-79]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=246, Expect=3e-67]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=225, Expect=3e-60]} {RNA1509_7654} {RNA1310_9319.1} {RNA815_4173.1}
8. MligTC455_34369 112 2.34 Mlig455_015308, Mlig455_015354, Mlig455_036248, Mlig455_068737, Mlig455_070110

Neo: -

Age: Up-Down-Up

Region-enriched R2: 5.462/0.00546

5.424 0.924 0.918 0.924 0.822 0.980 0.856

Mlig455_015308 {REF} {Length: 1459} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.9]} {RNA1310_34740} {RNA815_15663}

Mlig455_015354 {REF} {Length: 1446} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=66.3]; Sialidase, N-terminal domain [PF02973.18, score=18.5]} {RNA1310_34740} {RNA815_15663}

Mlig455_036248 {REF} {Length: 2111} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=120.9]; Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=28.5]; PAN domain [PF00024.28, score=19.9]} {RNA1509_45496} {RNA1310_2539.1} {RNA815_252.1}

Mlig455_068737 {REF} {Length: 1096} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=68.3]; Sialidase, N-terminal domain [PF02973.18, score=19.9]} {RNA1310_34740} {RNA815_37905}

Mlig455_070110 {REF} {Length: 1340} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=109.6]} {RNA1509_32599} {RNA1310_1659} {RNA815_252.1}
9. MligTC455_31853 516 10.74 Mlig455_014495, Mlig455_014514, Mlig455_054434

Neo: -

Age: -

5.406 0.910 0.776 0.914 0.977 0.953 0.876

Mlig455_014495 {REF} {Length: 3100} {RNA1509_20117} {RNA1310_5956.1, RNA1509_20117} {RNA1509_20117, RNA815_18508}

Mlig455_014514 {REF} {Length: 3051} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.7, Expect=2e-19]} {RNA1509_20117} {RNA1310_5956.1} {RNA815_18508}

Mlig455_054434 {REF} {Length: 4026} {Pfam: Late embryogenesis abundant protein [PF03242.15, score=21.0]} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.4, Expect=2e-20]} {RNA1509_20117} {RNA1310_8165} {RNA815_23492}
10. MligTC455_31164 572 11.91 Mlig455_029609, Mlig455_045673

Neo: -

Age: -

5.38 0.772 0.810 0.895 0.958 0.970 0.975

Mlig455_029609 {REF} {Length: 746} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=39.4]} {Smed: dd_Smed_v6_22533_0_1, dd_Smed_v6_22533_0_1, [Score=48.5, Expect=1e-06]} {RNA1310_96354} {RNA815_44390}

Mlig455_045673 {REF} {Length: 2025} {RNA1509_21720} {RNA1310_14760} {RNA815_24583}
11. MligTC455_27025 706 14.7 Mlig455_054786, Mlig455_054878

Neo: -

Age: -

Region-enriched R2: 3.519/0.00005

CD82 5.362 0.933 0.910 0.784 0.851 0.959 0.925

Mlig455_054786 {REF} {Length: 2796} {Pfam: Tetraspanin family [PF00335.22, score=142.8]} {Human: ENSG00000085117, CD82, CD82 molecule, [RH, Score=86.3, Expect=4e-19]} {Mouse: ENSMUSG00000027215, Cd82, CD82 antigen, [RH, Score=94.0, Expect=3e-22]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=98.6, Expect=6e-24]} {Celegans: WBGene00006632, tsp-6, Tetraspanin, [Score=74.7, Expect=1e-15]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [RH, Score=160, Expect=2e-47]} {RNA1509_20389, RNA1509_43644, RNA1509_56428} {RNA1310_8032.1, RNA1509_20389, RNA1509_43644, RNA1509_56428} {RNA1509_20389, RNA1509_43644, RNA1509_56428, RNA815_3380.1}

Mlig455_054878 {REF} {Length: 4398} {Pfam: Tetraspanin family [PF00335.22, score=143.7]} {Human: ENSG00000085117, CD82, CD82 molecule, [RH, Score=84.7, Expect=2e-18]} {Mouse: ENSMUSG00000027215, Cd82, CD82 antigen, [RH, Score=92.4, Expect=2e-21]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=99.8, Expect=4e-24]} {Celegans: WBGene00006643, tsp-17, TetraSPanin family, [RH, Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [RH, Score=160, Expect=2e-47]} {RNA1509_56428} {RNA1310_8032.2} {RNA815_3380.1}
12. MligTC455_35773 89 1.86 Mlig455_064449, Mlig455_064456

Neo: -

Age: -

Region-enriched R2: 5.198/0.00725

NANP 5.254 0.967 0.801 0.930 0.901 0.924 0.731

Mlig455_064449 {REF} {Length: 503} {NoTransDecoderORF} {RNA1310_53432.2}

Mlig455_064456 {REF} {Length: 3122} {Pfam: Haloacid dehalogenase-like hydrolase [PF13419.8, score=56.3]; haloacid dehalogenase-like hydrolase [PF00702.28, score=55.3]; HAD-hyrolase-like [PF13242.8, score=44.6]} {Human: ENSG00000170191, NANP, N-acetylneuraminic acid phosphatase, [RH, Score=47.4, Expect=8e-06]} {Mouse: ENSMUSG00000053916, Nanp, N-acetylneuraminic acid phosphatase, [RH, Score=48.5, Expect=2e-06]} {Celegans: WBGene00018465, F45E1.4, [RH, Score=147, Expect=4e-43]} {Smed: dd_Smed_v6_2813_0_3, dd_Smed_v6_2813_0_3, [Score=174, Expect=2e-50]} {RNA1310_59243} {RNA815_62364}
13. MligTC455_42510 125 2.6 Mlig455_025998, Mlig455_070424

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.702

5.232 0.847 0.747 0.987 0.786 0.871 0.994

Mlig455_025998 {REF} {Length: 1369} {RNA1310_73875.1}

Mlig455_070424 {REF} {Length: 1082} {RNA1310_73875.1}
14. MligTC455_46605 388 8.08 Mlig455_032055

Neo: -

Age: -

Region-specific R2: 4.152

5.143 0.711 0.732 0.896 0.902 0.938 0.964 Mlig455_032055 {REF} {Length: 1416} {RNA1310_44339} {RNA815_20624}
15. MligTC455_19276 1694 35.28 Mlig455_057303

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.711

Region-enriched R2: 6.117/0.00000
Region-enriched R3: 2.663/0.00058

5.134 0.766 0.812 0.759 0.858 0.959 0.980 Mlig455_057303 {REF} {Length: 1196} {Pfam: TATA-binding related factor (TRF) of subunit 20 of Mediator complex [PF08612.13, score=80.6]} {Smed: dd_Smed_v6_9879_0_1, dd_Smed_v6_9879_0_1, [RH, Score=73.9, Expect=1e-15]} {RNA1509_58478} {RNA1310_35292} {RNA815_20171}
16. MligTC455_19030 628 13.08 Mlig455_046052

Neo: -

Age: -

Region-enriched R2: 3.353/0.00000

ADGRL3 5.116 0.894 0.773 0.762 0.720 0.980 0.987 Mlig455_046052 {REF} {Length: 7405} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=104.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=61.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=54.3]; GPCR-Autoproteolysis INducing (GAIN) domain [PF16489.7, score=28.0]} {Human: ENSG00000150471, ADGRL3, adhesion G protein-coupled receptor L3, [Score=157, Expect=8e-38]} {Mouse: ENSMUSG00000037605, Adgrl3, adhesion G protein-coupled receptor L3, [Score=158, Expect=5e-38]} {Dmel: FBgn0033313, Cirl, Calcium-independent receptor for alpha-latrotoxin, [RH, Score=72.4, Expect=5e-12]} {Celegans: WBGene00002251, lat-1, Latrophilin-like protein 1, [Score=107, Expect=5e-23]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=587, Expect=1e-173]} {RNA1509_17130, RNA1509_4023, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867} {RNA1310_254.2, RNA1509_17130, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867} {RNA1509_17130, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867, RNA815_85.1}
17. MligTC455_19278 4335 90.31 Mlig455_057304, Mlig455_070944

Neo: -

Age: logFC(26M/2M)=0.686

Region-specific R2: 5.590

Region-enriched R2: 5.465/0.00000
Region-enriched R3: 2.308/0.00629

CHRNA10 5.079 0.762 0.818 0.702 0.860 0.957 0.980

Mlig455_057304 {REF} {Length: 1001} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=71.6]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=77.0, Expect=2e-16]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=75.9, Expect=4e-16]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=75.5, Expect=6e-16]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=73.9, Expect=2e-15]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=93.6, Expect=2e-22]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=100, Expect=5e-25]} {Smed: dd_Smed_v6_11955_0_1, dd_Smed_v6_11955_0_1, [Score=82.8, Expect=8e-19]} {RNA1509_23115} {RNA1310_34970} {RNA815_15305.1}

Mlig455_070944 {REF} {Length: 1060} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=88.2]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=95.9, Expect=6e-22]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=96.3, Expect=3e-22]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=94.7, Expect=1e-21]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=112, Expect=7e-28]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=118, Expect=4e-30]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=98.6, Expect=2e-23]} {RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1310_34970, RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1509_23115, RNA1509_43907, RNA1509_9432, RNA815_15305.1}
18. MligTC455_54282 74 1.54 Mlig455_020191

Neo: -

Age: -

5.079 0.716 0.787 0.840 0.808 0.940 0.988 Mlig455_020191 {REF} {Length: 937} {RNA1509_48973} {RNA1310_40738.2} {RNA815_31898}
19. MligTC455_24270 71 1.47 Mlig455_005120

Neo: -

Age: -

CHRNA7 5.07 0.780 0.711 0.843 0.784 0.968 0.984 Mlig455_005120 {REF} {Length: 1530} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=115.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=66.6]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=148, Expect=4e-39]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=147, Expect=5e-39]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=4e-38]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=146, Expect=2e-38]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=140, Expect=1e-36]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=135, Expect=5e-34]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=134, Expect=9e-35]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=133, Expect=4e-34]} {RNA1509_43533} {RNA1310_20839.2} {RNA815_22406}
20. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 4.874 0.963 - 0.974 0.981 0.962 0.994

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
21. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 4.82 0.948 - 0.960 0.947 0.980 0.985 Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
22. MligTC455_15492 69 1.44 Mlig455_022488

Neo: -

Age: Down-Up-Up

4.762 0.989 - 0.867 0.944 0.969 0.993 Mlig455_022488 {REF} {Length: 1351} {RNA1310_26051} {RNA815_10966}
23. MligTC455_33039 312 6.51 Mlig455_032494

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.545/0.00267

PKDREJ 4.758 0.938 - 0.937 0.930 0.981 0.972 Mlig455_032494 {REF} {Length: 11952} {Pfam: Polycystin cation channel [PF08016.14, score=289.9]; REJ domain [PF02010.17, score=90.4]; PLAT/LH2 domain [PF01477.25, score=68.4]; PKD domain [PF00801.22, score=57.9]; PKD domain [PF18911.2, score=36.7]; Ion transport protein [PF00520.33, score=36.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=30.0]; WSC domain [PF01822.21, score=23.3]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=267, Expect=1e-70]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=292, Expect=3e-78]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=136, Expect=2e-31]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=297, Expect=4e-80]} {Smed: dd_Smed_v6_15525_0_1, dd_Smed_v6_15525_0_1, [Score=1504, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
24. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

4.717 0.856 - 0.924 0.983 0.956 0.998 Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
25. MligTC455_17464 409 8.52 Mlig455_048989, Mlig455_049006, Mlig455_067762

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.512

Regeneration-downregulated BL: -7.800

Regeneration-depleted BL: -7.800

4.683 - 0.807 0.971 0.966 0.945 0.994

Mlig455_048989 {REF} {Length: 1272} {RNA1310_37715} {RNA815_39767}

Mlig455_049006 {REF} {Length: 1028} {RNA1310_37715} {RNA815_39767}

Mlig455_067762 {REF} {Length: 1353} {RNA1310_37715} {RNA815_39767}
26. MligTC455_40610 165 3.43 Mlig455_064484

Neo: -

Age: -

Region-enriched R2: 5.617/0.00105

4.682 - 0.893 0.960 0.976 0.855 0.998 Mlig455_064484 {REF} {Length: 2931} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=24.9]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [Score=154, Expect=2e-40]} {RNA1509_26568} {RNA1310_9342.1, RNA1509_26568} {RNA1509_26568, RNA815_7018}
27. MligTC455_13963 31 0.64 Mlig455_052027

Neo: -

Age: Down-Up-Down

4.671 0.856 - 0.967 0.891 0.959 0.998 Mlig455_052027 {REF} {Length: 1717} {RNA1509_48973} {RNA1310_34931} {RNA815_59614}
28. MligTC455_19908 490 10.21 Mlig455_047266, Mlig455_047318, Mlig455_069346

Neo: -

Age: logFC(26M/2M)=0.566

4.67 0.849 - 0.886 0.974 0.968 0.993

Mlig455_047266 {REF} {Length: 1728} {Pfam: Glycine rich protein [PF12810.9, score=49.4]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}

Mlig455_047318 {REF} {Length: 2268} {Pfam: Glycine rich protein [PF12810.9, score=36.7]} {RNA1509_28009} {RNA1310_17226, RNA1509_28009} {RNA1509_28009, RNA815_32720}

Mlig455_069346 {REF} {Length: 1953} {Pfam: Glycine rich protein [PF12810.9, score=31.6]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}
29. MligTC455_39890 162 3.37 Mlig455_047281, Mlig455_047331, Mlig455_069333

Neo: -

Age: -

Region-enriched R2: 6.097/0.00148

PLSCR1 4.67 0.855 - 0.966 0.972 0.882 0.995

Mlig455_047281 {REF} {Length: 1404} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_047331 {REF} {Length: 1395} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_069333 {REF} {Length: 1416} {Pfam: Scramblase [PF03803.17, score=248.7]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=226, Expect=1e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=228, Expect=2e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=223, Expect=1e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=224, Expect=2e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=4e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=304, Expect=2e-103]} {RNA1310_29769} {RNA815_41335}
30. MligTC455_49307 122 2.55 Mlig455_055230

Neo: -

Age: -

Region-enriched R2: 4.447/0.04819

ZAN 4.664 0.967 - 0.866 0.926 0.991 0.914 Mlig455_055230 {REF} {Length: 2947} {Pfam: Glycine rich protein [PF12810.9, score=28.6]} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=79.7, Expect=1e-14]} {Mouse: ENSMUSG00000079173, Zan, zonadhesin, [Score=80.1, Expect=7e-15]} {RNA1310_18897} {RNA815_40026}
31. MligTC455_29929 164 3.41 Mlig455_030237, Mlig455_068015

Neo: -

Age: -

Region-enriched R2: 4.901/0.00350

SIX6 4.661 0.923 0.873 - 0.982 0.885 0.998

Mlig455_030237 {REF} {Length: 2545} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.1]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=8e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=6e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=9e-93]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=2e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=2e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}

Mlig455_068015 {REF} {Length: 2713} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.2]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=7e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=5e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=1e-92]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=1e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=1e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}
32. MligTC455_31163 72 1.51 Mlig455_045625

Neo: -

Age: Up-Down-Down

4.66 0.932 - 0.887 0.937 0.924 0.980 Mlig455_045625 {REF} {Length: 1957} {RNA1509_21720} {RNA1310_14760, RNA1509_21720} {RNA1509_21720, RNA815_24583}
33. MligTC455_39096 110 2.29 Mlig455_019781, Mlig455_019803

Neo: -

Age: -

4.653 0.851 - 0.986 0.973 0.845 0.998

Mlig455_019781 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=65.0]} {RNA1310_34740} {RNA815_15663}

Mlig455_019803 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.1]} {RNA1310_34740} {RNA815_15663}
34. MligTC455_41368 369 7.68 Mlig455_007683, Mlig455_020872, Mlig455_020918, Mlig455_020998

Neo: -

Age: -

4.648 0.974 - 0.907 0.969 0.929 0.869

Mlig455_007683 {REF} {Length: 1379} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020872 {REF} {Length: 1217} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020918 {REF} {Length: 1220} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020998 {REF} {Length: 1235} {RNA1310_25040.1} {RNA815_12562.1}
35. MligTC455_38368 107 2.24 Mlig455_026435, Mlig455_044757

Neo: -

Age: Up-Down-Down

SSUH2 4.636 - 0.956 0.836 0.947 0.995 0.902

Mlig455_026435 {REF} {Length: 1789} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [RH, Score=233, Expect=1e-72]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [RH, Score=195, Expect=1e-58]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=117, Expect=3e-29]} {RNA1509_6425} {RNA1310_32434} {RNA815_16161}

Mlig455_044757 {REF} {Length: 883} {TRANSSPLICED} {RNA1509_28356} {RNA1310_61125} {RNA815_53103}
36. MligTC455_45039 168 3.49 Mlig455_040482, Mlig455_040487

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.332/0.02336

4.611 - 0.820 0.984 0.925 0.886 0.996

Mlig455_040482 {REF} {Length: 1774} {RNA1310_20941} {RNA815_45079}

Mlig455_040487 {REF} {Length: 5763} {tRNA: Val(CAC),pseudo, score=20.2} {Celegans: WBGene00022195, Y71H2B.5, [Score=146, Expect=8e-36]} {Smed: dd_Smed_v6_16438_0_2, dd_Smed_v6_16438_0_2, [Score=188, Expect=1e-49]} {RNA1509_21228} {RNA1310_20941} {RNA815_45079}
37. MligTC455_03841 920 19.16 Mlig455_018790, Mlig455_048140

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.474

Region-enriched R2: 5.915/0.00081

NKX2-1, NKX2-4 4.596 - 0.901 0.815 0.967 0.996 0.917

Mlig455_018790 {REF} {Length: 2203} {Pfam: Homeodomain [PF00046.31, score=72.7]} {Human: ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]; ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=2e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=8e-47]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=134, Expect=2e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=191, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401} {RNA815_21584}

Mlig455_048140 {REF} {Length: 2218} {Pfam: Homeodomain [PF00046.31, score=72.5]} {Human: ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=3e-39]; ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=144, Expect=6e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=2e-46]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=136, Expect=1e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=193, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401, RNA1509_12761} {RNA1509_12761, RNA815_21584}
38. MligTC455_32644 41 0.86 Mlig455_043770, Mlig455_043786

Neo: -

Age: -

Region-enriched R2: 6.705/0.00336

4.594 0.847 - 0.965 0.936 0.848 0.998

Mlig455_043770 {REF} {Length: 1011} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.8, Expect=3e-11]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}

Mlig455_043786 {REF} {Length: 1348} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
39. MligTC455_18579 143 2.97 Mlig455_047208, Mlig455_048469

Neo: -

Age: -

GRIK2, GRIK3 4.583 0.774 - 0.944 0.875 0.996 0.994

Mlig455_047208 {REF} {Length: 5413} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=92.5]; Ligand-gated ion channel [PF00060.28, score=84.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=49.2]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=194, Expect=2e-50]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=193, Expect=5e-50]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=192, Expect=2e-49]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=192, Expect=2e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=191, Expect=3e-49]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=194, Expect=1e-50]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=194, Expect=3e-50]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=191, Expect=2e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=191, Expect=2e-49]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=188, Expect=2e-48]} {Dmel: FBgn0038837, CG3822, [Score=185, Expect=9e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=200, Expect=7e-53]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=341, Expect=5e-106]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}

Mlig455_048469 {REF} {Length: 3740} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=95.9]; Ligand-gated ion channel [PF00060.28, score=82.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=51.5]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=190, Expect=6e-50]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=187, Expect=5e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=185, Expect=3e-48]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=184, Expect=1e-47]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=189, Expect=7e-50]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=187, Expect=6e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=185, Expect=2e-48]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=183, Expect=9e-48]} {Dmel: FBgn0038837, CG3822, [Score=183, Expect=4e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=183, Expect=3e-48]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=338, Expect=6e-108]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}
40. MligTC455_48522 94 1.96 Mlig455_032491

Neo: -

Age: -

Region-enriched R2: 4.888/0.01251

4.577 0.901 - 0.920 0.833 0.975 0.948 Mlig455_032491 {REF} {Length: 2169} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=47.3]} {Dmel: FBgn0015776, nrv1, nervana 1, [Score=55.5, Expect=2e-08]} {RNA1310_12303} {RNA815_10417}
41. MligTC455_43979 188 3.92 Mlig455_000082, Mlig455_063749

Neo: -

Age: -

GHSR 4.573 0.856 - 0.964 0.975 0.780 0.998

Mlig455_000082 {REF} {Length: 1342} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=53.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=18.2]} {Human: ENSG00000121853, GHSR, growth hormone secretagogue receptor, [Score=52.0, Expect=7e-07]} {Mouse: ENSMUSG00000051136, Ghsr, growth hormone secretagogue receptor, [Score=50.4, Expect=2e-06]} {Celegans: WBGene00018798, gnrr-1, GoNadotropin-Releasing hormone Receptor (GnRHR) related, [Score=48.9, Expect=3e-06]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=160, Expect=9e-47]} {RNA1310_30553}

Mlig455_063749 {REF} {Length: 1323} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.3]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.4]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=157, Expect=1e-45]} {RNA1310_30553}
42. MligTC455_34524 155 3.22 Mlig455_021291

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.905

Region-enriched R2: 4.200/0.01842

4.571 0.911 0.878 0.838 - 0.966 0.978 Mlig455_021291 {REF} {Length: 1478} {NoTransDecoderORF} {RNA1509_56543} {RNA1310_26920, RNA1509_56543} {RNA1509_56543, RNA815_11718}
43. MligTC455_43581 177 3.68 Mlig455_042725, Mlig455_042827, Mlig455_063146

Neo: -

Age: Up-Down-Down

GRIA2 4.564 0.833 - 0.972 0.967 0.825 0.967

Mlig455_042725 {REF} {Length: 3074} {Pfam: Ligand-gated ion channel [PF00060.28, score=104.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.7]; Receptor family ligand binding region [PF01094.30, score=33.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=153, Expect=1e-37]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=149, Expect=2e-36]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=147, Expect=7e-36]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=152, Expect=2e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=148, Expect=3e-36]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=147, Expect=8e-36]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=2e-35]} {Dmel: FBgn0038837, CG3822, [Score=140, Expect=5e-34]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=253, Expect=2e-76]} {RNA1310_25150} {RNA815_13942}

Mlig455_042827 {REF} {Length: 2869} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.9]; Receptor family ligand binding region [PF01094.30, score=49.8]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.3]; Iron-containing alcohol dehydrogenase [PF13685.8, score=18.6]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=125, Expect=6e-29]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=122, Expect=5e-28]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=121, Expect=7e-28]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=120, Expect=2e-27]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=125, Expect=5e-29]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=122, Expect=4e-28]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=121, Expect=1e-27]; ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=120, Expect=1e-27]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=119, Expect=3e-27]} {Dmel: FBgn0039927, CG11155, [Score=127, Expect=7e-30]} {Celegans: WBGene00001612, glr-1, Glutamate receptor 1, [Score=103, Expect=1e-22]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=217, Expect=2e-63]} {RNA1310_25150} {RNA815_13942}

Mlig455_063146 {REF} {Length: 2444} {Pfam: Receptor family ligand binding region [PF01094.30, score=35.8]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=82.4, Expect=1e-16]} {RNA1310_25150} {RNA815_13999}
44. MligTC455_29408 45 0.94 Mlig455_038322

Neo: -

Age: -

Region-enriched R2: 8.586/0.00762

MB 4.554 0.908 0.797 - 0.948 0.907 0.994 Mlig455_038322 {REF} {Length: 2059} {Pfam: Globin [PF00042.24, score=57.8]} {Human: ENSG00000198125, MB, myoglobin, [RH, Score=47.8, Expect=5e-07]} {Mouse: ENSMUSG00000018893, Mb, myoglobin, [RH, Score=45.4, Expect=2e-06]} {Celegans: WBGene00008996, glb-14, GLoBin related, [Score=51.6, Expect=4e-08]} {Smed: dd_Smed_v6_15997_0_1, dd_Smed_v6_15997_0_1, [RH, Score=63.5, Expect=1e-12]} {RNA1509_48898} {RNA1310_47695} {RNA815_7096.1}
45. MligTC455_46880 44 0.91 Mlig455_046271

Neo: -

Age: -

IAH1 4.55 0.856 - 0.875 0.968 0.864 0.987 Mlig455_046271 {REF} {Length: 1061} {Pfam: GDSL-like Lipase/Acylhydrolase family [PF13472.8, score=75.8]; GDSL-like Lipase/Acylhydrolase [PF00657.24, score=32.0]} {Human: ENSG00000134330, IAH1, isoamyl acetate hydrolyzing esterase 1 (putative), [Score=138, Expect=2e-39]} {Mouse: ENSMUSG00000062054, Iah1, isoamyl acetate-hydrolyzing esterase 1 homolog, [Score=121, Expect=4e-33]} {Smed: dd_Smed_v6_6241_0_1, dd_Smed_v6_6241_0_1, [Score=111, Expect=8e-30]} {RNA1310_130726}
46. MligTC455_26255 126 2.63 Mlig455_053706

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.424/0.00107
Region-enriched R4: 3.360/0.04239

FZD5 4.529 0.760 - 0.952 0.948 0.871 0.998 Mlig455_053706 {REF} {Length: 3671} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=393.1]; Fz domain [PF01392.24, score=105.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [RH, Score=607, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=600, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [RH, Score=562, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [RH, Score=412, Expect=5e-137]} {Smed: dd_Smed_v6_11823_0_1, dd_Smed_v6_11823_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_49831} {RNA1310_28187, RNA1509_49831} {RNA1509_49831, RNA815_16996}
47. MligTC455_46430 62 1.29 Mlig455_057117, Mlig455_069301

Neo: -

Age: -

GUCY2F 4.526 0.948 0.879 0.861 - 0.841 0.997

Mlig455_057117 {REF} {Length: 2651} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=196.0]; Nitrate and nitrite sensing [PF08376.12, score=82.5]; Heme NO binding associated [PF07701.16, score=28.2]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=247, Expect=9e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=242, Expect=3e-68]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=238, Expect=5e-67]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=246, Expect=7e-70]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=242, Expect=2e-68]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=241, Expect=7e-68]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=239, Expect=3e-67]} {Dmel: FBgn0053958, CG33958, [Score=266, Expect=4e-79]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=235, Expect=3e-66]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=238, Expect=4e-67]} {RNA1509_38781} {RNA1310_35456} {RNA815_22108}

Mlig455_069301 {REF} {Length: 2370} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=178.1]; Nitrate and nitrite sensing [PF08376.12, score=82.3]; Heme NO binding associated [PF07701.16, score=28.0]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=232, Expect=2e-64]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=232, Expect=1e-64]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=225, Expect=5e-62]} {Dmel: FBgn0053958, CG33958, [Score=250, Expect=5e-73]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=223, Expect=1e-61]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=221, Expect=4e-61]} {RNA1509_38781} {RNA1310_35456} {RNA815_24181}
48. MligTC455_47080 362 7.54 Mlig455_037356

Neo: -

Age: -

Region-enriched R2: 2.691/0.00566

SSUH2 4.523 0.911 0.789 - 0.856 0.977 0.990 Mlig455_037356 {REF} {Length: 1984} {Pfam: DnaJ central domain [PF00684.21, score=20.9]} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=189, Expect=3e-56]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=156, Expect=5e-44]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=90.9, Expect=7e-20]} {RNA1509_29510} {RNA1310_15488, RNA1509_29510} {RNA1509_29510, RNA815_5650}
49. MligTC455_40657 90 1.87 Mlig455_040779

Neo: -

Age: -

CLIP2 4.521 0.937 0.933 0.726 0.928 0.997 - Mlig455_040779 {REF} {Length: 2164} {Pfam: CAP-Gly domain [PF01302.27, score=60.7]} {Human: ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000063146, Clip2, CAP-GLY domain containing linker protein 2, [Score=62.0, Expect=1e-09]} {Dmel: FBgn0036882, CG9279, [Score=54.7, Expect=1e-07]} {Smed: dd_Smed_v6_12985_0_1, dd_Smed_v6_12985_0_1, [Score=56.2, Expect=2e-08]} {RNA1310_20676} {RNA815_40746}
50. MligTC455_29045 127 2.65 Mlig455_056054

Neo: -

Age: -

Region-enriched R2: 4.858/0.00652

FZD5 4.513 0.895 0.915 0.758 0.948 - 0.997 Mlig455_056054 {REF} {Length: 3655} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=389.0]; Fz domain [PF01392.24, score=85.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=554, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [Score=561, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=516, Expect=5e-176]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=368, Expect=3e-120]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [Score=522, Expect=7e-178]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
51. MligTC455_32359 194 4.04 Mlig455_054395, Mlig455_054418, Mlig455_070496

Neo: -

Age: -

Region-enriched R2: 3.120/0.02401

STON2 4.513 0.953 0.922 0.815 - 0.979 0.844

Mlig455_054395 {REF} {Length: 3807} {Pfam: Adaptor complexes medium subunit family [PF00928.23, score=152.1]} {Human: ENSG00000140022, STON2, stonin 2, [RH, Score=281, Expect=5e-80]} {Mouse: ENSMUSG00000020961, Ston2, stonin 2, [RH, Score=285, Expect=3e-82]} {Dmel: FBgn0016975, stnB, stoned B, [RH, Score=374, Expect=3e-112]} {Celegans: WBGene00006777, unc-41, Putative stoned B-like protein, [RH, Score=356, Expect=3e-104]} {Smed: dd_Smed_v6_6859_0_1, dd_Smed_v6_6859_0_1, [RH, Score=684, Expect=0.0]} {RNA1509_39423} {RNA1310_6760} {RNA815_11749}

Mlig455_054418 {REF} {Length: 3915} {Pfam: Adaptor complexes medium subunit family [PF00928.23, score=153.1]} {Human: ENSG00000140022, STON2, stonin 2, [RH, Score=281, Expect=3e-80]} {Mouse: ENSMUSG00000020961, Ston2, stonin 2, [RH, Score=284, Expect=5e-82]} {Dmel: FBgn0016975, stnB, stoned B, [RH, Score=374, Expect=4e-112]} {Celegans: WBGene00006777, unc-41, Putative stoned B-like protein, [RH, Score=355, Expect=4e-104]} {Smed: dd_Smed_v6_6859_0_1, dd_Smed_v6_6859_0_1, [RH, Score=686, Expect=0.0]} {RNA1509_39423} {RNA1310_6760, RNA1509_39423} {RNA1509_39423, RNA815_11749}

Mlig455_070496 {REF} {Length: 3566} {Pfam: Adaptor complexes medium subunit family [PF00928.23, score=76.5]} {Human: ENSG00000140022, STON2, stonin 2, [Score=178, Expect=9e-46]} {Mouse: ENSMUSG00000020961, Ston2, stonin 2, [Score=182, Expect=2e-47]} {Dmel: FBgn0016975, stnB, stoned B, [Score=250, Expect=7e-70]} {Celegans: WBGene00006777, unc-41, Putative stoned B-like protein, [Score=235, Expect=1e-64]} {Smed: dd_Smed_v6_6859_0_2, dd_Smed_v6_6859_0_2, [Score=467, Expect=5e-152]} {RNA1509_39423} {RNA1310_6760} {RNA815_11749}
52. MligTC455_42994 1521 31.7 Mlig455_035840

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.356

Region-enriched R2: 1.854/0.00052

4.513 - 0.823 0.874 0.895 0.944 0.977 Mlig455_035840 {REF} {Length: 1436} {RNA1509_29485, RNA1509_42231} {RNA1310_26640, RNA1509_29485, RNA1509_42231} {RNA1509_29485, RNA1509_42231, RNA815_37260}
53. MligTC455_45350 92 1.93 Mlig455_024760, Mlig455_058317, Mlig455_068656

Neo: -

Age: Up-Down-Down

SLC17A6, SLC17A8 4.505 0.894 0.847 0.848 - 0.925 0.991

Mlig455_024760 {REF} {Length: 2935} {Pfam: Major Facilitator Superfamily [PF07690.18, score=158.2]} {Human: ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=522, Expect=5e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=530, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=527, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=487, Expect=1e-165]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=474, Expect=3e-161]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=583, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}

Mlig455_058317 {REF} {Length: 2971} {Pfam: Major Facilitator Superfamily [PF07690.18, score=157.7]} {Human: ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=534, Expect=0.0]; ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=521, Expect=8e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=531, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=526, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=485, Expect=1e-164]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [Score=474, Expect=7e-162]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [Score=585, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}

Mlig455_068656 {REF} {Length: 3034} {Pfam: Major Facilitator Superfamily [PF07690.18, score=158.2]} {Human: ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=522, Expect=5e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=530, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=527, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=487, Expect=1e-165]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=474, Expect=3e-161]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=583, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}
54. MligTC455_43963 1010 21.04 Mlig455_015437

Neo: -

Age: Down-Down-Up

Region-enriched R2: 2.083/0.01168

4.498 0.788 - 0.951 0.852 0.934 0.973 Mlig455_015437 {REF} {Length: 612} {RNA1509_32160} {RNA1310_60746, RNA1509_32160} {RNA1509_32160, RNA815_30740}
55. MligTC455_40852 128 2.66 Mlig455_042301

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.671

Region-enriched R2: 6.158/0.00357

PKDREJ 4.494 0.970 - 0.954 0.850 0.748 0.972 Mlig455_042301 {REF} {Length: 11184} {Pfam: Polycystin cation channel [PF08016.14, score=273.5]; PKD domain [PF00801.22, score=86.2]; PLAT/LH2 domain [PF01477.25, score=67.1]; REJ domain [PF02010.17, score=66.8]; PKD domain [PF18911.2, score=62.3]; Ion transport protein [PF00520.33, score=45.4]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=283, Expect=2e-75]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=273, Expect=2e-72]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=158, Expect=3e-38]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=254, Expect=4e-67]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=514, Expect=2e-146]} {RNA1509_8046} {RNA1310_93, RNA1509_8046} {RNA1509_8046, RNA815_1216}
56. MligTC455_44646 193 4.01 Mlig455_013515

Neo: -

Age: Down-Up-Down

SCNN1B 4.488 0.843 - 0.944 0.950 0.801 0.950 Mlig455_013515 {REF} {Length: 2272} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=308.7]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [RH, Score=191, Expect=3e-52]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [RH, Score=188, Expect=3e-51]} {Dmel: FBgn0030795, ppk28, pickpocket 28, [Score=68.2, Expect=1e-11]} {Celegans: WBGene00012137, asic-2, Degenerin-like protein asic-2, [Score=143, Expect=2e-36]} {Smed: dd_Smed_v6_17021_0_1, dd_Smed_v6_17021_0_1, [Score=175, Expect=2e-47]} {RNA1509_52917} {RNA1310_12013.1, RNA1509_52917} {RNA1509_52917, RNA815_4777}
57. MligTC455_14716 29 0.61 Mlig455_043633

Neo: -

Age: -

ANGPTL2 4.481 - 0.738 0.955 0.814 0.988 0.986 Mlig455_043633 {REF} {Length: 1106} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=157.6]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=134, Expect=2e-35]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=133, Expect=4e-35]; ENSG00000085265, FCN1, ficolin 1, [Score=132, Expect=8e-36]; ENSG00000160339, FCN2, ficolin 2, [Score=128, Expect=4e-35]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=137, Expect=1e-36]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=134, Expect=1e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=131, Expect=1e-34]} {Dmel: FBgn0034160, CG5550, [Score=119, Expect=6e-32]} {Celegans: WBGene00017013, ensh-1, [Score=57.8, Expect=2e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=114, Expect=1e-28]} {RNA1509_26827} {RNA1310_31596.2} {RNA815_17173.3}
58. MligTC455_21755 70 1.47 Mlig455_021213

Neo: -

Age: -

4.475 0.965 0.793 0.748 0.971 - 0.998 Mlig455_021213 {REF} {Length: 4215} {Pfam: F5/8 type C domain [PF00754.27, score=55.5]} {RNA1509_2515} {RNA1310_33166} {RNA815_14716}
59. MligTC455_42037 1931 40.23 Mlig455_063391

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.444

Region-specific R2: 2.479

Region-enriched R2: 1.442/0.00136

4.473 - 0.719 0.860 0.957 0.984 0.953 Mlig455_063391 {REF} {Length: 1482} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1310_24553, RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236, RNA815_11766}
60. MligTC455_39222 213 4.44 Mlig455_064653, Mlig455_064686

Neo: -

Age: -

Region-enriched R2: 4.317/0.00597

4.471 0.846 0.804 0.945 - 0.897 0.979

Mlig455_064653 {REF} {Length: 2836} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.9, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=7e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_56255} {RNA1310_13407} {RNA815_38407}

Mlig455_064686 {REF} {Length: 3820} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.5, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=8e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_50956} {RNA1310_13407} {RNA815_38407}
61. MligTC455_48022 1337 27.86 Mlig455_045267, Mlig455_069186

Neo: -

Age: -

Region-enriched R2: 2.130/0.00146

4.47 - 0.746 0.908 0.951 0.980 0.885

Mlig455_045267 {REF} {Length: 3628} {Pfam: Ankyrin repeats (many copies) [PF13857.8, score=29.5]; Ankyrin repeats (many copies) [PF13637.8, score=28.4]; Ankyrin repeats (3 copies) [PF12796.9, score=28.3]; Ankyrin repeat [PF13606.8, score=23.5]} {Celegans: WBGene00009375, F34D10.6, [Score=57.0, Expect=6e-08]} {Smed: dd_Smed_v6_5594_0_3, dd_Smed_v6_5594_0_3, [Score=58.5, Expect=1e-08]} {RNA1509_17412, RNA1509_32079} {RNA1310_5952, RNA1509_17412, RNA1509_32079} {RNA1509_17412, RNA1509_32079, RNA815_2323}

Mlig455_069186 {REF} {Length: 3598} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=30.4]; Ankyrin repeats (3 copies) [PF12796.9, score=30.1]; Ankyrin repeats (many copies) [PF13857.8, score=29.5]; Ankyrin repeat [PF13606.8, score=24.1]} {Celegans: WBGene00009375, F34D10.6, [Score=56.6, Expect=6e-08]} {Smed: dd_Smed_v6_5594_0_4, dd_Smed_v6_5594_0_4, [Score=59.3, Expect=7e-09]} {RNA1509_52963} {RNA1310_5952, RNA1509_52963} {RNA1509_52963, RNA815_2323}
62. MligTC455_14715 31 0.65 Mlig455_043609

Neo: -

Age: -

ANGPTL1 4.465 - 0.738 0.953 0.803 0.985 0.986 Mlig455_043609 {REF} {Length: 1252} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=154.2]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=131, Expect=2e-34]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=128, Expect=2e-33]; ENSG00000085265, FCN1, ficolin 1, [Score=128, Expect=2e-34]; ENSG00000160339, FCN2, ficolin 2, [Score=125, Expect=5e-34]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=134, Expect=1e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=129, Expect=7e-34]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=128, Expect=2e-33]} {Dmel: FBgn0033312, CG8642, [RH, Score=122, Expect=1e-31]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=112, Expect=7e-28]} {RNA1509_26827} {RNA1310_31596.2} {RNA815_17173.3}
63. MligTC455_18506 59 1.23 Mlig455_038054

Neo: -

Age: Down-Up-Down

SP9 4.464 - 0.798 0.887 0.973 0.812 0.994 Mlig455_038054 {REF} {Length: 3168} {Pfam: Zinc-finger double domain [PF13465.8, score=49.0]; Zinc finger, C2H2 type [PF00096.28, score=40.9]; C2H2-type zinc finger [PF13894.8, score=26.8]} {Human: ENSG00000217236, SP9, Sp9 transcription factor, [RH, Score=202, Expect=4e-59]; ENSG00000164651, SP8, Sp8 transcription factor, [RH, Score=202, Expect=5e-59]} {Mouse: ENSMUSG00000068859, Sp9, trans-acting transcription factor 9, [RH, Score=202, Expect=3e-59]; ENSMUSG00000048562, Sp8, trans-acting transcription factor 8, [RH, Score=201, Expect=9e-59]} {Dmel: FBgn0020378, Sp1, [RH, Score=198, Expect=6e-56]} {Celegans: WBGene00012735, sptf-3, SP (Specificity Protein) Transcription Factor, [Score=137, Expect=1e-35]} {Smed: dd_Smed_v6_17385_0_1, dd_Smed_v6_17385_0_1, [RH, Score=160, Expect=5e-46]} {RNA1310_42373}
64. MligTC455_04786 26 0.55 Mlig455_043817, Mlig455_047431

Neo: -

Age: -

4.461 0.856 - 0.954 0.955 0.702 0.994

Mlig455_043817 {REF} {Length: 319} {NoTransDecoderORF} {RNA1310_64690}

Mlig455_047431 {REF} {Length: 2194} {Pfam: Glycine rich protein [PF12810.9, score=25.3]} {RNA1509_16377} {RNA1310_33363.2} {RNA815_25152}
65. MligTC455_18099 24 0.51 Mlig455_036525

Neo: -

Age: -

PPA1 4.459 0.856 - 0.947 0.790 0.877 0.989 Mlig455_036525 {REF} {Length: 1911} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1310_57333.1} {RNA815_22340}
66. MligTC455_29915 50 1.04 Mlig455_027934

Neo: -

Age: Down-Up-Up

Region-enriched R2: 6.881/0.04464

ANGPTL1 4.452 0.958 - 0.822 0.920 0.764 0.988 Mlig455_027934 {REF} {Length: 2265} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=43.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=48.9, Expect=9e-06]} {Dmel: FBgn0031804, CG9500, [Score=53.1, Expect=9e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=49.7, Expect=1e-06]} {RNA1509_53291} {RNA1310_38229.1} {RNA815_10579.1}
67. MligTC455_19042 3679 76.64 Mlig455_030661

Neo: -

Age: logFC(26M/2M)=0.480

Region-specific R2: 2.811

Region-enriched R2: 1.755/0.00003

CAV1 4.451 0.731 - 0.938 0.985 0.857 0.940 Mlig455_030661 {REF} {Length: 1257} {Pfam: Caveolin [PF01146.19, score=124.8]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=105, Expect=2e-29]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=105, Expect=2e-29]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=81.6, Expect=8e-20]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=144, Expect=1e-45]} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1310_31540, RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522, RNA815_14585}
68. MligTC455_40352 49 1.03 Mlig455_024410

Neo: -

Age: -

4.447 0.952 - 0.872 0.906 0.769 0.948 Mlig455_024410 {REF} {Length: 1509} {TRANSSPLICED} {RNA1310_29008} {RNA815_41596}
69. MligTC455_23621 323 6.72 Mlig455_039694, Mlig455_039749

Neo: -

Age: -

Region-enriched R2: 2.235/0.02499

4.446 0.825 - 0.831 0.963 0.833 0.994

Mlig455_039694 {REF} {Length: 2054} {RNA1509_29694} {RNA1310_14789} {RNA815_12997}

Mlig455_039749 {REF} {Length: 1751} {RNA1509_29694} {RNA1310_14789, RNA1509_29694} {RNA1509_29694, RNA815_12997}
70. MligTC455_09697 52 1.08 Mlig455_009478, Mlig455_061921

Neo: -

Age: -

CD207 4.441 0.834 - 0.957 0.885 0.771 0.994

Mlig455_009478 {REF} {Length: 1068} {Pfam: Lectin C-type domain [PF00059.23, score=39.5]} {Human: ENSG00000116031, CD207, CD207 molecule, [Score=48.5, Expect=5e-06]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=1e-13]} {RNA1310_33496.1} {RNA815_23317}

Mlig455_061921 {REF} {Length: 776} {Pfam: Lectin C-type domain [PF00059.23, score=35.3]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=69.7, Expect=4e-14]} {RNA1310_33496.1} {RNA815_23317}
71. MligTC455_41028 108 2.26 Mlig455_033278

Neo: -

Age: -

4.441 0.862 0.884 0.775 0.935 - 0.985 Mlig455_033278 {REF} {Length: 1134} {Pfam: PAN domain [PF00024.28, score=19.4]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=9e-14]} {RNA1310_31986} {RNA815_17816.2}
72. MligTC455_16874 38 0.8 Mlig455_028170

Neo: -

Age: -

KCNK18 4.434 0.953 - 0.740 0.930 0.812 0.999 Mlig455_028170 {REF} {Length: 2452} {Pfam: Ion channel [PF07885.18, score=103.1]; Protein of unknown function (DUF3112) [PF11309.10, score=20.2]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [Score=96.7, Expect=1e-21]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=2e-23]} {Dmel: FBgn0033257, sand, sandman, [Score=129, Expect=2e-33]} {Celegans: WBGene00006680, twk-28, TWiK family of potassium channels, [Score=144, Expect=3e-38]} {Smed: dd_Smed_v6_17586_0_1, dd_Smed_v6_17586_0_1, [Score=270, Expect=2e-87]} {RNA1509_39975} {RNA1310_18301.1} {RNA815_12440}
73. MligTC455_35895 102 2.12 Mlig455_063971

Neo: -

Age: -

RYK 4.434 0.897 - 0.757 0.917 0.899 0.964 Mlig455_063971 {REF} {Length: 3496} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=209.4]; WIF domain [PF02019.20, score=109.7]; Protein kinase domain [PF00069.27, score=79.1]} {Human: ENSG00000163785, RYK, receptor-like tyrosine kinase, [Score=202, Expect=1e-55]} {Mouse: ENSMUSG00000032547, Ryk, receptor-like tyrosine kinase, [RH, Score=202, Expect=2e-55]} {Dmel: FBgn0015380, drl, derailed, [RH, Score=239, Expect=4e-69]} {Celegans: WBGene00003007, lin-18, Inactive tyrosine-protein kinase RYK, [Score=179, Expect=6e-48]} {Smed: dd_Smed_v6_12594_0_2, dd_Smed_v6_12594_0_2, [Score=201, Expect=3e-55]} {RNA1509_58811} {RNA1310_6671.2} {RNA815_41921}
74. MligTC455_46394 8810 183.54 Mlig455_054818, Mlig455_054826

Neo: -

Age: -

Region-specific R2: 1.771

Region-enriched R2: 1.255/0.00038

PKD2 4.432 - 0.724 0.796 0.953 0.978 0.981

Mlig455_054818 {REF} {Length: 2992} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=747, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=380, Expect=6e-120]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [Score=733, Expect=0.0]} {RNA1509_1615} {RNA1310_21296.2, RNA1509_1615} {RNA1509_1615, RNA815_3158.1}

Mlig455_054826 {REF} {Length: 3118} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.4]; EF hand [PF00036.34, score=32.6]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=754, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=751, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=2e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=1e-122]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
75. MligTC455_27692 1230 25.62 Mlig455_041598

Neo: -

Age: logFC(26M/2M)=-0.459

Region-enriched R7: 1.679/0.00325
Region-enriched R8: 1.607/0.03580
Region-enriched R2: 1.508/0.02284

TUBA1A 4.425 - 0.749 0.788 0.933 0.985 0.970 Mlig455_041598 {REF} {Length: 2325} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=229.7]; Tubulin C-terminal domain [PF03953.19, score=175.5]; Tubulin domain [PF14881.8, score=18.9]} {Human: ENSG00000167552, TUBA1A, tubulin alpha 1a, [RH, Score=926, Expect=0.0]; ENSG00000123416, TUBA1B, tubulin alpha 1b, [RH, Score=923, Expect=0.0]; ENSG00000167553, TUBA1C, tubulin alpha 1c, [RH, Score=887, Expect=0.0]} {Mouse: ENSMUSG00000072235, Tuba1a, tubulin, alpha 1A, [RH, Score=926, Expect=0.0]; ENSMUSG00000023004, Tuba1b, tubulin, alpha 1B, [RH, Score=923, Expect=0.0]} {Dmel: FBgn0003884, alphaTub84B, alpha-Tubulin at 84B, [RH, Score=917, Expect=0.0]} {Celegans: WBGene00003175, mec-12, Tubulin alpha-3 chain Detyrosinated tubulin alpha-3 chain, [RH, Score=850, Expect=0.0]} {Smed: dd_Smed_v6_38_0_1, dd_Smed_v6_38_0_1, [RH, Score=924, Expect=0.0]} {RNA1509_21352, RNA1509_42319, RNA1509_9718} {RNA1310_10339.1, RNA1509_21352, RNA1509_42319} {RNA1509_21352, RNA1509_42319, RNA815_1715.1}
76. MligTC455_28724 128 2.66 Mlig455_017717

Neo: -

Age: Up-Down-Down

ANK1 4.423 0.950 0.909 0.832 0.904 - 0.828 Mlig455_017717 {REF} {Length: 9852} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=513.3]; Ankyrin repeats (many copies) [PF13637.8, score=459.4]; Ankyrin repeats (many copies) [PF13857.8, score=371.3]; Ankyrin repeat [PF13606.8, score=296.0]; Ankyrin repeat [PF00023.32, score=166.1]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=149, Expect=4e-35]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=143, Expect=2e-33]} {Mouse: ENSMUSG00000014498, Ankrd52, ankyrin repeat domain 52, [Score=145, Expect=3e-34]; ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=142, Expect=3e-33]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=142, Expect=3e-33]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=147, Expect=9e-35]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=129, Expect=1e-29]} {Smed: dd_Smed_v6_5303_0_2, dd_Smed_v6_5303_0_2, [Score=171, Expect=7e-43]} {RNA1509_11517} {RNA1310_203} {RNA815_6981}
77. MligTC455_39988 83 1.73 Mlig455_062081

Neo: -

Age: -

4.417 0.934 - 0.899 0.859 0.727 0.998 Mlig455_062081 {REF} {Length: 447} {NoTransDecoderORF} {RNA1509_50426} {RNA1310_88257} {RNA815_17173.4}
78. MligTC455_45051 307 6.41 Mlig455_043687, Mlig455_043755

Neo: -

Age: -

4.417 - 0.761 0.954 0.857 0.975 0.870

Mlig455_043687 {REF} {Length: 1460} {RNA1310_17293.1}

Mlig455_043755 {REF} {Length: 1366} {TRANSSPLICED} {RNA1310_17293.1}
79. MligTC455_53682 393 8.18 Mlig455_064952, Mlig455_066834

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.926

Region-enriched R2: 4.442/0.00896

4.41 - 0.727 0.887 0.970 0.856 0.970

Mlig455_064952 {REF} {Length: 1573} {Pfam: PAN domain [PF00024.28, score=20.0]} {RNA1310_33258} {RNA815_17150}

Mlig455_066834 {REF} {Length: 1573} {Pfam: PAN domain [PF00024.28, score=20.0]} {RNA1310_33258} {RNA815_17150}
80. MligTC455_15949 37 0.76 Mlig455_059880

Neo: -

Age: -

4.402 0.934 - 0.964 0.805 0.723 0.976 Mlig455_059880 {REF} {Length: 1226} {Pfam: Lectin C-type domain [PF00059.23, score=39.5]} {Dmel: FBgn0031373, CG15358, [Score=52.8, Expect=4e-08]} {RNA1310_120903}
81. MligTC455_51199 206 4.29 Mlig455_044015

Neo: -

Age: Down-Up-Down

ARX 4.4 0.830 - 0.937 0.956 0.961 0.716 Mlig455_044015 {REF} {Length: 1926} {Pfam: Homeodomain [PF00046.31, score=85.3]} {Human: ENSG00000004848, ARX, aristaless related homeobox, [Score=116, Expect=8e-30]} {Mouse: ENSMUSG00000035277, Arx, aristaless related homeobox, [Score=115, Expect=1e-29]} {Dmel: FBgn0008636, hbn, homeobrain, [Score=128, Expect=5e-35]} {Celegans: WBGene00000433, ceh-8, Homeobox protein ceh-8, [RH, Score=103, Expect=6e-27]} {Smed: dd_Smed_v6_16955_0_1, dd_Smed_v6_16955_0_1, [Score=105, Expect=9e-27]} {RNA1509_46102} {RNA1310_37906, RNA1509_46102}
82. MligTC455_46708 362 7.53 Mlig455_045334

Neo: -

Age: -

Region-enriched R2: 2.783/0.01800

4.395 - 0.734 0.936 0.957 0.811 0.957 Mlig455_045334 {REF} {Length: 1243} {RNA1509_51601} {RNA1310_43115.2, RNA1509_51601} {RNA1509_51601, RNA815_21402.1}
83. MligTC455_19277 1013 21.11 Mlig455_059600

Neo: -

Age: -

Region-specific R2: 4.883

Region-enriched R2: 5.766/0.00000
Region-enriched R3: 2.030/0.00976

4.383 - 0.819 0.864 0.815 0.931 0.954 Mlig455_059600 {REF} {Length: 827} {NoTransDecoderORF} {RNA1509_43907} {RNA1310_81348}
84. MligTC455_47875 72 1.5 Mlig455_067941

Neo: -

Age: -

4.377 0.768 - 0.947 0.980 0.916 0.766 Mlig455_067941 {REF} {Length: 1399} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.8, Expect=7e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
85. MligTC455_47538 50 1.03 Mlig455_025826

Neo: -

Age: -

Region-enriched R2: 5.073/0.01138
Region-enriched R3: 3.811/0.02847

CALM2 4.374 0.922 0.789 - 0.957 0.825 0.881 Mlig455_025826 {REF} {Length: 1670} {Pfam: EF hand [PF00036.34, score=107.9]; EF-hand domain pair [PF13499.8, score=105.5]; EF hand [PF13202.8, score=83.6]; EF-hand domain pair [PF13833.8, score=83.3]; EF-hand domain [PF13405.8, score=75.8]; EF-hand domain [PF14658.8, score=35.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=29.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.8]; Dockerin type I domain [PF00404.20, score=20.3]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=93.2, Expect=3e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=93.2, Expect=3e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=93.2, Expect=3e-24]; ENSG00000178363, CALML3, calmodulin like 3, [Score=92.8, Expect=4e-24]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=99.8, Expect=5e-27]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=91.3, Expect=6e-24]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=90.9, Expect=9e-24]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=90.9, Expect=7e-24]} {RNA1509_52504} {RNA1310_7529} {RNA815_34450}
86. MligTC455_49957 119 2.47 Mlig455_005610, Mlig455_014448

Neo: -

Age: -

4.371 0.831 0.814 - 0.738 0.992 0.996

Mlig455_005610 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=66.2, Expect=4e-13]} {RNA1310_45206} {RNA815_28788}

Mlig455_014448 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=63.2, Expect=6e-12]} {RNA1310_45206} {RNA815_28788}
87. MligTC455_13927 79 1.65 Mlig455_025242, Mlig455_025623

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.383

KIF1B 4.368 0.775 0.889 - 0.762 0.949 0.993

Mlig455_025242 {REF} {Length: 3364} {Pfam: FHA domain [PF00498.28, score=31.2]; Kinesin protein 1B [PF12423.10, score=29.5]} {Human: ENSG00000054523, KIF1B, kinesin family member 1B, [Score=52.4, Expect=2e-06]; ENSG00000197892, KIF13B, kinesin family member 13B, [Score=51.6, Expect=4e-06]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [Score=160, Expect=5e-41]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=58.2, Expect=2e-08]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [Score=210, Expect=2e-58]} {Smed: dd_Smed_v6_20223_0_1, dd_Smed_v6_20223_0_1, [Score=348, Expect=3e-110]} {RNA1310_9866} {RNA815_27415}

Mlig455_025623 {REF} {Length: 4205} {Pfam: Kinesin motor domain [PF00225.25, score=345.1]; Microtubule binding [PF16796.7, score=70.6]; FHA domain [PF00498.28, score=30.2]; Kinesin-associated [PF16183.7, score=29.6]; Kinesin protein 1B [PF12423.10, score=28.9]} {Human: ENSG00000054523, KIF1B, kinesin family member 1B, [Score=464, Expect=6e-145]; ENSG00000130294, KIF1A, kinesin family member 1A, [Score=450, Expect=1e-135]; ENSG00000129250, KIF1C, kinesin family member 1C, [Score=448, Expect=2e-139]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [RH, Score=598, Expect=0.0]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=441, Expect=6e-132]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [Score=703, Expect=0.0]} {Smed: dd_Smed_v6_12573_0_1, dd_Smed_v6_12573_0_1, [Score=806, Expect=0.0]} {RNA1509_18998} {RNA1310_9866} {RNA815_31497}
88. MligTC455_14904 4225 88.01 Mlig455_037596

Neo: -

Age: logFC(26M/2M)=0.385

Region-enriched R8: 1.541/0.00053

4.367 - 0.713 0.899 0.992 0.801 0.962 Mlig455_037596 {REF} {Length: 2914} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=59.3, Expect=3e-09]} {RNA1509_17730, RNA1509_4337} {RNA1310_7259, RNA1509_17730} {RNA1509_17730, RNA815_206}
89. MligTC455_12512 80 1.68 Mlig455_017689

Neo: -

Age: -

4.362 0.856 - 0.973 0.819 0.719 0.995 Mlig455_017689 {REF} {Length: 934} {RNA1310_37507} {RNA815_32171}
90. MligTC455_53843 1448 30.17 Mlig455_048664

Neo: -

Age: logFC(26M/2M)=0.488

4.355 0.752 - 0.770 0.907 0.967 0.959 Mlig455_048664 {REF} {Length: 1660} {RNA1509_15580} {RNA1310_24090, RNA1509_15580} {RNA1509_15580, RNA815_10676.2}
91. MligTC455_19328 99 2.06 Mlig455_062531

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.972/0.00232

4.35 0.964 0.957 0.881 - 0.735 0.813 Mlig455_062531 {REF} {Length: 1929} {NoTransDecoderORF} {RNA1509_36058} {RNA1310_3092} {RNA815_16673}
92. MligTC455_25242 55 1.15 Mlig455_046799, Mlig455_063518

Neo: -

Age: -

Region-enriched R2: 5.810/0.00185

DOC2B, RPH3A 4.345 - 0.763 0.951 0.921 0.746 0.964

Mlig455_046799 {REF} {Length: 1832} {Pfam: C2 domain [PF00168.32, score=147.1]} {Human: ENSG00000272636, DOC2B, double C2 domain beta, [Score=243, Expect=3e-76]; ENSG00000272670, DOC2B, double C2 domain beta, [Score=243, Expect=3e-76]; ENSG00000089169, RPH3A, rabphilin 3A, [Score=237, Expect=3e-71]; ENSG00000149927, DOC2A, double C2 domain alpha, [Score=234, Expect=1e-72]} {Mouse: ENSMUSG00000020848, Doc2b, double C2, beta, [Score=243, Expect=3e-76]; ENSMUSG00000052301, Doc2a, double C2, alpha, [Score=239, Expect=1e-74]; ENSMUSG00000029608, Rph3a, rabphilin 3A, [Score=237, Expect=4e-71]} {Dmel: FBgn0030230, Rph, Rabphilin, [RH, Score=188, Expect=2e-55]} {Celegans: WBGene00004316, rbf-1, Rabphilin-1, [Score=216, Expect=4e-62]} {Smed: dd_Smed_v6_12977_0_1, dd_Smed_v6_12977_0_1, [Score=239, Expect=5e-73]} {RNA1310_26201} {RNA815_12702}

Mlig455_063518 {REF} {Length: 2724} {Pfam: C2 domain [PF00168.32, score=147.7]} {Human: ENSG00000089169, RPH3A, rabphilin 3A, [RH, Score=240, Expect=2e-72]} {Mouse: ENSMUSG00000029608, Rph3a, rabphilin 3A, [RH, Score=240, Expect=2e-72]} {Dmel: FBgn0030230, Rph, Rabphilin, [RH, Score=191, Expect=1e-54]} {Celegans: WBGene00004316, rbf-1, Rabphilin-1, [Score=219, Expect=4e-63]} {Smed: dd_Smed_v6_12977_0_2, dd_Smed_v6_12977_0_2, [Score=241, Expect=1e-73]} {RNA1310_26201} {RNA815_12702}
93. MligTC455_36618 545 11.35 Mlig455_020301, Mlig455_020358

Neo: -

Age: logFC(26M/2M)=-0.435

Region-enriched R2: 3.072/0.00097

SLC7A6 4.334 0.931 0.774 0.740 0.974 0.915 -

Mlig455_020301 {REF} {Length: 4137} {Pfam: Amino acid permease [PF13520.8, score=183.8]; Amino acid permease [PF00324.23, score=95.7]} {Human: ENSG00000103064, SLC7A6, solute carrier family 7 member 6, [RH, Score=421, Expect=7e-143]; ENSG00000155465, SLC7A7, solute carrier family 7 member 7, [RH, Score=412, Expect=1e-139]; ENSG00000103257, SLC7A5, solute carrier family 7 member 5, [RH, Score=410, Expect=1e-138]} {Mouse: ENSMUSG00000031904, Slc7a6, solute carrier family 7 (cationic amino acid transporter, y+ system), member 6, [RH, Score=419, Expect=2e-142]; ENSMUSG00000027737, Slc7a11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, [RH, Score=413, Expect=3e-140]; ENSMUSG00000000958, Slc7a7, solute carrier family 7 (cationic amino acid transporter, y+ system), member 7, [RH, Score=410, Expect=4e-139]} {Dmel: FBgn0039844, CG1607, [RH, Score=467, Expect=2e-161]} {Celegans: WBGene00000002, aat-1, Amino Acid Transporter, [RH, Score=431, Expect=1e-147]} {Smed: dd_Smed_v6_2179_0_1, dd_Smed_v6_2179_0_1, [RH, Score=498, Expect=5e-174]} {RNA1509_26498} {RNA1310_9422, RNA1509_26498} {RNA1509_26498, RNA815_5493}

Mlig455_020358 {REF} {Length: 3120} {Pfam: Amino acid permease [PF13520.8, score=147.1]; Amino acid permease [PF00324.23, score=74.6]} {Human: ENSG00000103064, SLC7A6, solute carrier family 7 member 6, [Score=346, Expect=6e-115]; ENSG00000155465, SLC7A7, solute carrier family 7 member 7, [Score=340, Expect=2e-112]} {Mouse: ENSMUSG00000031904, Slc7a6, solute carrier family 7 (cationic amino acid transporter, y+ system), member 6, [Score=340, Expect=9e-113]; ENSMUSG00000000958, Slc7a7, solute carrier family 7 (cationic amino acid transporter, y+ system), member 7, [Score=335, Expect=7e-111]; ENSMUSG00000027737, Slc7a11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, [Score=325, Expect=6e-107]} {Dmel: FBgn0039844, CG1607, [Score=390, Expect=1e-132]} {Celegans: WBGene00000002, aat-1, Amino Acid Transporter, [Score=353, Expect=2e-118]} {Smed: dd_Smed_v6_7207_0_1, dd_Smed_v6_7207_0_1, [Score=416, Expect=3e-143]} {RNA1509_56112} {RNA1310_9422, RNA1509_56112} {RNA1509_56112, RNA815_5493}
94. MligTC455_12180 107 2.23 Mlig455_038554, Mlig455_052202, Mlig455_053449

Neo: -

Age: logFC(26M/2M)=-0.655

Region-enriched R2: 5.717/0.01573

CNGA3 4.317 - 0.845 0.870 0.855 0.754 0.993

Mlig455_038554 {REF} {Length: 2866} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=75.9]; Cyclic nucleotide-binding domain [PF00027.31, score=69.1]; Ion transport protein [PF00520.33, score=68.6]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [RH, Score=650, Expect=0.0]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [RH, Score=644, Expect=0.0]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [RH, Score=607, Expect=0.0]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [RH, Score=669, Expect=0.0]} {RNA1310_22950} {RNA815_16119}

Mlig455_052202 {REF} {Length: 3203} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=76.1]; Cyclic nucleotide-binding domain [PF00027.31, score=69.1]; Ion transport protein [PF00520.33, score=68.2]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [RH, Score=650, Expect=0.0]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [RH, Score=644, Expect=0.0]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [RH, Score=605, Expect=0.0]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [RH, Score=667, Expect=0.0]} {RNA1310_22950} {RNA815_16119}

Mlig455_053449 {REF} {Length: 991} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=79.9]; Cyclic nucleotide-binding domain [PF00027.31, score=29.1]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [Score=171, Expect=7e-50]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [Score=161, Expect=2e-46]; ENSMUSG00000067220, Cnga1, cyclic nucleotide gated channel alpha 1, [Score=155, Expect=4e-44]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [Score=148, Expect=1e-41]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [Score=149, Expect=3e-42]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [Score=155, Expect=8e-45]} {RNA1310_61700} {RNA815_16119}
95. MligTC455_40118 72 1.5 Mlig455_001236

Neo: -

Age: -

KCNIP4 4.306 0.712 - 0.885 0.808 0.945 0.956 Mlig455_001236 {REF} {Length: 1284} {Pfam: EF-hand domain pair [PF13499.8, score=42.4]; EF hand [PF00036.34, score=38.6]; EF-hand domain [PF13405.8, score=33.5]; EF hand [PF13202.8, score=31.2]; EF-hand domain pair [PF13833.8, score=28.7]} {Human: ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=122, Expect=2e-32]; ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=122, Expect=2e-32]; ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=119, Expect=1e-30]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=124, Expect=5e-33]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=122, Expect=1e-32]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=100, Expect=6e-25]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=103, Expect=5e-26]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=122, Expect=8e-33]} {RNA1310_43225} {RNA815_33406}
96. MligTC455_45408 287 5.98 Mlig455_042398, Mlig455_042478

Neo: -

Age: logFC(26M/2M)=0.529

TNN 4.302 - 0.740 0.921 0.981 0.754 0.906

Mlig455_042398 {REF} {Length: 1857} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=124.3]; PAN domain [PF00024.28, score=19.2]} {Human: ENSG00000120332, TNN, tenascin N, [Score=98.6, Expect=3e-22]; ENSG00000160339, FCN2, ficolin 2, [Score=94.7, Expect=7e-22]} {Mouse: ENSMUSG00000026725, Tnn, tenascin N, [Score=95.9, Expect=2e-21]; ENSMUSG00000026835, Fcnb, ficolin B, [Score=95.5, Expect=2e-22]; ENSMUSG00000026938, Fcna, ficolin A, [Score=95.1, Expect=5e-22]; ENSMUSG00000028989, Angptl7, angiopoietin-like 7, [Score=91.7, Expect=7e-21]} {Dmel: FBgn0050280, CG30280, [Score=97.8, Expect=1e-23]} {Celegans: WBGene00020516, T15B7.1, [Score=65.9, Expect=6e-12]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=92.4, Expect=8e-21]} {RNA1509_43257} {RNA1310_625, RNA1509_43257} {RNA1509_43257, RNA815_271}

Mlig455_042478 {REF} {Length: 1926} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=124.2]} {Human: ENSG00000120332, TNN, tenascin N, [Score=98.2, Expect=3e-22]; ENSG00000160339, FCN2, ficolin 2, [Score=94.7, Expect=7e-22]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=95.5, Expect=2e-22]; ENSMUSG00000026725, Tnn, tenascin N, [Score=95.5, Expect=2e-21]; ENSMUSG00000026938, Fcna, ficolin A, [Score=95.1, Expect=4e-22]; ENSMUSG00000028989, Angptl7, angiopoietin-like 7, [Score=92.0, Expect=7e-21]} {Dmel: FBgn0050280, CG30280, [Score=97.8, Expect=1e-23]} {Celegans: WBGene00020516, T15B7.1, [Score=65.9, Expect=6e-12]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=92.0, Expect=9e-21]} {RNA1509_43257} {RNA1310_625} {RNA815_271}
97. MligTC455_47874 67 1.4 Mlig455_000340

Neo: -

Age: -

4.299 0.768 - 0.970 0.937 0.916 0.708 Mlig455_000340 {REF} {Length: 1412} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.4, Expect=9e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
98. MligTC455_29030 141 2.93 Mlig455_061986

Neo: -

Age: logFC(26M/2M)=-0.349

Region-enriched R2: 5.117/0.03372

FZD5 4.291 - 0.895 0.718 0.963 0.748 0.967 Mlig455_061986 {REF} {Length: 3701} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=386.1]; Fz domain [PF01392.24, score=95.9]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=582, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=586, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=545, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=388, Expect=7e-127]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [RH, Score=556, Expect=0.0]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
99. MligTC455_41055 112 2.34 Mlig455_044574

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.659

Region-enriched R2: 6.247/0.00008

4.288 - 0.862 0.769 0.951 0.717 0.989 Mlig455_044574 {REF} {Length: 1203} {Smed: dd_Smed_v6_9736_0_1, dd_Smed_v6_9736_0_1, [Score=86.7, Expect=1e-20]} {RNA1509_58567} {RNA1310_87689} {RNA815_53353}
100. MligTC455_40878 355 7.39 Mlig455_014130

Neo: -

Age: -

4.283 0.701 0.771 - 0.928 0.915 0.968 Mlig455_014130 {REF} {Length: 1465} {RNA1509_7458} {RNA1310_36212} {RNA815_1610.1}

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