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Results for MligTC455_16448

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_16448 9758 203.29 Mlig455_027874

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=3.684

Region-enriched R4: 4.613/0.02967

Regeneration-upregulated BL: 7.081

Regeneration-enriched BL: 7.081

HMCN2 Mlig455_027874 {REF} {Length: 2909} {Pfam: von Willebrand factor type A domain [PF13519.8, score=88.9]; von Willebrand factor type A domain [PF00092.30, score=58.4]; DNA gyrase B [PF00204.27, score=20.5]} {Human: ENSG00000148357, HMCN2, hemicentin 2, [Score=80.9, Expect=8e-15]; ENSG00000143341, HMCN1, hemicentin 1, [Score=77.4, Expect=9e-14]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=76.6, Expect=1e-13]; ENSMUSG00000055632, Hmcn2, hemicentin 2, [Score=74.3, Expect=4e-13]; ENSMUSG00000007030, Vwa7, von Willebrand factor A domain containing 7, [Score=73.6, Expect=7e-13]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=88.2, Expect=1e-17]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=80.5, Expect=3e-15]} {RNA1509_30517} {RNA1310_5647.1} {RNA815_1802.1}

Cumulative graph for MligTC455_16448

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -3.842 7.539 1.00000 1.00000
RegionR2 0.929 7.539 0.48661 0.86939
RegionR3 3.532 7.539 0.00535 0.09985
RegionR4 4.613 7.539 0.00386 0.02967
RegionR5 2.54 7.539 0.04027 0.16023
RegionR6 1.409 7.539 0.28094 0.87089
RegionR7 -1.441 7.539 0.99345 1.00000
RegionR8 -7.74 7.539 0.01390 0.22823

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 5.033 7.539 0.04815 0.69012
RegenerationR2 4.408 7.539 0.01265 0.18316
RegenerationR3 2.185 7.539 0.20677 0.64190
RegenerationR4 3.024 7.539 0.10375 0.49719
RegenerationR5 4.252 7.539 0.01298 0.20002
RegenerationR6 4.65 7.539 0.00780 0.10794
RegenerationBL 7.081 7.539 0.00000 0.00014 Specific for BL: 7.081
RegenerationTP 5.867 7.539 0.00471 0.11408


Genes with expression patterns similar to MligTC455_16448

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_16448 9758 203.29 Mlig455_027874

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=3.684

Region-enriched R4: 4.613/0.02967

Regeneration-upregulated BL: 7.081

Regeneration-enriched BL: 7.081

HMCN2 5 - 1.000 1.000 1.000 1.000 1.000 Mlig455_027874 {REF} {Length: 2909} {Pfam: von Willebrand factor type A domain [PF13519.8, score=88.9]; von Willebrand factor type A domain [PF00092.30, score=58.4]; DNA gyrase B [PF00204.27, score=20.5]} {Human: ENSG00000148357, HMCN2, hemicentin 2, [Score=80.9, Expect=8e-15]; ENSG00000143341, HMCN1, hemicentin 1, [Score=77.4, Expect=9e-14]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=76.6, Expect=1e-13]; ENSMUSG00000055632, Hmcn2, hemicentin 2, [Score=74.3, Expect=4e-13]; ENSMUSG00000007030, Vwa7, von Willebrand factor A domain containing 7, [Score=73.6, Expect=7e-13]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=88.2, Expect=1e-17]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=80.5, Expect=3e-15]} {RNA1509_30517} {RNA1310_5647.1} {RNA815_1802.1}
2. MligTC455_48101 874 18.2 Mlig455_018395, Mlig455_069529

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.420/0.02237

LRRC71 1.707 - - - 0.952 - 0.755

Mlig455_018395 {REF} {Length: 2255} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=67.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=25.6]; Leucine Rich Repeat [PF00560.35, score=24.4]} {Human: ENSG00000160838, LRRC71, leucine rich repeat containing 71, [RH, Score=199, Expect=3e-56]} {Mouse: ENSMUSG00000023084, Lrrc71, leucine rich repeat containing 71, [RH, Score=195, Expect=4e-55]} {Smed: dd_Smed_v6_12043_0_2, dd_Smed_v6_12043_0_2, [RH, Score=230, Expect=1e-69]} {RNA1509_18089} {RNA1310_2341.2} {RNA815_677.1}

Mlig455_069529 {REF} {Length: 2441} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=66.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=25.2]; Leucine Rich Repeat [PF00560.35, score=24.2]} {Human: ENSG00000160838, LRRC71, leucine rich repeat containing 71, [RH, Score=202, Expect=2e-57]} {Mouse: ENSMUSG00000023084, Lrrc71, leucine rich repeat containing 71, [RH, Score=198, Expect=4e-56]} {Smed: dd_Smed_v6_12043_0_2, dd_Smed_v6_12043_0_2, [RH, Score=227, Expect=2e-68]} {RNA1509_18089} {RNA1310_2341.2, RNA1509_18089} {RNA1509_18089, RNA815_677.1}
3. MligTC455_44849 3056 63.66 Mlig455_014245

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.313

LEXM 1.689 - 0.726 - 0.963 - - Mlig455_014245 {REF} {Length: 2724} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1} {RNA815_5377}
4. MligTC455_52048 1282 26.72 Mlig455_019679

Neo: -

Age: logFC(26M/2M)=-0.701

0.98 - - - 0.980 - - Mlig455_019679 {REF} {Length: 2281} {Pfam: D-arabinono-1,4-lactone oxidase [PF04030.16, score=40.8]; FAD binding domain [PF01565.25, score=27.1]} {Mouse: ENSMUSG00000034450, Gulo, gulonolactone (L-) oxidase, [Score=55.1, Expect=1e-07]} {Smed: dd_Smed_v6_10292_0_1, dd_Smed_v6_10292_0_1, [Score=127, Expect=4e-31]} {RNA1509_25376, RNA1509_2896} {RNA1310_10814, RNA1509_25376} {RNA1509_25376, RNA815_3783}
5. MligTC455_40019 7651 159.4 Mlig455_008768

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.383

ODF3 0.977 - - - 0.977 - - Mlig455_008768 {REF} {Length: 2865} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=66.8]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=185, Expect=1e-57]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=180, Expect=1e-55]} {Dmel: FBgn0032010, CG8086, [RH, Score=120, Expect=8e-33]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [RH, Score=330, Expect=3e-115]} {RNA1509_29531, RNA1509_587} {RNA1310_15447.1, RNA1509_29531} {RNA1509_29531, RNA815_2683.1}
6. MligTC455_16148 198 4.12 Mlig455_057689

Neo: -

Age: -

KLHDC8A 0.975 - - - 0.975 - - Mlig455_057689 {REF} {Length: 1806} {Pfam: Kelch motif [PF13964.8, score=56.9]; Kelch motif [PF01344.27, score=52.7]; Kelch motif [PF07646.17, score=37.5]; Galactose oxidase, central domain [PF13418.8, score=35.1]; Kelch motif [PF13854.8, score=27.6]} {Human: ENSG00000162873, KLHDC8A, kelch domain containing 8A, [Score=58.5, Expect=2e-09]} {Mouse: ENSMUSG00000042115, Klhdc8a, kelch domain containing 8A, [Score=63.9, Expect=1e-10]} {Smed: dd_Smed_v6_14507_0_1, dd_Smed_v6_14507_0_1, [RH, Score=209, Expect=4e-63]} {RNA1509_58319} {RNA1310_20213} {RNA815_8052}
7. MligTC455_40020 7894 164.45 Mlig455_008800

Neo: -

Age: -

ODF3 0.973 - - - 0.973 - - Mlig455_008800 {REF} {Length: 1876} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=67.2]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=186, Expect=4e-58]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=181, Expect=3e-56]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=3e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [RH, Score=331, Expect=1e-115]} {RNA1509_24509, RNA1509_25204, RNA1509_33091, RNA1509_587} {RNA1310_15447.1, RNA1509_24509, RNA1509_25204, RNA1509_33091, RNA1509_587} {RNA1509_24509, RNA1509_25204, RNA1509_33091, RNA1509_587, RNA815_2683.1}
8. MligTC455_40619 159 3.32 Mlig455_016768

Neo: -

Age: Up-Up-Down

KIF1A 0.967 - - - 0.967 - - Mlig455_016768 {REF} {Length: 6294} {Pfam: Kinesin protein 1B [PF12423.10, score=36.5]; FHA domain [PF00498.28, score=31.0]; Kinesin-associated [PF16183.7, score=19.9]} {Human: ENSG00000130294, KIF1A, kinesin family member 1A, [Score=87.4, Expect=4e-17]; ENSG00000054523, KIF1B, kinesin family member 1B, [Score=85.9, Expect=1e-16]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [Score=212, Expect=5e-58]} {Dmel: FBgn0267002, unc-104, uncoordinated-104, [Score=74.7, Expect=2e-13]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [Score=236, Expect=6e-67]} {Smed: dd_Smed_v6_20223_0_1, dd_Smed_v6_20223_0_1, [Score=512, Expect=3e-172]} {RNA1509_18998} {RNA1310_3422, RNA1509_18998} {RNA1509_18998, RNA815_1532}
9. MligTC455_51921 595 12.39 Mlig455_003170, Mlig455_003371

Neo: -

Age: -

Region-enriched R4: 2.417/0.02426
Region-enriched R5: 1.862/0.01644

SLC26A2 0.967 - - - - 0.967 -

Mlig455_003170 {REF} {Length: 2630} {TRANSSPLICED} {Pfam: Sulfate permease family [PF00916.22, score=265.3]; STAS domain [PF01740.23, score=74.1]} {Human: ENSG00000155850, SLC26A2, solute carrier family 26 member 2, [Score=303, Expect=2e-93]} {Mouse: ENSMUSG00000034320, Slc26a2, solute carrier family 26 (sulfate transporter), member 2, [Score=305, Expect=5e-94]; ENSMUSG00000107138, Slc26a6, solute carrier family 26, member 6, [Score=291, Expect=4e-90]; ENSMUSG00000023259, Slc26a6, solute carrier family 26, member 6, [Score=291, Expect=4e-90]} {Dmel: FBgn0036770, Prestin, [Score=232, Expect=4e-67]} {Celegans: WBGene00010789, sulp-5, SULfate Permease family, [Score=289, Expect=2e-88]} {Smed: dd_Smed_v6_16869_0_1, dd_Smed_v6_16869_0_1, [Score=357, Expect=6e-117]} {RNA1509_19433} {RNA1310_6641.1} {RNA815_11514}

Mlig455_003371 {REF} {Length: 2682} {TRANSSPLICED} {Pfam: Sulfate permease family [PF00916.22, score=284.9]; STAS domain [PF01740.23, score=74.0]} {Human: ENSG00000155850, SLC26A2, solute carrier family 26 member 2, [Score=327, Expect=5e-102]} {Mouse: ENSMUSG00000034320, Slc26a2, solute carrier family 26 (sulfate transporter), member 2, [Score=327, Expect=2e-102]; ENSMUSG00000023259, Slc26a6, solute carrier family 26, member 6, [Score=320, Expect=8e-101]; ENSMUSG00000107138, Slc26a6, solute carrier family 26, member 6, [Score=320, Expect=8e-101]} {Dmel: FBgn0036770, Prestin, [Score=248, Expect=1e-72]} {Celegans: WBGene00010789, sulp-5, SULfate Permease family, [Score=308, Expect=2e-95]} {Smed: dd_Smed_v6_16869_0_1, dd_Smed_v6_16869_0_1, [Score=389, Expect=6e-129]} {RNA1509_19433} {RNA1310_6641.1, RNA1509_19433} {RNA1509_19433, RNA815_11514}
10. MligTC455_43628 537 11.19 Mlig455_001214

Neo: Neoblast, stringent

Age: -

Region-enriched R5: 1.841/0.00696

Regeneration-upregulated BL: 2.235

Regeneration-enriched BL: 2.235

G2E3 0.963 - - - - 0.963 - Mlig455_001214 {REF} {Length: 2124} {Pfam: PHD-like zinc-binding domain [PF13771.8, score=44.7]} {Human: ENSG00000092140, G2E3, G2/M-phase specific E3 ubiquitin protein ligase, [RH, Score=154, Expect=3e-40]} {Mouse: ENSMUSG00000035293, G2e3, G2/M-phase specific E3 ubiquitin ligase, [RH, Score=142, Expect=2e-36]; ENSMUSG00000021902, Phf7, PHD finger protein 7, [RH, Score=137, Expect=9e-37]} {Dmel: FBgn0005683, pie, pineapple eye, [RH, Score=110, Expect=6e-26]} {Smed: dd_Smed_v6_6301_0_1, dd_Smed_v6_6301_0_1, [RH, Score=116, Expect=3e-28]} {RNA1509_27373} {RNA1310_12923.1, RNA1509_27373} {RNA1509_27373, RNA815_4856}
11. MligTC455_38421 370 7.7 Mlig455_044722

Neo: -

Age: Up-Down-Down

NAPRT 0.962 - - - 0.962 - - Mlig455_044722 {REF} {Length: 3922} {TRANSSPLICED} {Pfam: Nicotinate phosphoribosyltransferase C-terminal domain [PF17956.3, score=134.1]; Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain [PF17767.3, score=126.7]; Nicotinate phosphoribosyltransferase (NAPRTase) family [PF04095.18, score=49.5]} {Human: ENSG00000147813, NAPRT, nicotinate phosphoribosyltransferase, [RH, Score=498, Expect=7e-172]; ENSG00000278488, NAPRT, nicotinate phosphoribosyltransferase, [RH, Score=498, Expect=7e-172]} {Mouse: ENSMUSG00000022574, Naprt, nicotinate phosphoribosyltransferase, [RH, Score=500, Expect=5e-173]} {Dmel: FBgn0031589, CG3714, [RH, Score=708, Expect=0.0]} {Celegans: WBGene00021882, nprt-1, Nicotinate phosphoribosyltransferase, [RH, Score=666, Expect=0.0]} {Smed: dd_Smed_v6_12183_0_2, dd_Smed_v6_12183_0_2, [RH, Score=716, Expect=0.0]} {RNA1509_6179} {RNA1310_9656.2} {RNA815_2619.1}
12. MligTC455_53417 2924 60.91 Mlig455_006633

Neo: -

Age: logFC(26M/2M)=-0.635

ZBTB46 0.961 - - - 0.961 - - Mlig455_006633 {REF} {Length: 4244} {Pfam: BTB/POZ domain [PF00651.33, score=45.4]; NPH3 family [PF03000.16, score=40.0]} {Human: ENSG00000130584, ZBTB46, zinc finger and BTB domain containing 46, [Score=51.6, Expect=3e-06]; ENSG00000160062, ZBTB8A, zinc finger and BTB domain containing 8A, [Score=51.2, Expect=3e-06]; ENSG00000117153, KLHL12, kelch like family member 12, [Score=49.3, Expect=1e-05]} {Mouse: ENSMUSG00000026455, Klhl12, kelch-like 12, [Score=50.8, Expect=4e-06]; ENSMUSG00000028807, Zbtb8a, zinc finger and BTB domain containing 8a, [Score=49.7, Expect=7e-06]; ENSMUSG00000027583, Zbtb46, zinc finger and BTB domain containing 46, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_8081_0_1, dd_Smed_v6_8081_0_1, [Score=216, Expect=2e-62]} {RNA1509_2983} {RNA1310_20884} {RNA815_5532.1}
13. MligTC455_01872 209 4.35 Mlig455_030442, Mlig455_069051

Neo: -

Age: -

KATNAL2 0.96 - - - 0.960 - -

Mlig455_030442 {REF} {Length: 3923} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=129.6]; AAA+ lid domain [PF17862.3, score=44.1]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=22.6]; AAA ATPase domain [PF13191.8, score=21.0]; TIP49 P-loop domain [PF06068.15, score=19.2]; AAA domain (dynein-related subfamily) [PF07728.16, score=19.1]} {Human: ENSG00000167216, KATNAL2, katanin catalytic subunit A1 like 2, [RH, Score=579, Expect=0.0]} {Mouse: ENSMUSG00000025420, Katnal2, katanin p60 subunit A-like 2, [Score=562, Expect=0.0]} {Dmel: FBgn0040208, Kat60, Katanin 60, [Score=277, Expect=7e-86]} {Celegans: WBGene00003183, mei-1, Meiotic spindle formation protein mei-1, [Score=249, Expect=1e-76]} {Smed: dd_Smed_v6_14853_0_1, dd_Smed_v6_14853_0_1, [Score=624, Expect=0.0]} {RNA1509_55443} {RNA1310_12620.1} {RNA815_3736}

Mlig455_069051 {REF} {Length: 3790} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=128.9]; AAA+ lid domain [PF17862.3, score=44.0]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=22.5]; AAA ATPase domain [PF13191.8, score=20.1]; TIP49 P-loop domain [PF06068.15, score=19.1]; AAA domain (dynein-related subfamily) [PF07728.16, score=19.0]} {Human: ENSG00000167216, KATNAL2, katanin catalytic subunit A1 like 2, [RH, Score=612, Expect=0.0]} {Mouse: ENSMUSG00000025420, Katnal2, katanin p60 subunit A-like 2, [RH, Score=595, Expect=0.0]} {Dmel: FBgn0040208, Kat60, Katanin 60, [Score=284, Expect=3e-88]} {Celegans: WBGene00003183, mei-1, Meiotic spindle formation protein mei-1, [Score=249, Expect=4e-76]} {Smed: dd_Smed_v6_14853_0_1, dd_Smed_v6_14853_0_1, [RH, Score=662, Expect=0.0]} {RNA1509_55443} {RNA1310_12620.2} {RNA815_3736}
14. MligTC455_25971 151 3.14 Mlig455_009163

Neo: -

Age: -

Regeneration-downregulated BL: -6.673

Regeneration-depleted BL: -6.673

0.96 - - - 0.960 - - Mlig455_009163 {REF} {Length: 2858} {RNA1509_41399} {RNA1310_25715, RNA1509_41399} {RNA1509_41399, RNA815_12763}
15. MligTC455_48827 761 15.86 Mlig455_042518

Neo: -

Age: logFC(26M/2M)=-0.412

ANO7 0.96 - - - 0.960 - - Mlig455_042518 {REF} {Length: 4110} {Pfam: Calcium-activated chloride channel [PF04547.14, score=290.9]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=33.9]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=164, Expect=8e-41]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=165, Expect=1e-41]; ENSMUSG00000031075, Ano1, anoctamin 1, calcium activated chloride channel, [Score=160, Expect=1e-39]; ENSMUSG00000064210, Ano6, anoctamin 6, [Score=157, Expect=4e-39]} {Dmel: FBgn0030349, CG10353, [Score=157, Expect=6e-39]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=263, Expect=3e-75]} {Smed: dd_Smed_v6_19189_0_1, dd_Smed_v6_19189_0_1, [Score=161, Expect=5e-41]} {RNA1509_6346} {RNA1310_5254, RNA1509_6346} {RNA1509_6346, RNA815_4443}
16. MligTC455_27366 36262 755.45 Mlig455_040596, Mlig455_040607, Mlig455_062037

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.976

Region-enriched R4: 2.015/0.00241
Region-enriched R8: 1.429/0.04613

0.959 - - - 0.959 - -

Mlig455_040596 {REF} {Length: 917} {RNA1509_1252} {RNA1310_61787} {RNA815_19934.1}

Mlig455_040607 {REF} {Length: 1621} {RNA1509_1252} {RNA1310_61787} {RNA815_19934.1}

Mlig455_062037 {REF} {Length: 2344} {RNA1509_1252} {RNA1310_61787} {RNA815_19934.1}
17. MligTC455_48050 2232 46.51 Mlig455_010555

Neo: -

Age: logFC(26M/2M)=-0.254

Region-specific R2: 1.866

Region-enriched R2: 1.359/0.00112

0.959 - - - 0.959 - - Mlig455_010555 {REF} {Length: 1509} {RNA1509_46129, RNA1509_6507} {RNA1310_26163, RNA1509_46129, RNA1509_6507} {RNA1509_46129, RNA1509_6507, RNA815_24113}
18. MligTC455_03762 6136 127.84 Mlig455_036177

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.273

CKB 0.957 - - - 0.957 - - Mlig455_036177 {REF} {Length: 7223} {Pfam: ATP:guanido phosphotransferase, C-terminal catalytic domain [PF00217.21, score=1066.2]; ATP:guanido phosphotransferase, N-terminal domain [PF02807.17, score=399.5]; flt3 ligand [PF02947.16, score=36.8]; Nematode polyprotein allergen ABA-1 [PF16469.7, score=31.3]; Domain of unknown function (DUF4581) [PF15167.8, score=25.5]; Latarcin precursor [PF10279.11, score=23.5]; Sir4 SID domain [PF16991.7, score=23.3]; SF-assemblin/beta giardin [PF06705.13, score=22.4]; Small, acid-soluble spore protein I [PF14098.8, score=22.3]; Plectin repeat [PF00681.22, score=21.8]; Ribonuclease toxin, BrnT, of type II toxin-antitoxin system [PF04365.15, score=21.8]; Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) [PF09602.12, score=19.0]} {Human: ENSG00000166165, CKB, creatine kinase B, [RH, Score=296, Expect=3e-89]} {Mouse: ENSMUSG00000001270, Ckb, creatine kinase, brain, [RH, Score=292, Expect=6e-88]; ENSMUSG00000030399, Ckm, creatine kinase, muscle, [RH, Score=286, Expect=9e-86]} {Dmel: FBgn0000116, Argk, Arginine kinase, [RH, Score=550, Expect=1e-180]} {Celegans: WBGene00018519, F46H5.3, Probable arginine kinase F46H5.3, [RH, Score=473, Expect=7e-154]} {Smed: dd_Smed_v6_67158_0_1, dd_Smed_v6_67158_0_1, [RH, Score=252, Expect=7e-76]} {RNA1509_1711} {RNA1310_13046} {RNA815_1372.1}
19. MligTC455_41979 3503 72.98 Mlig455_022271

Neo: -

Age: logFC(26M/2M)=-0.319

0.957 - - - 0.957 - - Mlig455_022271 {REF} {Length: 3465} {Pfam: Domain of unknown function (DUF1330) [PF07045.13, score=28.5]} {Smed: dd_Smed_v6_8243_0_1, dd_Smed_v6_8243_0_1, [Score=117, Expect=5e-31]} {RNA1509_35371, RNA1509_3710, RNA1509_5489} {RNA1310_15598, RNA1509_35371, RNA1509_3710, RNA1509_5489} {RNA1509_35371, RNA1509_3710, RNA1509_5489, RNA815_10198.1}
20. MligTC455_29828 3825 79.69 Mlig455_005927, Mlig455_028571

Neo: -

Age: -

Region-enriched R2: 2.078/0.00752

AOX1 0.956 - - - 0.956 - -

Mlig455_005927 {REF} {Length: 5419} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=393.8]; [2Fe-2S] binding domain [PF01799.22, score=95.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=88.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=82.6]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=60.0]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=21.6]} {Human: ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=461, Expect=1e-139]; ENSG00000158125, XDH, xanthine dehydrogenase, [Score=454, Expect=4e-137]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=468, Expect=2e-142]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=449, Expect=1e-135]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=665, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=506, Expect=1e-156]} {RNA1509_1345} {RNA1310_1703.1, RNA1509_1345} {RNA1509_1345, RNA815_528.1}

Mlig455_028571 {REF} {Length: 5081} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=393.8]; [2Fe-2S] binding domain [PF01799.22, score=95.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=88.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=82.6]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=60.0]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=21.6]} {Human: ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=459, Expect=5e-139]; ENSG00000158125, XDH, xanthine dehydrogenase, [Score=453, Expect=6e-137]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=467, Expect=3e-142]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=450, Expect=9e-136]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=665, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=506, Expect=1e-156]} {RNA1509_1345, RNA1509_30386} {RNA1310_1703.1, RNA1509_30386} {RNA1509_30386, RNA815_528.1}
21. MligTC455_53809 608 12.67 Mlig455_063377

Neo: -

Age: logFC(26M/2M)=-0.339

HUNK 0.956 - - - 0.956 - - Mlig455_063377 {REF} {Length: 4517} {Pfam: Protein kinase domain [PF00069.27, score=241.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=147.5]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=25.3]; Kinase-like [PF14531.8, score=24.3]; RIO1 family [PF01163.24, score=19.0]; Haspin like kinase domain [PF12330.10, score=18.0]} {Human: ENSG00000142149, HUNK, hormonally up-regulated Neu-associated kinase, [RH, Score=382, Expect=1e-120]} {Mouse: ENSMUSG00000053414, Hunk, hormonally upregulated Neu-associated kinase, [RH, Score=385, Expect=1e-121]} {Dmel: FBgn0023169, AMPKalpha, AMP-activated protein kinase alpha subunit, [Score=218, Expect=4e-61]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=226, Expect=2e-61]} {Smed: dd_Smed_v6_2538_0_1, dd_Smed_v6_2538_0_1, [Score=223, Expect=1e-63]} {RNA1509_10302, RNA1509_25913} {RNA1310_5970, RNA1509_10302, RNA1509_25913} {RNA1509_10302, RNA1509_25913, RNA815_9514}
22. MligTC455_21638 50 1.05 Mlig455_026393

Neo: -

Age: Down-Up-Down

SLC6A5 0.955 - - - 0.955 - - Mlig455_026393 {REF} {Length: 1896} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=352.8]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=310, Expect=2e-97]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=309, Expect=3e-97]} {Dmel: FBgn0034911, CG5549, [Score=310, Expect=6e-95]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=226, Expect=2e-67]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=276, Expect=1e-85]} {RNA1509_16390} {RNA1310_7302.2} {RNA815_18232}
23. MligTC455_31859 3496 72.84 Mlig455_029320

Neo: -

Age: logFC(26M/2M)=-0.188

CBR1 0.955 - - - 0.955 - - Mlig455_029320 {REF} {Length: 1931} {TRANSSPLICED} {Pfam: short chain dehydrogenase [PF00106.27, score=114.4]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=96.4]; KR domain [PF08659.12, score=27.6]; NAD dependent epimerase/dehydratase family [PF01370.23, score=24.9]} {Human: ENSG00000159228, CBR1, carbonyl reductase 1, [RH, Score=266, Expect=7e-89]} {Mouse: ENSMUSG00000051483, Cbr1, carbonyl reductase 1, [RH, Score=262, Expect=3e-87]; ENSMUSG00000022947, Cbr3, carbonyl reductase 3, [RH, Score=255, Expect=2e-84]; ENSMUSG00000082815, Gm5678, predicted gene 5678, [RH, Score=254, Expect=5e-84]} {Dmel: FBgn0034500, CG11200, Carbonyl reductase, [Score=60.5, Expect=3e-10]} {Celegans: WBGene00008336, C55A6.7, [Score=77.0, Expect=2e-16]} {Smed: dd_Smed_v6_2165_0_1, dd_Smed_v6_2165_0_1, [RH, Score=306, Expect=9e-105]} {RNA1509_22325} {RNA1310_31623} {RNA815_11800.2}
24. MligTC455_44850 2381 49.6 Mlig455_014259

Neo: -

Age: logFC(26M/2M)=-0.355

LEXM 0.955 - - - 0.955 - - Mlig455_014259 {REF} {Length: 2739} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1, RNA1509_2011} {RNA1509_2011, RNA815_5377}
25. MligTC455_33131 549 11.45 Mlig455_022594, Mlig455_026005, Mlig455_070429

Neo: Germline

Age: logFC(26M/2M)=-0.432

KY 0.953 - - - 0.953 - -

Mlig455_022594 {REF} {Length: 667} {Pfam: Helix-turn-helix domain of transposase family ISL3 [PF13542.8, score=27.8]} {RNA1509_53064} {RNA1310_18119} {RNA815_4493}

Mlig455_026005 {REF} {Length: 5002} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=94.7, Expect=2e-19]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=95.5, Expect=1e-19]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=105, Expect=1e-22]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=105, Expect=2e-23]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=111, Expect=1e-24]} {RNA1509_11170} {RNA1310_2597.1} {RNA815_17158}

Mlig455_070429 {REF} {Length: 5697} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=97.4, Expect=5e-20]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=96.7, Expect=6e-20]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=113, Expect=4e-25]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=113, Expect=3e-25]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=113, Expect=4e-25]} {RNA1509_11170, RNA1509_29877} {RNA1310_2597.1, RNA1509_11170, RNA1509_29877} {RNA1509_11170, RNA1509_29877, RNA815_3609}
26. MligTC455_32149 36 0.75 Mlig455_033666

Neo: -

Age: Up-Down-Up

0.952 - - - 0.952 - - Mlig455_033666 {REF} {Length: 2371} {Pfam: Ribosomal protein S31e [PF17067.7, score=24.1]} {RNA1509_26752} {RNA1310_51800} {RNA815_53946}
27. MligTC455_35416 312 6.5 Mlig455_025858

Neo: -

Age: Down-Down-Up

Region-enriched R2: 2.218/0.01756

0.952 - - - 0.952 - - Mlig455_025858 {REF} {Length: 2565} {RNA1509_8462} {RNA1310_23985, RNA1509_8462} {RNA1509_8462, RNA815_9218.1}
28. MligTC455_40398 107 2.23 Mlig455_065346

Neo: -

Age: logFC(26M/2M)=-0.357

UCHL3 0.952 - - - - 0.952 - Mlig455_065346 {REF} {Length: 1850} {Pfam: Ubiquitin carboxyl-terminal hydrolase, family 1 [PF01088.23, score=190.9]} {Human: ENSG00000118939, UCHL3, ubiquitin C-terminal hydrolase L3, [RH, Score=201, Expect=9e-65]} {Mouse: ENSMUSG00000022111, Uchl3, ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase), [RH, Score=201, Expect=6e-65]; ENSMUSG00000035337, Uchl4, ubiquitin carboxyl-terminal esterase L4, [RH, Score=192, Expect=4e-61]} {Dmel: FBgn0010288, Uch, Ubiquitin carboxy-terminal hydrolase, [RH, Score=172, Expect=8e-54]} {Celegans: WBGene00006721, ubh-1, Ubiquitin carboxyl-terminal hydrolase, [RH, Score=110, Expect=1e-29]} {Smed: dd_Smed_v6_7488_0_1, dd_Smed_v6_7488_0_1, [RH, Score=187, Expect=6e-60]} {RNA1509_16357} {RNA1310_29575} {RNA815_15587}
29. MligTC455_41200 1715 35.72 Mlig455_069721

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.691

CFAP45 0.951 - - - 0.951 - - Mlig455_069721 {REF} {Length: 2678} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=268.3]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [Score=327, Expect=2e-105]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [Score=317, Expect=1e-101]} {Dmel: FBgn0037162, CG11449, [RH, Score=114, Expect=1e-26]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [Score=434, Expect=4e-147]} {RNA1509_11293, RNA1509_455, RNA1509_48510, RNA1509_5508} {RNA1310_7881.1, RNA1509_11293, RNA1509_48510, RNA1509_5508} {RNA1509_11293, RNA1509_48510, RNA1509_5508, RNA815_2376.1}
30. MligTC455_31858 7190 149.78 Mlig455_029298, Mlig455_058870

Neo: -

Age: -

CBR1 0.95 - - - 0.950 - -

Mlig455_029298 {REF} {Length: 1102} {TRANSSPLICED} {Pfam: short chain dehydrogenase [PF00106.27, score=118.0]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=98.1]; KR domain [PF08659.12, score=27.3]} {Human: ENSG00000159228, CBR1, carbonyl reductase 1, [RH, Score=265, Expect=2e-88]} {Mouse: ENSMUSG00000051483, Cbr1, carbonyl reductase 1, [RH, Score=263, Expect=9e-88]; ENSMUSG00000022947, Cbr3, carbonyl reductase 3, [RH, Score=259, Expect=5e-86]; ENSMUSG00000082815, Gm5678, predicted gene 5678, [RH, Score=255, Expect=2e-84]} {Dmel: FBgn0051235, CG31235, [Score=63.2, Expect=4e-11]} {Celegans: WBGene00008336, C55A6.7, [Score=77.0, Expect=2e-16]} {Smed: dd_Smed_v6_2165_0_1, dd_Smed_v6_2165_0_1, [RH, Score=307, Expect=2e-105]} {RNA1509_41289} {RNA1310_31623} {RNA815_11800.2}

Mlig455_058870 {REF} {Length: 1102} {TRANSSPLICED} {Pfam: short chain dehydrogenase [PF00106.27, score=114.9]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=94.5]; KR domain [PF08659.12, score=26.6]} {Human: ENSG00000159228, CBR1, carbonyl reductase 1, [RH, Score=266, Expect=2e-88]} {Mouse: ENSMUSG00000051483, Cbr1, carbonyl reductase 1, [RH, Score=263, Expect=1e-87]; ENSMUSG00000022947, Cbr3, carbonyl reductase 3, [RH, Score=258, Expect=2e-85]; ENSMUSG00000082815, Gm5678, predicted gene 5678, [RH, Score=254, Expect=2e-84]} {Dmel: FBgn0051235, CG31235, [Score=63.2, Expect=5e-11]} {Celegans: WBGene00008336, C55A6.7, [Score=77.0, Expect=2e-16]} {Smed: dd_Smed_v6_2165_0_1, dd_Smed_v6_2165_0_1, [RH, Score=307, Expect=2e-105]} {RNA1509_41289} {RNA1310_31623} {RNA815_11800.2}

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