Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_21985 | 187 | 3.89 | Mlig455_024467 | Neo: - Age: Down-Up-Down |
NT5E | Mlig455_024467 {REF} {Length: 2710} {Pfam: 5'-nucleotidase, C-terminal domain [PF02872.20, score=110.1]; Calcineurin-like phosphoesterase [PF00149.30, score=42.8]} {Human: ENSG00000135318, NT5E, 5'-nucleotidase ecto, [RH, Score=102, Expect=4e-22]} {Mouse: ENSMUSG00000021718, 4933425L06Rik, RIKEN cDNA 4933425L06 gene, [RH, Score=382, Expect=1e-125]} {Dmel: FBgn0033538, CG11883, [RH, Score=459, Expect=3e-153]} {Smed: dd_Smed_v6_3474_0_1, dd_Smed_v6_3474_0_1, [RH, Score=464, Expect=2e-158]} {RNA1509_22709} {RNA1310_12561, RNA1509_22709} {RNA1509_22709, RNA815_22779} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -5.609 | 2.541 | 0.20279 | 0.84126 | |
RegionR2 | 1.534 | 2.541 | 0.10423 | 0.39790 | |
RegionR3 | 0.37 | 2.541 | 0.67449 | 1.00000 | |
RegionR4 | -0.093 | 2.541 | 0.88283 | 1.00000 | |
RegionR5 | 0.638 | 2.541 | 0.46683 | 0.82910 | |
RegionR6 | 0.656 | 2.541 | 0.48061 | 1.00000 | |
RegionR7 | 0.814 | 2.541 | 0.45006 | 1.00000 | |
RegionR8 | 1.69 | 2.541 | 0.10914 | 0.61489 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 0.38 | 2.541 | 0.99993 | 1.00000 | |
RegenerationR2 | -0.495 | 2.541 | 0.35415 | 0.78450 | |
RegenerationR3 | 0.38 | 2.541 | 0.55827 | 0.88771 | |
RegenerationR4 | -0.255 | 2.541 | 0.71029 | 0.95751 | |
RegenerationR5 | -0.51 | 2.541 | 0.37896 | 0.78642 | |
RegenerationR6 | -0.481 | 2.541 | 0.48933 | 0.79859 | |
RegenerationBL | 0.674 | 2.541 | 0.33303 | 0.69970 | |
RegenerationTP | -2.51 | 2.541 | 0.02568 | 0.27059 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_21985 | 187 | 3.89 | Mlig455_024467 | Neo: - Age: Down-Up-Down |
NT5E | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_024467 {REF} {Length: 2710} {Pfam: 5'-nucleotidase, C-terminal domain [PF02872.20, score=110.1]; Calcineurin-like phosphoesterase [PF00149.30, score=42.8]} {Human: ENSG00000135318, NT5E, 5'-nucleotidase ecto, [RH, Score=102, Expect=4e-22]} {Mouse: ENSMUSG00000021718, 4933425L06Rik, RIKEN cDNA 4933425L06 gene, [RH, Score=382, Expect=1e-125]} {Dmel: FBgn0033538, CG11883, [RH, Score=459, Expect=3e-153]} {Smed: dd_Smed_v6_3474_0_1, dd_Smed_v6_3474_0_1, [RH, Score=464, Expect=2e-158]} {RNA1509_22709} {RNA1310_12561, RNA1509_22709} {RNA1509_22709, RNA815_22779} |
2. | MligTC455_17431 | 150 | 3.13 | Mlig455_010055, Mlig455_063265 | Neo: - Age: - |
PPP2R2A | 1.878 | - | - | - | - | 0.962 | 0.916 | Mlig455_010055 {REF} {Length: 4204} {Pfam: WD domain, G-beta repeat [PF00400.34, score=44.6]} {Human: ENSG00000221914, PPP2R2A, protein phosphatase 2 regulatory subunit Balpha, [RH, Score=598, Expect=0.0]; ENSG00000175470, PPP2R2D, protein phosphatase 2 regulatory subunit Bdelta, [RH, Score=594, Expect=0.0]; ENSG00000156475, PPP2R2B, protein phosphatase 2 regulatory subunit Bbeta, [RH, Score=590, Expect=0.0]; ENSG00000074211, PPP2R2C, protein phosphatase 2 regulatory subunit Bgamma, [RH, Score=578, Expect=0.0]} {Mouse: ENSMUSG00000022052, Ppp2r2a, protein phosphatase 2, regulatory subunit B, alpha, [RH, Score=598, Expect=0.0]; ENSMUSG00000041769, Ppp2r2d, protein phosphatase 2, regulatory subunit B, delta, [RH, Score=596, Expect=0.0]; ENSMUSG00000024500, Ppp2r2b, protein phosphatase 2, regulatory subunit B, beta, [RH, Score=577, Expect=0.0]; ENSMUSG00000029120, Ppp2r2c, protein phosphatase 2, regulatory subunit B, gamma, [RH, Score=574, Expect=0.0]} {Dmel: FBgn0004889, tws, twins, [RH, Score=585, Expect=0.0]} {Celegans: WBGene00006352, sur-6, Serine/threonine-protein phosphatase 2A regulatory subunit sur-6, [RH, Score=548, Expect=0.0]} {Smed: dd_Smed_v6_5857_0_1, dd_Smed_v6_5857_0_1, [RH, Score=536, Expect=0.0]} {RNA1509_26565} {RNA1310_5980.2} {RNA815_10468} Mlig455_063265 {REF} {Length: 5058} {Pfam: WD domain, G-beta repeat [PF00400.34, score=44.9]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=19.1]} {Human: ENSG00000221914, PPP2R2A, protein phosphatase 2 regulatory subunit Balpha, [RH, Score=595, Expect=0.0]; ENSG00000175470, PPP2R2D, protein phosphatase 2 regulatory subunit Bdelta, [RH, Score=592, Expect=0.0]; ENSG00000156475, PPP2R2B, protein phosphatase 2 regulatory subunit Bbeta, [RH, Score=587, Expect=0.0]; ENSG00000074211, PPP2R2C, protein phosphatase 2 regulatory subunit Bgamma, [RH, Score=575, Expect=0.0]} {Mouse: ENSMUSG00000022052, Ppp2r2a, protein phosphatase 2, regulatory subunit B, alpha, [RH, Score=595, Expect=0.0]; ENSMUSG00000041769, Ppp2r2d, protein phosphatase 2, regulatory subunit B, delta, [RH, Score=593, Expect=0.0]; ENSMUSG00000024500, Ppp2r2b, protein phosphatase 2, regulatory subunit B, beta, [RH, Score=574, Expect=0.0]; ENSMUSG00000029120, Ppp2r2c, protein phosphatase 2, regulatory subunit B, gamma, [RH, Score=571, Expect=0.0]} {Dmel: FBgn0004889, tws, twins, [RH, Score=582, Expect=0.0]} {Celegans: WBGene00006352, sur-6, Serine/threonine-protein phosphatase 2A regulatory subunit sur-6, [RH, Score=544, Expect=0.0]} {Smed: dd_Smed_v6_5857_0_1, dd_Smed_v6_5857_0_1, [RH, Score=533, Expect=0.0]} {RNA1509_40500} {RNA1310_5980.1, RNA1509_40500} {RNA1509_40500, RNA815_10468} |
3. | MligTC455_24052 | 272 | 5.66 | Mlig455_065284, Mlig455_065290 | Neo: - Age: Down-Up-Down |
0.967 | - | - | - | - | 0.967 | - | Mlig455_065284 {REF} {Length: 1698} {RNA1509_34738} {RNA1310_59354} {RNA815_53074} Mlig455_065290 {REF} {Length: 3344} {TRANSSPLICED} {Pfam: EamA-like transporter family [PF00892.22, score=24.1]} {RNA1509_34738} {RNA1310_59354} {RNA815_26334} |
|
4. | MligTC455_44539 | 510 | 10.62 | Mlig455_019095 | Neo: Irradiation Age: logFC(26M/2M)=0.310 Regeneration-upregulated BL: 1.934 Regeneration-enriched BL: 1.934 |
AATF | 0.966 | - | - | - | - | 0.966 | - | Mlig455_019095 {REF} {Length: 2406} {TRANSSPLICED} {Pfam: Apoptosis-antagonizing transcription factor, C-terminal [PF08164.14, score=47.5]; Apoptosis antagonizing transcription factor [PF13339.8, score=33.0]} {Human: ENSG00000275700, AATF, apoptosis antagonizing transcription factor, [RH, Score=82.8, Expect=5e-17]; ENSG00000276072, AATF, apoptosis antagonizing transcription factor, [RH, Score=82.8, Expect=5e-17]} {Mouse: ENSMUSG00000018697, Aatf, apoptosis antagonizing transcription factor, [RH, Score=80.5, Expect=2e-16]} {Dmel: FBgn0031851, Aatf, Apoptosis antagonizing transcription factor, [RH, Score=84.3, Expect=7e-18]} {Celegans: WBGene00022269, Y73E7A.2, [Score=54.7, Expect=3e-08]} {RNA1509_19298, RNA1509_23937, RNA1509_7479} {RNA1310_30685.1, RNA1509_19298, RNA1509_23937, RNA1509_7479} {RNA1509_19298, RNA1509_23937, RNA1509_7479, RNA815_21622} |
5. | MligTC455_39869 | 166 | 3.46 | Mlig455_056443, Mlig455_056448 | Neo: - Age: Down-Up-Up |
0.964 | - | - | - | - | 0.964 | - | Mlig455_056443 {REF} {Length: 1590} {RNA1509_28547} {RNA1310_8341} {RNA815_28889} Mlig455_056448 {REF} {Length: 1721} {NoTransDecoderORF} {RNA1509_28547} {RNA1310_8341} {RNA815_28889} |
|
6. | MligTC455_49245 | 304 | 6.33 | Mlig455_050967 | Neo: - Age: Down-Up-Up |
0.962 | - | - | - | - | 0.962 | - | Mlig455_050967 {REF} {Length: 1451} {RNA1310_27401} {RNA815_10632} | |
7. | MligTC455_50156 | 379 | 7.9 | Mlig455_061886 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-0.454 Regeneration-upregulated BL: 2.171 Regeneration-enriched BL: 2.171 |
BEST2 | 0.959 | - | - | - | - | 0.959 | - | Mlig455_061886 {REF} {Length: 2189} {Pfam: Bestrophin, RFP-TM, chloride channel [PF01062.23, score=157.1]} {Human: ENSG00000039987, BEST2, bestrophin 2, [Score=102, Expect=2e-22]} {Mouse: ENSMUSG00000052819, Best2, bestrophin 2, [Score=102, Expect=5e-23]} {Dmel: FBgn0040238, Best1, Bestrophin 1, [Score=181, Expect=1e-49]} {Celegans: WBGene00014989, best-23, Bestrophin homolog, [Score=144, Expect=3e-38]} {Smed: dd_Smed_v6_3859_0_1, dd_Smed_v6_3859_0_1, [Score=233, Expect=5e-71]} {RNA1509_12991, RNA1509_40942} {RNA1310_14129.1, RNA1509_12991, RNA1509_40942} {RNA1509_12991, RNA1509_40942, RNA815_5240} |
8. | MligTC455_35373 | 50 | 1.03 | Mlig455_065912, Mlig455_070019 | Neo: - Age: Down-Up-Down Regeneration-upregulated BL: 7.651 Regeneration-enriched BL: 7.651 |
GLRA2 | 0.957 | - | - | - | - | 0.957 | - | Mlig455_065912 {REF} {Length: 3290} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=157.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=121.2]} {Human: ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=327, Expect=1e-106]; ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=321, Expect=2e-104]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=319, Expect=1e-103]} {Mouse: ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=325, Expect=4e-106]; ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=323, Expect=3e-105]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=317, Expect=3e-103]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=313, Expect=2e-101]} {Dmel: FBgn0024963, GluClalpha, [Score=291, Expect=5e-93]} {Celegans: WBGene00001587, ggr-2, GABA/Glycine Receptor family (See gbr), [RH, Score=249, Expect=2e-76]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=283, Expect=3e-90]} {RNA1509_32923} {RNA1310_14629.1} {RNA815_27491} Mlig455_070019 {REF} {Length: 4890} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=157.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=120.3]} {Human: ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=326, Expect=2e-106]; ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=323, Expect=4e-105]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=318, Expect=2e-103]} {Mouse: ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=325, Expect=5e-106]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=324, Expect=7e-106]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=317, Expect=6e-103]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=313, Expect=1e-101]} {Dmel: FBgn0024963, GluClalpha, [Score=288, Expect=7e-92]} {Celegans: WBGene00001587, ggr-2, GABA/Glycine Receptor family (See gbr), [RH, Score=249, Expect=2e-76]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=284, Expect=2e-90]} {RNA1509_32923} {RNA1310_14629.1} {RNA815_27491} |
9. | MligTC455_39827 | 59 | 1.23 | Mlig455_069154 | Neo: - Age: Down-Down-Up |
SUFU | 0.954 | - | - | - | - | - | 0.954 | Mlig455_069154 {REF} {Length: 2878} {TRANSSPLICED} {Pfam: Suppressor of fused protein (SUFU) [PF05076.15, score=115.3]; Suppressor of Fused Gli/Ci N terminal binding domain [PF12470.10, score=83.7]} {Human: ENSG00000107882, SUFU, SUFU negative regulator of hedgehog signaling, [RH, Score=229, Expect=4e-70]} {Mouse: ENSMUSG00000025231, Sufu, SUFU negative regulator of hedgehog signaling, [RH, Score=209, Expect=2e-62]} {Dmel: FBgn0005355, Su(fu), Suppressor of fused, [RH, Score=187, Expect=1e-54]} {Smed: dd_Smed_v6_10354_0_1, dd_Smed_v6_10354_0_1, [RH, Score=197, Expect=1e-58]} {RNA1509_14191} {RNA1310_26619} {RNA815_22563} |
10. | MligTC455_41048 | 764 | 15.92 | Mlig455_045087 | Neo: - Age: logFC(26M/2M)=-0.302 |
TBX2 | 0.953 | - | - | - | - | 0.953 | - | Mlig455_045087 {REF} {Length: 2264} {Pfam: T-box [PF00907.24, score=261.7]} {Human: ENSG00000121068, TBX2, T-box 2, [Score=321, Expect=3e-101]; ENSG00000135111, TBX3, T-box 3, [Score=317, Expect=3e-99]} {Mouse: ENSMUSG00000018604, Tbx3, T-box 3, [Score=325, Expect=7e-103]; ENSMUSG00000000093, Tbx2, T-box 2, [Score=320, Expect=6e-101]} {Dmel: FBgn0000179, bi, bifid, [Score=320, Expect=8e-99]} {Celegans: WBGene00006543, tbx-2, T-box protein 2, [Score=288, Expect=2e-92]} {Smed: dd_Smed_v6_11693_0_1, dd_Smed_v6_11693_0_1, [Score=322, Expect=8e-103]} {RNA1509_19743, RNA1509_48603} {RNA1310_24036, RNA1509_19743, RNA1509_48603} {RNA1509_19743, RNA1509_48603, RNA815_18470} |
11. | MligTC455_06821 | 8 | 0.17 | Mlig455_032088 | Neo: - Age: - |
CAPN8 | 0.95 | - | - | - | - | 0.950 | - | Mlig455_032088 {REF} {Length: 3116} {Pfam: Calpain family cysteine protease [PF00648.23, score=284.3]; Calpain large subunit, domain III [PF01067.24, score=32.7]} {Human: ENSG00000203697, CAPN8, calpain 8, [Score=233, Expect=1e-68]; ENSG00000135773, CAPN9, calpain 9, [Score=229, Expect=2e-67]; ENSG00000137225, CAPN11, calpain 11, [Score=229, Expect=2e-67]} {Mouse: ENSMUSG00000031981, Capn9, calpain 9, [Score=238, Expect=6e-71]; ENSMUSG00000038599, Capn8, calpain 8, [Score=230, Expect=6e-68]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=225, Expect=2e-67]} {Celegans: WBGene00000546, clp-6, CaLPain family, [Score=216, Expect=1e-63]} {Smed: dd_Smed_v6_1752_0_4, dd_Smed_v6_1752_0_4, [Score=225, Expect=7e-66]} {RNA1509_52904} {RNA1310_59215} {RNA815_23274} |
12. | MligTC455_08185 | 626 | 13.04 | Mlig455_054705 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-1.216 Regeneration-downregulated TP: -3.161 Regeneration-depleted TP: -3.161 |
0.95 | - | - | - | - | 0.950 | - | Mlig455_054705 {REF} {Length: 3519} {Pfam: Immunoglobulin domain [PF13927.8, score=34.9]; Immunoglobulin I-set domain [PF07679.18, score=31.1]; Immunoglobulin domain [PF00047.27, score=19.9]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=49.7, Expect=1e-05]} {RNA1509_36313} {RNA1310_3850.1, RNA1509_36313} {RNA1509_36313, RNA815_412} |