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Results for MligTC455_22349

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_22349 52555 1094.88 Mlig455_033899

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.898

Mlig455_033899 {REF} {Length: 1119} {Pfam: ML domain [PF02221.17, score=50.3]} {RNA1509_17367, RNA1509_52, RNA1509_9444} {RNA1310_15986.1, RNA1509_17367, RNA1509_52} {RNA1509_17367, RNA1509_52, RNA815_5573.1}

Cumulative graph for MligTC455_22349

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.175 10.124 0.70056 1.00000
RegionR2 -0.294 10.124 0.49927 0.87872
RegionR3 0.548 10.124 0.15026 0.65743
RegionR4 0.024 10.124 0.95562 1.00000
RegionR5 0.075 10.124 0.84463 1.00000
RegionR6 0.018 10.124 0.96225 1.00000
RegionR7 -0.209 10.124 0.58933 1.00000
RegionR8 -0.337 10.124 0.41102 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.419 10.124 0.43429 1.00000
RegenerationR2 -0.477 10.124 0.35030 0.78180
RegenerationR3 -1.193 10.124 0.01938 0.25505
RegenerationR4 -1.139 10.124 0.03033 0.28148
RegenerationR5 -0.122 10.124 0.81243 0.99232
RegenerationR6 -0.64 10.124 0.21025 0.55331
RegenerationBL -1.27 10.124 0.00562 0.07087
RegenerationTP -0.134 10.124 0.76956 1.00000


Genes with expression patterns similar to MligTC455_22349

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_22349 52555 1094.88 Mlig455_033899

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.898

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_033899 {REF} {Length: 1119} {Pfam: ML domain [PF02221.17, score=50.3]} {RNA1509_17367, RNA1509_52, RNA1509_9444} {RNA1310_15986.1, RNA1509_17367, RNA1509_52} {RNA1509_17367, RNA1509_52, RNA815_5573.1}
2. MligTC455_45192 47540 990.41 Mlig455_048027

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.977/0.00532

PRSS48 2.518 - 0.735 0.829 - 0.954 - Mlig455_048027 {REF} {Length: 1394} {Pfam: Trypsin [PF00089.28, score=156.4]; Trypsin-like peptidase domain [PF13365.8, score=33.7]} {Human: ENSG00000189099, PRSS48, serine protease 48, [Score=129, Expect=7e-35]; ENSG00000285141, PRSS55, serine protease 55, [Score=127, Expect=5e-34]; ENSG00000184647, PRSS55, serine protease 55, [Score=127, Expect=6e-34]} {Mouse: ENSMUSG00000034623, Prss55, protease, serine 55, [Score=128, Expect=5e-35]; ENSMUSG00000030713, Klk7, kallikrein related-peptidase 7 (chymotryptic, stratum corneum), [Score=125, Expect=2e-34]} {Dmel: FBgn0085487, CG34458, [Score=107, Expect=1e-27]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [Score=87.0, Expect=5e-20]} {Smed: dd_Smed_v6_4570_0_1, dd_Smed_v6_4570_0_1, [RH, Score=165, Expect=7e-50]} {RNA1509_10468, RNA1509_21662, RNA1509_23849, RNA1509_2598, RNA1509_3174, RNA1509_37231, RNA1509_428, RNA1509_563, RNA1509_6099, RNA1509_8021, RNA1509_9652} {RNA1310_33503, RNA1509_10468, RNA1509_21662, RNA1509_23849, RNA1509_2598, RNA1509_3174, RNA1509_37231, RNA1509_428, RNA1509_563, RNA1509_6099, RNA1509_8021, RNA1509_9652} {RNA1509_10468, RNA1509_21662, RNA1509_23849, RNA1509_2598, RNA1509_3174, RNA1509_37231, RNA1509_428, RNA1509_563, RNA1509_6099, RNA1509_8021, RNA1509_9652, RNA815_13628.1}
3. MligTC455_21832 42554 886.53 Mlig455_014096

Neo: -

Age: -

Region-enriched R3: 1.639/0.00213
Region-enriched R4: 1.243/0.04997

1.74 - - 0.782 - 0.958 - Mlig455_014096 {REF} {Length: 1769} {Pfam: Ependymin [PF00811.20, score=62.5]} {RNA1509_105, RNA1509_30580, RNA1509_37256, RNA1509_5561} {RNA1310_28495, RNA1509_105, RNA1509_30580, RNA1509_37256, RNA1509_5561} {RNA1509_105, RNA1509_30580, RNA1509_37256, RNA1509_5561, RNA815_4988.1}
4. MligTC455_21831 42477 884.94 Mlig455_014077

Neo: -

Age: -

Region-enriched R3: 1.642/0.00210
Region-enriched R4: 1.246/0.04930

1.732 - - 0.778 - 0.954 - Mlig455_014077 {REF} {Length: 1771} {Pfam: Ependymin [PF00811.20, score=62.4]} {RNA1509_2190, RNA1509_5561} {RNA1310_28495, RNA1509_2190} {RNA1509_2190, RNA815_4988.1}
5. MligTC455_32712 35891 747.73 Mlig455_006504

Neo: Germline

Age: Down-Up-Down

WBP2NL 1.726 - 0.774 - - 0.952 - Mlig455_006504 {REF} {Length: 1205} {Human: ENSG00000183066, WBP2NL, WBP2 N-terminal like, [RH, Score=54.7, Expect=3e-08]} {Mouse: ENSMUSG00000022455, Wbp2nl, WBP2 N-terminal like, [Score=59.3, Expect=1e-09]} {RNA1509_47} {RNA1310_34773.1} {RNA815_15363.2}
6. MligTC455_31553 39602 825.04 Mlig455_062799

Neo: -

Age: -

Region-enriched R3: 2.267/0.00002
Region-enriched R4: 1.608/0.02050
Region-enriched R5: 1.361/0.02274

1.721 - - 0.736 - 0.985 - Mlig455_062799 {REF} {Length: 3138} {Pfam: 4'-phosphopantetheinyl transferase superfamily [PF01648.22, score=55.6]; Crp-like helix-turn-helix domain [PF13545.8, score=52.0]; Family of unknown function (DUF6307) [PF19826.1, score=49.3]; CUT domain [PF02376.17, score=48.7]; Ribosomal protein L10 [PF00466.22, score=47.5]; Family of unknown function (DUF6470) [PF20074.1, score=43.4]; Wolframin Sel1-like repeat [PF20023.1, score=41.9]; MarR family [PF01047.24, score=38.0]; Effector Associated Constant Component 1 [PF19953.1, score=34.8]; PASTA domain [PF03793.21, score=32.2]; D-lactate dehydrogenase, membrane binding [PF09330.13, score=32.0]; winged helix-turn-helix [PF16221.7, score=27.1]; Helicase HerA, central domain [PF01935.19, score=26.2]; Phage-related minor tail protein [PF10145.11, score=24.9]; von Willebrand factor type A domain [PF13768.8, score=24.4]; Mobile element transfer protein [PF05122.15, score=23.2]; SprT-like family [PF10263.11, score=23.1]; BetR domain [PF08667.12, score=22.4]; ATP synthase alpha/beta family, nucleotide-binding domain [PF00006.27, score=19.7]} {RNA1509_147, RNA1509_1612, RNA1509_34352, RNA1509_37286, RNA1509_3998} {RNA1310_28506, RNA1509_1612, RNA1509_34352, RNA1509_37286, RNA1509_3998} {RNA1509_1612, RNA1509_34352, RNA1509_37286, RNA1509_3998, RNA815_10064}
7. MligTC455_31552 39585 824.68 Mlig455_003092

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.280/0.00005
Region-enriched R4: 1.564/0.03515
Region-enriched R5: 1.361/0.03028

1.702 - - 0.727 - 0.975 - Mlig455_003092 {REF} {Length: 2610} {Pfam: 4'-phosphopantetheinyl transferase superfamily [PF01648.22, score=51.3]; Wolframin Sel1-like repeat [PF20023.1, score=42.9]; Crp-like helix-turn-helix domain [PF13545.8, score=42.7]; Ribosomal protein L10 [PF00466.22, score=39.8]; Family of unknown function (DUF6470) [PF20074.1, score=39.6]; MarR family [PF01047.24, score=38.0]; CUT domain [PF02376.17, score=36.3]; Family of unknown function (DUF6307) [PF19826.1, score=34.2]; PASTA domain [PF03793.21, score=28.6]; Effector Associated Constant Component 1 [PF19953.1, score=28.6]; winged helix-turn-helix [PF16221.7, score=27.0]; Skp1 family, tetramerisation domain [PF03931.17, score=26.8]; Pox virus E6 protein [PF04656.14, score=25.1]; D-lactate dehydrogenase, membrane binding [PF09330.13, score=25.0]; SprT-like family [PF10263.11, score=24.3]; con80 domain of Katanin [PF13925.8, score=22.5]; Helicase HerA, central domain [PF01935.19, score=22.4]; von Willebrand factor type A domain [PF13768.8, score=21.9]; Mobile element transfer protein [PF05122.15, score=21.8]; HMGL-like [PF00682.21, score=20.4]; BetR domain [PF08667.12, score=19.8]} {RNA1509_5885} {RNA1310_14862.1} {RNA815_10064}
8. MligTC455_28659 416 8.67 Mlig455_024182

Neo: -

Age: Up-Down-Down

1.698 - 0.744 - - 0.954 - Mlig455_024182 {REF} {Length: 2105} {RNA1509_38550} {RNA1310_39388.2} {RNA815_16516.1}
9. MligTC455_22584 1485 30.94 Mlig455_037833

Neo: -

Age: Up-Down-Down

Region-enriched R5: 5.505/0.00077

0.985 - - - - 0.985 - Mlig455_037833 {REF} {Length: 515} {NoTransDecoderORF} {RNA1509_5787} {RNA1310_81873.2} {RNA815_41075}
10. MligTC455_19355 1316 27.42 Mlig455_028094, Mlig455_045219

Neo: -

Age: -

EEPD1 0.97 - - - - 0.970 -

Mlig455_028094 {REF} {Length: 4146} {TRANSSPLICED} {Pfam: Helix-hairpin-helix motif [PF12836.9, score=91.0]; Helix-hairpin-helix motif [PF00633.25, score=45.7]; Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=27.7]; Helix-hairpin-helix domain [PF14520.8, score=23.8]; Type II secretion system (T2SS), protein K [PF03934.15, score=21.9]; Helix-hairpin-helix motif [PF14579.8, score=20.4]; Transposase IS116/IS110/IS902 family [PF02371.18, score=19.1]} {Human: ENSG00000122547, EEPD1, endonuclease/exonuclease/phosphatase family domain containing 1, [RH, Score=338, Expect=4e-108]} {Mouse: ENSMUSG00000036611, Eepd1, endonuclease/exonuclease/phosphatase family domain containing 1, [RH, Score=327, Expect=4e-104]} {Smed: dd_Smed_v6_15723_0_1, dd_Smed_v6_15723_0_1, [RH, Score=214, Expect=9e-64]} {RNA1509_19761, RNA1509_28792, RNA1509_54509, RNA1509_7474} {RNA1310_12271.1, RNA1509_19761, RNA1509_28792, RNA1509_54509} {RNA1509_19761, RNA1509_28792, RNA1509_54509, RNA815_19714}

Mlig455_045219 {REF} {Length: 3893} {TRANSSPLICED} {Pfam: Helix-hairpin-helix motif [PF12836.9, score=91.0]; Helix-hairpin-helix motif [PF00633.25, score=45.7]; Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=26.6]; Helix-hairpin-helix domain [PF14520.8, score=23.9]; Type II secretion system (T2SS), protein K [PF03934.15, score=21.9]; Helix-hairpin-helix motif [PF14579.8, score=20.4]; Transposase IS116/IS110/IS902 family [PF02371.18, score=19.2]} {Human: ENSG00000122547, EEPD1, endonuclease/exonuclease/phosphatase family domain containing 1, [RH, Score=338, Expect=4e-108]} {Mouse: ENSMUSG00000036611, Eepd1, endonuclease/exonuclease/phosphatase family domain containing 1, [RH, Score=327, Expect=5e-104]} {Smed: dd_Smed_v6_15723_0_1, dd_Smed_v6_15723_0_1, [RH, Score=213, Expect=3e-63]} {RNA1509_7474} {RNA1310_12271.1, RNA1509_7474} {RNA1509_7474, RNA815_19714}
11. MligTC455_23931 20507 427.22 Mlig455_069319

Neo: Germline

Age: logFC(26M/2M)=0.468

Region-enriched R5: 3.259/0.00227

0.967 - - - - 0.967 - Mlig455_069319 {REF} {Length: 2278} {Pfam: Immunoglobulin domain [PF13927.8, score=47.4]; Immunoglobulin I-set domain [PF07679.18, score=43.5]; Immunoglobulin domain [PF13895.8, score=34.1]; Immunoglobulin domain [PF00047.27, score=28.5]; Immunoglobulin V-set domain [PF07686.19, score=28.4]} {Smed: dd_Smed_v6_2673_0_1, dd_Smed_v6_2673_0_1, [Score=63.9, Expect=2e-10]} {RNA1509_15245, RNA1509_3600, RNA1509_390, RNA1509_42, RNA1509_43026, RNA1509_95} {RNA1310_10769, RNA1509_15245, RNA1509_3600, RNA1509_390, RNA1509_42, RNA1509_43026, RNA1509_95} {RNA1509_15245, RNA1509_3600, RNA1509_390, RNA1509_42, RNA1509_43026, RNA1509_95, RNA815_3639}
12. Mlig999008.1 0.965 - - - - 0.965 -
13. MligTC455_45422 394 8.22 Mlig455_016167

Neo: -

Age: -

0.964 - - - - 0.964 - Mlig455_016167 {REF} {Length: 1340} {NoTransDecoderORF} {RNA1509_54676} {RNA1310_31510} {RNA815_23806.1}
14. MligTC455_15869 427 8.89 Mlig455_027472

Neo: -

Age: -

Region-enriched R2: 2.299/0.01311

GIPC1 0.961 - - - - 0.961 - Mlig455_027472 {REF} {Length: 4303} {Pfam: PDZ domain [PF00595.26, score=30.8]; PDZ domain [PF17820.3, score=20.8]} {Human: ENSG00000123159, GIPC1, GIPC PDZ domain containing family member 1, [RH, Score=271, Expect=3e-91]} {Mouse: ENSMUSG00000019433, Gipc1, GIPC PDZ domain containing family, member 1, [Score=276, Expect=3e-92]} {Dmel: FBgn0010504, kermit, [Score=290, Expect=2e-97]} {Celegans: WBGene00016440, gipc-1, GIPC (RGS-GAIP Interacting Protein C) homolog, [Score=176, Expect=3e-53]} {Smed: dd_Smed_v6_5847_0_2, dd_Smed_v6_5847_0_2, [Score=277, Expect=9e-93]} {RNA1509_59243} {RNA1310_35154.1} {RNA815_10174.1}
15. MligTC455_35311 284 5.92 Mlig455_030358

Neo: Irradiation

Age: Down-Up-Up, logFC(26M/2M)=0.245

NUP50 0.961 - - - - 0.961 - Mlig455_030358 {REF} {Length: 2323} {TRANSSPLICED} {Pfam: NUP50 (Nucleoporin 50 kDa) [PF08911.13, score=63.2]; RanBP1 domain [PF00638.20, score=43.4]} {Human: ENSG00000093000, NUP50, nucleoporin 50, [RH, Score=198, Expect=2e-57]} {Mouse: ENSMUSG00000016619, Nup50, nucleoporin 50, [RH, Score=102, Expect=5e-23]} {Dmel: FBgn0033264, Nup50, Nucleoporin 50kD, [RH, Score=174, Expect=6e-48]} {Smed: dd_Smed_v6_5140_0_1, dd_Smed_v6_5140_0_1, [RH, Score=175, Expect=4e-50]} {RNA1509_25929, RNA1509_9756} {RNA1310_9766, RNA1509_25929, RNA1509_9756} {RNA1509_25929, RNA1509_9756, RNA815_6757}
16. MligTC455_40102 445 9.27 Mlig455_036637

Neo: -

Age: -

PTPN1 0.961 - - - - 0.961 - Mlig455_036637 {REF} {Length: 4673} {TRANSSPLICED} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=198.0]} {Human: ENSG00000196396, PTPN1, protein tyrosine phosphatase, non-receptor type 1, [RH, Score=257, Expect=3e-76]} {Mouse: ENSMUSG00000027540, Ptpn1, protein tyrosine phosphatase, non-receptor type 1, [RH, Score=258, Expect=6e-77]} {Dmel: FBgn0267487, Ptp61F, Protein tyrosine phosphatase 61F, [RH, Score=235, Expect=2e-67]} {Celegans: WBGene00009717, dep-1, Receptor-type tyrosine-protein phosphatase dep-1, [Score=150, Expect=5e-39]} {Smed: dd_Smed_v6_5710_0_1, dd_Smed_v6_5710_0_1, [RH, Score=233, Expect=1e-67]} {RNA1509_6521} {RNA1310_3969.1} {RNA815_4069}
17. MligTC455_09637 94 1.95 Mlig455_068836

Neo: -

Age: -

Region-enriched R4: 7.544/0.00021

0.959 - - - - 0.959 - Mlig455_068836 {REF} {Length: 248} {NoTransDecoderORF} {RNA1310_39046} {RNA815_41302}
18. MligTC455_26210 473 9.86 Mlig455_069985

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.394

0.958 - - - - 0.958 - Mlig455_069985 {REF} {Length: 3344} {Pfam: P21-Rho-binding domain [PF00786.30, score=33.2]} {RNA1509_9659} {RNA1310_11243.1} {RNA815_9336}
19. MligTC455_53295 119 2.48 Mlig455_060263

Neo: -

Age: -

LMO4 0.957 - - - - 0.957 - Mlig455_060263 {REF} {Length: 1717} {Pfam: LIM domain [PF00412.24, score=87.3]} {Human: ENSG00000143013, LMO4, LIM domain only 4, [Score=133, Expect=9e-39]} {Mouse: ENSMUSG00000028266, Lmo4, LIM domain only 4, [Score=133, Expect=6e-39]} {Dmel: FBgn0032196, CG5708, [Score=120, Expect=4e-33]} {Celegans: WBGene00002987, lim-4, LIM domain family; Putative transcription factor LIM-4, [Score=75.5, Expect=9e-16]} {Smed: dd_Smed_v6_27625_0_1, dd_Smed_v6_27625_0_1, [RH, Score=108, Expect=1e-28]} {RNA1509_53632} {RNA1310_25695, RNA1509_53632} {RNA1509_53632, RNA815_42113}
20. MligTC455_41268 4110 85.63 Mlig455_033606, Mlig455_033710, Mlig455_050119

Neo: Neoblast

Age: Down-Up-Up, logFC(26M/2M)=0.461

Region-enriched R5: 1.223/0.01569

POLR2K 0.956 - - - - 0.956 -

Mlig455_033606 {REF} {Length: 466} {TRANSSPLICED} {Pfam: DNA directed RNA polymerase, 7 kDa subunit [PF03604.15, score=60.8]} {Human: ENSG00000147669, POLR2K, RNA polymerase II subunit K, [RH, Score=81.3, Expect=3e-22]} {Mouse: ENSMUSG00000045996, Polr2k, polymerase (RNA) II (DNA directed) polypeptide K, [RH, Score=83.2, Expect=1e-22]} {Dmel: FBgn0262954, Rpb12, [RH, Score=71.6, Expect=1e-18]} {Celegans: WBGene00009078, rpb-12, RNA Polymerase II (B) subunit, [RH, Score=74.7, Expect=6e-20]} {Smed: dd_Smed_v6_2720_0_1, dd_Smed_v6_2720_0_1, [RH, Score=60.1, Expect=3e-14]} {RNA1509_11039, RNA1509_27812, RNA1509_42819} {RNA1310_75076, RNA1509_27812, RNA1509_42819} {RNA1509_27812, RNA1509_42819, RNA815_39709}

Mlig455_033710 {REF} {Length: 465} {TRANSSPLICED} {Pfam: DNA directed RNA polymerase, 7 kDa subunit [PF03604.15, score=60.8]} {Human: ENSG00000147669, POLR2K, RNA polymerase II subunit K, [RH, Score=81.3, Expect=3e-22]} {Mouse: ENSMUSG00000045996, Polr2k, polymerase (RNA) II (DNA directed) polypeptide K, [RH, Score=83.2, Expect=1e-22]} {Dmel: FBgn0262954, Rpb12, [RH, Score=71.6, Expect=1e-18]} {Celegans: WBGene00009078, rpb-12, RNA Polymerase II (B) subunit, [RH, Score=74.7, Expect=6e-20]} {Smed: dd_Smed_v6_2720_0_1, dd_Smed_v6_2720_0_1, [RH, Score=60.1, Expect=3e-14]} {RNA1509_11039, RNA1509_46032} {RNA1310_75076, RNA1509_11039, RNA1509_46032} {RNA1509_11039, RNA1509_46032, RNA815_39709}

Mlig455_050119 {REF} {Length: 462} {TRANSSPLICED} {Pfam: DNA directed RNA polymerase, 7 kDa subunit [PF03604.15, score=60.8]} {Human: ENSG00000147669, POLR2K, RNA polymerase II subunit K, [RH, Score=81.3, Expect=3e-22]} {Mouse: ENSMUSG00000045996, Polr2k, polymerase (RNA) II (DNA directed) polypeptide K, [RH, Score=83.2, Expect=1e-22]} {Dmel: FBgn0262954, Rpb12, [RH, Score=71.6, Expect=1e-18]} {Celegans: WBGene00009078, rpb-12, RNA Polymerase II (B) subunit, [RH, Score=74.7, Expect=6e-20]} {Smed: dd_Smed_v6_2720_0_1, dd_Smed_v6_2720_0_1, [RH, Score=60.1, Expect=3e-14]} {RNA1509_11039} {RNA1310_75076} {RNA815_39709}
21. MligTC455_51730 118 2.46 Mlig455_034734

Neo: Int S/G2/M

Age: -

0.956 - - - - 0.956 - Mlig455_034734 {REF} {Length: 1953} {TRANSSPLICED} {RNA1509_20510} {RNA1310_36557, RNA1509_20510} {RNA1509_20510, RNA815_29917}
22. MligTC455_33518 74 1.54 Mlig455_034081

Neo: -

Age: -

SLC5A9 0.955 - - - - 0.955 - Mlig455_034081 {REF} {Length: 2394} {Pfam: Sodium:solute symporter family [PF00474.19, score=357.0]} {Human: ENSG00000117834, SLC5A9, solute carrier family 5 member 9, [RH, Score=545, Expect=0.0]} {Mouse: ENSMUSG00000028544, Slc5a9, solute carrier family 5 (sodium/glucose cotransporter), member 9, [Score=556, Expect=0.0]} {Dmel: FBgn0039872, salt, salty dog, [Score=85.1, Expect=8e-17]} {Smed: dd_Smed_v6_6663_0_1, dd_Smed_v6_6663_0_1, [Score=506, Expect=7e-172]} {RNA1509_13834} {RNA1310_9462} {RNA815_5775}
23. MligTC455_29999 423 8.81 Mlig455_031441

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.637

Region-enriched R4: 5.833/0.02124

0.954 - - - - 0.954 - Mlig455_031441 {REF} {Length: 1354} {NoTransDecoderORF} {RNA1509_31776} {RNA1310_7321.1} {RNA815_4667}
24. MligTC455_39964 112 2.33 Mlig455_023603

Neo: -

Age: -

DHX16 0.954 - - - - 0.954 - Mlig455_023603 {REF} {Length: 3761} {TRANSSPLICED} {Pfam: Helicase associated domain (HA2) [PF04408.25, score=77.5]; Oligonucleotide/oligosaccharide-binding (OB)-fold [PF07717.18, score=64.2]; Helicase conserved C-terminal domain [PF00271.33, score=45.2]; DEAD/DEAH box helicase [PF00270.31, score=24.8]; AAA domain [PF13401.8, score=21.4]; AAA domain [PF13604.8, score=18.9]} {Human: ENSG00000226171, DHX16, DEAH-box helicase 16, [RH, Score=1186, Expect=0.0]; ENSG00000204560, DHX16, DEAH-box helicase 16, [RH, Score=1186, Expect=0.0]; ENSG00000233049, DHX16, DEAH-box helicase 16, [RH, Score=1186, Expect=0.0]; ENSG00000233561, DHX16, DEAH-box helicase 16, [RH, Score=1186, Expect=0.0]; ENSG00000231377, DHX16, DEAH-box helicase 16, [RH, Score=1186, Expect=0.0]; ENSG00000233418, DHX16, DEAH-box helicase 16, [RH, Score=1186, Expect=0.0]; ENSG00000206486, DHX16, DEAH-box helicase 16, [RH, Score=1183, Expect=0.0]} {Mouse: ENSMUSG00000024422, Dhx16, DEAH (Asp-Glu-Ala-His) box polypeptide 16, [RH, Score=1190, Expect=0.0]} {Dmel: FBgn0086444, l(2)37Cb, lethal (2) 37Cb, [RH, Score=1229, Expect=0.0]} {Celegans: WBGene00003392, mog-4, Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4, [RH, Score=1166, Expect=0.0]} {Smed: dd_Smed_v6_10434_0_1, dd_Smed_v6_10434_0_1, [RH, Score=885, Expect=0.0]} {RNA1509_6379} {RNA1310_4272} {RNA815_1313}
25. MligTC455_09772 568 11.83 Mlig455_007711

Neo: -

Age: -

0.953 - - - - 0.953 - Mlig455_007711 {REF} {Length: 762} {Pfam: RNase H [PF00075.26, score=32.9]; zinc-binding in reverse transcriptase [PF13966.8, score=20.5]} {RNA1509_42121} {RNA1310_28357.1} {RNA815_28691}
26. MligTC455_11565 693 14.44 Mlig455_068964

Neo: -

Age: -

TSTA3 0.953 - - - - 0.953 - Mlig455_068964 {REF} {Length: 1823} {TRANSSPLICED} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=176.5]; GDP-mannose 4,6 dehydratase [PF16363.7, score=48.0]; RmlD substrate binding domain [PF04321.19, score=29.5]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=25.0]} {Human: ENSG00000278243, TSTA3, tissue specific transplantation antigen P35B, [RH, Score=448, Expect=6e-159]; ENSG00000104522, TSTA3, tissue specific transplantation antigen P35B, [RH, Score=448, Expect=6e-159]} {Mouse: ENSMUSG00000022570, Tsta3, tissue specific transplantation antigen P35B, [RH, Score=447, Expect=1e-158]} {Dmel: FBgn0267823, Gmer, GDP-4-keto-6-deoxy-D-mannose 3,5-epimerase/4-reductase, [RH, Score=384, Expect=5e-134]} {Celegans: WBGene00019813, ger-1, GDP-L-fucose synthase, [RH, Score=428, Expect=8e-152]} {Smed: dd_Smed_v6_5072_0_1, dd_Smed_v6_5072_0_1, [RH, Score=424, Expect=3e-150]} {RNA1509_16631} {RNA1310_30944} {RNA815_14098}
27. MligTC455_18427 453 9.43 Mlig455_051696

Neo: -

Age: Down-Up-Up

PLGRKT 0.953 - - - - 0.953 - Mlig455_051696 {REF} {Length: 1122} {TRANSSPLICED} {Pfam: Uncharacterised conserved protein (DUF2368) [PF10166.11, score=158.4]} {Human: ENSG00000107020, PLGRKT, plasminogen receptor with a C-terminal lysine, [RH, Score=103, Expect=8e-29]} {Mouse: ENSMUSG00000016495, Plgrkt, plasminogen receptor, C-terminal lysine transmembrane protein, [RH, Score=107, Expect=4e-30]} {Celegans: WBGene00044322, tag-280, [Score=43.9, Expect=4e-06]} {RNA1509_19636} {RNA1310_48798} {RNA815_29796}
28. MligTC455_30950 282 5.87 Mlig455_008403

Neo: -

Age: Down-Up-Down

Region-enriched R5: 1.890/0.00007

0.953 - - - - 0.953 - Mlig455_008403 {REF} {Length: 1659} {Pfam: Cupin superfamily (DUF985) [PF06172.13, score=102.7]} {RNA1509_57035} {RNA1310_31259, RNA1509_57035} {RNA1509_57035, RNA815_14348}
29. MligTC455_36640 176 3.67 Mlig455_049018

Neo: -

Age: -

0.953 - - - - 0.953 - Mlig455_049018 {REF} {Length: 720} {NoTransDecoderORF} {RNA1509_26249} {RNA1310_28755, RNA1509_26249} {RNA1509_26249, RNA815_29837.2}
30. MligTC455_43403 347 7.22 Mlig455_015913, Mlig455_059672

Neo: -

Age: Down-Up-Down

0.953 - - - - 0.953 -

Mlig455_015913 {REF} {Length: 2147} {NoTransDecoderORF} {RNA1509_4496} {RNA1310_3148.1} {RNA815_3879}

Mlig455_059672 {REF} {Length: 746} {NoTransDecoderORF} {RNA1509_42088, RNA1509_4496} {RNA1310_3148.1, RNA1509_42088} {RNA1509_42088, RNA815_3879}
31. MligTC455_43090 224 4.67 Mlig455_012693

Neo: -

Age: Up-Down-Up

SPAST 0.952 - - - - 0.952 - Mlig455_012693 {REF} {Length: 4302} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=127.2]; AAA+ lid domain [PF17862.3, score=38.6]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=25.4]; AAA domain [PF13401.8, score=21.9]; TIP49 P-loop domain [PF06068.15, score=20.6]; IstB-like ATP binding protein [PF01695.19, score=20.2]; Bacterial TniB protein [PF05621.13, score=18.5]} {Human: ENSG00000021574, SPAST, spastin, [RH, Score=345, Expect=6e-114]} {Mouse: ENSMUSG00000024068, Spast, spastin, [RH, Score=342, Expect=9e-112]} {Dmel: FBgn0039141, spas, spastin, [RH, Score=328, Expect=2e-105]} {Celegans: WBGene00016045, spas-1, Probable spastin homolog spas-1, [RH, Score=303, Expect=1e-98]} {Smed: dd_Smed_v6_7472_0_1, dd_Smed_v6_7472_0_1, [RH, Score=322, Expect=1e-104]} {RNA1509_45741, RNA1509_60086} {RNA1310_17702, RNA1509_45741} {RNA1509_45741, RNA815_24923}
32. MligTC455_44425 460 9.58 Mlig455_041704

Neo: -

Age: -

IPO11 0.952 - - - - 0.952 - Mlig455_041704 {REF} {Length: 4130} {TRANSSPLICED} {Pfam: Importin-beta N-terminal domain [PF03810.21, score=40.5]} {Human: ENSG00000086200, IPO11, importin 11, [RH, Score=132, Expect=1e-30]} {Mouse: ENSMUSG00000042590, Ipo11, importin 11, [RH, Score=132, Expect=5e-31]} {Dmel: FBgn0284254, Impbeta11, Importin beta11, [RH, Score=96.7, Expect=5e-20]} {RNA1509_12338} {RNA1310_4949.1} {RNA815_1982}
33. MligTC455_49497 210 4.38 Mlig455_034328

Neo: -

Age: -

ARMT1 0.952 - - - - 0.952 - Mlig455_034328 {REF} {Length: 7345} {Pfam: Damage-control phosphatase ARMT1-like domain [PF01937.21, score=267.7]} {Human: ENSG00000146476, ARMT1, acidic residue methyltransferase 1, [RH, Score=222, Expect=3e-67]} {Mouse: ENSMUSG00000061759, Armt1, acidic residue methyltransferase 1, [RH, Score=219, Expect=2e-66]} {Dmel: FBgn0034689, CG2921, [Score=201, Expect=5e-59]} {Celegans: WBGene00009290, F31D4.2, [RH, Score=194, Expect=8e-57]} {Smed: dd_Smed_v6_11241_0_1, dd_Smed_v6_11241_0_1, [Score=181, Expect=5e-52]} {RNA1509_35866} {RNA1310_20337.1, RNA1509_35866} {RNA1509_35866, RNA815_24582}
34. MligTC455_39126 319 6.64 Mlig455_039302, Mlig455_054473, Mlig455_068598

Neo: -

Age: Up-Down-Down

GIPC1 0.951 - - - - 0.951 -

Mlig455_039302 {REF} {Length: 3377} {Pfam: PDZ domain [PF00595.26, score=33.4]; PDZ domain [PF17820.3, score=18.9]} {Human: ENSG00000123159, GIPC1, GIPC PDZ domain containing family member 1, [Score=281, Expect=2e-93]} {Mouse: ENSMUSG00000019433, Gipc1, GIPC PDZ domain containing family, member 1, [Score=283, Expect=3e-94]} {Dmel: FBgn0010504, kermit, [Score=300, Expect=6e-101]} {Celegans: WBGene00016440, gipc-1, GIPC (RGS-GAIP Interacting Protein C) homolog, [Score=182, Expect=6e-55]} {Smed: dd_Smed_v6_5847_0_2, dd_Smed_v6_5847_0_2, [Score=280, Expect=3e-93]} {RNA1509_30159} {RNA1310_22067} {RNA815_21783}

Mlig455_054473 {REF} {Length: 262} {NoTransDecoderORF} {RNA1509_30159} {RNA1310_22067} {RNA815_20472}

Mlig455_068598 {REF} {Length: 984} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=21.4]} {RNA1509_49822} {RNA1310_49394} {RNA815_51942}
35. MligTC455_48877 414 8.63 Mlig455_064220

Neo: -

Age: -

CACNB4 0.951 - - - - 0.951 - Mlig455_064220 {REF} {Length: 3341} {Pfam: Guanylate kinase [PF00625.23, score=139.2]; Voltage gated calcium channel subunit beta domain 4Aa N terminal [PF12052.10, score=24.3]} {Human: ENSG00000182389, CACNB4, calcium voltage-gated channel auxiliary subunit beta 4, [RH, Score=318, Expect=1e-103]} {Mouse: ENSMUSG00000020882, Cacnb1, calcium channel, voltage-dependent, beta 1 subunit, [Score=325, Expect=2e-104]; ENSMUSG00000057914, Cacnb2, calcium channel, voltage-dependent, beta 2 subunit, [Score=322, Expect=1e-101]; ENSMUSG00000017412, Cacnb4, calcium channel, voltage-dependent, beta 4 subunit, [Score=318, Expect=2e-101]; ENSMUSG00000003352, Cacnb3, calcium channel, voltage-dependent, beta 3 subunit, [Score=315, Expect=2e-100]} {Dmel: FBgn0259822, Ca-beta, Ca2+-channel-protein-beta-subunit, [Score=332, Expect=7e-108]} {Celegans: WBGene00000368, ccb-1, Calcium Channel, Beta subunit, [Score=328, Expect=4e-105]} {Smed: dd_Smed_v6_9267_0_1, dd_Smed_v6_9267_0_1, [Score=342, Expect=3e-110]} {RNA1509_13952} {RNA1310_9640} {RNA815_20879}
36. MligTC455_50966 248 5.17 Mlig455_034883, Mlig455_034896

Neo: -

Age: Down-Up-Up

NOL12 0.951 - - - - 0.951 -

Mlig455_034883 {REF} {Length: 672} {TRANSSPLICED} {Pfam: Nucleolar protein 12 (25kDa) [PF09805.11, score=44.6]} {Human: ENSG00000273899, NOL12, nucleolar protein 12, [RH, Score=59.7, Expect=3e-11]; ENSG00000100101, Z83844.1, novel transcript, [RH, Score=59.7, Expect=3e-11]} {Mouse: ENSMUSG00000033099, Nol12, nucleolar protein 12, [RH, Score=57.8, Expect=1e-10]} {RNA1509_42821} {RNA1310_81032} {RNA815_24269}

Mlig455_034896 {REF} {Length: 709} {TRANSSPLICED} {Pfam: Nucleolar protein 12 (25kDa) [PF09805.11, score=50.1]} {Human: ENSG00000273899, NOL12, nucleolar protein 12, [RH, Score=62.0, Expect=8e-12]; ENSG00000100101, Z83844.1, novel transcript, [RH, Score=61.6, Expect=1e-11]} {Mouse: ENSMUSG00000033099, Nol12, nucleolar protein 12, [RH, Score=59.7, Expect=4e-11]} {RNA1509_42821} {RNA1310_51251, RNA1509_42821} {RNA1509_42821, RNA815_24269}
37. MligTC455_51799 156 3.26 Mlig455_036197

Neo: -

Age: Down-Up-Up

0.951 - - - - 0.951 - Mlig455_036197 {REF} {Length: 1727} {TRANSSPLICED} {Pfam: Polyketide synthase dehydratase [PF14765.8, score=18.9]} {RNA1509_21448} {RNA1310_31836} {RNA815_14455}
38. MligTC455_25929 599 12.47 Mlig455_008569

Neo: -

Age: -

GMPPB 0.95 - - - - 0.950 - Mlig455_008569 {REF} {Length: 4414} {TRANSSPLICED} {Pfam: Nucleotidyl transferase [PF00483.25, score=72.9]; Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=48.2]; Hexapeptide repeat of succinyl-transferase [PF14602.8, score=20.3]} {Human: ENSG00000173540, GMPPB, GDP-mannose pyrophosphorylase B, [Score=333, Expect=2e-114]} {Mouse: ENSMUSG00000070284, Gmppb, GDP-mannose pyrophosphorylase B, [Score=332, Expect=2e-114]} {Dmel: FBgn0037279, CG1129, [Score=330, Expect=2e-113]} {Celegans: WBGene00016583, tag-335, Mannose-1-phosphate guanyltransferase beta, [Score=303, Expect=6e-103]} {Smed: dd_Smed_v6_3771_0_1, dd_Smed_v6_3771_0_1, [Score=301, Expect=2e-102]} {RNA1509_16866, RNA1509_44160} {RNA1310_26477, RNA1509_16866, RNA1509_44160} {RNA1509_16866, RNA1509_44160, RNA815_6990.1}
39. MligTC455_50235 1163 24.24 Mlig455_007111, Mlig455_007151

Neo: -

Age: logFC(26M/2M)=-0.340

SLC6A5 0.95 - - - - 0.950 -

Mlig455_007111 {REF} {Length: 6163} {TRANSSPLICED} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=618.5]; Dynactin subunit p22 [PF07426.13, score=131.2]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=523, Expect=4e-172]; ENSG00000196517, SLC6A9, solute carrier family 6 member 9, [Score=501, Expect=2e-165]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=532, Expect=8e-176]} {Dmel: FBgn0034911, CG5549, [Score=492, Expect=5e-156]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=409, Expect=4e-131]} {Smed: dd_Smed_v6_6616_0_1, dd_Smed_v6_6616_0_1, [RH, Score=665, Expect=0.0]} {RNA1509_8801} {RNA1310_5907.1} {RNA815_1736.1}

Mlig455_007151 {REF} {Length: 5461} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=619.2]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=519, Expect=2e-172]; ENSG00000196517, SLC6A9, solute carrier family 6 member 9, [Score=499, Expect=1e-166]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=528, Expect=2e-176]} {Dmel: FBgn0034911, CG5549, [Score=489, Expect=7e-157]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=408, Expect=2e-132]} {Smed: dd_Smed_v6_6616_0_1, dd_Smed_v6_6616_0_1, [RH, Score=661, Expect=0.0]} {RNA1509_8801} {RNA1310_5907.1} {RNA815_1736.1}

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