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Results for MligTC455_23530

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_23530 415 8.65 Mlig455_008839

Neo: -

Age: -

Region-enriched R4: 1.825/0.00569

PYCR2 Mlig455_008839 {REF} {Length: 1240} {TRANSSPLICED} {Pfam: Pyrroline-5-carboxylate reductase dimerisation [PF14748.8, score=131.6]; NADP oxidoreductase coenzyme F420-dependent [PF03807.19, score=80.7]; NAD binding domain of 6-phosphogluconate dehydrogenase [PF03446.17, score=23.7]; Ornithine cyclodeaminase/mu-crystallin family [PF02423.17, score=22.0]; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus [PF01210.25, score=21.8]; Shikimate / quinate 5-dehydrogenase [PF01488.22, score=20.6]; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain [PF02826.21, score=18.4]} {Human: ENSG00000143811, PYCR2, pyrroline-5-carboxylate reductase 2, [RH, Score=237, Expect=1e-76]; ENSG00000183010, PYCR1, pyrroline-5-carboxylate reductase 1, [RH, Score=233, Expect=3e-75]} {Mouse: ENSMUSG00000025140, Pycr1, pyrroline-5-carboxylate reductase 1, [RH, Score=233, Expect=2e-75]; ENSMUSG00000026520, Pycr2, pyrroline-5-carboxylate reductase family, member 2, [RH, Score=230, Expect=3e-74]} {Dmel: FBgn0038516, P5cr-2, Pyrroline-5-carboxylate reductase-like 2, [RH, Score=222, Expect=1e-71]} {Celegans: WBGene00010924, M153.1, [RH, Score=224, Expect=2e-72]} {Smed: dd_Smed_v6_3217_0_2, dd_Smed_v6_3217_0_2, [RH, Score=167, Expect=4e-50]} {RNA1509_5212} {RNA1310_10890} {RNA815_11280.1}

Cumulative graph for MligTC455_23530

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.094 3.684 0.95002 1.00000
RegionR2 -1.574 3.684 0.00965 0.09847
RegionR3 0.207 3.684 0.63865 1.00000
RegionR4 1.825 3.684 0.00047 0.00569
RegionR5 1.029 3.684 0.00921 0.05440
RegionR6 0.214 3.684 0.63820 1.00000
RegionR7 -0.951 3.684 0.17733 0.77206
RegionR8 -0.656 3.684 0.45141 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -6.493 3.684 0.18856 0.92837
RegenerationR2 0.325 3.684 0.48456 0.86518
RegenerationR3 -0.376 3.684 0.42451 0.81806
RegenerationR4 -0.726 3.684 0.12729 0.54151
RegenerationR5 -0.549 3.684 0.19506 0.62675
RegenerationR6 -0.216 3.684 0.64885 0.89782
RegenerationBL -0.846 3.684 0.25655 0.61365
RegenerationTP 0.232 3.684 0.75567 1.00000


Genes with expression patterns similar to MligTC455_23530

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_23530 415 8.65 Mlig455_008839

Neo: -

Age: -

Region-enriched R4: 1.825/0.00569

PYCR2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_008839 {REF} {Length: 1240} {TRANSSPLICED} {Pfam: Pyrroline-5-carboxylate reductase dimerisation [PF14748.8, score=131.6]; NADP oxidoreductase coenzyme F420-dependent [PF03807.19, score=80.7]; NAD binding domain of 6-phosphogluconate dehydrogenase [PF03446.17, score=23.7]; Ornithine cyclodeaminase/mu-crystallin family [PF02423.17, score=22.0]; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus [PF01210.25, score=21.8]; Shikimate / quinate 5-dehydrogenase [PF01488.22, score=20.6]; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain [PF02826.21, score=18.4]} {Human: ENSG00000143811, PYCR2, pyrroline-5-carboxylate reductase 2, [RH, Score=237, Expect=1e-76]; ENSG00000183010, PYCR1, pyrroline-5-carboxylate reductase 1, [RH, Score=233, Expect=3e-75]} {Mouse: ENSMUSG00000025140, Pycr1, pyrroline-5-carboxylate reductase 1, [RH, Score=233, Expect=2e-75]; ENSMUSG00000026520, Pycr2, pyrroline-5-carboxylate reductase family, member 2, [RH, Score=230, Expect=3e-74]} {Dmel: FBgn0038516, P5cr-2, Pyrroline-5-carboxylate reductase-like 2, [RH, Score=222, Expect=1e-71]} {Celegans: WBGene00010924, M153.1, [RH, Score=224, Expect=2e-72]} {Smed: dd_Smed_v6_3217_0_2, dd_Smed_v6_3217_0_2, [RH, Score=167, Expect=4e-50]} {RNA1509_5212} {RNA1310_10890} {RNA815_11280.1}
2. MligTC455_40926 680 14.16 Mlig455_029450, Mlig455_029472

Neo: -

Age: Up-Down-Up

Region-enriched R4: 2.535/0.00634
Region-enriched R3: 2.023/0.02088

OTOF 1.696 - - 0.726 - 0.970 -

Mlig455_029450 {REF} {Length: 7011} {Pfam: C2 domain [PF00168.32, score=238.1]; Ferlin C-terminus [PF16165.7, score=107.1]; FerB (NUC096) domain [PF08150.14, score=73.3]; FerI (NUC094) domain [PF08151.14, score=62.3]} {Human: ENSG00000115155, OTOF, otoferlin, [Score=847, Expect=0.0]} {Mouse: ENSMUSG00000062372, Otof, otoferlin, [Score=845, Expect=0.0]} {Dmel: FBgn0266757, mfr, misfire, [RH, Score=324, Expect=3e-89]} {Celegans: WBGene00001414, fer-1, Sperm vesicle fusion protein fer-1, [Score=145, Expect=3e-34]} {Smed: dd_Smed_v6_5915_0_1, dd_Smed_v6_5915_0_1, [Score=1229, Expect=0.0]} {RNA1509_44062, RNA1509_58476} {RNA1310_427.1, RNA1509_44062} {RNA1509_44062, RNA815_1463}

Mlig455_029472 {REF} {Length: 6996} {Pfam: C2 domain [PF00168.32, score=238.4]; Ferlin C-terminus [PF16165.7, score=107.1]; FerB (NUC096) domain [PF08150.14, score=73.4]; FerI (NUC094) domain [PF08151.14, score=62.3]} {Human: ENSG00000115155, OTOF, otoferlin, [Score=849, Expect=0.0]} {Mouse: ENSMUSG00000062372, Otof, otoferlin, [Score=846, Expect=0.0]} {Dmel: FBgn0266757, mfr, misfire, [RH, Score=324, Expect=3e-89]} {Celegans: WBGene00001414, fer-1, Sperm vesicle fusion protein fer-1, [Score=145, Expect=3e-34]} {Smed: dd_Smed_v6_5915_0_1, dd_Smed_v6_5915_0_1, [Score=1231, Expect=0.0]} {RNA1509_58476} {RNA1310_427.1, RNA1509_58476} {RNA1509_58476, RNA815_1463}
3. MligTC455_30390 144 3 Mlig455_070663

Neo: -

Age: Up-Down-Down

TRAF6 1.661 - - 0.707 0.954 - - Mlig455_070663 {REF} {Length: 2869} {Pfam: TRAF-type zinc finger [PF02176.20, score=37.7]; WD domain, G-beta repeat [PF00400.34, score=19.6]} {Human: ENSG00000175104, TRAF6, TNF receptor associated factor 6, [Score=92.8, Expect=5e-19]} {Mouse: ENSMUSG00000026942, Traf2, TNF receptor-associated factor 2, [Score=90.1, Expect=2e-18]; ENSMUSG00000021277, Traf3, TNF receptor-associated factor 3, [Score=89.7, Expect=4e-18]; ENSMUSG00000027164, Traf6, TNF receptor-associated factor 6, [Score=87.8, Expect=1e-17]} {Smed: dd_Smed_v6_168_0_1, dd_Smed_v6_168_0_1, [Score=97.1, Expect=4e-21]} {RNA1509_41116} {RNA1310_9652.1, RNA1509_41116} {RNA1509_41116, RNA815_7741}
4. MligTC455_47587 729 15.2 Mlig455_011150, Mlig455_050861

Neo: Int S/G2/M

Age: Down-Up-Up

ZCCHC4 0.965 - - - - 0.965 -

Mlig455_011150 {REF} {Length: 1311} {TRANSSPLICED} {RNA1509_54245} {RNA1310_22852} {RNA815_47398}

Mlig455_050861 {REF} {Length: 1298} {TRANSSPLICED} {Pfam: Probable N6-adenine methyltransferase [PF10237.11, score=51.7]} {Human: ENSG00000168228, ZCCHC4, zinc finger CCHC-type containing 4, [RH, Score=145, Expect=4e-38]} {Mouse: ENSMUSG00000029179, Zcchc4, zinc finger, CCHC domain containing 4, [RH, Score=144, Expect=3e-38]} {Dmel: FBgn0033948, CG12863, [RH, Score=115, Expect=2e-28]} {Celegans: WBGene00009352, F33A8.4, [RH, Score=129, Expect=3e-33]} {Smed: dd_Smed_v6_11308_0_1, dd_Smed_v6_11308_0_1, [RH, Score=167, Expect=4e-48]} {RNA1509_54245} {RNA1310_22852, RNA1509_54245} {RNA1509_54245, RNA815_47398}
5. MligTC455_33379 73 1.53 Mlig455_048175

Neo: -

Age: -

PDSS1 0.957 - - - - - 0.957 Mlig455_048175 {REF} {Length: 1712} {TRANSSPLICED} {Pfam: Polyprenyl synthetase [PF00348.19, score=196.4]} {Human: ENSG00000148459, PDSS1, decaprenyl diphosphate synthase subunit 1, [RH, Score=229, Expect=4e-71]} {Mouse: ENSMUSG00000026784, Pdss1, prenyl (solanesyl) diphosphate synthase, subunit 1, [RH, Score=226, Expect=3e-70]} {Dmel: FBgn0051005, qless, [RH, Score=235, Expect=9e-74]} {Celegans: WBGene00000761, coq-1, COenzyme Q (Ubiquinone) biosynthesis, [RH, Score=211, Expect=3e-65]} {Smed: dd_Smed_v6_12221_0_1, dd_Smed_v6_12221_0_1, [RH, Score=252, Expect=3e-81]} {RNA1509_18613} {RNA1310_15422} {RNA815_6758.1}
6. MligTC455_45375 245 5.1 Mlig455_009938

Neo: -

Age: -

PFKFB1 0.955 - - - - - 0.955 Mlig455_009938 {REF} {Length: 2838} {Pfam: 6-phosphofructo-2-kinase [PF01591.20, score=288.2]; Histidine phosphatase superfamily (branch 1) [PF00300.24, score=129.5]; AAA domain [PF13671.8, score=26.0]} {Human: ENSG00000158571, PFKFB1, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1, [RH, Score=524, Expect=0.0]; ENSG00000123836, PFKFB2, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2, [RH, Score=509, Expect=1e-176]; ENSG00000114268, PFKFB4, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, [RH, Score=504, Expect=3e-175]; ENSG00000170525, PFKFB3, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, [RH, Score=498, Expect=2e-172]} {Mouse: ENSMUSG00000025271, Pfkfb1, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1, [RH, Score=523, Expect=0.0]; ENSMUSG00000026773, Pfkfb3, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, [RH, Score=506, Expect=2e-176]; ENSMUSG00000025648, Pfkfb4, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, [RH, Score=505, Expect=5e-176]; ENSMUSG00000026409, Pfkfb2, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2, [RH, Score=502, Expect=1e-174]} {Dmel: FBgn0027621, Pfrx, 6-phosphofructo-2-kinase, [RH, Score=484, Expect=2e-164]} {Celegans: WBGene00022456, pfkb-1.1, [RH, Score=455, Expect=4e-157]} {Smed: dd_Smed_v6_3959_0_1, dd_Smed_v6_3959_0_1, [RH, Score=534, Expect=0.0]} {RNA1509_14561, RNA1509_15746} {RNA1310_8036.1, RNA1509_14561, RNA1509_15746} {RNA1509_14561, RNA1509_15746, RNA815_2585.1}
7. MligTC455_48741 595 12.4 Mlig455_030441

Neo: -

Age: logFC(26M/2M)=0.386

Region-enriched R3: 1.628/0.00011

CAMK1G 0.953 - - - - 0.953 - Mlig455_030441 {REF} {Length: 3661} {Pfam: Protein kinase domain [PF00069.27, score=99.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=74.8]} {Human: ENSG00000008118, CAMK1G, calcium/calmodulin dependent protein kinase IG, [Score=76.6, Expect=8e-14]; ENSG00000185974, GRK1, G protein-coupled receptor kinase 1, [Score=72.8, Expect=1e-12]; ENSG00000104365, IKBKB, inhibitor of nuclear factor kappa B kinase subunit beta, [Score=72.8, Expect=2e-12]} {Mouse: ENSMUSG00000016179, Camk1g, calcium/calmodulin-dependent protein kinase I gamma, [Score=76.6, Expect=2e-14]; ENSMUSG00000073458, Smok2a, sperm motility kinase 2A, [Score=75.9, Expect=1e-13]; ENSMUSG00000031450, Grk1, G protein-coupled receptor kinase 1, [Score=74.7, Expect=3e-13]} {Dmel: FBgn0003079, Raf, Raf oncogene, [Score=71.6, Expect=2e-12]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=73.9, Expect=5e-13]} {Smed: dd_Smed_v6_9065_0_1, dd_Smed_v6_9065_0_1, [Score=80.1, Expect=4e-16]} {RNA1509_12915} {RNA1310_2128, RNA1509_12915} {RNA1509_12915, RNA815_5571}
8. MligTC455_53375 8041 167.51 Mlig455_021776, Mlig455_050833

Neo: -

Age: logFC(26M/2M)=-0.280

GLO1 0.952 - - - 0.952 - -

Mlig455_021776 {REF} {Length: 897} {TRANSSPLICED} {Pfam: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily [PF00903.27, score=84.9]; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily [PF13669.8, score=30.3]; Glyoxalase-like domain [PF18029.3, score=20.0]} {Human: ENSG00000124767, GLO1, glyoxalase I, [RH, Score=236, Expect=6e-80]} {Mouse: ENSMUSG00000024026, Glo1, glyoxalase 1, [RH, Score=243, Expect=2e-82]} {Dmel: FBgn0283450, Glo1, Glyoxalase 1, [RH, Score=226, Expect=2e-76]} {RNA1509_22893, RNA1509_32272} {RNA1310_31766, RNA1509_22893, RNA1509_32272} {RNA1509_22893, RNA1509_32272, RNA815_19966}

Mlig455_050833 {REF} {Length: 893} {TRANSSPLICED} {Pfam: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily [PF00903.27, score=84.9]; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily [PF13669.8, score=30.3]; Glyoxalase-like domain [PF18029.3, score=20.0]} {Human: ENSG00000124767, GLO1, glyoxalase I, [RH, Score=236, Expect=6e-80]} {Mouse: ENSMUSG00000024026, Glo1, glyoxalase 1, [RH, Score=243, Expect=2e-82]} {Dmel: FBgn0283450, Glo1, Glyoxalase 1, [RH, Score=226, Expect=2e-76]} {RNA1509_32272} {RNA1310_31766} {RNA815_19966}
9. MligTC455_03889 198 4.12 Mlig455_011519

Neo: Int S/G2/M

Age: -

Region-enriched R5: 2.193/0.00342

0.95 - - - - - 0.950 Mlig455_011519 {REF} {Length: 1539} {RNA1509_29174} {RNA1310_34623} {RNA815_15967}

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