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Results for MligTC455_24867

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_24867 495 10.32 Mlig455_063618

Neo: -

Age: Up-Down-Down

ERN1 Mlig455_063618 {REF} {Length: 6642} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=122.6]; Ribonuclease 2-5A [PF06479.14, score=110.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=70.7]; PQQ-like domain [PF13360.8, score=26.8]; Fungal protein kinase [PF17667.3, score=25.4]; PQQ enzyme repeat [PF01011.23, score=21.1]} {Human: ENSG00000178607, ERN1, endoplasmic reticulum to nucleus signaling 1, [Score=400, Expect=1e-119]} {Mouse: ENSMUSG00000020715, Ern1, endoplasmic reticulum (ER) to nucleus signalling 1, [RH, Score=408, Expect=1e-122]} {Dmel: FBgn0261984, Ire1, Inositol-requiring enzyme-1, [RH, Score=471, Expect=1e-144]} {Celegans: WBGene00002147, ire-1, Serine/threonine-protein kinase/endoribonuclease ire-1 Serine/threonine-protein kinase Endoribonuclease, [RH, Score=498, Expect=3e-156]} {Smed: dd_Smed_v6_9184_0_1, dd_Smed_v6_9184_0_1, [RH, Score=300, Expect=1e-85]} {RNA1509_4866} {RNA1310_1666.1, RNA1509_4866} {RNA1509_4866, RNA815_330}

Cumulative graph for MligTC455_24867

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.297 3.707 0.78017 1.00000
RegionR2 0.574 3.707 0.27221 0.65681
RegionR3 0.027 3.707 0.95110 1.00000
RegionR4 -0.05 3.707 0.92206 1.00000
RegionR5 -0.381 3.707 0.35663 0.70770
RegionR6 -0.49 3.707 0.29234 0.88379
RegionR7 0.297 3.707 0.57903 1.00000
RegionR8 -0.273 3.707 0.69043 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.866 3.707 0.60696 1.00000
RegenerationR2 0.488 3.707 0.28092 0.72479
RegenerationR3 0.38 3.707 0.46431 0.84068
RegenerationR4 0.004 3.707 0.99332 1.00000
RegenerationR5 0.232 3.707 0.64078 0.92722
RegenerationR6 0.697 3.707 0.20956 0.55262
RegenerationBL -0.347 3.707 0.60826 0.95424
RegenerationTP 0.536 3.707 0.39381 0.82505


Genes with expression patterns similar to MligTC455_24867

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_24867 495 10.32 Mlig455_063618

Neo: -

Age: Up-Down-Down

ERN1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_063618 {REF} {Length: 6642} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=122.6]; Ribonuclease 2-5A [PF06479.14, score=110.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=70.7]; PQQ-like domain [PF13360.8, score=26.8]; Fungal protein kinase [PF17667.3, score=25.4]; PQQ enzyme repeat [PF01011.23, score=21.1]} {Human: ENSG00000178607, ERN1, endoplasmic reticulum to nucleus signaling 1, [Score=400, Expect=1e-119]} {Mouse: ENSMUSG00000020715, Ern1, endoplasmic reticulum (ER) to nucleus signalling 1, [RH, Score=408, Expect=1e-122]} {Dmel: FBgn0261984, Ire1, Inositol-requiring enzyme-1, [RH, Score=471, Expect=1e-144]} {Celegans: WBGene00002147, ire-1, Serine/threonine-protein kinase/endoribonuclease ire-1 Serine/threonine-protein kinase Endoribonuclease, [RH, Score=498, Expect=3e-156]} {Smed: dd_Smed_v6_9184_0_1, dd_Smed_v6_9184_0_1, [RH, Score=300, Expect=1e-85]} {RNA1509_4866} {RNA1310_1666.1, RNA1509_4866} {RNA1509_4866, RNA815_330}
2. MligTC455_47395 71 1.48 Mlig455_052211

Neo: -

Age: -

CHRNA10 1.733 - - 0.782 - 0.951 - Mlig455_052211 {REF} {Length: 3367} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=210.9]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=144.4]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=125, Expect=9e-30]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=125, Expect=6e-30]; ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=120, Expect=4e-28]} {Dmel: FBgn0015519, nAChRalpha3, nicotinic Acetylcholine Receptor alpha3, [Score=111, Expect=9e-25]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=135, Expect=2e-33]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=123, Expect=3e-29]} {RNA1509_30974} {RNA1310_28768.1} {RNA815_26436}
3. MligTC455_45174 1447 30.15 Mlig455_058539

Neo: -

Age: -

Region-enriched R2: 2.293/0.00024

MLX 1.681 - - 0.725 - 0.956 - Mlig455_058539 {REF} {Length: 4178} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=41.6]} {Human: ENSG00000108788, MLX, MLX, MAX dimerization protein, [RH, Score=145, Expect=5e-42]} {Mouse: ENSMUSG00000017801, Mlx, MAX-like protein X, [RH, Score=144, Expect=8e-42]} {Dmel: FBgn0039509, bigmax, [RH, Score=130, Expect=2e-36]} {Smed: dd_Smed_v6_3140_0_1, dd_Smed_v6_3140_0_1, [RH, Score=163, Expect=3e-48]} {RNA1509_10793} {RNA1310_22883.1, RNA1509_10793} {RNA1509_10793, RNA815_10829}
4. MligTC455_45173 1421 29.61 Mlig455_000256

Neo: -

Age: Up-Down-Up

Region-enriched R2: 2.313/0.00035

1.677 - - 0.720 - 0.957 - Mlig455_000256 {REF} {Length: 574} {RNA1509_48066} {RNA1310_71808.1} {RNA815_32033}
5. MligTC455_24028 4831 100.64 Mlig455_045099

Neo: -

Age: Down-Up-Up

Region-enriched R7: 4.473/0.00000
Region-enriched R8: 3.347/0.00002

Regeneration-downregulated BL: -5.638

Regeneration-depleted BL: -5.638

0.97 - - - - 0.970 - Mlig455_045099 {REF} {Length: 970} {Pfam: FMRFamide related peptide family [PF01581.18, score=27.3]} {Celegans: WBGene00001449, flp-6, FMRFamide-like neuropeptides 6 QQDSEVEREMM KSAYMRF-amide 1 KSAYMRF-amide 2 KSAYMRF-amide 3 KSAYMRF-amide 4 KSAYMRF-amide 5 KSAYMRF-amide 6, [Score=45.8, Expect=5e-06]} {Smed: dd_Smed_v6_1724_0_1, dd_Smed_v6_1724_0_1, [Score=43.5, Expect=5e-06]} {RNA1509_13084} {RNA1310_66177} {RNA815_9232.1}
6. MligTC455_48609 3538 73.7 Mlig455_037431, Mlig455_037454, Mlig455_037501

Neo: -

Age: -

Region-specific R2: 3.134

Region-enriched R2: 1.985/0.00000

Regeneration-downregulated BL: -2.003

Regeneration-depleted BL: -2.003

CAPN5 0.968 - - - - 0.968 -

Mlig455_037431 {REF} {Length: 2455} {Pfam: Calpain family cysteine protease [PF00648.23, score=124.0]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=106, Expect=2e-23]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=103, Expect=1e-22]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=2e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=103, Expect=5e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}

Mlig455_037454 {REF} {Length: 1043} {RNA1509_15549} {RNA1310_57168} {RNA815_30048}

Mlig455_037501 {REF} {Length: 2687} {Pfam: Calpain family cysteine protease [PF00648.23, score=123.7]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=108, Expect=6e-24]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=105, Expect=5e-23]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=3e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=104, Expect=4e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}
7. MligTC455_44513 1822 37.96 Mlig455_044390

Neo: -

Age: Down-Up-Up

Region-specific R2: 2.967

Region-enriched R2: 2.054/0.00008

0.959 - - - - 0.959 - Mlig455_044390 {REF} {Length: 727} {Smed: dd_Smed_v6_5576_0_1, dd_Smed_v6_5576_0_1, [Score=93.2, Expect=5e-25]} {RNA1509_30750, RNA1509_53240, RNA1509_6792} {RNA1310_36193, RNA1509_30750, RNA1509_53240, RNA1509_6792} {RNA1509_30750, RNA1509_53240, RNA1509_6792, RNA815_16957}
8. MligTC455_51184 3569 74.36 Mlig455_015275

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.511

Region-enriched R7: 2.009/0.00500

RRBP1 0.959 - - - - 0.959 - Mlig455_015275 {REF} {Length: 1199} {Human: ENSG00000125844, RRBP1, ribosome binding protein 1, [Score=76.6, Expect=2e-15]} {Mouse: ENSMUSG00000027422, Rrbp1, ribosome binding protein 1, [Score=83.2, Expect=7e-18]} {Celegans: WBGene00001446, flp-3, FMRFamide-like neuropeptides 3 SPLGTMRF-amide TPLGTMRF-amide SAEPFGTMRF-amide NPENDTPFGTMRF-amide ASEDALFGTMRF-amide EAEEPLGTMRF-amide SADDSAPFGTMRF-amide NPLGTMRF-amide, [Score=44.7, Expect=1e-05]} {RNA1509_7521} {RNA1310_33007.1} {RNA815_34283}
9. MligTC455_51183 3580 74.57 Mlig455_015151

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.516

Region-enriched R7: 1.993/0.00499

RRBP1 0.957 - - - - 0.957 - Mlig455_015151 {REF} {Length: 1212} {Human: ENSG00000125844, RRBP1, ribosome binding protein 1, [Score=79.0, Expect=5e-16]} {Mouse: ENSMUSG00000027422, Rrbp1, ribosome binding protein 1, [Score=84.0, Expect=4e-18]} {Celegans: WBGene00001446, flp-3, FMRFamide-like neuropeptides 3 SPLGTMRF-amide TPLGTMRF-amide SAEPFGTMRF-amide NPENDTPFGTMRF-amide ASEDALFGTMRF-amide EAEEPLGTMRF-amide SADDSAPFGTMRF-amide NPLGTMRF-amide, [Score=45.1, Expect=9e-06]} {RNA1509_7521} {RNA1310_33007.1} {RNA815_34284}
10. MligTC455_25113 762 15.87 Mlig455_020768

Neo: -

Age: Down-Up-Down

Region-enriched R7: 2.653/0.00004
Region-enriched R2: 2.201/0.02449

0.956 - - - - 0.956 - Mlig455_020768 {REF} {Length: 810} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [Score=46.2, Expect=1e-06]} {RNA1509_36958} {RNA1310_50245} {RNA815_48543}
11. MligTC455_51764 938 19.55 Mlig455_016061

Neo: -

Age: -

Region-specific R2: 2.881

Region-enriched R2: 1.672/0.00180

0.953 - - - - 0.953 - Mlig455_016061 {REF} {Length: 649} {RNA1509_58232} {RNA1310_60107.1, RNA1509_58232} {RNA1509_58232, RNA815_31573}
12. MligTC455_21389 173 3.6 Mlig455_012718

Neo: -

Age: -

SLC9B2 0.95 - - - - 0.950 - Mlig455_012718 {REF} {Length: 3209} {Pfam: Sodium/hydrogen exchanger family [PF00999.23, score=114.5]; Sodium/glutamate symporter [PF03616.16, score=18.4]} {Human: ENSG00000164038, SLC9B2, solute carrier family 9 member B2, [Score=320, Expect=3e-100]} {Mouse: ENSMUSG00000050150, Slc9b1, solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1, [RH, Score=303, Expect=5e-94]} {Dmel: FBgn0031865, Nha1, Na[+]/H[+] hydrogen antiporter 1, [Score=257, Expect=4e-75]} {Celegans: WBGene00009618, F41E7.2, [Score=136, Expect=9e-34]} {Smed: dd_Smed_v6_7736_0_2, dd_Smed_v6_7736_0_2, [RH, Score=359, Expect=2e-116]} {RNA1509_19376} {RNA1310_19487} {RNA815_52764}
13. MligTC455_45156 591 12.3 Mlig455_018705, Mlig455_018722, Mlig455_018742, Mlig455_018910

Neo: -

Age: Up-Down-Up

0.95 - - 0.950 - - -

Mlig455_018705 {REF} {Length: 1236} {TRANSSPLICED} {Pfam: Tctex-1 family [PF03645.15, score=32.6]} {RNA1310_45943} {RNA815_58689}

Mlig455_018722 {REF} {Length: 1053} {Pfam: Tctex-1 family [PF03645.15, score=32.6]} {RNA1310_45943} {RNA815_58689}

Mlig455_018742 {REF} {Length: 1155} {TRANSSPLICED} {Pfam: Tctex-1 family [PF03645.15, score=30.7]} {Mouse: ENSMUSG00000047671, Tctex1d4, Tctex1 domain containing 4, [Score=47.0, Expect=5e-06]} {RNA1310_45943} {RNA815_58689}

Mlig455_018910 {REF} {Length: 1189} {Pfam: Tctex-1 family [PF03645.15, score=32.6]} {RNA1310_45943} {RNA815_58689}
14. MligTC455_51763 1421 29.6 Mlig455_015843

Neo: -

Age: -

Region-specific R2: 3.066

Region-enriched R2: 2.560/0.00003

0.95 - - - - 0.950 - Mlig455_015843 {REF} {Length: 805} {RNA1509_26419, RNA1509_39553, RNA1509_39658} {RNA1310_60107.2, RNA1509_26419, RNA1509_39553, RNA1509_39658} {RNA1509_26419, RNA1509_39553, RNA1509_39658, RNA815_31573}

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