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Results for MligTC455_25106

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_25106 38 0.79 Mlig455_001755, Mlig455_001778

Neo: -

Age: -

Region-enriched R2: 9.161/0.00275

AGTR2, NPFFR2

Mlig455_001755 {REF} {Length: 2284} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=30.7]} {Human: ENSG00000180772, AGTR2, angiotensin II receptor type 2, [Score=57.4, Expect=2e-09]} {Mouse: ENSMUSG00000031210, Gpr165, G protein-coupled receptor 165, [Score=58.9, Expect=5e-10]; ENSMUSG00000068122, Agtr2, angiotensin II receptor, type 2, [Score=58.2, Expect=8e-10]} {Dmel: FBgn0038880, SIFaR, SIFamide receptor, [Score=60.8, Expect=1e-10]} {Celegans: WBGene00006576, tkr-1, Probable G-protein coupled receptor tkr-1, [Score=48.9, Expect=6e-07]} {Smed: dd_Smed_v6_29182_0_1, dd_Smed_v6_29182_0_1, [Score=86.7, Expect=3e-20]} {RNA1310_104492} {RNA815_26451}

Mlig455_001778 {REF} {Length: 2260} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=174.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=50.4]} {Human: ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=139, Expect=1e-35]; ENSG00000137252, HCRTR2, hypocretin receptor 2, [Score=139, Expect=5e-36]} {Mouse: ENSMUSG00000028778, Hcrtr1, hypocretin (orexin) receptor 1, [Score=145, Expect=5e-39]; ENSMUSG00000035528, Npffr2, neuropeptide FF receptor 2, [Score=142, Expect=6e-38]; ENSMUSG00000032360, Hcrtr2, hypocretin (orexin) receptor 2, [Score=139, Expect=3e-36]} {Dmel: FBgn0038880, SIFaR, SIFamide receptor, [Score=181, Expect=6e-50]} {Celegans: WBGene00016842, npr-35, NeuroPeptide Receptor family, [RH, Score=127, Expect=6e-33]} {Smed: dd_Smed_v6_29182_0_1, dd_Smed_v6_29182_0_1, [RH, Score=235, Expect=8e-74]} {RNA1310_139909} {RNA815_26451}

Cumulative graph for MligTC455_25106

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -11.366 1.185 0.99976 1.00000
RegionR2 9.161 1.185 0.00006 0.00275
RegionR3 2.985 1.185 0.99976 1.00000
RegionR4 -1.576 1.185 0.99968 1.00000
RegionR5 3.827 1.185 0.03762 0.15241
RegionR6 2.362 1.185 0.99973 1.00000
RegionR7 0.158 1.185 0.99973 1.00000
RegionR8 -5.551 1.185 0.99950 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 3.19 1.185 0.99988 1.00000
RegenerationR2 0.202 1.185 0.82975 0.99781
RegenerationR3 3.765 1.185 0.01622 0.23323
RegenerationR4 5.058 1.185 0.00059 0.02435
RegenerationR5 1.539 1.185 0.15999 0.58352
RegenerationR6 2.757 1.185 0.12741 0.43881
RegenerationBL 1.752 1.185 0.99991 1.00000
RegenerationTP 2.093 1.185 0.99990 1.00000


Genes with expression patterns similar to MligTC455_25106

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_25106 38 0.79 Mlig455_001755, Mlig455_001778

Neo: -

Age: -

Region-enriched R2: 9.161/0.00275

AGTR2, NPFFR2 4 - - 1.000 1.000 1.000 1.000

Mlig455_001755 {REF} {Length: 2284} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=30.7]} {Human: ENSG00000180772, AGTR2, angiotensin II receptor type 2, [Score=57.4, Expect=2e-09]} {Mouse: ENSMUSG00000031210, Gpr165, G protein-coupled receptor 165, [Score=58.9, Expect=5e-10]; ENSMUSG00000068122, Agtr2, angiotensin II receptor, type 2, [Score=58.2, Expect=8e-10]} {Dmel: FBgn0038880, SIFaR, SIFamide receptor, [Score=60.8, Expect=1e-10]} {Celegans: WBGene00006576, tkr-1, Probable G-protein coupled receptor tkr-1, [Score=48.9, Expect=6e-07]} {Smed: dd_Smed_v6_29182_0_1, dd_Smed_v6_29182_0_1, [Score=86.7, Expect=3e-20]} {RNA1310_104492} {RNA815_26451}

Mlig455_001778 {REF} {Length: 2260} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=174.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=50.4]} {Human: ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=139, Expect=1e-35]; ENSG00000137252, HCRTR2, hypocretin receptor 2, [Score=139, Expect=5e-36]} {Mouse: ENSMUSG00000028778, Hcrtr1, hypocretin (orexin) receptor 1, [Score=145, Expect=5e-39]; ENSMUSG00000035528, Npffr2, neuropeptide FF receptor 2, [Score=142, Expect=6e-38]; ENSMUSG00000032360, Hcrtr2, hypocretin (orexin) receptor 2, [Score=139, Expect=3e-36]} {Dmel: FBgn0038880, SIFaR, SIFamide receptor, [Score=181, Expect=6e-50]} {Celegans: WBGene00016842, npr-35, NeuroPeptide Receptor family, [RH, Score=127, Expect=6e-33]} {Smed: dd_Smed_v6_29182_0_1, dd_Smed_v6_29182_0_1, [RH, Score=235, Expect=8e-74]} {RNA1310_139909} {RNA815_26451}
2. MligTC455_26091 161 3.36 Mlig455_047190

Neo: -

Age: -

Region-enriched R2: 4.521/0.00020

3.657 - - 0.928 0.823 0.937 0.969 Mlig455_047190 {REF} {Length: 2450} {Pfam: Lectin C-type domain [PF00059.23, score=23.6]} {RNA1509_2912} {RNA1310_27113} {RNA815_24719}
3. MligTC455_44120 125 2.61 Mlig455_041513

Neo: -

Age: Up-Down-Down

Region-enriched R2: 7.169/0.00020

3.547 - - 0.968 0.761 0.936 0.882 Mlig455_041513 {REF} {Length: 644} {NoTransDecoderORF} {RNA1310_39164} {RNA815_4344}
4. MligTC455_49557 280 5.82 Mlig455_017273

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.728

Region-specific R2: 3.642

Region-enriched R2: 3.187/0.00196

3.512 - - 0.918 0.801 0.964 0.829 Mlig455_017273 {REF} {Length: 1333} {RNA1509_52848} {RNA1310_64923, RNA1509_52848} {RNA1509_52848, RNA815_51063}
5. MligTC455_26092 67 1.39 Mlig455_048489

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.677

Region-enriched R2: 4.303/0.01110

3.396 - - 0.879 0.715 0.851 0.951 Mlig455_048489 {REF} {Length: 2319} {Pfam: Lectin C-type domain [PF00059.23, score=23.3]} {RNA1509_25383} {RNA1310_27113} {RNA815_24719}
6. MligTC455_45622 647 13.48 Mlig455_069391

Neo: -

Age: -

Region-specific R2: 5.132

Region-enriched R2: 3.915/0.00000

Regeneration-downregulated R2: -2.412

Regeneration-depleted R2: -2.412

3.358 - - 0.805 0.724 0.950 0.879 Mlig455_069391 {REF} {Length: 971} {Smed: dd_Smed_v6_2575_0_1, dd_Smed_v6_2575_0_1, [Score=45.1, Expect=4e-07]} {RNA1509_31982} {RNA1310_46295} {RNA815_23543}
7. MligTC455_41106 42 0.88 Mlig455_010275

Neo: -

Age: -

Region-enriched R2: 5.386/0.03242

CALM1 3.221 - - 0.746 0.794 0.956 0.725 Mlig455_010275 {REF} {Length: 1557} {Pfam: EF hand [PF00036.34, score=32.5]; EF-hand domain pair [PF13499.8, score=30.4]; EF-hand domain [PF13405.8, score=29.3]} {Human: ENSG00000198668, CALM1, calmodulin 1, [Score=67.0, Expect=4e-14]; ENSG00000160014, CALM3, calmodulin 3, [Score=67.0, Expect=4e-14]; ENSG00000143933, CALM2, calmodulin 2, [Score=67.0, Expect=4e-14]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=67.0, Expect=3e-14]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=67.0, Expect=3e-14]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=67.0, Expect=3e-14]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=63.9, Expect=5e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=66.2, Expect=4e-14]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=66.6, Expect=3e-14]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=66.6, Expect=2e-14]} {RNA1310_51265}
8. MligTC455_19875 82 1.71 Mlig455_024408

Neo: -

Age: Down-Up-Down

2.838 - - 0.938 - 0.957 0.943 Mlig455_024408 {REF} {Length: 2479} {Pfam: CD20-like family [PF04103.17, score=40.9]} {Mouse: ENSMUSG00000048004, Tmem196, transmembrane protein 196, [Score=63.5, Expect=2e-12]} {Smed: dd_Smed_v6_14043_0_1, dd_Smed_v6_14043_0_1, [Score=184, Expect=5e-59]} {RNA1509_25506} {RNA1310_4968.1} {RNA815_23744}
9. MligTC455_14898 41 0.86 Mlig455_011988

Neo: -

Age: -

2.807 - - 0.955 - 0.945 0.907 Mlig455_011988 {REF} {Length: 858} {Pfam: Lectin C-type domain [PF00059.23, score=28.2]} {RNA1509_20946} {RNA1310_48952} {RNA815_4785.1}
10. MligTC455_40905 53 1.1 Mlig455_002794, Mlig455_002809

Neo: -

Age: -

CHL1 2.803 - - 0.963 - 0.971 0.869

Mlig455_002794 {REF} {Length: 4845} {Pfam: Immunoglobulin domain [PF13927.8, score=205.6]; Immunoglobulin I-set domain [PF07679.18, score=151.2]; Immunoglobulin domain [PF00047.27, score=122.8]; Immunoglobulin domain [PF13895.8, score=109.6]; Fibronectin type III domain [PF00041.23, score=98.8]; Immunoglobulin V-set domain [PF07686.19, score=65.4]; Immunoglobulin domain [PF18452.3, score=21.7]} {Human: ENSG00000134121, CHL1, cell adhesion molecule L1 like, [RH, Score=340, Expect=1e-96]} {Mouse: ENSMUSG00000031391, L1cam, L1 cell adhesion molecule, [RH, Score=339, Expect=2e-96]; ENSMUSG00000030077, Chl1, cell adhesion molecule L1-like, [RH, Score=335, Expect=4e-95]} {Dmel: FBgn0264975, Nrg, Neuroglian, [Score=358, Expect=2e-103]} {Celegans: WBGene00002243, lad-2, Immunoglobulin domain-containing protein Y54G2A.25; L1 CAM ADhesion molecule homolog; LAD-2 long isoform, [Score=287, Expect=1e-79]} {Smed: dd_Smed_v6_1916_0_1, dd_Smed_v6_1916_0_1, [Score=486, Expect=3e-148]} {RNA1310_42673}

Mlig455_002809 {REF} {Length: 4785} {Pfam: Immunoglobulin domain [PF13927.8, score=155.8]; Immunoglobulin I-set domain [PF07679.18, score=111.7]; Fibronectin type III domain [PF00041.23, score=99.0]; Immunoglobulin domain [PF00047.27, score=90.9]; Immunoglobulin domain [PF13895.8, score=77.2]; Immunoglobulin V-set domain [PF07686.19, score=38.0]} {Human: ENSG00000134121, CHL1, cell adhesion molecule L1 like, [Score=292, Expect=8e-81]; ENSG00000163531, NFASC, neurofascin, [Score=290, Expect=4e-80]} {Mouse: ENSMUSG00000031391, L1cam, L1 cell adhesion molecule, [Score=294, Expect=2e-81]; ENSMUSG00000026442, Nfasc, neurofascin, [Score=290, Expect=2e-80]; ENSMUSG00000030077, Chl1, cell adhesion molecule L1-like, [Score=285, Expect=2e-78]; ENSMUSG00000020598, Nrcam, neuronal cell adhesion molecule, [Score=282, Expect=7e-78]} {Dmel: FBgn0264975, Nrg, Neuroglian, [Score=315, Expect=1e-88]} {Celegans: WBGene00002243, lad-2, Immunoglobulin domain-containing protein Y54G2A.25; L1 CAM ADhesion molecule homolog; LAD-2 long isoform, [Score=251, Expect=9e-68]} {Smed: dd_Smed_v6_1916_0_1, dd_Smed_v6_1916_0_1, [Score=441, Expect=4e-132]} {RNA1310_42673}
11. MligTC455_15184 33 0.69 Mlig455_065087

Neo: -

Age: -

2.794 - - 0.896 - 0.961 0.937 Mlig455_065087 {REF} {Length: 2555} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=183.3]} {Mouse: ENSMUSG00000030340, Scnn1a, sodium channel, nonvoltage-gated 1 alpha, [Score=48.5, Expect=1e-05]} {Celegans: WBGene00009073, delm-1, DEgenerin Linked to Mechanosensation, [Score=68.2, Expect=1e-11]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [RH, Score=125, Expect=3e-30]} {RNA1310_11413} {RNA815_11497}
12. MligTC455_36194 30 0.61 Mlig455_064360, Mlig455_064382

Neo: -

Age: -

B3GNT4 2.793 - - 0.957 - 0.932 0.904

Mlig455_064360 {REF} {Length: 3119} {Pfam: Galactosyltransferase [PF01762.23, score=116.7]} {Human: ENSG00000176383, B3GNT4, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, [Score=101, Expect=5e-23]} {Mouse: ENSMUSG00000031803, B3gnt3, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, [Score=94.7, Expect=9e-21]; ENSMUSG00000051650, B3gnt2, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, [Score=94.0, Expect=2e-20]; ENSMUSG00000067370, B3galt4, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4, [Score=93.6, Expect=3e-20]; ENSMUSG00000029431, B3gnt4, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, [Score=93.2, Expect=2e-20]; ENSMUSG00000022686, B3gnt5, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5, [Score=91.7, Expect=1e-19]} {Dmel: FBgn0031988, CG8668, [Score=90.1, Expect=8e-19]} {Celegans: WBGene00007104, B0024.15, Hexosyltransferase, [RH, Score=90.9, Expect=8e-20]} {Smed: dd_Smed_v6_9789_0_1, dd_Smed_v6_9789_0_1, [Score=165, Expect=5e-47]} {RNA1310_43172} {RNA815_26726}

Mlig455_064382 {REF} {Length: 3084} {Pfam: Galactosyltransferase [PF01762.23, score=116.7]} {Human: ENSG00000176383, B3GNT4, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, [Score=101, Expect=5e-23]} {Mouse: ENSMUSG00000031803, B3gnt3, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, [Score=94.7, Expect=9e-21]; ENSMUSG00000051650, B3gnt2, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, [Score=94.4, Expect=2e-20]; ENSMUSG00000029431, B3gnt4, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, [Score=93.6, Expect=2e-20]; ENSMUSG00000067370, B3galt4, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4, [Score=93.6, Expect=2e-20]; ENSMUSG00000022686, B3gnt5, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5, [Score=92.0, Expect=9e-20]} {Dmel: FBgn0031988, CG8668, [Score=90.1, Expect=8e-19]} {Celegans: WBGene00007104, B0024.15, Hexosyltransferase, [RH, Score=90.9, Expect=8e-20]} {Smed: dd_Smed_v6_9789_0_1, dd_Smed_v6_9789_0_1, [Score=165, Expect=5e-47]} {RNA1310_43172} {RNA815_26726}
13. MligTC455_19876 135 2.82 Mlig455_024520, Mlig455_024523

Neo: -

Age: -

2.79 - - 0.930 - 0.961 0.899

Mlig455_024520 {REF} {Length: 2352} {Pfam: CD20-like family [PF04103.17, score=40.9]} {Mouse: ENSMUSG00000048004, Tmem196, transmembrane protein 196, [Score=63.5, Expect=2e-12]} {Smed: dd_Smed_v6_14043_0_1, dd_Smed_v6_14043_0_1, [Score=184, Expect=5e-59]} {RNA1509_25506} {RNA1310_9338} {RNA815_23744}

Mlig455_024523 {REF} {Length: 2311} {Smed: dd_Smed_v6_14043_0_1, dd_Smed_v6_14043_0_1, [Score=153, Expect=3e-47]} {RNA1509_25506} {RNA1310_9338} {RNA815_23744}
14. MligTC455_19249 90 1.86 Mlig455_054092

Neo: -

Age: Down-Up-Up

Region-enriched R2: 7.298/0.00139

2.775 - - 0.947 - 0.973 0.855 Mlig455_054092 {REF} {Length: 667} {TRANSSPLICED} {RNA1509_57448} {RNA1310_51394, RNA1509_57448} {RNA1509_57448, RNA815_26076}
15. MligTC455_30463 95 1.98 Mlig455_000250, Mlig455_058521, Mlig455_058532

Neo: -

Age: -

2.772 - - 0.846 - 0.961 0.965

Mlig455_000250 {REF} {Length: 1994} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=19.7]} {RNA1310_59451} {RNA815_40085}

Mlig455_058521 {REF} {Length: 1237} {RNA1310_56656} {RNA815_40085}

Mlig455_058532 {REF} {Length: 1973} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=19.5]} {RNA1310_59451} {RNA815_40085}
16. MligTC455_50778 36 0.76 Mlig455_042296

Neo: -

Age: -

GPR50 2.771 - - 0.955 - 0.912 0.904 Mlig455_042296 {REF} {Length: 1415} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=116.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=40.0]; Olfactory receptor [PF13853.8, score=34.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=33.9]} {Human: ENSG00000102195, GPR50, G protein-coupled receptor 50, [Score=124, Expect=4e-31]; ENSG00000134640, MTNR1B, melatonin receptor 1B, [Score=119, Expect=2e-30]} {Mouse: ENSMUSG00000054764, Mtnr1a, melatonin receptor 1A, [Score=120, Expect=4e-31]; ENSMUSG00000056380, Gpr50, G-protein-coupled receptor 50, [Score=119, Expect=2e-29]; ENSMUSG00000050901, Mtnr1b, melatonin receptor 1B, [Score=118, Expect=5e-30]} {Dmel: FBgn0038980, Octbeta1R, Octopamine beta1 receptor, [Score=92.0, Expect=1e-20]} {Celegans: WBGene00006428, tkr-3, TachyKinin Receptor family, [Score=69.7, Expect=4e-13]} {Smed: dd_Smed_v6_65999_0_1, dd_Smed_v6_65999_0_1, [Score=84.7, Expect=1e-18]} {RNA1310_66047} {RNA815_34066}
17. MligTC455_46452 134 2.79 Mlig455_048151

Neo: -

Age: -

Region-specific R2: 6.389

Region-enriched R2: 7.075/0.00014

Regeneration-downregulated R2: -3.162

Regeneration-depleted R2: -3.162

2.766 - - 0.896 - 0.973 0.897 Mlig455_048151 {REF} {Length: 618} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=25.7]} {RNA1310_62963} {RNA815_31352}
18. MligTC455_00245 15 0.32 Mlig455_040042

Neo: -

Age: -

GPR17 2.763 - - 0.954 - 0.916 0.893 Mlig455_040042 {REF} {Length: 1332} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=36.0]} {Human: ENSG00000144230, GPR17, G protein-coupled receptor 17, [Score=48.9, Expect=6e-06]} {Smed: dd_Smed_v6_61185_0_1, dd_Smed_v6_61185_0_1, [Score=70.9, Expect=1e-14]} {RNA1310_142905}
19. MligTC455_40687 28 0.58 Mlig455_040563, Mlig455_062078

Neo: -

Age: -

PDE1C 2.763 - - 0.857 - 0.969 0.937

Mlig455_040563 {REF} {Length: 1798} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=268.1]; 3'5'-cyclic nucleotide phosphodiesterase N-terminal [PF08499.14, score=29.0]} {Human: ENSG00000154678, PDE1C, phosphodiesterase 1C, [Score=362, Expect=2e-117]; ENSG00000115252, PDE1A, phosphodiesterase 1A, [Score=358, Expect=2e-117]} {Mouse: ENSMUSG00000004347, Pde1c, phosphodiesterase 1C, [Score=362, Expect=5e-118]; ENSMUSG00000059173, Pde1a, phosphodiesterase 1A, calmodulin-dependent, [Score=362, Expect=7e-120]} {Dmel: FBgn0264815, Pde1c, Phosphodiesterase 1c, [Score=346, Expect=4e-108]} {Celegans: WBGene00011433, pde-1, Probable 3',5'-cyclic phosphodiesterase pde-1, [Score=347, Expect=3e-113]} {Smed: dd_Smed_v6_21546_0_1, dd_Smed_v6_21546_0_1, [Score=396, Expect=7e-133]} {RNA1310_80402}

Mlig455_062078 {REF} {Length: 1807} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=268.6]; 3'5'-cyclic nucleotide phosphodiesterase N-terminal [PF08499.14, score=29.1]} {Human: ENSG00000154678, PDE1C, phosphodiesterase 1C, [Score=356, Expect=3e-115]; ENSG00000115252, PDE1A, phosphodiesterase 1A, [Score=355, Expect=5e-116]} {Mouse: ENSMUSG00000059173, Pde1a, phosphodiesterase 1A, calmodulin-dependent, [Score=359, Expect=1e-118]; ENSMUSG00000004347, Pde1c, phosphodiesterase 1C, [Score=356, Expect=8e-116]} {Dmel: FBgn0264815, Pde1c, Phosphodiesterase 1c, [Score=347, Expect=2e-108]} {Celegans: WBGene00011433, pde-1, Probable 3',5'-cyclic phosphodiesterase pde-1, [Score=347, Expect=3e-113]} {Smed: dd_Smed_v6_26758_0_1, dd_Smed_v6_26758_0_1, [Score=394, Expect=3e-132]} {RNA1509_46211} {RNA1310_80402} {RNA815_55704}
20. MligTC455_38667 17 0.35 Mlig455_059621

Neo: -

Age: -

2.757 - - 0.960 - 0.890 0.907 Mlig455_059621 {REF} {Length: 1297} {RNA1310_51041}
21. MligTC455_30634 114 2.38 Mlig455_025888

Neo: -

Age: Up-Down-Up

Region-enriched R2: 6.750/0.00140

2.75 - - 0.939 - 0.980 0.831 Mlig455_025888 {REF} {Length: 5266} {Pfam: Integrase core domain [PF00665.28, score=50.8]; DDE superfamily endonuclease [PF13358.8, score=22.0]} {Smed: dd_Smed_v6_1574_6_72, dd_Smed_v6_1574_6_72, [Score=149, Expect=3e-41]} {RNA1509_47056} {RNA1310_5710.1} {RNA815_6291.1}
22. MligTC455_13866 60 1.26 Mlig455_059198

Neo: -

Age: -

2.725 - - 0.957 - 0.920 0.848 Mlig455_059198 {REF} {Length: 561} {NoTransDecoderORF} {RNA1310_89423} {RNA815_50610}
23. MligTC455_41724 23 0.49 Mlig455_001647

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.847

2.72 - - 0.864 - 0.958 0.898 Mlig455_001647 {REF} {Length: 1808} {RNA1310_22665} {RNA815_13308}
24. MligTC455_16606 108 2.26 Mlig455_034973, Mlig455_053711, Mlig455_060000

Neo: -

Age: -

Region-enriched R2: 5.697/0.00617

GLRA2 2.707 - - 0.950 - 0.910 0.847

Mlig455_034973 {REF} {Length: 1000} {RNA1310_100434}

Mlig455_053711 {REF} {Length: 2327} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=52.0]} {Human: ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=60.8, Expect=3e-09]; ENSG00000109738, GLRB, glycine receptor beta, [Score=60.1, Expect=5e-09]} {Mouse: ENSMUSG00000023267, Gabrr2, gamma-aminobutyric acid (GABA) C receptor, subunit rho 2, [Score=61.6, Expect=1e-09]; ENSMUSG00000028020, Glrb, glycine receptor, beta subunit, [Score=61.2, Expect=2e-09]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=60.5, Expect=2e-09]} {Dmel: FBgn0010240, Lcch3, Ligand-gated chloride channel homolog 3, [Score=58.9, Expect=6e-09]} {Celegans: WBGene00001587, ggr-2, GABA/Glycine Receptor family (See gbr), [Score=60.8, Expect=1e-09]} {RNA1310_56609} {RNA815_37711}

Mlig455_060000 {REF} {Length: 2781} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=52.0]} {Human: ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=62.0, Expect=1e-09]; ENSG00000109738, GLRB, glycine receptor beta, [Score=60.1, Expect=5e-09]} {Mouse: ENSMUSG00000023267, Gabrr2, gamma-aminobutyric acid (GABA) C receptor, subunit rho 2, [Score=62.0, Expect=7e-10]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=62.0, Expect=7e-10]; ENSMUSG00000028020, Glrb, glycine receptor, beta subunit, [Score=61.2, Expect=2e-09]} {Dmel: FBgn0010240, Lcch3, Ligand-gated chloride channel homolog 3, [Score=58.9, Expect=5e-09]} {Celegans: WBGene00001587, ggr-2, GABA/Glycine Receptor family (See gbr), [Score=60.8, Expect=1e-09]} {RNA1509_50322} {RNA1310_56609} {RNA815_37711}
25. MligTC455_49863 62 1.29 Mlig455_019320, Mlig455_019542

Neo: -

Age: -

SHOX2 2.699 - - 0.951 - 0.963 0.785

Mlig455_019320 {REF} {Length: 1251} {Pfam: Homeodomain [PF00046.31, score=83.4]; Homeobox KN domain [PF05920.13, score=23.0]} {Human: ENSG00000168779, SHOX2, short stature homeobox 2, [Score=88.2, Expect=5e-21]; ENSG00000185960, SHOX, short stature homeobox, [Score=86.3, Expect=7e-20]} {Mouse: ENSMUSG00000027833, Shox2, short stature homeobox 2, [Score=88.2, Expect=3e-21]} {Dmel: FBgn0085396, CG34367, [Score=89.4, Expect=7e-21]} {Celegans: WBGene00006744, unc-4, Homeobox protein unc-4, [Score=84.0, Expect=2e-19]} {Smed: dd_Smed_v6_22163_0_1, dd_Smed_v6_22163_0_1, [Score=87.0, Expect=8e-20]} {RNA1310_51707} {RNA815_41055}

Mlig455_019542 {REF} {Length: 1249} {Pfam: Homeodomain [PF00046.31, score=83.4]; Homeobox KN domain [PF05920.13, score=23.0]} {Human: ENSG00000168779, SHOX2, short stature homeobox 2, [Score=88.6, Expect=4e-21]; ENSG00000185960, SHOX, short stature homeobox, [Score=86.3, Expect=6e-20]} {Mouse: ENSMUSG00000027833, Shox2, short stature homeobox 2, [Score=88.6, Expect=3e-21]} {Dmel: FBgn0085396, CG34367, [Score=89.4, Expect=7e-21]} {Celegans: WBGene00006744, unc-4, Homeobox protein unc-4, [Score=86.7, Expect=3e-20]} {Smed: dd_Smed_v6_22163_0_1, dd_Smed_v6_22163_0_1, [Score=87.0, Expect=8e-20]} {RNA1310_51707} {RNA815_41055}
26. MligTC455_14216 241 5.03 Mlig455_044260

Neo: -

Age: Up-Down-Up

Region-enriched R2: 6.597/0.00013

DBH 2.696 - - 0.976 - 0.947 0.773 Mlig455_044260 {REF} {Length: 840} {Pfam: Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=26.2]} {Human: ENSG00000123454, DBH, dopamine beta-hydroxylase, [Score=70.9, Expect=4e-15]} {Mouse: ENSMUSG00000000889, Dbh, dopamine beta hydroxylase, [Score=72.0, Expect=1e-15]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=64.7, Expect=3e-13]} {Celegans: WBGene00006541, tbh-1, Tyramine beta-hydroxylase, [Score=52.4, Expect=5e-09]} {Smed: dd_Smed_v6_42610_0_1, dd_Smed_v6_42610_0_1, [Score=65.1, Expect=1e-13]} {RNA1509_17014} {RNA1310_13801} {RNA815_8852}
27. MligTC455_53546 130 2.72 Mlig455_013326, Mlig455_013334

Neo: -

Age: -

Region-enriched R2: 6.753/0.01892

MMP9 2.684 - - 0.840 - 0.956 0.888

Mlig455_013326 {REF} {Length: 1449} {Pfam: Fibronectin type II domain [PF00040.21, score=92.5]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=87.8, Expect=3e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=82.4, Expect=1e-16]; ENSMUSG00000031740, Mmp2, matrix metallopeptidase 2, [RH, Score=78.6, Expect=2e-15]} {Smed: dd_Smed_v6_14558_0_1, dd_Smed_v6_14558_0_1, [RH, Score=138, Expect=3e-38]} {RNA1310_38631} {RNA815_51136}

Mlig455_013334 {REF} {Length: 1398} {Pfam: Fibronectin type II domain [PF00040.21, score=92.1]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=89.4, Expect=1e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=84.0, Expect=4e-17]} {Smed: dd_Smed_v6_12601_0_1, dd_Smed_v6_12601_0_1, [RH, Score=140, Expect=2e-38]} {RNA1310_38631} {RNA815_51136}
28. MligTC455_03382 210 4.37 Mlig455_057035

Neo: -

Age: -

Region-enriched R2: 3.628/0.00113

PDE1C 2.682 - - 0.772 - 0.951 0.959 Mlig455_057035 {REF} {Length: 2458} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=275.1]; 3'5'-cyclic nucleotide phosphodiesterase N-terminal [PF08499.14, score=94.2]} {Human: ENSG00000154678, PDE1C, phosphodiesterase 1C, [RH, Score=546, Expect=0.0]} {Mouse: ENSMUSG00000004347, Pde1c, phosphodiesterase 1C, [RH, Score=546, Expect=0.0]} {Dmel: FBgn0264815, Pde1c, Phosphodiesterase 1c, [RH, Score=538, Expect=0.0]} {Celegans: WBGene00011433, pde-1, Probable 3',5'-cyclic phosphodiesterase pde-1, [RH, Score=482, Expect=2e-164]} {Smed: dd_Smed_v6_11039_0_2, dd_Smed_v6_11039_0_2, [RH, Score=613, Expect=0.0]} {RNA1509_46084} {RNA1310_8143.1} {RNA815_6002}
29. MligTC455_17178 54 1.12 Mlig455_067758

Neo: -

Age: -

Region-enriched R2: 7.471/0.00007

2.673 - - 0.786 - 0.951 0.936 Mlig455_067758 {REF} {Length: 2301} {RNA1509_44702} {RNA1310_14743} {RNA815_20669.1}
30. MligTC455_44904 1501 31.27 Mlig455_021814

Neo: -

Age: Down-Up-Up

Region-specific R2: 3.865

Region-enriched R2: 3.792/0.00000

2.67 - - 0.897 - 0.965 0.808 Mlig455_021814 {REF} {Length: 959} {RNA1509_15805} {RNA1310_67099.1, RNA1509_15805} {RNA1509_15805, RNA815_17533}
31. MligTC455_23825 29 0.6 Mlig455_002166, Mlig455_002310

Neo: -

Age: Down-Up-Down

NOL4 2.658 - - 0.962 - 0.945 0.751

Mlig455_002166 {REF} {Length: 3243} {Human: ENSG00000101746, NOL4, nucleolar protein 4, [RH, Score=135, Expect=9e-35]} {Mouse: ENSMUSG00000041923, Nol4, nucleolar protein 4, [RH, Score=136, Expect=1e-34]} {Dmel: FBgn0283651, CG46301, [RH, Score=140, Expect=4e-35]} {Smed: dd_Smed_v6_10255_0_1, dd_Smed_v6_10255_0_1, [RH, Score=82.4, Expect=6e-17]} {RNA1509_41791} {RNA1310_36173.1} {RNA815_37287}

Mlig455_002310 {REF} {Length: 2667} {Human: ENSG00000101746, NOL4, nucleolar protein 4, [RH, Score=135, Expect=1e-34]} {Mouse: ENSMUSG00000041923, Nol4, nucleolar protein 4, [RH, Score=136, Expect=1e-34]} {Dmel: FBgn0283651, CG46301, [RH, Score=140, Expect=4e-35]} {Smed: dd_Smed_v6_10255_0_1, dd_Smed_v6_10255_0_1, [RH, Score=82.4, Expect=6e-17]} {RNA1509_41791} {RNA1310_36173.1}
32. MligTC455_23957 33 0.68 Mlig455_015196, Mlig455_068736

Neo: -

Age: -

Region-enriched R2: 7.683/0.01527

2.655 - - 0.959 - 0.789 0.907

Mlig455_015196 {REF} {Length: 1138} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.8]} {RNA1509_30941} {RNA1310_34740} {RNA815_15663}

Mlig455_068736 {REF} {Length: 1580} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=64.0]} {RNA1310_32395.1} {RNA815_15663}
33. MligTC455_49919 745 15.52 Mlig455_017182, Mlig455_048150

Neo: -

Age: -

Region-specific R2: 7.180

Region-enriched R2: 7.978/0.00000

Regeneration-downregulated R2: -4.649

Regeneration-depleted R2: -4.649

2.65 - - 0.784 - 0.953 0.913

Mlig455_017182 {REF} {Length: 576} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1310_60849, RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1509_35830, RNA1509_49816, RNA1509_53987, RNA815_31347}

Mlig455_048150 {REF} {Length: 574} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830} {RNA1310_60849} {RNA815_31347}
34. MligTC455_16061 57 1.18 Mlig455_009277, Mlig455_037029

Neo: -

Age: -

2.641 - - 0.814 - 0.978 0.849

Mlig455_009277 {REF} {Length: 2928} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=77.0, Expect=4e-15]} {RNA1310_73097} {RNA815_27121}

Mlig455_037029 {REF} {Length: 3379} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=76.6, Expect=5e-15]} {RNA1310_73097} {RNA815_27121}
35. MligTC455_14043 12 0.26 Mlig455_016776

Neo: -

Age: -

ANKRD63 2.635 - - 0.960 0.710 0.965 - Mlig455_016776 {REF} {Length: 1715} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=122.1]; Ankyrin repeats (many copies) [PF13637.8, score=70.6]; Ankyrin repeats (many copies) [PF13857.8, score=54.8]; Ankyrin repeat [PF00023.32, score=50.2]; Ankyrin repeat [PF13606.8, score=43.7]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [RH, Score=130, Expect=1e-33]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [RH, Score=131, Expect=9e-34]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=66.2, Expect=3e-11]} {Celegans: WBGene00012124, T28D6.4, [Score=62.8, Expect=3e-10]} {Smed: dd_Smed_v6_11187_0_3, dd_Smed_v6_11187_0_3, [Score=56.6, Expect=2e-08]} {RNA815_38023}
36. MligTC455_48127 47 0.97 Mlig455_037173

Neo: -

Age: -

2.627 - - 0.911 0.764 0.952 - Mlig455_037173 {REF} {Length: 1938} {RNA1310_42908} {RNA815_22744}
37. MligTC455_44159 80 1.67 Mlig455_019040, Mlig455_055663

Neo: -

Age: Down-Up-Up

ADRB1, GALR3 2.624 - - 0.957 0.734 0.933 -

Mlig455_019040 {REF} {Length: 1804} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=78.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=31.3]} {Human: ENSG00000043591, ADRB1, adrenoceptor beta 1, [Score=52.8, Expect=5e-07]} {Mouse: ENSMUSG00000034987, Hrh2, histamine receptor H2, [Score=47.8, Expect=1e-05]} {Dmel: FBgn0038874, ETHR, [Score=49.3, Expect=3e-06]} {Celegans: WBGene00017661, frpr-6, FMRFamide Peptide Receptor family, [Score=54.3, Expect=5e-08]} {Smed: dd_Smed_v6_19933_0_1, dd_Smed_v6_19933_0_1, [RH, Score=124, Expect=9e-33]} {RNA1310_47955} {RNA815_45615}

Mlig455_055663 {REF} {Length: 1667} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=47.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=27.2]} {Human: ENSG00000128310, GALR3, galanin receptor 3, [Score=50.1, Expect=2e-06]} {Smed: dd_Smed_v6_14726_0_1, dd_Smed_v6_14726_0_1, [Score=103, Expect=6e-25]} {RNA1310_86586} {RNA815_45615}
38. MligTC455_52507 60 1.26 Mlig455_016440

Neo: -

Age: -

Region-enriched R2: 5.871/0.01204

2.611 - - 0.863 - 0.953 0.795 Mlig455_016440 {REF} {Length: 1576} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1310_98267}
39. MligTC455_29412 46 0.96 Mlig455_000627, Mlig455_008268, Mlig455_040614

Neo: -

Age: Up-Down-Up

2.608 - - 0.736 - 0.968 0.904

Mlig455_000627 {REF} {Length: 1331} {RNA1310_62571} {RNA815_30942}

Mlig455_008268 {REF} {Length: 1779} {RNA1509_47298} {RNA1310_98344} {RNA815_10804.1}

Mlig455_040614 {REF} {Length: 1016}
40. MligTC455_41988 81 1.68 Mlig455_049279, Mlig455_050624

Neo: -

Age: -

2.597 - - 0.820 - 0.976 0.801

Mlig455_049279 {REF} {Length: 6361} {Pfam: Innexin [PF00876.20, score=408.1]} {Dmel: FBgn0085387, shakB, shaking B, [RH, Score=133, Expect=1e-34]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=341, Expect=5e-114]} {Smed: dd_Smed_v6_11077_0_2, dd_Smed_v6_11077_0_2, [RH, Score=483, Expect=3e-168]} {RNA1509_51082} {RNA1310_22380} {RNA815_25566}

Mlig455_050624 {REF} {Length: 2845} {Pfam: Innexin [PF00876.20, score=408.0]} {Dmel: FBgn0085387, shakB, shaking B, [RH, Score=133, Expect=2e-34]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=342, Expect=3e-114]} {Smed: dd_Smed_v6_11077_0_2, dd_Smed_v6_11077_0_2, [RH, Score=484, Expect=1e-168]} {RNA1509_51082} {RNA1310_22380} {RNA815_1848.2}
41. MligTC455_42785 79 1.65 Mlig455_004724

Neo: -

Age: Down-Up-Down

2.588 - - 0.827 - 0.952 0.809 Mlig455_004724 {REF} {Length: 1460} {NoTransDecoderORF} {RNA1509_29447} {RNA1310_33893.1, RNA1509_29447} {RNA1509_29447, RNA815_16689.1}
42. MligTC455_34925 183 3.82 Mlig455_012715

Neo: -

Age: -

CDKL1 2.569 - - - 0.759 0.950 0.860 Mlig455_012715 {REF} {Length: 2370} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=250.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.6]; RIO1 family [PF01163.24, score=23.0]; ABC1 atypical kinase-like domain [PF03109.18, score=20.8]; Haspin like kinase domain [PF12330.10, score=20.4]; Kinase-like [PF14531.8, score=19.4]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=437, Expect=3e-153]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=424, Expect=2e-147]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=437, Expect=2e-153]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=432, Expect=2e-151]} {Dmel: FBgn0031730, CG7236, [RH, Score=384, Expect=3e-131]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=388, Expect=3e-132]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=472, Expect=5e-167]} {RNA1509_44617} {RNA1310_15038, RNA1509_44617} {RNA1509_44617, RNA815_6379}
43. MligTC455_47642 97 2.02 Mlig455_036511

Neo: -

Age: -

2.563 - - 0.955 - 0.824 0.784 Mlig455_036511 {REF} {Length: 2030} {RNA1509_55500} {RNA1310_26431} {RNA815_24412}
44. MligTC455_24244 290 6.04 Mlig455_062623, Mlig455_067528, Mlig455_070336

Neo: -

Age: Down-Up-Down

Region-enriched R2: 6.603/0.00020

2.558 - - 0.888 0.704 0.966 -

Mlig455_062623 {REF} {Length: 1154} {Pfam: Putative Interleukin 2 receptor, gamma chain [PF15874.7, score=68.1]} {Smed: dd_Smed_v6_15167_0_1, dd_Smed_v6_15167_0_1, [RH, Score=71.6, Expect=3e-16]} {RNA1310_40891} {RNA815_16565}

Mlig455_067528 {REF} {Length: 1190} {Pfam: Putative Interleukin 2 receptor, gamma chain [PF15874.7, score=67.0]} {Smed: dd_Smed_v6_15167_0_1, dd_Smed_v6_15167_0_1, [RH, Score=72.4, Expect=1e-16]} {RNA1310_40891} {RNA815_16565}

Mlig455_070336 {REF} {Length: 859} {Pfam: Putative Interleukin 2 receptor, gamma chain [PF15874.7, score=67.7]} {Smed: dd_Smed_v6_15167_0_1, dd_Smed_v6_15167_0_1, [Score=57.4, Expect=1e-10]} {RNA1310_40891} {RNA815_16565}
45. MligTC455_31114 53 1.1 Mlig455_017272

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.386

SLC10A2 2.552 - - 0.950 0.831 0.771 - Mlig455_017272 {REF} {Length: 2348} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=113.6]; SBF-like CPA transporter family (DUF4137) [PF13593.8, score=38.7]} {Human: ENSG00000125255, SLC10A2, solute carrier family 10 member 2, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [RH, Score=155, Expect=7e-43]} {Dmel: FBgn0030638, CG11655, [Score=157, Expect=7e-43]} {Celegans: WBGene00044650, Y71G10AR.4, [Score=180, Expect=9e-51]} {Smed: dd_Smed_v6_14676_0_1, dd_Smed_v6_14676_0_1, [Score=260, Expect=5e-82]} {RNA1509_52848} {RNA1310_31875.1} {RNA815_14501}
46. MligTC455_44766 87 1.81 Mlig455_054070

Neo: -

Age: -

Region-enriched R2: 8.262/0.00000
Region-enriched R3: 4.728/0.03576
Region-enriched R4: 3.007/0.02771

2.549 - - 0.835 0.744 0.970 - Mlig455_054070 {REF} {Length: 1746} {RNA1310_24217} {RNA815_39411}
47. MligTC455_51238 58 1.21 Mlig455_011511

Neo: -

Age: -

KCNMA1 2.549 - - 0.802 0.783 0.964 - Mlig455_011511 {REF} {Length: 2300} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=100.8]; Ion channel [PF07885.18, score=29.2]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=272, Expect=4e-80]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=271, Expect=4e-79]} {Dmel: FBgn0003429, slo, slowpoke, [Score=180, Expect=8e-48]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=269, Expect=9e-79]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=294, Expect=9e-88]} {RNA1310_5274} {RNA815_44227}
48. MligTC455_48128 18 0.37 Mlig455_052326

Neo: -

Age: -

2.536 - - 0.826 0.738 0.972 - Mlig455_052326 {REF} {Length: 3582} {RNA1310_42908} {RNA815_22744}
49. MligTC455_29874 65 1.36 Mlig455_037947, Mlig455_068699

Neo: -

Age: logFC(26M/2M)=-0.467

ANKRD50 2.515 - - 0.726 - 0.960 0.829

Mlig455_037947 {REF} {Length: 4099} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=309.9]; Ankyrin repeat [PF00023.32, score=295.0]; Ankyrin repeat [PF13606.8, score=230.6]; Ankyrin repeats (many copies) [PF13637.8, score=228.6]; Ankyrin repeats (many copies) [PF13857.8, score=200.7]; Glutamine amidotransferase domain [PF13537.8, score=68.9]; PEGA domain [PF08308.13, score=35.0]; Mab-21 protein [PF03281.16, score=29.5]; Nucleoplasmin/nucleophosmin domain [PF03066.17, score=26.4]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=276, Expect=2e-75]; ENSG00000029534, ANK1, ankyrin 1, [Score=270, Expect=5e-73]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=274, Expect=8e-75]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=256, Expect=7e-69]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=258, Expect=1e-69]} {Smed: dd_Smed_v6_2072_0_29, dd_Smed_v6_2072_0_29, [Score=256, Expect=2e-71]} {RNA1509_26004, RNA1509_28959} {RNA1310_3906.1, RNA1509_28959} {RNA1509_28959, RNA815_1664.1}

Mlig455_068699 {REF} {Length: 2234} {Pfam: Mab-21 protein [PF03281.16, score=31.1]} {RNA1509_26004} {RNA1310_3906.1} {RNA815_1664.1}
50. MligTC455_52814 47 0.97 Mlig455_047356, Mlig455_047365

Neo: -

Age: -

CNTN2 2.505 - - 0.757 0.770 0.978 -

Mlig455_047356 {REF} {Length: 2537} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=57.8]; Immunoglobulin domain [PF13927.8, score=52.6]; Immunoglobulin domain [PF13895.8, score=40.4]; Immunoglobulin domain [PF00047.27, score=40.3]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=25.9]} {Human: ENSG00000184144, CNTN2, contactin 2, [Score=58.5, Expect=3e-08]} {Mouse: ENSMUSG00000053024, Cntn2, contactin 2, [Score=56.6, Expect=8e-08]; ENSMUSG00000061751, Kalrn, kalirin, RhoGEF kinase, [Score=55.1, Expect=2e-07]; ENSMUSG00000020674, Pxdn, peroxidasin, [Score=54.7, Expect=3e-07]} {Dmel: FBgn0264975, Nrg, Neuroglian, [Score=58.2, Expect=2e-08]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [RH, Score=99.8, Expect=2e-22]} {RNA1509_60115} {RNA1310_31768} {RNA815_18728}

Mlig455_047365 {REF} {Length: 3489} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=57.9]; Immunoglobulin domain [PF13927.8, score=52.8]; Immunoglobulin domain [PF13895.8, score=40.5]; Immunoglobulin domain [PF00047.27, score=40.3]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=26.4]} {Human: ENSG00000184144, CNTN2, contactin 2, [Score=57.4, Expect=5e-08]} {Mouse: ENSMUSG00000053024, Cntn2, contactin 2, [Score=55.5, Expect=1e-07]; ENSMUSG00000020674, Pxdn, peroxidasin, [Score=53.9, Expect=5e-07]; ENSMUSG00000061751, Kalrn, kalirin, RhoGEF kinase, [Score=53.5, Expect=6e-07]; ENSMUSG00000055022, Cntn1, contactin 1, [Score=52.8, Expect=1e-06]; ENSMUSG00000030075, Cntn3, contactin 3, [Score=52.8, Expect=1e-06]} {Dmel: FBgn0264975, Nrg, Neuroglian, [Score=55.5, Expect=1e-07]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [RH, Score=99.8, Expect=1e-22]} {RNA1509_60115} {RNA1310_31768} {RNA815_19521}
51. MligTC455_19410 194 4.04 Mlig455_047838

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.170

Region-enriched R2: 5.689/0.00000

2.486 - - 0.950 - 0.709 0.827 Mlig455_047838 {REF} {Length: 724} {TRANSSPLICED} {RNA1509_54915} {RNA1310_53549} {RNA815_27051}
52. MligTC455_39894 42 0.88 Mlig455_045042

Neo: -

Age: Down-Down-Up

2.442 - - 0.740 - 0.960 0.742 Mlig455_045042 {REF} {Length: 1959} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=34.4]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=28.6]} {Smed: dd_Smed_v6_56224_0_1, dd_Smed_v6_56224_0_1, [Score=48.9, Expect=1e-06]} {RNA1310_63008}
53. MligTC455_51288 32 0.66 Mlig455_033307

Neo: -

Age: -

NRG2 2.39 - - 0.721 - 0.955 0.714 Mlig455_033307 {REF} {Length: 1876} {TRANSSPLICED} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=62.6]; Immunoglobulin domain [PF13927.8, score=57.8]; Immunoglobulin domain [PF00047.27, score=52.9]; Immunoglobulin domain [PF13895.8, score=42.7]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=21.9]; Immunoglobulin V-set domain [PF07686.19, score=21.5]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=78.6, Expect=9e-15]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [Score=79.3, Expect=5e-15]} {Dmel: FBgn0003984, vn, vein, [RH, Score=79.3, Expect=3e-15]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=58.5, Expect=1e-08]} {Smed: dd_Smed_v6_16809_0_1, dd_Smed_v6_16809_0_1, [RH, Score=77.8, Expect=3e-15]} {RNA1310_26045.2} {RNA815_30218}
54. MligTC455_51881 14 0.3 Mlig455_047149, Mlig455_047294

Neo: -

Age: -

CHAC1 1.935 - - 0.990 - 0.945 -

Mlig455_047149 {REF} {Length: 1045} {Pfam: ChaC-like protein [PF04752.14, score=137.0]} {Human: ENSG00000128965, CHAC1, ChaC glutathione specific gamma-glutamylcyclotransferase 1, [Score=134, Expect=5e-39]} {Mouse: ENSMUSG00000027313, Chac1, ChaC, cation transport regulator 1, [Score=133, Expect=1e-38]} {Dmel: FBgn0039109, CG10365, [Score=112, Expect=5e-30]} {Celegans: WBGene00017724, F22F7.7, Gamma-glutamylcyclotransferase, [Score=108, Expect=9e-30]} {Smed: dd_Smed_v6_2439_0_1, dd_Smed_v6_2439_0_1, [Score=155, Expect=1e-47]} {RNA1310_83351}

Mlig455_047294 {REF} {Length: 1073} {Pfam: ChaC-like protein [PF04752.14, score=166.0]} {Human: ENSG00000128965, CHAC1, ChaC glutathione specific gamma-glutamylcyclotransferase 1, [RH, Score=153, Expect=6e-46]} {Mouse: ENSMUSG00000027313, Chac1, ChaC, cation transport regulator 1, [RH, Score=150, Expect=6e-45]} {Dmel: FBgn0039109, CG10365, [Score=131, Expect=5e-37]} {Celegans: WBGene00017724, F22F7.7, Gamma-glutamylcyclotransferase, [RH, Score=126, Expect=9e-36]} {Smed: dd_Smed_v6_2439_0_1, dd_Smed_v6_2439_0_1, [Score=182, Expect=2e-57]} {RNA1310_83351}
55. MligTC455_54305 43 0.89 Mlig455_035878, Mlig455_035917

Neo: -

Age: -

ZC3H10 1.932 - - 0.972 - 0.960 -

Mlig455_035878 {REF} {Length: 2474} {tRNA: Val(CAC),pseudo, score=28.9} {Pfam: Zinc finger C-x8-C-x5-C-x3-H type (and similar) [PF00642.26, score=25.6]; CCCH-type zinc finger [PF18044.3, score=20.1]; Zinc-finger containing family [PF15663.7, score=19.3]; Mediator complex subunit 3 fungal [PF11593.10, score=18.0]} {Human: ENSG00000135482, ZC3H10, zinc finger CCCH-type containing 10, [Score=149, Expect=2e-40]} {Mouse: ENSMUSG00000039810, Zc3h10, zinc finger CCCH type containing 10, [Score=149, Expect=2e-40]} {Smed: dd_Smed_v6_7175_0_2, dd_Smed_v6_7175_0_2, [Score=119, Expect=4e-29]} {RNA1509_47157} {RNA1310_87786} {RNA815_46414}

Mlig455_035917 {REF} {Length: 2428} {tRNA: Val(CAC),pseudo, score=30.2} {Pfam: Zinc finger C-x8-C-x5-C-x3-H type (and similar) [PF00642.26, score=25.6]; CCCH-type zinc finger [PF18044.3, score=20.1]; Zinc-finger containing family [PF15663.7, score=19.3]; Mediator complex subunit 3 fungal [PF11593.10, score=18.0]} {Human: ENSG00000135482, ZC3H10, zinc finger CCCH-type containing 10, [Score=149, Expect=2e-40]} {Mouse: ENSMUSG00000039810, Zc3h10, zinc finger CCCH type containing 10, [Score=149, Expect=2e-40]} {Smed: dd_Smed_v6_7175_0_2, dd_Smed_v6_7175_0_2, [Score=119, Expect=4e-29]} {RNA1509_47157} {RNA1310_87786} {RNA815_46414}
56. MligTC455_28720 27 0.56 Mlig455_057010

Neo: -

Age: -

ASIC1 1.931 - - 0.988 - 0.943 - Mlig455_057010 {REF} {Length: 2468} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=174.8]} {Human: ENSG00000110881, ASIC1, acid sensing ion channel subunit 1, [Score=62.4, Expect=1e-09]} {Mouse: ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=63.2, Expect=4e-10]} {Celegans: WBGene00016063, delm-2, DEgenerin Linked to Mechanosensation, [Score=53.1, Expect=3e-07]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [Score=109, Expect=2e-25]} {RNA1310_71846} {RNA815_38264}
57. MligTC455_53658 41 0.86 Mlig455_070698

Neo: -

Age: Up-Down-Down

Region-enriched R2: 9.084/0.01491

1.931 - - 0.959 - 0.972 - Mlig455_070698 {REF} {Length: 1026} {RNA1509_40972} {RNA1310_35649.1} {RNA815_17004}
58. MligTC455_23220 56 1.18 Mlig455_060190

Neo: -

Age: -

ACKR3 1.93 - - 0.967 - 0.963 - Mlig455_060190 {REF} {Length: 2108} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=106.0]} {Human: ENSG00000144476, ACKR3, atypical chemokine receptor 3, [RH, Score=99.0, Expect=1e-22]} {Mouse: ENSMUSG00000026180, Cxcr2, chemokine (C-X-C motif) receptor 2, [Score=112, Expect=1e-27]} {Dmel: FBgn0266429, AstA-R1, Allatostatin A receptor 1, [Score=102, Expect=4e-24]} {Celegans: WBGene00021439, ckr-2, CholecystoKinin Receptor homolog; Cholecystokinin receptor 2 splice isoform b, [Score=68.2, Expect=2e-12]} {Smed: dd_Smed_v6_10325_0_1, dd_Smed_v6_10325_0_1, [Score=81.6, Expect=5e-17]} {RNA1310_66504} {RNA815_39432}
59. MligTC455_29261 34 0.71 Mlig455_024258

Neo: -

Age: -

1.926 - - 0.964 - 0.962 - Mlig455_024258 {REF} {Length: 1171} {RNA1509_25125} {RNA1310_234.1} {RNA815_23.1}
60. MligTC455_00067 6 0.13 Mlig455_035302

Neo: -

Age: -

1.924 - - 0.962 - 0.962 - Mlig455_035302 {REF} {Length: 1437}
61. MligTC455_15890 18 0.38 Mlig455_059636

Neo: -

Age: -

CD209 1.924 - - 0.979 - 0.945 - Mlig455_059636 {REF} {Length: 1223} {Pfam: Lectin C-type domain [PF00059.23, score=29.7]} {Human: ENSG00000090659, CD209, CD209 molecule, [Score=49.3, Expect=2e-06]} {Dmel: FBgn0040096, lectin-33A, [Score=48.9, Expect=6e-07]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=64.7, Expect=2e-12]} {RNA1509_20946} {RNA1310_53178} {RNA815_42043}
62. MligTC455_16236 30 0.62 Mlig455_010759

Neo: -

Age: -

HRH1 1.924 - - 0.990 - 0.934 - Mlig455_010759 {REF} {Length: 2245} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=249.7]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=58.5]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=36.8]; Olfactory receptor [PF13853.8, score=24.6]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=20.4]; Protein of unknown function (DUF4022) [PF13214.8, score=19.6]} {Human: ENSG00000196639, HRH1, histamine receptor H1, [Score=179, Expect=3e-49]; ENSG00000149295, DRD2, dopamine receptor D2, [Score=172, Expect=1e-46]} {Mouse: ENSMUSG00000032259, Drd2, dopamine receptor D2, [Score=172, Expect=3e-47]; ENSMUSG00000053004, Hrh1, histamine receptor H1, [Score=171, Expect=3e-46]; ENSMUSG00000046159, Chrm3, cholinergic receptor, muscarinic 3, cardiac, [Score=166, Expect=1e-43]} {Dmel: FBgn0053517, Dop2R, Dopamine 2-like receptor, [RH, Score=252, Expect=4e-73]} {Celegans: WBGene00001053, dop-2, D2-like dopamine receptor long variant; DOPamine receptor, [RH, Score=173, Expect=6e-46]} {Smed: dd_Smed_v6_34803_0_1, dd_Smed_v6_34803_0_1, [RH, Score=241, Expect=1e-75]} {RNA1509_32954} {RNA1310_36460} {RNA815_785}
63. MligTC455_07555 12 0.26 Mlig455_028021

Neo: -

Age: -

1.923 - - 0.946 - 0.977 - Mlig455_028021 {REF} {Length: 1905} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=33.9]} {Mouse: ENSMUSG00000020793, Galr2, galanin receptor 2, [Score=58.2, Expect=1e-08]} {Smed: dd_Smed_v6_7534_0_1, dd_Smed_v6_7534_0_1, [RH, Score=182, Expect=2e-52]}
64. MligTC455_15183 10 0.2 Mlig455_018461

Neo: -

Age: Down-Up-Down

SCNN1A 1.918 - - 0.964 - 0.954 - Mlig455_018461 {REF} {Length: 2620} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=183.7]} {Human: ENSG00000111319, SCNN1A, sodium channel epithelial 1 alpha subunit, [Score=67.8, Expect=4e-11]} {Mouse: ENSMUSG00000030340, Scnn1a, sodium channel, nonvoltage-gated 1 alpha, [Score=55.5, Expect=6e-08]} {Celegans: WBGene00009073, delm-1, DEgenerin Linked to Mechanosensation, [Score=68.9, Expect=5e-12]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [RH, Score=125, Expect=3e-30]} {RNA1310_11413} {RNA815_11497}
65. MligTC455_09442 12 0.24 Mlig455_065765

Neo: -

Age: -

GABBR2 1.914 - - 0.969 - 0.945 - Mlig455_065765 {REF} {Length: 2959} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=146.7]; Receptor family ligand binding region [PF01094.30, score=114.9]} {Human: ENSG00000136928, GABBR2, gamma-aminobutyric acid type B receptor subunit 2, [Score=285, Expect=7e-82]} {Mouse: ENSMUSG00000039809, Gabbr2, gamma-aminobutyric acid (GABA) B receptor, 2, [Score=280, Expect=4e-80]} {Dmel: FBgn0027575, GABA-B-R2, metabotropic GABA-B receptor subtype 2, [Score=239, Expect=2e-65]} {Celegans: WBGene00021528, gbb-1, GABA B receptor subunit; GABAB1 receptor subunit, [Score=222, Expect=1e-60]} {Smed: dd_Smed_v6_20665_0_1, dd_Smed_v6_20665_0_1, [Score=140, Expect=6e-34]} {RNA1509_58025} {RNA1310_57812} {RNA815_11540}
66. MligTC455_14872 28 0.58 Mlig455_064004, Mlig455_064044

Neo: -

Age: logFC(26M/2M)=1.526

CLCA1 1.914 - - - - 0.962 0.952

Mlig455_064004 {REF} {Length: 4380} {Pfam: von Willebrand factor type A domain [PF00092.30, score=55.0]; von Willebrand factor type A domain [PF13768.8, score=48.2]; von Willebrand factor type A domain [PF13519.8, score=47.8]; vWA found in TerF C terminus [PF10138.11, score=29.1]; VWA domain containing CoxE-like protein [PF05762.16, score=28.0]; Calcium-activated chloride channel N terminal [PF08434.13, score=19.9]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=150, Expect=1e-36]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=154, Expect=6e-38]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [Score=89.0, Expect=6e-18]} {RNA1509_43698} {RNA1310_4397} {RNA815_4081}

Mlig455_064044 {REF} {Length: 4389} {Pfam: von Willebrand factor type A domain [PF00092.30, score=57.6]; von Willebrand factor type A domain [PF13768.8, score=50.7]; von Willebrand factor type A domain [PF13519.8, score=47.7]; vWA found in TerF C terminus [PF10138.11, score=29.0]; VWA domain containing CoxE-like protein [PF05762.16, score=26.0]; Calcium-activated chloride channel N terminal [PF08434.13, score=24.0]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=157, Expect=9e-39]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=159, Expect=2e-39]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [Score=91.3, Expect=1e-18]} {RNA1509_43698} {RNA1310_4397, RNA1509_43698} {RNA1509_43698, RNA815_4081}
67. MligTC455_17286 18 0.37 Mlig455_062850, Mlig455_062932

Neo: -

Age: -

NPFFR2, QRFPR 1.908 - - 0.957 - 0.951 -

Mlig455_062850 {REF} {Length: 2774} {TRANSSPLICED} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=136.4]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=29.7]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=17.9]} {Human: ENSG00000186867, QRFPR, pyroglutamylated RFamide peptide receptor, [Score=132, Expect=1e-33]; ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=130, Expect=4e-33]} {Mouse: ENSMUSG00000031212, Pgr15l, G protein-coupled receptor 15-like, [Score=137, Expect=9e-36]} {Dmel: FBgn0004841, TkR86C, Tachykinin-like receptor at 86C, [Score=138, Expect=9e-36]} {Celegans: WBGene00022004, npr-22, NeuroPeptide Receptor family, [Score=95.1, Expect=4e-21]} {Smed: dd_Smed_v6_17752_0_1, dd_Smed_v6_17752_0_1, [Score=105, Expect=1e-24]} {RNA1310_125205}

Mlig455_062932 {REF} {Length: 1463} {TRANSSPLICED} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=135.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=29.3]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=19.2]} {Human: ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=129, Expect=7e-33]; ENSG00000186867, QRFPR, pyroglutamylated RFamide peptide receptor, [Score=128, Expect=2e-32]} {Mouse: ENSMUSG00000031212, Pgr15l, G protein-coupled receptor 15-like, [Score=138, Expect=8e-36]} {Dmel: FBgn0004841, TkR86C, Tachykinin-like receptor at 86C, [Score=136, Expect=4e-35]} {Celegans: WBGene00022004, npr-22, NeuroPeptide Receptor family, [Score=95.1, Expect=4e-21]} {Smed: dd_Smed_v6_17752_0_1, dd_Smed_v6_17752_0_1, [Score=105, Expect=1e-24]} {RNA1310_125205}
68. MligTC455_05183 13 0.27 Mlig455_003637

Neo: -

Age: -

1.905 - - 0.960 - 0.945 - Mlig455_003637 {REF} {Length: 906} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_38541_0_1, dd_Smed_v6_38541_0_1, [Score=57.0, Expect=8e-10]} {RNA1310_45613} {RNA815_17816.1}
69. MligTC455_49819 27 0.55 Mlig455_007230

Neo: -

Age: Up-Down-Down

1.903 - - 0.962 - 0.941 - Mlig455_007230 {REF} {Length: 4542} {Pfam: Transferrin receptor-like dimerisation domain [PF04253.17, score=19.5]} {Mouse: ENSMUSG00000054999, Naaladl1, N-acetylated alpha-linked acidic dipeptidase-like 1, [Score=59.7, Expect=9e-09]} {RNA1310_53527} {RNA815_58531}
70. MligTC455_12867 14 0.29 Mlig455_049571

Neo: -

Age: -

KCNIP3 1.902 - - 0.949 - 0.953 - Mlig455_049571 {REF} {Length: 1857} {Pfam: EF-hand domain pair [PF13499.8, score=50.8]; EF hand [PF00036.34, score=44.5]; EF-hand domain [PF13405.8, score=39.6]; EF-hand domain pair [PF13833.8, score=32.7]; EF hand [PF13202.8, score=30.8]} {Human: ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=155, Expect=4e-44]; ENSG00000120049, KCNIP2, potassium voltage-gated channel interacting protein 2, [Score=148, Expect=1e-41]} {Mouse: ENSMUSG00000025221, Kcnip2, Kv channel-interacting protein 2, [Score=146, Expect=4e-41]; ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=140, Expect=7e-39]} {Dmel: FBgn0265595, CG44422, [Score=154, Expect=3e-42]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=125, Expect=1e-33]} {Smed: dd_Smed_v6_9434_0_1, dd_Smed_v6_9434_0_1, [Score=127, Expect=2e-34]} {RNA1310_70106} {RNA815_36691}
71. MligTC455_26200 12 0.26 Mlig455_068734

Neo: -

Age: -

TNXB 1.902 - - 0.957 - 0.945 - Mlig455_068734 {REF} {Length: 1237} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=176.4]} {Human: ENSG00000229353, TNXB, tenascin XB, [RH, Score=133, Expect=3e-34]; ENSG00000236236, TNXB, tenascin XB, [RH, Score=132, Expect=6e-34]; ENSG00000168477, TNXB, tenascin XB, [RH, Score=132, Expect=6e-34]} {Mouse: ENSMUSG00000033327, Tnxb, tenascin XB, [Score=131, Expect=8e-34]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=129, Expect=5e-34]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=128, Expect=1e-33]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=127, Expect=5e-33]} {Dmel: FBgn0033312, CG8642, [Score=110, Expect=2e-27]} {Celegans: WBGene00020516, T15B7.1, [Score=61.6, Expect=1e-10]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=113, Expect=4e-28]} {RNA1310_44670.1} {RNA815_23388}
72. MligTC455_27678 355 7.4 Mlig455_070610

Neo: -

Age: -

Region-specific R2: 4.724

Region-enriched R2: 3.766/0.00062

1.901 - - 0.961 - 0.940 - Mlig455_070610 {REF} {Length: 725} {RNA1509_17468, RNA1509_34237} {RNA1310_59474, RNA1509_17468, RNA1509_34237} {RNA1509_17468, RNA1509_34237, RNA815_28024}
73. MligTC455_33440 62 1.29 Mlig455_053806, Mlig455_053807

Neo: -

Age: Up-Down-Down

Region-enriched R2: 5.142/0.02950

GRID1 1.901 - - - - 0.952 0.949

Mlig455_053806 {REF} {Length: 3070} {Pfam: Ligand-gated ion channel [PF00060.28, score=72.9]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=46.7]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=39.8]; Receptor family ligand binding region [PF01094.30, score=28.6]} {Human: ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=145, Expect=2e-35]} {Mouse: ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=143, Expect=2e-34]} {Dmel: FBgn0038837, CG3822, [Score=126, Expect=2e-29]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=112, Expect=3e-25]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=257, Expect=1e-77]} {RNA1310_13880.2} {RNA815_12458}

Mlig455_053807 {REF} {Length: 3142} {Pfam: Ligand-gated ion channel [PF00060.28, score=79.5]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=46.3]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=38.3]; Receptor family ligand binding region [PF01094.30, score=36.5]} {Human: ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=139, Expect=2e-33]} {Mouse: ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=137, Expect=1e-32]} {Dmel: FBgn0038837, CG3822, [Score=125, Expect=5e-29]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=117, Expect=1e-26]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=259, Expect=2e-78]} {RNA1310_13880.2} {RNA815_12458}
74. MligTC455_18955 13 0.27 Mlig455_047126

Neo: -

Age: -

1.899 - - 0.964 - 0.935 - Mlig455_047126 {REF} {Length: 1058}
75. MligTC455_46543 178 3.7 Mlig455_000344, Mlig455_067946

Neo: -

Age: -

Region-specific R2: 6.098

Region-enriched R2: 6.851/0.00000

1.895 - - 0.952 - 0.943 -

Mlig455_000344 {REF} {Length: 1920} {RNA1310_82457} {RNA815_33120}

Mlig455_067946 {REF} {Length: 1217} {RNA1310_99435}
76. MligTC455_14172 11 0.22 Mlig455_042536

Neo: -

Age: -

STON2 1.894 - - 0.957 - 0.937 - Mlig455_042536 {REF} {Length: 4650} {Pfam: Adaptor complexes medium subunit family [PF00928.23, score=54.1]} {Human: ENSG00000140022, STON2, stonin 2, [Score=131, Expect=3e-30]} {Mouse: ENSMUSG00000020961, Ston2, stonin 2, [Score=132, Expect=1e-30]} {Dmel: FBgn0016975, stnB, stoned B, [Score=142, Expect=6e-34]} {Celegans: WBGene00006777, unc-41, Putative stoned B-like protein, [Score=155, Expect=6e-38]} {Smed: dd_Smed_v6_6859_0_1, dd_Smed_v6_6859_0_1, [Score=221, Expect=2e-58]} {RNA1310_91122}
77. MligTC455_01243 37 0.77 Mlig455_055650

Neo: -

Age: -

1.893 - - 0.920 - 0.973 - Mlig455_055650 {REF} {Length: 625} {Pfam: Universal stress protein family [PF00582.28, score=20.0]} {RNA1310_33871} {RNA815_28361}
78. MligTC455_44578 12 0.24 Mlig455_048995

Neo: Int S/G2/M

Age: -

Region-enriched R2: 5.730/0.04221

1.893 - - 0.954 - - 0.939 Mlig455_048995 {REF} {Length: 2090} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=110.0]} {RNA1310_22174} {RNA815_24783}
79. MligTC455_12152 19 0.39 Mlig455_066811

Neo: -

Age: -

GPRIN2 1.892 - - 0.983 - 0.909 - Mlig455_066811 {REF} {Length: 1594} {Pfam: G protein-regulated inducer of neurite outgrowth C-terminus [PF15235.8, score=49.2]} {Human: ENSG00000204175, GPRIN2, G protein regulated inducer of neurite outgrowth 2, [RH, Score=55.8, Expect=1e-07]} {Mouse: ENSMUSG00000071531, Gprin2, G protein regulated inducer of neurite outgrowth 2, [RH, Score=53.9, Expect=2e-07]; ENSMUSG00000069227, Gprin1, G protein-regulated inducer of neurite outgrowth 1, [RH, Score=53.9, Expect=3e-07]; ENSMUSG00000045441, Gprin3, GPRIN family member 3, [RH, Score=52.0, Expect=1e-06]} {Smed: dd_Smed_v6_10294_0_1, dd_Smed_v6_10294_0_1, [RH, Score=87.8, Expect=2e-18]} {RNA1310_92598} {RNA815_63284}
80. MligTC455_20643 34 0.72 Mlig455_066722

Neo: -

Age: -

CHRNA6 1.89 - - 0.966 - 0.924 - Mlig455_066722 {REF} {Length: 3504} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=224.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=197.3]} {Human: ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=357, Expect=6e-118]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=355, Expect=6e-117]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=352, Expect=1e-115]; ENSG00000169684, CHRNA5, cholinergic receptor nicotinic alpha 5 subunit, [Score=340, Expect=1e-111]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=340, Expect=1e-111]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=358, Expect=2e-118]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=355, Expect=3e-117]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=345, Expect=4e-113]; ENSMUSG00000027950, Chrnb2, cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal), [Score=341, Expect=1e-111]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=435, Expect=1e-148]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=371, Expect=8e-124]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=570, Expect=0.0]} {RNA1509_52151} {RNA1310_16118} {RNA815_53101}
81. MligTC455_33939 15 0.31 Mlig455_018477

Neo: Int S/G2/M

Age: Up-Down-Down, logFC(26M/2M)=-0.565

GUCY1B1 1.89 - - 0.929 - 0.961 - Mlig455_018477 {REF} {Length: 4178} {Pfam: Heme NO binding associated [PF07701.16, score=239.0]; Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=198.0]; Haem-NO-binding [PF07700.17, score=172.7]} {Human: ENSG00000061918, GUCY1B1, guanylate cyclase 1 soluble subunit beta 1, [Score=343, Expect=9e-106]} {Mouse: ENSMUSG00000021933, Gucy1b2, guanylate cyclase 1, soluble, beta 2, [Score=350, Expect=4e-106]; ENSMUSG00000028005, Gucy1b1, guanylate cyclase 1, soluble, beta 1, [Score=348, Expect=7e-108]} {Dmel: FBgn0038295, Gyc88E, Guanylyl cyclase at 88E, [RH, Score=622, Expect=0.0]} {Celegans: WBGene00001551, gcy-31, Soluble guanylate cyclase gcy-31, [RH, Score=530, Expect=2e-176]} {Smed: dd_Smed_v6_18111_0_1, dd_Smed_v6_18111_0_1, [RH, Score=818, Expect=0.0]} {RNA1509_41885} {RNA1310_21359} {RNA815_6599.2}
82. MligTC455_35813 35 0.73 Mlig455_013562, Mlig455_013615

Neo: -

Age: -

Region-enriched R2: 7.733/0.00085

NPR2 1.889 - - 0.961 - 0.928 -

Mlig455_013562 {REF} {Length: 3105} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=187.6]; Nitrate and nitrite sensing [PF08376.12, score=108.9]; Heme NO binding associated [PF07701.16, score=29.1]} {Human: ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=251, Expect=2e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=247, Expect=6e-69]; ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=241, Expect=1e-66]} {Mouse: ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=252, Expect=1e-73]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=248, Expect=2e-69]} {Dmel: FBgn0053958, CG33958, [Score=330, Expect=3e-102]} {Celegans: WBGene00001533, gcy-6, Receptor-type guanylate cyclase gcy-6, [Score=231, Expect=7e-64]} {Smed: dd_Smed_v6_11767_0_1, dd_Smed_v6_11767_0_1, [Score=244, Expect=3e-68]} {RNA1310_16282} {RNA815_27869}

Mlig455_013615 {REF} {Length: 2993} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=187.7]; Nitrate and nitrite sensing [PF08376.12, score=109.5]; Heme NO binding associated [PF07701.16, score=29.1]} {Human: ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=251, Expect=2e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=246, Expect=8e-69]; ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=241, Expect=1e-66]} {Mouse: ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=252, Expect=9e-74]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=247, Expect=2e-69]} {Dmel: FBgn0053958, CG33958, [Score=331, Expect=1e-102]} {Celegans: WBGene00001533, gcy-6, Receptor-type guanylate cyclase gcy-6, [Score=231, Expect=8e-64]} {Smed: dd_Smed_v6_11767_0_1, dd_Smed_v6_11767_0_1, [Score=244, Expect=3e-68]} {RNA1310_16282} {RNA815_33407}
83. MligTC455_40051 36 0.76 Mlig455_025990

Neo: -

Age: logFC(26M/2M)=-0.633

PRKCE 1.889 - - 0.955 - 0.934 - Mlig455_025990 {REF} {Length: 2622} {Pfam: Protein kinase domain [PF00069.27, score=102.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=69.5]; Kinase-like [PF14531.8, score=19.5]} {Human: ENSG00000171132, PRKCE, protein kinase C epsilon, [Score=84.3, Expect=1e-16]} {Mouse: ENSMUSG00000045038, Prkce, protein kinase C, epsilon, [Score=82.0, Expect=5e-16]} {Dmel: FBgn0283472, S6k, Ribosomal protein S6 kinase, [Score=79.0, Expect=2e-15]} {Celegans: WBGene00009793, pkn-1, Protein Kinase N (PKN) homolog, [Score=73.2, Expect=2e-13]} {Smed: dd_Smed_v6_8010_0_1, dd_Smed_v6_8010_0_1, [Score=77.8, Expect=4e-15]} {RNA1509_36146} {RNA1310_24732} {RNA815_64704}
84. MligTC455_44954 1303 27.14 Mlig455_029595, Mlig455_070648

Neo: Int S/G2/M

Age: Down-Up-Up, logFC(26M/2M)=1.023

Region-specific R2: 8.846

Region-enriched R2: 10.764/0.00000

1.889 - - 0.964 - 0.925 -

Mlig455_029595 {REF} {Length: 484} {Pfam: Pancreatic hormone peptide [PF00159.20, score=30.3]} {Smed: dd_Smed_v6_6375_0_1, dd_Smed_v6_6375_0_1, [RH, Score=47.4, Expect=3e-08]} {RNA1509_20871} {RNA1310_66833.2} {RNA815_41767}

Mlig455_070648 {REF} {Length: 484} {Pfam: Pancreatic hormone peptide [PF00159.20, score=30.3]} {Smed: dd_Smed_v6_6375_0_1, dd_Smed_v6_6375_0_1, [RH, Score=47.4, Expect=3e-08]} {RNA1509_20871, RNA1509_39484} {RNA1310_66833.2, RNA1509_20871, RNA1509_39484} {RNA1509_20871, RNA1509_39484, RNA815_41767}
85. MligTC455_48692 15 0.32 Mlig455_021398

Neo: -

Age: -

Region-enriched R2: 8.096/0.02429

1.889 - - 0.954 - 0.935 - Mlig455_021398 {REF} {Length: 1571} {Pfam: Ankyrin repeat [PF00023.32, score=20.9]; Ankyrin repeats (many copies) [PF13637.8, score=20.4]; Ankyrin repeats (many copies) [PF13857.8, score=19.6]; Ankyrin repeats (3 copies) [PF12796.9, score=19.4]} {Smed: dd_Smed_v6_29956_0_1, dd_Smed_v6_29956_0_1, [Score=54.7, Expect=3e-08]} {RNA1310_69005}
86. MligTC455_40199 64 1.33 Mlig455_026444, Mlig455_026477

Neo: -

Age: -

ASIC4 1.886 - - 0.935 - 0.951 -

Mlig455_026444 {REF} {Length: 2570} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=204.0]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=57.4, Expect=7e-08]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=53.9, Expect=5e-07]; ENSMUSG00000038276, Asic3, acid-sensing (proton-gated) ion channel 3, [Score=52.4, Expect=1e-06]} {Celegans: WBGene00003174, mec-10, Degenerin mec-10, [Score=69.7, Expect=5e-12]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=119, Expect=6e-28]} {RNA1310_21223} {RNA815_27174}

Mlig455_026477 {REF} {Length: 2402} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=160.5]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=57.0, Expect=8e-08]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=53.9, Expect=5e-07]} {Celegans: WBGene00003174, mec-10, Degenerin mec-10, [Score=69.3, Expect=5e-12]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=93.6, Expect=9e-20]} {RNA1310_21223} {RNA815_27174}
87. MligTC455_27216 56 1.18 Mlig455_022418

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.523

TRPM3 1.885 - - - - 0.996 0.889 Mlig455_022418 {REF} {Length: 4794} {Pfam: SLOG in TRPM [PF18139.3, score=136.8]; Ion transport protein [PF00520.33, score=41.0]; SLOG in TRPM, prokaryote [PF18171.3, score=34.2]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=317, Expect=2e-88]; ENSG00000119121, TRPM6, transient receptor potential cation channel subfamily M member 6, [Score=316, Expect=4e-88]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=319, Expect=4e-90]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=309, Expect=7e-88]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=255, Expect=4e-69]} {Smed: dd_Smed_v6_9288_0_1, dd_Smed_v6_9288_0_1, [Score=418, Expect=3e-126]} {RNA1509_17593} {RNA1310_1651, RNA1509_17593} {RNA1509_17593, RNA815_2281}
88. MligTC455_27785 115 2.39 Mlig455_001141

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.796

HMCN2 1.885 - - 0.913 - 0.972 - Mlig455_001141 {REF} {Length: 2156} {Pfam: von Willebrand factor type A domain [PF13519.8, score=54.7]; von Willebrand factor type A domain [PF13768.8, score=30.6]} {Human: ENSG00000148357, HMCN2, hemicentin 2, [Score=81.3, Expect=2e-15]} {Mouse: ENSMUSG00000007030, Vwa7, von Willebrand factor A domain containing 7, [Score=79.0, Expect=6e-15]; ENSMUSG00000055632, Hmcn2, hemicentin 2, [Score=77.8, Expect=2e-14]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=96.3, Expect=1e-20]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=79.7, Expect=2e-15]} {RNA1509_38050} {RNA1310_19586} {RNA815_17693}
89. MligTC455_27918 42 0.87 Mlig455_004025, Mlig455_004105, Mlig455_039294

Neo: -

Age: Down-Up-Up

1.885 - - 0.960 - 0.925 -

Mlig455_004025 {REF} {Length: 2650} {RNA1310_16141} {RNA815_7007}

Mlig455_004105 {REF} {Length: 1268} {RNA1310_85247} {RNA815_59251}

Mlig455_039294 {REF} {Length: 2639} {RNA1310_16141} {RNA815_7007}
90. MligTC455_19252 1355 28.24 Mlig455_054908, Mlig455_065614, Mlig455_065623

Neo: -

Age: Down-Down-Up

Region-enriched R2: 4.927/0.00706

QPCT 1.884 - - 0.920 - 0.964 -

Mlig455_054908 {REF} {Length: 1427} {Pfam: Peptidase family M28 [PF04389.19, score=84.4]} {Human: ENSG00000115828, QPCT, glutaminyl-peptide cyclotransferase, [Score=113, Expect=3e-28]} {Mouse: ENSMUSG00000030407, Qpctl, glutaminyl-peptide cyclotransferase-like, [Score=123, Expect=8e-32]} {Dmel: FBgn0052412, QC, Glutaminyl cyclase, [Score=116, Expect=7e-30]} {Celegans: WBGene00010418, H27A22.1, [Score=124, Expect=6e-33]} {Smed: dd_Smed_v6_4861_0_1, dd_Smed_v6_4861_0_1, [Score=118, Expect=1e-30]} {RNA1509_35784} {RNA1310_28475}

Mlig455_065614 {REF} {Length: 1515} {Pfam: Peptidase family M28 [PF04389.19, score=121.0]} {Human: ENSG00000115828, QPCT, glutaminyl-peptide cyclotransferase, [Score=157, Expect=2e-44]} {Mouse: ENSMUSG00000024084, Qpct, glutaminyl-peptide cyclotransferase (glutaminyl cyclase), [Score=162, Expect=2e-46]; ENSMUSG00000030407, Qpctl, glutaminyl-peptide cyclotransferase-like, [Score=161, Expect=6e-46]} {Dmel: FBgn0052412, QC, Glutaminyl cyclase, [Score=158, Expect=2e-45]} {Celegans: WBGene00010418, H27A22.1, [Score=166, Expect=2e-48]} {Smed: dd_Smed_v6_4861_0_1, dd_Smed_v6_4861_0_1, [Score=156, Expect=2e-44]} {RNA1509_35784} {RNA1310_28475, RNA1509_35784}

Mlig455_065623 {REF} {Length: 1295} {Pfam: Peptidase family M28 [PF04389.19, score=121.4]} {Human: ENSG00000115828, QPCT, glutaminyl-peptide cyclotransferase, [Score=158, Expect=6e-45]} {Mouse: ENSMUSG00000030407, Qpctl, glutaminyl-peptide cyclotransferase-like, [Score=162, Expect=2e-46]; ENSMUSG00000024084, Qpct, glutaminyl-peptide cyclotransferase (glutaminyl cyclase), [Score=161, Expect=3e-46]} {Dmel: FBgn0052412, QC, Glutaminyl cyclase, [Score=154, Expect=8e-44]} {Celegans: WBGene00010418, H27A22.1, [Score=163, Expect=2e-47]} {Smed: dd_Smed_v6_4861_0_1, dd_Smed_v6_4861_0_1, [Score=154, Expect=8e-44]} {RNA1509_35784} {RNA1310_28475}
91. MligTC455_44862 1318 27.47 Mlig455_028792

Neo: -

Age: -

Region-enriched R2: 3.389/0.00000

QPCT 1.884 - - 0.932 - 0.952 - Mlig455_028792 {REF} {Length: 1901} {Pfam: Peptidase family M28 [PF04389.19, score=137.7]} {Human: ENSG00000115828, QPCT, glutaminyl-peptide cyclotransferase, [RH, Score=189, Expect=5e-57]; ENSG00000011478, QPCTL, glutaminyl-peptide cyclotransferase like, [RH, Score=186, Expect=1e-55]} {Mouse: ENSMUSG00000030407, Qpctl, glutaminyl-peptide cyclotransferase-like, [RH, Score=190, Expect=3e-57]; ENSMUSG00000024084, Qpct, glutaminyl-peptide cyclotransferase (glutaminyl cyclase), [RH, Score=189, Expect=5e-57]} {Dmel: FBgn0036999, isoQC, iso Glutaminyl cyclase, [RH, Score=210, Expect=2e-65]} {Celegans: WBGene00010418, H27A22.1, [Score=182, Expect=5e-55]} {Smed: dd_Smed_v6_4861_0_2, dd_Smed_v6_4861_0_2, [Score=166, Expect=1e-48]} {RNA1509_15042, RNA1509_18145} {RNA1310_21749, RNA1509_15042, RNA1509_18145} {RNA1509_15042, RNA1509_18145, RNA815_8635.1}
92. MligTC455_15332 44 0.93 Mlig455_062622, Mlig455_067527

Neo: -

Age: -

Region-enriched R2: 7.516/0.00418

ASIC4 1.881 - - 0.951 - 0.930 -

Mlig455_062622 {REF} {Length: 2228} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=73.0]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=47.4, Expect=7e-06]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=51.6, Expect=2e-07]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=55.8, Expect=3e-09]} {Smed: dd_Smed_v6_19727_0_1, dd_Smed_v6_19727_0_1, [Score=53.1, Expect=2e-08]} {RNA1310_17847} {RNA815_27317}

Mlig455_067527 {REF} {Length: 1916} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=147.3]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=50.1, Expect=1e-05]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=50.8, Expect=3e-06]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=54.7, Expect=1e-07]} {Smed: dd_Smed_v6_19727_0_1, dd_Smed_v6_19727_0_1, [Score=53.5, Expect=2e-07]} {RNA1310_17847} {RNA815_27317}
93. MligTC455_52527 28 0.58 Mlig455_025836

Neo: -

Age: -

FLVCR2 1.881 - - 0.962 - 0.919 - Mlig455_025836 {REF} {Length: 2177} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=81.4]; Sugar (and other) transporter [PF00083.26, score=18.7]} {Human: ENSG00000119686, FLVCR2, feline leukemia virus subgroup C cellular receptor family member 2, [RH, Score=364, Expect=5e-119]} {Mouse: ENSMUSG00000034258, Flvcr2, feline leukemia virus subgroup C cellular receptor 2, [RH, Score=367, Expect=3e-120]} {Dmel: FBgn0033196, CG1358, [RH, Score=350, Expect=1e-114]} {Celegans: WBGene00015632, C09D4.1, Uncharacterized MFS-type transporter C09D4.1, [RH, Score=358, Expect=1e-116]} {Smed: dd_Smed_v6_7578_0_1, dd_Smed_v6_7578_0_1, [Score=335, Expect=3e-109]} {RNA1509_31725} {RNA1310_8852.1} {RNA815_14234}
94. MligTC455_06407 25 0.52 Mlig455_055014

Neo: -

Age: -

1.879 - - 0.964 - - 0.915 Mlig455_055014 {REF} {Length: 492} {NoTransDecoderORF}
95. MligTC455_12446 8 0.17 Mlig455_018624, Mlig455_018810

Neo: -

Age: -

CHRNA10, CHRNA7 1.879 - - - - 0.961 0.918

Mlig455_018624 {REF} {Length: 3606} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.6]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=112.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=72.0]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=143, Expect=2e-35]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=142, Expect=2e-35]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=140, Expect=1e-34]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=140, Expect=1e-34]; ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=136, Expect=2e-33]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=145, Expect=2e-36]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=141, Expect=3e-35]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=140, Expect=2e-35]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=139, Expect=2e-34]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=142, Expect=2e-34]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=144, Expect=3e-36]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=138, Expect=2e-34]} {RNA1509_9118} {RNA1310_65904} {RNA815_40596}

Mlig455_018810 {REF} {Length: 2717} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.6]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=112.8]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=72.2]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=141, Expect=2e-35]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=140, Expect=2e-34]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=139, Expect=2e-34]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=139, Expect=2e-34]; ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=138, Expect=4e-34]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=145, Expect=2e-36]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=141, Expect=2e-35]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=140, Expect=8e-35]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=140, Expect=7e-35]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=142, Expect=1e-34]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=144, Expect=4e-36]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=139, Expect=1e-34]} {RNA1509_9118} {RNA1310_84333} {RNA815_40596}
96. MligTC455_20890 29 0.6 Mlig455_001461

Neo: -

Age: Down-Down-Up

1.879 - - 0.972 - 0.907 - Mlig455_001461 {REF} {Length: 2259} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=39.9]} {Smed: dd_Smed_v6_42201_0_1, dd_Smed_v6_42201_0_1, [Score=87.4, Expect=6e-19]} {RNA1310_44182}
97. MligTC455_12525 11 0.23 Mlig455_067862

Neo: -

Age: -

1.878 - - 0.951 - 0.927 - Mlig455_067862 {REF} {Length: 1730} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=44.0]; TcdA/TcdB catalytic glycosyltransferase domain [PF12919.9, score=18.1]} {Smed: dd_Smed_v6_13661_0_2, dd_Smed_v6_13661_0_2, [Score=80.9, Expect=3e-17]} {RNA1509_20770} {RNA1310_58410} {RNA815_35907}
98. MligTC455_44956 144 2.99 Mlig455_061510

Neo: -

Age: -

1.878 - - 0.915 - 0.963 - Mlig455_061510 {REF} {Length: 493} {Pfam: Pancreatic hormone peptide [PF00159.20, score=31.3]} {Smed: dd_Smed_v6_6375_0_1, dd_Smed_v6_6375_0_1, [RH, Score=47.8, Expect=9e-09]} {RNA1509_17163} {RNA1310_66833.1} {RNA815_41767}
99. MligTC455_09874 31 0.65 Mlig455_045071

Neo: -

Age: -

DOC2A 1.877 - - 0.912 - 0.965 - Mlig455_045071 {REF} {Length: 1760} {Pfam: C2 domain [PF00168.32, score=55.9]} {Human: ENSG00000149927, DOC2A, double C2 domain alpha, [Score=55.8, Expect=7e-08]} {Mouse: ENSMUSG00000052301, Doc2a, double C2, alpha, [Score=55.5, Expect=7e-08]} {Celegans: WBGene00004923, snt-3, SyNapTotagmin, [Score=70.5, Expect=2e-13]} {Smed: dd_Smed_v6_16731_0_1, dd_Smed_v6_16731_0_1, [Score=112, Expect=7e-27]} {RNA1310_36283} {RNA815_40844}
100. MligTC455_53827 41 0.85 Mlig455_057728

Neo: -

Age: -

Region-enriched R2: 6.363/0.00033
Region-enriched R4: 3.785/0.00394

1.877 - - 0.890 - 0.987 - Mlig455_057728 {REF} {Length: 1074} {RNA1310_41119} {RNA815_15825}

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