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Results for MligTC455_25619

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_25619 687 14.32 Mlig455_005012, Mlig455_005054, Mlig455_005259

Neo: -

Age: Up-Down-Down

LRRK2

Mlig455_005012 {REF} {Length: 9598} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=121.0]; Ankyrin repeats (3 copies) [PF12796.9, score=105.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=102.3]; Ankyrin repeats (many copies) [PF13637.8, score=84.7]; C-terminal of Roc, COR, domain [PF16095.7, score=75.8]; Ankyrin repeats (many copies) [PF13857.8, score=75.6]; Leucine rich repeat [PF13855.8, score=74.7]; Ankyrin repeat [PF13606.8, score=74.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=73.8]; Leucine Rich repeats (2 copies) [PF12799.9, score=68.1]; Ankyrin repeat [PF00023.32, score=42.8]; Ras family [PF00071.24, score=33.7]; Leucine Rich Repeat [PF00560.35, score=21.1]; ADP-ribosylation factor family [PF00025.23, score=18.6]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=204, Expect=1e-51]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=203, Expect=1e-51]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [RH, Score=488, Expect=7e-139]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [RH, Score=301, Expect=2e-81]} {Smed: dd_Smed_v6_7343_0_2, dd_Smed_v6_7343_0_2, [Score=145, Expect=2e-34]} {RNA1509_53069, RNA1509_5682} {RNA1310_445.1, RNA1509_53069} {RNA1509_53069, RNA815_1059}

Mlig455_005054 {REF} {Length: 9596} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=121.0]; Ankyrin repeats (3 copies) [PF12796.9, score=106.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=102.3]; Ankyrin repeats (many copies) [PF13637.8, score=85.1]; Ankyrin repeat [PF13606.8, score=77.0]; Ankyrin repeats (many copies) [PF13857.8, score=76.6]; C-terminal of Roc, COR, domain [PF16095.7, score=76.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=73.8]; Leucine rich repeat [PF13855.8, score=72.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=64.3]; Ankyrin repeat [PF00023.32, score=44.3]; Ras family [PF00071.24, score=33.7]; Leucine Rich Repeat [PF00560.35, score=21.0]; ADP-ribosylation factor family [PF00025.23, score=18.7]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=204, Expect=1e-51]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=202, Expect=2e-51]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [RH, Score=486, Expect=3e-138]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [RH, Score=299, Expect=6e-81]} {Smed: dd_Smed_v6_7343_0_1, dd_Smed_v6_7343_0_1, [Score=145, Expect=2e-34]} {RNA1509_5682} {RNA1310_445.1, RNA1509_5682} {RNA1509_5682, RNA815_1059}

Mlig455_005259 {REF} {Length: 11838} {Pfam: Protein kinase domain [PF00069.27, score=120.5]; Ankyrin repeats (3 copies) [PF12796.9, score=105.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=101.7]; Ankyrin repeats (many copies) [PF13637.8, score=82.1]; Ankyrin repeats (many copies) [PF13857.8, score=76.0]; Ankyrin repeat [PF13606.8, score=75.5]; C-terminal of Roc, COR, domain [PF16095.7, score=75.5]; Leucine rich repeat [PF13855.8, score=73.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=73.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=67.1]; Ankyrin repeat [PF00023.32, score=42.8]; Ras family [PF00071.24, score=33.3]; Leucine Rich Repeat [PF00560.35, score=19.4]; ADP-ribosylation factor family [PF00025.23, score=18.3]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=202, Expect=8e-51]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=201, Expect=6e-51]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [RH, Score=489, Expect=8e-139]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [RH, Score=295, Expect=9e-80]} {Smed: dd_Smed_v6_7343_0_2, dd_Smed_v6_7343_0_2, [Score=143, Expect=1e-33]} {RNA1509_5682} {RNA1310_445.1} {RNA815_1059}

Cumulative graph for MligTC455_25619

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.737 4.1 0.62761 1.00000
RegionR2 0.899 4.1 0.18308 0.53432
RegionR3 -0.605 4.1 0.28864 0.83154
RegionR4 0.308 4.1 0.64673 0.95036
RegionR5 -0.003 4.1 0.99751 1.00000
RegionR6 -0.277 4.1 0.61835 1.00000
RegionR7 0.331 4.1 0.58956 1.00000
RegionR8 0.084 4.1 0.91663 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 3.132 4.1 0.03848 0.65989
RegenerationR2 -0.178 4.1 0.74856 0.97288
RegenerationR3 1.246 4.1 0.06041 0.41862
RegenerationR4 -0.1 4.1 0.88257 1.00000
RegenerationR5 0.116 4.1 0.84825 1.00000
RegenerationR6 1.033 4.1 0.10651 0.40431
RegenerationBL -0.474 4.1 0.52369 0.88479
RegenerationTP -0.077 4.1 0.91911 1.00000


Genes with expression patterns similar to MligTC455_25619

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_25619 687 14.32 Mlig455_005012, Mlig455_005054, Mlig455_005259

Neo: -

Age: Up-Down-Down

LRRK2 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_005012 {REF} {Length: 9598} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=121.0]; Ankyrin repeats (3 copies) [PF12796.9, score=105.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=102.3]; Ankyrin repeats (many copies) [PF13637.8, score=84.7]; C-terminal of Roc, COR, domain [PF16095.7, score=75.8]; Ankyrin repeats (many copies) [PF13857.8, score=75.6]; Leucine rich repeat [PF13855.8, score=74.7]; Ankyrin repeat [PF13606.8, score=74.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=73.8]; Leucine Rich repeats (2 copies) [PF12799.9, score=68.1]; Ankyrin repeat [PF00023.32, score=42.8]; Ras family [PF00071.24, score=33.7]; Leucine Rich Repeat [PF00560.35, score=21.1]; ADP-ribosylation factor family [PF00025.23, score=18.6]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=204, Expect=1e-51]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=203, Expect=1e-51]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [RH, Score=488, Expect=7e-139]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [RH, Score=301, Expect=2e-81]} {Smed: dd_Smed_v6_7343_0_2, dd_Smed_v6_7343_0_2, [Score=145, Expect=2e-34]} {RNA1509_53069, RNA1509_5682} {RNA1310_445.1, RNA1509_53069} {RNA1509_53069, RNA815_1059}

Mlig455_005054 {REF} {Length: 9596} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=121.0]; Ankyrin repeats (3 copies) [PF12796.9, score=106.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=102.3]; Ankyrin repeats (many copies) [PF13637.8, score=85.1]; Ankyrin repeat [PF13606.8, score=77.0]; Ankyrin repeats (many copies) [PF13857.8, score=76.6]; C-terminal of Roc, COR, domain [PF16095.7, score=76.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=73.8]; Leucine rich repeat [PF13855.8, score=72.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=64.3]; Ankyrin repeat [PF00023.32, score=44.3]; Ras family [PF00071.24, score=33.7]; Leucine Rich Repeat [PF00560.35, score=21.0]; ADP-ribosylation factor family [PF00025.23, score=18.7]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=204, Expect=1e-51]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=202, Expect=2e-51]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [RH, Score=486, Expect=3e-138]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [RH, Score=299, Expect=6e-81]} {Smed: dd_Smed_v6_7343_0_1, dd_Smed_v6_7343_0_1, [Score=145, Expect=2e-34]} {RNA1509_5682} {RNA1310_445.1, RNA1509_5682} {RNA1509_5682, RNA815_1059}

Mlig455_005259 {REF} {Length: 11838} {Pfam: Protein kinase domain [PF00069.27, score=120.5]; Ankyrin repeats (3 copies) [PF12796.9, score=105.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=101.7]; Ankyrin repeats (many copies) [PF13637.8, score=82.1]; Ankyrin repeats (many copies) [PF13857.8, score=76.0]; Ankyrin repeat [PF13606.8, score=75.5]; C-terminal of Roc, COR, domain [PF16095.7, score=75.5]; Leucine rich repeat [PF13855.8, score=73.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=73.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=67.1]; Ankyrin repeat [PF00023.32, score=42.8]; Ras family [PF00071.24, score=33.3]; Leucine Rich Repeat [PF00560.35, score=19.4]; ADP-ribosylation factor family [PF00025.23, score=18.3]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=202, Expect=8e-51]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=201, Expect=6e-51]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [RH, Score=489, Expect=8e-139]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [RH, Score=295, Expect=9e-80]} {Smed: dd_Smed_v6_7343_0_2, dd_Smed_v6_7343_0_2, [Score=143, Expect=1e-33]} {RNA1509_5682} {RNA1310_445.1} {RNA815_1059}
2. MligTC455_15069 79 1.64 Mlig455_029537, Mlig455_043002, Mlig455_043055

Neo: -

Age: -

NPFFR1, NPFFR2 2.692 - - 0.913 0.793 0.986 -

Mlig455_029537 {REF} {Length: 3225} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=88.5]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=67.9]} {Human: ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=58.2, Expect=2e-08]; ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=57.0, Expect=4e-08]} {Mouse: ENSMUSG00000038760, Trhr, thyrotropin releasing hormone receptor, [Score=57.8, Expect=1e-08]} {Dmel: FBgn0029768, SPR, Sex peptide receptor, [Score=145, Expect=3e-38]} {Celegans: WBGene00010986, sprr-1, Sex Peptide Receptor (Drosophila) Related, [Score=153, Expect=1e-40]} {Smed: dd_Smed_v6_25066_0_1, dd_Smed_v6_25066_0_1, [RH, Score=187, Expect=2e-54]} {RNA1310_36664} {RNA815_35786}

Mlig455_043002 {REF} {Length: 3511} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=87.7]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=68.0]} {Human: ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=58.2, Expect=2e-08]} {Mouse: ENSMUSG00000038760, Trhr, thyrotropin releasing hormone receptor, [Score=57.0, Expect=2e-08]} {Dmel: FBgn0029768, SPR, Sex peptide receptor, [Score=145, Expect=1e-38]} {Celegans: WBGene00010986, sprr-1, Sex Peptide Receptor (Drosophila) Related, [Score=149, Expect=1e-39]} {Smed: dd_Smed_v6_25066_0_1, dd_Smed_v6_25066_0_1, [RH, Score=187, Expect=7e-55]} {RNA1310_36664} {RNA815_35786}

Mlig455_043055 {REF} {Length: 5068} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=55.1]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=44.4]} {Human: ENSG00000148734, NPFFR1, neuropeptide FF receptor 1, [Score=55.5, Expect=8e-08]; ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=53.5, Expect=3e-07]} {Mouse: ENSMUSG00000020090, Npffr1, neuropeptide FF receptor 1, [Score=54.3, Expect=1e-07]} {Dmel: FBgn0029768, SPR, Sex peptide receptor, [Score=81.6, Expect=1e-16]} {Celegans: WBGene00010986, sprr-1, Sex Peptide Receptor (Drosophila) Related, [Score=97.1, Expect=8e-22]} {Smed: dd_Smed_v6_25066_0_1, dd_Smed_v6_25066_0_1, [Score=122, Expect=3e-31]} {RNA1310_36664} {RNA815_35786}
3. MligTC455_24752 42 0.88 Mlig455_016697

Neo: -

Age: -

1.903 - - 0.931 - 0.972 - Mlig455_016697 {REF} {Length: 1586} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1310_47779} {RNA815_39270}
4. MligTC455_35693 75 1.57 Mlig455_041528, Mlig455_069395

Neo: -

Age: -

NPSR1 1.879 - - 0.902 - 0.977 -

Mlig455_041528 {REF} {Length: 1601} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=138.8]} {Human: ENSG00000187258, NPSR1, neuropeptide S receptor 1, [Score=100, Expect=9e-23]} {Mouse: ENSMUSG00000043659, Npsr1, neuropeptide S receptor 1, [Score=95.9, Expect=3e-21]} {Dmel: FBgn0036278, CrzR, Corazonin receptor, [RH, Score=154, Expect=4e-41]} {Celegans: WBGene00018798, gnrr-1, GoNadotropin-Releasing hormone Receptor (GnRHR) related, [Score=102, Expect=1e-23]} {Smed: dd_Smed_v6_33148_0_1, dd_Smed_v6_33148_0_1, [RH, Score=113, Expect=5e-28]} {RNA1310_37338} {RNA815_25753}

Mlig455_069395 {REF} {Length: 4341} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=139.5]} {Human: ENSG00000187258, NPSR1, neuropeptide S receptor 1, [Score=102, Expect=3e-23]} {Mouse: ENSMUSG00000043659, Npsr1, neuropeptide S receptor 1, [Score=97.1, Expect=1e-21]} {Dmel: FBgn0036278, CrzR, Corazonin receptor, [RH, Score=155, Expect=4e-41]} {Celegans: WBGene00018798, gnrr-1, GoNadotropin-Releasing hormone Receptor (GnRHR) related, [Score=102, Expect=1e-23]} {Smed: dd_Smed_v6_33148_0_1, dd_Smed_v6_33148_0_1, [RH, Score=114, Expect=3e-28]} {RNA1509_54184} {RNA1310_37338} {RNA815_25753}
5. MligTC455_37990 53 1.11 Mlig455_008621

Neo: -

Age: -

1.877 - - 0.919 - 0.958 - Mlig455_008621 {REF} {Length: 2347} {Pfam: EF-hand domain pair [PF13499.8, score=32.3]; EF-hand domain [PF13405.8, score=26.8]; EF hand [PF00036.34, score=25.2]; EF hand [PF13202.8, score=19.4]; EF-hand domain pair [PF13833.8, score=19.2]} {Smed: dd_Smed_v6_1010_0_1, dd_Smed_v6_1010_0_1, [Score=78.6, Expect=3e-17]} {RNA1310_31713.1} {RNA815_36423}
6. MligTC455_35460 218 4.53 Mlig455_041682

Neo: Irradiation

Age: -

1.837 - - - 0.851 0.986 - Mlig455_041682 {REF} {Length: 2105} {TRANSSPLICED} {RNA1509_45996} {RNA1310_21160.1, RNA1509_45996} {RNA1509_45996, RNA815_10651.1}
7. MligTC455_19610 189 3.95 Mlig455_029340

Neo: -

Age: -

1.823 - - 0.842 - 0.981 - Mlig455_029340 {REF} {Length: 5127} {RNA1509_27135, RNA1509_29384, RNA1509_40464} {RNA1310_1522.1, RNA1509_27135, RNA1509_29384, RNA1509_40464} {RNA1509_27135, RNA1509_29384, RNA1509_40464, RNA815_3707}
8. MligTC455_35461 195 4.06 Mlig455_041760

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.579

1.81 - - - 0.822 0.988 - Mlig455_041760 {REF} {Length: 1159} {RNA1509_45996} {RNA1310_21160.1} {RNA815_22732}
9. MligTC455_20733 112 2.33 Mlig455_001969

Neo: Int S/G2/M

Age: -

Region-enriched R4: 5.601/0.00233

1.799 - - 0.824 - 0.975 - Mlig455_001969 {REF} {Length: 490} {NoTransDecoderORF} {RNA1310_88179}
10. MligTC455_17339 115 2.4 Mlig455_031354

Neo: -

Age: -

CHRNA2 1.797 - - 0.819 - 0.978 - Mlig455_031354 {REF} {Length: 2310} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=90.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=68.7]} {Human: ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=84.3, Expect=3e-17]; ENSG00000160716, CHRNB2, cholinergic receptor nicotinic beta 2 subunit, [Score=84.3, Expect=3e-17]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=83.6, Expect=5e-17]; ENSG00000169684, CHRNA5, cholinergic receptor nicotinic alpha 5 subunit, [Score=80.9, Expect=4e-16]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=80.1, Expect=9e-16]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=80.1, Expect=8e-16]} {Mouse: ENSMUSG00000027950, Chrnb2, cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal), [Score=85.1, Expect=2e-17]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=84.3, Expect=2e-17]; ENSMUSG00000035200, Chrnb4, cholinergic receptor, nicotinic, beta polypeptide 4, [Score=81.3, Expect=2e-16]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=76.3, Expect=1e-14]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=75.1, Expect=1e-14]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=81.6, Expect=7e-17]} {RNA1509_7752} {RNA1310_57458} {RNA815_42787}
11. MligTC455_16672 41 0.86 Mlig455_019194

Neo: -

Age: -

Region-enriched R2: 5.301/0.02053

1.793 - - 0.816 - 0.977 - Mlig455_019194 {REF} {Length: 648} {RNA1310_52751} {RNA815_26203}
12. MligTC455_17340 117 2.43 Mlig455_056518

Neo: -

Age: -

CHRNA3 1.792 - - 0.816 - 0.976 - Mlig455_056518 {REF} {Length: 2896} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=68.3]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=63.9, Expect=1e-11]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=59.7, Expect=2e-10]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=59.3, Expect=3e-10]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=57.0, Expect=2e-09]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=63.5, Expect=7e-12]} {Celegans: WBGene00001133, eat-2, Neuronal acetylcholine receptor subunit eat-2, [Score=56.2, Expect=2e-09]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=56.2, Expect=1e-09]} {RNA1509_7752} {RNA1310_57458} {RNA815_42787}
13. MligTC455_43116 105 2.2 Mlig455_006245, Mlig455_006299, Mlig455_061192

Neo: -

Age: -

ESRRB 1.775 - - 0.804 - 0.971 -

Mlig455_006245 {REF} {Length: 450} {NoTransDecoderORF}

Mlig455_006299 {REF} {Length: 2539} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.3]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=20.3]} {Human: ENSG00000119715, ESRRB, estrogen related receptor beta, [Score=94.4, Expect=2e-20]} {Mouse: ENSMUSG00000047638, Nr1h4, nuclear receptor subfamily 1, group H, member 4, [Score=88.2, Expect=1e-18]; ENSMUSG00000024955, Esrra, estrogen related receptor, alpha, [Score=86.7, Expect=3e-18]; ENSMUSG00000015846, Rxra, retinoid X receptor alpha, [Score=85.1, Expect=1e-17]; ENSMUSG00000023034, Nr4a1, nuclear receptor subfamily 4, group A, member 1, [Score=84.7, Expect=2e-17]} {Dmel: FBgn0035849, ERR, estrogen-related receptor, [Score=80.9, Expect=3e-16]} {Celegans: WBGene00003625, nhr-31, Nuclear hormone receptor family member nhr-31, [Score=84.3, Expect=2e-17]} {Smed: dd_Smed_v6_3012_0_1, dd_Smed_v6_3012_0_1, [Score=81.3, Expect=1e-16]} {RNA1310_86523}

Mlig455_061192 {REF} {Length: 2120} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.2]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=19.6]} {Human: ENSG00000119715, ESRRB, estrogen related receptor beta, [Score=97.4, Expect=2e-21]} {Mouse: ENSMUSG00000047638, Nr1h4, nuclear receptor subfamily 1, group H, member 4, [Score=94.4, Expect=1e-20]} {Dmel: FBgn0035849, ERR, estrogen-related receptor, [Score=80.1, Expect=4e-16]} {Celegans: WBGene00003625, nhr-31, Nuclear hormone receptor family member nhr-31, [Score=84.3, Expect=2e-17]} {Smed: dd_Smed_v6_13691_0_1, dd_Smed_v6_13691_0_1, [Score=79.7, Expect=1e-16]} {RNA1310_86523}
14. MligTC455_22916 416 8.67 Mlig455_002448, Mlig455_002725, Mlig455_063340

Neo: -

Age: -

CNOT6, CNOT6L 1.751 - - - 0.794 0.957 -

Mlig455_002448 {REF} {Length: 3594} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=28.2]} {Human: ENSG00000113300, CNOT6, CCR4-NOT transcription complex subunit 6, [Score=203, Expect=4e-58]; ENSG00000138767, CNOT6L, CCR4-NOT transcription complex subunit 6 like, [Score=200, Expect=6e-58]} {Mouse: ENSMUSG00000020362, Cnot6, CCR4-NOT transcription complex, subunit 6, [Score=199, Expect=6e-57]; ENSMUSG00000034724, Cnot6l, CCR4-NOT transcription complex, subunit 6-like, [Score=198, Expect=2e-57]} {Dmel: FBgn0011725, twin, [Score=214, Expect=2e-62]} {Celegans: WBGene00000376, ccr-4, CCR (Yeast CCR4/NOT complex component) homolog; CCR4, [Score=170, Expect=1e-47]} {Smed: dd_Smed_v6_5045_0_1, dd_Smed_v6_5045_0_1, [Score=162, Expect=1e-43]} {RNA1509_32917} {RNA1310_10507} {RNA815_11288}

Mlig455_002725 {REF} {Length: 3721} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=67.4]} {Human: ENSG00000138767, CNOT6L, CCR4-NOT transcription complex subunit 6 like, [Score=286, Expect=2e-88]; ENSG00000113300, CNOT6, CCR4-NOT transcription complex subunit 6, [Score=285, Expect=6e-88]} {Mouse: ENSMUSG00000034724, Cnot6l, CCR4-NOT transcription complex, subunit 6-like, [Score=285, Expect=4e-88]; ENSMUSG00000020362, Cnot6, CCR4-NOT transcription complex, subunit 6, [Score=283, Expect=1e-87]} {Dmel: FBgn0011725, twin, [Score=307, Expect=7e-97]} {Celegans: WBGene00000376, ccr-4, CCR (Yeast CCR4/NOT complex component) homolog; CCR4, [Score=250, Expect=4e-77]} {Smed: dd_Smed_v6_5045_0_1, dd_Smed_v6_5045_0_1, [Score=258, Expect=4e-78]} {RNA1509_32917} {RNA1310_10507} {RNA815_11288}

Mlig455_063340 {REF} {Length: 4128} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=67.6]} {Human: ENSG00000138767, CNOT6L, CCR4-NOT transcription complex subunit 6 like, [Score=285, Expect=6e-88]; ENSG00000113300, CNOT6, CCR4-NOT transcription complex subunit 6, [Score=284, Expect=1e-87]} {Mouse: ENSMUSG00000034724, Cnot6l, CCR4-NOT transcription complex, subunit 6-like, [Score=283, Expect=1e-87]; ENSMUSG00000020362, Cnot6, CCR4-NOT transcription complex, subunit 6, [Score=282, Expect=4e-87]} {Dmel: FBgn0011725, twin, [Score=307, Expect=5e-97]} {Celegans: WBGene00000376, ccr-4, CCR (Yeast CCR4/NOT complex component) homolog; CCR4, [Score=254, Expect=2e-78]} {Smed: dd_Smed_v6_5045_0_1, dd_Smed_v6_5045_0_1, [Score=256, Expect=4e-77]} {RNA1509_32917} {RNA1310_10507} {RNA815_11288}
15. MligTC455_36543 145 3.03 Mlig455_067860

Neo: -

Age: Down-Up-Up

MFSD8 1.749 - - - - 0.979 0.770 Mlig455_067860 {REF} {Length: 3751} {Pfam: Major Facilitator Superfamily [PF07690.18, score=87.6]} {Human: ENSG00000164073, MFSD8, major facilitator superfamily domain containing 8, [Score=61.2, Expect=2e-09]} {Mouse: ENSMUSG00000116169, Mfsd8, major facilitator superfamily domain containing 8, [Score=58.2, Expect=2e-09]; ENSMUSG00000025759, Mfsd8, major facilitator superfamily domain containing 8, [Score=58.2, Expect=2e-09]} {Smed: dd_Smed_v6_9883_0_1, dd_Smed_v6_9883_0_1, [RH, Score=369, Expect=7e-123]} {RNA1509_54938} {RNA1310_19930} {RNA815_20915}
16. MligTC455_45817 492 10.24 Mlig455_004593, Mlig455_064772

Neo: -

Age: -

RRAD 1.745 - - - 0.791 0.954 -

Mlig455_004593 {REF} {Length: 2289} {Pfam: Ras family [PF00071.24, score=69.4]; RsgA GTPase [PF03193.18, score=22.0]; ADP-ribosylation factor family [PF00025.23, score=20.1]} {Human: ENSG00000166592, RRAD, RRAD, Ras related glycolysis inhibitor and calcium channel regulator, [Score=81.3, Expect=6e-18]; ENSG00000164949, GEM, GTP binding protein overexpressed in skeletal muscle, [Score=78.6, Expect=4e-17]; ENSG00000139890, REM2, RRAD and GEM like GTPase 2, [Score=78.2, Expect=8e-17]} {Mouse: ENSMUSG00000031880, Rrad, Ras-related associated with diabetes, [Score=80.5, Expect=8e-18]; ENSMUSG00000028214, Gem, GTP binding protein (gene overexpressed in skeletal muscle), [Score=77.8, Expect=7e-17]; ENSMUSG00000022176, Rem2, rad and gem related GTP binding protein 2, [Score=77.8, Expect=8e-17]} {Dmel: FBgn0264753, Rgk1, Rad, Gem/Kir family member 1, [Score=107, Expect=3e-27]} {Celegans: WBGene00013124, Y52B11A.4, [Score=60.1, Expect=9e-11]} {Smed: dd_Smed_v6_11010_0_1, dd_Smed_v6_11010_0_1, [Score=130, Expect=3e-36]} {RNA1509_20692} {RNA1310_28257.1} {RNA815_21843}

Mlig455_064772 {REF} {Length: 4499} {Pfam: Ras family [PF00071.24, score=78.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=27.1]; ADP-ribosylation factor family [PF00025.23, score=23.3]; RsgA GTPase [PF03193.18, score=21.6]} {Human: ENSG00000166592, RRAD, RRAD, Ras related glycolysis inhibitor and calcium channel regulator, [Score=91.3, Expect=1e-19]; ENSG00000164949, GEM, GTP binding protein overexpressed in skeletal muscle, [Score=88.6, Expect=8e-19]} {Mouse: ENSMUSG00000031880, Rrad, Ras-related associated with diabetes, [Score=93.2, Expect=2e-20]} {Dmel: FBgn0264753, Rgk1, Rad, Gem/Kir family member 1, [RH, Score=137, Expect=8e-34]} {Celegans: WBGene00010038, rheb-1, GTP-binding protein Rheb homolog 1, [Score=73.9, Expect=6e-15]} {Smed: dd_Smed_v6_11010_0_1, dd_Smed_v6_11010_0_1, [RH, Score=170, Expect=2e-47]} {RNA1509_15087, RNA1509_20692, RNA1509_37785} {RNA1310_15968.2, RNA1509_15087, RNA1509_20692} {RNA1509_15087, RNA1509_20692, RNA815_18047}
17. MligTC455_20957 40 0.84 Mlig455_009152

Neo: -

Age: -

1.742 - - 0.763 - 0.979 - Mlig455_009152 {REF} {Length: 1951} {RNA1310_39190} {RNA815_29274}
18. MligTC455_29571 479 9.99 Mlig455_040381

Neo: -

Age: -

Region-enriched R4: 1.349/0.03232

TRAF3 1.728 - - 0.752 - 0.976 - Mlig455_040381 {REF} {Length: 4738} {TRANSSPLICED} {Pfam: TRAF-type zinc finger [PF02176.20, score=31.1]; zinc finger of C3HC4-type, RING [PF15227.8, score=21.9]; zf-RING of BARD1-type protein [PF14835.8, score=19.2]} {Human: ENSG00000131323, TRAF3, TNF receptor associated factor 3, [RH, Score=300, Expect=2e-94]} {Mouse: ENSMUSG00000021277, Traf3, TNF receptor-associated factor 3, [RH, Score=298, Expect=6e-94]; ENSMUSG00000111385, Traf5, TNF receptor-associated factor 5, [RH, Score=292, Expect=1e-91]; ENSMUSG00000026637, Traf5, TNF receptor-associated factor 5, [RH, Score=292, Expect=1e-91]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=122, Expect=1e-29]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [Score=101, Expect=7e-23]} {Smed: dd_Smed_v6_4148_0_1, dd_Smed_v6_4148_0_1, [RH, Score=194, Expect=4e-56]} {RNA1509_2193, RNA1509_24774, RNA1509_35341, RNA1509_54605} {RNA1310_5587.1, RNA1509_24774, RNA1509_35341, RNA1509_54605} {RNA1509_24774, RNA1509_35341, RNA1509_54605, RNA815_4083.2}
19. MligTC455_48545 413 8.6 Mlig455_007143

Neo: -

Age: Up-Down-Down

EDEM3 1.726 - - - 0.752 0.974 - Mlig455_007143 {REF} {Length: 5756} {TRANSSPLICED} {Pfam: Glycosyl hydrolase family 47 [PF01532.22, score=392.3]; PA domain [PF02225.24, score=29.8]} {Human: ENSG00000116406, EDEM3, ER degradation enhancing alpha-mannosidase like protein 3, [RH, Score=677, Expect=0.0]} {Mouse: ENSMUSG00000043019, Edem3, ER degradation enhancer, mannosidase alpha-like 3, [RH, Score=681, Expect=0.0]} {Dmel: FBgn0032480, Edem2, ER degradation enhancer, mannosidase alpha-like 2, [RH, Score=711, Expect=0.0]} {Celegans: WBGene00013919, ZC506.1, alpha-1,2-Mannosidase, [RH, Score=649, Expect=0.0]} {Smed: dd_Smed_v6_13088_0_1, dd_Smed_v6_13088_0_1, [RH, Score=396, Expect=3e-130]} {RNA1509_12238} {RNA1310_4248} {RNA815_2991}
20. MligTC455_30613 560 11.68 Mlig455_066031

Neo: -

Age: Up-Down-Down

HCK 1.725 - - - - 0.989 0.736 Mlig455_066031 {REF} {Length: 4573} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=313.0]; Protein kinase domain [PF00069.27, score=164.9]; SH2 domain [PF00017.26, score=61.3]; SH3 domain [PF00018.30, score=49.4]; Variant SH3 domain [PF14604.8, score=42.0]; Variant SH3 domain [PF07653.19, score=32.2]; ABC1 atypical kinase-like domain [PF03109.18, score=23.5]; Haspin like kinase domain [PF12330.10, score=18.6]} {Human: ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [RH, Score=443, Expect=5e-151]} {Mouse: ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [RH, Score=443, Expect=7e-151]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=447, Expect=1e-152]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=418, Expect=7e-142]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [RH, Score=599, Expect=0.0]} {RNA1509_17483, RNA1509_47972} {RNA1310_7339, RNA1509_17483, RNA1509_47972} {RNA1509_17483, RNA1509_47972, RNA815_2133.1}
21. MligTC455_34424 211 4.39 Mlig455_053796

Neo: -

Age: Down-Up-Down

CUTA 1.722 0.746 - - - 0.976 - Mlig455_053796 {REF} {Length: 1849} {TRANSSPLICED} {Pfam: CutA1 divalent ion tolerance protein [PF03091.17, score=117.6]} {Human: ENSG00000112514, CUTA, cutA divalent cation tolerance homolog, [Score=106, Expect=4e-29]; ENSG00000226492, CUTA, cutA divalent cation tolerance homolog, [Score=106, Expect=4e-29]} {Mouse: ENSMUSG00000024194, Cuta, cutA divalent cation tolerance homolog, [Score=107, Expect=5e-30]} {Dmel: FBgn0030545, CG11590, [Score=104, Expect=1e-28]} {Celegans: WBGene00009443, F35G12.7, [Score=69.7, Expect=4e-16]} {Smed: dd_Smed_v6_6861_0_1, dd_Smed_v6_6861_0_1, [RH, Score=102, Expect=1e-28]} {RNA1509_15594, RNA1509_53817, RNA1509_58708} {RNA1310_36008, RNA1509_15594, RNA1509_53817, RNA1509_58708} {RNA1509_15594, RNA1509_53817, RNA1509_58708, RNA815_21743.1}
22. MligTC455_39952 315 6.57 Mlig455_040218

Neo: -

Age: -

1.718 - - - 0.754 0.964 - Mlig455_040218 {REF} {Length: 1140} {NoTransDecoderORF} {RNA1509_46890} {RNA1310_43516} {RNA815_33155}
23. MligTC455_15887 275 5.74 Mlig455_014231, Mlig455_044928

Neo: Irradiation

Age: -

1.717 0.759 - - - 0.958 -

Mlig455_014231 {REF} {Length: 3468} {TRANSSPLICED} {RNA1509_39956, RNA1509_46366} {RNA1310_5128.1, RNA1509_46366} {RNA1509_46366, RNA815_18027}

Mlig455_044928 {REF} {Length: 3268} {TRANSSPLICED} {RNA1509_39956} {RNA1310_5128.1} {RNA815_26969}
24. MligTC455_33064 105 2.19 Mlig455_011926

Neo: -

Age: -

1.715 - - - - 0.970 0.745 Mlig455_011926 {REF} {Length: 2070} {NoTransDecoderORF} {RNA1509_28565} {RNA1310_15235.1} {RNA815_20023}
25. MligTC455_19945 635 13.23 Mlig455_004844

Neo: Int S/G2/M

Age: Down-Up-Up

Region-enriched R5: 1.886/0.00002
Region-enriched R4: 1.500/0.02485

SLC30A7 1.714 0.745 - - - 0.969 - Mlig455_004844 {REF} {Length: 543} {TRANSSPLICED} {Pfam: Cation efflux family [PF01545.23, score=168.4]; Rpp14/Pop5 family [PF01900.21, score=71.5]} {Human: ENSG00000162695, SLC30A7, solute carrier family 30 member 7, [Score=431, Expect=1e-148]} {Mouse: ENSMUSG00000054414, Slc30a7, solute carrier family 30 (zinc transporter), member 7, [Score=416, Expect=8e-143]} {Dmel: FBgn0037875, ZnT86D, Zinc transporter 86D, [RH, Score=384, Expect=2e-130]} {Celegans: WBGene00000393, cdf-1, Cation diffusion facilitator family protein 1, [Score=102, Expect=6e-23]} {Smed: dd_Smed_v6_4378_0_1, dd_Smed_v6_4378_0_1, [Score=243, Expect=7e-72]} {RNA1509_34159, RNA1509_39378} {RNA1310_60743, RNA1509_34159, RNA1509_39378} {RNA1509_34159, RNA1509_39378, RNA815_30594}
26. MligTC455_25797 106 2.22 Mlig455_020828

Neo: -

Age: Down-Up-Down

1.712 - - 0.739 - 0.973 - Mlig455_020828 {REF} {Length: 3021} {Smed: dd_Smed_v6_91651_0_1, dd_Smed_v6_91651_0_1, [Score=49.7, Expect=4e-08]} {RNA1509_46103} {RNA1310_6410.1} {RNA815_31889}
27. MligTC455_19355 1316 27.42 Mlig455_028094, Mlig455_045219

Neo: -

Age: -

EEPD1 1.71 - - - - 0.957 0.753

Mlig455_028094 {REF} {Length: 4146} {TRANSSPLICED} {Pfam: Helix-hairpin-helix motif [PF12836.9, score=91.0]; Helix-hairpin-helix motif [PF00633.25, score=45.7]; Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=27.7]; Helix-hairpin-helix domain [PF14520.8, score=23.8]; Type II secretion system (T2SS), protein K [PF03934.15, score=21.9]; Helix-hairpin-helix motif [PF14579.8, score=20.4]; Transposase IS116/IS110/IS902 family [PF02371.18, score=19.1]} {Human: ENSG00000122547, EEPD1, endonuclease/exonuclease/phosphatase family domain containing 1, [RH, Score=338, Expect=4e-108]} {Mouse: ENSMUSG00000036611, Eepd1, endonuclease/exonuclease/phosphatase family domain containing 1, [RH, Score=327, Expect=4e-104]} {Smed: dd_Smed_v6_15723_0_1, dd_Smed_v6_15723_0_1, [RH, Score=214, Expect=9e-64]} {RNA1509_19761, RNA1509_28792, RNA1509_54509, RNA1509_7474} {RNA1310_12271.1, RNA1509_19761, RNA1509_28792, RNA1509_54509} {RNA1509_19761, RNA1509_28792, RNA1509_54509, RNA815_19714}

Mlig455_045219 {REF} {Length: 3893} {TRANSSPLICED} {Pfam: Helix-hairpin-helix motif [PF12836.9, score=91.0]; Helix-hairpin-helix motif [PF00633.25, score=45.7]; Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=26.6]; Helix-hairpin-helix domain [PF14520.8, score=23.9]; Type II secretion system (T2SS), protein K [PF03934.15, score=21.9]; Helix-hairpin-helix motif [PF14579.8, score=20.4]; Transposase IS116/IS110/IS902 family [PF02371.18, score=19.2]} {Human: ENSG00000122547, EEPD1, endonuclease/exonuclease/phosphatase family domain containing 1, [RH, Score=338, Expect=4e-108]} {Mouse: ENSMUSG00000036611, Eepd1, endonuclease/exonuclease/phosphatase family domain containing 1, [RH, Score=327, Expect=5e-104]} {Smed: dd_Smed_v6_15723_0_1, dd_Smed_v6_15723_0_1, [RH, Score=213, Expect=3e-63]} {RNA1509_7474} {RNA1310_12271.1, RNA1509_7474} {RNA1509_7474, RNA815_19714}
28. MligTC455_20005 66 1.37 Mlig455_058873

Neo: -

Age: -

1.708 - - - 0.726 0.982 - Mlig455_058873 {REF} {Length: 1698} {NoTransDecoderORF} {RNA1509_49659} {RNA1310_35915} {RNA815_53530}
29. MligTC455_54150 45 0.93 Mlig455_040594

Neo: -

Age: -

1.708 - - 0.731 - 0.977 - Mlig455_040594 {REF} {Length: 2865} {TRANSSPLICED} {RNA1310_34799.1} {RNA815_13806}
30. MligTC455_38536 1494 31.12 Mlig455_068146

Neo: -

Age: logFC(26M/2M)=-0.338

PSMB7 1.704 - - - - 0.967 0.737 Mlig455_068146 {REF} {Length: 1648} {TRANSSPLICED} {Pfam: Proteasome subunit [PF00227.28, score=169.0]} {Human: ENSG00000136930, PSMB7, proteasome subunit beta 7, [RH, Score=319, Expect=2e-109]} {Mouse: ENSMUSG00000026750, Psmb7, proteasome (prosome, macropain) subunit, beta type 7, [RH, Score=319, Expect=1e-109]} {Dmel: FBgn0023174, Prosbeta2, Proteasome beta2 subunit, [RH, Score=287, Expect=4e-97]} {Celegans: WBGene00003948, pbs-2, Proteasome subunit beta type, [RH, Score=198, Expect=4e-62]} {Smed: dd_Smed_v6_1264_0_1, dd_Smed_v6_1264_0_1, [RH, Score=298, Expect=1e-101]} {RNA1509_11730} {RNA1310_16755.1} {RNA815_14858}
31. MligTC455_38720 72 1.5 Mlig455_065562

Neo: -

Age: Up-Down-Down

COL4A6 1.703 - - - 0.737 0.966 - Mlig455_065562 {REF} {Length: 6263} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=613.8]; C-terminal tandem repeated domain in type 4 procollagen [PF01413.21, score=202.1]} {Human: ENSG00000197565, COL4A6, collagen type IV alpha 6 chain, [Score=502, Expect=6e-149]} {Mouse: ENSMUSG00000031273, Col4a6, collagen, type IV, alpha 6, [Score=514, Expect=3e-153]; ENSMUSG00000116510, Col4a6, collagen, type IV, alpha 6, [Score=514, Expect=3e-153]} {Dmel: FBgn0016075, vkg, viking, [Score=596, Expect=0.0]} {Celegans: WBGene00001263, emb-9, Collagen alpha-1(IV) chain, [Score=583, Expect=1e-177]} {Smed: dd_Smed_v6_2337_0_1, dd_Smed_v6_2337_0_1, [Score=738, Expect=0.0]} {RNA1509_23572, RNA1509_35895, RNA1509_45361, RNA1509_5346} {RNA1310_692.1, RNA1509_23572, RNA1509_35895, RNA1509_45361} {RNA1509_23572, RNA1509_35895, RNA1509_45361, RNA815_573}
32. MligTC455_23301 649 13.52 Mlig455_001085, Mlig455_001094

Neo: -

Age: -

Region-enriched R4: 2.339/0.01585

JMY 1.7 - - - - 0.954 0.746

Mlig455_001085 {REF} {Length: 3815} {TRANSSPLICED} {Pfam: Junction-mediating and -regulatory protein [PF15871.7, score=167.4]; N-terminal of Junction-mediating and WASP homolog-associated [PF15920.7, score=22.2]} {Human: ENSG00000152409, JMY, junction mediating and regulatory protein, p53 cofactor, [Score=98.2, Expect=2e-20]} {Mouse: ENSMUSG00000021690, Jmy, junction-mediating and regulatory protein, [Score=107, Expect=2e-23]} {Smed: dd_Smed_v6_8514_0_5, dd_Smed_v6_8514_0_5, [Score=60.8, Expect=2e-09]} {RNA1509_26050, RNA1509_33438} {RNA1310_12940.2, RNA1509_33438} {RNA1509_33438, RNA815_6948}

Mlig455_001094 {REF} {Length: 3742} {TRANSSPLICED} {Pfam: Junction-mediating and -regulatory protein [PF15871.7, score=167.3]; N-terminal of Junction-mediating and WASP homolog-associated [PF15920.7, score=22.3]} {Human: ENSG00000152409, JMY, junction mediating and regulatory protein, p53 cofactor, [Score=70.5, Expect=7e-12]} {Mouse: ENSMUSG00000021690, Jmy, junction-mediating and regulatory protein, [Score=92.8, Expect=5e-19]} {Smed: dd_Smed_v6_8514_0_4, dd_Smed_v6_8514_0_4, [Score=53.1, Expect=4e-07]} {RNA1509_26050} {RNA1310_12940.1} {RNA815_6948}
33. MligTC455_48098 257 5.35 Mlig455_021058

Neo: -

Age: -

ING4 1.699 - - - - 0.960 0.739 Mlig455_021058 {REF} {Length: 3102} {TRANSSPLICED} {Pfam: Inhibitor of growth proteins N-terminal histone-binding [PF12998.9, score=97.0]; Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) [PF08285.13, score=32.9]; PHD-finger [PF00628.31, score=27.0]} {Human: ENSG00000111653, ING4, inhibitor of growth family member 4, [RH, Score=253, Expect=2e-82]; ENSG00000168395, ING5, inhibitor of growth family member 5, [RH, Score=243, Expect=8e-79]} {Mouse: ENSMUSG00000026283, Ing5, inhibitor of growth family, member 5, [RH, Score=258, Expect=2e-84]; ENSMUSG00000030330, Ing4, inhibitor of growth family, member 4, [RH, Score=251, Expect=1e-81]} {Dmel: FBgn0032516, Ing5, Inhibitor of growth family member 5, [RH, Score=235, Expect=2e-75]} {Celegans: WBGene00013095, ing-3, Inhibitor of growth protein, [RH, Score=78.2, Expect=1e-15]} {Smed: dd_Smed_v6_7721_0_1, dd_Smed_v6_7721_0_1, [Score=203, Expect=3e-63]} {RNA1509_42044} {RNA1310_33909} {RNA815_37273}
34. MligTC455_27333 197 4.09 Mlig455_034505, Mlig455_066273

Neo: -

Age: Up-Down-Up

ADK 1.698 - - - 0.728 0.970 -

Mlig455_034505 {REF} {Length: 2251} {Pfam: pfkB family carbohydrate kinase [PF00294.26, score=133.8]} {Human: ENSG00000156110, ADK, adenosine kinase, [Score=189, Expect=3e-56]} {Mouse: ENSMUSG00000039197, Adk, adenosine kinase, [Score=196, Expect=7e-59]} {Dmel: FBgn0037995, CG3809, [Score=171, Expect=4e-49]} {Celegans: WBGene00011128, R07H5.8, [Score=192, Expect=8e-58]} {Smed: dd_Smed_v6_627_0_1, dd_Smed_v6_627_0_1, [Score=193, Expect=2e-58]} {RNA1310_14200} {RNA815_18352}

Mlig455_066273 {REF} {Length: 3009} {TRANSSPLICED} {Pfam: pfkB family carbohydrate kinase [PF00294.26, score=64.6]} {Human: ENSG00000156110, ADK, adenosine kinase, [Score=61.2, Expect=1e-11]} {Mouse: ENSMUSG00000039197, Adk, adenosine kinase, [Score=65.1, Expect=4e-13]} {Dmel: FBgn0037995, CG3809, [Score=61.6, Expect=5e-12]} {Celegans: WBGene00011128, R07H5.8, [Score=62.8, Expect=1e-12]} {Smed: dd_Smed_v6_627_0_1, dd_Smed_v6_627_0_1, [Score=61.6, Expect=3e-12]} {RNA1310_14200} {RNA815_23177}
35. MligTC455_41857 148 3.08 Mlig455_037828

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.788

BRD8 1.698 - - 0.730 - 0.968 - Mlig455_037828 {REF} {Length: 2010} {TRANSSPLICED} {Pfam: Bromodomain [PF00439.27, score=33.1]} {Human: ENSG00000112983, BRD8, bromodomain containing 8, [Score=69.3, Expect=9e-12]} {Mouse: ENSMUSG00000003778, Brd8, bromodomain containing 8, [Score=69.3, Expect=7e-12]} {Dmel: FBgn0050417, tbrd-3, testis-specifically expressed bromodomain containing protein-3, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_10362_1_1, dd_Smed_v6_10362_1_1, [RH, Score=57.0, Expect=1e-08]} {RNA1509_27181} {RNA1310_17527} {RNA815_26572}
36. MligTC455_51800 518 10.79 Mlig455_041708

Neo: -

Age: Up-Down-Down

YME1L1 1.698 - - - - 0.950 0.748 Mlig455_041708 {REF} {Length: 5534} {TRANSSPLICED} {Pfam: Peptidase family M41 [PF01434.20, score=176.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=143.1]; AAA+ lid domain [PF17862.3, score=25.9]; AAA ATPase domain [PF13191.8, score=24.7]; AAA domain [PF13401.8, score=22.7]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=21.7]; AAA domain (dynein-related subfamily) [PF07728.16, score=21.7]; TIP49 P-loop domain [PF06068.15, score=17.9]} {Human: ENSG00000136758, YME1L1, YME1 like 1 ATPase, [RH, Score=462, Expect=2e-152]} {Mouse: ENSMUSG00000026775, Yme1l1, YME1-like 1 (S. cerevisiae), [RH, Score=460, Expect=2e-151]} {Dmel: FBgn0034792, YME1L, YME1 like ATPase, [RH, Score=484, Expect=2e-160]} {Celegans: WBGene00010842, ymel-1, ATP-dependent zinc metalloprotease YME1 homolog, [RH, Score=471, Expect=9e-156]} {Smed: dd_Smed_v6_962_0_1, dd_Smed_v6_962_0_1, [RH, Score=446, Expect=9e-147]} {RNA1509_45054, RNA1509_7847} {RNA1310_2453.1, RNA1509_45054, RNA1509_7847} {RNA1509_45054, RNA1509_7847, RNA815_3285}
37. MligTC455_53458 490 10.2 Mlig455_043903

Neo: -

Age: -

Region-enriched R4: 1.660/0.01970

CENPV 1.693 - - 0.717 - 0.976 - Mlig455_043903 {REF} {Length: 728} {TRANSSPLICED} {Pfam: Glutathione-dependent formaldehyde-activating enzyme [PF04828.16, score=28.4]} {Human: ENSG00000166582, CENPV, centromere protein V, [RH, Score=166, Expect=5e-52]} {Mouse: ENSMUSG00000018509, Cenpv, centromere protein V, [RH, Score=166, Expect=3e-52]} {Celegans: WBGene00017771, F25B4.8, [RH, Score=133, Expect=5e-41]} {RNA1509_40162, RNA1509_54657} {RNA1310_54553, RNA1509_40162, RNA1509_54657} {RNA1509_40162, RNA1509_54657, RNA815_40144}
38. MligTC455_24400 237 4.93 Mlig455_007323, Mlig455_068326

Neo: -

Age: -

KCNAB2 1.692 - 0.710 - - 0.982 -

Mlig455_007323 {REF} {Length: 3488} {Pfam: Aldo/keto reductase family [PF00248.23, score=187.7]} {Human: ENSG00000069424, KCNAB2, potassium voltage-gated channel subfamily A regulatory beta subunit 2, [RH, Score=502, Expect=1e-175]; ENSG00000169282, KCNAB1, potassium voltage-gated channel subfamily A member regulatory beta subunit 1, [RH, Score=481, Expect=2e-166]} {Mouse: ENSMUSG00000028931, Kcnab2, potassium voltage-gated channel, shaker-related subfamily, beta member 2, [RH, Score=505, Expect=8e-177]; ENSMUSG00000027827, Kcnab1, potassium voltage-gated channel, shaker-related subfamily, beta member 1, [RH, Score=481, Expect=1e-166]} {Dmel: FBgn0263220, Hk, Hyperkinetic, [RH, Score=322, Expect=3e-99]} {Celegans: WBGene00015565, C07D8.6, [Score=58.9, Expect=3e-09]} {RNA1509_10965} {RNA1310_75287} {RNA815_44952}

Mlig455_068326 {REF} {Length: 3179} {Pfam: Aldo/keto reductase family [PF00248.23, score=181.5]} {Human: ENSG00000069424, KCNAB2, potassium voltage-gated channel subfamily A regulatory beta subunit 2, [RH, Score=453, Expect=2e-161]} {Mouse: ENSMUSG00000028931, Kcnab2, potassium voltage-gated channel, shaker-related subfamily, beta member 2, [Score=458, Expect=7e-163]} {Dmel: FBgn0263220, Hk, Hyperkinetic, [Score=294, Expect=1e-97]} {Celegans: WBGene00015565, C07D8.6, [Score=49.7, Expect=1e-06]} {RNA1509_10965} {RNA1310_87215.1} {RNA815_44952}
39. MligTC455_00898 410 8.55 Mlig455_046231, Mlig455_068972

Neo: -

Age: -

1.69 - - 0.734 - 0.956 -

Mlig455_046231 {REF} {Length: 2553} {RNA1509_60110} {RNA1310_41937, RNA1509_60110}

Mlig455_068972 {REF} {Length: 4025} {RNA1509_17147} {RNA1310_59800, RNA1509_17147} {RNA1509_17147, RNA815_35589}
40. MligTC455_17842 957 19.93 Mlig455_070916

Neo: -

Age: -

NARS 1.686 0.701 - - - 0.985 - Mlig455_070916 {REF} {Length: 2687} {TRANSSPLICED} {Pfam: tRNA synthetases class II (D, K and N) [PF00152.22, score=332.3]; OB-fold nucleic acid binding domain [PF01336.27, score=43.3]} {Human: ENSG00000134440, NARS, asparaginyl-tRNA synthetase, [RH, Score=737, Expect=0.0]} {Mouse: ENSMUSG00000024587, Nars, asparaginyl-tRNA synthetase, [RH, Score=723, Expect=0.0]} {Dmel: FBgn0086443, AsnRS, Asparaginyl-tRNA synthetase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00003815, nars-1, Asparagine--tRNA ligase, cytoplasmic, [RH, Score=623, Expect=0.0]} {Smed: dd_Smed_v6_2691_0_1, dd_Smed_v6_2691_0_1, [RH, Score=587, Expect=0.0]} {RNA1509_5093} {RNA1310_14490, RNA1509_5093} {RNA1509_5093, RNA815_5353}
41. MligTC455_15163 82 1.71 Mlig455_013866

Neo: -

Age: -

1.685 - - 0.712 - 0.973 - Mlig455_013866 {REF} {Length: 1650} {Pfam: Glycine rich protein [PF12810.9, score=27.4]} {RNA1310_45253} {RNA815_29629}
42. MligTC455_49850 509 10.6 Mlig455_035477

Neo: -

Age: Down-Up-Down

Region-enriched R5: 1.344/0.00228

NADK2 1.682 0.723 - - - 0.959 - Mlig455_035477 {REF} {Length: 2586} {Pfam: ATP-NAD kinase N-terminal domain [PF01513.23, score=27.0]} {Human: ENSG00000152620, NADK2, NAD kinase 2, mitochondrial, [Score=248, Expect=4e-77]} {Mouse: ENSMUSG00000022253, Nadk2, NAD kinase 2, mitochondrial, [Score=249, Expect=3e-78]; ENSMUSG00000111527, Nadk2, NAD kinase 2, mitochondrial, [Score=237, Expect=3e-73]} {Dmel: FBgn0033373, CG8080, [Score=200, Expect=1e-59]} {Celegans: WBGene00012463, Y17G7B.10, NAD kinase 2, mitochondrial, [Score=298, Expect=3e-97]} {Smed: dd_Smed_v6_8674_0_1, dd_Smed_v6_8674_0_1, [Score=296, Expect=8e-97]} {RNA1509_15824} {RNA1310_6455.1} {RNA815_24091}
43. MligTC455_39462 179 3.73 Mlig455_025851

Neo: -

Age: -

1.679 - - 0.708 - 0.971 - Mlig455_025851 {REF} {Length: 2579} {Pfam: Lectin C-type domain [PF00059.23, score=35.0]} {Smed: dd_Smed_v6_84586_0_1, dd_Smed_v6_84586_0_1, [RH, Score=53.1, Expect=4e-09]} {RNA1509_47157} {RNA1310_37139.1} {RNA815_40603}
44. MligTC455_42455 161 3.35 Mlig455_005868, Mlig455_018891

Neo: -

Age: Up-Down-Up

NYNRIN 1.675 - - - 0.718 0.957 -

Mlig455_005868 {REF} {Length: 4106} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=102.4]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=94.8]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=70.0]; Integrase zinc binding domain [PF17921.3, score=52.8]; Integrase core domain [PF00665.28, score=45.4]; gag-polyprotein putative aspartyl protease [PF13975.8, score=34.5]; Aspartyl protease [PF13650.8, score=21.5]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=72.0, Expect=8e-12]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=68.9, Expect=4e-11]; ENSMUSG00000085925, Rtl1, retrotransposon Gaglike 1, [Score=68.6, Expect=5e-11]; ENSMUSG00000098639, Rtl1, retrotransposon Gaglike 1, [Score=68.6, Expect=5e-11]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=262, Expect=1e-72]} {RNA1509_29592} {RNA1310_10223} {RNA815_18935}

Mlig455_018891 {REF} {Length: 793} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=102.4]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=94.8]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=70.0]; Integrase zinc binding domain [PF17921.3, score=52.8]; Integrase core domain [PF00665.28, score=45.4]; gag-polyprotein putative aspartyl protease [PF13975.8, score=34.5]; Aspartyl protease [PF13650.8, score=21.5]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=72.0, Expect=8e-12]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=68.9, Expect=4e-11]; ENSMUSG00000085925, Rtl1, retrotransposon Gaglike 1, [Score=68.6, Expect=5e-11]; ENSMUSG00000098639, Rtl1, retrotransposon Gaglike 1, [Score=68.6, Expect=5e-11]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=262, Expect=1e-72]} {RNA1509_29592} {RNA1310_10223} {RNA815_25405.1}
45. MligTC455_43813 94 1.96 Mlig455_061375

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=1.512

1.674 - - - - 0.955 0.719 Mlig455_061375 {REF} {Length: 1683} {TRANSSPLICED} {RNA1509_17916} {RNA1310_11712} {RNA815_9244}
46. MligTC455_15354 91 1.89 Mlig455_032589

Neo: -

Age: -

FURIN 1.673 - - - - 0.965 0.708 Mlig455_032589 {REF} {Length: 3369} {Pfam: Subtilase family [PF00082.24, score=155.9]; Proprotein convertase P-domain [PF01483.22, score=73.0]; Peptidase S8 pro-domain [PF16470.7, score=71.0]} {Human: ENSG00000140564, FURIN, furin, paired basic amino acid cleaving enzyme, [RH, Score=551, Expect=0.0]; ENSG00000140479, PCSK6, proprotein convertase subtilisin/kexin type 6, [RH, Score=545, Expect=0.0]} {Mouse: ENSMUSG00000030530, Furin, furin (paired basic amino acid cleaving enzyme), [RH, Score=551, Expect=0.0]; ENSMUSG00000030513, Pcsk6, proprotein convertase subtilisin/kexin type 6, [RH, Score=541, Expect=1e-180]; ENSMUSG00000024713, Pcsk5, proprotein convertase subtilisin/kexin type 5, [RH, Score=528, Expect=1e-175]} {Dmel: FBgn0004509, Fur1, Furin 1, [RH, Score=558, Expect=0.0]} {Celegans: WBGene00002232, kpc-1, Furin-like protease kpc-1, [RH, Score=558, Expect=0.0]} {Smed: dd_Smed_v6_10832_0_1, dd_Smed_v6_10832_0_1, [RH, Score=622, Expect=0.0]} {RNA1509_27501} {RNA1310_7852} {RNA815_2403.1}
47. MligTC455_52066 838 17.45 Mlig455_024600

Neo: Int S/G2/M

Age: -

Region-enriched R4: 1.542/0.00420

RTN4 1.662 0.707 - - - 0.955 - Mlig455_024600 {REF} {Length: 2031} {TRANSSPLICED} {Pfam: Reticulon [PF02453.19, score=87.5]} {Human: ENSG00000115310, RTN4, reticulon 4, [RH, Score=87.4, Expect=9e-19]} {Mouse: ENSMUSG00000020458, Rtn4, reticulon 4, [RH, Score=88.2, Expect=8e-21]} {Dmel: FBgn0053113, Rtnl1, Reticulon-like1, [RH, Score=103, Expect=1e-24]} {Smed: dd_Smed_v6_4451_0_1, dd_Smed_v6_4451_0_1, [RH, Score=58.2, Expect=3e-10]} {RNA1509_25959, RNA1509_31648, RNA1509_48670} {RNA1310_34226, RNA1509_25959, RNA1509_31648, RNA1509_48670} {RNA1509_25959, RNA1509_31648, RNA1509_48670, RNA815_15914}
48. MligTC455_25721 60 1.26 Mlig455_004763

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.345

SLC43A3 1.661 - - - 0.711 0.950 - Mlig455_004763 {REF} {Length: 2625} {TRANSSPLICED} {Pfam: Sugar (and other) transporter [PF00083.26, score=18.6]} {Human: ENSG00000134802, SLC43A3, solute carrier family 43 member 3, [Score=71.6, Expect=1e-12]} {Smed: dd_Smed_v6_28076_0_1, dd_Smed_v6_28076_0_1, [Score=53.1, Expect=2e-07]} {RNA1509_12947} {RNA1310_7286.2} {RNA815_11365}
49. MligTC455_51217 444 9.25 Mlig455_041300, Mlig455_056202

Neo: -

Age: Up-Down-Down

ESRP1 1.656 - - 0.705 - 0.951 -

Mlig455_041300 {REF} {Length: 5896} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=26.0]} {Human: ENSG00000104413, ESRP1, epithelial splicing regulatory protein 1, [Score=328, Expect=1e-101]} {Mouse: ENSMUSG00000040728, Esrp1, epithelial splicing regulatory protein 1, [Score=325, Expect=1e-100]} {Dmel: FBgn0023441, fus, fusilli, [Score=342, Expect=2e-105]} {Celegans: WBGene00006367, sym-2, RNA-binding protein sym-2, [Score=224, Expect=9e-64]} {Smed: dd_Smed_v6_5053_0_1, dd_Smed_v6_5053_0_1, [Score=365, Expect=8e-115]} {RNA1509_30547} {RNA1310_6783.1} {RNA815_42738.2}

Mlig455_056202 {REF} {Length: 4730} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=25.9]} {Human: ENSG00000104413, ESRP1, epithelial splicing regulatory protein 1, [Score=327, Expect=5e-101]} {Mouse: ENSMUSG00000040728, Esrp1, epithelial splicing regulatory protein 1, [Score=325, Expect=2e-100]} {Dmel: FBgn0023441, fus, fusilli, [Score=342, Expect=2e-105]} {Celegans: WBGene00006367, sym-2, RNA-binding protein sym-2, [Score=223, Expect=2e-63]} {Smed: dd_Smed_v6_5053_0_1, dd_Smed_v6_5053_0_1, [Score=365, Expect=1e-114]} {RNA1509_30547} {RNA1310_6783.1} {RNA815_42738.2}
50. MligTC455_44764 855 17.82 Mlig455_001799, Mlig455_001814

Neo: -

Age: -

ZDHHC14 1.655 - - - - 0.953 0.702

Mlig455_001799 {REF} {Length: 2650} {TRANSSPLICED} {Pfam: DHHC palmitoyltransferase [PF01529.22, score=128.6]} {Human: ENSG00000175048, ZDHHC14, zinc finger DHHC-type containing 14, [Score=342, Expect=6e-114]} {Mouse: ENSMUSG00000034265, Zdhhc14, zinc finger, DHHC domain containing 14, [Score=340, Expect=6e-113]} {Dmel: FBgn0260941, app, approximated, [Score=338, Expect=7e-114]} {Celegans: WBGene00012948, dhhc-2, Palmitoyltransferase, [Score=223, Expect=8e-69]} {Smed: dd_Smed_v6_9975_0_1, dd_Smed_v6_9975_0_1, [Score=294, Expect=9e-97]} {RNA1509_33436} {RNA1310_5721} {RNA815_5471}

Mlig455_001814 {REF} {Length: 2678} {TRANSSPLICED} {Pfam: DHHC palmitoyltransferase [PF01529.22, score=128.9]} {Human: ENSG00000175048, ZDHHC14, zinc finger DHHC-type containing 14, [Score=341, Expect=1e-113]} {Mouse: ENSMUSG00000034265, Zdhhc14, zinc finger, DHHC domain containing 14, [Score=338, Expect=1e-112]} {Dmel: FBgn0260941, app, approximated, [Score=338, Expect=1e-113]} {Celegans: WBGene00012948, dhhc-2, Palmitoyltransferase, [Score=222, Expect=1e-68]} {Smed: dd_Smed_v6_9975_0_1, dd_Smed_v6_9975_0_1, [Score=293, Expect=2e-96]} {RNA1509_33436} {RNA1310_5721} {RNA815_5471}
51. MligTC455_18642 402 8.37 Mlig455_002696

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.315/0.01369

MFSD13A 0.991 - - - - 0.991 - Mlig455_002696 {REF} {Length: 2673} {Human: ENSG00000138111, MFSD13A, major facilitator superfamily domain containing 13A, [Score=125, Expect=8e-33]} {Mouse: ENSMUSG00000025227, Mfsd13a, major facilitator superfamily domain containing 13a, [Score=124, Expect=2e-32]} {RNA1509_42736} {RNA1310_16644.2} {RNA815_6472.1}
52. MligTC455_26251 74 1.54 Mlig455_042876

Neo: -

Age: -

0.99 - - - - 0.990 - Mlig455_042876 {REF} {Length: 1584} {tRNA: Val(CAC),pseudo, score=36.5} {RNA1509_27801} {RNA1310_2677.1} {RNA815_43902}
53. MligTC455_27139 648 13.49 Mlig455_042308

Neo: -

Age: Down-Down-Up

0.99 - - - - 0.990 - Mlig455_042308 {REF} {Length: 251} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_12443} {RNA1310_15760} {RNA815_80.1}
54. MligTC455_44605 224 4.67 Mlig455_031237

Neo: -

Age: -

Region-enriched R5: 1.873/0.02978

CHRNA9 0.989 - - - - 0.989 - Mlig455_031237 {REF} {Length: 4257} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=144.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=113.8]} {Human: ENSG00000174343, CHRNA9, cholinergic receptor nicotinic alpha 9 subunit, [Score=211, Expect=8e-61]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=201, Expect=2e-56]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=201, Expect=3e-57]} {Mouse: ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=214, Expect=3e-62]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [Score=196, Expect=2e-55]} {Celegans: WBGene00000050, acr-11, AcetylCholine Receptor, [Score=187, Expect=2e-52]} {Smed: dd_Smed_v6_10322_0_1, dd_Smed_v6_10322_0_1, [RH, Score=446, Expect=2e-150]} {RNA1509_46245} {RNA1310_16441} {RNA815_17572}
55. MligTC455_30784 405 8.43 Mlig455_004151, Mlig455_017665, Mlig455_066961

Neo: Irradiation

Age: -

Region-enriched R5: 1.460/0.02276

NEK2, PRR9 0.988 - - - - 0.988 -

Mlig455_004151 {REF} {Length: 4735} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=153.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=80.1]; tRNA synthetases class I (R) [PF00750.21, score=63.6]; DALR anticodon binding domain [PF05746.17, score=41.9]; Kinase-like [PF14531.8, score=23.1]} {Human: ENSG00000117650, NEK2, NIMA related kinase 2, [Score=248, Expect=3e-74]} {Mouse: ENSMUSG00000110797, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=239, Expect=2e-70]; ENSMUSG00000026622, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=239, Expect=2e-70]} {Dmel: FBgn0029970, Nek2, [Score=194, Expect=8e-52]} {Celegans: WBGene00021461, nekl-1, NEK (NEver in mitosis Kinase) Like, [Score=143, Expect=7e-35]} {Smed: dd_Smed_v6_5334_0_1, dd_Smed_v6_5334_0_1, [Score=152, Expect=5e-39]} {RNA1509_41013} {RNA1310_16846} {RNA815_14651}

Mlig455_017665 {REF} {Length: 528} {Human: ENSG00000203783, PRR9, proline rich 9, [Score=44.3, Expect=1e-05]}

Mlig455_066961 {REF} {Length: 4870} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=197.5]; tRNA synthetases class I (R) [PF00750.21, score=167.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=123.5]; DALR anticodon binding domain [PF05746.17, score=52.3]; Kinase-like [PF14531.8, score=22.5]} {Human: ENSG00000117650, NEK2, NIMA related kinase 2, [Score=300, Expect=3e-92]} {Mouse: ENSMUSG00000110797, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=291, Expect=2e-88]; ENSMUSG00000026622, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=291, Expect=2e-88]} {Dmel: FBgn0029970, Nek2, [RH, Score=246, Expect=5e-69]} {Celegans: WBGene00008956, nekl-3, Serine/threonine-protein kinase nekl-3, [Score=163, Expect=2e-44]} {Smed: dd_Smed_v6_5334_0_1, dd_Smed_v6_5334_0_1, [RH, Score=254, Expect=1e-74]} {RNA1509_45663} {RNA1310_16846} {RNA815_14651}
56. MligTC455_33003 169 3.52 Mlig455_026402, Mlig455_052602, Mlig455_052651

Neo: -

Age: Down-Up-Up

ADRB3 0.987 - - - - 0.987 -

Mlig455_026402 {REF} {Length: 2148} {tRNA: Asp(GTC), score=67.3} {Pfam: TNF(Tumour Necrosis Factor) family [PF00229.20, score=25.3]} {RNA1509_29715} {RNA1310_29521.1} {RNA815_35320}

Mlig455_052602 {REF} {Length: 2645} {tRNA: Asp(GTC), score=67.3} {Pfam: TNF(Tumour Necrosis Factor) family [PF00229.20, score=25.3]; Spt20 family [PF12090.10, score=18.3]} {RNA1509_29715} {RNA1310_15320.1} {RNA815_11693.1}

Mlig455_052651 {REF} {Length: 2757} {tRNA: Asp(GTC), score=67.3} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=68.2]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=34.8]; TNF(Tumour Necrosis Factor) family [PF00229.20, score=22.9]} {Human: ENSG00000188778, ADRB3, adrenoceptor beta 3, [Score=60.8, Expect=4e-09]; ENSG00000158748, HTR6, 5-hydroxytryptamine receptor 6, [Score=58.5, Expect=2e-08]} {Mouse: ENSMUSG00000031489, Adrb3, adrenergic receptor, beta 3, [Score=65.5, Expect=9e-11]} {Dmel: FBgn0038063, Octbeta2R, Octopamine beta2 receptor, [Score=53.9, Expect=4e-07]} {Celegans: WBGene00001052, dop-1, DOPamine receptor, [Score=62.8, Expect=5e-10]} {Smed: dd_Smed_v6_24759_0_1, dd_Smed_v6_24759_0_1, [Score=52.8, Expect=6e-07]} {RNA1509_29715} {RNA1310_29521.1} {RNA815_35320}
57. MligTC455_51977 119 2.48 Mlig455_026762, Mlig455_051779

Neo: -

Age: Down-Up-Up

HOXA1 0.987 - - - - 0.987 -

Mlig455_026762 {REF} {Length: 2041} {Pfam: Homeodomain [PF00046.31, score=79.1]} {Human: ENSG00000105991, HOXA1, homeobox A1, [RH, Score=116, Expect=4e-30]; ENSG00000120094, HOXB1, homeobox B1, [RH, Score=114, Expect=8e-30]; ENSG00000128645, HOXD1, homeobox D1, [RH, Score=111, Expect=2e-28]} {Mouse: ENSMUSG00000029844, Hoxa1, homeobox A1, [RH, Score=116, Expect=2e-30]; ENSMUSG00000042448, Hoxd1, homeobox D1, [RH, Score=113, Expect=4e-29]} {Dmel: FBgn0002522, lab, labial, [RH, Score=118, Expect=4e-30]} {Celegans: WBGene00000437, ceh-13, Homeobox protein ceh-13, [RH, Score=85.1, Expect=6e-20]} {Smed: dd_Smed_v6_62255_0_1, dd_Smed_v6_62255_0_1, [RH, Score=121, Expect=3e-34]} {RNA1310_35369} {RNA815_17610}

Mlig455_051779 {REF} {Length: 2283} {Pfam: Homeodomain [PF00046.31, score=80.2]} {Human: ENSG00000105991, HOXA1, homeobox A1, [RH, Score=118, Expect=7e-31]; ENSG00000120094, HOXB1, homeobox B1, [RH, Score=117, Expect=1e-30]; ENSG00000128645, HOXD1, homeobox D1, [RH, Score=114, Expect=3e-29]} {Mouse: ENSMUSG00000029844, Hoxa1, homeobox A1, [RH, Score=118, Expect=4e-31]; ENSMUSG00000018973, Hoxb1, homeobox B1, [RH, Score=116, Expect=1e-30]; ENSMUSG00000042448, Hoxd1, homeobox D1, [RH, Score=115, Expect=5e-30]} {Dmel: FBgn0002522, lab, labial, [RH, Score=120, Expect=8e-31]} {Celegans: WBGene00000437, ceh-13, Homeobox protein ceh-13, [RH, Score=83.6, Expect=2e-19]} {Smed: dd_Smed_v6_62255_0_1, dd_Smed_v6_62255_0_1, [RH, Score=122, Expect=6e-35]} {RNA1509_53134} {RNA1310_35369} {RNA815_17610}
58. MligTC455_54252 51 1.06 Mlig455_027974

Neo: -

Age: -

BBS2 0.987 - - - - 0.987 - Mlig455_027974 {REF} {Length: 2558} {TRANSSPLICED} {Pfam: Ciliary BBSome complex subunit 2, C-terminal [PF14782.8, score=484.2]; Ciliary BBSome complex subunit 2, middle region [PF14783.8, score=136.2]} {Human: ENSG00000125124, BBS2, Bardet-Biedl syndrome 2, [Score=534, Expect=0.0]} {Mouse: ENSMUSG00000031755, Bbs2, Bardet-Biedl syndrome 2 (human), [Score=528, Expect=0.0]} {Celegans: WBGene00000242, bbs-2, Bardet-Biedl syndrome 2 protein homolog, [Score=237, Expect=2e-69]} {Smed: dd_Smed_v6_10186_0_4, dd_Smed_v6_10186_0_4, [Score=458, Expect=4e-154]} {RNA1509_16473} {RNA1310_8004} {RNA815_4076}
59. MligTC455_51941 1054 21.96 Mlig455_002985, Mlig455_055615

Neo: -

Age: -

GLTP 0.986 - - - - 0.986 -

Mlig455_002985 {REF} {Length: 2486} {TRANSSPLICED} {Pfam: Glycolipid transfer protein (GLTP) [PF08718.13, score=112.5]} {Human: ENSG00000139433, GLTP, glycolipid transfer protein, [Score=79.3, Expect=2e-17]} {Mouse: ENSMUSG00000011884, Gltp, glycolipid transfer protein, [Score=79.3, Expect=1e-17]} {Celegans: WBGene00022347, Y82E9BR.14, [RH, Score=83.2, Expect=4e-19]} {Smed: dd_Smed_v6_2621_0_1, dd_Smed_v6_2621_0_1, [RH, Score=115, Expect=1e-31]} {RNA1509_9287} {RNA1310_1228.1} {RNA815_4104.1}

Mlig455_055615 {REF} {Length: 3879} {TRANSSPLICED} {Pfam: Glycolipid transfer protein (GLTP) [PF08718.13, score=112.5]} {Human: ENSG00000139433, GLTP, glycolipid transfer protein, [Score=79.3, Expect=2e-17]} {Mouse: ENSMUSG00000011884, Gltp, glycolipid transfer protein, [Score=79.3, Expect=1e-17]} {Celegans: WBGene00022347, Y82E9BR.14, [RH, Score=83.2, Expect=4e-19]} {Smed: dd_Smed_v6_2621_0_1, dd_Smed_v6_2621_0_1, [RH, Score=115, Expect=1e-31]} {RNA1509_9287} {RNA1310_1228.1} {RNA815_4104.1}
60. MligTC455_05406 86 1.79 Mlig455_010183, Mlig455_058666

Neo: -

Age: -

0.985 - - - - 0.985 -

Mlig455_010183 {REF} {Length: 212} {NoTransDecoderORF} {RNA1509_45237} {RNA1310_107013} {RNA815_30992}

Mlig455_058666 {REF} {Length: 234} {NoTransDecoderORF} {RNA1509_45237} {RNA1310_107013} {RNA815_30992}
61. MligTC455_27518 84 1.74 Mlig455_000067, Mlig455_000602

Neo: -

Age: -

0.985 - - - - 0.985 -

Mlig455_000067 {REF} {Length: 887} {Pfam: SAP domain [PF02037.29, score=41.1]; Phage integrase family [PF00589.24, score=27.1]} {RNA1509_11319} {RNA1310_26129} {RNA815_6444}

Mlig455_000602 {REF} {Length: 2043} {Pfam: SAP domain [PF02037.29, score=34.0]; Phage integrase family [PF00589.24, score=27.0]} {RNA1509_11319} {RNA1310_18293} {RNA815_9177.1}
62. MligTC455_37352 210 4.37 Mlig455_012059

Neo: Int S/G2/M

Age: -

RNASEH2A 0.985 - - - - 0.985 - Mlig455_012059 {REF} {Length: 1775} {TRANSSPLICED} {Pfam: Ribonuclease HII [PF01351.20, score=153.5]} {Human: ENSG00000104889, RNASEH2A, ribonuclease H2 subunit A, [RH, Score=232, Expect=4e-74]} {Mouse: ENSMUSG00000052926, Rnaseh2a, ribonuclease H2, large subunit, [RH, Score=234, Expect=5e-75]} {Dmel: FBgn0031252, CG13690, [RH, Score=226, Expect=1e-71]} {Celegans: WBGene00004383, rnh-2, Ribonuclease H2 subunit A, [RH, Score=231, Expect=3e-74]} {Smed: dd_Smed_v6_10404_0_1, dd_Smed_v6_10404_0_1, [RH, Score=261, Expect=8e-86]} {RNA1509_29004} {RNA1310_30632} {RNA815_10850}
63. MligTC455_43364 95 1.98 Mlig455_002247

Neo: -

Age: -

0.985 - - - - 0.985 - Mlig455_002247 {REF} {Length: 6158} {TRANSSPLICED} {Pfam: Putative zinc-finger domain [PF10650.11, score=22.5]} {Smed: dd_Smed_v6_9636_0_1, dd_Smed_v6_9636_0_1, [RH, Score=126, Expect=2e-29]} {RNA1509_29369} {RNA1310_1698} {RNA815_876.1}
64. MligTC455_46311 178 3.71 Mlig455_024248

Neo: -

Age: Down-Up-Down

NISCH 0.985 - - - - 0.985 - Mlig455_024248 {REF} {Length: 4779} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=44.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=40.7]; Leucine rich repeat [PF13855.8, score=33.7]; PX domain [PF00787.26, score=25.6]} {Human: ENSG00000010322, NISCH, nischarin, [Score=298, Expect=8e-91]} {Mouse: ENSMUSG00000021910, Nisch, nischarin, [Score=286, Expect=1e-86]} {Dmel: FBgn0033996, CG11807, [Score=201, Expect=7e-56]} {Celegans: WBGene00008750, F13E9.1, [Score=188, Expect=2e-51]} {Smed: dd_Smed_v6_8533_0_5, dd_Smed_v6_8533_0_5, [Score=196, Expect=4e-54]} {RNA1509_31748} {RNA1310_12578} {RNA815_13327}
65. MligTC455_40824 485 10.11 Mlig455_039440, Mlig455_039485

Neo: -

Age: -

0.984 - - - - 0.984 -

Mlig455_039440 {REF} {Length: 2307} {TRANSSPLICED} {RNA1310_26898.1} {RNA815_6829.1}

Mlig455_039485 {REF} {Length: 2230} {TRANSSPLICED} {RNA1310_26898.1} {RNA815_6829.1}
66. MligTC455_43362 93 1.95 Mlig455_002148

Neo: -

Age: -

0.984 - - - - 0.984 - Mlig455_002148 {REF} {Length: 2843} {TRANSSPLICED} {Smed: dd_Smed_v6_9636_0_1, dd_Smed_v6_9636_0_1, [RH, Score=127, Expect=1e-30]} {RNA1509_37248} {RNA1310_12152.1} {RNA815_8090}
67. MligTC455_47844 25 0.52 Mlig455_054684

Neo: -

Age: logFC(26M/2M)=-0.260

RPGRIP1L 0.984 - - - - 0.984 - Mlig455_054684 {REF} {Length: 3774} {TRANSSPLICED} {Human: ENSG00000103494, RPGRIP1L, RPGRIP1 like, [Score=115, Expect=5e-26]} {Mouse: ENSMUSG00000033282, Rpgrip1l, Rpgrip1-like, [Score=111, Expect=5e-25]} {Smed: dd_Smed_v6_11425_0_1, dd_Smed_v6_11425_0_1, [Score=143, Expect=1e-35]} {RNA1509_12953} {RNA1310_4375.1} {RNA815_1280}
68. MligTC455_52338 341 7.1 Mlig455_008924

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.465

C2orf76 0.984 - - - - 0.984 - Mlig455_008924 {REF} {Length: 2124} {TRANSSPLICED} {Pfam: Uncharacterized conserved protein (DUF2340) [PF10209.11, score=127.4]} {Human: ENSG00000186132, C2orf76, chromosome 2 open reading frame 76, [RH, Score=97.1, Expect=2e-26]} {Mouse: ENSMUSG00000026388, 3110009E18Rik, RIKEN cDNA 3110009E18 gene, [RH, Score=92.0, Expect=1e-24]} {RNA1509_25259, RNA1509_33285} {RNA1310_9901.1, RNA1509_25259, RNA1509_33285} {RNA1509_25259, RNA1509_33285, RNA815_28452}
69. MligTC455_23555 418 8.71 Mlig455_013595

Neo: -

Age: -

DNAJC4 0.983 - - - - 0.983 - Mlig455_013595 {REF} {Length: 2081} {TRANSSPLICED} {Pfam: DnaJ domain [PF00226.33, score=67.2]} {Human: ENSG00000110011, DNAJC4, DnaJ heat shock protein family (Hsp40) member C4, [RH, Score=67.4, Expect=5e-13]; ENSG00000176410, DNAJC30, DnaJ heat shock protein family (Hsp40) member C30, [RH, Score=64.7, Expect=4e-12]} {Mouse: ENSMUSG00000014905, Dnajb9, DnaJ heat shock protein family (Hsp40) member B9, [Score=67.4, Expect=3e-13]} {Dmel: FBgn0037544, CG11035, [Score=65.5, Expect=1e-12]} {Celegans: WBGene00001022, dnj-4, DNaJ domain (Prokaryotic heat shock protein), [RH, Score=58.9, Expect=3e-10]} {Smed: dd_Smed_v6_3393_0_1, dd_Smed_v6_3393_0_1, [RH, Score=72.0, Expect=1e-15]} {RNA1509_17877, RNA1509_20487, RNA1509_27055, RNA1509_35237, RNA1509_47036, RNA1509_54606, RNA1509_56854} {RNA1310_22951, RNA1509_17877, RNA1509_20487, RNA1509_27055, RNA1509_35237, RNA1509_47036, RNA1509_54606, RNA1509_56854} {RNA1509_17877, RNA1509_20487, RNA1509_27055, RNA1509_35237, RNA1509_47036, RNA1509_54606, RNA1509_56854, RNA815_9786}
70. MligTC455_43178 271 5.65 Mlig455_041380

Neo: -

Age: -

0.983 - - - - 0.983 - Mlig455_041380 {REF} {Length: 804} {RNA1509_7702} {RNA1310_9214} {RNA815_28262.1}
71. MligTC455_47301 209 4.35 Mlig455_049133

Neo: -

Age: -

ASXL2 0.983 - - - - 0.983 - Mlig455_049133 {REF} {Length: 3735} {TRANSSPLICED} {Pfam: Asx homology domain [PF13919.8, score=57.7]} {Human: ENSG00000143970, ASXL2, ASXL transcriptional regulator 2, [RH, Score=82.8, Expect=1e-15]} {Mouse: ENSMUSG00000037486, Asxl2, additional sex combs like 2, transcriptional regulator, [RH, Score=78.6, Expect=6e-15]} {Smed: dd_Smed_v6_8139_0_1, dd_Smed_v6_8139_0_1, [Score=52.4, Expect=1e-06]} {RNA1509_12997} {RNA1310_6363, RNA1509_12997} {RNA1509_12997, RNA815_24627.1}
72. MligTC455_49284 156 3.24 Mlig455_054679

Neo: -

Age: Down-Up-Down

0.983 - - - - 0.983 - Mlig455_054679 {REF} {Length: 1923} {NoTransDecoderORF} {RNA1310_45917.1} {RNA815_22709}
73. MligTC455_51732 90 1.87 Mlig455_035307

Neo: Germline

Age: Up-Down-Down

Region-specific R4: 5.988

0.983 - - - - 0.983 - Mlig455_035307 {REF} {Length: 7790} {Pfam: Helical bimodular sensor domain [PF16591.7, score=108.0]; Alpha-2-macroglobulin RAP, C-terminal domain [PF06401.13, score=57.4]; Importin repeat 6 [PF18829.3, score=18.8]} {RNA1509_1390, RNA1509_23464, RNA1509_34475} {RNA1310_40189, RNA1509_1390, RNA1509_23464, RNA1509_34475} {RNA1509_1390, RNA1509_23464, RNA1509_34475, RNA815_35940}
74. MligTC455_53052 370 7.7 Mlig455_062079

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.857

LDB3 0.983 - - - - 0.983 - Mlig455_062079 {REF} {Length: 3738} {Pfam: PDZ domain [PF00595.26, score=45.7]; PDZ domain [PF17820.3, score=35.5]; LIM domain [PF00412.24, score=25.7]; PDZ domain [PF13180.8, score=18.9]} {Human: ENSG00000122367, LDB3, LIM domain binding 3, [Score=67.0, Expect=3e-12]; ENSG00000196923, PDLIM7, PDZ and LIM domain 7, [Score=65.1, Expect=5e-11]} {Mouse: ENSMUSG00000021493, Pdlim7, PDZ and LIM domain 7, [Score=67.0, Expect=7e-12]; ENSMUSG00000021798, Ldb3, LIM domain binding 3, [Score=66.6, Expect=6e-12]; ENSMUSG00000028273, Pdlim5, PDZ and LIM domain 5, [Score=65.5, Expect=2e-11]} {Dmel: FBgn0265991, Zasp52, Z band alternatively spliced PDZ-motif protein 52, [Score=108, Expect=8e-26]} {Smed: dd_Smed_v6_4618_0_1, dd_Smed_v6_4618_0_1, [Score=150, Expect=4e-43]} {RNA1509_27138} {RNA1310_17148, RNA1509_27138} {RNA1509_27138, RNA815_14040.2}
75. MligTC455_26117 63 1.32 Mlig455_009396

Neo: -

Age: -

0.982 - - - - 0.982 - Mlig455_009396 {REF} {Length: 3615} {RNA1509_28486} {RNA1310_24343.1} {RNA815_8096}
76. MligTC455_27513 326 6.8 Mlig455_027937

Neo: -

Age: logFC(26M/2M)=-0.593

MAP3K4 0.982 - - - - 0.982 - Mlig455_027937 {REF} {Length: 2685} {Pfam: Protein kinase domain [PF00069.27, score=165.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=123.4]; Ankyrin repeats (3 copies) [PF12796.9, score=78.4]; Ankyrin repeats (many copies) [PF13637.8, score=58.3]; Ankyrin repeat [PF13606.8, score=56.2]; Ankyrin repeats (many copies) [PF13857.8, score=46.5]; Ankyrin repeat [PF00023.32, score=40.7]; Fungal protein kinase [PF17667.3, score=27.5]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=132, Expect=4e-31]} {Mouse: ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=128, Expect=6e-30]; ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=123, Expect=2e-28]; ENSMUSG00000031303, Map3k15, mitogen-activated protein kinase kinase kinase 15, [Score=122, Expect=3e-28]} {Dmel: FBgn0024329, Mekk1, [Score=126, Expect=2e-29]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=137, Expect=4e-33]} {Smed: dd_Smed_v6_4849_0_1, dd_Smed_v6_4849_0_1, [Score=112, Expect=2e-25]} {RNA1509_27731} {RNA1310_10050} {RNA815_9449.1}
77. MligTC455_33505 489 10.19 Mlig455_057519

Neo: Irradiation

Age: -

XAB2 0.982 - - - - 0.982 - Mlig455_057519 {REF} {Length: 3105} {Pfam: Tetratricopeptide repeat [PF13428.8, score=64.4]; Tetratricopeptide repeat [PF14559.8, score=40.5]; Suppressor of forked protein (Suf) [PF05843.16, score=38.4]; Tetratricopeptide repeat [PF13429.8, score=38.2]; Tetratricopeptide repeat [PF07719.19, score=33.6]; Tetratricopeptide repeat [PF13424.8, score=27.5]; NRDE-2, necessary for RNA interference [PF08424.12, score=22.1]; Mad3/BUB1 homology region 1 [PF08311.14, score=21.3]} {Human: ENSG00000076924, XAB2, XPA binding protein 2, [RH, Score=873, Expect=0.0]} {Mouse: ENSMUSG00000019470, Xab2, XPA binding protein 2, [RH, Score=873, Expect=0.0]} {Dmel: FBgn0033859, fand, fandango, [RH, Score=868, Expect=0.0]} {Celegans: WBGene00016837, syf-1, [RH, Score=758, Expect=0.0]} {Smed: dd_Smed_v6_6473_0_1, dd_Smed_v6_6473_0_1, [RH, Score=712, Expect=0.0]} {RNA1509_33245, RNA1509_5006, RNA1509_55462} {RNA1310_2111.2, RNA1509_33245, RNA1509_55462} {RNA1509_33245, RNA1509_55462, RNA815_1651.1}
78. MligTC455_35281 315 6.56 Mlig455_069275

Neo: Int S/G2/M

Age: -

0.982 - - - - 0.982 - Mlig455_069275 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: MYND finger [PF01753.20, score=30.8]} {RNA1509_40766} {RNA1310_18463, RNA1509_40766} {RNA1509_40766, RNA815_10924}
79. MligTC455_40524 394 8.2 Mlig455_064858

Neo: Irradiation

Age: -

RECQL5 0.982 - - - - 0.982 - Mlig455_064858 {REF} {Length: 4472} {TRANSSPLICED} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=72.4]; Helicase conserved C-terminal domain [PF00271.33, score=55.2]; RecQ zinc-binding [PF16124.7, score=38.7]; Type III restriction enzyme, res subunit [PF04851.17, score=23.2]} {Human: ENSG00000108469, RECQL5, RecQ like helicase 5, [RH, Score=462, Expect=2e-145]} {Mouse: ENSMUSG00000020752, Recql5, RecQ protein-like 5, [RH, Score=452, Expect=5e-142]} {Dmel: FBgn0027375, RecQ5, RecQ5 helicase, [RH, Score=415, Expect=1e-127]} {Celegans: WBGene00004322, rcq-5, ReCQ DNA helicase family, [RH, Score=400, Expect=1e-124]} {Smed: dd_Smed_v6_11145_0_4, dd_Smed_v6_11145_0_4, [RH, Score=477, Expect=4e-153]} {RNA1509_13588} {RNA1310_3375} {RNA815_18308}
80. MligTC455_48346 528 11 Mlig455_016751

Neo: -

Age: logFC(26M/2M)=0.316

0.982 - - - - 0.982 - Mlig455_016751 {REF} {Length: 2598} {TRANSSPLICED} {RNA1509_12740, RNA1509_39294} {RNA1310_9917, RNA1509_39294} {RNA1509_39294, RNA815_1952.1}
81. MligTC455_42225 20 0.41 Mlig455_042394

Neo: -

Age: -

CPQ 0.981 - - - - 0.981 - Mlig455_042394 {REF} {Length: 1554} {TRANSSPLICED} {Pfam: Peptidase family M28 [PF04389.19, score=87.4]; Peptidase family M20/M25/M40 [PF01546.30, score=27.3]; PA domain [PF02225.24, score=20.6]} {Human: ENSG00000104324, CPQ, carboxypeptidase Q, [RH, Score=370, Expect=7e-124]} {Mouse: ENSMUSG00000039007, Cpq, carboxypeptidase Q, [RH, Score=374, Expect=2e-125]} {Celegans: WBGene00020082, gcp-2.1, Glutamate carboxypeptidase 2 homolog, [Score=51.2, Expect=1e-06]} {RNA1509_11715} {RNA1310_19598.1, RNA1509_11715} {RNA1509_11715, RNA815_7922}
82. MligTC455_44777 598 12.45 Mlig455_065381

Neo: -

Age: logFC(26M/2M)=0.209

SPART 0.981 - - - - 0.981 - Mlig455_065381 {REF} {Length: 2661} {TRANSSPLICED} {Pfam: Senescence-associated protein [PF06911.14, score=58.7]} {Human: ENSG00000133104, SPART, spartin, [Score=56.2, Expect=9e-08]} {Mouse: ENSMUSG00000036580, Spg20, spastic paraplegia 20, spartin (Troyer syndrome) homolog (human), [Score=100, Expect=9e-22]} {RNA1509_10450} {RNA1310_9098} {RNA815_5367}
83. MligTC455_46704 1062 22.12 Mlig455_007999

Neo: -

Age: -

DNAJB11 0.981 - - - - 0.981 - Mlig455_007999 {REF} {Length: 3215} {TRANSSPLICED} {Pfam: DnaJ domain [PF00226.33, score=93.3]} {Human: ENSG00000090520, DNAJB11, DnaJ heat shock protein family (Hsp40) member B11, [Score=85.1, Expect=9e-18]; ENSG00000147570, DNAJC5B, DnaJ heat shock protein family (Hsp40) member C5 beta, [Score=83.2, Expect=4e-18]; ENSG00000140403, DNAJA4, DnaJ heat shock protein family (Hsp40) member A4, [Score=82.0, Expect=2e-17]; ENSG00000179407, DNAJB8, DnaJ heat shock protein family (Hsp40) member B8, [Score=80.9, Expect=6e-17]} {Mouse: ENSMUSG00000090202, 4930503B20Rik, RIKEN cDNA 4930503B20 gene, [RH, Score=82.4, Expect=1e-17]} {Dmel: FBgn0004179, Csp, Cysteine string protein, [Score=79.0, Expect=1e-16]} {Celegans: WBGene00001034, dnj-16, DNaJ domain (Prokaryotic heat shock protein), [RH, Score=335, Expect=5e-113]} {Smed: dd_Smed_v6_1779_0_1, dd_Smed_v6_1779_0_1, [Score=80.1, Expect=2e-17]} {RNA1509_12015, RNA1509_14449, RNA1509_29413, RNA1509_55977} {RNA1310_24689, RNA1509_12015, RNA1509_14449, RNA1509_29413, RNA1509_55977} {RNA1509_12015, RNA1509_14449, RNA1509_29413, RNA1509_55977, RNA815_10612}
84. MligTC455_51810 292 6.09 Mlig455_055914

Neo: -

Age: logFC(26M/2M)=0.322

RAB29 0.981 - - - - 0.981 - Mlig455_055914 {REF} {Length: 1941} {Pfam: Ras family [PF00071.24, score=68.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=19.6]} {Human: ENSG00000117280, RAB29, RAB29, member RAS oncogene family, [RH, Score=123, Expect=3e-36]} {Mouse: ENSMUSG00000019832, Rab32, RAB32, member RAS oncogene family, [Score=127, Expect=9e-37]} {Dmel: FBgn0002567, Rab32, [Score=112, Expect=3e-31]} {Celegans: WBGene00011083, glo-1, Gut granule LOss; Rab GTPase GLO-1, [Score=106, Expect=4e-29]} {Smed: dd_Smed_v6_2915_0_1, dd_Smed_v6_2915_0_1, [Score=134, Expect=3e-40]} {RNA1509_54279} {RNA1310_15012} {RNA815_20567}
85. MligTC455_12881 431 8.97 Mlig455_069109

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.318

CYLD 0.98 - - - - 0.980 - Mlig455_069109 {REF} {Length: 5402} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=29.6]} {Human: ENSG00000083799, CYLD, CYLD lysine 63 deubiquitinase, [RH, Score=296, Expect=2e-86]} {Mouse: ENSMUSG00000036712, Cyld, CYLD lysine 63 deubiquitinase, [Score=287, Expect=3e-83]} {Dmel: FBgn0032210, CYLD, Cylindromatosis, [RH, Score=323, Expect=2e-99]} {Celegans: WBGene00009594, cyld-1, CYLinDromatosis (Human disease gene) homolog, [RH, Score=210, Expect=1e-56]} {Smed: dd_Smed_v6_3043_0_1, dd_Smed_v6_3043_0_1, [RH, Score=158, Expect=8e-40]} {RNA1509_18711, RNA1509_19340, RNA1509_34756, RNA1509_35847} {RNA1310_5613.1, RNA1509_19340, RNA1509_34756, RNA1509_35847} {RNA1509_19340, RNA1509_34756, RNA1509_35847, RNA815_1700}
86. MligTC455_21535 290 6.05 Mlig455_014603

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

0.98 - - - - 0.980 - Mlig455_014603 {REF} {Length: 2779} {Pfam: Amnionless [PF14828.8, score=88.5]} {RNA1509_36645} {RNA1310_11582, RNA1509_36645} {RNA1509_36645, RNA815_5314}
87. MligTC455_25772 151 3.15 Mlig455_067364

Neo: -

Age: -

0.98 - - - - 0.980 - Mlig455_067364 {REF} {Length: 3815} {RNA1509_5822} {RNA1310_3594} {RNA815_4411}
88. MligTC455_33926 263 5.47 Mlig455_048965

Neo: -

Age: Down-Down-Up

PPIL2 0.98 - - - - 0.980 - Mlig455_048965 {REF} {Length: 2574} {TRANSSPLICED} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=170.4]; Rtf2 RING-finger [PF04641.14, score=25.1]} {Human: ENSG00000100023, PPIL2, peptidylprolyl isomerase like 2, [RH, Score=503, Expect=5e-174]} {Mouse: ENSMUSG00000022771, Ppil2, peptidylprolyl isomerase (cyclophilin)-like 2, [RH, Score=492, Expect=3e-170]} {Dmel: FBgn0034109, CG7747, [RH, Score=511, Expect=7e-178]} {Celegans: WBGene00000880, cyn-4, Peptidyl-prolyl cis-trans isomerase 4, [RH, Score=439, Expect=2e-149]} {Smed: dd_Smed_v6_4217_0_1, dd_Smed_v6_4217_0_1, [RH, Score=452, Expect=2e-154]} {RNA1509_9537} {RNA1310_15337, RNA1509_9537} {RNA1509_9537, RNA815_4990}
89. MligTC455_07006 53 1.11 Mlig455_009073

Neo: -

Age: -

0.979 - - - - 0.979 - Mlig455_009073 {REF} {Length: 1805} {NoTransDecoderORF} {RNA1509_56630} {RNA1310_27227, RNA1509_56630} {RNA1509_56630, RNA815_16347}
90. MligTC455_10485 94 1.96 Mlig455_042510

Neo: Irradiation

Age: Up-Down-Down

Region-specific R4: 5.918

Region-enriched R4: 3.900/0.00781

0.979 - - - - 0.979 - Mlig455_042510 {REF} {Length: 3597} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=120.5]} {Smed: dd_Smed_v6_15195_0_1, dd_Smed_v6_15195_0_1, [Score=50.8, Expect=2e-06]} {RNA1509_29265} {RNA1310_22628.2} {RNA815_24829.1}
91. MligTC455_15882 190 3.96 Mlig455_053240, Mlig455_066369

Neo: -

Age: -

RAC1 0.979 - - - - 0.979 -

Mlig455_053240 {REF} {Length: 1362} {Pfam: Ras family [PF00071.24, score=172.4]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=79.6]; ADP-ribosylation factor family [PF00025.23, score=31.1]} {Human: ENSG00000136238, RAC1, Rac family small GTPase 1, [Score=274, Expect=7e-94]; ENSG00000128340, RAC2, Rac family small GTPase 2, [Score=271, Expect=9e-93]} {Mouse: ENSMUSG00000001847, Rac1, Rac family small GTPase 1, [Score=274, Expect=5e-94]; ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [Score=269, Expect=3e-92]} {Dmel: FBgn0010333, Rac1, [Score=270, Expect=6e-93]} {Celegans: WBGene00000424, ced-10, Ras-related protein ced-10, [Score=271, Expect=3e-93]} {Smed: dd_Smed_v6_610_0_1, dd_Smed_v6_610_0_1, [Score=258, Expect=4e-88]} {RNA1310_27386.2} {RNA815_17940}

Mlig455_066369 {REF} {Length: 1360} {Pfam: Ras family [PF00071.24, score=172.4]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=79.6]; ADP-ribosylation factor family [PF00025.23, score=31.1]} {Human: ENSG00000136238, RAC1, Rac family small GTPase 1, [Score=274, Expect=7e-94]; ENSG00000128340, RAC2, Rac family small GTPase 2, [Score=271, Expect=9e-93]} {Mouse: ENSMUSG00000001847, Rac1, Rac family small GTPase 1, [Score=274, Expect=5e-94]; ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [Score=269, Expect=3e-92]} {Dmel: FBgn0010333, Rac1, [Score=270, Expect=6e-93]} {Celegans: WBGene00000424, ced-10, Ras-related protein ced-10, [Score=271, Expect=3e-93]} {Smed: dd_Smed_v6_610_0_1, dd_Smed_v6_610_0_1, [Score=258, Expect=4e-88]} {RNA1310_27386.2} {RNA815_17940}
92. MligTC455_17484 291 6.07 Mlig455_011788, Mlig455_013019

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.389

ARNT, ARNT2 0.979 - - - - 0.979 -

Mlig455_011788 {REF} {Length: 3032} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=21.7} {Pfam: PAS fold [PF08447.14, score=49.6]; Helix-loop-helix DNA-binding domain [PF00010.28, score=49.1]; PAS fold [PF00989.27, score=46.7]; PAS fold [PF08448.12, score=32.6]; PAS domain [PF14598.8, score=28.5]; PAS domain [PF13426.9, score=20.3]} {Human: ENSG00000143437, ARNT, aryl hydrocarbon receptor nuclear translocator, [RH, Score=338, Expect=6e-106]; ENSG00000172379, ARNT2, aryl hydrocarbon receptor nuclear translocator 2, [RH, Score=335, Expect=3e-105]} {Mouse: ENSMUSG00000015522, Arnt, aryl hydrocarbon receptor nuclear translocator, [RH, Score=337, Expect=2e-105]; ENSMUSG00000015709, Arnt2, aryl hydrocarbon receptor nuclear translocator 2, [RH, Score=333, Expect=9e-105]} {Dmel: FBgn0264075, tgo, tango, [RH, Score=362, Expect=2e-116]} {Celegans: WBGene00000095, aha-1, Aryl hydrocarbon receptor nuclear translocator homolog, [RH, Score=278, Expect=9e-87]} {Smed: dd_Smed_v6_9171_0_1, dd_Smed_v6_9171_0_1, [RH, Score=378, Expect=2e-122]} {RNA1509_46779} {RNA1310_12680, RNA1509_46779} {RNA1509_46779, RNA815_8463}

Mlig455_013019 {REF} {Length: 3005} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=21.7} {Pfam: PAS fold [PF08447.14, score=49.2]; PAS fold [PF00989.27, score=46.0]; PAS fold [PF08448.12, score=30.2]; PAS domain [PF14598.8, score=27.7]; Helix-loop-helix DNA-binding domain [PF00010.28, score=22.7]} {Human: ENSG00000172379, ARNT2, aryl hydrocarbon receptor nuclear translocator 2, [Score=303, Expect=6e-94]; ENSG00000143437, ARNT, aryl hydrocarbon receptor nuclear translocator, [Score=301, Expect=2e-92]} {Mouse: ENSMUSG00000015522, Arnt, aryl hydrocarbon receptor nuclear translocator, [RH, Score=298, Expect=1e-91]} {Dmel: FBgn0264075, tgo, tango, [Score=324, Expect=3e-103]} {Celegans: WBGene00000095, aha-1, Aryl hydrocarbon receptor nuclear translocator homolog, [Score=242, Expect=6e-74]} {Smed: dd_Smed_v6_9171_0_1, dd_Smed_v6_9171_0_1, [Score=324, Expect=9e-103]} {RNA1509_20140} {RNA1310_12680} {RNA815_8463}
93. MligTC455_19655 475 9.9 Mlig455_064127

Neo: -

Age: -

0.979 - - - - 0.979 - Mlig455_064127 {REF} {Length: 378} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_20237} {RNA1310_90847, RNA1509_20237} {RNA1509_20237, RNA815_48534}
94. MligTC455_33351 132 2.75 Mlig455_064999

Neo: -

Age: Up-Down-Up

TRPM3 0.979 - - - - 0.979 - Mlig455_064999 {REF} {Length: 9865} {Pfam: SLOG in TRPM [PF18139.3, score=151.7]; Ion transport protein [PF00520.33, score=58.8]; SLOG in TRPM, prokaryote [PF18171.3, score=51.5]; Ankyrin repeats (3 copies) [PF12796.9, score=47.7]; Ankyrin repeat [PF00023.32, score=36.7]; Ankyrin repeats (many copies) [PF13637.8, score=33.2]; Ankyrin repeat [PF13606.8, score=28.1]; Ankyrin repeats (many copies) [PF13857.8, score=26.9]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=251, Expect=2e-66]; ENSG00000070985, TRPM5, transient receptor potential cation channel subfamily M member 5, [Score=248, Expect=3e-66]; ENSG00000142185, TRPM2, transient receptor potential cation channel subfamily M member 2, [Score=247, Expect=3e-65]; ENSG00000274965, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=241, Expect=2e-63]; ENSG00000134160, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=241, Expect=2e-63]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=257, Expect=3e-68]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=229, Expect=8e-60]} {Celegans: WBGene00001795, gtl-1, GTL-1; Gon-Two Like (TRP subfamily), [Score=203, Expect=5e-52]} {Smed: dd_Smed_v6_17981_0_1, dd_Smed_v6_17981_0_1, [Score=619, Expect=0.0]} {RNA1509_14127, RNA1509_52037} {RNA1310_477.1, RNA1509_14127, RNA1509_52037} {RNA1509_14127, RNA1509_52037, RNA815_12146}
95. MligTC455_43439 189 3.93 Mlig455_055229, Mlig455_055327

Neo: -

Age: -

RNF170 0.979 - - - - 0.979 -

Mlig455_055229 {REF} {Length: 1491} {Pfam: Protein of unknown function (DUF1232) [PF06803.14, score=36.4]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=32.3]; Ring finger domain [PF13639.8, score=31.5]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=30.5]; zinc-RING finger domain [PF14634.8, score=27.4]; RING-type zinc-finger [PF13445.8, score=26.0]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=24.9]; zinc finger of C3HC4-type, RING [PF15227.8, score=22.2]; Baculovirus immediate-early protein (IE-0) [PF05290.13, score=18.8]} {Human: ENSG00000120925, RNF170, ring finger protein 170, [RH, Score=135, Expect=7e-39]} {Mouse: ENSMUSG00000013878, Rnf170, ring finger protein 170, [RH, Score=135, Expect=4e-39]} {Smed: dd_Smed_v6_7918_0_1, dd_Smed_v6_7918_0_1, [RH, Score=126, Expect=5e-36]} {RNA1509_22235} {RNA1310_9312.1} {RNA815_10897}

Mlig455_055327 {REF} {Length: 1662} {Pfam: Protein of unknown function (DUF1232) [PF06803.14, score=36.0]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=32.1]; Ring finger domain [PF13639.8, score=30.6]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=30.4]; zinc-RING finger domain [PF14634.8, score=27.3]; RING-type zinc-finger [PF13445.8, score=25.7]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=24.8]; zinc finger of C3HC4-type, RING [PF15227.8, score=21.7]} {Human: ENSG00000120925, RNF170, ring finger protein 170, [RH, Score=137, Expect=5e-39]} {Mouse: ENSMUSG00000013878, Rnf170, ring finger protein 170, [RH, Score=137, Expect=4e-39]} {Smed: dd_Smed_v6_7918_0_1, dd_Smed_v6_7918_0_1, [RH, Score=127, Expect=5e-36]} {RNA1509_22235} {RNA1310_9312.1} {RNA815_10897}
96. MligTC455_04596 69 1.43 Mlig455_030686

Neo: -

Age: Up-Down-Up

0.978 - - - - 0.978 - Mlig455_030686 {REF} {Length: 1197} {Pfam: NIPSNAP [PF07978.15, score=75.2]} {Mouse: ENSMUSG00000015247, Nipsnap3b, nipsnap homolog 3B, [RH, Score=73.9, Expect=1e-15]} {RNA1509_38571} {RNA1310_21189.1} {RNA815_13886}
97. MligTC455_10466 45 0.95 Mlig455_044211

Neo: -

Age: -

0.978 - - - - 0.978 - Mlig455_044211 {REF} {Length: 922} {NoTransDecoderORF} {RNA1509_11558} {RNA1310_9532} {RNA815_7243}
98. MligTC455_10540 305 6.35 Mlig455_027490

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.995

0.978 - - - - 0.978 - Mlig455_027490 {REF} {Length: 877} {NoTransDecoderORF} {RNA1509_32737} {RNA1310_50694, RNA1509_32737} {RNA1509_32737, RNA815_25499}
99. MligTC455_12782 51 1.07 Mlig455_012991

Neo: -

Age: -

0.978 - - - - 0.978 - Mlig455_012991 {REF} {Length: 1473} {TRANSSPLICED} {RNA1509_56473} {RNA1310_22716.1, RNA1509_56473} {RNA1509_56473, RNA815_10095.1}
100. MligTC455_15802 480 9.99 Mlig455_025699, Mlig455_025724

Neo: Germline

Age: Down-Up-Up

Region-enriched R4: 2.398/0.02873

0.978 - - - - 0.978 -

Mlig455_025699 {REF} {Length: 391} {TRANSSPLICED} {RNA1509_45172} {RNA1310_78659, RNA1509_45172} {RNA1509_45172, RNA815_42736}

Mlig455_025724 {REF} {Length: 391} {TRANSSPLICED} {RNA1509_45172} {RNA1310_78659} {RNA815_42736}

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