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Results for MligTC455_25987

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_25987 1137 23.68 Mlig455_045677, Mlig455_045688

Neo: -

Age: -

Region-enriched R4: 1.034/0.01831

AGPAT4

Mlig455_045677 {REF} {Length: 4133} {TRANSSPLICED} {Pfam: Acyltransferase C-terminus [PF16076.7, score=72.0]; Acyltransferase [PF01553.23, score=65.1]} {Human: ENSG00000026652, AGPAT4, 1-acylglycerol-3-phosphate O-acyltransferase 4, [RH, Score=281, Expect=2e-91]; ENSG00000160216, AGPAT3, 1-acylglycerol-3-phosphate O-acyltransferase 3, [RH, Score=270, Expect=3e-87]} {Mouse: ENSMUSG00000001211, Agpat3, 1-acylglycerol-3-phosphate O-acyltransferase 3, [RH, Score=273, Expect=1e-88]; ENSMUSG00000023827, Agpat4, 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta), [RH, Score=265, Expect=3e-85]} {Dmel: FBgn0036623, CG4729, [RH, Score=232, Expect=1e-72]} {Celegans: WBGene00044631, bus-18, [Score=106, Expect=2e-25]} {Smed: dd_Smed_v6_5643_0_1, dd_Smed_v6_5643_0_1, [RH, Score=228, Expect=5e-71]} {RNA1509_29014, RNA1509_52614} {RNA1310_17321.1, RNA1509_52614} {RNA1509_52614, RNA815_7698}

Mlig455_045688 {REF} {Length: 4198} {TRANSSPLICED} {Pfam: Acyltransferase C-terminus [PF16076.7, score=72.0]; Acyltransferase [PF01553.23, score=65.1]} {Human: ENSG00000026652, AGPAT4, 1-acylglycerol-3-phosphate O-acyltransferase 4, [RH, Score=281, Expect=2e-91]; ENSG00000160216, AGPAT3, 1-acylglycerol-3-phosphate O-acyltransferase 3, [RH, Score=270, Expect=3e-87]} {Mouse: ENSMUSG00000001211, Agpat3, 1-acylglycerol-3-phosphate O-acyltransferase 3, [RH, Score=273, Expect=1e-88]; ENSMUSG00000023827, Agpat4, 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta), [RH, Score=265, Expect=3e-85]} {Dmel: FBgn0036623, CG4729, [RH, Score=232, Expect=1e-72]} {Celegans: WBGene00044631, bus-18, [Score=106, Expect=2e-25]} {Smed: dd_Smed_v6_5643_0_1, dd_Smed_v6_5643_0_1, [RH, Score=228, Expect=5e-71]} {RNA1509_13486, RNA1509_29014, RNA1509_45027, RNA1509_50911} {RNA1310_17321.1, RNA1509_13486, RNA1509_29014, RNA1509_45027, RNA1509_50911} {RNA1509_13486, RNA1509_29014, RNA1509_45027, RNA1509_50911, RNA815_7698}

Cumulative graph for MligTC455_25987

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.13 4.921 0.88827 1.00000
RegionR2 0.11 4.921 0.75466 1.00000
RegionR3 0.299 4.921 0.26612 0.81062
RegionR4 1.034 4.921 0.00206 0.01831
RegionR5 0.428 4.921 0.08180 0.26624
RegionR6 0.066 4.921 0.81497 1.00000
RegionR7 -0.755 4.921 0.06568 0.49266
RegionR8 -1.052 4.921 0.03758 0.38054

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.196 4.921 0.06648 0.74431
RegenerationR2 -0.357 4.921 0.19284 0.63696
RegenerationR3 -0.284 4.921 0.34962 0.77025
RegenerationR4 -0.303 4.921 0.33483 0.76834
RegenerationR5 0.406 4.921 0.13787 0.54854
RegenerationR6 -0.085 4.921 0.78865 0.97190
RegenerationBL 0.256 4.921 0.56035 0.91551
RegenerationTP 0.632 4.921 0.16067 0.58944


Genes with expression patterns similar to MligTC455_25987

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_25987 1137 23.68 Mlig455_045677, Mlig455_045688

Neo: -

Age: -

Region-enriched R4: 1.034/0.01831

AGPAT4 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_045677 {REF} {Length: 4133} {TRANSSPLICED} {Pfam: Acyltransferase C-terminus [PF16076.7, score=72.0]; Acyltransferase [PF01553.23, score=65.1]} {Human: ENSG00000026652, AGPAT4, 1-acylglycerol-3-phosphate O-acyltransferase 4, [RH, Score=281, Expect=2e-91]; ENSG00000160216, AGPAT3, 1-acylglycerol-3-phosphate O-acyltransferase 3, [RH, Score=270, Expect=3e-87]} {Mouse: ENSMUSG00000001211, Agpat3, 1-acylglycerol-3-phosphate O-acyltransferase 3, [RH, Score=273, Expect=1e-88]; ENSMUSG00000023827, Agpat4, 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta), [RH, Score=265, Expect=3e-85]} {Dmel: FBgn0036623, CG4729, [RH, Score=232, Expect=1e-72]} {Celegans: WBGene00044631, bus-18, [Score=106, Expect=2e-25]} {Smed: dd_Smed_v6_5643_0_1, dd_Smed_v6_5643_0_1, [RH, Score=228, Expect=5e-71]} {RNA1509_29014, RNA1509_52614} {RNA1310_17321.1, RNA1509_52614} {RNA1509_52614, RNA815_7698}

Mlig455_045688 {REF} {Length: 4198} {TRANSSPLICED} {Pfam: Acyltransferase C-terminus [PF16076.7, score=72.0]; Acyltransferase [PF01553.23, score=65.1]} {Human: ENSG00000026652, AGPAT4, 1-acylglycerol-3-phosphate O-acyltransferase 4, [RH, Score=281, Expect=2e-91]; ENSG00000160216, AGPAT3, 1-acylglycerol-3-phosphate O-acyltransferase 3, [RH, Score=270, Expect=3e-87]} {Mouse: ENSMUSG00000001211, Agpat3, 1-acylglycerol-3-phosphate O-acyltransferase 3, [RH, Score=273, Expect=1e-88]; ENSMUSG00000023827, Agpat4, 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta), [RH, Score=265, Expect=3e-85]} {Dmel: FBgn0036623, CG4729, [RH, Score=232, Expect=1e-72]} {Celegans: WBGene00044631, bus-18, [Score=106, Expect=2e-25]} {Smed: dd_Smed_v6_5643_0_1, dd_Smed_v6_5643_0_1, [RH, Score=228, Expect=5e-71]} {RNA1509_13486, RNA1509_29014, RNA1509_45027, RNA1509_50911} {RNA1310_17321.1, RNA1509_13486, RNA1509_29014, RNA1509_45027, RNA1509_50911} {RNA1509_13486, RNA1509_29014, RNA1509_45027, RNA1509_50911, RNA815_7698}
2. MligTC455_47781 1192 24.84 Mlig455_006493, Mlig455_006614

Neo: -

Age: -

1.863 - - - - 0.907 0.956

Mlig455_006493 {REF} {Length: 1635} {RNA1509_13310} {RNA1310_19450, RNA1509_13310} {RNA1509_13310, RNA815_7765}

Mlig455_006614 {REF} {Length: 1632} {TRANSSPLICED} {RNA1509_13310} {RNA1310_19450} {RNA815_7765}
3. MligTC455_29659 1489 31.02 Mlig455_013594

Neo: -

Age: logFC(26M/2M)=0.174

Regeneration-upregulated BL: 1.658

Regeneration-enriched BL: 1.658

UGP2 1.813 - - - 0.955 - 0.858 Mlig455_013594 {REF} {Length: 2365} {TRANSSPLICED} {Pfam: UTP--glucose-1-phosphate uridylyltransferase [PF01704.20, score=614.7]} {Human: ENSG00000169764, UGP2, UDP-glucose pyrophosphorylase 2, [RH, Score=634, Expect=0.0]} {Mouse: ENSMUSG00000001891, Ugp2, UDP-glucose pyrophosphorylase 2, [RH, Score=634, Expect=0.0]} {Dmel: FBgn0035978, UGP, [RH, Score=622, Expect=0.0]} {Celegans: WBGene00010665, K08E3.5, [RH, Score=621, Expect=0.0]} {Smed: dd_Smed_v6_3057_0_1, dd_Smed_v6_3057_0_1, [RH, Score=621, Expect=0.0]} {RNA1509_1617, RNA1509_16972, RNA1509_22084, RNA1509_34358, RNA1509_34975} {RNA1310_6161.1, RNA1509_16972, RNA1509_22084, RNA1509_34358, RNA1509_34975} {RNA1509_16972, RNA1509_22084, RNA1509_34358, RNA1509_34975, RNA815_2096.1}
4. MligTC455_25468 835 17.4 Mlig455_059894

Neo: Int S/G2/M

Age: Up-Down-Up

Region-enriched R4: 1.400/0.01794

PNKP 1.769 - - - - 0.815 0.954 Mlig455_059894 {REF} {Length: 3283} {Pfam: AAA domain [PF13671.8, score=41.5]; Chromatin associated protein KTI12 [PF08433.12, score=30.2]; Polynucleotide kinase 3 phosphatase [PF08645.13, score=24.0]; AAA ATPase domain [PF13191.8, score=23.8]} {Human: ENSG00000039650, PNKP, polynucleotide kinase 3'-phosphatase, [Score=144, Expect=2e-39]} {Mouse: ENSMUSG00000002963, Pnkp, polynucleotide kinase 3'- phosphatase, [Score=140, Expect=5e-38]} {Dmel: FBgn0037578, CG9601, [Score=132, Expect=7e-35]} {Celegans: WBGene00009010, F21D5.5, [Score=164, Expect=9e-48]} {Smed: dd_Smed_v6_1211_0_2, dd_Smed_v6_1211_0_2, [Score=146, Expect=9e-41]} {RNA1509_29141, RNA1509_38859} {RNA1310_5154.1, RNA1509_29141} {RNA1509_29141, RNA815_12031}
5. MligTC455_34976 1568 32.66 Mlig455_037934

Neo: -

Age: -

Region-enriched R5: 1.150/0.00097

EPN2 1.755 - - - - 0.799 0.956 Mlig455_037934 {REF} {Length: 4839} {TRANSSPLICED} {Pfam: ENTH domain [PF01417.22, score=158.4]; ANTH domain [PF07651.18, score=28.2]; VHS domain [PF00790.21, score=23.9]} {Human: ENSG00000072134, EPN2, epsin 2, [Score=309, Expect=5e-97]; ENSG00000063245, EPN1, epsin 1, [Score=304, Expect=5e-95]} {Mouse: ENSMUSG00000035203, Epn1, epsin 1, [Score=311, Expect=7e-98]} {Dmel: FBgn0028582, lqf, liquid facets, [RH, Score=283, Expect=5e-85]} {Celegans: WBGene00001329, epn-1, EPsiN (Endocytic protein) homolog, [Score=265, Expect=4e-82]} {Smed: dd_Smed_v6_4779_0_1, dd_Smed_v6_4779_0_1, [RH, Score=280, Expect=3e-86]} {RNA1509_10151} {RNA1310_15538, RNA1509_10151} {RNA1509_10151, RNA815_19613}
6. MligTC455_15616 879 18.31 Mlig455_001922

Neo: -

Age: -

LEPROTL1 1.746 - - - 0.784 - 0.962 Mlig455_001922 {REF} {Length: 3020} {TRANSSPLICED} {Pfam: Vacuolar protein sorting 55 [PF04133.16, score=123.9]} {Human: ENSG00000104660, LEPROTL1, leptin receptor overlapping transcript like 1, [RH, Score=151, Expect=8e-48]; ENSG00000213625, LEPROT, leptin receptor overlapping transcript, [RH, Score=147, Expect=3e-46]} {Mouse: ENSMUSG00000035212, Leprot, leptin receptor overlapping transcript, [RH, Score=153, Expect=7e-49]; ENSMUSG00000031513, Leprotl1, leptin receptor overlapping transcript-like 1, [RH, Score=151, Expect=7e-48]} {Dmel: FBgn0050423, CG30423, [RH, Score=82.0, Expect=8e-21]} {Celegans: WBGene00016244, C30B5.2, Vacuolar protein sorting-associated protein 55 homolog, [RH, Score=122, Expect=1e-36]} {Smed: dd_Smed_v6_7026_0_1, dd_Smed_v6_7026_0_1, [RH, Score=144, Expect=2e-45]} {RNA1509_43244} {RNA1310_15087.1} {RNA815_20068}
7. MligTC455_35099 2100 43.74 Mlig455_018503

Neo: -

Age: Down-Down-Up

FKBP2 1.742 - - - 0.780 - 0.962 Mlig455_018503 {REF} {Length: 1379} {TRANSSPLICED} {Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase [PF00254.30, score=117.7]} {Human: ENSG00000173486, FKBP2, FK506 binding protein 2, [RH, Score=165, Expect=1e-52]} {Mouse: ENSMUSG00000056629, Fkbp2, FK506 binding protein 2, [RH, Score=166, Expect=3e-53]} {Dmel: FBgn0010470, Fkbp14, FK506-binding protein 14, [RH, Score=137, Expect=4e-41]} {Celegans: WBGene00001426, fkb-1, Peptidylprolyl isomerase, [RH, Score=163, Expect=2e-52]} {Smed: dd_Smed_v6_1536_0_1, dd_Smed_v6_1536_0_1, [RH, Score=173, Expect=2e-56]} {RNA1509_27564} {RNA1310_35669.1, RNA1509_27564} {RNA1509_27564, RNA815_16576}
8. MligTC455_15615 833 17.34 Mlig455_001850

Neo: -

Age: Up-Down-Up

LEPROTL1 1.734 - - - 0.766 - 0.968 Mlig455_001850 {REF} {Length: 1308} {TRANSSPLICED} {Pfam: Vacuolar protein sorting 55 [PF04133.16, score=123.9]} {Human: ENSG00000104660, LEPROTL1, leptin receptor overlapping transcript like 1, [RH, Score=151, Expect=8e-48]; ENSG00000213625, LEPROT, leptin receptor overlapping transcript, [RH, Score=147, Expect=3e-46]} {Mouse: ENSMUSG00000035212, Leprot, leptin receptor overlapping transcript, [RH, Score=153, Expect=7e-49]; ENSMUSG00000031513, Leprotl1, leptin receptor overlapping transcript-like 1, [RH, Score=151, Expect=7e-48]} {Dmel: FBgn0050423, CG30423, [RH, Score=82.0, Expect=8e-21]} {Celegans: WBGene00016244, C30B5.2, Vacuolar protein sorting-associated protein 55 homolog, [RH, Score=122, Expect=1e-36]} {Smed: dd_Smed_v6_7026_0_1, dd_Smed_v6_7026_0_1, [RH, Score=144, Expect=2e-45]} {RNA1509_43244} {RNA1310_15087.2} {RNA815_20068}
9. MligTC455_50675 648 13.5 Mlig455_017899

Neo: -

Age: -

1.694 - - - - 0.738 0.956 Mlig455_017899 {REF} {Length: 2179} {RNA1509_14147, RNA1509_51574, RNA1509_53971} {RNA1310_35088, RNA1509_14147, RNA1509_51574, RNA1509_53971} {RNA1509_14147, RNA1509_51574, RNA1509_53971, RNA815_14923}
10. MligTC455_20308 614 12.79 Mlig455_022336

Neo: -

Age: -

PLPP1 1.688 - - - 0.737 - 0.951 Mlig455_022336 {REF} {Length: 2324} {TRANSSPLICED} {Pfam: PAP2 superfamily [PF01569.23, score=92.7]} {Human: ENSG00000067113, PLPP1, phospholipid phosphatase 1, [Score=131, Expect=2e-35]; ENSG00000141934, PLPP2, phospholipid phosphatase 2, [Score=128, Expect=3e-34]} {Mouse: ENSMUSG00000021759, Plpp1, phospholipid phosphatase 1, [RH, Score=134, Expect=8e-37]} {Dmel: FBgn0037166, CG11426, [RH, Score=137, Expect=2e-37]} {Celegans: WBGene00018756, F53C3.13, [Score=125, Expect=3e-33]} {Smed: dd_Smed_v6_1907_0_1, dd_Smed_v6_1907_0_1, [Score=120, Expect=1e-31]} {RNA1509_45886, RNA1509_5086} {RNA1310_10493.1, RNA1509_45886, RNA1509_5086} {RNA1509_45886, RNA1509_5086, RNA815_8680.2}
11. MligTC455_30041 2719 56.65 Mlig455_004160, Mlig455_004186

Neo: -

Age: logFC(26M/2M)=0.572

Region-enriched R4: 1.550/0.00000

FAR1 1.67 - - - - 0.716 0.954

Mlig455_004160 {REF} {Length: 2497} {TRANSSPLICED} {Pfam: Male sterility protein [PF07993.14, score=246.1]; Male sterility protein [PF03015.21, score=96.6]} {Human: ENSG00000197601, FAR1, fatty acyl-CoA reductase 1, [RH, Score=466, Expect=7e-160]} {Mouse: ENSMUSG00000030759, Far1, fatty acyl CoA reductase 1, [RH, Score=467, Expect=1e-160]} {Dmel: FBgn0034145, CG5065, [RH, Score=428, Expect=7e-144]} {Celegans: WBGene00022200, fard-1, Fatty acyl-CoA reductase, [RH, Score=406, Expect=1e-136]} {Smed: dd_Smed_v6_7206_0_1, dd_Smed_v6_7206_0_1, [RH, Score=375, Expect=1e-124]} {RNA1509_13010} {RNA1310_6154} {RNA815_2225}

Mlig455_004186 {REF} {Length: 2492} {TRANSSPLICED} {Pfam: Male sterility protein [PF07993.14, score=243.0]; Male sterility protein [PF03015.21, score=96.5]; NAD dependent epimerase/dehydratase family [PF01370.23, score=18.7]} {Human: ENSG00000197601, FAR1, fatty acyl-CoA reductase 1, [RH, Score=464, Expect=5e-159]} {Mouse: ENSMUSG00000030759, Far1, fatty acyl CoA reductase 1, [RH, Score=466, Expect=6e-160]} {Dmel: FBgn0034145, CG5065, [RH, Score=424, Expect=2e-142]} {Celegans: WBGene00022200, fard-1, Fatty acyl-CoA reductase, [RH, Score=404, Expect=7e-136]} {Smed: dd_Smed_v6_7206_0_1, dd_Smed_v6_7206_0_1, [RH, Score=374, Expect=5e-124]} {RNA1509_13010, RNA1509_2627} {RNA1310_6154, RNA1509_13010, RNA1509_2627} {RNA1509_13010, RNA1509_2627, RNA815_2225}
12. MligTC455_14911 498 10.38 Mlig455_024924

Neo: -

Age: -

0.988 - - - - - 0.988 Mlig455_024924 {REF} {Length: 1825} {TRANSSPLICED} {RNA1509_24815, RNA1509_41866} {RNA1310_11114, RNA1509_24815, RNA1509_41866} {RNA1509_24815, RNA1509_41866, RNA815_15710}
13. MligTC455_14912 498 10.38 Mlig455_024956

Neo: -

Age: -

0.974 - - - - - 0.974 Mlig455_024956 {REF} {Length: 1758} {TRANSSPLICED} {RNA1509_41866} {RNA1310_11114} {RNA815_15710}
14. MligTC455_25265 1284 26.74 Mlig455_058038

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.082

Region-enriched R4: 1.930/0.00051
Region-enriched R5: 1.049/0.03707

VPS37B 0.973 - - - - - 0.973 Mlig455_058038 {REF} {Length: 1303} {TRANSSPLICED} {Pfam: Modifier of rudimentary (Mod(r)) protein [PF07200.15, score=81.6]} {Human: ENSG00000139722, VPS37B, VPS37B, ESCRT-I subunit, [RH, Score=79.3, Expect=6e-17]} {Mouse: ENSMUSG00000048832, Vps37c, vacuolar protein sorting 37C, [RH, Score=67.4, Expect=1e-12]; ENSMUSG00000066278, Vps37b, vacuolar protein sorting 37B, [RH, Score=65.9, Expect=2e-12]} {Dmel: FBgn0037299, Vps37B, Vacuolar protein sorting 37B, [Score=55.5, Expect=4e-09]} {RNA1509_4762} {RNA1310_1499.1} {RNA815_9957}
15. MligTC455_43022 1772 36.91 Mlig455_006338, Mlig455_061233

Neo: -

Age: -

Region-enriched R5: 1.963/0.00031
Region-enriched R4: 1.635/0.03853

RAB35 0.971 - - - - - 0.971

Mlig455_006338 {REF} {Length: 3641} {Pfam: Ras family [PF00071.24, score=201.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=120.4]; ADP-ribosylation factor family [PF00025.23, score=55.1]; 50S ribosome-binding GTPase [PF01926.25, score=27.8]; RsgA GTPase [PF03193.18, score=23.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=22.5]; Gtr1/RagA G protein conserved region [PF04670.14, score=20.3]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [RH, Score=249, Expect=2e-84]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [RH, Score=249, Expect=2e-84]} {Dmel: FBgn0031090, Rab35, [RH, Score=236, Expect=3e-79]} {Celegans: WBGene00004284, rab-35, RAB family, [RH, Score=233, Expect=6e-78]} {Smed: dd_Smed_v6_854_0_8, dd_Smed_v6_854_0_8, [Score=211, Expect=1e-69]} {RNA1509_17024, RNA1509_19785} {RNA1310_25273, RNA1509_17024} {RNA1509_17024, RNA815_11011.1}

Mlig455_061233 {REF} {Length: 3852} {Pfam: Ras family [PF00071.24, score=187.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=106.1]; ADP-ribosylation factor family [PF00025.23, score=47.7]; Elongation factor Tu GTP binding domain [PF00009.29, score=21.9]; 50S ribosome-binding GTPase [PF01926.25, score=20.1]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [Score=222, Expect=1e-73]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [Score=222, Expect=7e-74]} {Dmel: FBgn0031090, Rab35, [RH, Score=210, Expect=2e-69]} {Celegans: WBGene00004284, rab-35, RAB family, [Score=203, Expect=1e-66]} {Smed: dd_Smed_v6_488_0_1, dd_Smed_v6_488_0_1, [Score=188, Expect=6e-61]} {RNA1509_19785} {RNA1310_25273} {RNA815_11011.1}
16. MligTC455_46508 553 11.53 Mlig455_039158

Neo: -

Age: -

Region-enriched R4: 3.087/0.02676

0.969 - - - - - 0.969 Mlig455_039158 {REF} {Length: 2537} {Pfam: Lysosomal transcription factor, NCU-G1 [PF15065.8, score=241.7]} {Smed: dd_Smed_v6_2685_0_1, dd_Smed_v6_2685_0_1, [RH, Score=139, Expect=1e-36]} {RNA1509_23056, RNA1509_24004, RNA1509_36817, RNA1509_7566} {RNA1310_18836, RNA1509_23056, RNA1509_24004, RNA1509_36817} {RNA1509_23056, RNA1509_24004, RNA1509_36817, RNA815_9023}
17. MligTC455_43021 837 17.43 Mlig455_006334

Neo: -

Age: -

Region-enriched R4: 1.971/0.00562
Region-enriched R5: 1.754/0.00033

RAB35 0.967 - - - - - 0.967 Mlig455_006334 {REF} {Length: 2734} {Pfam: Ras family [PF00071.24, score=200.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=120.5]; ADP-ribosylation factor family [PF00025.23, score=55.4]; 50S ribosome-binding GTPase [PF01926.25, score=27.8]; RsgA GTPase [PF03193.18, score=23.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=22.4]; Gtr1/RagA G protein conserved region [PF04670.14, score=20.3]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [RH, Score=249, Expect=2e-84]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [RH, Score=249, Expect=2e-84]} {Dmel: FBgn0031090, Rab35, [RH, Score=236, Expect=3e-79]} {Celegans: WBGene00004284, rab-35, RAB family, [RH, Score=232, Expect=9e-78]} {Smed: dd_Smed_v6_488_0_1, dd_Smed_v6_488_0_1, [Score=209, Expect=6e-69]} {RNA1509_19785, RNA1509_46148} {RNA1310_25273, RNA1509_46148} {RNA1509_46148, RNA815_11011.1}
18. MligTC455_43045 816 16.99 Mlig455_013899

Neo: -

Age: -

FZD1 0.967 - - - - - 0.967 Mlig455_013899 {REF} {Length: 4439} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=357.3]; Fz domain [PF01392.24, score=91.8]} {Human: ENSG00000157240, FZD1, frizzled class receptor 1, [Score=394, Expect=2e-128]} {Mouse: ENSMUSG00000044674, Fzd1, frizzled class receptor 1, [Score=389, Expect=1e-126]; ENSMUSG00000050288, Fzd2, frizzled class receptor 2, [Score=372, Expect=6e-121]} {Dmel: FBgn0001085, fz, frizzled, [Score=383, Expect=4e-125]} {Celegans: WBGene00003397, mom-5, [Score=322, Expect=4e-102]} {Smed: dd_Smed_v6_6353_0_1, dd_Smed_v6_6353_0_1, [RH, Score=389, Expect=3e-127]} {RNA1509_57703} {RNA1310_3311, RNA1509_57703} {RNA1509_57703, RNA815_1101.1}
19. MligTC455_45094 977 20.35 Mlig455_054603

Neo: -

Age: Down-Down-Up

0.967 - - - - - 0.967 Mlig455_054603 {REF} {Length: 996} {TRANSSPLICED} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=41.3]; Leucine rich repeat [PF13855.8, score=35.7]; Leucine-rich repeat [PF14580.8, score=32.6]; Leucine Rich repeat [PF13516.8, score=19.9]} {Dmel: FBgn0051076, CG31076, [RH, Score=60.8, Expect=9e-12]} {Celegans: WBGene00020574, T19D7.6, [RH, Score=48.1, Expect=3e-07]} {Smed: dd_Smed_v6_2559_0_1, dd_Smed_v6_2559_0_1, [RH, Score=86.7, Expect=8e-22]} {RNA1509_13107, RNA1509_29185} {RNA1310_35783, RNA1509_13107} {RNA1509_13107, RNA815_477.1}
20. MligTC455_25266 1293 26.93 Mlig455_058082

Neo: -

Age: logFC(26M/2M)=0.494

Region-enriched R4: 1.940/0.00065

VPS37B 0.966 - - - - - 0.966 Mlig455_058082 {REF} {Length: 1292} {TRANSSPLICED} {Pfam: Modifier of rudimentary (Mod(r)) protein [PF07200.15, score=81.6]} {Human: ENSG00000139722, VPS37B, VPS37B, ESCRT-I subunit, [RH, Score=78.6, Expect=1e-16]} {Mouse: ENSMUSG00000048832, Vps37c, vacuolar protein sorting 37C, [RH, Score=66.2, Expect=3e-12]; ENSMUSG00000066278, Vps37b, vacuolar protein sorting 37B, [RH, Score=65.5, Expect=4e-12]} {Dmel: FBgn0037299, Vps37B, Vacuolar protein sorting 37B, [Score=55.1, Expect=6e-09]} {RNA1509_20495, RNA1509_35491, RNA1509_40503, RNA1509_4762} {RNA1310_1499.1, RNA1509_20495, RNA1509_35491, RNA1509_40503, RNA1509_4762} {RNA1509_20495, RNA1509_35491, RNA1509_40503, RNA1509_4762, RNA815_9957}
21. MligTC455_20593 717 14.93 Mlig455_013609

Neo: -

Age: -

TVP23B 0.962 - - - - - 0.962 Mlig455_013609 {REF} {Length: 2266} {TRANSSPLICED} {Pfam: Eukaryotic protein of unknown function (DUF846) [PF05832.14, score=165.1]} {Human: ENSG00000171928, TVP23B, trans-golgi network vesicle protein 23 homolog B, [RH, Score=184, Expect=3e-58]; ENSG00000175106, TVP23C, trans-golgi network vesicle protein 23 homolog C, [RH, Score=184, Expect=6e-58]} {Mouse: ENSMUSG00000014177, Tvp23b, trans-golgi network vesicle protein 23B, [RH, Score=186, Expect=7e-59]} {Dmel: FBgn0035944, CG5021, [RH, Score=174, Expect=4e-54]} {Celegans: WBGene00016400, C34D4.4, Uncharacterized Golgi apparatus membrane protein-like protein C34D4.4, [RH, Score=127, Expect=2e-36]} {Smed: dd_Smed_v6_3386_0_1, dd_Smed_v6_3386_0_1, [RH, Score=160, Expect=2e-49]} {RNA1509_36306, RNA1509_47142, RNA1509_52712, RNA1509_56436, RNA1509_7370} {RNA1310_32400, RNA1509_36306, RNA1509_47142, RNA1509_52712, RNA1509_56436, RNA1509_7370} {RNA1509_36306, RNA1509_47142, RNA1509_52712, RNA1509_56436, RNA1509_7370, RNA815_15068}
22. MligTC455_44537 170 3.54 Mlig455_042390

Neo: -

Age: -

PRDM10 0.959 - - - - - 0.959 Mlig455_042390 {REF} {Length: 5376} {TRANSSPLICED} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=54.6]; C2H2-type zinc finger [PF13894.8, score=52.9]; C2H2 type zinc-finger (2 copies) [PF12756.9, score=25.9]; Zinc-finger of C2H2 type [PF12874.9, score=23.3]} {Human: ENSG00000170325, PRDM10, PR/SET domain 10, [RH, Score=149, Expect=2e-36]} {Mouse: ENSMUSG00000042496, Prdm10, PR domain containing 10, [RH, Score=149, Expect=3e-36]} {Dmel: FBgn0030314, CG11696, [Score=56.6, Expect=8e-08]} {RNA1509_23473} {RNA1310_4659, RNA1509_23473} {RNA1509_23473, RNA815_26860}
23. MligTC455_07596 993 20.7 Mlig455_017772, Mlig455_017779, Mlig455_069259

Neo: -

Age: -

PLPP5 0.958 - - 0.958 - - -

Mlig455_017772 {REF} {Length: 573} {NoTransDecoderORF} {RNA1509_58941} {RNA1310_48208} {RNA815_28409}

Mlig455_017779 {REF} {Length: 2191} {TRANSSPLICED} {Pfam: PAP2 superfamily [PF01569.23, score=100.1]} {Human: ENSG00000147535, PLPP5, phospholipid phosphatase 5, [Score=157, Expect=9e-46]; ENSG00000203805, PLPP4, phospholipid phosphatase 4, [Score=151, Expect=3e-43]} {Mouse: ENSMUSG00000031570, Plpp5, phospholipid phosphatase 5, [Score=159, Expect=6e-47]} {Dmel: FBgn0037341, CG12746, [Score=128, Expect=6e-34]} {Celegans: WBGene00020895, T28D9.3, [Score=60.5, Expect=3e-10]} {Smed: dd_Smed_v6_3897_0_1, dd_Smed_v6_3897_0_1, [Score=157, Expect=4e-46]} {RNA1509_27099, RNA1509_58941} {RNA1310_28641.1, RNA1509_27099, RNA1509_58941} {RNA1509_27099, RNA1509_58941, RNA815_13272}

Mlig455_069259 {REF} {Length: 2642} {TRANSSPLICED} {Pfam: PAP2 superfamily [PF01569.23, score=101.6]} {Human: ENSG00000147535, PLPP5, phospholipid phosphatase 5, [Score=159, Expect=2e-46]; ENSG00000203805, PLPP4, phospholipid phosphatase 4, [Score=155, Expect=1e-44]} {Mouse: ENSMUSG00000031570, Plpp5, phospholipid phosphatase 5, [Score=160, Expect=4e-47]; ENSMUSG00000070366, Plpp4, phospholipid phosphatase 4, [Score=154, Expect=7e-45]} {Dmel: FBgn0037341, CG12746, [Score=129, Expect=2e-34]} {Celegans: WBGene00020895, T28D9.3, [Score=59.7, Expect=6e-10]} {Smed: dd_Smed_v6_3897_0_1, dd_Smed_v6_3897_0_1, [Score=155, Expect=2e-45]} {RNA1509_27099} {RNA1310_28641.2} {RNA815_13272}
24. MligTC455_39377 2992 62.33 Mlig455_046114, Mlig455_046209

Neo: -

Age: logFC(26M/2M)=0.255

FUCA2 0.956 - - - - - 0.956

Mlig455_046114 {REF} {Length: 2446} {TRANSSPLICED} {Pfam: Alpha-L-fucosidase [PF01120.19, score=415.7]; Alpha-L-fucosidase C-terminal domain [PF16757.7, score=71.4]} {Human: ENSG00000001036, FUCA2, alpha-L-fucosidase 2, [RH, Score=542, Expect=0.0]; ENSG00000179163, FUCA1, alpha-L-fucosidase 1, [RH, Score=520, Expect=0.0]} {Mouse: ENSMUSG00000019810, Fuca2, fucosidase, alpha-L- 2, plasma, [RH, Score=535, Expect=0.0]; ENSMUSG00000028673, Fuca1, fucosidase, alpha-L- 1, tissue, [RH, Score=517, Expect=0.0]} {Dmel: FBgn0285958, Fuca, alpha-L-fucosidase, [RH, Score=465, Expect=3e-161]} {Celegans: WBGene00012225, W03G11.3, Putative alpha-L-fucosidase, [RH, Score=424, Expect=4e-145]} {Smed: dd_Smed_v6_8422_0_1, dd_Smed_v6_8422_0_1, [RH, Score=541, Expect=0.0]} {RNA1509_6158} {RNA1310_6463} {RNA815_1561}

Mlig455_046209 {REF} {Length: 3321} {TRANSSPLICED} {Pfam: Alpha-L-fucosidase [PF01120.19, score=417.3]; Alpha-L-fucosidase C-terminal domain [PF16757.7, score=71.3]} {Human: ENSG00000001036, FUCA2, alpha-L-fucosidase 2, [RH, Score=537, Expect=0.0]; ENSG00000179163, FUCA1, alpha-L-fucosidase 1, [RH, Score=518, Expect=0.0]} {Mouse: ENSMUSG00000019810, Fuca2, fucosidase, alpha-L- 2, plasma, [RH, Score=530, Expect=0.0]; ENSMUSG00000028673, Fuca1, fucosidase, alpha-L- 1, tissue, [RH, Score=516, Expect=0.0]} {Dmel: FBgn0285958, Fuca, alpha-L-fucosidase, [RH, Score=466, Expect=1e-161]} {Celegans: WBGene00012225, W03G11.3, Putative alpha-L-fucosidase, [RH, Score=421, Expect=7e-144]} {Smed: dd_Smed_v6_8422_0_1, dd_Smed_v6_8422_0_1, [RH, Score=538, Expect=0.0]} {RNA1509_12330, RNA1509_16238, RNA1509_6158} {RNA1310_9914.1, RNA1509_12330, RNA1509_16238, RNA1509_6158} {RNA1509_12330, RNA1509_16238, RNA1509_6158, RNA815_1561}
25. MligTC455_30647 304 6.33 Mlig455_025006

Neo: -

Age: Up-Down-Down

SACS 0.955 - - 0.955 - - - Mlig455_025006 {REF} {Length: 13439} {Pfam: HEPN domain [PF05168.16, score=55.3]} {Human: ENSG00000151835, SACS, sacsin molecular chaperone, [Score=619, Expect=5e-178]} {Mouse: ENSMUSG00000048279, Sacs, sacsin, [RH, Score=608, Expect=1e-174]} {RNA1509_39632, RNA1509_44660, RNA1509_56235} {RNA1310_2346.1, RNA1509_39632, RNA1509_44660} {RNA1509_39632, RNA1509_44660, RNA815_63.1}
26. MligTC455_49770 476 9.92 Mlig455_020682, Mlig455_020688, Mlig455_020755

Neo: -

Age: logFC(26M/2M)=-0.284

Region-enriched R2: 2.437/0.04447

TCTN2 0.955 - - - 0.955 - -

Mlig455_020682 {REF} {Length: 3354} {Pfam: Protein of unknown function (DUF1619) [PF07773.13, score=128.7]} {Human: ENSG00000168778, TCTN2, tectonic family member 2, [RH, Score=120, Expect=5e-28]} {Mouse: ENSMUSG00000038593, Tctn1, tectonic family member 1, [Score=86.7, Expect=2e-17]} {Smed: dd_Smed_v6_11318_0_1, dd_Smed_v6_11318_0_1, [RH, Score=144, Expect=6e-36]} {RNA1509_12497} {RNA1310_8819, RNA1509_12497} {RNA1509_12497, RNA815_5215}

Mlig455_020688 {REF} {Length: 3253} {Pfam: Protein of unknown function (DUF1619) [PF07773.13, score=128.9]} {Human: ENSG00000168778, TCTN2, tectonic family member 2, [RH, Score=121, Expect=3e-28]} {Mouse: ENSMUSG00000038593, Tctn1, tectonic family member 1, [Score=85.5, Expect=5e-17]} {Smed: dd_Smed_v6_11318_0_1, dd_Smed_v6_11318_0_1, [RH, Score=146, Expect=2e-36]} {RNA1509_12497} {RNA1310_8819} {RNA815_5215}

Mlig455_020755 {REF} {Length: 1235} {Pfam: Protein of unknown function (DUF1619) [PF07773.13, score=50.9]} {RNA1509_12497} {RNA1310_10004} {RNA815_5215}
27. MligTC455_53919 394 8.2 Mlig455_022726

Neo: -

Age: -

RPGR 0.95 - - 0.950 - - - Mlig455_022726 {REF} {Length: 4679} {Pfam: Regulator of chromosome condensation (RCC1) repeat [PF00415.20, score=168.1]; Regulator of chromosome condensation (RCC1) repeat [PF13540.8, score=127.2]} {Human: ENSG00000156313, RPGR, retinitis pigmentosa GTPase regulator, [Score=218, Expect=7e-58]} {Mouse: ENSMUSG00000031174, Rpgr, retinitis pigmentosa GTPase regulator, [Score=209, Expect=2e-55]} {Dmel: FBgn0035207, Sherpa, SUMO-related HECT domain and RCC repeat protein for Toll pathway activation, [Score=130, Expect=2e-30]} {Celegans: WBGene00021685, herc-1, HECT and RCC domain E3 ubiquitin ligase, [Score=99.8, Expect=5e-21]} {Smed: dd_Smed_v6_2716_1_1, dd_Smed_v6_2716_1_1, [RH, Score=217, Expect=3e-60]} {RNA1509_21041} {RNA1310_3558.1, RNA1509_21041} {RNA1509_21041, RNA815_17415}

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