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Results for MligTC455_27318

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_27318 28966 603.46 Mlig455_003989

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.989

CAV1 Mlig455_003989 {REF} {Length: 1127} {TRANSSPLICED} {Pfam: Caveolin [PF01146.19, score=129.4]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=108, Expect=1e-30]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=108, Expect=8e-31]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=85.1, Expect=5e-21]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=151, Expect=2e-48]} {RNA1509_21685, RNA1509_50039, RNA1509_917} {RNA1310_44240, RNA1509_50039, RNA1509_917} {RNA1509_50039, RNA1509_917, RNA815_15431.2}

Cumulative graph for MligTC455_27318

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.162 9.292 0.00160 0.13087
RegionR2 0.578 9.292 0.04336 0.24447
RegionR3 0.602 9.292 0.01703 0.21402
RegionR4 0.351 9.292 0.21964 0.50841
RegionR5 -0.194 9.292 0.45714 0.81941
RegionR6 -0.08 9.292 0.76109 1.00000
RegionR7 0.132 9.292 0.60198 1.00000
RegionR8 -0.228 9.292 0.40391 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.11 9.292 0.79928 1.00000
RegenerationR2 -0.209 9.292 0.53469 0.88621
RegenerationR3 -0.632 9.292 0.06156 0.42028
RegenerationR4 -0.581 9.292 0.09307 0.47575
RegenerationR5 -0.407 9.292 0.23051 0.66451
RegenerationR6 -0.645 9.292 0.05755 0.30094
RegenerationBL -0.856 9.292 0.00417 0.05836
RegenerationTP -0.672 9.292 0.03218 0.30128


Genes with expression patterns similar to MligTC455_27318

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_27318 28966 603.46 Mlig455_003989

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.989

CAV1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_003989 {REF} {Length: 1127} {TRANSSPLICED} {Pfam: Caveolin [PF01146.19, score=129.4]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=108, Expect=1e-30]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=108, Expect=8e-31]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=85.1, Expect=5e-21]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=151, Expect=2e-48]} {RNA1509_21685, RNA1509_50039, RNA1509_917} {RNA1310_44240, RNA1509_50039, RNA1509_917} {RNA1509_50039, RNA1509_917, RNA815_15431.2}
2. MligTC455_27319 22644 471.74 Mlig455_004072

Neo: -

Age: logFC(26M/2M)=-0.336

CAV1 5.8 0.964 0.967 0.958 0.978 0.959 0.974 Mlig455_004072 {REF} {Length: 1883} {Pfam: Caveolin [PF01146.19, score=129.4]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=108, Expect=1e-30]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=108, Expect=8e-31]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=85.1, Expect=5e-21]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=151, Expect=2e-48]} {RNA1509_13789, RNA1509_19184, RNA1509_2112, RNA1509_21685, RNA1509_25625, RNA1509_25666} {RNA1310_44240, RNA1509_13789, RNA1509_19184, RNA1509_2112, RNA1509_21685, RNA1509_25625, RNA1509_25666} {RNA1509_13789, RNA1509_19184, RNA1509_2112, RNA1509_21685, RNA1509_25625, RNA1509_25666, RNA815_15431.2}
3. MligTC455_27317 21175 441.14 Mlig455_003976

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.379

CAV1 5.729 0.966 0.968 0.943 0.946 0.942 0.964 Mlig455_003976 {REF} {Length: 1759} {TRANSSPLICED} {Pfam: Caveolin [PF01146.19, score=129.4]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=108, Expect=1e-30]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=108, Expect=8e-31]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=85.1, Expect=5e-21]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=151, Expect=2e-48]} {RNA1509_21685} {RNA1310_44240} {RNA815_15431.2}
4. MligTC455_36256 29037 604.93 Mlig455_011274

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=3.595

Region-specific R2: 2.067

Region-enriched R2: 1.321/0.02321

5.391 0.910 0.943 0.936 0.733 0.915 0.954 Mlig455_011274 {REF} {Length: 1147} {RNA1509_11253} {RNA1310_37614} {RNA815_20484.2}
5. MligTC455_36257 29266 609.7 Mlig455_011370

Neo: -

Age: logFC(26M/2M)=-0.477

Region-specific R2: 2.059

Region-enriched R2: 1.316/0.02389

5.387 0.909 0.944 0.936 0.729 0.915 0.954 Mlig455_011370 {REF} {Length: 1231} {RNA1509_11253, RNA1509_208, RNA1509_49400, RNA1509_498} {RNA1310_37614, RNA1509_11253, RNA1509_208, RNA1509_49400, RNA1509_498} {RNA1509_11253, RNA1509_208, RNA1509_49400, RNA1509_498, RNA815_20484.2}
6. MligTC455_40554 2265 47.18 Mlig455_028418

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.536

Region-specific R2: 2.078

Region-enriched R2: 1.385/0.00761

Regeneration-depleted BL: -2.309
Regeneration-depleted R6: -1.979

CALML3 5.327 0.888 0.907 0.828 0.980 0.889 0.835 Mlig455_028418 {REF} {Length: 966} {Pfam: EF-hand domain pair [PF13499.8, score=107.0]; EF-hand domain [PF13405.8, score=88.7]; EF hand [PF00036.34, score=85.4]; EF-hand domain pair [PF13833.8, score=63.1]; EF hand [PF13202.8, score=46.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=27.9]; EF-hand domain [PF14658.8, score=27.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.9]; Ca2+ insensitive EF hand [PF08726.12, score=22.1]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=94.0, Expect=1e-24]; ENSG00000143933, CALM2, calmodulin 2, [Score=93.2, Expect=3e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=93.2, Expect=3e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=93.2, Expect=3e-24]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=94.7, Expect=4e-25]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=93.2, Expect=2e-24]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=93.2, Expect=2e-24]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=93.2, Expect=2e-24]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=90.5, Expect=2e-23]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=89.7, Expect=2e-23]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=89.7, Expect=2e-23]} {RNA1509_2799, RNA1509_7376} {RNA1310_30171, RNA1509_2799} {RNA1509_2799, RNA815_22911}
7. MligTC455_40555 4294 89.47 Mlig455_028405, Mlig455_028439

Neo: -

Age: logFC(26M/2M)=0.704

Region-specific R2: 2.095

Region-enriched R2: 1.320/0.00861

Regeneration-depleted BL: -2.352
Regeneration-depleted R6: -2.070
Regeneration-depleted R3: -1.661

CALML3 5.314 0.887 0.903 0.823 0.976 0.890 0.835

Mlig455_028405 {REF} {Length: 1039} {Pfam: EF-hand domain pair [PF13499.8, score=107.0]; EF-hand domain [PF13405.8, score=88.7]; EF hand [PF00036.34, score=85.4]; EF-hand domain pair [PF13833.8, score=63.1]; EF hand [PF13202.8, score=46.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=27.9]; EF-hand domain [PF14658.8, score=27.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.9]; Ca2+ insensitive EF hand [PF08726.12, score=22.1]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=94.0, Expect=1e-24]; ENSG00000143933, CALM2, calmodulin 2, [Score=93.2, Expect=3e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=93.2, Expect=3e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=93.2, Expect=3e-24]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=94.7, Expect=4e-25]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=93.2, Expect=2e-24]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=93.2, Expect=2e-24]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=93.2, Expect=2e-24]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=90.5, Expect=2e-23]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=89.7, Expect=2e-23]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=89.7, Expect=2e-23]} {RNA1509_7376} {RNA1310_30171} {RNA815_22911}

Mlig455_028439 {REF} {Length: 1042} {Pfam: EF-hand domain pair [PF13499.8, score=107.0]; EF-hand domain [PF13405.8, score=88.7]; EF hand [PF00036.34, score=85.4]; EF-hand domain pair [PF13833.8, score=63.1]; EF hand [PF13202.8, score=46.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=27.9]; EF-hand domain [PF14658.8, score=27.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.9]; Ca2+ insensitive EF hand [PF08726.12, score=22.1]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=94.0, Expect=1e-24]; ENSG00000143933, CALM2, calmodulin 2, [Score=93.2, Expect=3e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=93.2, Expect=3e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=93.2, Expect=3e-24]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=94.7, Expect=4e-25]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=93.2, Expect=2e-24]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=93.2, Expect=2e-24]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=93.2, Expect=2e-24]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=90.5, Expect=2e-23]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=89.7, Expect=2e-23]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=89.7, Expect=2e-23]} {RNA1509_7376} {RNA1310_30171, RNA1509_7376} {RNA1509_7376, RNA815_22911}
8. MligTC455_30023 17914 373.2 Mlig455_004073

Neo: -

Age: logFC(26M/2M)=-0.534

Region-enriched R2: 1.038/0.04465

CAV1 5.226 0.800 0.914 0.799 0.961 0.900 0.852 Mlig455_004073 {REF} {Length: 996} {Pfam: Caveolin [PF01146.19, score=125.9]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=106, Expect=6e-30]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=104, Expect=3e-29]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=84.3, Expect=7e-21]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=150, Expect=6e-48]} {RNA1509_12190, RNA1509_37804, RNA1509_58757} {RNA1310_35724, RNA1509_12190, RNA1509_37804, RNA1509_58757} {RNA1509_12190, RNA1509_37804, RNA1509_58757, RNA815_6720.1}
9. MligTC455_44958 13148 273.91 Mlig455_031389

Neo: -

Age: Down-Down-Up

NXN 5.164 0.783 0.875 0.878 0.857 0.817 0.954 Mlig455_031389 {REF} {Length: 817} {Pfam: Thioredoxin-like [PF13905.8, score=94.0]; Redoxin [PF08534.12, score=58.9]; AhpC/TSA family [PF00578.23, score=48.2]; Thioredoxin [PF00085.22, score=43.4]; Thioredoxin-like domain [PF13098.8, score=33.4]; Thioredoxin [PF14595.8, score=22.3]; Thioredoxin-like [PF13899.8, score=21.7]} {Human: ENSG00000167693, NXN, nucleoredoxin, [RH, Score=91.7, Expect=4e-22]} {Mouse: ENSMUSG00000020844, Nxn, nucleoredoxin, [RH, Score=93.2, Expect=2e-22]} {Celegans: WBGene00020613, T20D4.7, [RH, Score=121, Expect=1e-35]} {RNA1509_17746, RNA1509_2823, RNA1509_9863} {RNA1310_36941, RNA1509_17746, RNA1509_2823, RNA1509_9863} {RNA1509_17746, RNA1509_2823, RNA1509_9863, RNA815_16980}
10. MligTC455_50334 4713 98.19 Mlig455_047582

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.063/0.00049

5.151 0.751 0.846 0.894 0.952 0.851 0.857 Mlig455_047582 {REF} {Length: 1011} {Pfam: Globin [PF00042.24, score=71.0]} {Smed: dd_Smed_v6_2237_0_1, dd_Smed_v6_2237_0_1, [RH, Score=59.7, Expect=6e-12]} {RNA1509_8100} {RNA1310_38363} {RNA815_18105}
11. MligTC455_33808 22456 467.83 Mlig455_061945

Neo: -

Age: -

MOXD1 5.112 0.707 0.841 0.922 0.965 0.835 0.842 Mlig455_061945 {REF} {Length: 2202} {TRANSSPLICED} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=92.1]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=68.1]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=120, Expect=5e-28]; ENSG00000123454, DBH, dopamine beta-hydroxylase, [Score=117, Expect=7e-27]} {Mouse: ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=135, Expect=5e-33]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=127, Expect=1e-30]} {Celegans: WBGene00006541, tbh-1, Tyramine beta-hydroxylase, [Score=139, Expect=7e-35]} {Smed: dd_Smed_v6_42610_0_1, dd_Smed_v6_42610_0_1, [Score=118, Expect=8e-29]} {RNA1509_127} {RNA1310_11166.1} {RNA815_4383.1}
12. MligTC455_20144 1943 40.48 Mlig455_007028, Mlig455_007029, Mlig455_069137

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.663

Region-enriched R2: 1.755/0.00284

Regeneration-downregulated BL: -2.689

Regeneration-depleted BL: -2.689

4.267 - 0.792 0.835 0.966 0.856 0.818

Mlig455_007028 {REF} {Length: 1192} {NoTransDecoderORF} {RNA1509_19530, RNA1509_24021} {RNA1310_20554, RNA1509_19530, RNA1509_24021} {RNA1509_19530, RNA1509_24021, RNA815_8810.1}

Mlig455_007029 {REF} {Length: 915} {RNA1509_30060} {RNA1310_40388.1} {RNA815_20453}

Mlig455_069137 {REF} {Length: 3938} {RNA1509_4350} {RNA1310_20554} {RNA815_8810.1}
13. MligTC455_40024 3395 70.74 Mlig455_058212

Neo: -

Age: logFC(26M/2M)=-0.531

ODF3 4.22 - 0.895 0.858 0.971 0.795 0.701 Mlig455_058212 {REF} {Length: 1436} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=65.8]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=179, Expect=2e-55]; ENSG00000177989, ODF3B, outer dense fiber of sperm tails 3B, [RH, Score=174, Expect=3e-53]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [Score=172, Expect=1e-52]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=3e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [RH, Score=322, Expect=3e-112]} {RNA1509_14103, RNA1509_4352} {RNA1310_23191, RNA1509_14103, RNA1509_4352} {RNA1509_14103, RNA1509_4352, RNA815_9849}
14. MligTC455_37361 5370 111.88 Mlig455_043035

Neo: -

Age: logFC(26M/2M)=-0.378

CFAP52 4.164 0.775 0.806 0.770 0.958 0.855 - Mlig455_043035 {REF} {Length: 2490} {Pfam: WD domain, G-beta repeat [PF00400.34, score=123.9]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.1]; WD40-like domain [PF17005.7, score=27.1]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=757, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=441, Expect=1e-145]} {Celegans: WBGene00004895, smu-1, SMU-1; Suppressor of Mec and Unc defects, [Score=60.5, Expect=2e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=841, Expect=0.0]} {RNA1509_1341} {RNA1310_8859, RNA1509_1341} {RNA1509_1341, RNA815_2855}
15. MligTC455_37360 5178 107.87 Mlig455_043000

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.956

CFAP52 4.146 0.778 0.808 0.757 0.952 0.851 - Mlig455_043000 {REF} {Length: 2520} {Pfam: WD domain, G-beta repeat [PF00400.34, score=124.0]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=41.8]; WD40-like domain [PF17005.7, score=26.5]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=748, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=756, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=439, Expect=3e-145]} {Celegans: WBGene00022119, copa-1, Coatomer subunit alpha, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=838, Expect=0.0]} {RNA1509_1341} {RNA1310_8859} {RNA815_2855}
16. MligTC455_49393 893 18.6 Mlig455_003601

Neo: -

Age: -

Region-enriched R2: 1.237/0.01562

Regeneration-downregulated BL: -2.400

Regeneration-depleted BL: -2.400

4.112 0.721 0.893 - 0.953 0.823 0.722 Mlig455_003601 {REF} {Length: 910} {Pfam: Normal lung function maintenance, Low in Lung Cancer 1 protein [PF14945.8, score=24.4]} {Smed: dd_Smed_v6_6024_0_1, dd_Smed_v6_6024_0_1, [Score=98.6, Expect=5e-27]} {RNA1509_38038} {RNA1310_47454} {RNA815_24792.1}
17. MligTC455_36618 545 11.35 Mlig455_020301, Mlig455_020358

Neo: -

Age: logFC(26M/2M)=-0.435

Region-enriched R2: 3.072/0.00097

SLC7A6 4.05 - 0.715 0.748 0.973 0.734 0.880

Mlig455_020301 {REF} {Length: 4137} {Pfam: Amino acid permease [PF13520.8, score=183.8]; Amino acid permease [PF00324.23, score=95.7]} {Human: ENSG00000103064, SLC7A6, solute carrier family 7 member 6, [RH, Score=421, Expect=7e-143]; ENSG00000155465, SLC7A7, solute carrier family 7 member 7, [RH, Score=412, Expect=1e-139]; ENSG00000103257, SLC7A5, solute carrier family 7 member 5, [RH, Score=410, Expect=1e-138]} {Mouse: ENSMUSG00000031904, Slc7a6, solute carrier family 7 (cationic amino acid transporter, y+ system), member 6, [RH, Score=419, Expect=2e-142]; ENSMUSG00000027737, Slc7a11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, [RH, Score=413, Expect=3e-140]; ENSMUSG00000000958, Slc7a7, solute carrier family 7 (cationic amino acid transporter, y+ system), member 7, [RH, Score=410, Expect=4e-139]} {Dmel: FBgn0039844, CG1607, [RH, Score=467, Expect=2e-161]} {Celegans: WBGene00000002, aat-1, Amino Acid Transporter, [RH, Score=431, Expect=1e-147]} {Smed: dd_Smed_v6_2179_0_1, dd_Smed_v6_2179_0_1, [RH, Score=498, Expect=5e-174]} {RNA1509_26498} {RNA1310_9422, RNA1509_26498} {RNA1509_26498, RNA815_5493}

Mlig455_020358 {REF} {Length: 3120} {Pfam: Amino acid permease [PF13520.8, score=147.1]; Amino acid permease [PF00324.23, score=74.6]} {Human: ENSG00000103064, SLC7A6, solute carrier family 7 member 6, [Score=346, Expect=6e-115]; ENSG00000155465, SLC7A7, solute carrier family 7 member 7, [Score=340, Expect=2e-112]} {Mouse: ENSMUSG00000031904, Slc7a6, solute carrier family 7 (cationic amino acid transporter, y+ system), member 6, [Score=340, Expect=9e-113]; ENSMUSG00000000958, Slc7a7, solute carrier family 7 (cationic amino acid transporter, y+ system), member 7, [Score=335, Expect=7e-111]; ENSMUSG00000027737, Slc7a11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, [Score=325, Expect=6e-107]} {Dmel: FBgn0039844, CG1607, [Score=390, Expect=1e-132]} {Celegans: WBGene00000002, aat-1, Amino Acid Transporter, [Score=353, Expect=2e-118]} {Smed: dd_Smed_v6_7207_0_1, dd_Smed_v6_7207_0_1, [Score=416, Expect=3e-143]} {RNA1509_56112} {RNA1310_9422, RNA1509_56112} {RNA1509_56112, RNA815_5493}
18. MligTC455_39515 27644 575.93 Mlig455_031388

Neo: -

Age: -

CAV3 3.603 - - 0.970 0.902 0.848 0.883 Mlig455_031388 {REF} {Length: 1882} {Pfam: Caveolin [PF01146.19, score=124.4]} {Human: ENSG00000182533, CAV3, caveolin 3, [Score=94.4, Expect=5e-25]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [RH, Score=92.4, Expect=2e-24]} {Celegans: WBGene00000302, cav-2, Caveolin-2, [RH, Score=73.9, Expect=2e-17]} {Smed: dd_Smed_v6_877_0_1, dd_Smed_v6_877_0_1, [RH, Score=127, Expect=1e-38]} {RNA1509_1284, RNA1509_15662, RNA1509_257} {RNA1310_50452, RNA1509_1284, RNA1509_15662, RNA1509_257} {RNA1509_1284, RNA1509_15662, RNA1509_257, RNA815_18477}
19. MligTC455_43525 62 1.29 Mlig455_041078

Neo: -

Age: -

3.476 - - 0.786 0.957 0.882 0.851 Mlig455_041078 {REF} {Length: 3896} {RNA1509_39963} {RNA1310_38466} {RNA815_23614}
20. MligTC455_41695 251 5.23 Mlig455_044756

Neo: -

Age: logFC(26M/2M)=-0.724

Regeneration-downregulated R4: -3.389

Regeneration-depleted R4: -3.389

SSUH2 3.457 - 0.772 - 0.974 0.905 0.806 Mlig455_044756 {REF} {Length: 1704} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=186, Expect=9e-55]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=157, Expect=2e-44]} {RNA1509_35286} {RNA1310_22184} {RNA815_11262}
21. MligTC455_25589 1419 29.55 Mlig455_029945

Neo: -

Age: -

Region-enriched R2: 2.293/0.00000

Regeneration-downregulated BL: -3.516

Regeneration-depleted BL: -3.516

3.451 0.837 0.814 - 0.951 - 0.849 Mlig455_029945 {REF} {Length: 1261} {Pfam: Helix-turn-helix domain [PF12645.9, score=19.8]; Domain of unknown function (DUF1848) [PF08902.13, score=19.3]} {RNA1509_17753} {RNA1310_70608, RNA1509_17753} {RNA1509_17753, RNA815_1498.1}
22. MligTC455_19042 3679 76.64 Mlig455_030661

Neo: -

Age: logFC(26M/2M)=0.480

Region-specific R2: 2.811

Region-enriched R2: 1.755/0.00003

CAV1 3.444 0.797 0.863 - 0.957 0.827 - Mlig455_030661 {REF} {Length: 1257} {Pfam: Caveolin [PF01146.19, score=124.8]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=105, Expect=2e-29]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=105, Expect=2e-29]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=81.6, Expect=8e-20]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=144, Expect=1e-45]} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1310_31540, RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522, RNA815_14585}
23. MligTC455_52734 555 11.57 Mlig455_038511

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.535

Region-specific R2: 2.258

Region-enriched R2: 2.161/0.00016

RBM12B 3.439 0.794 - - 0.980 0.882 0.783 Mlig455_038511 {REF} {Length: 3692} {Pfam: Otopetrin [PF03189.15, score=53.6]} {Human: ENSG00000183808, RBM12B, RNA binding motif protein 12B, [Score=63.5, Expect=2e-09]} {RNA1509_57555} {RNA1310_7630.2} {RNA815_2303}
24. MligTC455_52987 980 20.41 Mlig455_054765

Neo: -

Age: logFC(26M/2M)=-0.758

Region-enriched R2: 2.188/0.00290

CALM3 3.412 - - 0.800 0.966 0.865 0.781 Mlig455_054765 {REF} {Length: 759} {Pfam: EF hand [PF00036.34, score=109.0]; EF-hand domain pair [PF13499.8, score=105.1]; EF-hand domain [PF13405.8, score=89.0]; EF-hand domain pair [PF13833.8, score=88.7]; EF hand [PF13202.8, score=71.3]; EF-hand domain [PF14658.8, score=42.3]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=39.9]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=28.8]; EF-hand domain [PF08976.13, score=27.1]} {Human: ENSG00000160014, CALM3, calmodulin 3, [Score=164, Expect=3e-52]; ENSG00000198668, CALM1, calmodulin 1, [Score=164, Expect=3e-52]; ENSG00000143933, CALM2, calmodulin 2, [Score=164, Expect=3e-52]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=164, Expect=2e-52]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=164, Expect=2e-52]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=164, Expect=2e-52]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=159, Expect=2e-50]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=164, Expect=3e-52]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=164, Expect=2e-52]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=164, Expect=2e-52]} {RNA1509_6221} {RNA1310_49203} {RNA815_22421}
25. MligTC455_18451 118 2.46 Mlig455_031824, Mlig455_047676

Neo: -

Age: -

WSCD2 3.406 - 0.735 - 0.952 0.843 0.876

Mlig455_031824 {REF} {Length: 1015} {Pfam: WSC domain [PF01822.21, score=53.3]; PAN domain [PF00024.28, score=21.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=63.2, Expect=6e-11]} {RNA1509_53783} {RNA1310_58580.1} {RNA815_46263}

Mlig455_047676 {REF} {Length: 926} {Pfam: WSC domain [PF01822.21, score=57.9]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=64.3, Expect=2e-11]} {Mouse: ENSMUSG00000020811, Wscd1, WSC domain containing 1, [Score=49.3, Expect=1e-06]} {RNA1310_58580.1}
26. MligTC455_24473 2936 61.17 Mlig455_051348

Neo: -

Age: -

CSMD2 3.38 - 0.723 - 0.961 0.855 0.841 Mlig455_051348 {REF} {Length: 18390} {Pfam: CUB domain [PF00431.22, score=95.4]; Sushi repeat (SCR repeat) [PF00084.22, score=86.7]; Tyrosine-protein kinase ephrin type A/B receptor-like [PF07699.15, score=67.5]; HYR domain [PF02494.18, score=57.6]; Calcium-binding EGF domain [PF07645.17, score=46.6]; Complement Clr-like EGF-like [PF12662.9, score=22.9]; Coagulation Factor Xa inhibitory site [PF14670.8, score=21.3]} {Human: ENSG00000121904, CSMD2, CUB and Sushi multiple domains 2, [Score=103, Expect=1e-20]} {Mouse: ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=96.7, Expect=7e-19]; ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=94.7, Expect=3e-18]; ENSMUSG00000028804, Csmd2, CUB and Sushi multiple domains 2, [Score=92.8, Expect=1e-17]} {Dmel: FBgn0031879, uif, uninflatable, [Score=212, Expect=5e-54]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=214, Expect=1e-54]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=77.4, Expect=1e-13]} {RNA1509_1720, RNA1509_23010} {RNA1310_11.1, RNA1509_1720, RNA1509_23010} {RNA1509_1720, RNA1509_23010, RNA815_7}
27. MligTC455_49394 1184 24.68 Mlig455_041577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.255/0.02823

3.369 - 0.864 - 0.963 0.818 0.724 Mlig455_041577 {REF} {Length: 928} {Pfam: Normal lung function maintenance, Low in Lung Cancer 1 protein [PF14945.8, score=24.7]} {Smed: dd_Smed_v6_6024_0_1, dd_Smed_v6_6024_0_1, [Score=97.8, Expect=1e-26]} {RNA1509_17780, RNA1509_38038} {RNA1310_47454, RNA1509_17780, RNA1509_38038} {RNA1509_17780, RNA1509_38038, RNA815_24792.1}
28. MligTC455_30617 647 13.47 Mlig455_031164

Neo: -

Age: logFC(26M/2M)=-0.513

ITPR1 3.339 - 0.810 0.739 0.964 0.826 - Mlig455_031164 {REF} {Length: 3978} {Pfam: RyR and IP3R Homology associated [PF08454.13, score=75.9]; Ion transport protein [PF00520.33, score=29.6]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=157, Expect=3e-38]} {Mouse: ENSMUSG00000057378, Ryr3, ryanodine receptor 3, [Score=149, Expect=6e-36]; ENSMUSG00000030592, Ryr1, ryanodine receptor 1, skeletal muscle, [Score=148, Expect=1e-35]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=137, Expect=2e-32]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=127, Expect=1e-29]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=598, Expect=0.0]} {RNA1509_42170} {RNA1310_129.1} {RNA815_62.1}
29. MligTC455_30618 652 13.59 Mlig455_031172

Neo: -

Age: logFC(26M/2M)=-0.520

ITPR2 3.32 - 0.807 0.752 0.962 0.799 - Mlig455_031172 {REF} {Length: 9583} {Pfam: RIH domain [PF01365.23, score=93.8]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=76.1]; MIR domain [PF02815.21, score=44.8]} {Human: ENSG00000123104, ITPR2, inositol 1,4,5-trisphosphate receptor type 2, [Score=214, Expect=5e-55]; ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=205, Expect=3e-52]} {Mouse: ENSMUSG00000042644, Itpr3, inositol 1,4,5-triphosphate receptor 3, [Score=222, Expect=2e-57]; ENSMUSG00000030287, Itpr2, inositol 1,4,5-triphosphate receptor 2, [Score=213, Expect=8e-55]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=194, Expect=3e-49]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=140, Expect=7e-33]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1298, Expect=0.0]} {RNA1509_23724, RNA1509_55174, RNA1509_5518} {RNA1310_129.1, RNA1509_23724, RNA1509_55174, RNA1509_5518} {RNA1509_23724, RNA1509_55174, RNA1509_5518, RNA815_62.1}
30. MligTC455_47874 67 1.4 Mlig455_000340

Neo: -

Age: -

3.298 - 0.736 - 0.960 0.789 0.813 Mlig455_000340 {REF} {Length: 1412} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.4, Expect=9e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
31. MligTC455_51199 206 4.29 Mlig455_044015

Neo: -

Age: Down-Up-Down

ARX 3.295 - 0.771 - 0.968 0.704 0.852 Mlig455_044015 {REF} {Length: 1926} {Pfam: Homeodomain [PF00046.31, score=85.3]} {Human: ENSG00000004848, ARX, aristaless related homeobox, [Score=116, Expect=8e-30]} {Mouse: ENSMUSG00000035277, Arx, aristaless related homeobox, [Score=115, Expect=1e-29]} {Dmel: FBgn0008636, hbn, homeobrain, [Score=128, Expect=5e-35]} {Celegans: WBGene00000433, ceh-8, Homeobox protein ceh-8, [RH, Score=103, Expect=6e-27]} {Smed: dd_Smed_v6_16955_0_1, dd_Smed_v6_16955_0_1, [Score=105, Expect=9e-27]} {RNA1509_46102} {RNA1310_37906, RNA1509_46102}
32. MligTC455_47875 72 1.5 Mlig455_067941

Neo: -

Age: -

3.294 - 0.736 - 0.967 0.789 0.802 Mlig455_067941 {REF} {Length: 1399} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.8, Expect=7e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
33. MligTC455_29828 3825 79.69 Mlig455_005927, Mlig455_028571

Neo: -

Age: -

Region-enriched R2: 2.078/0.00752

AOX1 3.26 0.782 - - 0.960 0.815 0.703

Mlig455_005927 {REF} {Length: 5419} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=393.8]; [2Fe-2S] binding domain [PF01799.22, score=95.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=88.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=82.6]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=60.0]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=21.6]} {Human: ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=461, Expect=1e-139]; ENSG00000158125, XDH, xanthine dehydrogenase, [Score=454, Expect=4e-137]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=468, Expect=2e-142]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=449, Expect=1e-135]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=665, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=506, Expect=1e-156]} {RNA1509_1345} {RNA1310_1703.1, RNA1509_1345} {RNA1509_1345, RNA815_528.1}

Mlig455_028571 {REF} {Length: 5081} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=393.8]; [2Fe-2S] binding domain [PF01799.22, score=95.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=88.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=82.6]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=60.0]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=21.6]} {Human: ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=459, Expect=5e-139]; ENSG00000158125, XDH, xanthine dehydrogenase, [Score=453, Expect=6e-137]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=467, Expect=3e-142]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=450, Expect=9e-136]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=665, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=506, Expect=1e-156]} {RNA1509_1345, RNA1509_30386} {RNA1310_1703.1, RNA1509_30386} {RNA1509_30386, RNA815_528.1}
34. MligTC455_22235 6787 141.4 Mlig455_032864

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.356

EFHC2 3.246 - 0.719 - 0.974 0.805 0.748 Mlig455_032864 {REF} {Length: 3541} {Pfam: DUF1126 PH-like domain [PF06565.14, score=338.3]; EF hand [PF00036.34, score=18.1]} {Human: ENSG00000183690, EFHC2, EF-hand domain containing 2, [RH, Score=657, Expect=0.0]} {Mouse: ENSMUSG00000025038, Efhc2, EF-hand domain (C-terminal) containing 2, [RH, Score=663, Expect=0.0]} {Dmel: FBgn0034487, Efhc1.2, EF-hand domain containing 1.2, [RH, Score=417, Expect=7e-135]} {Celegans: WBGene00013028, efhc-1, EF-Hand domain-Containing protein 1 homolog, [Score=97.8, Expect=3e-21]} {Smed: dd_Smed_v6_6035_0_1, dd_Smed_v6_6035_0_1, [RH, Score=829, Expect=0.0]} {RNA1509_6224, RNA1509_965} {RNA1310_5674, RNA1509_965} {RNA1509_965, RNA815_1927.1}
35. MligTC455_26358 428 8.93 Mlig455_012675

Neo: -

Age: logFC(26M/2M)=-0.338

Region-enriched R2: 1.608/0.04280

NOTCH2 2.724 0.856 - - 0.915 0.953 - Mlig455_012675 {REF} {Length: 4700} {Pfam: EGF-like domain [PF00008.29, score=144.8]; Ankyrin repeats (3 copies) [PF12796.9, score=86.3]; Human growth factor-like EGF [PF12661.9, score=80.1]; Ankyrin repeats (many copies) [PF13857.8, score=70.9]; Ankyrin repeat [PF00023.32, score=65.4]; Ankyrin repeats (many copies) [PF13637.8, score=61.9]; Ankyrin repeat [PF13606.8, score=58.6]; LNR domain [PF00066.19, score=52.0]; EGF-like domain [PF07974.15, score=46.9]; Calcium-binding EGF domain [PF07645.17, score=31.9]} {Human: ENSG00000134250, NOTCH2, notch 2, [Score=311, Expect=2e-87]} {Mouse: ENSMUSG00000027878, Notch2, notch 2, [Score=329, Expect=2e-93]} {Dmel: FBgn0004647, N, Notch, [Score=325, Expect=6e-92]} {Celegans: WBGene00003001, lin-12, [Score=242, Expect=2e-65]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=214, Expect=1e-56]} {RNA1509_20447, RNA1509_55795} {RNA1310_1718.1, RNA1509_20447, RNA1509_55795} {RNA1509_20447, RNA1509_55795, RNA815_12429}
36. MligTC455_18322 82 1.71 Mlig455_021228

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.636

2.701 - - 0.889 0.960 0.852 - Mlig455_021228 {REF} {Length: 3954} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=26.3]} {Smed: dd_Smed_v6_11972_0_1, dd_Smed_v6_11972_0_1, [RH, Score=229, Expect=2e-64]} {RNA1509_9124} {RNA1310_5268.1, RNA1509_9124} {RNA1509_9124, RNA815_1717.1}
37. MligTC455_53682 393 8.18 Mlig455_064952, Mlig455_066834

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.926

Region-enriched R2: 4.442/0.00896

2.673 0.857 0.848 - 0.968 - -

Mlig455_064952 {REF} {Length: 1573} {Pfam: PAN domain [PF00024.28, score=20.0]} {RNA1310_33258} {RNA815_17150}

Mlig455_066834 {REF} {Length: 1573} {Pfam: PAN domain [PF00024.28, score=20.0]} {RNA1310_33258} {RNA815_17150}
38. MligTC455_39180 256 5.34 Mlig455_057231

Neo: -

Age: logFC(26M/2M)=-0.449

TCTE3 2.666 - - 0.864 0.950 0.852 - Mlig455_057231 {REF} {Length: 1057} {Pfam: Tctex-1 family [PF03645.15, score=43.3]} {Human: ENSG00000275368, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=67.8, Expect=2e-13]; ENSG00000184786, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=67.8, Expect=2e-13]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [Score=61.2, Expect=2e-11]; ENSMUSG00000079710, Gm3448, predicted gene 3448, [Score=59.3, Expect=1e-10]; ENSMUSG00000079707, Tcte3, t-complex-associated testis expressed 3, [Score=59.3, Expect=1e-10]; ENSMUSG00000116780, Gm3417, predicted gene 3417, [Score=58.5, Expect=2e-10]} {Smed: dd_Smed_v6_9036_0_1, dd_Smed_v6_9036_0_1, [Score=92.4, Expect=2e-23]} {RNA1509_34873, RNA1509_48552} {RNA1310_34743, RNA1509_34873, RNA1509_48552} {RNA1509_34873, RNA1509_48552, RNA815_18661}
39. MligTC455_29030 141 2.93 Mlig455_061986

Neo: -

Age: logFC(26M/2M)=-0.349

Region-enriched R2: 5.117/0.03372

FZD5 2.663 - - 0.818 0.964 0.881 - Mlig455_061986 {REF} {Length: 3701} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=386.1]; Fz domain [PF01392.24, score=95.9]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=582, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=586, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=545, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=388, Expect=7e-127]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [RH, Score=556, Expect=0.0]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
40. MligTC455_26585 173 3.61 Mlig455_061024

Neo: -

Age: -

2.66 - - 0.868 0.969 0.823 - Mlig455_061024 {REF} {Length: 2825} {RNA1509_19437} {RNA1310_38787} {RNA815_16416}
41. MligTC455_41694 404 8.41 Mlig455_026434, Mlig455_026464

Neo: -

Age: -

SSUH2 2.648 - 0.851 - 0.957 0.840 -

Mlig455_026434 {REF} {Length: 1709} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=210, Expect=4e-64]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=177, Expect=5e-52]} {RNA1509_35286} {RNA1310_19837, RNA1509_35286} {RNA1509_35286, RNA815_11262}

Mlig455_026464 {REF} {Length: 1584} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=210, Expect=7e-64]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=178, Expect=4e-52]} {RNA1509_35286} {RNA1310_19837} {RNA815_11262}
42. MligTC455_26986 157 3.28 Mlig455_058044

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.496

2.643 - - 0.954 0.889 0.800 - Mlig455_058044 {REF} {Length: 3183} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=51.3]; Ceramide kinase C-terminal domain [PF19280.1, score=22.6]} {Mouse: ENSMUSG00000075256, Cerkl, ceramide kinase-like, [Score=55.1, Expect=2e-07]} {Dmel: FBgn0037315, Cerk, Ceramide kinase, [Score=52.4, Expect=1e-06]} {RNA1509_33630, RNA1509_39108} {RNA1310_4577, RNA1509_33630, RNA1509_39108} {RNA1509_33630, RNA1509_39108, RNA815_1173}
43. MligTC455_47244 216 4.49 Mlig455_016130

Neo: -

Age: -

Region-enriched R2: 3.391/0.02151
Region-enriched R6: 2.922/0.03099

2.64 - - - 0.955 0.875 0.810 Mlig455_016130 {REF} {Length: 3312} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=27.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=20.5]} {Smed: dd_Smed_v6_24733_0_1, dd_Smed_v6_24733_0_1, [RH, Score=231, Expect=1e-71]} {RNA1509_41111} {RNA1310_18481.1} {RNA815_10445}
44. MligTC455_20949 5538 115.36 Mlig455_001658

Neo: -

Age: logFC(26M/2M)=-0.358

DNAL4 2.631 - - - 0.789 0.952 0.890 Mlig455_001658 {REF} {Length: 876} {Pfam: Dynein light chain type 1 [PF01221.20, score=95.1]} {Human: ENSG00000100246, DNAL4, dynein axonemal light chain 4, [RH, Score=160, Expect=4e-52]} {Mouse: ENSMUSG00000022420, Dnal4, dynein, axonemal, light chain 4, [RH, Score=160, Expect=2e-52]} {Dmel: FBgn0033687, CG8407, [RH, Score=147, Expect=2e-47]} {Celegans: WBGene00001005, dlc-1, Dynein light chain 1, cytoplasmic, [Score=68.2, Expect=2e-16]} {Smed: dd_Smed_v6_2487_0_1, dd_Smed_v6_2487_0_1, [RH, Score=168, Expect=5e-56]} {RNA1509_10642, RNA1509_17811, RNA1509_20785, RNA1509_7856} {RNA1310_39462, RNA1509_10642, RNA1509_17811, RNA1509_20785, RNA1509_7856} {RNA1509_10642, RNA1509_17811, RNA1509_20785, RNA1509_7856, RNA815_24967.1}
45. MligTC455_29508 144 3 Mlig455_003167

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.434

2.618 - 0.818 - 0.956 0.844 - Mlig455_003167 {REF} {Length: 1270} {Pfam: Interferon-induced 6-16 family [PF06140.15, score=24.5]} {RNA1509_46297} {RNA1310_35782} {RNA815_17641.2}
46. MligTC455_16015 85 1.78 Mlig455_057827

Neo: -

Age: -

SLC6A3 2.608 - - 0.956 0.786 0.866 - Mlig455_057827 {REF} {Length: 3250} {tRNA: Undet(NNN),pseudo, score=20.8} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=587.0]} {Human: ENSG00000276996, SLC6A3, solute carrier family 6 member 3, [Score=520, Expect=2e-177]; ENSG00000142319, SLC6A3, solute carrier family 6 member 3, [Score=520, Expect=2e-177]; ENSG00000103546, SLC6A2, solute carrier family 6 member 2, [Score=506, Expect=5e-172]} {Mouse: ENSMUSG00000021609, Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, [Score=523, Expect=1e-178]; ENSMUSG00000055368, Slc6a2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, [Score=513, Expect=6e-175]} {Dmel: FBgn0034136, DAT, Dopamine transporter, [Score=471, Expect=2e-158]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=432, Expect=2e-143]} {Smed: dd_Smed_v6_22486_0_1, dd_Smed_v6_22486_0_1, [Score=573, Expect=0.0]} {RNA1509_41282} {RNA1310_11169} {RNA815_3966}
47. MligTC455_29045 127 2.65 Mlig455_056054

Neo: -

Age: -

Region-enriched R2: 4.858/0.00652

FZD5 2.588 - 0.842 0.781 0.965 - - Mlig455_056054 {REF} {Length: 3655} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=389.0]; Fz domain [PF01392.24, score=85.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=554, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [Score=561, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=516, Expect=5e-176]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=368, Expect=3e-120]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [Score=522, Expect=7e-178]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
48. MligTC455_50769 157 3.28 Mlig455_011755, Mlig455_019899, Mlig455_047969

Neo: -

Age: -

ROR1, ROR2 2.572 - 0.782 0.821 0.969 - -

Mlig455_011755 {REF} {Length: 2365} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=250.7]; Protein kinase domain [PF00069.27, score=106.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=328, Expect=5e-102]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=331, Expect=7e-103]} {Dmel: FBgn0010407, Ror, [RH, Score=300, Expect=1e-93]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=228, Expect=4e-65]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=307, Expect=7e-95]} {RNA1509_34377} {RNA1310_12745} {RNA815_11383}

Mlig455_019899 {REF} {Length: 3742} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=248.8]; Protein kinase domain [PF00069.27, score=103.2]; Immunoglobulin I-set domain [PF07679.18, score=46.1]; Immunoglobulin domain [PF13927.8, score=44.2]; Immunoglobulin domain [PF00047.27, score=28.0]; Immunoglobulin domain [PF13895.8, score=27.3]; Fz domain [PF01392.24, score=27.0]; Kringle domain [PF00051.20, score=23.5]} {Human: ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [Score=393, Expect=1e-120]} {Mouse: ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=393, Expect=5e-121]} {Dmel: FBgn0010407, Ror, [RH, Score=300, Expect=3e-89]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=291, Expect=4e-84]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=439, Expect=2e-139]} {RNA1509_34377} {RNA1310_12745, RNA1509_34377} {RNA1509_34377, RNA815_11383}

Mlig455_047969 {REF} {Length: 3775} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=248.3]; Protein kinase domain [PF00069.27, score=104.3]; Immunoglobulin I-set domain [PF07679.18, score=46.2]; Immunoglobulin domain [PF13927.8, score=44.1]; Immunoglobulin domain [PF00047.27, score=28.0]; Immunoglobulin domain [PF13895.8, score=27.3]; Fz domain [PF01392.24, score=27.1]; Kringle domain [PF00051.20, score=22.3]} {Human: ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [Score=387, Expect=7e-119]} {Mouse: ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=386, Expect=1e-118]} {Dmel: FBgn0010407, Ror, [RH, Score=297, Expect=4e-88]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=285, Expect=5e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=441, Expect=3e-140]} {RNA1509_34377} {RNA1310_12745} {RNA815_11383}
49. MligTC455_22150 189 3.94 Mlig455_054947

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.071

XDH 2.564 - - 0.757 0.959 0.848 - Mlig455_054947 {REF} {Length: 5481} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=346.4]; [2Fe-2S] binding domain [PF01799.22, score=95.7]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=91.5]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=51.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=47.3]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=25.1]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=476, Expect=9e-146]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=471, Expect=4e-144]; ENSMUSG00000079554, Aox2, aldehyde oxidase 2, [Score=457, Expect=7e-139]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=456, Expect=1e-138]; ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=449, Expect=5e-136]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=640, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=485, Expect=1e-149]} {RNA1509_325, RNA1509_38160} {RNA1310_1603.1, RNA1509_38160} {RNA1509_38160, RNA815_224.2}
50. MligTC455_44301 1697 35.36 Mlig455_000545

Neo: -

Age: -

2.563 - 0.739 - 0.959 0.865 - Mlig455_000545 {REF} {Length: 1706} {TRANSSPLICED} {Smed: dd_Smed_v6_6108_0_1, dd_Smed_v6_6108_0_1, [RH, Score=190, Expect=9e-63]} {RNA1509_16536, RNA1509_27118, RNA1509_9934} {RNA1310_30744, RNA1509_16536, RNA1509_27118, RNA1509_9934} {RNA1509_16536, RNA1509_27118, RNA1509_9934, RNA815_13864}
51. MligTC455_16874 38 0.8 Mlig455_028170

Neo: -

Age: -

KCNK18 2.552 - - 0.804 0.953 0.795 - Mlig455_028170 {REF} {Length: 2452} {Pfam: Ion channel [PF07885.18, score=103.1]; Protein of unknown function (DUF3112) [PF11309.10, score=20.2]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [Score=96.7, Expect=1e-21]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=2e-23]} {Dmel: FBgn0033257, sand, sandman, [Score=129, Expect=2e-33]} {Celegans: WBGene00006680, twk-28, TWiK family of potassium channels, [Score=144, Expect=3e-38]} {Smed: dd_Smed_v6_17586_0_1, dd_Smed_v6_17586_0_1, [Score=270, Expect=2e-87]} {RNA1509_39975} {RNA1310_18301.1} {RNA815_12440}
52. MligTC455_50665 48 0.99 Mlig455_032812

Neo: -

Age: -

2.541 0.738 0.841 - 0.962 - - Mlig455_032812 {REF} {Length: 1550} {Pfam: Glycine rich protein [PF12810.9, score=23.7]} {RNA1310_48243.1} {RNA815_30313.2}
53. MligTC455_21755 70 1.47 Mlig455_021213

Neo: -

Age: -

2.535 - 0.813 - 0.953 0.769 - Mlig455_021213 {REF} {Length: 4215} {Pfam: F5/8 type C domain [PF00754.27, score=55.5]} {RNA1509_2515} {RNA1310_33166} {RNA815_14716}
54. MligTC455_17817 83 1.73 Mlig455_048691

Neo: -

Age: -

2.534 0.754 0.829 - 0.951 - - Mlig455_048691 {REF} {Length: 1160} {RNA1509_48973} {RNA1310_39954.1} {RNA815_19596}
55. MligTC455_37793 353 7.36 Mlig455_066109, Mlig455_068663

Neo: -

Age: Up-Down-Down

HMCN1 2.532 0.741 - - 0.950 0.841 -

Mlig455_066109 {REF} {Length: 7924} {Pfam: Thrombospondin type 1 domain [PF00090.21, score=408.1]; Spondin-like TSP1 domain [PF19028.2, score=285.5]; Polycystin cation channel [PF08016.14, score=239.7]; PLAT/LH2 domain [PF01477.25, score=86.7]; Thrombospondin type 1 domain [PF19030.2, score=78.4]; Ion transport protein [PF00520.33, score=42.7]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=360, Expect=8e-99]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=363, Expect=7e-100]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [Score=199, Expect=5e-51]} {Celegans: WBGene00000082, adt-1, ADAMTS family; ADT-1, [RH, Score=306, Expect=4e-84]} {Smed: dd_Smed_v6_13975_0_1, dd_Smed_v6_13975_0_1, [RH, Score=944, Expect=0.0]} {RNA1509_9601} {RNA1310_488} {RNA815_1711}

Mlig455_068663 {REF} {Length: 7866} {Pfam: Thrombospondin type 1 domain [PF00090.21, score=423.7]; Spondin-like TSP1 domain [PF19028.2, score=299.7]; Thrombospondin type 1 domain [PF19030.2, score=92.3]; PLAT/LH2 domain [PF01477.25, score=23.1]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=338, Expect=1e-94]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=341, Expect=9e-96]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [Score=189, Expect=2e-48]} {Celegans: WBGene00000082, adt-1, ADAMTS family; ADT-1, [RH, Score=303, Expect=2e-84]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=282, Expect=3e-77]} {RNA1509_9601} {RNA1310_488} {RNA815_1711}
56. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 2.522 - 0.855 - 0.952 0.715 -

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
57. MligTC455_16503 1059 22.07 Mlig455_021794

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.520

Region-enriched R2: 1.466/0.04615

Regeneration-downregulated R6: -2.893

Regeneration-depleted R6: -2.893

2.518 - - 0.725 0.971 0.822 - Mlig455_021794 {REF} {Length: 2949} {RNA1509_22031, RNA1509_7123} {RNA1310_9167, RNA1509_22031, RNA1509_7123} {RNA1509_22031, RNA1509_7123, RNA815_5039.1}
58. MligTC455_17464 409 8.52 Mlig455_048989, Mlig455_049006, Mlig455_067762

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.512

Regeneration-downregulated BL: -7.800

Regeneration-depleted BL: -7.800

2.511 - 0.796 - 0.968 0.747 -

Mlig455_048989 {REF} {Length: 1272} {RNA1310_37715} {RNA815_39767}

Mlig455_049006 {REF} {Length: 1028} {RNA1310_37715} {RNA815_39767}

Mlig455_067762 {REF} {Length: 1353} {RNA1310_37715} {RNA815_39767}
59. MligTC455_39874 143 2.98 Mlig455_049425

Neo: -

Age: -

PKDCC 2.509 - - - 0.953 0.843 0.713 Mlig455_049425 {REF} {Length: 3789} {Pfam: Protein-kinase domain of FAM69 [PF12260.10, score=30.6]; Protein kinase domain [PF00069.27, score=21.0]} {Human: ENSG00000162878, PKDCC, protein kinase domain containing, cytoplasmic, [RH, Score=192, Expect=4e-55]} {Mouse: ENSMUSG00000024247, Pkdcc, protein kinase domain containing, cytoplasmic, [RH, Score=180, Expect=9e-51]} {RNA1310_12305} {RNA815_19030.1}
60. MligTC455_23346 389 8.1 Mlig455_018766

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.603

Regeneration-downregulated R6: -2.996

Regeneration-depleted R6: -2.996

2.498 0.702 - - 0.840 0.956 - Mlig455_018766 {REF} {Length: 921} {RNA1509_14088} {RNA1310_35033} {RNA815_47972}
61. MligTC455_31117 933 19.44 Mlig455_017721, Mlig455_057064, Mlig455_057078

Neo: -

Age: logFC(26M/2M)=-0.670

Region-enriched R2: 1.818/0.04375

ADAM33, ADAM9 2.487 - - - 0.973 0.747 0.767

Mlig455_017721 {REF} {Length: 3292} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=127.8]; Metallo-peptidase family M12 [PF13688.8, score=71.8]; Disintegrin [PF00200.25, score=68.3]; ADAM cysteine-rich [PF08516.14, score=60.1]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=40.8]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=37.1]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=30.2]; Matrixin [PF00413.26, score=19.9]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [RH, Score=244, Expect=5e-69]} {Mouse: ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [RH, Score=254, Expect=3e-73]; ENSMUSG00000050190, Gm5346, predicted gene 5346, [RH, Score=251, Expect=7e-72]} {Dmel: FBgn0265140, Meltrin, [Score=272, Expect=3e-78]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [RH, Score=251, Expect=5e-71]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=225, Expect=1e-61]} {RNA1509_21514, RNA1509_7654} {RNA1310_9319.1, RNA1509_21514, RNA1509_7654} {RNA1509_21514, RNA1509_7654, RNA815_4173.1}

Mlig455_057064 {REF} {Length: 3604} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=128.4]; Metallo-peptidase family M12 [PF13688.8, score=69.3]; Disintegrin [PF00200.25, score=68.6]; ADAM cysteine-rich [PF08516.14, score=60.7]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=42.0]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=37.2]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=31.5]; Matrixin [PF00413.26, score=19.9]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [RH, Score=247, Expect=9e-71]} {Mouse: ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=256, Expect=1e-74]} {Dmel: FBgn0265140, Meltrin, [Score=270, Expect=2e-78]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=248, Expect=7e-71]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=226, Expect=7e-63]} {RNA1509_44914} {RNA1310_9319.1, RNA1509_44914} {RNA1509_44914, RNA815_4173.1}

Mlig455_057078 {REF} {Length: 1339} {Pfam: ADAM cysteine-rich [PF08516.14, score=75.6]; Disintegrin [PF00200.25, score=53.3]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=145, Expect=6e-38]; ENSG00000168594, ADAM29, ADAM metallopeptidase domain 29, [Score=145, Expect=1e-37]; ENSG00000139985, ADAM21, ADAM metallopeptidase domain 21, [Score=143, Expect=5e-37]; ENSG00000143537, ADAM15, ADAM metallopeptidase domain 15, [Score=142, Expect=8e-37]} {Mouse: ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=137, Expect=5e-35]; ENSMUSG00000028041, Adam15, a disintegrin and metallopeptidase domain 15 (metargidin), [Score=137, Expect=3e-35]; ENSMUSG00000011256, Adam19, a disintegrin and metallopeptidase domain 19 (meltrin beta), [Score=137, Expect=3e-35]; ENSMUSG00000046258, Adam29, a disintegrin and metallopeptidase domain 29, [Score=137, Expect=3e-35]; ENSMUSG00000008438, Adam21, a disintegrin and metallopeptidase domain 21, [Score=135, Expect=2e-34]; ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [Score=134, Expect=5e-34]; ENSMUSG00000062438, Adam1b, a disintegrin and metallopeptidase domain 1b, [Score=134, Expect=3e-34]; ENSMUSG00000031553, Adam3, a disintegrin and metallopeptidase domain 3 (cyritestin), [Score=133, Expect=1e-33]; ENSMUSG00000063900, Adam26b, a disintegrin and metallopeptidase domain 26B, [Score=131, Expect=3e-33]} {Dmel: FBgn0265140, Meltrin, [Score=153, Expect=1e-40]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=133, Expect=6e-34]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=132, Expect=1e-33]} {RNA1509_44914} {RNA1310_9319.1} {RNA815_4173.1}
62. MligTC455_17559 113 2.35 Mlig455_022887

Neo: -

Age: logFC(26M/2M)=-0.413

2.479 - - 0.763 0.955 - 0.761 Mlig455_022887 {REF} {Length: 2777} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=73.3]; Tetratricopeptide repeat [PF07719.19, score=51.2]; Tetratricopeptide repeat [PF13176.8, score=34.6]; Tetratricopeptide repeat [PF00515.30, score=29.0]; Tetratricopeptide repeat [PF13181.8, score=25.2]; Tetratricopeptide repeat [PF13428.8, score=19.6]} {RNA1509_46877, RNA1509_58896} {RNA1310_8825.1, RNA1509_46877, RNA1509_58896} {RNA1509_46877, RNA1509_58896, RNA815_1864.1}
63. MligTC455_27520 1983 41.32 Mlig455_050045, Mlig455_054023

Neo: -

Age: logFC(26M/2M)=-0.596

ABCG2 2.47 - 0.719 - 0.956 0.795 -

Mlig455_050045 {REF} {Length: 2545} {Pfam: ABC-2 type transporter [PF01061.26, score=101.6]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=89.7, Expect=9e-19]} {Mouse: ENSMUSG00000032131, Abcg4, ATP binding cassette subfamily G member 4, [Score=87.4, Expect=4e-18]} {Dmel: FBgn0020445, E23, Early gene at 23, [Score=157, Expect=9e-42]} {Celegans: WBGene00015479, wht-1, ABC transporter ATP-binding protein/permease wht-1, [Score=78.2, Expect=2e-15]} {Smed: dd_Smed_v6_4142_0_1, dd_Smed_v6_4142_0_1, [Score=76.3, Expect=2e-15]} {RNA1509_2777} {RNA1310_8975.1} {RNA815_1994.2}

Mlig455_054023 {REF} {Length: 3295} {Pfam: ABC transporter [PF00005.29, score=96.5]; ABC-2 type transporter [PF01061.26, score=79.8]; ABC-2 type transporter [PF19055.2, score=50.3]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=25.7]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=212, Expect=1e-60]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=212, Expect=5e-61]; ENSMUSG00000024254, Abcg8, ATP binding cassette subfamily G member 8, [Score=202, Expect=7e-57]} {Dmel: FBgn0020445, E23, Early gene at 23, [Score=333, Expect=4e-103]} {Celegans: WBGene00015479, wht-1, ABC transporter ATP-binding protein/permease wht-1, [Score=204, Expect=3e-58]} {Smed: dd_Smed_v6_8560_0_1, dd_Smed_v6_8560_0_1, [Score=196, Expect=7e-55]} {RNA1509_2777} {RNA1310_8975.1, RNA1509_2777} {RNA1509_2777, RNA815_1994.2}
64. MligTC455_34737 1982 41.29 Mlig455_015422

Neo: -

Age: Down-Up-Up

Region-enriched R2: 1.613/0.00073
Region-enriched R3: 1.019/0.03508

2.402 - 0.955 - 0.727 0.720 - Mlig455_015422 {REF} {Length: 1098} {Pfam: Stathmin family [PF00836.21, score=49.5]} {Smed: dd_Smed_v6_512_0_1, dd_Smed_v6_512_0_1, [RH, Score=80.5, Expect=2e-21]} {RNA1509_6791} {RNA1310_32272} {RNA815_831}
65. MligTC455_51051 233 4.85 Mlig455_046293

Neo: -

Age: -

2.371 - 0.703 - 0.960 0.708 - Mlig455_046293 {REF} {Length: 1585} {RNA1310_32253}
66. MligTC455_24472 738 15.38 Mlig455_039540

Neo: -

Age: Up-Down-Down

CSMD2 1.896 - - - 0.973 - 0.923 Mlig455_039540 {REF} {Length: 18394} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=107.2]; CUB domain [PF00431.22, score=96.4]; Calcium-binding EGF domain [PF07645.17, score=47.4]; Complement Clr-like EGF-like [PF12662.9, score=23.2]; Coagulation Factor Xa inhibitory site [PF14670.8, score=22.1]} {Human: ENSG00000121904, CSMD2, CUB and Sushi multiple domains 2, [Score=103, Expect=8e-21]} {Mouse: ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=97.1, Expect=5e-19]; ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=95.5, Expect=2e-18]; ENSMUSG00000028804, Csmd2, CUB and Sushi multiple domains 2, [Score=93.6, Expect=6e-18]} {Dmel: FBgn0031879, uif, uninflatable, [Score=207, Expect=1e-52]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=210, Expect=1e-53]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=77.4, Expect=1e-13]} {RNA1509_104, RNA1509_1720} {RNA1310_11.1, RNA1509_104} {RNA1509_104, RNA815_7}
67. MligTC455_43534 34 0.71 Mlig455_030976

Neo: -

Age: -

1.87 - - 0.898 0.972 - - Mlig455_030976 {REF} {Length: 1067} {RNA1310_40722} {RNA815_46396}
68. MligTC455_49490 48 1 Mlig455_054769

Neo: -

Age: -

1.829 - - - 0.964 0.865 - Mlig455_054769 {REF} {Length: 1663} {RNA1509_22234} {RNA1310_23973} {RNA815_10832}
69. MligTC455_45703 433 9.03 Mlig455_018343

Neo: -

Age: -

Region-enriched R2: 1.674/0.02931

ADAM12 1.828 - - 0.868 0.960 - - Mlig455_018343 {REF} {Length: 4207} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=123.1]; Disintegrin [PF00200.25, score=73.1]; Metallo-peptidase family M12 [PF13688.8, score=48.1]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=40.5]; ADAM cysteine-rich [PF08516.14, score=39.9]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=39.4]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=37.8]} {Human: ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=231, Expect=4e-64]; ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=230, Expect=2e-63]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=229, Expect=9e-64]; ENSG00000139985, ADAM21, ADAM metallopeptidase domain 21, [Score=224, Expect=1e-61]; ENSG00000069206, ADAM7, ADAM metallopeptidase domain 7, [Score=222, Expect=1e-60]; ENSG00000042980, ADAM28, ADAM metallopeptidase domain 28, [Score=222, Expect=1e-60]} {Mouse: ENSMUSG00000054555, Adam12, a disintegrin and metallopeptidase domain 12 (meltrin alpha), [Score=228, Expect=3e-62]; ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=226, Expect=4e-62]; ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [Score=224, Expect=3e-61]} {Dmel: FBgn0265140, Meltrin, [Score=247, Expect=1e-68]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=219, Expect=3e-59]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=222, Expect=6e-60]} {RNA1509_54780, RNA1509_7145} {RNA1310_4464.2, RNA1509_54780} {RNA1509_54780, RNA815_1440.1}
70. MligTC455_47948 100 2.07 Mlig455_005840

Neo: -

Age: -

Region-enriched R2: 3.643/0.03527

TSPAN16 1.82 - 0.839 - 0.981 - - Mlig455_005840 {REF} {Length: 2130} {Pfam: Tetraspanin family [PF00335.22, score=86.4]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=48.1, Expect=6e-06]} {Mouse: ENSMUSG00000025351, Cd63, CD63 antigen, [Score=50.4, Expect=7e-07]} {Dmel: FBgn0036769, Tsp74F, Tetraspanin 74F, [Score=68.2, Expect=4e-13]} {Smed: dd_Smed_v6_854_1_1, dd_Smed_v6_854_1_1, [Score=119, Expect=5e-32]} {RNA1509_35459} {RNA1310_22253, RNA1509_35459} {RNA1509_35459, RNA815_11065}
71. MligTC455_35943 122 2.55 Mlig455_062123

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.634

FEZF2 1.814 - - - 0.953 0.861 - Mlig455_062123 {REF} {Length: 3163} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=87.7]; Zinc-finger double domain [PF13465.8, score=71.3]; C2H2-type zinc finger [PF13894.8, score=56.0]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=25.4]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=23.1]; C2H2-type zinc finger [PF13912.8, score=21.6]} {Human: ENSG00000153266, FEZF2, FEZ family zinc finger 2, [RH, Score=337, Expect=3e-107]; ENSG00000128610, FEZF1, FEZ family zinc finger 1, [RH, Score=330, Expect=6e-105]} {Mouse: ENSMUSG00000021743, Fezf2, Fez family zinc finger 2, [RH, Score=341, Expect=7e-109]; ENSMUSG00000029697, Fezf1, Fez family zinc finger 1, [RH, Score=330, Expect=1e-104]} {Dmel: FBgn0031375, erm, earmuff, [RH, Score=343, Expect=2e-107]} {Celegans: WBGene00012639, fezf-1, FEZ Family zinc finger protein, [RH, Score=293, Expect=5e-94]} {Smed: dd_Smed_v6_26394_0_1, dd_Smed_v6_26394_0_1, [RH, Score=287, Expect=9e-92]} {RNA1310_14572} {RNA815_32467}
72. MligTC455_16416 290 6.04 Mlig455_000468

Neo: -

Age: -

Region-enriched R2: 2.225/0.04782

ROR1 1.813 - 0.863 - 0.950 - - Mlig455_000468 {REF} {Length: 2686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=208.1]; Protein kinase domain [PF00069.27, score=77.3]; Kringle domain [PF00051.20, score=19.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=300, Expect=1e-89]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=295, Expect=2e-87]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=281, Expect=2e-82]} {Dmel: FBgn0010407, Ror, [Score=259, Expect=2e-76]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=217, Expect=2e-60]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=328, Expect=1e-100]} {RNA1509_35395} {RNA1310_13558} {RNA815_27446}
73. MligTC455_34475 78 1.63 Mlig455_046323, Mlig455_068223

Neo: -

Age: -

1.809 - - - 0.953 0.856 -

Mlig455_046323 {REF} {Length: 3665} {Smed: dd_Smed_v6_13778_0_1, dd_Smed_v6_13778_0_1, [RH, Score=66.6, Expect=7e-11]} {RNA1310_10926} {RNA815_30720}

Mlig455_068223 {REF} {Length: 2793} {Smed: dd_Smed_v6_13778_0_1, dd_Smed_v6_13778_0_1, [RH, Score=65.9, Expect=8e-11]} {RNA1310_10926} {RNA815_30720}
74. MligTC455_46395 870 18.13 Mlig455_069471

Neo: -

Age: logFC(26M/2M)=0.458

PKD2 1.8 - 0.843 - 0.957 - - Mlig455_069471 {REF} {Length: 3122} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.8]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=750, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=8e-123]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
75. MligTC455_13171 25 0.53 Mlig455_005963, Mlig455_005967

Neo: -

Age: -

1.797 - - - 0.955 0.842 -

Mlig455_005963 {REF} {Length: 2617} {RNA1509_20946} {RNA1310_146331} {RNA815_35450}

Mlig455_005967 {REF} {Length: 1405} {Pfam: Lectin C-type domain [PF00059.23, score=20.7]} {RNA1509_20946} {RNA1310_146331} {RNA815_35450}
76. MligTC455_43581 177 3.68 Mlig455_042725, Mlig455_042827, Mlig455_063146

Neo: -

Age: Up-Down-Down

GRIA2 1.797 - - - 0.958 0.839 -

Mlig455_042725 {REF} {Length: 3074} {Pfam: Ligand-gated ion channel [PF00060.28, score=104.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.7]; Receptor family ligand binding region [PF01094.30, score=33.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=153, Expect=1e-37]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=149, Expect=2e-36]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=147, Expect=7e-36]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=152, Expect=2e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=148, Expect=3e-36]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=147, Expect=8e-36]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=2e-35]} {Dmel: FBgn0038837, CG3822, [Score=140, Expect=5e-34]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=253, Expect=2e-76]} {RNA1310_25150} {RNA815_13942}

Mlig455_042827 {REF} {Length: 2869} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.9]; Receptor family ligand binding region [PF01094.30, score=49.8]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.3]; Iron-containing alcohol dehydrogenase [PF13685.8, score=18.6]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=125, Expect=6e-29]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=122, Expect=5e-28]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=121, Expect=7e-28]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=120, Expect=2e-27]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=125, Expect=5e-29]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=122, Expect=4e-28]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=121, Expect=1e-27]; ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=120, Expect=1e-27]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=119, Expect=3e-27]} {Dmel: FBgn0039927, CG11155, [Score=127, Expect=7e-30]} {Celegans: WBGene00001612, glr-1, Glutamate receptor 1, [Score=103, Expect=1e-22]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=217, Expect=2e-63]} {RNA1310_25150} {RNA815_13942}

Mlig455_063146 {REF} {Length: 2444} {Pfam: Receptor family ligand binding region [PF01094.30, score=35.8]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=82.4, Expect=1e-16]} {RNA1310_25150} {RNA815_13999}
77. MligTC455_09830 66 1.37 Mlig455_040902

Neo: -

Age: -

1.772 - - - 0.957 0.815 - Mlig455_040902 {REF} {Length: 1141} {RNA1310_66500} {RNA815_46507}
78. MligTC455_42503 20 0.41 Mlig455_051969

Neo: -

Age: -

1.767 - - 0.814 0.953 - - Mlig455_051969 {REF} {Length: 1296} {RNA1509_45595} {RNA1310_54539} {RNA815_44342}
79. MligTC455_33851 274 5.72 Mlig455_010341

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.322

Region-enriched R2: 4.527/0.00902

SLC24A3 1.76 - 0.793 - 0.967 - - Mlig455_010341 {REF} {Length: 5044} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=160.6]} {Human: ENSG00000185052, SLC24A3, solute carrier family 24 member 3, [Score=174, Expect=5e-45]; ENSG00000155886, SLC24A2, solute carrier family 24 member 2, [Score=172, Expect=2e-44]; ENSG00000140090, SLC24A4, solute carrier family 24 member 4, [Score=172, Expect=8e-45]} {Mouse: ENSMUSG00000041771, Slc24a4, solute carrier family 24 (sodium/potassium/calcium exchanger), member 4, [Score=172, Expect=5e-45]; ENSMUSG00000063873, Slc24a3, solute carrier family 24 (sodium/potassium/calcium exchanger), member 3, [Score=171, Expect=1e-44]; ENSMUSG00000037996, Slc24a2, solute carrier family 24 (sodium/potassium/calcium exchanger), member 2, [Score=170, Expect=6e-44]} {Dmel: FBgn0028704, Nckx30C, [Score=163, Expect=3e-41]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=143, Expect=2e-35]} {Smed: dd_Smed_v6_9736_0_1, dd_Smed_v6_9736_0_1, [Score=310, Expect=2e-95]} {RNA1509_40109} {RNA1310_8845} {RNA815_2786.1}
80. MligTC455_27522 684 14.26 Mlig455_050093

Neo: -

Age: logFC(26M/2M)=5.091

1.756 - - - 0.981 0.775 - Mlig455_050093 {REF} {Length: 1057} {NoTransDecoderORF} {RNA1509_37967} {RNA1310_6299.1} {RNA815_1994.1}
81. MligTC455_27521 681 14.19 Mlig455_050046

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.667

Region-enriched R2: 1.375/0.04610

ABCG2 1.752 - - - 0.981 0.771 - Mlig455_050046 {REF} {Length: 3109} {Pfam: ABC-2 type transporter [PF01061.26, score=96.6]; ABC transporter [PF00005.29, score=96.0]; ABC-2 type transporter [PF19055.2, score=48.9]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=25.0]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=248, Expect=2e-72]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=249, Expect=4e-73]} {Dmel: FBgn0020445, E23, Early gene at 23, [RH, Score=389, Expect=3e-122]} {Celegans: WBGene00015479, wht-1, ABC transporter ATP-binding protein/permease wht-1, [Score=220, Expect=4e-63]} {Smed: dd_Smed_v6_4081_0_1, dd_Smed_v6_4081_0_1, [RH, Score=222, Expect=4e-63]} {RNA1509_19841, RNA1509_37967, RNA1509_52359} {RNA1310_6299.1, RNA1509_37967, RNA1509_52359} {RNA1509_37967, RNA1509_52359, RNA815_1994.1}
82. MligTC455_29929 164 3.41 Mlig455_030237, Mlig455_068015

Neo: -

Age: -

Region-enriched R2: 4.901/0.00350

SIX6 1.752 - 0.787 - 0.965 - -

Mlig455_030237 {REF} {Length: 2545} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.1]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=8e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=6e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=9e-93]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=2e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=2e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}

Mlig455_068015 {REF} {Length: 2713} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.2]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=7e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=5e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=1e-92]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=1e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=1e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}
83. MligTC455_47905 56 1.16 Mlig455_037694

Neo: -

Age: -

1.741 - - - 0.954 0.787 - Mlig455_037694 {REF} {Length: 2503} {RNA1310_36768.1} {RNA815_27683}
84. MligTC455_50704 36 0.74 Mlig455_007321, Mlig455_068329

Neo: -

Age: -

1.727 - 0.777 - 0.950 - -

Mlig455_007321 {REF} {Length: 1784} {RNA815_63232}

Mlig455_068329 {REF} {Length: 1748} {RNA815_63232}
85. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 1.722 - 0.759 - 0.963 - - Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
86. MligTC455_53489 93 1.93 Mlig455_055317

Neo: -

Age: Down-Up-Down

FBXL7 1.714 - - - 0.954 0.760 - Mlig455_055317 {REF} {Length: 3638} {Pfam: Leucine Rich repeat [PF13516.8, score=53.5]; F-box-like [PF12937.9, score=45.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=31.8]; F-box domain [PF00646.35, score=28.5]} {Human: ENSG00000183580, FBXL7, F-box and leucine rich repeat protein 7, [RH, Score=176, Expect=2e-47]} {Mouse: ENSMUSG00000043556, Fbxl7, F-box and leucine-rich repeat protein 7, [RH, Score=177, Expect=4e-48]} {Dmel: FBgn0038385, Fbxl7, F-box and leucine-rich repeat protein 7, [RH, Score=176, Expect=2e-46]} {Celegans: WBGene00015350, fbxl-1, Uncharacterized F-box/LRR-repeat protein C02F5.7, [Score=112, Expect=3e-26]} {Smed: dd_Smed_v6_10647_0_1, dd_Smed_v6_10647_0_1, [RH, Score=114, Expect=2e-26]} {RNA1310_5789.1} {RNA815_11910}
87. MligTC455_44176 89 1.85 Mlig455_022911

Neo: -

Age: -

TNKS 1.71 - - - 0.951 0.759 - Mlig455_022911 {REF} {Length: 1883} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=67.0]; Ankyrin repeats (3 copies) [PF12796.9, score=64.6]; Ankyrin repeats (many copies) [PF13857.8, score=59.2]; Ankyrin repeat [PF13606.8, score=50.9]; Ankyrin repeat [PF00023.32, score=50.1]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=57.8, Expect=3e-08]; ENSG00000285372, AC270292.3, tankyrase, [Score=56.6, Expect=7e-08]; ENSG00000236759, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000238134, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000204371, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000206376, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000227333, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000232045, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000224143, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000029534, ANK1, ankyrin 1, [Score=55.5, Expect=2e-07]} {Mouse: ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=57.8, Expect=1e-08]; ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=57.8, Expect=1e-08]; ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=57.8, Expect=2e-08]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=57.4, Expect=1e-08]; ENSMUSG00000013787, Ehmt2, euchromatic histone lysine N-methyltransferase 2, [Score=55.8, Expect=9e-08]; ENSMUSG00000063932, Poteg, POTE ankyrin domain family, member G, [Score=55.5, Expect=8e-08]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=55.5, Expect=1e-07]; ENSMUSG00000110591, Gm31371, predicted gene, 31371, [Score=55.5, Expect=4e-08]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=55.1, Expect=8e-08]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=55.1, Expect=8e-08]} {Dmel: FBgn0040752, Prosap, [Score=58.9, Expect=6e-09]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=53.5, Expect=2e-07]} {Smed: dd_Smed_v6_2072_0_22, dd_Smed_v6_2072_0_22, [Score=62.0, Expect=4e-10]} {RNA1509_39040} {RNA1310_19494} {RNA815_14632}
88. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

1.709 - 0.756 - 0.953 - - Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
89. MligTC455_16096 69 1.44 Mlig455_059809

Neo: -

Age: -

ANGPTL1 1.706 - - - 0.974 0.732 - Mlig455_059809 {REF} {Length: 1391} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=117.9]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=109, Expect=1e-26]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=106, Expect=2e-25]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=110, Expect=3e-27]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=105, Expect=2e-25]} {Dmel: FBgn0003326, sca, scabrous, [Score=91.3, Expect=3e-20]} {Celegans: WBGene00017013, ensh-1, [Score=61.2, Expect=1e-10]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=77.8, Expect=5e-16]} {RNA1509_28467} {RNA1310_47262} {RNA815_18070.1}
90. MligTC455_32644 41 0.86 Mlig455_043770, Mlig455_043786

Neo: -

Age: -

Region-enriched R2: 6.705/0.00336

1.691 - 0.733 - 0.958 - -

Mlig455_043770 {REF} {Length: 1011} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.8, Expect=3e-11]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}

Mlig455_043786 {REF} {Length: 1348} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
91. MligTC455_11493 29 0.61 Mlig455_002993

Neo: -

Age: -

HS3ST5 1.689 - - 0.723 0.966 - - Mlig455_002993 {REF} {Length: 2472} {Pfam: Sulfotransferase domain [PF00685.29, score=91.7]; Sulfotransferase family [PF13469.8, score=45.8]} {Human: ENSG00000249853, HS3ST5, heparan sulfate-glucosamine 3-sulfotransferase 5, [RH, Score=256, Expect=8e-83]} {Mouse: ENSMUSG00000044499, Hs3st5, heparan sulfate (glucosamine) 3-O-sulfotransferase 5, [RH, Score=258, Expect=1e-83]} {Dmel: FBgn0031005, Hs3st-B, Heparan sulfate 3-O sulfotransferase-B, [Score=205, Expect=7e-63]} {Celegans: WBGene00044303, hst-3.2, Heparan SulphoTransferase, [Score=215, Expect=8e-68]} {Smed: dd_Smed_v6_81402_0_1, dd_Smed_v6_81402_0_1, [Score=123, Expect=6e-34]} {RNA1310_37118} {RNA815_58609}
92. MligTC455_24094 881 18.35 Mlig455_013384

Neo: -

Age: logFC(26M/2M)=-0.379

FAT4 1.686 - - - 0.950 - 0.736 Mlig455_013384 {REF} {Length: 10082} {Pfam: Cadherin domain [PF00028.19, score=873.7]; Cadherin-like [PF16184.7, score=117.8]; Cadherin-like [PF08266.14, score=37.7]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=614, Expect=3e-176]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=610, Expect=3e-175]} {Dmel: FBgn0001075, ft, fat, [Score=483, Expect=2e-136]} {Celegans: WBGene00000396, cdh-4, Cadherin-4, [Score=265, Expect=3e-70]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=296, Expect=8e-80]} {RNA1509_18808, RNA1509_37372, RNA1509_41735, RNA1509_43667} {RNA1310_91.1, RNA1509_37372, RNA1509_41735, RNA1509_43667} {RNA1509_37372, RNA1509_41735, RNA1509_43667, RNA815_45.1}
93. MligTC455_22688 18 0.37 Mlig455_030413

Neo: -

Age: -

GRIK3 1.68 - - 0.720 0.960 - - Mlig455_030413 {REF} {Length: 3851} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=76.0]; Ligand-gated ion channel [PF00060.28, score=51.9]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=45.7]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=158, Expect=1e-40]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=153, Expect=7e-39]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=149, Expect=7e-38]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=149, Expect=6e-38]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=148, Expect=2e-37]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=142, Expect=1e-35]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=132, Expect=1e-32]} {Smed: dd_Smed_v6_4267_0_3, dd_Smed_v6_4267_0_3, [Score=149, Expect=5e-38]} {RNA1310_20394.1} {RNA815_45848}
94. MligTC455_35701 66 1.37 Mlig455_010067, Mlig455_063254, Mlig455_063279

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.716/0.02468

1.668 - - - 0.952 0.716 -

Mlig455_010067 {REF} {Length: 2624} {Pfam: Polycystin cation channel [PF08016.14, score=46.7]} {RNA1310_62521}

Mlig455_063254 {REF} {Length: 2738} {Pfam: Polycystin cation channel [PF08016.14, score=43.3]; Lipopolysaccharide assembly protein A domain [PF06305.13, score=18.4]} {RNA1509_7418} {RNA1310_62521} {RNA815_3659}

Mlig455_063279 {REF} {Length: 2677} {Pfam: Polycystin cation channel [PF08016.14, score=46.0]} {RNA1310_62521}
95. MligTC455_50069 6 0.13 Mlig455_043232

Neo: -

Age: -

0.984 - - - 0.984 - - Mlig455_043232 {REF} {Length: 2180} {RNA1509_46424} {RNA1310_8850} {RNA815_3382.1}
96. MligTC455_15598 45 0.94 Mlig455_021461

Neo: -

Age: Down-Up-Up

0.978 - - - 0.978 - - Mlig455_021461 {REF} {Length: 2020} {RNA1310_35982.1} {RNA815_27626}
97. MligTC455_23617 4708 98.09 Mlig455_008651, Mlig455_069417

Neo: -

Age: -

C5orf49 0.973 - - - 0.973 - -

Mlig455_008651 {REF} {Length: 762} {Pfam: Domain of unknown function (DUF4541) [PF15074.8, score=117.5]} {Human: ENSG00000215217, C5orf49, chromosome 5 open reading frame 49, [RH, Score=97.4, Expect=9e-26]} {Mouse: ENSMUSG00000021534, 1700001L19Rik, RIKEN cDNA 1700001L19 gene, [RH, Score=103, Expect=5e-28]} {Smed: dd_Smed_v6_6211_0_1, dd_Smed_v6_6211_0_1, [RH, Score=136, Expect=1e-41]} {RNA1509_14600} {RNA1310_49397} {RNA815_23943.1}

Mlig455_069417 {REF} {Length: 762} {Pfam: Domain of unknown function (DUF4541) [PF15074.8, score=117.5]} {Human: ENSG00000215217, C5orf49, chromosome 5 open reading frame 49, [RH, Score=97.4, Expect=9e-26]} {Mouse: ENSMUSG00000021534, 1700001L19Rik, RIKEN cDNA 1700001L19 gene, [RH, Score=103, Expect=5e-28]} {Smed: dd_Smed_v6_6211_0_1, dd_Smed_v6_6211_0_1, [RH, Score=136, Expect=1e-41]} {RNA1509_14600, RNA1509_24973} {RNA1310_49397, RNA1509_14600, RNA1509_24973} {RNA1509_14600, RNA1509_24973, RNA815_23943.1}
98. MligTC455_09688 16 0.32 Mlig455_020078

Neo: -

Age: -

Region-enriched R5: 3.740/0.03280

0.972 - - - 0.972 - - Mlig455_020078 {REF} {Length: 803} {Pfam: WSC domain [PF01822.21, score=60.8]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=56.6, Expect=2e-09]} {RNA1509_53783} {RNA1310_40622} {RNA815_30345}
99. MligTC455_31663 23 0.48 Mlig455_013845

Neo: -

Age: -

0.972 - - - 0.972 - - Mlig455_013845 {REF} {Length: 1056} {RNA1310_32319} {RNA815_18072}
100. MligTC455_44922 15 0.31 Mlig455_040611

Neo: -

Age: -

AC254952.1 0.972 - - - 0.972 - - Mlig455_040611 {REF} {Length: 1658} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=86.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=85.3]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=1e-40]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=2e-40]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=2e-40]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=147, Expect=9e-39]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=129, Expect=1e-32]} {Celegans: WBGene00001133, eat-2, Neuronal acetylcholine receptor subunit eat-2, [Score=136, Expect=2e-35]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=136, Expect=2e-35]} {RNA1310_45581} {RNA815_21574}

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