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Results for MligTC455_27392

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_27392 69 1.44 Mlig455_025611

Neo: -

Age: -

Mlig455_025611 {REF} {Length: 1130} {NoTransDecoderORF} {RNA1509_53194} {RNA1310_47725} {RNA815_22886.1}

Cumulative graph for MligTC455_27392

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.555 1.531 1.00000 1.00000
RegionR2 1.128 1.531 0.38984 0.78467
RegionR3 -1.269 1.531 0.95592 1.00000
RegionR4 2.246 1.531 0.15686 0.41159
RegionR5 -0.694 1.531 0.90416 1.00000
RegionR6 0.978 1.531 0.39248 0.96689
RegionR7 -3.487 1.531 1.00000 1.00000
RegionR8 1.652 1.531 0.33864 0.97256

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.035 1.531 0.99997 1.00000
RegenerationR2 0.725 1.531 0.31710 0.75561
RegenerationR3 1.945 1.531 0.14593 0.57312
RegenerationR4 -0.079 1.531 0.94996 1.00000
RegenerationR5 1.762 1.531 0.12881 0.53383
RegenerationR6 0.618 1.531 0.57644 0.85544
RegenerationBL 2.479 1.531 0.10642 0.38518
RegenerationTP 2.39 1.531 0.21819 0.66171


Genes with expression patterns similar to MligTC455_27392

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_27392 69 1.44 Mlig455_025611

Neo: -

Age: -

4 - - 1.000 1.000 1.000 1.000 Mlig455_025611 {REF} {Length: 1130} {NoTransDecoderORF} {RNA1509_53194} {RNA1310_47725} {RNA815_22886.1}
2. MligTC455_22446 195 4.05 Mlig455_002759, Mlig455_063362

Neo: -

Age: -

Region-enriched R2: 4.960/0.00023

SLC6A3 2.669 - - 0.958 0.974 0.737 -

Mlig455_002759 {REF} {Length: 4906} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=606.3]; Rhomboid family [PF01694.24, score=73.2]} {Human: ENSG00000276996, SLC6A3, solute carrier family 6 member 3, [Score=541, Expect=9e-179]; ENSG00000142319, SLC6A3, solute carrier family 6 member 3, [Score=541, Expect=9e-179]; ENSG00000103546, SLC6A2, solute carrier family 6 member 2, [Score=540, Expect=3e-178]} {Mouse: ENSMUSG00000055368, Slc6a2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, [Score=552, Expect=0.0]; ENSMUSG00000021609, Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, [Score=545, Expect=3e-180]} {Dmel: FBgn0034136, DAT, Dopamine transporter, [Score=498, Expect=2e-162]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=446, Expect=9e-143]} {Smed: dd_Smed_v6_22486_0_1, dd_Smed_v6_22486_0_1, [RH, Score=605, Expect=0.0]} {RNA1509_46048} {RNA1310_21784} {RNA815_8613}

Mlig455_063362 {REF} {Length: 2875} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=603.8]} {Human: ENSG00000276996, SLC6A3, solute carrier family 6 member 3, [Score=543, Expect=0.0]; ENSG00000142319, SLC6A3, solute carrier family 6 member 3, [Score=543, Expect=0.0]; ENSG00000103546, SLC6A2, solute carrier family 6 member 2, [Score=540, Expect=0.0]} {Mouse: ENSMUSG00000055368, Slc6a2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, [Score=551, Expect=0.0]; ENSMUSG00000021609, Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, [Score=549, Expect=0.0]} {Dmel: FBgn0034136, DAT, Dopamine transporter, [Score=494, Expect=4e-167]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=444, Expect=7e-148]} {Smed: dd_Smed_v6_22486_0_1, dd_Smed_v6_22486_0_1, [RH, Score=599, Expect=0.0]} {RNA1509_46048} {RNA1310_21784} {RNA815_8613}
3. MligTC455_13468 36 0.75 Mlig455_044410, Mlig455_044445

Neo: -

Age: -

2.646 - - 0.864 0.955 0.827 -

Mlig455_044410 {REF} {Length: 1049} {Pfam: Dynein light chain type 1 [PF01221.20, score=56.6]; EF-hand domain pair [PF13499.8, score=29.7]; EF hand [PF00036.34, score=25.9]; EF-hand domain [PF13405.8, score=20.6]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [Score=130, Expect=9e-39]} {RNA1310_56608} {RNA815_53279}

Mlig455_044445 {REF} {Length: 1016} {Pfam: Dynein light chain type 1 [PF01221.20, score=56.6]; EF-hand domain pair [PF13499.8, score=29.7]; EF hand [PF00036.34, score=25.9]; EF-hand domain [PF13405.8, score=20.6]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [Score=130, Expect=9e-39]} {RNA1310_56608} {RNA815_53279}
4. MligTC455_19455 23 0.48 Mlig455_059587

Neo: -

Age: Up-Down-Down

2.64 - - 0.920 0.964 0.756 - Mlig455_059587 {REF} {Length: 1356} {Pfam: FAM216B protein family [PF15107.8, score=21.6]} {RNA1310_31687} {RNA815_40824}
5. MligTC455_53321 59 1.24 Mlig455_046286

Neo: -

Age: -

Region-enriched R4: 6.404/0.01336

2.621 - - 0.876 0.959 0.786 - Mlig455_046286 {REF} {Length: 1085} {RNA1509_49086} {RNA1310_87385, RNA1509_49086}
6. MligTC455_44442 1201 25.03 Mlig455_003131

Neo: -

Age: logFC(26M/2M)=-0.363

2.596 - - 0.828 0.962 0.806 - Mlig455_003131 {REF} {Length: 1831} {RNA1509_26624, RNA1509_27545, RNA1509_31759, RNA1509_3524, RNA1509_42258, RNA1509_44854} {RNA1310_10649.1, RNA1509_26624, RNA1509_27545, RNA1509_31759, RNA1509_42258, RNA1509_44854} {RNA1509_26624, RNA1509_27545, RNA1509_31759, RNA1509_42258, RNA1509_44854, RNA815_4791.2}
7. MligTC455_32942 127 2.65 Mlig455_013414

Neo: -

Age: -

GRID2IP 2.587 - - 0.879 0.973 0.735 - Mlig455_013414 {REF} {Length: 3335} {Pfam: PDZ domain [PF00595.26, score=43.7]; PDZ domain [PF17820.3, score=43.0]; C2 domain [PF00168.32, score=29.7]; PDZ domain [PF13180.8, score=28.8]; Tricorn protease PDZ domain [PF14685.8, score=22.3]; Short myomegalin-like EB1 binding proteins, N-terminal domain [PF18615.3, score=19.3]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=19.2]; DDHD domain [PF02862.19, score=18.8]} {Human: ENSG00000215045, GRID2IP, Grid2 interacting protein, [Score=50.8, Expect=7e-06]; ENSG00000159788, RGS12, regulator of G protein signaling 12, [Score=50.4, Expect=8e-06]} {Mouse: ENSMUSG00000029101, Rgs12, regulator of G-protein signaling 12, [Score=50.1, Expect=9e-06]} {Dmel: FBgn0020278, loco, locomotion defects, [Score=58.5, Expect=2e-08]} {Smed: dd_Smed_v6_17732_0_1, dd_Smed_v6_17732_0_1, [Score=86.7, Expect=1e-17]} {RNA1310_13395.2} {RNA815_18584}
8. MligTC455_26600 111 2.32 Mlig455_000691

Neo: -

Age: logFC(26M/2M)=-0.305

Region-enriched R2: 4.160/0.03510

2.586 - - 0.831 0.960 0.795 - Mlig455_000691 {REF} {Length: 6281} {Smed: dd_Smed_v6_17076_0_1, dd_Smed_v6_17076_0_1, [RH, Score=214, Expect=1e-56]} {RNA1509_20580} {RNA1310_21461} {RNA815_12493}
9. MligTC455_10068 96 1.99 Mlig455_066097

Neo: -

Age: -

2.584 - - 0.828 0.960 0.796 - Mlig455_066097 {REF} {Length: 776} {Pfam: EF hand [PF00036.34, score=46.7]; EF-hand domain pair [PF13499.8, score=41.3]; EF-hand domain [PF13405.8, score=39.9]; EF hand [PF13202.8, score=32.3]; EF-hand domain pair [PF13833.8, score=27.2]} {Celegans: WBGene00269435, T27C10.9, [Score=43.5, Expect=7e-06]} {Smed: dd_Smed_v6_23220_0_1, dd_Smed_v6_23220_0_1, [Score=46.2, Expect=9e-07]} {RNA1310_43617} {RNA815_21313}
10. MligTC455_12801 45 0.94 Mlig455_014787, Mlig455_014844

Neo: -

Age: -

2.555 - - 0.854 0.959 0.742 -

Mlig455_014787 {REF} {Length: 900} {RNA1310_52577} {RNA815_26355}

Mlig455_014844 {REF} {Length: 1217} {RNA1310_52577} {RNA815_26355}
11. MligTC455_44789 48 0.99 Mlig455_018729, Mlig455_018919

Neo: -

Age: -

CALML3 2.555 - - 0.782 0.960 0.813 -

Mlig455_018729 {REF} {Length: 803} {Pfam: EF hand [PF00036.34, score=83.6]; EF-hand domain pair [PF13499.8, score=76.3]; EF-hand domain pair [PF13833.8, score=67.5]; EF-hand domain [PF13405.8, score=67.1]; EF hand [PF13202.8, score=48.4]; EF-hand domain [PF14658.8, score=27.2]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=20.1]; Family of unknown function (DUF5580) [PF17743.3, score=18.7]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=90.5, Expect=2e-23]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=89.7, Expect=2e-23]} {Dmel: FBgn0033238, azot, ahuizotl, [Score=84.0, Expect=3e-21]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=75.5, Expect=5e-18]} {Smed: dd_Smed_v6_11942_0_1, dd_Smed_v6_11942_0_1, [Score=77.4, Expect=9e-19]} {RNA1509_9648} {RNA1310_21302} {RNA815_28645}

Mlig455_018919 {REF} {Length: 804} {Pfam: EF hand [PF00036.34, score=83.6]; EF-hand domain pair [PF13499.8, score=76.3]; EF-hand domain pair [PF13833.8, score=67.5]; EF-hand domain [PF13405.8, score=67.1]; EF hand [PF13202.8, score=48.4]; EF-hand domain [PF14658.8, score=27.2]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=20.1]; Family of unknown function (DUF5580) [PF17743.3, score=18.7]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=90.5, Expect=2e-23]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=89.7, Expect=2e-23]} {Dmel: FBgn0033238, azot, ahuizotl, [Score=84.0, Expect=3e-21]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=75.5, Expect=5e-18]} {Smed: dd_Smed_v6_11942_0_1, dd_Smed_v6_11942_0_1, [Score=77.4, Expect=9e-19]} {RNA1509_9648} {RNA1310_21302} {RNA815_28645}
12. MligTC455_41318 183 3.81 Mlig455_061686

Neo: -

Age: -

2.524 - - 0.723 0.969 0.832 - Mlig455_061686 {REF} {Length: 788} {TRANSSPLICED} {RNA1509_31046} {RNA1310_41579} {RNA815_19702}
13. MligTC455_25464 185 3.85 Mlig455_001339

Neo: -

Age: -

Region-enriched R2: 4.725/0.00025

2.492 - - 0.818 0.952 0.722 - Mlig455_001339 {REF} {Length: 1386} {RNA1509_58508} {RNA1310_32754, RNA1509_58508} {RNA1509_58508, RNA815_47065}
14. MligTC455_50589 29 0.61 Mlig455_010626, Mlig455_010716

Neo: -

Age: Down-Up-Down

2.469 - - 0.755 0.959 0.755 -

Mlig455_010626 {REF} {Length: 2021} {Pfam: Tctex-1 family [PF03645.15, score=27.5]} {RNA1310_36440}

Mlig455_010716 {REF} {Length: 2038} {Pfam: Tctex-1 family [PF03645.15, score=27.2]} {RNA1310_36440}
15. MligTC455_26253 375 7.81 Mlig455_009976

Neo: -

Age: -

FZD5 2.462 - - 0.759 0.958 0.745 - Mlig455_009976 {REF} {Length: 4082} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=407.2]; Fz domain [PF01392.24, score=99.7]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [RH, Score=605, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=607, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [RH, Score=402, Expect=2e-130]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [RH, Score=417, Expect=8e-139]} {Smed: dd_Smed_v6_11823_0_1, dd_Smed_v6_11823_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_25697, RNA1509_59712} {RNA1310_9946, RNA1509_25697} {RNA1509_25697, RNA815_7287}
16. MligTC455_33812 919 19.14 Mlig455_051682

Neo: -

Age: -

Region-enriched R2: 3.553/0.00065

MOXD1 2.461 - - 0.780 0.955 0.726 - Mlig455_051682 {REF} {Length: 2654} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=93.8]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=68.4]; Proline-rich membrane anchor 1 [PF16101.7, score=18.9]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=120, Expect=2e-28]; ENSG00000123454, DBH, dopamine beta-hydroxylase, [Score=117, Expect=2e-27]} {Mouse: ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=135, Expect=1e-33]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=129, Expect=8e-32]} {Celegans: WBGene00006541, tbh-1, Tyramine beta-hydroxylase, [Score=139, Expect=2e-35]} {Smed: dd_Smed_v6_42610_0_1, dd_Smed_v6_42610_0_1, [Score=119, Expect=1e-29]} {RNA1509_127, RNA1509_19917, RNA1509_32862, RNA1509_35753, RNA1509_41801} {RNA1310_9934.2, RNA1509_19917, RNA1509_32862, RNA1509_35753, RNA1509_41801} {RNA1509_19917, RNA1509_32862, RNA1509_35753, RNA1509_41801, RNA815_4383.1}
17. MligTC455_15367 110 2.3 Mlig455_067477, Mlig455_067486

Neo: -

Age: -

TCF23 2.439 - - 0.715 0.959 0.765 -

Mlig455_067477 {REF} {Length: 756} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=41.4]} {Human: ENSG00000163792, TCF23, transcription factor 23, [RH, Score=88.2, Expect=2e-22]} {Mouse: ENSMUSG00000006642, Tcf23, transcription factor 23, [RH, Score=85.9, Expect=1e-21]} {Dmel: FBgn0011277, HLH4C, Helix loop helix protein 4C, [Score=49.3, Expect=3e-08]} {Celegans: WBGene00001959, hlh-15, Helix Loop Helix, [Score=47.0, Expect=5e-08]} {Smed: dd_Smed_v6_16070_0_1, dd_Smed_v6_16070_0_1, [Score=52.8, Expect=1e-09]} {RNA1310_4676} {RNA815_18327.1}

Mlig455_067486 {REF} {Length: 273} {NoTransDecoderORF} {RNA1310_4676} {RNA815_18327.2}
18. MligTC455_16292 176 3.67 Mlig455_029213

Neo: Irradiation

Age: Up-Down-Down, logFC(26M/2M)=-0.543

Region-enriched R2: 3.505/0.04173

PRKAR2B 2.436 - - 0.729 0.959 0.748 - Mlig455_029213 {REF} {Length: 1890} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=75.9]} {Human: ENSG00000005249, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, [Score=51.6, Expect=1e-06]; ENSG00000284096, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, [Score=51.6, Expect=1e-06]} {Mouse: ENSMUSG00000002997, Prkar2b, protein kinase, cAMP dependent regulatory, type II beta, [Score=51.2, Expect=1e-06]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [Score=52.8, Expect=2e-07]} {Smed: dd_Smed_v6_14355_0_1, dd_Smed_v6_14355_0_1, [Score=104, Expect=2e-24]} {RNA1509_14151} {RNA1310_17181} {RNA815_7262}
19. MligTC455_50344 24 0.51 Mlig455_054355

Neo: -

Age: -

2.418 - - 0.721 0.959 0.738 - Mlig455_054355 {REF} {Length: 1376} {RNA1310_56750}
20. MligTC455_28267 180 3.74 Mlig455_008230

Neo: -

Age: -

2.416 - - 0.962 - 0.752 0.702 Mlig455_008230 {REF} {Length: 912} {Pfam: Integrase core domain [PF00665.28, score=28.8]} {Smed: dd_Smed_v6_11155_0_6, dd_Smed_v6_11155_0_6, [Score=47.0, Expect=1e-06]} {RNA1509_21400} {RNA1310_576.1} {RNA815_2733.1}
21. MligTC455_05192 79 1.65 Mlig455_011809

Neo: -

Age: logFC(26M/2M)=-0.672

BCHE 2.407 - - - 0.959 0.746 0.702 Mlig455_011809 {REF} {Length: 3543} {Pfam: Carboxylesterase family [PF00135.30, score=386.4]; alpha/beta hydrolase fold [PF07859.15, score=35.9]} {Human: ENSG00000114200, BCHE, butyrylcholinesterase, [Score=294, Expect=1e-91]; ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=290, Expect=3e-89]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [Score=305, Expect=1e-95]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=221, Expect=2e-63]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=308, Expect=1e-96]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=365, Expect=2e-118]} {RNA1509_5880} {RNA1310_9146.1} {RNA815_3169.2}
22. MligTC455_36729 109 2.26 Mlig455_031568

Neo: -

Age: -

Region-enriched R2: 4.085/0.04774

2.405 - - 0.703 0.955 0.747 - Mlig455_031568 {REF} {Length: 4709} {RNA1310_20703.1} {RNA815_12377}
23. MligTC455_36507 1422 29.63 Mlig455_038156, Mlig455_038261

Neo: -

Age: logFC(26M/2M)=-0.241

DNAI2 2.388 - - 0.714 0.955 0.719 -

Mlig455_038156 {REF} {Length: 2699} {TRANSSPLICED} {Human: ENSG00000171595, DNAI2, dynein axonemal intermediate chain 2, [Score=534, Expect=0.0]} {Mouse: ENSMUSG00000034706, Dnaic2, dynein, axonemal, intermediate chain 2, [Score=513, Expect=1e-178]} {Dmel: FBgn0036195, Dnai2, dynein, axonemal, intermediate chain 2, [Score=386, Expect=4e-129]} {Smed: dd_Smed_v6_2644_0_1, dd_Smed_v6_2644_0_1, [Score=612, Expect=0.0]} {RNA1509_8245} {RNA1310_9583.1} {RNA815_3264}

Mlig455_038261 {REF} {Length: 2387} {TRANSSPLICED} {Human: ENSG00000171595, DNAI2, dynein axonemal intermediate chain 2, [RH, Score=756, Expect=0.0]} {Mouse: ENSMUSG00000034706, Dnaic2, dynein, axonemal, intermediate chain 2, [RH, Score=740, Expect=0.0]} {Dmel: FBgn0036195, Dnai2, dynein, axonemal, intermediate chain 2, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_2644_0_1, dd_Smed_v6_2644_0_1, [RH, Score=867, Expect=0.0]} {RNA1509_8245} {RNA1310_9583.1} {RNA815_3264}
24. MligTC455_18996 34 0.71 Mlig455_032938

Neo: -

Age: -

1.909 - - 0.958 0.951 - - Mlig455_032938 {REF} {Length: 1648} {Pfam: Transposase DDE domain [PF01609.23, score=18.8]} {RNA1509_39626} {RNA1310_29809} {RNA815_13636}
25. MligTC455_17084 3912 81.51 Mlig455_013175, Mlig455_045995

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.971

CA12 1.895 - - 0.924 0.971 - -

Mlig455_013175 {REF} {Length: 1735} {Pfam: Eukaryotic-type carbonic anhydrase [PF00194.23, score=186.3]} {Human: ENSG00000074410, CA12, carbonic anhydrase 12, [Score=126, Expect=5e-33]; ENSG00000168748, CA7, carbonic anhydrase 7, [Score=121, Expect=7e-32]} {Mouse: ENSMUSG00000032373, Car12, carbonic anhydrase 12, [Score=133, Expect=1e-35]} {Dmel: FBgn0027844, CAH1, Carbonic anhydrase 1, [Score=105, Expect=2e-26]} {Celegans: WBGene00000283, cah-5, Putative carbonic anhydrase 5, [Score=87.4, Expect=2e-19]} {Smed: dd_Smed_v6_11683_0_1, dd_Smed_v6_11683_0_1, [RH, Score=167, Expect=4e-49]} {RNA1509_10777, RNA1509_21098} {RNA1310_14884.1, RNA1509_10777} {RNA1509_10777, RNA815_8568.1}

Mlig455_045995 {REF} {Length: 1770} {Pfam: Eukaryotic-type carbonic anhydrase [PF00194.23, score=184.2]} {Human: ENSG00000074410, CA12, carbonic anhydrase 12, [Score=125, Expect=8e-33]; ENSG00000168748, CA7, carbonic anhydrase 7, [Score=121, Expect=6e-32]} {Mouse: ENSMUSG00000032373, Car12, carbonic anhydrase 12, [Score=132, Expect=2e-35]} {Dmel: FBgn0038956, CG5379, [Score=106, Expect=4e-26]} {Celegans: WBGene00000283, cah-5, Putative carbonic anhydrase 5, [Score=87.8, Expect=2e-19]} {Smed: dd_Smed_v6_11683_0_1, dd_Smed_v6_11683_0_1, [RH, Score=171, Expect=6e-51]} {RNA1509_10449, RNA1509_21098, RNA1509_31212, RNA1509_48169} {RNA1310_14884.1, RNA1509_10449, RNA1509_21098, RNA1509_31212, RNA1509_48169} {RNA1509_10449, RNA1509_21098, RNA1509_31212, RNA1509_48169, RNA815_8568.1}
26. MligTC455_12941 287 5.98 Mlig455_019071, Mlig455_064296, Mlig455_064333

Neo: -

Age: -

ZIC2, ZIC5 1.858 - - 0.893 0.965 - -

Mlig455_019071 {REF} {Length: 2056} {Pfam: Zinc-finger double domain [PF13465.8, score=59.0]; Zinc finger, C2H2 type [PF00096.28, score=57.3]; C2H2-type zinc finger [PF13894.8, score=25.8]} {Human: ENSG00000139800, ZIC5, Zic family member 5, [Score=245, Expect=1e-71]; ENSG00000043355, ZIC2, Zic family member 2, [Score=244, Expect=2e-72]; ENSG00000156925, ZIC3, Zic family member 3, [Score=240, Expect=1e-71]; ENSG00000174963, ZIC4, Zic family member 4, [Score=239, Expect=2e-72]; ENSG00000152977, ZIC1, Zic family member 1, [Score=239, Expect=1e-71]} {Mouse: ENSMUSG00000041703, Zic5, zinc finger protein of the cerebellum 5, [Score=249, Expect=2e-73]; ENSMUSG00000061524, Zic2, zinc finger protein of the cerebellum 2, [Score=244, Expect=1e-72]; ENSMUSG00000067860, Zic3, zinc finger protein of the cerebellum 3, [Score=240, Expect=8e-72]; ENSMUSG00000036972, Zic4, zinc finger protein of the cerebellum 4, [Score=240, Expect=2e-73]; ENSMUSG00000032368, Zic1, zinc finger protein of the cerebellum 1, [Score=240, Expect=6e-72]} {Dmel: FBgn0003002, opa, odd paired, [Score=235, Expect=1e-68]} {Celegans: WBGene00004335, ref-2, REgulator of Fusion, [Score=180, Expect=1e-51]} {Smed: dd_Smed_v6_15531_0_1, dd_Smed_v6_15531_0_1, [Score=253, Expect=6e-77]} {RNA1509_20828} {RNA1310_25086} {RNA815_49740}

Mlig455_064296 {REF} {Length: 2676} {Pfam: Zic proteins zinc finger domain [PF18366.3, score=75.7]; Zinc-finger double domain [PF13465.8, score=61.4]; Zinc finger, C2H2 type [PF00096.28, score=59.4]; C2H2-type zinc finger [PF13894.8, score=22.5]} {Human: ENSG00000043355, ZIC2, Zic family member 2, [RH, Score=286, Expect=5e-90]; ENSG00000152977, ZIC1, Zic family member 1, [RH, Score=285, Expect=2e-90]; ENSG00000156925, ZIC3, Zic family member 3, [RH, Score=282, Expect=4e-89]; ENSG00000139800, ZIC5, Zic family member 5, [RH, Score=278, Expect=3e-85]; ENSG00000174963, ZIC4, Zic family member 4, [RH, Score=277, Expect=3e-88]} {Mouse: ENSMUSG00000061524, Zic2, zinc finger protein of the cerebellum 2, [RH, Score=287, Expect=2e-90]; ENSMUSG00000036972, Zic4, zinc finger protein of the cerebellum 4, [RH, Score=287, Expect=7e-93]; ENSMUSG00000032368, Zic1, zinc finger protein of the cerebellum 1, [RH, Score=285, Expect=1e-90]; ENSMUSG00000041703, Zic5, zinc finger protein of the cerebellum 5, [RH, Score=284, Expect=4e-88]; ENSMUSG00000067860, Zic3, zinc finger protein of the cerebellum 3, [RH, Score=283, Expect=9e-90]} {Dmel: FBgn0003002, opa, odd paired, [RH, Score=286, Expect=2e-89]} {Celegans: WBGene00004335, ref-2, REgulator of Fusion, [RH, Score=195, Expect=6e-58]} {Smed: dd_Smed_v6_15531_0_1, dd_Smed_v6_15531_0_1, [RH, Score=305, Expect=1e-98]} {RNA1509_20828} {RNA1310_25086} {RNA815_49740}

Mlig455_064333 {REF} {Length: 2303} {Pfam: Zic proteins zinc finger domain [PF18366.3, score=75.6]; Zinc-finger double domain [PF13465.8, score=61.3]; Zinc finger, C2H2 type [PF00096.28, score=58.7]; C2H2-type zinc finger [PF13894.8, score=21.1]} {Human: ENSG00000043355, ZIC2, Zic family member 2, [RH, Score=285, Expect=1e-89]; ENSG00000152977, ZIC1, Zic family member 1, [RH, Score=284, Expect=5e-90]; ENSG00000156925, ZIC3, Zic family member 3, [RH, Score=281, Expect=1e-88]; ENSG00000139800, ZIC5, Zic family member 5, [RH, Score=277, Expect=5e-85]; ENSG00000174963, ZIC4, Zic family member 4, [RH, Score=275, Expect=9e-88]} {Mouse: ENSMUSG00000061524, Zic2, zinc finger protein of the cerebellum 2, [RH, Score=286, Expect=7e-90]; ENSMUSG00000036972, Zic4, zinc finger protein of the cerebellum 4, [RH, Score=286, Expect=2e-92]; ENSMUSG00000032368, Zic1, zinc finger protein of the cerebellum 1, [RH, Score=284, Expect=3e-90]; ENSMUSG00000041703, Zic5, zinc finger protein of the cerebellum 5, [RH, Score=283, Expect=6e-88]; ENSMUSG00000067860, Zic3, zinc finger protein of the cerebellum 3, [RH, Score=282, Expect=2e-89]} {Dmel: FBgn0003002, opa, odd paired, [RH, Score=286, Expect=4e-89]} {Celegans: WBGene00004335, ref-2, REgulator of Fusion, [RH, Score=194, Expect=7e-58]} {Smed: dd_Smed_v6_15531_0_1, dd_Smed_v6_15531_0_1, [RH, Score=303, Expect=1e-97]} {RNA1509_20828} {RNA1310_25086} {RNA815_49740}
27. MligTC455_54051 43 0.9 Mlig455_045427

Neo: -

Age: -

Region-enriched R4: 5.401/0.01332

1.851 - - 0.952 0.899 - - Mlig455_045427 {REF} {Length: 3132} {TRANSSPLICED} {Pfam: TIR domain [PF13676.8, score=27.1]} {Smed: dd_Smed_v6_5672_1_1, dd_Smed_v6_5672_1_1, [Score=54.7, Expect=1e-07]} {RNA1509_45164} {RNA1310_10761} {RNA815_16707}
28. MligTC455_13776 37 0.76 Mlig455_035202, Mlig455_035250

Neo: -

Age: -

1.821 - - 0.863 0.958 - -

Mlig455_035202 {REF} {Length: 706} {RNA1310_62209}

Mlig455_035250 {REF} {Length: 706} {RNA1310_62209}
29. MligTC455_38022 31 0.66 Mlig455_052112

Neo: -

Age: -

1.802 - - 0.970 - 0.832 - Mlig455_052112 {REF} {Length: 1091} {NoTransDecoderORF} {RNA1509_22316} {RNA1310_68525} {RNA815_47119}
30. MligTC455_28108 147 3.07 Mlig455_049966, Mlig455_051247

Neo: -

Age: -

1.79 - - 0.992 - 0.798 -

Mlig455_049966 {REF} {Length: 1643} {NoTransDecoderORF} {RNA1509_57004} {RNA1310_14078} {RNA815_15623}

Mlig455_051247 {REF} {Length: 862} {NoTransDecoderORF} {RNA1509_57004} {RNA1310_15891} {RNA815_15623}
31. MligTC455_41986 57 1.19 Mlig455_027306

Neo: -

Age: -

TCF23 1.784 - - - 0.960 0.824 - Mlig455_027306 {REF} {Length: 1046} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=41.9]} {Human: ENSG00000163792, TCF23, transcription factor 23, [RH, Score=86.3, Expect=5e-22]} {Mouse: ENSMUSG00000006642, Tcf23, transcription factor 23, [RH, Score=84.3, Expect=2e-21]} {Dmel: FBgn0011277, HLH4C, Helix loop helix protein 4C, [Score=48.1, Expect=4e-08]} {Celegans: WBGene00001959, hlh-15, Helix Loop Helix, [Score=45.8, Expect=7e-08]} {Smed: dd_Smed_v6_16070_0_1, dd_Smed_v6_16070_0_1, [Score=52.4, Expect=9e-10]} {RNA1310_4676} {RNA815_18327.1}
32. MligTC455_32312 65 1.36 Mlig455_026936, Mlig455_027086

Neo: -

Age: Up-Down-Down

Region-enriched R2: 9.552/0.00000

1.772 - - - 0.971 0.801 -

Mlig455_026936 {REF} {Length: 1813} {Pfam: PAN domain [PF00024.28, score=22.0]} {RNA1310_30037.2} {RNA815_37290}

Mlig455_027086 {REF} {Length: 7697} {Pfam: PAN domain [PF00024.28, score=21.9]} {RNA1509_4722} {RNA1310_655.1} {RNA815_786}
33. MligTC455_39179 44 0.91 Mlig455_052012

Neo: -

Age: Down-Up-Up

TCTE3 1.765 - - 0.813 0.952 - - Mlig455_052012 {REF} {Length: 1042} {Pfam: Tctex-1 family [PF03645.15, score=42.5]} {Human: ENSG00000184786, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=65.9, Expect=8e-13]; ENSG00000275368, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=65.9, Expect=8e-13]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [Score=61.6, Expect=1e-11]} {Smed: dd_Smed_v6_9036_0_1, dd_Smed_v6_9036_0_1, [Score=92.8, Expect=1e-23]} {RNA1509_34873} {RNA1310_34743} {RNA815_18661}
34. MligTC455_17065 107 2.23 Mlig455_020928

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.486

1.761 - - 0.789 0.972 - - Mlig455_020928 {REF} {Length: 968} {NoTransDecoderORF} {RNA1310_36631} {RNA815_25225}
35. MligTC455_37347 61 1.28 Mlig455_023488

Neo: -

Age: -

1.751 - - 0.951 - 0.800 - Mlig455_023488 {REF} {Length: 2074} {RNA1509_44081} {RNA1310_36129} {RNA815_2004}
36. MligTC455_24063 339 7.06 Mlig455_048182

Neo: -

Age: Down-Down-Up

DYNLL1 1.742 - - 0.782 0.960 - - Mlig455_048182 {REF} {Length: 1157} {Pfam: Dynein light chain type 1 [PF01221.20, score=64.3]; EF hand [PF13202.8, score=43.3]; EF hand [PF00036.34, score=35.7]; EF-hand domain pair [PF13499.8, score=35.5]; EF-hand domain [PF13405.8, score=29.0]} {Human: ENSG00000088986, DYNLL1, dynein light chain LC8-type 1, [Score=60.1, Expect=1e-11]; ENSG00000264364, DYNLL2, dynein light chain LC8-type 2, [Score=60.1, Expect=1e-11]} {Mouse: ENSMUSG00000009013, Dynll1, dynein light chain LC8-type 1, [Score=60.1, Expect=7e-12]; ENSMUSG00000020483, Dynll2, dynein light chain LC8-type 2, [Score=60.1, Expect=7e-12]; ENSMUSG00000064063, BC048507, cDNA sequence BC048507, [Score=58.9, Expect=2e-11]} {Dmel: FBgn0011760, ctp, cut up, [Score=57.0, Expect=7e-11]} {Celegans: WBGene00001005, dlc-1, Dynein light chain 1, cytoplasmic, [Score=57.0, Expect=5e-11]} {Smed: dd_Smed_v6_9661_0_1, dd_Smed_v6_9661_0_1, [RH, Score=153, Expect=2e-47]} {RNA1509_6272} {RNA1310_31271} {RNA815_14002}
37. MligTC455_46446 44 0.92 Mlig455_064208

Neo: -

Age: -

1.728 - - 0.766 0.962 - - Mlig455_064208 {REF} {Length: 608} {RNA1509_14730} {RNA1310_29088} {RNA815_18139}
38. MligTC455_45450 66 1.38 Mlig455_061622

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.869

ZIC4 1.727 - - - 0.961 0.766 - Mlig455_061622 {REF} {Length: 1709} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=49.3]; Zinc-finger double domain [PF13465.8, score=44.8]; Zic proteins zinc finger domain [PF18366.3, score=30.5]} {Human: ENSG00000174963, ZIC4, Zic family member 4, [Score=201, Expect=5e-62]; ENSG00000156925, ZIC3, Zic family member 3, [Score=197, Expect=3e-59]; ENSG00000043355, ZIC2, Zic family member 2, [Score=197, Expect=2e-58]; ENSG00000152977, ZIC1, Zic family member 1, [Score=196, Expect=8e-59]; ENSG00000139800, ZIC5, Zic family member 5, [Score=194, Expect=1e-56]} {Mouse: ENSMUSG00000041703, Zic5, zinc finger protein of the cerebellum 5, [Score=199, Expect=9e-59]; ENSMUSG00000036972, Zic4, zinc finger protein of the cerebellum 4, [Score=197, Expect=9e-61]; ENSMUSG00000067860, Zic3, zinc finger protein of the cerebellum 3, [Score=197, Expect=2e-59]; ENSMUSG00000032368, Zic1, zinc finger protein of the cerebellum 1, [Score=196, Expect=5e-59]; ENSMUSG00000061524, Zic2, zinc finger protein of the cerebellum 2, [Score=196, Expect=1e-58]} {Dmel: FBgn0003002, opa, odd paired, [Score=194, Expect=5e-57]} {Celegans: WBGene00004335, ref-2, REgulator of Fusion, [Score=171, Expect=3e-51]} {Smed: dd_Smed_v6_15531_0_1, dd_Smed_v6_15531_0_1, [Score=214, Expect=4e-66]} {RNA1310_23362} {RNA815_19034}
39. MligTC455_41728 30 0.62 Mlig455_027804

Neo: -

Age: logFC(26M/2M)=-0.380

KATNAL2 1.722 - - 0.977 - 0.745 - Mlig455_027804 {REF} {Length: 2299} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=126.6]; AAA+ lid domain [PF17862.3, score=47.1]; LisH [PF08513.13, score=26.4]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=22.3]; AAA ATPase domain [PF13191.8, score=19.5]; TIP49 P-loop domain [PF06068.15, score=19.1]; AAA domain (dynein-related subfamily) [PF07728.16, score=18.8]; Magnesium chelatase, subunit ChlI [PF01078.23, score=18.1]} {Human: ENSG00000167216, KATNAL2, katanin catalytic subunit A1 like 2, [RH, Score=609, Expect=0.0]} {Mouse: ENSMUSG00000025420, Katnal2, katanin p60 subunit A-like 2, [RH, Score=609, Expect=0.0]} {Dmel: FBgn0040208, Kat60, Katanin 60, [Score=279, Expect=4e-86]} {Celegans: WBGene00003183, mei-1, Meiotic spindle formation protein mei-1, [Score=260, Expect=3e-80]} {Smed: dd_Smed_v6_14853_0_1, dd_Smed_v6_14853_0_1, [RH, Score=646, Expect=0.0]} {RNA1509_14139, RNA1509_56577} {RNA1310_9263.1, RNA1509_56577} {RNA1509_56577, RNA815_5637}
40. MligTC455_16293 241 5.01 Mlig455_029235

Neo: Irradiation

Age: Up-Down-Down

1.719 - - - 0.959 0.760 - Mlig455_029235 {REF} {Length: 1804} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=61.3]} {Smed: dd_Smed_v6_14355_0_1, dd_Smed_v6_14355_0_1, [Score=81.3, Expect=8e-17]} {RNA1509_14151} {RNA1310_17181} {RNA815_7262}
41. MligTC455_50740 262 5.46 Mlig455_028088

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.630/0.00016

SFRP5 1.717 - - - 0.966 0.751 - Mlig455_028088 {REF} {Length: 2548} {Pfam: Fz domain [PF01392.24, score=93.7]} {Human: ENSG00000120057, SFRP5, secreted frizzled related protein 5, [RH, Score=158, Expect=5e-44]} {Mouse: ENSMUSG00000018822, Sfrp5, secreted frizzled-related sequence protein 5, [RH, Score=156, Expect=2e-43]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=100, Expect=4e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=2e-46]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [RH, Score=164, Expect=2e-46]} {RNA1509_19129} {RNA1310_15120} {RNA815_30861}
42. MligTC455_18922 6 0.13 Mlig455_031980

Neo: -

Age: -

SCNN1B 1.714 - - - 0.959 0.755 - Mlig455_031980 {REF} {Length: 2309} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=189.9]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=71.6, Expect=2e-12]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [Score=59.7, Expect=7e-09]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=81.3, Expect=6e-16]} {Smed: dd_Smed_v6_31771_0_1, dd_Smed_v6_31771_0_1, [RH, Score=107, Expect=1e-24]} {RNA1310_77723} {RNA815_50892}
43. MligTC455_36014 1671 34.81 Mlig455_004210

Neo: -

Age: Up-Up-Down

Region-enriched R2: 2.167/0.00118

PLA2G3 1.711 - - - 0.955 0.756 - Mlig455_004210 {REF} {Length: 1631} {Pfam: Phospholipase A2 [PF05826.14, score=106.6]} {Human: ENSG00000100078, PLA2G3, phospholipase A2 group III, [RH, Score=97.4, Expect=6e-23]} {Mouse: ENSMUSG00000034579, Pla2g3, phospholipase A2, group III, [RH, Score=99.4, Expect=5e-24]} {Dmel: FBgn0030013, GIIIspla2, Phospholipase A2 group III, [RH, Score=97.8, Expect=5e-25]} {Smed: dd_Smed_v6_3851_0_2, dd_Smed_v6_3851_0_2, [RH, Score=103, Expect=4e-27]} {RNA1509_17589, RNA1509_26075, RNA1509_28230, RNA1509_8881} {RNA1310_22647, RNA1509_17589, RNA1509_26075, RNA1509_28230, RNA1509_8881} {RNA1509_17589, RNA1509_26075, RNA1509_28230, RNA1509_8881, RNA815_9445}
44. MligTC455_06333 34 0.7 Mlig455_017581

Neo: -

Age: -

1.71 - - 0.974 - 0.736 - Mlig455_017581 {REF} {Length: 423} {NoTransDecoderORF}
45. MligTC455_19430 476 9.92 Mlig455_059737

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.749

Region-enriched R2: 1.435/0.03961

WDR49 1.709 - - 0.749 0.960 - - Mlig455_059737 {REF} {Length: 4068} {Pfam: WD domain, G-beta repeat [PF00400.34, score=25.0]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=140, Expect=3e-35]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=130, Expect=1e-31]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=132, Expect=1e-32]} {RNA1509_29401, RNA1509_3708} {RNA1310_2384.2, RNA1509_29401} {RNA1509_29401, RNA815_724.1}
46. MligTC455_25080 26 0.53 Mlig455_003599

Neo: -

Age: -

1.706 - - - 0.950 0.756 - Mlig455_003599 {REF} {Length: 5206} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=49.2]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [Score=50.8, Expect=1e-07]} {RNA1509_27878} {RNA1310_28023} {RNA815_19588}
47. MligTC455_43961 30 0.62 Mlig455_027626

Neo: -

Age: -

1.704 - - - 0.965 0.739 - Mlig455_027626 {REF} {Length: 602} {Pfam: PAN domain [PF00024.28, score=26.5]; PAN domain [PF14295.8, score=21.8]} {RNA1310_35396.1} {RNA815_23500}
48. MligTC455_43690 262 5.46 Mlig455_035029, Mlig455_053437

Neo: -

Age: -

Region-enriched R2: 6.108/0.00708

WSCD2 1.701 - - - 0.958 0.743 -

Mlig455_035029 {REF} {Length: 893} {Pfam: WSC domain [PF01822.21, score=50.2]; PAN domain [PF00024.28, score=29.7]} {RNA1310_42429} {RNA815_24291.1}

Mlig455_053437 {REF} {Length: 972} {Pfam: WSC domain [PF01822.21, score=52.4]; PAN domain [PF00024.28, score=29.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=44.7, Expect=1e-05]} {RNA1310_42429} {RNA815_24291.1}
49. MligTC455_08797 17 0.36 Mlig455_035299

Neo: -

Age: -

PAX8 1.698 - - - 0.959 0.739 - Mlig455_035299 {REF} {Length: 1562} {Pfam: 'Paired box' domain [PF00292.20, score=213.8]; Homeodomain-like domain [PF13565.8, score=25.1]; Homeodomain-like domain [PF13384.8, score=20.8]} {Human: ENSG00000125618, PAX8, paired box 8, [RH, Score=219, Expect=5e-66]; ENSG00000196092, PAX5, paired box 5, [RH, Score=219, Expect=2e-67]; ENSG00000075891, PAX2, paired box 2, [RH, Score=218, Expect=4e-66]} {Mouse: ENSMUSG00000014030, Pax5, paired box 5, [RH, Score=219, Expect=1e-67]; ENSMUSG00000026976, Pax8, paired box 8, [RH, Score=219, Expect=4e-66]; ENSMUSG00000004231, Pax2, paired box 2, [RH, Score=216, Expect=7e-67]} {Dmel: FBgn0005561, sv, shaven, [Score=219, Expect=1e-64]} {Celegans: WBGene00003938, pax-2, PAX (Paired box) transcription factor, [Score=201, Expect=2e-61]} {Smed: dd_Smed_v6_10219_0_1, dd_Smed_v6_10219_0_1, [Score=226, Expect=2e-72]} {RNA1509_42244} {RNA1310_108508}
50. MligTC455_33141 65 1.36 Mlig455_033449, Mlig455_040183

Neo: -

Age: Down-Up-Down

1.698 - - - 0.958 0.740 -

Mlig455_033449 {REF} {Length: 2524} {RNA1310_22116} {RNA815_34454}

Mlig455_040183 {REF} {Length: 2528} {RNA1310_22116} {RNA815_34454}
51. MligTC455_33922 235 4.89 Mlig455_032137

Neo: -

Age: logFC(26M/2M)=-0.421

SLC7A8 1.698 - - - 0.959 0.739 - Mlig455_032137 {REF} {Length: 3423} {Pfam: Amino acid permease [PF13520.8, score=218.6]; Amino acid permease [PF00324.23, score=127.0]} {Human: ENSG00000092068, SLC7A8, solute carrier family 7 member 8, [Score=385, Expect=4e-127]; ENSG00000151012, SLC7A11, solute carrier family 7 member 11, [Score=384, Expect=2e-127]; ENSG00000103257, SLC7A5, solute carrier family 7 member 5, [Score=383, Expect=8e-127]; ENSG00000103064, SLC7A6, solute carrier family 7 member 6, [Score=371, Expect=7e-122]} {Mouse: ENSMUSG00000027737, Slc7a11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, [Score=416, Expect=1e-139]} {Dmel: FBgn0039487, gb, genderblind, [RH, Score=408, Expect=2e-136]} {Celegans: WBGene00000002, aat-1, Amino Acid Transporter, [Score=365, Expect=2e-120]} {Smed: dd_Smed_v6_4211_0_1, dd_Smed_v6_4211_0_1, [Score=436, Expect=2e-147]} {RNA1509_53982} {RNA1310_8199.1} {RNA815_2788}
52. MligTC455_27650 178 3.72 Mlig455_017720

Neo: -

Age: logFC(26M/2M)=-0.928

Region-enriched R2: 3.586/0.00082

ADAM33 1.696 - - - 0.956 0.740 - Mlig455_017720 {REF} {Length: 4499} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=124.3]; Disintegrin [PF00200.25, score=66.8]; Metallo-peptidase family M12 [PF13688.8, score=62.2]; ADAM cysteine-rich [PF08516.14, score=61.3]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=33.1]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=237, Expect=1e-64]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [Score=233, Expect=2e-63]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=230, Expect=2e-62]; ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=228, Expect=4e-61]; ENSG00000069206, ADAM7, ADAM metallopeptidase domain 7, [Score=226, Expect=4e-61]; ENSG00000042980, ADAM28, ADAM metallopeptidase domain 28, [Score=226, Expect=4e-61]} {Mouse: ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [RH, Score=248, Expect=4e-69]; ENSMUSG00000050190, Gm5346, predicted gene 5346, [RH, Score=239, Expect=3e-66]} {Dmel: FBgn0265140, Meltrin, [RH, Score=288, Expect=1e-79]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=246, Expect=3e-67]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=225, Expect=3e-60]} {RNA1509_7654} {RNA1310_9319.1} {RNA815_4173.1}
53. MligTC455_07720 6 0.12 Mlig455_061015

Neo: -

Age: -

ZIC5 1.695 - - - 0.959 0.736 - Mlig455_061015 {REF} {Length: 576} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=39.1]; Zinc-finger double domain [PF13465.8, score=33.8]; C2H2-type zinc finger [PF13894.8, score=24.2]} {Human: ENSG00000139800, ZIC5, Zic family member 5, [Score=97.1, Expect=7e-25]; ENSG00000174963, ZIC4, Zic family member 4, [Score=95.5, Expect=1e-24]; ENSG00000156925, ZIC3, Zic family member 3, [Score=95.1, Expect=3e-24]; ENSG00000043355, ZIC2, Zic family member 2, [Score=94.7, Expect=5e-24]; ENSG00000152977, ZIC1, Zic family member 1, [Score=93.6, Expect=8e-24]} {Mouse: ENSMUSG00000041703, Zic5, zinc finger protein of the cerebellum 5, [Score=97.1, Expect=5e-25]; ENSMUSG00000036972, Zic4, zinc finger protein of the cerebellum 4, [Score=95.5, Expect=5e-25]; ENSMUSG00000067860, Zic3, zinc finger protein of the cerebellum 3, [Score=95.1, Expect=1e-25]; ENSMUSG00000061524, Zic2, zinc finger protein of the cerebellum 2, [Score=94.7, Expect=3e-24]; ENSMUSG00000032368, Zic1, zinc finger protein of the cerebellum 1, [Score=93.6, Expect=5e-24]} {Dmel: FBgn0003002, opa, odd paired, [Score=96.7, Expect=5e-25]} {Celegans: WBGene00004335, ref-2, REgulator of Fusion, [Score=93.2, Expect=1e-24]} {Smed: dd_Smed_v6_22585_0_1, dd_Smed_v6_22585_0_1, [Score=100, Expect=8e-27]} {RNA1310_23362} {RNA815_19034}
54. MligTC455_50229 176 3.66 Mlig455_010733

Neo: -

Age: -

TAB1 1.693 - - 0.954 - 0.739 - Mlig455_010733 {REF} {Length: 3464} {TRANSSPLICED} {Pfam: Protein phosphatase 2C [PF00481.23, score=20.5]} {Human: ENSG00000100324, TAB1, TGF-beta activated kinase 1 (MAP3K7) binding protein 1, [RH, Score=50.8, Expect=3e-06]} {Mouse: ENSMUSG00000022414, Tab1, TGF-beta activated kinase 1/MAP3K7 binding protein 1, [RH, Score=51.2, Expect=2e-06]} {RNA1509_20706} {RNA1310_18794, RNA1509_20706} {RNA1509_20706, RNA815_17460}
55. MligTC455_19921 72 1.5 Mlig455_035338

Neo: -

Age: -

1.692 - - - 0.955 0.737 - Mlig455_035338 {REF} {Length: 818} {NoTransDecoderORF} {RNA1509_32347} {RNA1310_55518} {RNA815_50422}
56. MligTC455_14110 17 0.35 Mlig455_046797

Neo: -

Age: -

1.69 - - 0.734 0.956 - - Mlig455_046797 {REF} {Length: 2748} {RNA1509_35160} {RNA1310_58833} {RNA815_9166}
57. MligTC455_49477 647 13.47 Mlig455_057155

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.602

1.69 - - - 0.955 0.735 - Mlig455_057155 {REF} {Length: 1603} {Pfam: CD36 family [PF01130.23, score=35.1]} {RNA1509_12751} {RNA1310_21707.1} {RNA815_6814}
58. MligTC455_13885 28 0.58 Mlig455_020919

Neo: -

Age: -

1.682 - - - 0.958 0.724 - Mlig455_020919 {REF} {Length: 1208} {RNA1310_25040.4} {RNA815_12562.1}
59. MligTC455_43751 317 6.61 Mlig455_018062

Neo: -

Age: -

1.672 - - - 0.719 0.953 - Mlig455_018062 {REF} {Length: 2519} {RNA1509_20267, RNA1509_24151} {RNA1310_4680, RNA1509_20267, RNA1509_24151} {RNA1509_20267, RNA1509_24151, RNA815_3273}
60. MligTC455_36730 165 3.44 Mlig455_056961

Neo: -

Age: Up-Down-Down

1.67 - - - 0.954 0.716 - Mlig455_056961 {REF} {Length: 4865} {Pfam: Lipoma HMGIC fusion partner-like protein [PF10242.11, score=57.3]} {RNA1310_49374} {RNA815_39552}
61. MligTC455_35325 26 0.54 Mlig455_008452, Mlig455_031353, Mlig455_056519

Neo: -

Age: -

HTR3A 0.99 - - 0.990 - - -

Mlig455_008452 {REF} {Length: 1552} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=81.9]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=26.8]} {Human: ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=97.4, Expect=2e-22]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=92.8, Expect=1e-20]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=92.8, Expect=6e-21]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=91.7, Expect=2e-20]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=90.9, Expect=3e-20]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=93.2, Expect=4e-21]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=98.2, Expect=6e-23]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=88.6, Expect=9e-20]} {RNA1509_7752} {RNA1310_93708} {RNA815_49010}

Mlig455_031353 {REF} {Length: 1802} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=61.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=54.4]} {Human: ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=103, Expect=5e-25]; ENSG00000149305, HTR3B, 5-hydroxytryptamine receptor 3B, [Score=101, Expect=1e-24]} {Mouse: ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=100, Expect=4e-24]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=98.2, Expect=2e-23]; ENSMUSG00000008590, Htr3b, 5-hydroxytryptamine (serotonin) receptor 3B, [Score=96.3, Expect=7e-23]} {Dmel: FBgn0032151, nAChRalpha6, nicotinic Acetylcholine Receptor alpha6, [Score=93.6, Expect=6e-22]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=100, Expect=1e-24]} {Smed: dd_Smed_v6_11955_0_1, dd_Smed_v6_11955_0_1, [Score=90.5, Expect=5e-21]} {RNA1509_7752} {RNA1310_93708} {RNA815_49010}

Mlig455_056519 {REF} {Length: 1867} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=81.9]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=26.8]} {Human: ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=97.4, Expect=2e-22]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=92.8, Expect=1e-20]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=92.8, Expect=6e-21]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=91.7, Expect=2e-20]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=90.9, Expect=3e-20]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=93.2, Expect=4e-21]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=98.2, Expect=6e-23]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=88.6, Expect=9e-20]} {RNA1509_53098} {RNA1310_93708} {RNA815_49010}
62. MligTC455_39009 42 0.88 Mlig455_022189, Mlig455_046042

Neo: -

Age: -

0.989 - - 0.989 - - -

Mlig455_022189 {REF} {Length: 198} {NoTransDecoderORF} {RNA1509_54430} {RNA1310_59969} {RNA815_41194.1}

Mlig455_046042 {REF} {Length: 660} {NoTransDecoderORF} {RNA1509_59553} {RNA1310_127391} {RNA815_64986}
63. MligTC455_35324 9 0.18 Mlig455_031365

Neo: -

Age: -

CHRNA3 0.988 - - 0.988 - - - Mlig455_031365 {REF} {Length: 1546} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=78.7]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=27.1]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=93.2, Expect=3e-21]; ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=90.9, Expect=2e-20]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=94.4, Expect=8e-22]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=91.7, Expect=7e-21]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=90.5, Expect=2e-20]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=93.6, Expect=1e-21]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=98.2, Expect=2e-23]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=88.2, Expect=6e-20]} {RNA1509_7752} {RNA1310_93708} {RNA815_49010}
64. MligTC455_31235 298 6.22 Mlig455_007957, Mlig455_018106, Mlig455_018108, Mlig455_018110, Mlig455_024170, Mlig455_026289, Mlig455_046160, Mlig455_056610, Mlig455_061406, Mlig455_065569, Mlig455_069763

Neo: -

Age: Up-Down-Up

PRR9 0.987 - - 0.987 - - -

Mlig455_007957 {REF} {Length: 1663} {RNA1509_46145} {RNA1310_47677} {RNA815_5444.1}

Mlig455_018106 {REF} {Length: 764} {NoTransDecoderORF} {RNA1509_46145} {RNA1310_51772} {RNA815_5444.1}

Mlig455_018108 {REF} {Length: 785} {NoTransDecoderORF} {RNA1509_46145} {RNA1310_51772} {RNA815_5444.1}

Mlig455_018110 {REF} {Length: 830} {NoTransDecoderORF} {RNA1509_46145} {RNA1310_51772} {RNA815_5444.1}

Mlig455_024170 {REF} {Length: 1434} {RNA1509_5808} {RNA1310_42249} {RNA815_5444.1}

Mlig455_026289 {REF} {Length: 1433} {RNA1509_5808} {RNA1310_42249} {RNA815_5444.1}

Mlig455_046160 {REF} {Length: 836} {NoTransDecoderORF} {RNA1509_46145} {RNA1310_51772} {RNA815_5444.1}

Mlig455_056610 {REF} {Length: 1652} {RNA1509_5808} {RNA1310_42249} {RNA815_5444.1}

Mlig455_061406 {REF} {Length: 1433} {RNA1509_5808} {RNA1310_42249} {RNA815_5444.1}

Mlig455_065569 {REF} {Length: 3509} {Human: ENSG00000203783, PRR9, proline rich 9, [Score=47.4, Expect=2e-06]} {Celegans: WBGene00018026, F35A5.4, [Score=60.5, Expect=3e-10]} {RNA1509_46145} {RNA1310_42249} {RNA815_5444.1}

Mlig455_069763 {REF} {Length: 469} {NoTransDecoderORF} {RNA1509_46145} {RNA1310_9148.2} {RNA815_9953}
65. MligTC455_12105 21 0.43 Mlig455_015631

Neo: -

Age: -

0.983 - - 0.983 - - - Mlig455_015631 {REF} {Length: 1685} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=64.7]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=27.3]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=22.5]} {Smed: dd_Smed_v6_13742_0_1, dd_Smed_v6_13742_0_1, [Score=82.4, Expect=2e-17]} {RNA1310_95837}
66. MligTC455_18997 30 0.62 Mlig455_032972

Neo: -

Age: logFC(26M/2M)=-0.312

KLKB1 0.983 - - 0.983 - - - Mlig455_032972 {REF} {Length: 2301} {TRANSSPLICED} {Pfam: Trypsin [PF00089.28, score=98.3]} {Human: ENSG00000164344, KLKB1, kallikrein B1, [Score=80.9, Expect=2e-15]} {Mouse: ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=73.6, Expect=3e-13]; ENSMUSG00000049291, Prss38, protease, serine 38, [Score=70.5, Expect=7e-13]} {Dmel: FBgn0033362, CG8172, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [Score=73.2, Expect=2e-13]} {Smed: dd_Smed_v6_7481_0_1, dd_Smed_v6_7481_0_1, [RH, Score=101, Expect=1e-23]} {RNA1509_10182} {RNA1310_3302.1} {RNA815_8189.1}
67. MligTC455_03892 8 0.18 Mlig455_009194

Neo: -

Age: -

0.982 - - 0.982 - - - Mlig455_009194 {REF} {Length: 2218} {TRANSSPLICED} {Dmel: FBgn0035248, CG13919, [RH, Score=45.4, Expect=1e-05]} {Smed: dd_Smed_v6_16261_0_1, dd_Smed_v6_16261_0_1, [RH, Score=255, Expect=7e-81]} {RNA1509_28905} {RNA1310_72348.1} {RNA815_44982}
68. MligTC455_06766 45 0.93 Mlig455_058800

Neo: -

Age: -

0.982 - - 0.982 - - - Mlig455_058800 {REF} {Length: 516} {NoTransDecoderORF}
69. MligTC455_32066 127 2.64 Mlig455_048493

Neo: -

Age: Up-Down-Down

SLC17A9 0.982 - - 0.982 - - - Mlig455_048493 {REF} {Length: 5594} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=149.1]} {Human: ENSG00000101194, SLC17A9, solute carrier family 17 member 9, [RH, Score=303, Expect=1e-97]} {Mouse: ENSMUSG00000023393, Slc17a9, solute carrier family 17, member 9, [RH, Score=301, Expect=4e-97]} {Dmel: FBgn0025684, MFS18, Major Facilitator Superfamily Transporter 18, [Score=300, Expect=1e-96]} {Celegans: WBGene00010758, vnut-1, Vesicular NUcleotide Transporte, [RH, Score=313, Expect=5e-102]} {Smed: dd_Smed_v6_1326_0_1, dd_Smed_v6_1326_0_1, [Score=394, Expect=3e-133]} {RNA1509_17119} {RNA1310_13718, RNA1509_17119} {RNA1509_17119, RNA815_7003}
70. MligTC455_21595 144 2.99 Mlig455_011768, Mlig455_033798, Mlig455_033808

Neo: Irradiation

Age: Up-Down-Up

0.977 - - 0.977 - - -

Mlig455_011768 {REF} {Length: 1981} {RNA1509_56841} {RNA1310_5686} {RNA815_25602}

Mlig455_033798 {REF} {Length: 920} {Smed: dd_Smed_v6_9549_0_1, dd_Smed_v6_9549_0_1, [Score=48.9, Expect=1e-06]} {RNA1509_56841} {RNA1310_51347} {RNA815_22112}

Mlig455_033808 {REF} {Length: 365} {RNA1509_56841} {RNA1310_51347} {RNA815_22112}
71. MligTC455_28055 19 0.41 Mlig455_048300, Mlig455_048327, Mlig455_048344

Neo: -

Age: -

MARK2, MARK4 0.977 - - 0.977 - - -

Mlig455_048300 {REF} {Length: 2504} {Pfam: Protein kinase domain [PF00069.27, score=157.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=86.8]; Kinase-like [PF14531.8, score=21.5]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=21.4]} {Human: ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=158, Expect=1e-39]; ENSG00000072518, MARK2, microtubule affinity regulating kinase 2, [Score=157, Expect=2e-39]; ENSG00000075413, MARK3, microtubule affinity regulating kinase 3, [Score=152, Expect=7e-38]; ENSG00000160584, SIK3, SIK family kinase 3, [Score=152, Expect=2e-37]; ENSG00000074590, NUAK1, NUAK family kinase 1, [Score=151, Expect=1e-37]} {Mouse: ENSMUSG00000024969, Mark2, MAP/microtubule affinity regulating kinase 2, [Score=158, Expect=8e-40]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=156, Expect=3e-39]; ENSMUSG00000007411, Mark3, MAP/microtubule affinity regulating kinase 3, [Score=152, Expect=8e-38]; ENSMUSG00000009772, Nuak2, NUAK family, SNF1-like kinase, 2, [Score=151, Expect=7e-38]; ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=151, Expect=4e-37]; ENSMUSG00000020032, Nuak1, NUAK family, SNF1-like kinase, 1, [Score=151, Expect=1e-37]} {Dmel: FBgn0026064, KP78a, [Score=156, Expect=2e-39]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=163, Expect=4e-41]} {Smed: dd_Smed_v6_14823_0_1, dd_Smed_v6_14823_0_1, [Score=317, Expect=1e-97]} {RNA1310_58898} {RNA815_35373}

Mlig455_048327 {REF} {Length: 2998} {Pfam: Protein kinase domain [PF00069.27, score=157.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=86.7]; Kinase-like [PF14531.8, score=21.4]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=21.3]} {Human: ENSG00000072518, MARK2, microtubule affinity regulating kinase 2, [Score=159, Expect=1e-39]; ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=159, Expect=6e-40]; ENSG00000075413, MARK3, microtubule affinity regulating kinase 3, [Score=153, Expect=5e-38]; ENSG00000160584, SIK3, SIK family kinase 3, [Score=153, Expect=2e-37]; ENSG00000074590, NUAK1, NUAK family kinase 1, [Score=152, Expect=1e-37]} {Mouse: ENSMUSG00000024969, Mark2, MAP/microtubule affinity regulating kinase 2, [Score=159, Expect=7e-40]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=157, Expect=2e-39]; ENSMUSG00000009772, Nuak2, NUAK family, SNF1-like kinase, 2, [Score=152, Expect=5e-38]; ENSMUSG00000007411, Mark3, MAP/microtubule affinity regulating kinase 3, [Score=152, Expect=5e-38]; ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=152, Expect=3e-37]} {Dmel: FBgn0026064, KP78a, [Score=157, Expect=9e-40]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=164, Expect=2e-41]} {Smed: dd_Smed_v6_14823_0_1, dd_Smed_v6_14823_0_1, [Score=318, Expect=1e-97]} {RNA1310_58898} {RNA815_35373}

Mlig455_048344 {REF} {Length: 2992} {Pfam: Protein kinase domain [PF00069.27, score=216.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=130.0]; Kinase-like [PF14531.8, score=22.0]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=21.6]} {Human: ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=213, Expect=1e-58]; ENSG00000072518, MARK2, microtubule affinity regulating kinase 2, [Score=212, Expect=6e-58]; ENSG00000075413, MARK3, microtubule affinity regulating kinase 3, [Score=207, Expect=3e-56]; ENSG00000160584, SIK3, SIK family kinase 3, [Score=206, Expect=2e-54]} {Mouse: ENSMUSG00000024969, Mark2, MAP/microtubule affinity regulating kinase 2, [Score=212, Expect=3e-58]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=212, Expect=5e-58]; ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=207, Expect=3e-55]; ENSMUSG00000007411, Mark3, MAP/microtubule affinity regulating kinase 3, [Score=206, Expect=4e-56]} {Dmel: FBgn0026064, KP78a, [Score=213, Expect=1e-58]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=217, Expect=7e-59]} {Smed: dd_Smed_v6_14823_0_1, dd_Smed_v6_14823_0_1, [RH, Score=465, Expect=5e-154]} {RNA1310_58898} {RNA815_35373}
72. MligTC455_24279 12 0.26 Mlig455_043261

Neo: -

Age: -

Region-enriched R4: 7.255/0.02204

0.976 - - 0.976 - - - Mlig455_043261 {REF} {Length: 4510} {Smed: dd_Smed_v6_4351_0_1, dd_Smed_v6_4351_0_1, [RH, Score=233, Expect=3e-72]} {RNA1509_37187} {RNA1310_9833.1} {RNA815_9014.1}
73. MligTC455_36334 30 0.62 Mlig455_041900

Neo: -

Age: Up-Up-Down

Region-enriched R2: 9.749/0.00702

URGCP 0.976 - - 0.976 - - - Mlig455_041900 {REF} {Length: 7730} {Pfam: Dynamin family [PF00350.25, score=22.8]; 50S ribosome-binding GTPase [PF01926.25, score=20.2]} {Human: ENSG00000106608, URGCP, upregulator of cell proliferation, [RH, Score=216, Expect=4e-57]} {Mouse: ENSMUSG00000078606, Gm4070, predicted gene 4070, [RH, Score=527, Expect=1e-154]; ENSMUSG00000045868, Gvin1, GTPase, very large interferon inducible 1, [RH, Score=527, Expect=1e-154]} {RNA1509_40173} {RNA1310_4704.1, RNA1509_40173} {RNA1509_40173, RNA815_32622}
74. MligTC455_06845 32 0.67 Mlig455_060389

Neo: -

Age: -

0.975 - - 0.975 - - - Mlig455_060389 {REF} {Length: 566} {NoTransDecoderORF}
75. MligTC455_37605 93 1.94 Mlig455_049970

Neo: -

Age: -

Region-enriched R2: 3.447/0.02471

SNTG1 0.975 - - - 0.975 - - Mlig455_049970 {REF} {Length: 9283} {Pfam: PDZ domain [PF00595.26, score=57.0]; Chromo (CHRromatin Organisation MOdifier) domain [PF00385.26, score=26.9]; PDZ domain [PF13180.8, score=20.3]} {Human: ENSG00000147481, SNTG1, syntrophin gamma 1, [RH, Score=132, Expect=1e-31]} {Mouse: ENSMUSG00000025909, Sntg1, syntrophin, gamma 1, [RH, Score=130, Expect=6e-31]} {Dmel: FBgn0034135, Syn2, Syntrophin-like 2, [RH, Score=179, Expect=3e-47]} {Celegans: WBGene00017866, stn-2, SynTrophiN, [RH, Score=117, Expect=5e-27]} {Smed: dd_Smed_v6_7105_0_1, dd_Smed_v6_7105_0_1, [Score=87.0, Expect=3e-17]} {RNA1509_51193} {RNA1310_6769} {RNA815_11182}
76. MligTC455_50177 26 0.55 Mlig455_050182

Neo: -

Age: -

0.973 - - 0.973 - - - Mlig455_050182 {REF} {Length: 1326} {RNA1310_32436}
77. MligTC455_18579 143 2.97 Mlig455_047208, Mlig455_048469

Neo: -

Age: -

GRIK2, GRIK3 0.972 - - - 0.972 - -

Mlig455_047208 {REF} {Length: 5413} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=92.5]; Ligand-gated ion channel [PF00060.28, score=84.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=49.2]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=194, Expect=2e-50]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=193, Expect=5e-50]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=192, Expect=2e-49]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=192, Expect=2e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=191, Expect=3e-49]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=194, Expect=1e-50]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=194, Expect=3e-50]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=191, Expect=2e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=191, Expect=2e-49]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=188, Expect=2e-48]} {Dmel: FBgn0038837, CG3822, [Score=185, Expect=9e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=200, Expect=7e-53]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=341, Expect=5e-106]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}

Mlig455_048469 {REF} {Length: 3740} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=95.9]; Ligand-gated ion channel [PF00060.28, score=82.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=51.5]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=190, Expect=6e-50]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=187, Expect=5e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=185, Expect=3e-48]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=184, Expect=1e-47]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=189, Expect=7e-50]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=187, Expect=6e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=185, Expect=2e-48]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=183, Expect=9e-48]} {Dmel: FBgn0038837, CG3822, [Score=183, Expect=4e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=183, Expect=3e-48]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=338, Expect=6e-108]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}
78. MligTC455_14029 53 1.11 Mlig455_022439

Neo: -

Age: -

0.971 - - - 0.971 - - Mlig455_022439 {REF} {Length: 2874} {RNA1509_36146} {RNA1310_30590} {RNA815_37384}
79. MligTC455_21756 20 0.42 Mlig455_057868

Neo: -

Age: -

0.971 - - - 0.971 - - Mlig455_057868 {REF} {Length: 1746} {Pfam: F5/8 type C domain [PF00754.27, score=36.3]} {RNA1310_33166} {RNA815_14716}
80. MligTC455_29085 34 0.72 Mlig455_047082

Neo: -

Age: -

RASGRF2 0.971 - - - 0.971 - - Mlig455_047082 {REF} {Length: 6322} {Pfam: RasGEF domain [PF00617.21, score=194.4]; RhoGEF domain [PF00621.22, score=120.6]; RasGEF N-terminal motif [PF00618.22, score=68.8]; PH domain [PF00169.31, score=20.4]} {Human: ENSG00000113319, RASGRF2, Ras protein specific guanine nucleotide releasing factor 2, [Score=570, Expect=0.0]; ENSG00000058335, RASGRF1, Ras protein specific guanine nucleotide releasing factor 1, [Score=566, Expect=3e-178]} {Mouse: ENSMUSG00000032356, Rasgrf1, RAS protein-specific guanine nucleotide-releasing factor 1, [Score=565, Expect=5e-178]} {Dmel: FBgn0001965, Sos, Son of sevenless, [Score=167, Expect=4e-41]} {Celegans: WBGene00004947, sos-1, Son of sevenless homolog, [Score=119, Expect=1e-26]} {Smed: dd_Smed_v6_18313_0_2, dd_Smed_v6_18313_0_2, [Score=815, Expect=0.0]} {RNA1509_15697, RNA1509_53969} {RNA1310_2543.1, RNA1509_53969} {RNA1509_53969, RNA815_8228.1}
81. MligTC455_03895 18 0.37 Mlig455_009197, Mlig455_009619

Neo: -

Age: Down-Up-Down

0.97 - - 0.970 - - -

Mlig455_009197 {REF} {Length: 1774} {Smed: dd_Smed_v6_16261_0_1, dd_Smed_v6_16261_0_1, [Score=254, Expect=7e-82]} {RNA1310_72348.1} {RNA815_44982}

Mlig455_009619 {REF} {Length: 1794} {Smed: dd_Smed_v6_16261_0_1, dd_Smed_v6_16261_0_1, [Score=254, Expect=7e-82]} {RNA1310_72348.1} {RNA815_44982}
82. MligTC455_14716 29 0.61 Mlig455_043633

Neo: -

Age: -

ANGPTL2 0.97 - - - 0.970 - - Mlig455_043633 {REF} {Length: 1106} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=157.6]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=134, Expect=2e-35]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=133, Expect=4e-35]; ENSG00000085265, FCN1, ficolin 1, [Score=132, Expect=8e-36]; ENSG00000160339, FCN2, ficolin 2, [Score=128, Expect=4e-35]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=137, Expect=1e-36]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=134, Expect=1e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=131, Expect=1e-34]} {Dmel: FBgn0034160, CG5550, [Score=119, Expect=6e-32]} {Celegans: WBGene00017013, ensh-1, [Score=57.8, Expect=2e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=114, Expect=1e-28]} {RNA1509_26827} {RNA1310_31596.2} {RNA815_17173.3}
83. MligTC455_26296 29 0.6 Mlig455_039775

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.567

0.97 - - 0.970 - - - Mlig455_039775 {REF} {Length: 11147} {RNA1509_17190} {RNA1310_9848.1} {RNA815_5685.1}
84. MligTC455_41339 61 1.27 Mlig455_021120

Neo: -

Age: -

0.97 - - - 0.970 - - Mlig455_021120 {REF} {Length: 294} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_118897} {RNA815_62550}
85. MligTC455_28739 31 0.64 Mlig455_039004

Neo: -

Age: -

TANC2 0.969 - - - 0.969 - - Mlig455_039004 {REF} {Length: 5623} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=44.5]; Mab-21 protein [PF03281.16, score=43.7]; Ankyrin repeats (3 copies) [PF12796.9, score=42.7]; Ankyrin repeats (many copies) [PF13857.8, score=40.3]; Ankyrin repeat [PF13606.8, score=35.3]; Ankyrin repeat [PF00023.32, score=31.4]} {Human: ENSG00000170921, TANC2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=69.3, Expect=2e-11]; ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=66.2, Expect=3e-10]} {Mouse: ENSMUSG00000053580, Tanc2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=69.3, Expect=2e-11]; ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=67.0, Expect=1e-10]} {Dmel: FBgn0041096, rols, rolling pebbles, [Score=62.8, Expect=1e-09]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=57.4, Expect=5e-08]} {Smed: dd_Smed_v6_12936_0_1, dd_Smed_v6_12936_0_1, [Score=65.1, Expect=2e-10]} {RNA1509_27730} {RNA1310_1764.1} {RNA815_5358.1}
86. MligTC455_06441 61 1.28 Mlig455_001110

Neo: -

Age: -

0.968 - - - 0.968 - - Mlig455_001110 {REF} {Length: 808} {RNA1509_59645} {RNA1310_6160.2} {RNA815_48228}
87. MligTC455_13682 42 0.87 Mlig455_030673

Neo: -

Age: -

0.968 - - - 0.968 - - Mlig455_030673 {REF} {Length: 2472} {Pfam: gag-polyprotein putative aspartyl protease [PF13975.8, score=21.9]} {RNA1509_51609} {RNA1310_3461} {RNA815_16498}
88. MligTC455_47691 103 2.14 Mlig455_046561

Neo: -

Age: -

UBTD2 0.968 - - 0.968 - - - Mlig455_046561 {REF} {Length: 3785} {Pfam: Ubiquitin-binding domain [PF16455.7, score=121.7]; Ubiquitin family [PF00240.25, score=33.5]} {Human: ENSG00000168246, UBTD2, ubiquitin domain containing 2, [RH, Score=218, Expect=9e-71]} {Mouse: ENSMUSG00000044949, Ubtd2, ubiquitin domain containing 2, [RH, Score=219, Expect=2e-71]} {Dmel: FBgn0264712, CG1172, [RH, Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_3009_0_1, dd_Smed_v6_3009_0_1, [RH, Score=198, Expect=4e-63]} {RNA1509_42408} {RNA1310_33971} {RNA815_34971}
89. MligTC455_53418 24 0.51 Mlig455_070635

Neo: -

Age: logFC(26M/2M)=-0.617

ZBTB8A 0.968 - - 0.968 - - - Mlig455_070635 {REF} {Length: 2314} {Pfam: NPH3 family [PF03000.16, score=43.7]; BTB/POZ domain [PF00651.33, score=42.1]} {Human: ENSG00000160062, ZBTB8A, zinc finger and BTB domain containing 8A, [Score=51.2, Expect=2e-06]; ENSG00000148411, NACC2, NACC family member 2, [Score=49.7, Expect=1e-05]} {Mouse: ENSMUSG00000026932, Nacc2, nucleus accumbens associated 2, BEN and BTB (POZ) domain containing, [Score=50.4, Expect=4e-06]; ENSMUSG00000028807, Zbtb8a, zinc finger and BTB domain containing 8a, [Score=50.1, Expect=4e-06]} {Smed: dd_Smed_v6_8081_0_1, dd_Smed_v6_8081_0_1, [Score=185, Expect=9e-52]} {RNA1509_2983} {RNA1310_41353} {RNA815_5532.1}
90. MligTC455_06774 13 0.28 Mlig455_032313

Neo: -

Age: -

0.967 - - - 0.967 - - Mlig455_032313 {REF} {Length: 688} {RNA1509_2515} {RNA1310_5479.2} {RNA815_3258.1}
91. MligTC455_32591 24 0.49 Mlig455_055614

Neo: -

Age: -

0.967 - - 0.967 - - - Mlig455_055614 {REF} {Length: 5666} {RNA1509_50311} {RNA1310_1521.1} {RNA815_920.1}
92. MligTC455_50148 595 12.39 Mlig455_006502, Mlig455_006621

Neo: -

Age: -

Region-enriched R4: 1.783/0.00382

ZBBX 0.967 - - - 0.967 - -

Mlig455_006502 {REF} {Length: 3171} {TRANSSPLICED} {Pfam: Cytoplasmic polyadenylation element-binding protein ZZ domain [PF16366.7, score=18.8]} {Human: ENSG00000169064, ZBBX, zinc finger B-box domain containing, [RH, Score=78.6, Expect=3e-14]} {Mouse: ENSMUSG00000034151, Zbbx, zinc finger, B-box domain containing, [RH, Score=89.4, Expect=6e-18]} {Smed: dd_Smed_v6_11048_0_1, dd_Smed_v6_11048_0_1, [RH, Score=139, Expect=3e-34]} {RNA1509_10989, RNA1509_54948} {RNA1310_3743, RNA1509_10989, RNA1509_54948} {RNA1509_10989, RNA1509_54948, RNA815_5872}

Mlig455_006621 {REF} {Length: 3128} {TRANSSPLICED} {Human: ENSG00000169064, ZBBX, zinc finger B-box domain containing, [RH, Score=80.1, Expect=9e-15]} {Mouse: ENSMUSG00000034151, Zbbx, zinc finger, B-box domain containing, [RH, Score=89.0, Expect=9e-18]} {Smed: dd_Smed_v6_11048_0_1, dd_Smed_v6_11048_0_1, [RH, Score=139, Expect=3e-34]} {RNA1509_10989} {RNA1310_3743} {RNA815_5872}
93. MligTC455_08159 10 0.2 Mlig455_047455

Neo: -

Age: -

MSC 0.965 - - - 0.965 - - Mlig455_047455 {REF} {Length: 932} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=51.4]} {Human: ENSG00000178860, MSC, musculin, [RH, Score=84.7, Expect=2e-19]; ENSG00000118526, TCF21, transcription factor 21, [RH, Score=84.7, Expect=9e-20]} {Mouse: ENSMUSG00000045680, Tcf21, transcription factor 21, [RH, Score=84.7, Expect=6e-20]; ENSMUSG00000025930, Msc, musculin, [RH, Score=84.3, Expect=1e-19]} {Dmel: FBgn0022740, HLH54F, [RH, Score=79.7, Expect=1e-17]} {Celegans: WBGene00003018, lin-32, [Score=62.4, Expect=3e-12]} {Smed: dd_Smed_v6_16070_0_1, dd_Smed_v6_16070_0_1, [RH, Score=73.9, Expect=4e-16]}
94. MligTC455_17241 51 1.06 Mlig455_031641

Neo: -

Age: -

0.965 - - 0.965 - - - Mlig455_031641 {REF} {Length: 1430} {NoTransDecoderORF} {RNA1509_31207} {RNA815_58763}
95. MligTC455_37348 120 2.51 Mlig455_035496

Neo: -

Age: logFC(26M/2M)=-0.336

0.965 - - - 0.965 - - Mlig455_035496 {REF} {Length: 1891} {RNA1509_47045} {RNA1310_21549} {RNA815_8187}
96. MligTC455_17890 43 0.89 Mlig455_036597, Mlig455_057755

Neo: -

Age: -

0.964 - - - 0.964 - -

Mlig455_036597 {REF} {Length: 1176} {RNA1310_32799.1} {RNA815_33356}

Mlig455_057755 {REF} {Length: 1238} {RNA1310_32799.1} {RNA815_33356}
97. MligTC455_29698 153 3.19 Mlig455_038104

Neo: -

Age: logFC(26M/2M)=-0.330

ANKRD17 0.964 - - - 0.964 - - Mlig455_038104 {REF} {Length: 7732} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=444.0]; Ankyrin repeats (many copies) [PF13637.8, score=254.7]; Ankyrin repeats (many copies) [PF13857.8, score=146.5]; Ankyrin repeat [PF13606.8, score=141.2]; Transcription factor BRX N-terminal domain [PF13713.8, score=129.7]; Ankyrin repeat [PF00023.32, score=103.7]; Domain of unknown function (DUF4476) [PF14771.8, score=54.5]; Mab-21 protein [PF03281.16, score=36.7]; HEAT repeats [PF13646.8, score=20.0]; Protein of unknown function (DUF3307) [PF11750.10, score=18.9]} {Human: ENSG00000132466, ANKRD17, ankyrin repeat domain 17, [Score=167, Expect=1e-40]} {Mouse: ENSMUSG00000055204, Ankrd17, ankyrin repeat domain 17, [Score=166, Expect=2e-40]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=114, Expect=7e-25]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=120, Expect=8e-27]} {Smed: dd_Smed_v6_5303_0_2, dd_Smed_v6_5303_0_2, [Score=160, Expect=2e-39]} {RNA1509_27730, RNA1509_55013} {RNA1310_21755.1, RNA1509_55013} {RNA1509_55013, RNA815_2426.1}
98. MligTC455_29834 17 0.36 Mlig455_063213

Neo: -

Age: -

0.964 - - 0.964 - - - Mlig455_063213 {REF} {Length: 1127} {TRANSSPLICED} {RNA1509_20954} {RNA1310_33964.1} {RNA815_10226}
99. MligTC455_41338 68 1.41 Mlig455_007838

Neo: -

Age: Up-Up-Down

0.964 - - - 0.964 - - Mlig455_007838 {REF} {Length: 4757} {RNA1310_34392} {RNA815_25763}
100. MligTC455_52494 100 2.08 Mlig455_013751

Neo: -

Age: -

Region-enriched R6: 6.660/0.00069

BEST4 0.964 - - - 0.964 - - Mlig455_013751 {REF} {Length: 1713} {Pfam: Bestrophin, RFP-TM, chloride channel [PF01062.23, score=176.9]} {Human: ENSG00000142959, BEST4, bestrophin 4, [Score=187, Expect=2e-53]} {Mouse: ENSMUSG00000037418, Best1, bestrophin 1, [Score=181, Expect=2e-50]} {Dmel: FBgn0040238, Best1, Bestrophin 1, [Score=198, Expect=6e-56]} {Celegans: WBGene00022797, best-24, Bestrophin homolog 24, [Score=168, Expect=1e-45]} {Smed: dd_Smed_v6_22175_0_4, dd_Smed_v6_22175_0_4, [Score=295, Expect=7e-95]} {RNA1310_16906} {RNA815_14720}

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