Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_30731 | 798 | 16.63 | Mlig455_016279 | Neo: - Age: - Region-enriched R7: 3.822/0.00000 Regeneration-upregulated R5: 2.132 Regeneration-enriched R5: 2.132 |
FZD10 | Mlig455_016279 {REF} {Length: 2773} {TRANSSPLICED} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=283.8]; Fz domain [PF01392.24, score=62.9]} {Human: ENSG00000111432, FZD10, frizzled class receptor 10, [Score=270, Expect=4e-81]; ENSG00000174804, FZD4, frizzled class receptor 4, [Score=258, Expect=4e-77]} {Mouse: ENSMUSG00000081683, Fzd10, frizzled class receptor 10, [Score=261, Expect=5e-78]; ENSMUSG00000049551, Fzd9, frizzled class receptor 9, [Score=257, Expect=2e-76]; ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [Score=256, Expect=7e-77]} {Dmel: FBgn0001085, fz, frizzled, [Score=193, Expect=5e-53]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=211, Expect=7e-60]} {Smed: dd_Smed_v6_11650_0_1, dd_Smed_v6_11650_0_1, [RH, Score=294, Expect=3e-90]} {RNA1509_37398} {RNA1310_7049.2, RNA1509_37398} {RNA1509_37398, RNA815_9590.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -6.74 | 4.12 | 0.05083 | 0.53010 | |
RegionR2 | -1.528 | 4.12 | 0.99673 | 1.00000 | |
RegionR3 | -0.239 | 4.12 | 0.91325 | 1.00000 | |
RegionR4 | -0.876 | 4.12 | 0.98161 | 1.00000 | |
RegionR5 | -0.247 | 4.12 | 0.91450 | 1.00000 | |
RegionR6 | 2.186 | 4.12 | 0.00001 | 0.00155 | |
RegionR7 | 3.822 | 4.12 | 0.00000 | 0.00000 | |
RegionR8 | 3.623 | 4.12 | 0.00000 | 0.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 7.014 | 4.12 | 0.07587 | 0.76505 | |
RegenerationR2 | 0.985 | 4.12 | 0.11082 | 0.52044 | |
RegenerationR3 | 1.009 | 4.12 | 0.04322 | 0.36350 | |
RegenerationR4 | 1.476 | 4.12 | 0.00096 | 0.03403 | |
RegenerationR5 | 2.132 | 4.12 | 0.00000 | 0.00009 | Specific for R5: 2.132 |
RegenerationR6 | 1.329 | 4.12 | 0.00017 | 0.01202 | |
RegenerationBL | 0.52 | 4.12 | 0.14331 | 0.45132 | |
RegenerationTP | 0.023 | 4.12 | 0.95406 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_30731 | 798 | 16.63 | Mlig455_016279 | Neo: - Age: - Region-enriched R7: 3.822/0.00000 Regeneration-upregulated R5: 2.132 Regeneration-enriched R5: 2.132 |
FZD10 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_016279 {REF} {Length: 2773} {TRANSSPLICED} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=283.8]; Fz domain [PF01392.24, score=62.9]} {Human: ENSG00000111432, FZD10, frizzled class receptor 10, [Score=270, Expect=4e-81]; ENSG00000174804, FZD4, frizzled class receptor 4, [Score=258, Expect=4e-77]} {Mouse: ENSMUSG00000081683, Fzd10, frizzled class receptor 10, [Score=261, Expect=5e-78]; ENSMUSG00000049551, Fzd9, frizzled class receptor 9, [Score=257, Expect=2e-76]; ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [Score=256, Expect=7e-77]} {Dmel: FBgn0001085, fz, frizzled, [Score=193, Expect=5e-53]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=211, Expect=7e-60]} {Smed: dd_Smed_v6_11650_0_1, dd_Smed_v6_11650_0_1, [RH, Score=294, Expect=3e-90]} {RNA1509_37398} {RNA1310_7049.2, RNA1509_37398} {RNA1509_37398, RNA815_9590.1} |
2. | MligTC455_51406 | 1354 | 28.2 | Mlig455_069039 | Neo: - Age: - Region-enriched R8: 3.851/0.00000 |
CDX2 | 4.348 | - | 0.920 | 0.953 | 0.837 | 0.914 | 0.724 | Mlig455_069039 {REF} {Length: 2696} {Pfam: Homeodomain [PF00046.31, score=64.2]; Homeobox KN domain [PF05920.13, score=19.1]} {Human: ENSG00000165556, CDX2, caudal type homeobox 2, [RH, Score=106, Expect=6e-26]; ENSG00000113722, CDX1, caudal type homeobox 1, [RH, Score=103, Expect=5e-25]; ENSG00000131264, CDX4, caudal type homeobox 4, [RH, Score=101, Expect=2e-24]} {Mouse: ENSMUSG00000029646, Cdx2, caudal type homeobox 2, [RH, Score=109, Expect=3e-27]} {Dmel: FBgn0000251, cad, caudal, [RH, Score=102, Expect=4e-24]} {Celegans: WBGene00003912, pal-1, Homeobox protein pal-1, [RH, Score=95.1, Expect=2e-22]} {Smed: dd_Smed_v6_20296_0_1, dd_Smed_v6_20296_0_1, [Score=71.2, Expect=2e-14]} {RNA1509_24255} {RNA1310_24299.1} {RNA815_9641} |
3. | MligTC455_13295 | 567 | 11.82 | Mlig455_033272 | Neo: - Age: Down-Down-Up, logFC(26M/2M)=-0.649 Region-specific R7: 5.845 Region-enriched R8: 5.734/0.00000 Regeneration-upregulated R3: 3.842 Regeneration-enriched R3: 3.842 |
3.464 | 0.815 | 0.985 | 0.922 | 0.742 | - | - | Mlig455_033272 {REF} {Length: 1531} {RNA1509_39118} {RNA1310_21237, RNA1509_39118} {RNA1509_39118, RNA815_19007} | |
4. | MligTC455_13294 | 328 | 6.83 | Mlig455_003811 | Neo: - Age: Down-Down-Up, logFC(26M/2M)=-0.593 Region-enriched R8: 5.701/0.00000 |
3.309 | 0.788 | 0.962 | 0.767 | 0.792 | - | - | Mlig455_003811 {REF} {Length: 1567} {RNA1509_39118} {RNA1310_21237} {RNA815_19007} | |
5. | MligTC455_42723 | 666 | 13.88 | Mlig455_069654 | Neo: Irradiation Age: - Region-enriched R7: 2.955/0.00360 Regeneration-upregulated BL: 3.069 Regeneration-enriched BL: 3.069 |
2.651 | 0.842 | - | 0.951 | - | 0.858 | - | Mlig455_069654 {REF} {Length: 1471} {RNA1310_30663.1} {RNA815_50207} | |
6. | MligTC455_23734 | 1421 | 29.6 | Mlig455_015558 | Neo: - Age: logFC(26M/2M)=-1.225 |
YWHAG | 2.611 | - | - | 0.739 | 0.919 | - | 0.953 | Mlig455_015558 {REF} {Length: 1646} {TRANSSPLICED} {Pfam: 14-3-3 protein [PF00244.22, score=216.2]} {Human: ENSG00000170027, YWHAG, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma, [Score=197, Expect=1e-63]; ENSG00000274474, YWHAE, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon, [Score=196, Expect=4e-63]; ENSG00000108953, YWHAE, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon, [Score=196, Expect=4e-63]; ENSG00000164924, YWHAZ, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta, [Score=194, Expect=1e-63]; ENSG00000128245, YWHAH, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta, [Score=192, Expect=1e-61]; ENSG00000134308, YWHAQ, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta, [Score=192, Expect=8e-62]; ENSG00000166913, YWHAB, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta, [Score=192, Expect=1e-61]} {Mouse: ENSMUSG00000051391, Ywhag, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide, [Score=197, Expect=9e-64]; ENSMUSG00000020849, Ywhae, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide, [Score=195, Expect=7e-63]; ENSMUSG00000018326, Ywhab, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide, [Score=194, Expect=9e-63]; ENSMUSG00000022285, Ywhaz, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, [Score=193, Expect=3e-62]; ENSMUSG00000076432, Ywhaq, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta, [Score=191, Expect=2e-61]; ENSMUSG00000018965, Ywhah, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide, [Score=191, Expect=2e-61]} {Dmel: FBgn0004907, 14-3-3zeta, [Score=204, Expect=1e-66]} {Celegans: WBGene00001502, ftt-2, 14-3-3-like protein 2, [Score=202, Expect=8e-66]} {Smed: dd_Smed_v6_5419_0_1, dd_Smed_v6_5419_0_1, [Score=207, Expect=1e-67]} {RNA1509_8237} {RNA1310_9959} {RNA815_12064} |
7. | MligTC455_24496 | 662 | 13.79 | Mlig455_038081 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-1.244 Region-enriched R8: 6.186/0.00000 |
2.603 | 0.817 | 0.958 | 0.828 | - | - | - | Mlig455_038081 {REF} {Length: 1293} {RNA1509_9617} {RNA1310_33130} {RNA815_14842} | |
8. | MligTC455_27347 | 208457 | 4342.84 | Mlig455_029731, Mlig455_029733, Mlig455_029734, Mlig455_034875, Mlig455_034878, Mlig455_034891 | Neo: - Age: Down-Down-Down, logFC(26M/2M)=-2.046 Region-enriched R8: 1.565/0.01423 |
2.601 | 0.865 | 0.957 | 0.779 | - | - | - | Mlig455_029731 {REF} {Length: 691} {RNA1509_25} {RNA1310_29531} {RNA815_10152.2} Mlig455_029733 {REF} {Length: 585} {RNA1509_25} {RNA1310_29531} {RNA815_10152.2} Mlig455_029734 {REF} {Length: 691} {RNA1509_25} {RNA1310_29531} {RNA815_10152.1} Mlig455_034875 {REF} {Length: 807} {RNA1509_16846, RNA1509_30861} {RNA1310_51783, RNA1509_16846} {RNA1509_16846, RNA815_10152.1} Mlig455_034878 {REF} {Length: 667} {RNA1509_30861} {RNA1310_51783} {RNA815_10152.1} Mlig455_034891 {REF} {Length: 694} {RNA1509_1031, RNA1509_30861, RNA1509_3348, RNA1509_7571} {RNA1310_51783, RNA1509_1031, RNA1509_3348, RNA1509_7571} {RNA1509_1031, RNA1509_3348, RNA1509_7571, RNA815_10152.1} |
|
9. | MligTC455_24233 | 1389 | 28.94 | Mlig455_015111, Mlig455_015229 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=1.177 Region-enriched R7: 3.394/0.00000 |
SEC24A | 2.574 | - | 0.737 | 0.962 | - | - | 0.875 | Mlig455_015111 {REF} {Length: 806} {RNA1509_54513} {RNA1310_72930, RNA1509_54513} {RNA1509_54513, RNA815_39711} Mlig455_015229 {REF} {Length: 809} {Pfam: Sec23/Sec24 trunk domain [PF04811.17, score=107.9]; Sec23/Sec24 beta-sandwich domain [PF08033.14, score=67.4]; Sec23/Sec24 helical domain [PF04815.17, score=62.6]; Sec23/Sec24 zinc finger [PF04810.17, score=52.5]; Gelsolin repeat [PF00626.24, score=31.0]} {Human: ENSG00000113615, SEC24A, SEC24 homolog A, COPII coat complex component, [Score=662, Expect=0.0]; ENSG00000138802, SEC24B, SEC24 homolog B, COPII coat complex component, [Score=646, Expect=0.0]} {Mouse: ENSMUSG00000036391, Sec24a, Sec24 related gene family, member A (S. cerevisiae), [Score=667, Expect=0.0]} {Dmel: FBgn0033460, Sec24AB, Secretory 24AB, [Score=600, Expect=0.0]} {Celegans: WBGene00004756, sec-24.2, Yeast SEC homolog, [Score=511, Expect=1e-165]} {Smed: dd_Smed_v6_3760_0_1, dd_Smed_v6_3760_0_1, [Score=514, Expect=2e-167]} {RNA1509_54513} {RNA1310_72930} {RNA815_39711} |
10. | MligTC455_24234 | 695 | 14.48 | Mlig455_027186 | Neo: - Age: - Region-enriched R7: 3.405/0.00000 |
SEC24A | 2.574 | - | 0.737 | 0.962 | - | - | 0.875 | Mlig455_027186 {REF} {Length: 3445} {TRANSSPLICED} {Pfam: Sec23/Sec24 trunk domain [PF04811.17, score=107.9]; Sec23/Sec24 beta-sandwich domain [PF08033.14, score=67.4]; Sec23/Sec24 helical domain [PF04815.17, score=62.6]; Sec23/Sec24 zinc finger [PF04810.17, score=52.5]; Gelsolin repeat [PF00626.24, score=31.0]} {Human: ENSG00000113615, SEC24A, SEC24 homolog A, COPII coat complex component, [Score=662, Expect=0.0]; ENSG00000138802, SEC24B, SEC24 homolog B, COPII coat complex component, [Score=646, Expect=0.0]} {Mouse: ENSMUSG00000036391, Sec24a, Sec24 related gene family, member A (S. cerevisiae), [Score=667, Expect=0.0]} {Dmel: FBgn0033460, Sec24AB, Secretory 24AB, [Score=600, Expect=0.0]} {Celegans: WBGene00004756, sec-24.2, Yeast SEC homolog, [Score=511, Expect=1e-165]} {Smed: dd_Smed_v6_3760_0_1, dd_Smed_v6_3760_0_1, [Score=514, Expect=2e-167]} {RNA1509_10942} {RNA1310_4964} {RNA815_5061} |
11. | MligTC455_44422 | 527 | 10.98 | Mlig455_022718 | Neo: - Age: - Region-enriched R6: 1.348/0.01141 |
CREBRF | 1.878 | - | - | - | 0.922 | - | 0.956 | Mlig455_022718 {REF} {Length: 2918} {TRANSSPLICED} {Pfam: bZIP transcription factor [PF00170.23, score=24.9]} {Human: ENSG00000164463, CREBRF, CREB3 regulatory factor, [RH, Score=74.7, Expect=9e-14]} {Mouse: ENSMUSG00000048249, Crebrf, CREB3 regulatory factor, [RH, Score=74.7, Expect=8e-14]} {Dmel: FBgn0039209, REPTOR, Repressed by TOR, [RH, Score=100, Expect=4e-22]} {Smed: dd_Smed_v6_6373_0_1, dd_Smed_v6_6373_0_1, [RH, Score=60.1, Expect=6e-10]} {RNA1509_17556} {RNA1310_18927.1, RNA1509_17556} {RNA1509_17556, RNA815_13663.1} |
12. | MligTC455_20404 | 2355 | 49.05 | Mlig455_053980 | Neo: - Age: - Region-enriched R7: 4.495/0.00000 Regeneration-downregulated BL: -4.662 Regeneration-depleted BL: -4.662 |
1.867 | - | 0.959 | 0.908 | - | - | - | Mlig455_053980 {REF} {Length: 505} {NoTransDecoderORF} {RNA1509_5548} {RNA1310_94516} {RNA815_53532} | |
13. | MligTC455_53279 | 2935 | 61.14 | Mlig455_017965 | Neo: - Age: Down-Up-Down Region-specific R8: 3.606 Region-enriched R8: 3.165/0.00000 Regeneration-downregulated BL: -2.902 Regeneration-depleted BL: -2.902 |
1.809 | - | 0.951 | 0.858 | - | - | - | Mlig455_017965 {REF} {Length: 1023} {RNA1509_20769, RNA1509_34269} {RNA1310_44808, RNA1509_20769, RNA1509_34269} {RNA1509_20769, RNA1509_34269, RNA815_8213} | |
14. | MligTC455_20401 | 11443 | 238.4 | Mlig455_013098, Mlig455_013191 | Neo: - Age: Up-Down-Up Region-enriched R7: 5.239/0.00000 Regeneration-downregulated BL: -6.183 Regeneration-depleted BL: -6.183 |
1.765 | - | 0.982 | 0.783 | - | - | - | Mlig455_013098 {REF} {Length: 379} {RNA1509_2705} {RNA1310_107754} {RNA815_47935} Mlig455_013191 {REF} {Length: 379} {RNA1509_2705} {RNA1310_107754} {RNA815_47935} |
|
15. | MligTC455_20580 | 536 | 11.17 | Mlig455_001212 | Neo: Int S/G2/M Age: - |
BRDT | 1.749 | - | - | - | 0.955 | - | 0.794 | Mlig455_001212 {REF} {Length: 4402} {TRANSSPLICED} {Pfam: Bromodomain [PF00439.27, score=113.0]; Bromodomain extra-terminal - transcription regulation [PF17035.7, score=91.3]} {Human: ENSG00000137948, BRDT, bromodomain testis associated, [RH, Score=229, Expect=3e-62]} {Mouse: ENSMUSG00000024002, Brd4, bromodomain containing 4, [RH, Score=128, Expect=2e-29]; ENSMUSG00000024335, Brd2, bromodomain containing 2, [RH, Score=126, Expect=3e-29]; ENSMUSG00000026918, Brd3, bromodomain containing 3, [RH, Score=122, Expect=3e-28]} {Dmel: FBgn0004656, fs(1)h, female sterile (1) homeotic, [RH, Score=126, Expect=4e-29]} {Celegans: WBGene00022473, bet-1, Bromodomain-containing protein bet-1, [RH, Score=194, Expect=3e-51]} {Smed: dd_Smed_v6_5367_0_1, dd_Smed_v6_5367_0_1, [Score=277, Expect=2e-81]} {RNA1509_19830, RNA1509_4992} {RNA1310_1828.1, RNA1509_19830, RNA1509_4992} {RNA1509_19830, RNA1509_4992, RNA815_4037.1} |
16. | MligTC455_20400 | 4609 | 96.03 | Mlig455_007551, Mlig455_011814 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.242 Region-enriched R7: 5.211/0.00000 Regeneration-downregulated BL: -6.608 Regeneration-depleted BL: -6.608 |
1.728 | - | 0.955 | 0.773 | - | - | - | Mlig455_007551 {REF} {Length: 486} {RNA1509_8862} {RNA1310_107754, RNA1509_8862} {RNA1509_8862, RNA815_47935} Mlig455_011814 {REF} {Length: 367} {RNA1509_8862} {RNA1310_107754} {RNA815_47935} |
|
17. | MligTC455_28650 | 110 | 2.28 | Mlig455_048259 | Neo: - Age: Down-Down-Up |
RNF213 | 0.956 | - | - | - | - | - | 0.956 | Mlig455_048259 {REF} {Length: 11132} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=26.0]; AAA domain (dynein-related subfamily) [PF07728.16, score=23.9]} {Human: ENSG00000173821, RNF213, ring finger protein 213, [Score=342, Expect=3e-93]} {Mouse: ENSMUSG00000070327, Rnf213, ring finger protein 213, [Score=337, Expect=6e-92]} {RNA1509_34013} {RNA1310_20549} {RNA815_15} |
18. | MligTC455_09864 | 83 | 1.72 | Mlig455_018074 | Neo: - Age: - |
0.953 | - | - | - | - | - | 0.953 | Mlig455_018074 {REF} {Length: 1002} {RNA1310_103372} | |
19. | MligTC455_28649 | 93 | 1.94 | Mlig455_048260 | Neo: - Age: - |
TRPM3 | 0.95 | - | - | - | - | - | 0.950 | Mlig455_048260 {REF} {Length: 6001} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=77.0]; Ankyrin repeat [PF13606.8, score=68.0]; Ankyrin repeats (many copies) [PF13637.8, score=66.3]; Ankyrin repeat [PF00023.32, score=56.2]; Ion transport protein [PF00520.33, score=53.5]; Ankyrin repeats (many copies) [PF13857.8, score=45.8]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=158, Expect=2e-38]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=162, Expect=1e-39]} {Dmel: FBgn0005614, trpl, transient receptor potential-like, [Score=80.1, Expect=1e-14]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=106, Expect=8e-23]} {Smed: dd_Smed_v6_8382_0_1, dd_Smed_v6_8382_0_1, [Score=194, Expect=4e-50]} {RNA1509_8039} {RNA1310_1471} {RNA815_562} |