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Results for MligTC455_30837

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_30837 263 5.48 Mlig455_061238

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.646

TRPM3 Mlig455_061238 {REF} {Length: 10040} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=99.8, Expect=1e-20]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=100, Expect=4e-21]; ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [Score=95.5, Expect=1e-19]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=91.3, Expect=2e-18]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=74.7, Expect=2e-13]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=118, Expect=3e-27]} {RNA1509_26663} {RNA1310_1128.1, RNA1509_26663} {RNA1509_26663, RNA815_4971}

Cumulative graph for MligTC455_30837

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -5.004 2.513 0.28949 0.94131
RegionR2 2.413 2.513 0.00844 0.09056
RegionR3 1.797 2.513 0.03494 0.32391
RegionR4 0.76 2.513 0.49308 0.81971
RegionR5 0.126 2.513 0.81178 1.00000
RegionR6 -0.381 2.513 0.94327 1.00000
RegionR7 0.998 2.513 0.42635 1.00000
RegionR8 -0.708 2.513 0.97630 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 6.596 2.513 0.10675 0.82884
RegenerationR2 -0.931 2.513 0.12432 0.54606
RegenerationR3 -1.054 2.513 0.11421 0.52799
RegenerationR4 -0.587 2.513 0.45006 0.84183
RegenerationR5 -0.785 2.513 0.33023 0.75178
RegenerationR6 1.19 2.513 0.15546 0.48205
RegenerationBL 0.789 2.513 0.44019 0.80711
RegenerationTP 0.992 2.513 0.39514 0.82594


Genes with expression patterns similar to MligTC455_30837

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_30837 263 5.48 Mlig455_061238

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.646

TRPM3 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_061238 {REF} {Length: 10040} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=99.8, Expect=1e-20]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=100, Expect=4e-21]; ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [Score=95.5, Expect=1e-19]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=91.3, Expect=2e-18]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=74.7, Expect=2e-13]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=118, Expect=3e-27]} {RNA1509_26663} {RNA1310_1128.1, RNA1509_26663} {RNA1509_26663, RNA815_4971}
2. MligTC455_17738 600 12.49 Mlig455_005267

Neo: -

Age: Up-Down-Up

PKNOX2 2.567 - 0.850 0.746 0.971 - - Mlig455_005267 {REF} {Length: 4191} {Pfam: Homeobox KN domain [PF05920.13, score=68.1]; N-terminal of Homeobox Meis and PKNOX1 [PF16493.7, score=55.5]; Homeodomain [PF00046.31, score=30.5]} {Human: ENSG00000165495, PKNOX2, PBX/knotted 1 homeobox 2, [RH, Score=209, Expect=1e-59]} {Mouse: ENSMUSG00000035934, Pknox2, Pbx/knotted 1 homeobox 2, [RH, Score=209, Expect=2e-59]} {Dmel: FBgn0001235, hth, homothorax, [Score=117, Expect=1e-27]} {Celegans: WBGene00006796, unc-62, Homeobox protein unc-62, [Score=107, Expect=3e-24]} {Smed: dd_Smed_v6_8606_0_1, dd_Smed_v6_8606_0_1, [Score=258, Expect=2e-75]} {RNA1509_58890} {RNA1310_1426.1} {RNA815_7214}
3. MligTC455_32839 282 5.88 Mlig455_048680

Neo: -

Age: logFC(26M/2M)=-0.401

IFT52 2.518 - - 0.806 0.982 - 0.730 Mlig455_048680 {REF} {Length: 2593} {TRANSSPLICED} {Pfam: ABC-type uncharacterized transport system [PF09822.11, score=30.3]} {Human: ENSG00000101052, IFT52, intraflagellar transport 52, [RH, Score=518, Expect=0.0]} {Mouse: ENSMUSG00000017858, Ift52, intraflagellar transport 52, [RH, Score=532, Expect=0.0]} {Dmel: FBgn0031829, IFT52, Intraflagellar transport 52, [RH, Score=282, Expect=1e-90]} {Celegans: WBGene00003886, osm-6, Osm-6 protein, [RH, Score=305, Expect=6e-99]} {Smed: dd_Smed_v6_5043_0_1, dd_Smed_v6_5043_0_1, [RH, Score=537, Expect=0.0]} {RNA1509_8537} {RNA1310_16849} {RNA815_7203}
4. MligTC455_33552 905 18.86 Mlig455_014406, Mlig455_070160

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.705/0.03873

KCNH1 2.511 0.790 0.724 - 0.997 - -

Mlig455_014406 {REF} {Length: 5774} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=54.1]} {Human: ENSG00000143473, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=269, Expect=1e-82]; ENSG00000283965, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=269, Expect=1e-82]; ENSG00000140015, KCNH5, potassium voltage-gated channel subfamily H member 5, [Score=256, Expect=1e-74]} {Mouse: ENSMUSG00000058248, Kcnh1, potassium voltage-gated channel, subfamily H (eag-related), member 1, [Score=267, Expect=4e-79]; ENSMUSG00000034402, Kcnh5, potassium voltage-gated channel, subfamily H (eag-related), member 5, [Score=256, Expect=3e-75]} {Dmel: FBgn0000535, eag, ether a go-go, [Score=283, Expect=5e-84]} {Celegans: WBGene00001171, egl-2, EAG K+ channel EGL-2, [Score=240, Expect=1e-69]} {Smed: dd_Smed_v6_23063_0_1, dd_Smed_v6_23063_0_1, [Score=283, Expect=7e-86]} {RNA1509_16580} {RNA1310_9615} {RNA815_20522}

Mlig455_070160 {REF} {Length: 3641} {Pfam: Ion transport protein [PF00520.33, score=111.5]; Cyclic nucleotide-binding domain [PF00027.31, score=53.3]; Ion channel [PF07885.18, score=40.6]} {Human: ENSG00000143473, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=795, Expect=0.0]; ENSG00000283965, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=795, Expect=0.0]; ENSG00000140015, KCNH5, potassium voltage-gated channel subfamily H member 5, [Score=771, Expect=0.0]} {Mouse: ENSMUSG00000058248, Kcnh1, potassium voltage-gated channel, subfamily H (eag-related), member 1, [Score=794, Expect=0.0]; ENSMUSG00000034402, Kcnh5, potassium voltage-gated channel, subfamily H (eag-related), member 5, [Score=770, Expect=0.0]} {Dmel: FBgn0000535, eag, ether a go-go, [Score=838, Expect=0.0]} {Celegans: WBGene00001171, egl-2, EAG K+ channel EGL-2, [Score=688, Expect=0.0]} {Smed: dd_Smed_v6_18793_0_1, dd_Smed_v6_18793_0_1, [Score=895, Expect=0.0]} {RNA1509_16580} {RNA1310_6070} {RNA815_18231}
5. MligTC455_45822 733 15.27 Mlig455_030111, Mlig455_030180

Neo: -

Age: -

Region-enriched R4: 2.554/0.00328

2.42 0.705 - 0.749 0.966 - -

Mlig455_030111 {REF} {Length: 2896} {TRANSSPLICED} {Pfam: Mitotic-spindle organizing gamma-tubulin ring associated [PF12926.9, score=29.8]} {RNA1509_27378, RNA1509_41692} {RNA1310_18834, RNA1509_41692} {RNA1509_41692, RNA815_11733}

Mlig455_030180 {REF} {Length: 2897} {TRANSSPLICED} {Pfam: Mitotic-spindle organizing gamma-tubulin ring associated [PF12926.9, score=29.8]} {RNA1509_27378, RNA1509_49391} {RNA1310_18834, RNA1509_49391} {RNA1509_49391, RNA815_11733}
6. MligTC455_28851 635 13.22 Mlig455_015966, Mlig455_015985, Mlig455_016082, Mlig455_041037, Mlig455_051413, Mlig455_059417

Neo: -

Age: -

2.419 0.701 - 0.731 0.987 - -

Mlig455_015966 {REF} {Length: 4813} {RNA1509_34937} {RNA1310_2313.1} {RNA815_7759.1}

Mlig455_015985 {REF} {Length: 5033} {RNA1509_34937, RNA1509_37327} {RNA1310_2313.1, RNA1509_37327} {RNA1509_37327, RNA815_7759.1}

Mlig455_016082 {REF} {Length: 419} {NoTransDecoderORF} {RNA1509_34937} {RNA1310_3298} {RNA815_22311}

Mlig455_041037 {REF} {Length: 2026} {RNA1509_22642} {RNA1310_32012} {RNA815_16629}

Mlig455_051413 {REF} {Length: 3765} {RNA1509_34937, RNA1509_47681} {RNA1310_3298, RNA1509_47681} {RNA1509_47681, RNA815_7759.1}

Mlig455_059417 {REF} {Length: 3670} {RNA1509_34937} {RNA1310_2313.1} {RNA815_7759.1}
7. MligTC455_43329 235 4.9 Mlig455_007154

Neo: -

Age: -

Region-enriched R2: 3.268/0.02528
Region-enriched R5: 2.289/0.03532

SMURF2 1.923 - - 0.930 0.993 - - Mlig455_007154 {REF} {Length: 4687} {Pfam: HECT-domain (ubiquitin-transferase) [PF00632.27, score=303.1]; WW domain [PF00397.28, score=64.2]} {Human: ENSG00000108854, SMURF2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=636, Expect=0.0]} {Mouse: ENSMUSG00000018363, Smurf2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=637, Expect=0.0]} {Dmel: FBgn0259174, Nedd4, [Score=409, Expect=4e-133]} {Celegans: WBGene00022358, Y92H12A.2, E3 ubiquitin-protein ligase, [Score=400, Expect=2e-133]} {Smed: dd_Smed_v6_7322_0_1, dd_Smed_v6_7322_0_1, [Score=398, Expect=2e-128]} {RNA1509_42014} {RNA1310_6371} {RNA815_17584}
8. MligTC455_37160 1139 23.73 Mlig455_015317, Mlig455_032998, Mlig455_068744

Neo: -

Age: logFC(26M/2M)=-0.355

Region-enriched R2: 1.560/0.01222

TTC28 1.902 - - - 0.980 0.922 -

Mlig455_015317 {REF} {Length: 5958} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=63.4]; Tetratricopeptide repeat [PF07719.19, score=51.3]; Tetratricopeptide repeat [PF00515.30, score=40.4]; Tetratricopeptide repeat [PF13181.8, score=39.5]; CHAT domain [PF12770.9, score=37.9]; Tetratricopeptide repeat [PF14559.8, score=23.5]; Tetratricopeptide repeat [PF13431.8, score=22.4]; Tetratricopeptide repeat [PF13176.8, score=20.4]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=69.3, Expect=7e-11]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=70.9, Expect=2e-11]} {RNA1509_5411} {RNA1310_761.1} {RNA815_600}

Mlig455_032998 {REF} {Length: 5728} {Pfam: CHAT domain [PF12770.9, score=39.2]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=67.8, Expect=1e-10]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=69.3, Expect=3e-11]} {RNA1509_5411} {RNA1310_761.1} {RNA815_600}

Mlig455_068744 {REF} {Length: 5980} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=62.6]; Tetratricopeptide repeat [PF07719.19, score=49.0]; Tetratricopeptide repeat [PF13181.8, score=39.3]; Tetratricopeptide repeat [PF00515.30, score=38.4]; CHAT domain [PF12770.9, score=37.8]; Tetratricopeptide repeat [PF14559.8, score=22.1]; Tetratricopeptide repeat [PF13431.8, score=20.8]; Tetratricopeptide repeat [PF13176.8, score=19.2]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=66.2, Expect=6e-10]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=67.8, Expect=1e-10]} {RNA1509_5411} {RNA1310_761.2} {RNA815_600}
9. MligTC455_15974 179 3.73 Mlig455_046153, Mlig455_046238

Neo: -

Age: -

Region-enriched R2: 9.367/0.02495

1.896 0.900 - - 0.996 - -

Mlig455_046153 {REF} {Length: 345} {Pfam: Pancreatic hormone peptide [PF00159.20, score=36.0]} {RNA1310_79109} {RNA815_46493}

Mlig455_046238 {REF} {Length: 211} {NoTransDecoderORF} {RNA1310_79109} {RNA815_46493}
10. MligTC455_26666 497 10.35 Mlig455_014576

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.303

CNBD2 1.894 - - - 0.992 0.902 - Mlig455_014576 {REF} {Length: 3147} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=74.1]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [RH, Score=97.8, Expect=2e-20]} {Mouse: ENSMUSG00000038085, Cnbd2, cyclic nucleotide binding domain containing 2, [RH, Score=86.3, Expect=3e-17]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [Score=58.2, Expect=9e-09]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=62.0, Expect=5e-10]} {Smed: dd_Smed_v6_15589_0_1, dd_Smed_v6_15589_0_1, [RH, Score=451, Expect=2e-148]} {RNA1509_14495, RNA1509_43806} {RNA1310_6298, RNA1509_43806} {RNA1509_43806, RNA815_2010}
11. MligTC455_39222 213 4.44 Mlig455_064653, Mlig455_064686

Neo: -

Age: -

Region-enriched R2: 4.317/0.00597

1.874 0.883 - - 0.991 - -

Mlig455_064653 {REF} {Length: 2836} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.9, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=7e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_56255} {RNA1310_13407} {RNA815_38407}

Mlig455_064686 {REF} {Length: 3820} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.5, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=8e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_50956} {RNA1310_13407} {RNA815_38407}
12. MligTC455_44643 536 11.17 Mlig455_070222

Neo: -

Age: -

1.871 - - - 0.974 - 0.897 Mlig455_070222 {REF} {Length: 1253} {RNA1509_59785} {RNA1310_13499.1} {RNA815_8470}
13. MligTC455_20170 849 17.7 Mlig455_014217, Mlig455_070573

Neo: -

Age: Down-Up-Down

1.865 - - - 0.988 0.877 -

Mlig455_014217 {REF} {Length: 3033} {RNA1509_39863} {RNA1310_22305, RNA1509_39863} {RNA1509_39863, RNA815_5167}

Mlig455_070573 {REF} {Length: 2251} {RNA1509_37573} {RNA1310_17580} {RNA815_5167}
14. MligTC455_32970 882 18.38 Mlig455_036420

Neo: -

Age: logFC(26M/2M)=0.322

ESRRA 1.854 - - - 0.984 - 0.870 Mlig455_036420 {REF} {Length: 3551} {TRANSSPLICED} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=97.6]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=20.3]} {Human: ENSG00000173153, ESRRA, estrogen related receptor alpha, [RH, Score=156, Expect=1e-41]} {Mouse: ENSMUSG00000024955, Esrra, estrogen related receptor, alpha, [RH, Score=155, Expect=2e-41]} {Dmel: FBgn0035849, ERR, estrogen-related receptor, [RH, Score=150, Expect=2e-39]} {Celegans: WBGene00003630, nhr-40, Nuclear hormone receptor family member nhr-40, [RH, Score=120, Expect=2e-29]} {Smed: dd_Smed_v6_7551_0_1, dd_Smed_v6_7551_0_1, [Score=110, Expect=3e-25]} {RNA1509_13075, RNA1509_49940, RNA1509_7347} {RNA1310_9409, RNA1509_13075, RNA1509_49940, RNA1509_7347} {RNA1509_13075, RNA1509_49940, RNA1509_7347, RNA815_7739}
15. MligTC455_19324 1062 22.13 Mlig455_045112

Neo: Int S/G2/M

Age: -

KCTD21 1.834 - - - 0.974 0.860 - Mlig455_045112 {REF} {Length: 1839} {TRANSSPLICED} {Pfam: BTB/POZ domain [PF02214.24, score=57.7]; N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) [PF07221.13, score=18.0]} {Human: ENSG00000188997, KCTD21, potassium channel tetramerization domain containing 21, [RH, Score=102, Expect=7e-27]} {Mouse: ENSMUSG00000044952, Kctd21, potassium channel tetramerisation domain containing 21, [RH, Score=103, Expect=4e-26]} {Dmel: FBgn0038839, Ktl, Kctd12-like, [Score=86.7, Expect=4e-20]} {Celegans: WBGene00014848, VM106R.1, [Score=82.4, Expect=4e-18]} {Smed: dd_Smed_v6_8654_0_1, dd_Smed_v6_8654_0_1, [RH, Score=192, Expect=5e-61]} {RNA1509_8015} {RNA1310_35464.2} {RNA815_25284}
16. MligTC455_47601 126 2.62 Mlig455_056477

Neo: -

Age: Up-Down-Up

NRXN1 1.833 0.861 - - 0.972 - - Mlig455_056477 {REF} {Length: 3481} {Pfam: Laminin G domain [PF02210.26, score=58.3]; Laminin G domain [PF00054.25, score=43.2]; Syndecan domain [PF01034.22, score=27.4]} {Human: ENSG00000179915, NRXN1, neurexin 1, [Score=142, Expect=4e-35]} {Mouse: ENSMUSG00000024109, Nrxn1, neurexin I, [Score=142, Expect=1e-35]} {Dmel: FBgn0038975, Nrx-1, Neurexin 1, [Score=102, Expect=2e-22]} {Smed: dd_Smed_v6_13697_0_1, dd_Smed_v6_13697_0_1, [Score=142, Expect=8e-36]} {RNA1509_55888} {RNA1310_37025, RNA1509_55888} {RNA1509_55888, RNA815_22404}
17. MligTC455_17737 522 10.87 Mlig455_005002

Neo: -

Age: -

1.824 - 0.851 - 0.973 - - Mlig455_005002 {REF} {Length: 982} {NoTransDecoderORF} {RNA1310_1426.1} {RNA815_30413}
18. MligTC455_18590 632 13.16 Mlig455_006915, Mlig455_017931

Neo: -

Age: -

Region-enriched R3: 3.002/0.00887
Region-enriched R5: 2.798/0.00397

SLC25A37 1.82 - - 0.836 0.984 - -

Mlig455_006915 {REF} {Length: 3466} {TRANSSPLICED} {Pfam: Mitochondrial carrier protein [PF00153.29, score=192.6]} {Human: ENSG00000147454, SLC25A37, solute carrier family 25 member 37, [RH, Score=321, Expect=1e-108]} {Mouse: ENSMUSG00000034248, Slc25a37, solute carrier family 25, member 37, [RH, Score=315, Expect=1e-106]; ENSMUSG00000040414, Slc25a28, solute carrier family 25, member 28, [RH, Score=305, Expect=3e-102]} {Dmel: FBgn0039561, mfrn, mitoferrin, [RH, Score=263, Expect=6e-86]} {Celegans: WBGene00012204, mfn-1, Mitoferrin, [RH, Score=257, Expect=3e-84]} {Smed: dd_Smed_v6_11061_0_1, dd_Smed_v6_11061_0_1, [RH, Score=317, Expect=5e-108]} {RNA1509_40499} {RNA1310_19207} {RNA815_13306}

Mlig455_017931 {REF} {Length: 3454} {TRANSSPLICED} {Pfam: Mitochondrial carrier protein [PF00153.29, score=192.6]} {Human: ENSG00000147454, SLC25A37, solute carrier family 25 member 37, [RH, Score=321, Expect=1e-108]} {Mouse: ENSMUSG00000034248, Slc25a37, solute carrier family 25, member 37, [RH, Score=315, Expect=1e-106]; ENSMUSG00000040414, Slc25a28, solute carrier family 25, member 28, [RH, Score=305, Expect=3e-102]} {Dmel: FBgn0039561, mfrn, mitoferrin, [RH, Score=263, Expect=6e-86]} {Celegans: WBGene00012204, mfn-1, Mitoferrin, [RH, Score=257, Expect=3e-84]} {Smed: dd_Smed_v6_11061_0_1, dd_Smed_v6_11061_0_1, [RH, Score=317, Expect=5e-108]} {RNA1509_21388, RNA1509_36168, RNA1509_40499, RNA1509_48571, RNA1509_57782} {RNA1310_19207, RNA1509_21388, RNA1509_36168, RNA1509_40499, RNA1509_48571, RNA1509_57782} {RNA1509_21388, RNA1509_36168, RNA1509_40499, RNA1509_48571, RNA1509_57782, RNA815_13306}
19. MligTC455_29167 831 17.3 Mlig455_000398

Neo: -

Age: Up-Down-Down

DNAH5 1.818 - - - 0.950 0.868 - Mlig455_000398 {REF} {Length: 14585} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=581.1]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=469.7]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=434.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=319.5]; P-loop containing dynein motor region D4 [PF12780.9, score=304.5]; ATP-binding dynein motor region [PF12781.9, score=284.2]; P-loop containing dynein motor region [PF12775.9, score=230.3]; Dynein heavy chain AAA lid domain [PF18198.3, score=176.9]; Microtubule-binding stalk of dynein motor [PF12777.9, score=135.9]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=120.1]; AAA domain (dynein-related subfamily) [PF07728.16, score=80.3]; Dynein heavy chain AAA lid domain [PF17852.3, score=66.4]; AAA+ lid domain [PF17857.3, score=62.9]; AAA ATPase domain [PF13191.8, score=24.5]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=23.0]; AAA domain [PF13401.8, score=20.7]; BRE1 E3 ubiquitin ligase [PF08647.13, score=19.9]; P-loop containing region of AAA domain [PF13555.8, score=19.7]} {Human: ENSG00000039139, DNAH5, dynein axonemal heavy chain 5, [RH, Score=6261, Expect=0.0]} {Mouse: ENSMUSG00000022262, Dnah5, dynein, axonemal, heavy chain 5, [RH, Score=6235, Expect=0.0]} {Dmel: FBgn0037726, CG9492, [RH, Score=5129, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=1287, Expect=0.0]} {Smed: dd_Smed_v6_4569_0_1, dd_Smed_v6_4569_0_1, [RH, Score=6966, Expect=0.0]} {RNA1509_653} {RNA1310_37.1} {RNA815_534.1}
20. MligTC455_21740 254 5.3 Mlig455_008034, Mlig455_008071

Neo: -

Age: Up-Down-Up

CCDC150 1.809 - - 0.813 0.996 - -

Mlig455_008034 {REF} {Length: 3802} {TRANSSPLICED} {Human: ENSG00000144395, CCDC150, coiled-coil domain containing 150, [Score=80.1, Expect=1e-14]} {Mouse: ENSMUSG00000025983, Ccdc150, coiled-coil domain containing 150, [Score=76.6, Expect=1e-13]} {RNA1509_19254} {RNA1310_9574} {RNA815_22339}

Mlig455_008071 {REF} {Length: 3867} {TRANSSPLICED} {Human: ENSG00000144395, CCDC150, coiled-coil domain containing 150, [Score=79.7, Expect=2e-14]} {Mouse: ENSMUSG00000025983, Ccdc150, coiled-coil domain containing 150, [Score=76.6, Expect=1e-13]} {RNA1509_19254} {RNA1310_9574, RNA1509_19254} {RNA1509_19254, RNA815_22339}
21. MligTC455_47977 1528 31.83 Mlig455_060791, Mlig455_060820

Neo: Int S/G2/M

Age: -

FARSA 1.808 - - 0.835 0.973 - -

Mlig455_060791 {REF} {Length: 2199} {Pfam: tRNA synthetases class II core domain (F) [PF01409.22, score=307.5]; PheRS DNA binding domain 3 [PF18553.3, score=68.2]; PheRS DNA binding domain 1 [PF18552.3, score=56.3]; PheRS DNA binding domain 2 [PF18554.3, score=29.9]; Phenylalanyl tRNA synthetase beta chain CLM domain [PF17759.3, score=24.2]; tRNA synthetases class II (D, K and N) [PF00152.22, score=21.0]} {Human: ENSG00000179115, FARSA, phenylalanyl-tRNA synthetase subunit alpha, [RH, Score=652, Expect=0.0]} {Mouse: ENSMUSG00000003808, Farsa, phenylalanyl-tRNA synthetase, alpha subunit, [RH, Score=654, Expect=0.0]} {Dmel: FBgn0030007, alpha-PheRS, Phenylalanyl-tRNA synthetase, alpha-subunit, [RH, Score=619, Expect=0.0]} {Celegans: WBGene00001497, fars-1, Phenylalanyl Amino-acyl tRNA Synthetase, [RH, Score=596, Expect=0.0]} {Smed: dd_Smed_v6_3224_0_1, dd_Smed_v6_3224_0_1, [RH, Score=516, Expect=0.0]} {RNA1509_4587} {RNA1310_10271.1, RNA1509_4587} {RNA1509_4587, RNA815_6726}

Mlig455_060820 {REF} {Length: 2416} {Pfam: tRNA synthetases class II core domain (F) [PF01409.22, score=307.5]; PheRS DNA binding domain 3 [PF18553.3, score=67.2]; PheRS DNA binding domain 1 [PF18552.3, score=56.3]; PheRS DNA binding domain 2 [PF18554.3, score=29.9]; Phenylalanyl tRNA synthetase beta chain CLM domain [PF17759.3, score=24.2]; tRNA synthetases class II (D, K and N) [PF00152.22, score=21.0]} {Human: ENSG00000179115, FARSA, phenylalanyl-tRNA synthetase subunit alpha, [RH, Score=652, Expect=0.0]} {Mouse: ENSMUSG00000003808, Farsa, phenylalanyl-tRNA synthetase, alpha subunit, [RH, Score=653, Expect=0.0]} {Dmel: FBgn0030007, alpha-PheRS, Phenylalanyl-tRNA synthetase, alpha-subunit, [RH, Score=618, Expect=0.0]} {Celegans: WBGene00001497, fars-1, Phenylalanyl Amino-acyl tRNA Synthetase, [RH, Score=595, Expect=0.0]} {Smed: dd_Smed_v6_3224_0_1, dd_Smed_v6_3224_0_1, [RH, Score=515, Expect=1e-180]} {RNA1509_40184} {RNA1310_10271.2, RNA1509_40184} {RNA1509_40184, RNA815_6726}
22. MligTC455_50326 349 7.27 Mlig455_000563, Mlig455_030362

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.949/0.00096

ARID3A 1.808 - 0.833 - 0.975 - -

Mlig455_000563 {REF} {Length: 2916} {Pfam: ARID/BRIGHT DNA binding domain [PF01388.23, score=72.3]} {Human: ENSG00000116017, ARID3A, AT-rich interaction domain 3A, [RH, Score=244, Expect=4e-74]; ENSG00000205143, ARID3C, AT-rich interaction domain 3C, [RH, Score=244, Expect=5e-73]; ENSG00000179361, ARID3B, AT-rich interaction domain 3B, [RH, Score=236, Expect=3e-68]} {Mouse: ENSMUSG00000019564, Arid3a, AT rich interactive domain 3A (BRIGHT-like), [RH, Score=247, Expect=3e-72]; ENSMUSG00000066224, Arid3c, AT rich interactive domain 3C (BRIGHT-like), [RH, Score=247, Expect=2e-74]; ENSMUSG00000004661, Arid3b, AT rich interactive domain 3B (BRIGHT-like), [RH, Score=235, Expect=4e-68]} {Dmel: FBgn0004795, retn, retained, [RH, Score=244, Expect=7e-69]} {Celegans: WBGene00000476, cfi-1, AT-rich interactive domain-containing protein cfi-1, [RH, Score=229, Expect=6e-67]} {Smed: dd_Smed_v6_13474_0_1, dd_Smed_v6_13474_0_1, [RH, Score=257, Expect=3e-76]} {RNA1310_43081} {RNA815_22524}

Mlig455_030362 {REF} {Length: 2929} {Pfam: ARID/BRIGHT DNA binding domain [PF01388.23, score=72.3]} {Human: ENSG00000116017, ARID3A, AT-rich interaction domain 3A, [RH, Score=241, Expect=9e-73]; ENSG00000205143, ARID3C, AT-rich interaction domain 3C, [RH, Score=241, Expect=6e-72]; ENSG00000179361, ARID3B, AT-rich interaction domain 3B, [RH, Score=233, Expect=4e-67]} {Mouse: ENSMUSG00000066224, Arid3c, AT rich interactive domain 3C (BRIGHT-like), [RH, Score=244, Expect=1e-73]; ENSMUSG00000019564, Arid3a, AT rich interactive domain 3A (BRIGHT-like), [RH, Score=243, Expect=7e-71]; ENSMUSG00000004661, Arid3b, AT rich interactive domain 3B (BRIGHT-like), [RH, Score=232, Expect=6e-67]} {Dmel: FBgn0004795, retn, retained, [RH, Score=240, Expect=1e-67]} {Celegans: WBGene00000476, cfi-1, AT-rich interactive domain-containing protein cfi-1, [RH, Score=229, Expect=5e-67]} {Smed: dd_Smed_v6_13474_0_1, dd_Smed_v6_13474_0_1, [RH, Score=258, Expect=2e-76]} {RNA1310_43081} {RNA815_22524}
23. MligTC455_14328 585 12.19 Mlig455_035956, Mlig455_058425

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=3.032

Region-enriched R2: 6.210/0.01234
Region-enriched R3: 5.834/0.00211

CYP2U1 1.795 - - 0.817 0.978 - -

Mlig455_035956 {REF} {Length: 4315} {Pfam: Cytochrome P450 [PF00067.24, score=301.9]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=213, Expect=5e-62]; ENSG00000108242, CYP2C18, cytochrome P450 family 2 subfamily C member 18, [Score=205, Expect=9e-60]} {Mouse: ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [Score=215, Expect=9e-64]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [Score=214, Expect=3e-63]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=213, Expect=2e-62]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=213, Expect=2e-62]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=212, Expect=2e-62]; ENSMUSG00000052974, Cyp2f2, cytochrome P450, family 2, subfamily f, polypeptide 2, [Score=208, Expect=5e-61]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=179, Expect=5e-50]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=206, Expect=3e-60]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [Score=226, Expect=7e-68]} {RNA1509_49553} {RNA1310_2911.1} {RNA815_12179}

Mlig455_058425 {REF} {Length: 2850} {Pfam: Cytochrome P450 [PF00067.24, score=301.9]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=213, Expect=5e-62]; ENSG00000108242, CYP2C18, cytochrome P450 family 2 subfamily C member 18, [Score=205, Expect=9e-60]} {Mouse: ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [Score=215, Expect=9e-64]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [Score=214, Expect=3e-63]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=213, Expect=2e-62]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=213, Expect=2e-62]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=212, Expect=2e-62]; ENSMUSG00000052974, Cyp2f2, cytochrome P450, family 2, subfamily f, polypeptide 2, [Score=208, Expect=5e-61]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=179, Expect=5e-50]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=206, Expect=3e-60]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [Score=226, Expect=7e-68]} {RNA1509_49553} {RNA1310_2911.1, RNA1509_49553} {RNA1509_49553, RNA815_12179}
24. MligTC455_26777 378 7.88 Mlig455_058623

Neo: -

Age: -

KDM8 1.786 - - 0.792 0.994 - - Mlig455_058623 {REF} {Length: 1880} {TRANSSPLICED} {Pfam: Cupin-like domain [PF13621.8, score=140.2]} {Human: ENSG00000155666, KDM8, lysine demethylase 8, [RH, Score=264, Expect=3e-84]} {Mouse: ENSMUSG00000030752, Kdm8, lysine (K)-specific demethylase 8, [RH, Score=259, Expect=1e-82]} {Dmel: FBgn0035166, CG13902, [RH, Score=201, Expect=3e-60]} {Celegans: WBGene00007387, jmjd-5, JuMonJi (Transcription factor) Domain protein, [RH, Score=216, Expect=1e-64]} {Smed: dd_Smed_v6_5363_0_1, dd_Smed_v6_5363_0_1, [RH, Score=238, Expect=8e-75]} {RNA1509_33307} {RNA1310_14967} {RNA815_36817}
25. MligTC455_54126 566 11.79 Mlig455_000053

Neo: -

Age: -

SPEF1 1.785 - - - 0.984 0.801 - Mlig455_000053 {REF} {Length: 1286} {TRANSSPLICED} {Pfam: CH-like domain in sperm protein [PF06294.13, score=114.7]; CAMSAP CH domain [PF11971.10, score=53.6]} {Human: ENSG00000101222, SPEF1, sperm flagellar 1, [RH, Score=172, Expect=1e-52]} {Mouse: ENSMUSG00000027329, Spef1, sperm flagellar 1, [RH, Score=180, Expect=3e-56]} {Dmel: FBgn0030722, CG12395, [Score=65.5, Expect=2e-12]} {Smed: dd_Smed_v6_5648_0_1, dd_Smed_v6_5648_0_1, [RH, Score=272, Expect=5e-93]} {RNA1509_48542} {RNA1310_25346.2} {RNA815_11607}
26. MligTC455_42112 216 4.5 Mlig455_012680

Neo: -

Age: Down-Down-Up

1.778 - 0.783 - 0.995 - - Mlig455_012680 {REF} {Length: 1838} {Pfam: Glycosyltransferase family 92 [PF01697.29, score=87.6]} {Dmel: FBgn0032506, CG9395, [Score=83.2, Expect=2e-16]} {Smed: dd_Smed_v6_5401_0_1, dd_Smed_v6_5401_0_1, [Score=205, Expect=6e-61]} {RNA1310_16265} {RNA815_5740.1}
27. MligTC455_41854 80 1.67 Mlig455_034307, Mlig455_067305, Mlig455_067321

Neo: -

Age: -

1.777 0.967 0.810 - - - -

Mlig455_034307 {REF} {Length: 459} {RNA815_51696.1}

Mlig455_067305 {REF} {Length: 466} {RNA815_51696.1}

Mlig455_067321 {REF} {Length: 95} {TRANSSPLICED} {NoTransDecoderORF} {RNA815_51696.1}
28. MligTC455_19586 643 13.4 Mlig455_064120, Mlig455_068981

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.075

Region-enriched R2: 4.002/0.00535

1.774 - 0.781 - 0.993 - -

Mlig455_064120 {REF} {Length: 2223} {RNA1509_22549, RNA1509_44981} {RNA1310_41406.1, RNA1509_22549, RNA1509_44981} {RNA1509_22549, RNA1509_44981, RNA815_17251}

Mlig455_068981 {REF} {Length: 1510} {RNA1509_44981} {RNA1310_41406.1} {RNA815_17251}
29. MligTC455_32133 781 16.27 Mlig455_051306

Neo: -

Age: logFC(26M/2M)=-0.416

Region-enriched R8: 2.021/0.00643

ANKRD63 1.764 - - - 0.957 0.807 - Mlig455_051306 {REF} {Length: 3343} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=60.9]; Ankyrin repeats (many copies) [PF13637.8, score=56.5]; Ankyrin repeats (many copies) [PF13857.8, score=51.2]; Ankyrin repeat [PF00023.32, score=50.5]; Ankyrin repeat [PF13606.8, score=45.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.2]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [Score=73.6, Expect=2e-13]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [Score=71.6, Expect=5e-13]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=58.2, Expect=2e-08]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=57.0, Expect=3e-08]} {Smed: dd_Smed_v6_11079_0_1, dd_Smed_v6_11079_0_1, [RH, Score=112, Expect=4e-27]} {RNA1509_19755} {RNA1310_3218.1} {RNA815_26964}
30. MligTC455_36264 546 11.38 Mlig455_022401

Neo: -

Age: Down-Up-Up

THG1L 1.764 - - 0.779 0.985 - - Mlig455_022401 {REF} {Length: 2292} {TRANSSPLICED} {Pfam: tRNAHis guanylyltransferase [PF04446.14, score=155.3]; Thg1 C terminal domain [PF14413.8, score=153.0]; Protein kinase domain [PF00069.27, score=126.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=82.0]} {Human: ENSG00000113272, THG1L, tRNA-histidine guanylyltransferase 1 like, [RH, Score=308, Expect=3e-100]} {Mouse: ENSMUSG00000011254, Thg1l, tRNA-histidine guanylyltransferase 1-like (S. cerevisiae), [RH, Score=308, Expect=2e-100]} {Dmel: FBgn0283659, THG, tRNA-histidine guanylyltransferase, [RH, Score=277, Expect=1e-88]} {Celegans: WBGene00008424, D2045.7, [RH, Score=129, Expect=6e-33]} {Smed: dd_Smed_v6_14422_0_2, dd_Smed_v6_14422_0_2, [RH, Score=253, Expect=2e-80]} {RNA1509_22817} {RNA1310_33867.1} {RNA815_2617}
31. MligTC455_53549 782 16.29 Mlig455_059223

Neo: -

Age: Down-Down-Up

SIDT1 1.762 - - - 0.991 - 0.771 Mlig455_059223 {REF} {Length: 3659} {TRANSSPLICED} {Pfam: dsRNA-gated channel SID-1 [PF13965.8, score=293.6]} {Human: ENSG00000072858, SIDT1, SID1 transmembrane family member 1, [Score=169, Expect=2e-42]} {Mouse: ENSMUSG00000022696, Sidt1, SID1 transmembrane family, member 1, [Score=158, Expect=4e-39]; ENSMUSG00000034908, Sidt2, SID1 transmembrane family, member 2, [Score=154, Expect=7e-38]} {Celegans: WBGene00006477, chup-1, CHolesterol UPtake associated, [Score=118, Expect=6e-27]} {Smed: dd_Smed_v6_6063_0_2, dd_Smed_v6_6063_0_2, [Score=162, Expect=7e-41]} {RNA1509_26791} {RNA1310_31149.1} {RNA815_1905}
32. MligTC455_18882 322 6.71 Mlig455_067755

Neo: -

Age: -

1.761 - - 0.773 0.988 - - Mlig455_067755 {REF} {Length: 2949} {Pfam: TIR domain [PF13676.8, score=89.7]; TIR domain [PF01582.22, score=43.6]} {Smed: dd_Smed_v6_9201_0_1, dd_Smed_v6_9201_0_1, [RH, Score=303, Expect=2e-90]} {RNA1509_17089} {RNA1310_6087.1} {RNA815_12761}
33. MligTC455_48868 198 4.12 Mlig455_057233

Neo: -

Age: -

CAPS2 1.76 - - - 0.977 - 0.783 Mlig455_057233 {REF} {Length: 3222} {TRANSSPLICED} {Human: ENSG00000180881, CAPS2, calcyphosine 2, [RH, Score=207, Expect=4e-60]} {Mouse: ENSMUSG00000035694, Caps2, calcyphosphine 2, [RH, Score=225, Expect=6e-65]} {Dmel: FBgn0051345, CG31345, [Score=63.5, Expect=4e-11]} {Smed: dd_Smed_v6_7209_0_1, dd_Smed_v6_7209_0_1, [Score=72.0, Expect=3e-14]} {RNA1509_44692} {RNA1310_9646.1} {RNA815_2138.1}
34. MligTC455_39609 1749 36.43 Mlig455_046586

Neo: -

Age: logFC(26M/2M)=-0.358

APLP2 1.759 - - - 0.987 - 0.772 Mlig455_046586 {REF} {Length: 3742} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=48.2]; E2 domain of amyloid precursor protein [PF12925.9, score=41.5]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=41.0]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=40.4]} {Human: ENSG00000084234, APLP2, amyloid beta precursor like protein 2, [RH, Score=91.3, Expect=2e-18]} {Mouse: ENSMUSG00000031996, Aplp2, amyloid beta (A4) precursor-like protein 2, [RH, Score=84.3, Expect=2e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=87.8, Expect=1e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=103, Expect=1e-22]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=136, Expect=9e-34]} {RNA1509_2244, RNA1509_39752, RNA1509_42750, RNA1509_52555} {RNA1310_3149.1, RNA1509_39752, RNA1509_42750, RNA1509_52555} {RNA1509_39752, RNA1509_42750, RNA1509_52555, RNA815_958.1}
35. MligTC455_49623 1254 26.13 Mlig455_005003, Mlig455_005044, Mlig455_005273

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.089/0.03938

MAPRE1 1.754 - - - 0.970 0.784 -

Mlig455_005003 {REF} {Length: 1466} {TRANSSPLICED} {Pfam: EB1-like C-terminal motif [PF03271.19, score=48.5]; Calponin homology (CH) domain [PF00307.33, score=45.4]} {Human: ENSG00000101367, MAPRE1, microtubule associated protein RP/EB family member 1, [RH, Score=256, Expect=1e-84]; ENSG00000084764, MAPRE3, microtubule associated protein RP/EB family member 3, [RH, Score=247, Expect=5e-81]} {Mouse: ENSMUSG00000027479, Mapre1, microtubule-associated protein, RP/EB family, member 1, [RH, Score=255, Expect=2e-84]; ENSMUSG00000029166, Mapre3, microtubule-associated protein, RP/EB family, member 3, [RH, Score=244, Expect=5e-80]} {Dmel: FBgn0027066, Eb1, [RH, Score=258, Expect=1e-85]} {Celegans: WBGene00013344, ebp-1, Microtubule End Binding Protein, [RH, Score=218, Expect=2e-69]} {Smed: dd_Smed_v6_1322_0_2, dd_Smed_v6_1322_0_2, [RH, Score=309, Expect=3e-105]} {RNA1509_15908} {RNA1310_22066} {RNA815_24384}

Mlig455_005044 {REF} {Length: 1464} {TRANSSPLICED} {Pfam: EB1-like C-terminal motif [PF03271.19, score=48.5]; Calponin homology (CH) domain [PF00307.33, score=45.4]} {Human: ENSG00000101367, MAPRE1, microtubule associated protein RP/EB family member 1, [RH, Score=256, Expect=1e-84]; ENSG00000084764, MAPRE3, microtubule associated protein RP/EB family member 3, [RH, Score=247, Expect=5e-81]} {Mouse: ENSMUSG00000027479, Mapre1, microtubule-associated protein, RP/EB family, member 1, [RH, Score=255, Expect=2e-84]; ENSMUSG00000029166, Mapre3, microtubule-associated protein, RP/EB family, member 3, [RH, Score=244, Expect=5e-80]} {Dmel: FBgn0027066, Eb1, [RH, Score=258, Expect=1e-85]} {Celegans: WBGene00013344, ebp-1, Microtubule End Binding Protein, [RH, Score=218, Expect=2e-69]} {Smed: dd_Smed_v6_1322_0_2, dd_Smed_v6_1322_0_2, [RH, Score=309, Expect=3e-105]} {RNA1509_15908} {RNA1310_22066} {RNA815_24384}

Mlig455_005273 {REF} {Length: 1471} {TRANSSPLICED} {Pfam: EB1-like C-terminal motif [PF03271.19, score=48.5]; Calponin homology (CH) domain [PF00307.33, score=45.4]} {Human: ENSG00000101367, MAPRE1, microtubule associated protein RP/EB family member 1, [RH, Score=256, Expect=1e-84]; ENSG00000084764, MAPRE3, microtubule associated protein RP/EB family member 3, [RH, Score=247, Expect=5e-81]} {Mouse: ENSMUSG00000027479, Mapre1, microtubule-associated protein, RP/EB family, member 1, [RH, Score=255, Expect=2e-84]; ENSMUSG00000029166, Mapre3, microtubule-associated protein, RP/EB family, member 3, [RH, Score=244, Expect=5e-80]} {Dmel: FBgn0027066, Eb1, [RH, Score=258, Expect=1e-85]} {Celegans: WBGene00013344, ebp-1, Microtubule End Binding Protein, [RH, Score=218, Expect=2e-69]} {Smed: dd_Smed_v6_1322_0_2, dd_Smed_v6_1322_0_2, [RH, Score=309, Expect=3e-105]} {RNA1509_15908} {RNA1310_22066} {RNA815_24384}
36. MligTC455_03502 319 6.65 Mlig455_042614

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.455

1.753 - - - 0.988 0.765 - Mlig455_042614 {REF} {Length: 2362} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=36.5]} {Smed: dd_Smed_v6_8117_0_1, dd_Smed_v6_8117_0_1, [Score=75.5, Expect=1e-14]} {RNA1509_23110, RNA1509_53674} {RNA1310_10802.1, RNA1509_23110, RNA1509_53674} {RNA1509_23110, RNA1509_53674, RNA815_4389.1}
37. MligTC455_29431 797 16.59 Mlig455_025887

Neo: -

Age: -

Region-enriched R5: 1.079/0.00034

RPS6KB1 1.752 - - - 0.958 0.794 - Mlig455_025887 {REF} {Length: 4756} {Pfam: Protein kinase domain [PF00069.27, score=231.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.8]; Integrase zinc binding domain [PF17921.3, score=47.6]; Protein kinase C terminal domain [PF00433.26, score=40.8]; Kinase-like [PF14531.8, score=27.5]; ABC1 atypical kinase-like domain [PF03109.18, score=18.1]} {Human: ENSG00000108443, RPS6KB1, ribosomal protein S6 kinase B1, [RH, Score=489, Expect=6e-168]} {Mouse: ENSMUSG00000020516, Rps6kb1, ribosomal protein S6 kinase, polypeptide 1, [RH, Score=489, Expect=3e-167]} {Dmel: FBgn0283472, S6k, Ribosomal protein S6 kinase, [RH, Score=467, Expect=4e-159]} {Celegans: WBGene00012929, rsks-1, Ribosomal protein S6 kinase beta, [RH, Score=457, Expect=1e-154]} {Smed: dd_Smed_v6_5658_0_1, dd_Smed_v6_5658_0_1, [RH, Score=466, Expect=3e-159]} {RNA1509_12463} {RNA1310_6456} {RNA815_17601}
38. MligTC455_45964 474 9.88 Mlig455_046888

Neo: -

Age: -

Region-enriched R2: 1.528/0.03625

CYB5R4 1.751 - - - 0.964 0.787 - Mlig455_046888 {REF} {Length: 2950} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=32.2} {Pfam: Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=85.8]; Oxidoreductase NAD-binding domain [PF00175.23, score=54.7]; Oxidoreductase FAD-binding domain [PF00970.26, score=38.6]} {Human: ENSG00000065615, CYB5R4, cytochrome b5 reductase 4, [RH, Score=140, Expect=1e-35]} {Mouse: ENSMUSG00000032872, Cyb5r4, cytochrome b5 reductase 4, [RH, Score=142, Expect=4e-36]} {Dmel: FBgn0034442, CG11257, [RH, Score=147, Expect=4e-38]} {Celegans: WBGene00013123, Y52B11A.3, [RH, Score=169, Expect=4e-46]} {Smed: dd_Smed_v6_8629_0_1, dd_Smed_v6_8629_0_1, [RH, Score=146, Expect=5e-38]} {RNA1509_18530} {RNA1310_12400, RNA1509_18530} {RNA1509_18530, RNA815_28929}
39. MligTC455_43451 2312 48.16 Mlig455_006679, Mlig455_006729

Neo: -

Age: Down-Up-Down

1.75 - - - 0.967 0.783 -

Mlig455_006679 {REF} {Length: 1801} {RNA1509_30562, RNA1509_31928} {RNA1310_18324, RNA1509_30562, RNA1509_31928} {RNA1509_30562, RNA1509_31928, RNA815_16556}

Mlig455_006729 {REF} {Length: 1812} {RNA1509_30562, RNA1509_41495} {RNA1310_18324, RNA1509_41495} {RNA1509_41495, RNA815_16556}
40. MligTC455_53152 292 6.09 Mlig455_008262, Mlig455_040622

Neo: Int S/G2/M

Age: -

Regeneration-upregulated R2: 4.997

Regeneration-enriched R2: 4.997

TRIP13 1.746 - - - 0.972 0.774 -

Mlig455_008262 {REF} {Length: 2335} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=100.2]; AAA domain [PF13401.8, score=35.0]; AAA ATPase domain [PF13191.8, score=27.4]; AAA domain [PF13238.8, score=27.1]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=23.2]} {Human: ENSG00000071539, TRIP13, thyroid hormone receptor interactor 13, [RH, Score=314, Expect=9e-102]} {Mouse: ENSMUSG00000021569, Trip13, thyroid hormone receptor interactor 13, [RH, Score=319, Expect=6e-104]} {Dmel: FBgn0051453, pch2, pachytene checkpoint 2, [RH, Score=259, Expect=4e-81]} {Celegans: WBGene00008641, pch-2, Putative pachytene checkpoint protein 2, [RH, Score=241, Expect=3e-74]} {Smed: dd_Smed_v6_46627_0_1, dd_Smed_v6_46627_0_1, [RH, Score=257, Expect=6e-83]} {RNA1509_17149} {RNA1310_22314} {RNA815_11155}

Mlig455_040622 {REF} {Length: 2141} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=100.4]; AAA domain [PF13401.8, score=35.2]; AAA ATPase domain [PF13191.8, score=27.5]; AAA domain [PF13238.8, score=27.4]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=23.4]} {Human: ENSG00000071539, TRIP13, thyroid hormone receptor interactor 13, [RH, Score=316, Expect=6e-103]} {Mouse: ENSMUSG00000021569, Trip13, thyroid hormone receptor interactor 13, [RH, Score=320, Expect=7e-105]} {Dmel: FBgn0051453, pch2, pachytene checkpoint 2, [RH, Score=259, Expect=1e-81]} {Celegans: WBGene00008641, pch-2, Putative pachytene checkpoint protein 2, [RH, Score=242, Expect=4e-75]} {Smed: dd_Smed_v6_46627_0_1, dd_Smed_v6_46627_0_1, [RH, Score=259, Expect=3e-84]} {RNA1509_17149} {RNA1310_22314, RNA1509_17149} {RNA1509_17149, RNA815_11155}
41. MligTC455_53612 1108 23.09 Mlig455_023847, Mlig455_046530, Mlig455_046638, Mlig455_046657

Neo: -

Age: Down-Up-Up

Region-enriched R2: 1.470/0.03843

1.746 0.955 - - - - 0.791

Mlig455_023847 {REF} {Length: 2954} {TRANSSPLICED} {RNA1509_48720, RNA1509_59611} {RNA1310_8026, RNA1509_48720, RNA1509_59611} {RNA1509_48720, RNA1509_59611, RNA815_3300.1}

Mlig455_046530 {REF} {Length: 2423} {RNA1509_56940} {RNA1310_8026} {RNA815_3300.1}

Mlig455_046638 {REF} {Length: 2807} {RNA1509_56940} {RNA1310_8026} {RNA815_3300.1}

Mlig455_046657 {REF} {Length: 2718} {RNA1509_56940} {RNA1310_8026, RNA1509_56940} {RNA1509_56940, RNA815_3300.1}
42. MligTC455_32722 559 11.65 Mlig455_032808

Neo: -

Age: -

CEP78 1.743 - - - 0.985 - 0.758 Mlig455_032808 {REF} {Length: 3328} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=38.0]} {Human: ENSG00000148019, CEP78, centrosomal protein 78, [RH, Score=364, Expect=2e-113]} {Mouse: ENSMUSG00000041491, Cep78, centrosomal protein 78, [RH, Score=365, Expect=3e-113]} {Dmel: FBgn0038248, CG7886, [RH, Score=166, Expect=4e-42]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=70.9, Expect=3e-12]} {Smed: dd_Smed_v6_9671_0_1, dd_Smed_v6_9671_0_1, [RH, Score=486, Expect=5e-159]} {RNA1509_57546, RNA1509_8002} {RNA1310_3841, RNA1509_57546, RNA1509_8002} {RNA1509_57546, RNA1509_8002, RNA815_4356}
43. MligTC455_47803 609 12.69 Mlig455_042586

Neo: -

Age: -

Region-enriched R2: 2.248/0.00320

SMKR1 1.741 - - - 0.988 0.753 - Mlig455_042586 {REF} {Length: 1831} {TRANSSPLICED} {Human: ENSG00000240204, SMKR1, small lysine rich protein 1, [RH, Score=54.3, Expect=5e-11]} {Dmel: FBgn0266615, CG45122, [Score=41.6, Expect=5e-06]} {Smed: dd_Smed_v6_10158_0_1, dd_Smed_v6_10158_0_1, [RH, Score=44.3, Expect=3e-07]} {RNA1509_37781} {RNA1310_41265, RNA1509_37781} {RNA1509_37781, RNA815_11227.2}
44. MligTC455_27650 178 3.72 Mlig455_017720

Neo: -

Age: logFC(26M/2M)=-0.928

Region-enriched R2: 3.586/0.00082

ADAM33 1.735 0.968 - - - 0.767 - Mlig455_017720 {REF} {Length: 4499} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=124.3]; Disintegrin [PF00200.25, score=66.8]; Metallo-peptidase family M12 [PF13688.8, score=62.2]; ADAM cysteine-rich [PF08516.14, score=61.3]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=33.1]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=237, Expect=1e-64]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [Score=233, Expect=2e-63]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=230, Expect=2e-62]; ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=228, Expect=4e-61]; ENSG00000069206, ADAM7, ADAM metallopeptidase domain 7, [Score=226, Expect=4e-61]; ENSG00000042980, ADAM28, ADAM metallopeptidase domain 28, [Score=226, Expect=4e-61]} {Mouse: ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [RH, Score=248, Expect=4e-69]; ENSMUSG00000050190, Gm5346, predicted gene 5346, [RH, Score=239, Expect=3e-66]} {Dmel: FBgn0265140, Meltrin, [RH, Score=288, Expect=1e-79]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=246, Expect=3e-67]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=225, Expect=3e-60]} {RNA1509_7654} {RNA1310_9319.1} {RNA815_4173.1}
45. MligTC455_53777 1160 24.18 Mlig455_023453

Neo: -

Age: -

Region-enriched R2: 1.441/0.02700

1.731 - 0.767 - 0.964 - - Mlig455_023453 {REF} {Length: 3263} {TRANSSPLICED} {Pfam: 6-bladed beta-propeller [PF17170.6, score=31.5]; zinc-RING finger domain [PF14634.8, score=25.9]; NHL repeat [PF01436.23, score=24.9]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=24.6]; RING-type zinc-finger [PF13445.8, score=23.6]; Prokaryotic RING finger family 4 [PF14447.8, score=19.6]} {Mouse: ENSMUSG00000031651, Triml1, tripartite motif family-like 1, [Score=49.7, Expect=9e-06]} {RNA1509_17795, RNA1509_5029} {RNA1310_5086.1, RNA1509_17795, RNA1509_5029} {RNA1509_17795, RNA1509_5029, RNA815_4935.1}
46. MligTC455_33700 888 18.5 Mlig455_007054

Neo: -

Age: logFC(26M/2M)=0.242

SACS 1.73 - - - 0.959 - 0.771 Mlig455_007054 {REF} {Length: 10881} {TRANSSPLICED} {Pfam: HEPN domain [PF05168.16, score=40.4]} {Human: ENSG00000151835, SACS, sacsin molecular chaperone, [Score=656, Expect=0.0]} {Mouse: ENSMUSG00000048279, Sacs, sacsin, [RH, Score=648, Expect=0.0]} {RNA1509_13851, RNA1509_2130, RNA1509_30347, RNA1509_42675} {RNA1310_137.1, RNA1509_13851, RNA1509_30347, RNA1509_42675} {RNA1509_13851, RNA1509_30347, RNA1509_42675, RNA815_91}
47. MligTC455_23285 227 4.72 Mlig455_012945

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.196

DUS1L 1.728 - - - 0.988 - 0.740 Mlig455_012945 {REF} {Length: 4404} {TRANSSPLICED} {Pfam: Dihydrouridine synthase (Dus) [PF01207.19, score=223.8]; NHL repeat [PF01436.23, score=30.5]} {Human: ENSG00000169718, DUS1L, dihydrouridine synthase 1 like, [Score=226, Expect=7e-65]} {Mouse: ENSMUSG00000025155, Dus1l, dihydrouridine synthase 1-like (S. cerevisiae), [Score=229, Expect=5e-66]} {Dmel: FBgn0031238, CG3645, [Score=220, Expect=1e-62]} {Celegans: WBGene00009452, F36A2.2, [Score=178, Expect=1e-47]} {Smed: dd_Smed_v6_5584_0_1, dd_Smed_v6_5584_0_1, [Score=234, Expect=6e-68]} {RNA1509_23284} {RNA1310_18372} {RNA815_3872}
48. MligTC455_51996 283 5.91 Mlig455_039586, Mlig455_052628

Neo: -

Age: -

1.724 - - - 0.967 - 0.757

Mlig455_039586 {REF} {Length: 2209} {RNA1509_1200} {RNA1310_38305.1} {RNA815_14771.1}

Mlig455_052628 {REF} {Length: 1606} {RNA1509_1693} {RNA1310_38305.1} {RNA815_14771.1}
49. MligTC455_26365 154 3.21 Mlig455_013552

Neo: -

Age: logFC(26M/2M)=-0.510

Region-enriched R4: 3.332/0.01426

MAP3K15 1.721 - 0.729 - 0.992 - - Mlig455_013552 {REF} {Length: 2480} {Pfam: Protein kinase domain [PF00069.27, score=137.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=96.5]; Fungal protein kinase [PF17667.3, score=25.9]; Phosphotransferase enzyme family [PF01636.25, score=21.0]} {Human: ENSG00000180815, MAP3K15, mitogen-activated protein kinase kinase kinase 15, [Score=122, Expect=3e-30]; ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=117, Expect=4e-29]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=117, Expect=6e-29]; ENSMUSG00000026277, Stk25, serine/threonine kinase 25 (yeast), [Score=112, Expect=1e-27]; ENSMUSG00000031112, Stk26, serine/threonine kinase 26, [Score=112, Expect=4e-28]; ENSMUSG00000020272, Stk10, serine/threonine kinase 10, [Score=112, Expect=3e-27]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=118, Expect=3e-29]} {Celegans: WBGene00003144, max-2, Serine/threonine-protein kinase max-2, [Score=102, Expect=2e-25]} {Smed: dd_Smed_v6_2030_0_14, dd_Smed_v6_2030_0_14, [Score=117, Expect=7e-30]} {RNA1509_48626} {RNA1310_22200.1} {RNA815_5323.2}
50. MligTC455_19363 562 11.7 Mlig455_029807

Neo: -

Age: -

CEP112 1.719 - - 0.741 0.978 - - Mlig455_029807 {REF} {Length: 3144} {Pfam: Domain of unknown function (DUF4485) [PF14846.8, score=67.7]} {Human: ENSG00000154240, CEP112, centrosomal protein 112, [RH, Score=195, Expect=4e-51]} {Mouse: ENSMUSG00000020728, Cep112, centrosomal protein 112, [RH, Score=192, Expect=2e-50]} {RNA1509_15407} {RNA1310_5084} {RNA815_34619}
51. MligTC455_35663 475 9.89 Mlig455_028426

Neo: -

Age: -

CLHC1 1.715 - - - 0.964 - 0.751 Mlig455_028426 {REF} {Length: 1005} {Pfam: Translin-associated factor X-interacting N-terminus [PF15739.7, score=57.3]; Clathrin-H-link [PF13838.8, score=34.4]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [RH, Score=155, Expect=8e-40]} {Mouse: ENSMUSG00000020461, Clhc1, clathrin heavy chain linker domain containing 1, [RH, Score=160, Expect=8e-42]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=51.2, Expect=2e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [RH, Score=145, Expect=4e-37]} {RNA1509_25530} {RNA1310_5794.1} {RNA815_1706}
52. MligTC455_40939 213 4.43 Mlig455_002892

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.627

1.714 - - - 0.992 0.722 - Mlig455_002892 {REF} {Length: 2872} {Smed: dd_Smed_v6_13623_0_1, dd_Smed_v6_13623_0_1, [Score=57.4, Expect=8e-09]} {RNA1509_30289} {RNA1310_5962} {RNA815_9809}
53. MligTC455_50895 674 14.05 Mlig455_008440, Mlig455_018231

Neo: Irradiation

Age: Up-Down-Down

1.712 - - 0.722 0.990 - -

Mlig455_008440 {REF} {Length: 3695} {TRANSSPLICED} {RNA1509_32831, RNA1509_53550, RNA1509_59445} {RNA1310_40800, RNA1509_32831, RNA1509_53550, RNA1509_59445} {RNA1509_32831, RNA1509_53550, RNA1509_59445, RNA815_25255}

Mlig455_018231 {REF} {Length: 4261} {TRANSSPLICED} {RNA1509_32831} {RNA1310_40800} {RNA815_25255}
54. MligTC455_53033 178 3.71 Mlig455_005972

Neo: -

Age: -

1.712 - - - 0.993 0.719 - Mlig455_005972 {REF} {Length: 703} {NoTransDecoderORF} {RNA1310_47894} {RNA815_53305}
55. MligTC455_43400 2448 51 Mlig455_042374, Mlig455_043600

Neo: -

Age: logFC(26M/2M)=-0.280

PRKAR2A 1.711 - - - 0.973 0.738 -

Mlig455_042374 {REF} {Length: 3412} {TRANSSPLICED} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=134.7]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=55.4]} {Human: ENSG00000114302, PRKAR2A, protein kinase cAMP-dependent type II regulatory subunit alpha, [Score=311, Expect=2e-102]} {Mouse: ENSMUSG00000032601, Prkar2a, protein kinase, cAMP dependent regulatory, type II alpha, [Score=314, Expect=7e-104]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [Score=318, Expect=1e-105]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=227, Expect=6e-71]} {Smed: dd_Smed_v6_4188_0_1, dd_Smed_v6_4188_0_1, [Score=337, Expect=2e-113]} {RNA1509_34018, RNA1509_3885} {RNA1310_3950, RNA1509_34018} {RNA1509_34018, RNA815_7205}

Mlig455_043600 {REF} {Length: 3380} {TRANSSPLICED} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=134.8]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=55.4]} {Human: ENSG00000114302, PRKAR2A, protein kinase cAMP-dependent type II regulatory subunit alpha, [Score=311, Expect=1e-102]} {Mouse: ENSMUSG00000032601, Prkar2a, protein kinase, cAMP dependent regulatory, type II alpha, [Score=314, Expect=8e-104]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [Score=318, Expect=1e-105]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=227, Expect=6e-71]} {Smed: dd_Smed_v6_4188_0_1, dd_Smed_v6_4188_0_1, [Score=337, Expect=2e-113]} {RNA1509_3885, RNA1509_47776, RNA1509_52007} {RNA1310_3950, RNA1509_3885, RNA1509_47776, RNA1509_52007} {RNA1509_3885, RNA1509_47776, RNA1509_52007, RNA815_7205}
56. MligTC455_51425 7476 155.75 Mlig455_022033

Neo: -

Age: Down-Up-Down

CALM2 1.711 - - - 0.960 0.751 - Mlig455_022033 {REF} {Length: 2160} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=141.5]; EF-hand domain pair [PF13499.8, score=125.9]; EF-hand domain pair [PF13833.8, score=108.2]; EF-hand domain [PF13405.8, score=98.7]; EF hand [PF13202.8, score=95.3]; EF-hand domain [PF14658.8, score=61.9]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=40.9]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=32.1]; EF-hand domain [PF08976.13, score=28.8]; Uncharacterised protein family (UPF0154) [PF03672.15, score=23.7]; Ca2+ insensitive EF hand [PF08726.12, score=21.4]; Dockerin type I domain [PF00404.20, score=21.1]; Caleosin related protein [PF05042.15, score=18.8]; Repeat of unknown function (DUF1103) [PF06513.13, score=18.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [RH, Score=295, Expect=2e-103]; ENSG00000198668, CALM1, calmodulin 1, [RH, Score=293, Expect=2e-103]; ENSG00000160014, CALM3, calmodulin 3, [RH, Score=291, Expect=2e-102]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [RH, Score=291, Expect=1e-102]; ENSMUSG00000036438, Calm2, calmodulin 2, [RH, Score=291, Expect=1e-102]; ENSMUSG00000001175, Calm1, calmodulin 1, [RH, Score=291, Expect=1e-102]} {Dmel: FBgn0000253, Cam, Calmodulin, [RH, Score=294, Expect=4e-104]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [RH, Score=295, Expect=1e-104]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [RH, Score=295, Expect=8e-105]} {RNA1509_10228, RNA1509_17166, RNA1509_22818, RNA1509_34197} {RNA1310_22130, RNA1509_17166, RNA1509_22818, RNA1509_34197} {RNA1509_17166, RNA1509_22818, RNA1509_34197, RNA815_4214.1}
57. MligTC455_50355 38 0.79 Mlig455_057631

Neo: -

Age: -

Region-enriched R2: 7.639/0.01837

1.71 0.965 - - - 0.745 - Mlig455_057631 {REF} {Length: 1003} {Pfam: WSC domain [PF01822.21, score=45.2]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=6e-06]} {RNA1310_44307} {RNA815_33128}
58. MligTC455_47413 396 8.26 Mlig455_038928

Neo: -

Age: logFC(26M/2M)=-0.855

1.709 - - - 0.995 0.714 - Mlig455_038928 {REF} {Length: 2815} {RNA1509_11672, RNA1509_49419, RNA1509_9488} {RNA1310_3197, RNA1509_11672, RNA1509_49419, RNA1509_9488} {RNA1509_11672, RNA1509_49419, RNA1509_9488, RNA815_9217}
59. MligTC455_47332 284 5.91 Mlig455_025909

Neo: -

Age: logFC(26M/2M)=-0.384

1.708 - - - 0.991 - 0.717 Mlig455_025909 {REF} {Length: 2782} {Pfam: Dynamin family [PF00350.25, score=36.8]} {Smed: dd_Smed_v6_1371_0_1, dd_Smed_v6_1371_0_1, [Score=115, Expect=2e-27]} {RNA1509_5996} {RNA1310_3463.1} {RNA815_1104.1}
60. MligTC455_28992 248 5.17 Mlig455_007574

Neo: -

Age: -

Region-enriched R3: 5.359/0.00013

SIX1 1.707 - - 0.718 0.989 - - Mlig455_007574 {REF} {Length: 2756} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=146.3]; Homeodomain [PF00046.31, score=56.2]; Homeobox KN domain [PF05920.13, score=49.9]} {Human: ENSG00000126778, SIX1, SIX homeobox 1, [Score=313, Expect=9e-104]; ENSG00000170577, SIX2, SIX homeobox 2, [Score=307, Expect=3e-101]} {Mouse: ENSMUSG00000051367, Six1, sine oculis-related homeobox 1, [Score=313, Expect=5e-104]; ENSMUSG00000024134, Six2, sine oculis-related homeobox 2, [Score=308, Expect=1e-101]} {Dmel: FBgn0003460, so, sine oculis, [Score=303, Expect=3e-98]} {Celegans: WBGene00000454, ceh-33, Homeobox protein ceh-33, [RH, Score=246, Expect=2e-78]} {Smed: dd_Smed_v6_15436_0_1, dd_Smed_v6_15436_0_1, [RH, Score=326, Expect=2e-106]} {RNA1509_55511} {RNA1310_27700, RNA1509_55511} {RNA1509_55511, RNA815_16067}
61. MligTC455_13930 199 4.15 Mlig455_041651

Neo: -

Age: -

1.705 - - 0.718 0.987 - - Mlig455_041651 {REF} {Length: 173} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_58650} {RNA1310_35597} {RNA815_15920.2}
62. MligTC455_31161 617 12.85 Mlig455_022730

Neo: -

Age: Up-Down-Down

MLXIPL 1.705 - - - 0.968 - 0.737 Mlig455_022730 {REF} {Length: 7247} {TRANSSPLICED} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=38.2]} {Human: ENSG00000009950, MLXIPL, MLX interacting protein like, [RH, Score=163, Expect=1e-40]} {Mouse: ENSMUSG00000005373, Mlxipl, MLX interacting protein-like, [RH, Score=165, Expect=2e-41]} {Dmel: FBgn0032940, Mondo, [RH, Score=145, Expect=4e-35]} {Celegans: WBGene00003378, mml-1, Protein WBSCR14 homolog, [RH, Score=135, Expect=3e-32]} {Smed: dd_Smed_v6_9226_0_1, dd_Smed_v6_9226_0_1, [RH, Score=144, Expect=3e-35]} {RNA1509_10185, RNA1509_53815, RNA1509_60070} {RNA1310_3768, RNA1509_10185, RNA1509_53815, RNA1509_60070} {RNA1509_10185, RNA1509_53815, RNA1509_60070, RNA815_3226}
63. MligTC455_43573 297 6.19 Mlig455_037946

Neo: -

Age: Down-Up-Down

1.701 0.725 - - 0.976 - - Mlig455_037946 {REF} {Length: 3077} {Pfam: Protein-arginine deiminase (PAD) N-terminal domain [PF08526.12, score=27.2]} {RNA1509_47003} {RNA1310_35286, RNA1509_47003} {RNA1509_47003, RNA815_20576}
64. MligTC455_45781 345 7.19 Mlig455_035300

Neo: -

Age: logFC(26M/2M)=0.368

1.698 - - - 0.979 0.719 - Mlig455_035300 {REF} {Length: 3621} {RNA1509_51038} {RNA1310_7872.1} {RNA815_15245}
65. MligTC455_23106 623 12.99 Mlig455_001508

Neo: -

Age: -

1.697 - - - 0.963 - 0.734 Mlig455_001508 {REF} {Length: 3312} {Pfam: TNF(Tumour Necrosis Factor) family [PF00229.20, score=18.8]} {RNA1509_18455, RNA1509_39449, RNA1509_44669, RNA1509_56190} {RNA1310_19889, RNA1509_18455, RNA1509_39449, RNA1509_44669, RNA1509_56190} {RNA1509_18455, RNA1509_39449, RNA1509_44669, RNA1509_56190, RNA815_6035.1}
66. MligTC455_35422 838 17.46 Mlig455_043711

Neo: -

Age: Down-Down-Up

COG2 1.697 - 0.707 - 0.990 - - Mlig455_043711 {REF} {Length: 7789} {TRANSSPLICED} {Pfam: COG (conserved oligomeric Golgi) complex component, COG2 [PF06148.13, score=104.7]; Domain of unknown function (DUF3510) [PF12022.10, score=95.0]; TRAF-type zinc finger [PF02176.20, score=30.2]} {Human: ENSG00000135775, COG2, component of oligomeric golgi complex 2, [Score=284, Expect=3e-81]} {Mouse: ENSMUSG00000031979, Cog2, component of oligomeric golgi complex 2, [Score=283, Expect=6e-81]} {Dmel: FBgn0026634, ldlCp, ldlCp-related protein, [Score=202, Expect=8e-54]} {Celegans: WBGene00000585, cogc-2, Conserved oligomeric Golgi complex subunit 2, [Score=134, Expect=6e-32]} {Smed: dd_Smed_v6_5210_0_1, dd_Smed_v6_5210_0_1, [Score=284, Expect=1e-81]} {RNA1509_12449, RNA1509_21794} {RNA1310_5891, RNA1509_21794} {RNA1509_21794, RNA815_1472}
67. MligTC455_07773 773 16.11 Mlig455_031541

Neo: -

Age: -

1.694 - - 0.736 0.958 - - Mlig455_031541 {REF} {Length: 1316} {NoTransDecoderORF} {RNA1509_50184} {RNA1310_22266} {RNA815_9720}
68. MligTC455_40852 128 2.66 Mlig455_042301

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.671

Region-enriched R2: 6.158/0.00357

PKDREJ 1.694 0.962 - - - 0.732 - Mlig455_042301 {REF} {Length: 11184} {Pfam: Polycystin cation channel [PF08016.14, score=273.5]; PKD domain [PF00801.22, score=86.2]; PLAT/LH2 domain [PF01477.25, score=67.1]; REJ domain [PF02010.17, score=66.8]; PKD domain [PF18911.2, score=62.3]; Ion transport protein [PF00520.33, score=45.4]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=283, Expect=2e-75]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=273, Expect=2e-72]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=158, Expect=3e-38]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=254, Expect=4e-67]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=514, Expect=2e-146]} {RNA1509_8046} {RNA1310_93, RNA1509_8046} {RNA1509_8046, RNA815_1216}
69. MligTC455_12269 42 0.88 Mlig455_062448

Neo: -

Age: -

Region-enriched R2: 6.351/0.02912

1.692 0.951 0.741 - - - - Mlig455_062448 {REF} {Length: 941} {RNA1310_43338} {RNA815_24238}
70. MligTC455_18870 1001 20.86 Mlig455_002445, Mlig455_002730

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.707

Region-enriched R2: 2.415/0.00019

DNAH7 1.691 0.704 - - 0.987 - -

Mlig455_002445 {REF} {Length: 13764} {TRANSSPLICED} {Pfam: Dynein heavy chain C-terminal domain [PF18199.3, score=397.0]; P-loop containing dynein motor region D4 [PF12780.9, score=362.4]; ATP-binding dynein motor region [PF12781.9, score=318.6]; P-loop containing dynein motor region [PF12775.9, score=280.4]; Dynein heavy chain AAA lid domain [PF18198.3, score=203.4]; Microtubule-binding stalk of dynein motor [PF12777.9, score=185.3]; Dynein heavy chain AAA lid domain [PF17852.3, score=117.6]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=102.5]; AAA+ lid domain [PF17857.3, score=77.9]; AAA domain (dynein-related subfamily) [PF07728.16, score=51.0]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=20.5]; AAA domain [PF13401.8, score=19.5]} {Human: ENSG00000118997, DNAH7, dynein axonemal heavy chain 7, [Score=3468, Expect=0.0]} {Mouse: ENSMUSG00000101337, Dnah7c, dynein, axonemal, heavy chain 7C, [Score=3486, Expect=0.0]; ENSMUSG00000041144, Dnah7b, dynein, axonemal, heavy chain 7B, [Score=3474, Expect=0.0]; ENSMUSG00000096141, Dnah7a, dynein, axonemal, heavy chain 7A, [Score=3472, Expect=0.0]} {Dmel: FBgn0013810, Dhc36C, Dynein heavy chain at 36C, [Score=2909, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=700, Expect=0.0]} {Smed: dd_Smed_v6_5350_0_1, dd_Smed_v6_5350_0_1, [Score=3768, Expect=0.0]} {RNA1509_228} {RNA1310_71} {RNA815_248}

Mlig455_002730 {REF} {Length: 420} {Pfam: Dynein heavy chain, N-terminal region 2 [PF08393.15, score=27.2]} {Human: ENSG00000118997, DNAH7, dynein axonemal heavy chain 7, [Score=98.2, Expect=1e-24]} {Mouse: ENSMUSG00000096141, Dnah7a, dynein, axonemal, heavy chain 7A, [Score=100, Expect=2e-25]; ENSMUSG00000041144, Dnah7b, dynein, axonemal, heavy chain 7B, [Score=98.6, Expect=8e-25]; ENSMUSG00000101337, Dnah7c, dynein, axonemal, heavy chain 7C, [Score=97.8, Expect=2e-24]} {Smed: dd_Smed_v6_13792_0_2, dd_Smed_v6_13792_0_2, [Score=102, Expect=2e-26]} {RNA1509_228} {RNA1310_71} {RNA815_34.1}
71. MligTC455_18871 1004 20.91 Mlig455_002731, Mlig455_063346

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=-1.287

Region-enriched R2: 2.201/0.00053

DNAH7 1.691 - - - 0.986 0.705 -

Mlig455_002731 {REF} {Length: 838} {TRANSSPLICED} {Human: ENSG00000118997, DNAH7, dynein axonemal heavy chain 7, [Score=144, Expect=1e-39]} {Mouse: ENSMUSG00000041144, Dnah7b, dynein, axonemal, heavy chain 7B, [Score=142, Expect=4e-38]; ENSMUSG00000096141, Dnah7a, dynein, axonemal, heavy chain 7A, [Score=137, Expect=2e-36]; ENSMUSG00000101337, Dnah7c, dynein, axonemal, heavy chain 7C, [Score=135, Expect=6e-36]} {Dmel: FBgn0013810, Dhc36C, Dynein heavy chain at 36C, [Score=78.2, Expect=3e-16]} {Smed: dd_Smed_v6_13792_0_1, dd_Smed_v6_13792_0_1, [Score=236, Expect=2e-71]} {RNA1509_228} {RNA1310_71} {RNA815_34.1}

Mlig455_063346 {REF} {Length: 12883} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=514.7]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=491.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=396.1]; P-loop containing dynein motor region D4 [PF12780.9, score=361.9]; ATP-binding dynein motor region [PF12781.9, score=323.9]; P-loop containing dynein motor region [PF12775.9, score=283.4]; Dynein heavy chain AAA lid domain [PF18198.3, score=202.8]; Microtubule-binding stalk of dynein motor [PF12777.9, score=186.0]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=158.5]; Dynein heavy chain AAA lid domain [PF17852.3, score=117.3]; AAA+ lid domain [PF17857.3, score=76.6]; AAA domain (dynein-related subfamily) [PF07728.16, score=72.3]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=32.8]; AAA ATPase domain [PF13191.8, score=24.9]; AAA domain [PF13401.8, score=23.3]} {Human: ENSG00000118997, DNAH7, dynein axonemal heavy chain 7, [RH, Score=5532, Expect=0.0]} {Mouse: ENSMUSG00000101337, Dnah7c, dynein, axonemal, heavy chain 7C, [RH, Score=5525, Expect=0.0]; ENSMUSG00000041144, Dnah7b, dynein, axonemal, heavy chain 7B, [RH, Score=5516, Expect=0.0]; ENSMUSG00000096141, Dnah7a, dynein, axonemal, heavy chain 7A, [RH, Score=5500, Expect=0.0]} {Dmel: FBgn0013810, Dhc36C, Dynein heavy chain at 36C, [RH, Score=4478, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=728, Expect=0.0]} {Smed: dd_Smed_v6_5350_0_1, dd_Smed_v6_5350_0_1, [RH, Score=4420, Expect=0.0]} {RNA1509_11080, RNA1509_21150, RNA1509_21155, RNA1509_228, RNA1509_28894} {RNA1310_71, RNA1509_11080, RNA1509_21150, RNA1509_21155, RNA1509_228, RNA1509_28894} {RNA1509_11080, RNA1509_21150, RNA1509_21155, RNA1509_228, RNA1509_28894, RNA815_248}
72. MligTC455_44209 764 15.92 Mlig455_011059

Neo: -

Age: -

EGR1 1.691 - 0.731 - 0.960 - - Mlig455_011059 {REF} {Length: 2031} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=54.2]; Zinc-finger double domain [PF13465.8, score=48.5]; C2H2-type zinc finger [PF13894.8, score=44.8]; C2H2-type zinc finger [PF13912.8, score=32.9]} {Human: ENSG00000120738, EGR1, early growth response 1, [RH, Score=159, Expect=1e-43]; ENSG00000179388, EGR3, early growth response 3, [RH, Score=155, Expect=2e-43]; ENSG00000122877, EGR2, early growth response 2, [RH, Score=154, Expect=6e-42]} {Mouse: ENSMUSG00000038418, Egr1, early growth response 1, [RH, Score=159, Expect=9e-44]; ENSMUSG00000033730, Egr3, early growth response 3, [RH, Score=155, Expect=2e-43]; ENSMUSG00000116458, Egr2, early growth response 2, [RH, Score=154, Expect=3e-42]; ENSMUSG00000037868, Egr2, early growth response 2, [RH, Score=154, Expect=3e-42]} {Dmel: FBgn0003499, sr, stripe, [RH, Score=163, Expect=5e-44]} {Celegans: WBGene00007772, egrh-1, EGR (Early Growth factor Response factor) Homolog, [RH, Score=153, Expect=3e-42]} {Smed: dd_Smed_v6_7091_0_1, dd_Smed_v6_7091_0_1, [RH, Score=136, Expect=1e-36]} {RNA1509_16885, RNA1509_28595} {RNA1310_14689, RNA1509_16885, RNA1509_28595} {RNA1509_16885, RNA1509_28595, RNA815_10071.1}
73. MligTC455_12314 120 2.5 Mlig455_010420

Neo: -

Age: -

HDC 1.688 - - - 0.986 0.702 - Mlig455_010420 {REF} {Length: 2937} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=449.3]} {Human: ENSG00000140287, HDC, histidine decarboxylase, [RH, Score=517, Expect=5e-176]} {Mouse: ENSMUSG00000027360, Hdc, histidine decarboxylase, [RH, Score=506, Expect=1e-171]} {Dmel: FBgn0050446, Tdc2, Tyrosine decarboxylase 2, [RH, Score=582, Expect=0.0]} {Celegans: WBGene00006562, tdc-1, Tyrosine decarboxylase, [RH, Score=545, Expect=0.0]} {Smed: dd_Smed_v6_11320_0_1, dd_Smed_v6_11320_0_1, [Score=470, Expect=3e-160]} {RNA1310_34123} {RNA815_44610}
74. MligTC455_35894 23 0.48 Mlig455_029906

Neo: -

Age: -

RYK 1.687 0.958 - - - 0.729 - Mlig455_029906 {REF} {Length: 3571} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=210.1]; WIF domain [PF02019.20, score=110.2]; Protein kinase domain [PF00069.27, score=79.8]} {Human: ENSG00000163785, RYK, receptor-like tyrosine kinase, [Score=202, Expect=7e-57]} {Mouse: ENSMUSG00000032547, Ryk, receptor-like tyrosine kinase, [Score=202, Expect=9e-57]} {Dmel: FBgn0015380, drl, derailed, [RH, Score=241, Expect=7e-71]} {Celegans: WBGene00003007, lin-18, Inactive tyrosine-protein kinase RYK, [RH, Score=179, Expect=9e-49]} {Smed: dd_Smed_v6_12594_0_3, dd_Smed_v6_12594_0_3, [Score=201, Expect=2e-56]} {RNA1509_58811} {RNA1310_6671.2, RNA1509_58811} {RNA1509_58811, RNA815_41921}
75. MligTC455_09152 404 8.42 Mlig455_017527

Neo: -

Age: -

1.685 - - - 0.956 0.729 - Mlig455_017527 {REF} {Length: 1127} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_58815} {RNA1310_37674} {RNA815_1594}
76. MligTC455_39988 83 1.73 Mlig455_062081

Neo: -

Age: -

1.678 0.955 - - - 0.723 - Mlig455_062081 {REF} {Length: 447} {NoTransDecoderORF} {RNA1509_50426} {RNA1310_88257} {RNA815_17173.4}
77. MligTC455_47459 866 18.03 Mlig455_020310

Neo: -

Age: -

RALGPS1 1.678 0.714 - - 0.964 - - Mlig455_020310 {REF} {Length: 4259} {TRANSSPLICED} {Pfam: RasGEF domain [PF00617.21, score=166.7]} {Human: ENSG00000136828, RALGPS1, Ral GEF with PH domain and SH3 binding motif 1, [RH, Score=278, Expect=2e-83]; ENSG00000116191, RALGPS2, Ral GEF with PH domain and SH3 binding motif 2, [RH, Score=271, Expect=2e-80]} {Mouse: ENSMUSG00000038831, Ralgps1, Ral GEF with PH domain and SH3 binding motif 1, [RH, Score=276, Expect=2e-82]; ENSMUSG00000026594, Ralgps2, Ral GEF with PH domain and SH3 binding motif 2, [RH, Score=271, Expect=7e-82]} {Dmel: FBgn0034158, CG5522, [RH, Score=281, Expect=5e-83]} {Celegans: WBGene00009100, rgef-1, Rap Guanine nucleotide Exchange Factor homolog, [Score=74.3, Expect=2e-13]} {Smed: dd_Smed_v6_9244_0_1, dd_Smed_v6_9244_0_1, [RH, Score=218, Expect=5e-59]} {RNA1509_3628} {RNA1310_3714.1} {RNA815_2665}
78. MligTC455_43590 1860 38.74 Mlig455_035222

Neo: -

Age: -

1.67 - - 0.716 0.954 - - Mlig455_035222 {REF} {Length: 1270} {TRANSSPLICED} {Pfam: Rhodanese-like domain [PF00581.22, score=45.9]} {Dmel: FBgn0039145, CG6000, [RH, Score=73.6, Expect=2e-17]} {Smed: dd_Smed_v6_530_0_1, dd_Smed_v6_530_0_1, [RH, Score=50.4, Expect=1e-08]} {RNA1509_13777, RNA1509_33223, RNA1509_50550, RNA1509_7047, RNA1509_8867} {RNA1310_22990.1, RNA1509_13777, RNA1509_33223, RNA1509_50550, RNA1509_7047, RNA1509_8867} {RNA1509_13777, RNA1509_33223, RNA1509_50550, RNA1509_7047, RNA1509_8867, RNA815_11557}
79. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 1.667 0.963 - - - 0.704 - Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
80. MligTC455_13785 163 3.39 Mlig455_031328

Neo: -

Age: -

MAP3K19 0.999 - - - 0.999 - - Mlig455_031328 {REF} {Length: 3663} {Pfam: Protein kinase domain [PF00069.27, score=168.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=145.5]; Ankyrin repeats (3 copies) [PF12796.9, score=108.7]; Ankyrin repeats (many copies) [PF13637.8, score=103.2]; Ankyrin repeat [PF13606.8, score=54.1]; Ankyrin repeats (many copies) [PF13857.8, score=51.4]; Ankyrin repeat [PF00023.32, score=47.3]; ABC1 atypical kinase-like domain [PF03109.18, score=30.1]; Fungal protein kinase [PF17667.3, score=24.1]; Kinase-like [PF14531.8, score=21.5]; Penicillin-Binding Protein C-terminus Family [PF06832.14, score=19.9]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=167, Expect=7e-42]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=158, Expect=1e-40]} {Dmel: FBgn0014006, Ask1, Apoptotic signal-regulating kinase 1, [Score=133, Expect=1e-31]} {Celegans: WBGene00016038, cst-2, Caenorhabditis STE20-like kinase, [Score=113, Expect=1e-26]} {Smed: dd_Smed_v6_10339_0_1, dd_Smed_v6_10339_0_1, [Score=136, Expect=7e-33]} {RNA1509_41875} {RNA1310_5347} {RNA815_6635.1}
81. MligTC455_46688 341 7.11 Mlig455_064370

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.736

0.997 - - - 0.997 - - Mlig455_064370 {REF} {Length: 4139} {Pfam: MspA [PF09203.13, score=39.4]} {RNA1509_20808, RNA1509_25060} {RNA1310_2880, RNA1509_20808} {RNA1509_20808, RNA815_15411}
82. MligTC455_13060 99 2.06 Mlig455_022766

Neo: -

Age: -

0.996 - - - 0.996 - - Mlig455_022766 {REF} {Length: 787} {NoTransDecoderORF} {RNA1310_132565}
83. MligTC455_18850 747 15.56 Mlig455_066916

Neo: -

Age: -

0.996 - - - 0.996 - - Mlig455_066916 {REF} {Length: 1443} {TRANSSPLICED} {Pfam: SUZ domain [PF12752.9, score=43.3]} {RNA1509_41034} {RNA1310_22799} {RNA815_9711.1}
84. MligTC455_50128 1288 26.83 Mlig455_028373

Neo: -

Age: -

BRAF 0.996 - - - 0.996 - - Mlig455_028373 {REF} {Length: 4173} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=201.0]; Protein kinase domain [PF00069.27, score=178.1]; Raf-like Ras-binding domain [PF02196.17, score=62.7]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=28.8]; Kinase-like [PF14531.8, score=23.0]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [RH, Score=489, Expect=3e-160]} {Mouse: ENSMUSG00000002413, Braf, Braf transforming gene, [RH, Score=488, Expect=7e-160]} {Dmel: FBgn0003079, Raf, Raf oncogene, [RH, Score=373, Expect=2e-116]} {Celegans: WBGene00003030, lin-45, Raf homolog serine/threonine-protein kinase, [RH, Score=342, Expect=5e-104]} {Smed: dd_Smed_v6_10148_0_1, dd_Smed_v6_10148_0_1, [RH, Score=459, Expect=1e-149]} {RNA1509_5530} {RNA1310_8028.1} {RNA815_4195.1}
85. MligTC455_26862 280 5.84 Mlig455_014582

Neo: -

Age: -

0.995 - - - 0.995 - - Mlig455_014582 {REF} {Length: 3135} {TRANSSPLICED} {RNA1509_33062} {RNA1310_8891.1} {RNA815_1626.1}
86. MligTC455_28444 205 4.26 Mlig455_024970, Mlig455_024971

Neo: -

Age: -

0.995 - - - 0.995 - -

Mlig455_024970 {REF} {Length: 899} {NoTransDecoderORF} {RNA1509_9213} {RNA1310_2938.1} {RNA815_14343.2}

Mlig455_024971 {REF} {Length: 1649} {NoTransDecoderORF} {RNA1509_25657} {RNA1310_85415} {RNA815_26110}
87. MligTC455_30921 207 4.31 Mlig455_015986

Neo: -

Age: -

0.995 - - - 0.995 - - Mlig455_015986 {REF} {Length: 3687} {Pfam: Phi29 scaffolding protein [PF11418.10, score=19.3]; Transcriptional regulatory protein LGE1 [PF11488.10, score=19.1]} {RNA1509_29157} {RNA1310_11784} {RNA815_12594}
88. MligTC455_31981 341 7.11 Mlig455_020923

Neo: -

Age: -

DIS3L2 0.995 - - - 0.995 - - Mlig455_020923 {REF} {Length: 724} {Pfam: DIS3-like exonuclease 2 C terminal [PF17877.3, score=42.2]} {Human: ENSG00000144535, DIS3L2, DIS3 like 3'-5' exoribonuclease 2, [Score=50.8, Expect=7e-08]} {Mouse: ENSMUSG00000053333, Dis3l2, DIS3 like 3'-5' exoribonuclease 2, [Score=53.1, Expect=2e-08]} {Celegans: WBGene00018612, disl-2, DIS3-like exonuclease 2, [Score=49.7, Expect=2e-07]} {Smed: dd_Smed_v6_7044_0_1, dd_Smed_v6_7044_0_1, [Score=68.9, Expect=3e-14]} {RNA1509_57497} {RNA1310_4374.3} {RNA815_1234.1}
89. MligTC455_31982 348 7.25 Mlig455_020999

Neo: -

Age: -

DIS3L2 0.995 - - - 0.995 - - Mlig455_020999 {REF} {Length: 2751} {TRANSSPLICED} {Pfam: RNB domain [PF00773.21, score=279.9]; DIS3-like exonuclease 2 C terminal [PF17877.3, score=36.6]; Rrp44-like cold shock domain [PF17216.5, score=27.4]; Dis3-like cold-shock domain 2 (CSD2) [PF17849.3, score=23.3]} {Human: ENSG00000144535, DIS3L2, DIS3 like 3'-5' exoribonuclease 2, [Score=358, Expect=3e-110]} {Mouse: ENSMUSG00000053333, Dis3l2, DIS3 like 3'-5' exoribonuclease 2, [Score=366, Expect=1e-113]} {Dmel: FBgn0035111, Dis3l2, Dis3 like 3'-5' exoribonuclease 2, [Score=254, Expect=2e-71]} {Celegans: WBGene00018612, disl-2, DIS3-like exonuclease 2, [Score=325, Expect=8e-99]} {Smed: dd_Smed_v6_7044_0_1, dd_Smed_v6_7044_0_1, [Score=344, Expect=5e-106]} {RNA1509_57497} {RNA1310_4374.3} {RNA815_1234.1}
90. MligTC455_35070 160 3.34 Mlig455_037630

Neo: -

Age: logFC(26M/2M)=0.479

0.995 - - - 0.995 - - Mlig455_037630 {REF} {Length: 2238} {TRANSSPLICED} {Pfam: Ecdysteroid kinase-like family [PF02958.22, score=94.6]; Protein of unknown function (DUF1679) [PF07914.13, score=32.3]; Phosphotransferase enzyme family [PF01636.25, score=21.9]} {Dmel: FBgn0051974, CG31974, [RH, Score=65.1, Expect=3e-11]} {RNA1509_36549} {RNA1310_22664} {RNA815_13730}
91. MligTC455_41326 407 8.48 Mlig455_011060

Neo: -

Age: -

KCNA2 0.995 - - - 0.995 - - Mlig455_011060 {REF} {Length: 6096} {Pfam: Ion transport protein [PF00520.33, score=161.6]; BTB/POZ domain [PF02214.24, score=99.2]; Ion channel [PF07885.18, score=50.3]} {Human: ENSG00000177301, KCNA2, potassium voltage-gated channel subfamily A member 2, [RH, Score=620, Expect=0.0]; ENSG00000111262, KCNA1, potassium voltage-gated channel subfamily A member 1, [RH, Score=617, Expect=0.0]; ENSG00000177272, KCNA3, potassium voltage-gated channel subfamily A member 3, [RH, Score=611, Expect=0.0]} {Mouse: ENSMUSG00000040724, Kcna2, potassium voltage-gated channel, shaker-related subfamily, member 2, [RH, Score=619, Expect=0.0]; ENSMUSG00000047976, Kcna1, potassium voltage-gated channel, shaker-related subfamily, member 1, [RH, Score=617, Expect=0.0]; ENSMUSG00000047959, Kcna3, potassium voltage-gated channel, shaker-related subfamily, member 3, [RH, Score=607, Expect=0.0]} {Dmel: FBgn0003380, Sh, Shaker, [RH, Score=643, Expect=0.0]} {Celegans: WBGene00014261, shk-1, Potassium voltage-gated channel protein shk-1, [RH, Score=383, Expect=6e-127]} {Smed: dd_Smed_v6_15425_0_1, dd_Smed_v6_15425_0_1, [RH, Score=715, Expect=0.0]} {RNA1509_19798} {RNA1310_8877, RNA1509_19798} {RNA1509_19798, RNA815_8082.1}
92. MligTC455_46515 164 3.41 Mlig455_053726

Neo: -

Age: -

NIPAL2 0.995 - - - 0.995 - - Mlig455_053726 {REF} {Length: 2187} {Pfam: Magnesium transporter NIPA [PF05653.16, score=224.5]; EamA-like transporter family [PF00892.22, score=37.1]} {Human: ENSG00000104361, NIPAL2, NIPA like domain containing 2, [Score=212, Expect=1e-64]} {Mouse: ENSMUSG00000038879, Nipal2, NIPA-like domain containing 2, [Score=200, Expect=2e-60]} {Dmel: FBgn0032451, spict, spichthyin, [Score=82.8, Expect=3e-17]} {Celegans: WBGene00021820, nipa-1, NIPA1 (NonImprinted gene in Prader-Willi/Angelman syndrome region 1) homolog, [Score=127, Expect=8e-33]} {Smed: dd_Smed_v6_7517_0_1, dd_Smed_v6_7517_0_1, [Score=295, Expect=7e-98]} {RNA1509_15001} {RNA1310_12430.1} {RNA815_4380}
93. MligTC455_50129 935 19.48 Mlig455_066199, Mlig455_068834

Neo: -

Age: -

BRAF 0.995 - - - 0.995 - -

Mlig455_066199 {REF} {Length: 4134} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=201.8]; Protein kinase domain [PF00069.27, score=178.9]; Raf-like Ras-binding domain [PF02196.17, score=62.7]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=28.8]; Kinase-like [PF14531.8, score=24.2]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [RH, Score=488, Expect=1e-159]} {Mouse: ENSMUSG00000002413, Braf, Braf transforming gene, [RH, Score=486, Expect=3e-159]} {Dmel: FBgn0003079, Raf, Raf oncogene, [RH, Score=374, Expect=1e-116]} {Celegans: WBGene00003030, lin-45, Raf homolog serine/threonine-protein kinase, [RH, Score=342, Expect=6e-104]} {Smed: dd_Smed_v6_10148_0_1, dd_Smed_v6_10148_0_1, [RH, Score=458, Expect=5e-149]} {RNA1509_5530} {RNA1310_8028.1, RNA1509_5530} {RNA1509_5530, RNA815_4195.1}

Mlig455_068834 {REF} {Length: 4180} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=201.0]; Protein kinase domain [PF00069.27, score=178.1]; Raf-like Ras-binding domain [PF02196.17, score=62.7]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=28.8]; Kinase-like [PF14531.8, score=23.0]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [RH, Score=489, Expect=4e-160]} {Mouse: ENSMUSG00000002413, Braf, Braf transforming gene, [RH, Score=488, Expect=7e-160]} {Dmel: FBgn0003079, Raf, Raf oncogene, [RH, Score=373, Expect=2e-116]} {Celegans: WBGene00003030, lin-45, Raf homolog serine/threonine-protein kinase, [RH, Score=342, Expect=5e-104]} {Smed: dd_Smed_v6_10148_0_1, dd_Smed_v6_10148_0_1, [RH, Score=459, Expect=1e-149]} {RNA1509_5530} {RNA1310_9384} {RNA815_4195.1}
94. MligTC455_51044 1211 25.23 Mlig455_008767, Mlig455_008799

Neo: -

Age: -

OSBPL11 0.995 - - - 0.995 - -

Mlig455_008767 {REF} {Length: 4082} {Pfam: Oxysterol-binding protein [PF01237.20, score=264.7]; PH domain [PF00169.31, score=36.2]; Pleckstrin homology domain [PF15409.8, score=31.3]} {Human: ENSG00000144909, OSBPL11, oxysterol binding protein like 11, [RH, Score=435, Expect=1e-138]; ENSG00000144645, OSBPL10, oxysterol binding protein like 10, [RH, Score=425, Expect=2e-135]} {Mouse: ENSMUSG00000022807, Osbpl11, oxysterol binding protein-like 11, [RH, Score=434, Expect=3e-138]; ENSMUSG00000040875, Osbpl10, oxysterol binding protein-like 10, [RH, Score=425, Expect=8e-137]} {Dmel: FBgn0033463, CG1513, [Score=358, Expect=3e-113]} {Celegans: WBGene00016331, obr-4, Oxysterol-binding protein, [Score=316, Expect=2e-98]} {Smed: dd_Smed_v6_7299_0_1, dd_Smed_v6_7299_0_1, [RH, Score=382, Expect=9e-119]} {RNA1509_10614, RNA1509_25738} {RNA1310_3960.1, RNA1509_25738} {RNA1509_25738, RNA815_2691}

Mlig455_008799 {REF} {Length: 220} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_38576} {RNA1310_3960.1} {RNA815_27097}
95. MligTC455_52703 503 10.48 Mlig455_067967

Neo: -

Age: Up-Down-Up

DSCAM 0.995 - - - 0.995 - - Mlig455_067967 {REF} {Length: 7940} {Pfam: Fibronectin type III domain [PF00041.23, score=181.2]; Immunoglobulin domain [PF13927.8, score=132.1]; Immunoglobulin I-set domain [PF07679.18, score=91.0]; Immunoglobulin domain [PF13895.8, score=77.5]; Immunoglobulin domain [PF00047.27, score=62.1]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=49.3]; Immunoglobulin V-set domain [PF07686.19, score=46.5]} {Human: ENSG00000171587, DSCAM, DS cell adhesion molecule, [RH, Score=242, Expect=2e-63]; ENSG00000177103, DSCAML1, DS cell adhesion molecule like 1, [RH, Score=239, Expect=3e-62]} {Mouse: ENSMUSG00000050272, Dscam, DS cell adhesion molecule, [RH, Score=238, Expect=3e-62]; ENSMUSG00000032087, Dscaml1, DS cell adhesion molecule like 1, [RH, Score=238, Expect=2e-62]} {Dmel: FBgn0263219, Dscam4, Down syndrome cell adhesion molecule 4, [Score=221, Expect=4e-57]} {Celegans: WBGene00004215, ptp-3, Tyrosine-protein phosphatase Lar-like, [Score=79.7, Expect=2e-14]} {Smed: dd_Smed_v6_3024_0_1, dd_Smed_v6_3024_0_1, [RH, Score=330, Expect=1e-90]} {RNA1509_2497} {RNA1310_1699.1} {RNA815_16029}
96. MligTC455_53249 690 14.38 Mlig455_027272, Mlig455_027319

Neo: -

Age: -

Region-enriched R5: 1.274/0.02479

WBP4 0.995 - - - 0.995 - -

Mlig455_027272 {REF} {Length: 1151} {TRANSSPLICED} {Pfam: WW domain [PF00397.28, score=42.3]; U1 zinc finger [PF06220.14, score=41.5]} {Human: ENSG00000120688, WBP4, WW domain binding protein 4, [Score=83.6, Expect=1e-17]} {Mouse: ENSMUSG00000022023, Wbp4, WW domain binding protein 4, [Score=88.6, Expect=1e-19]} {Dmel: FBgn0031287, CG4291, [RH, Score=91.3, Expect=5e-21]} {Smed: dd_Smed_v6_10030_0_6, dd_Smed_v6_10030_0_6, [RH, Score=87.4, Expect=1e-20]} {RNA1509_46002} {RNA1310_29789} {RNA815_12245}

Mlig455_027319 {REF} {Length: 1127} {TRANSSPLICED} {Pfam: WW domain [PF00397.28, score=42.3]; U1 zinc finger [PF06220.14, score=41.5]} {Human: ENSG00000120688, WBP4, WW domain binding protein 4, [Score=81.6, Expect=5e-17]} {Mouse: ENSMUSG00000022023, Wbp4, WW domain binding protein 4, [Score=88.2, Expect=1e-19]} {Dmel: FBgn0031287, CG4291, [RH, Score=91.3, Expect=7e-21]} {Smed: dd_Smed_v6_10030_0_6, dd_Smed_v6_10030_0_6, [RH, Score=87.4, Expect=1e-20]} {RNA1509_46002} {RNA1310_29789} {RNA815_12245}
97. MligTC455_54084 257 5.35 Mlig455_006003

Neo: -

Age: -

0.995 - - - 0.995 - - Mlig455_006003 {REF} {Length: 1037} {RNA1310_44041} {RNA815_43091}
98. MligTC455_00679 246 5.12 Mlig455_028787

Neo: -

Age: -

0.994 - - - 0.994 - - Mlig455_028787 {REF} {Length: 537} {RNA1509_35184} {RNA1310_31249} {RNA815_18932.1}
99. MligTC455_14535 169 3.53 Mlig455_046051

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.630

ANK2 0.994 - - - 0.994 - - Mlig455_046051 {REF} {Length: 4680} {tRNA: Val(CAC),pseudo, score=31.6} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=243.3]; Ankyrin repeats (many copies) [PF13637.8, score=189.3]; Ankyrin repeat [PF00023.32, score=180.0]; Ankyrin repeats (many copies) [PF13857.8, score=142.3]; Ankyrin repeat [PF13606.8, score=133.9]; Caspase domain [PF00656.24, score=116.7]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=177, Expect=1e-44]; ENSG00000151150, ANK3, ankyrin 3, [Score=169, Expect=6e-42]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=172, Expect=7e-43]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=169, Expect=6e-42]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=182, Expect=1e-46]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=168, Expect=4e-42]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=174, Expect=5e-44]} {RNA1509_20997, RNA1509_46578} {RNA1310_3110, RNA1509_20997, RNA1509_46578} {RNA1509_20997, RNA1509_46578, RNA815_5750}
100. MligTC455_16013 376 7.82 Mlig455_002828

Neo: Irradiation

Age: logFC(26M/2M)=0.279

Region-enriched R5: 3.139/0.00000

CCDC102B 0.994 - - - 0.994 - - Mlig455_002828 {REF} {Length: 3370} {TRANSSPLICED} {Human: ENSG00000150636, CCDC102B, coiled-coil domain containing 102B, [Score=78.2, Expect=6e-15]} {Mouse: ENSMUSG00000063605, Ccdc102a, coiled-coil domain containing 102A, [Score=75.5, Expect=1e-13]} {Dmel: FBgn0051638, CG31638, [Score=89.7, Expect=3e-18]} {Celegans: WBGene00018763, F53F10.1, [Score=75.9, Expect=4e-15]} {Smed: dd_Smed_v6_13699_0_1, dd_Smed_v6_13699_0_1, [RH, Score=82.0, Expect=1e-16]} {RNA1509_8054} {RNA1310_7176} {RNA815_2237}

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