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Results for MligTC455_31516

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_31516 251 5.22 Mlig455_070307

Neo: -

Age: Down-Down-Up

Region-enriched R4: 4.340/0.00013
Region-enriched R5: 3.221/0.00026

MTHFD1 Mlig455_070307 {REF} {Length: 3793} {Pfam: Formate--tetrahydrofolate ligase [PF01268.21, score=787.0]; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [PF02882.21, score=216.8]; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [PF00763.25, score=109.7]} {Human: ENSG00000100714, MTHFD1, methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1, [RH, Score=1075, Expect=0.0]} {Mouse: ENSMUSG00000021048, Mthfd1, methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase, [RH, Score=1070, Expect=0.0]} {Dmel: FBgn0020385, pug, pugilist, [RH, Score=1027, Expect=0.0]} {Celegans: WBGene00019492, K07E3.4, [RH, Score=732, Expect=0.0]} {Smed: dd_Smed_v6_1858_0_1, dd_Smed_v6_1858_0_1, [RH, Score=1028, Expect=0.0]} {RNA1509_33432} {RNA1310_1725.1} {RNA815_946}

Cumulative graph for MligTC455_31516

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -5.156 2.986 0.99988 1.00000
RegionR2 -0.18 2.986 0.79699 1.00000
RegionR3 1.661 2.986 0.08732 0.52245
RegionR4 4.34 2.986 0.00001 0.00013
RegionR5 3.221 2.986 0.00001 0.00026
RegionR6 1.762 2.986 0.07837 0.51874
RegionR7 0.073 2.986 0.74254 1.00000
RegionR8 -5.721 2.986 0.99986 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.314 2.986 0.99999 1.00000
RegenerationR2 0.032 2.986 0.96313 1.00000
RegenerationR3 0.204 2.986 0.73961 0.96068
RegenerationR4 -0.038 2.986 0.93095 1.00000
RegenerationR5 0.009 2.986 0.99960 1.00000
RegenerationR6 0.919 2.986 0.12838 0.44034
RegenerationBL 2.47 2.986 0.06099 0.28679
RegenerationTP 2.444 2.986 0.21735 0.66068


Genes with expression patterns similar to MligTC455_31516

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_31516 251 5.22 Mlig455_070307

Neo: -

Age: Down-Down-Up

Region-enriched R4: 4.340/0.00013
Region-enriched R5: 3.221/0.00026

MTHFD1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_070307 {REF} {Length: 3793} {Pfam: Formate--tetrahydrofolate ligase [PF01268.21, score=787.0]; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [PF02882.21, score=216.8]; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [PF00763.25, score=109.7]} {Human: ENSG00000100714, MTHFD1, methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1, [RH, Score=1075, Expect=0.0]} {Mouse: ENSMUSG00000021048, Mthfd1, methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase, [RH, Score=1070, Expect=0.0]} {Dmel: FBgn0020385, pug, pugilist, [RH, Score=1027, Expect=0.0]} {Celegans: WBGene00019492, K07E3.4, [RH, Score=732, Expect=0.0]} {Smed: dd_Smed_v6_1858_0_1, dd_Smed_v6_1858_0_1, [RH, Score=1028, Expect=0.0]} {RNA1509_33432} {RNA1310_1725.1} {RNA815_946}
2. MligTC455_34797 883 18.39 Mlig455_033462

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.410/0.04497

PZP 2.704 - - - 0.894 0.856 0.954 Mlig455_033462 {REF} {Length: 6119} {TRANSSPLICED} {Pfam: A-macroglobulin TED domain [PF07678.16, score=112.0]; A-macroglobulin receptor binding domain [PF07677.16, score=62.2]; Alpha-2-macroglobulin bait region domain [PF07703.16, score=55.9]; Alpha-2-macroglobulin family [PF00207.24, score=45.8]; MG2 domain [PF01835.21, score=35.2]; Macroglobulin domain MG3 [PF17791.3, score=21.3]} {Human: ENSG00000126838, PZP, PZP, alpha-2-macroglobulin like, [Score=179, Expect=2e-44]} {Mouse: ENSMUSG00000030111, A2m, alpha-2-macroglobulin, [Score=174, Expect=3e-43]; ENSMUSG00000030359, Pzp, PZP, alpha-2-macroglobulin like, [Score=171, Expect=3e-42]} {Dmel: FBgn0267488, Mcr, Macroglobulin complement-related, [RH, Score=531, Expect=1e-159]} {Celegans: WBGene00013969, tep-1, TEP (ThiolEster containing Protein), [Score=233, Expect=1e-61]} {Smed: dd_Smed_v6_3070_0_1, dd_Smed_v6_3070_0_1, [RH, Score=1325, Expect=0.0]} {RNA1509_8466} {RNA1310_642.1} {RNA815_286.1}
3. MligTC455_53614 1517 31.61 Mlig455_024547

Neo: -

Age: -

Region-enriched R4: 1.088/0.00445

SLC25A42 2.52 - - - 0.957 0.854 0.709 Mlig455_024547 {REF} {Length: 3477} {TRANSSPLICED} {Pfam: Mitochondrial carrier protein [PF00153.29, score=229.7]} {Human: ENSG00000181035, SLC25A42, solute carrier family 25 member 42, [RH, Score=286, Expect=8e-95]} {Mouse: ENSMUSG00000002346, Slc25a42, solute carrier family 25, member 42, [RH, Score=287, Expect=1e-95]} {Dmel: FBgn0067783, DPCoAC, Dephosphocoenzyme A carrier, [RH, Score=284, Expect=8e-94]} {Celegans: WBGene00009666, slc-25A42, SLC (SoLute Carrier) homolog, [RH, Score=270, Expect=1e-89]} {Smed: dd_Smed_v6_11616_0_1, dd_Smed_v6_11616_0_1, [RH, Score=284, Expect=8e-95]} {RNA1509_13596, RNA1509_35765} {RNA1310_16060, RNA1509_13596, RNA1509_35765} {RNA1509_13596, RNA1509_35765, RNA815_8391}
4. MligTC455_30743 4753 99.02 Mlig455_060907, Mlig455_069368

Neo: S/G2/M, no gonads

Age: Up-Up-Up, logFC(26M/2M)=1.235

Region-specific R5: 2.573

Region-enriched R5: 2.138/0.00000
Region-enriched R4: 1.197/0.00568

Regeneration-upregulated BL: 1.987

Regeneration-enriched BL: 1.987

PIWIL1 1.751 - - - 0.963 0.788 -

Mlig455_060907 {REF} {Length: 3829} {TRANSSPLICED} {Pfam: Piwi domain [PF02171.19, score=257.8]; PAZ domain [PF02170.24, score=99.2]; Argonaute linker 1 domain [PF08699.12, score=33.9]} {Human: ENSG00000125207, PIWIL1, piwi like RNA-mediated gene silencing 1, [RH, Score=573, Expect=0.0]; ENSG00000275051, PIWIL1, piwi like RNA-mediated gene silencing 1, [RH, Score=573, Expect=0.0]} {Mouse: ENSMUSG00000029423, Piwil1, piwi-like RNA-mediated gene silencing 1, [RH, Score=560, Expect=0.0]} {Dmel: FBgn0250816, AGO3, Argonaute 3, [RH, Score=518, Expect=1e-170]} {Celegans: WBGene00004178, prg-1, Piwi-like protein, [RH, Score=417, Expect=1e-132]} {Smed: dd_Smed_v6_1258_0_1, dd_Smed_v6_1258_0_1, [Score=496, Expect=3e-161]} {RNA1509_24273, RNA1509_26947, RNA1509_3900, RNA1509_39890, RNA1509_42423} {RNA1310_4826, RNA1509_24273, RNA1509_26947, RNA1509_39890, RNA1509_42423} {RNA1509_24273, RNA1509_26947, RNA1509_39890, RNA1509_42423, RNA815_813.1}

Mlig455_069368 {REF} {Length: 3825} {TRANSSPLICED} {Pfam: Piwi domain [PF02171.19, score=257.8]; PAZ domain [PF02170.24, score=99.2]; Argonaute linker 1 domain [PF08699.12, score=33.9]} {Human: ENSG00000125207, PIWIL1, piwi like RNA-mediated gene silencing 1, [RH, Score=573, Expect=0.0]; ENSG00000275051, PIWIL1, piwi like RNA-mediated gene silencing 1, [RH, Score=573, Expect=0.0]} {Mouse: ENSMUSG00000029423, Piwil1, piwi-like RNA-mediated gene silencing 1, [RH, Score=560, Expect=0.0]} {Dmel: FBgn0250816, AGO3, Argonaute 3, [RH, Score=518, Expect=1e-170]} {Celegans: WBGene00004178, prg-1, Piwi-like protein, [RH, Score=417, Expect=1e-132]} {Smed: dd_Smed_v6_1258_0_1, dd_Smed_v6_1258_0_1, [Score=496, Expect=3e-161]} {RNA1509_3900} {RNA1310_4826} {RNA815_813.1}
5. MligTC455_43165 376 7.84 Mlig455_039957

Neo: -

Age: -

Region-enriched R3: 1.989/0.00104
Region-enriched R5: 1.524/0.00587

1.679 - - - 0.729 - 0.950 Mlig455_039957 {REF} {Length: 758} {RNA1509_47183, RNA1509_51167, RNA1509_8939} {RNA1310_10828, RNA1509_47183, RNA1509_51167} {RNA1509_47183, RNA1509_51167, RNA815_7128}
6. MligTC455_43214 327 6.8 Mlig455_014195

Neo: -

Age: Down-Down-Up

Region-enriched R6: 1.547/0.04960

ADPRHL1 0.968 - - - - - 0.968 Mlig455_014195 {REF} {Length: 1332} {Human: ENSG00000153531, ADPRHL1, ADP-ribosylhydrolase like 1, [Score=68.2, Expect=1e-11]} {RNA1509_23198} {RNA1310_21075.1} {RNA815_33780}
7. MligTC455_39584 1076 22.42 Mlig455_040074

Neo: Int S/G2/M

Age: -

EIF4EBP2 0.954 - - - 0.954 - - Mlig455_040074 {REF} {Length: 1276} {TRANSSPLICED} {Pfam: Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) [PF05456.13, score=111.2]} {Human: ENSG00000148730, EIF4EBP2, eukaryotic translation initiation factor 4E binding protein 2, [Score=97.1, Expect=3e-26]} {Mouse: ENSMUSG00000020091, Eif4ebp2, eukaryotic translation initiation factor 4E binding protein 2, [Score=94.4, Expect=3e-25]} {Dmel: FBgn0261560, Thor, [Score=67.4, Expect=6e-15]} {Smed: dd_Smed_v6_1204_0_1, dd_Smed_v6_1204_0_1, [Score=76.6, Expect=6e-19]} {RNA1509_17968, RNA1509_42758, RNA1509_50812} {RNA1310_23259, RNA1509_17968, RNA1509_42758, RNA1509_50812} {RNA1509_17968, RNA1509_42758, RNA1509_50812, RNA815_11889.1}
8. MligTC455_23519 291 6.06 Mlig455_043085

Neo: -

Age: logFC(26M/2M)=0.337

Region-enriched R5: 1.705/0.02838

DOLPP1 0.951 - - - - 0.951 - Mlig455_043085 {REF} {Length: 1650} {Pfam: PAP2 superfamily [PF01569.23, score=51.2]} {Human: ENSG00000167130, DOLPP1, dolichyldiphosphatase 1, [Score=117, Expect=6e-33]} {Mouse: ENSMUSG00000026856, Dolpp1, dolichyl pyrophosphate phosphatase 1, [RH, Score=113, Expect=1e-32]} {Smed: dd_Smed_v6_6607_0_1, dd_Smed_v6_6607_0_1, [Score=119, Expect=2e-34]} {RNA1509_22706} {RNA1310_2620} {RNA815_4895}
9. MligTC455_48718 578 12.04 Mlig455_022104

Neo: -

Age: Down-Up-Down

COA4 0.951 - - - - - 0.951 Mlig455_022104 {REF} {Length: 381} {TRANSSPLICED} {Pfam: CHCH domain [PF06747.15, score=23.1]} {Human: ENSG00000181924, COA4, cytochrome c oxidase assembly factor 4 homolog, [RH, Score=64.7, Expect=5e-15]} {Mouse: ENSMUSG00000044881, Coa4, cytochrome c oxidase assembly factor 4, [RH, Score=66.6, Expect=6e-16]} {Dmel: FBgn0265083, CG44194, [RH, Score=60.8, Expect=4e-14]} {Celegans: WBGene00011857, T20D3.3, [RH, Score=61.6, Expect=4e-14]} {Smed: dd_Smed_v6_4811_0_1, dd_Smed_v6_4811_0_1, [RH, Score=62.0, Expect=1e-14]} {RNA1509_14110} {RNA1310_61414} {RNA815_16665.2}

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