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Results for MligTC455_32237

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_32237 1304 27.17 Mlig455_069414

Neo: -

Age: logFC(26M/2M)=-0.427

FRMD5 Mlig455_069414 {REF} {Length: 4538} {TRANSSPLICED} {Pfam: FERM N-terminal domain [PF09379.12, score=46.5]; FERM central domain [PF00373.20, score=45.6]; FERM C-terminal PH-like domain [PF09380.12, score=39.5]} {Human: ENSG00000171877, FRMD5, FERM domain containing 5, [Score=201, Expect=1e-55]} {Mouse: ENSMUSG00000027238, Frmd5, FERM domain containing 5, [Score=199, Expect=3e-55]} {Dmel: FBgn0032225, CG5022, [Score=180, Expect=4e-48]} {Celegans: WBGene00001491, frm-4, FERM domain (Protein4.1-ezrin-radixin-moesin) family, [Score=152, Expect=3e-38]} {Smed: dd_Smed_v6_6227_0_1, dd_Smed_v6_6227_0_1, [Score=266, Expect=5e-79]} {RNA1509_28406} {RNA1310_8453} {RNA815_2005.2}

Cumulative graph for MligTC455_32237

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -2.276 4.832 0.01824 0.37662
RegionR2 0.753 4.832 0.08318 0.35387
RegionR3 0.275 4.832 0.46529 0.97326
RegionR4 -0.126 4.832 0.78792 1.00000
RegionR5 -0.662 4.832 0.10182 0.30876
RegionR6 0.75 4.832 0.04223 0.38492
RegionR7 0.989 4.832 0.01082 0.18093
RegionR8 0.297 4.832 0.52788 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.063 4.832 0.96549 1.00000
RegenerationR2 -0.381 4.832 0.37672 0.79983
RegenerationR3 -0.661 4.832 0.15812 0.59019
RegenerationR4 -0.471 4.832 0.32908 0.76403
RegenerationR5 -0.367 4.832 0.44227 0.82610
RegenerationR6 -1.409 4.832 0.00316 0.06585
RegenerationBL -1.659 4.832 0.00094 0.02191
RegenerationTP -0.452 4.832 0.33561 0.77989


Genes with expression patterns similar to MligTC455_32237

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_32237 1304 27.17 Mlig455_069414

Neo: -

Age: logFC(26M/2M)=-0.427

FRMD5 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_069414 {REF} {Length: 4538} {TRANSSPLICED} {Pfam: FERM N-terminal domain [PF09379.12, score=46.5]; FERM central domain [PF00373.20, score=45.6]; FERM C-terminal PH-like domain [PF09380.12, score=39.5]} {Human: ENSG00000171877, FRMD5, FERM domain containing 5, [Score=201, Expect=1e-55]} {Mouse: ENSMUSG00000027238, Frmd5, FERM domain containing 5, [Score=199, Expect=3e-55]} {Dmel: FBgn0032225, CG5022, [Score=180, Expect=4e-48]} {Celegans: WBGene00001491, frm-4, FERM domain (Protein4.1-ezrin-radixin-moesin) family, [Score=152, Expect=3e-38]} {Smed: dd_Smed_v6_6227_0_1, dd_Smed_v6_6227_0_1, [Score=266, Expect=5e-79]} {RNA1509_28406} {RNA1310_8453} {RNA815_2005.2}
2. MligTC455_52289 1304 27.17 Mlig455_040536, Mlig455_062101

Neo: -

Age: -

Region-enriched R2: 2.340/0.00741

CDH23 3.196 0.730 0.716 - 0.783 0.967 -

Mlig455_040536 {REF} {Length: 5566} {Pfam: Cadherin domain [PF00028.19, score=482.5]; Cadherin-like [PF08266.14, score=52.6]; Cadherin-like [PF16184.7, score=49.2]; RET Cadherin like domain 1 [PF17756.3, score=29.6]; Chlamydia polymorphic membrane protein middle domain [PF07548.13, score=19.7]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=405, Expect=4e-114]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=424, Expect=3e-120]} {Dmel: FBgn0036715, Cad74A, Cadherin 74A, [RH, Score=603, Expect=0.0]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=241, Expect=9e-64]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=291, Expect=2e-79]} {RNA1509_2629, RNA1509_34857} {RNA1310_891, RNA1509_2629, RNA1509_34857} {RNA1509_2629, RNA1509_34857, RNA815_261}

Mlig455_062101 {REF} {Length: 5552} {Pfam: Cadherin domain [PF00028.19, score=474.3]; Cadherin-like [PF08266.14, score=52.6]; Cadherin-like [PF16184.7, score=50.6]; RET Cadherin like domain 1 [PF17756.3, score=28.9]; Chlamydia polymorphic membrane protein middle domain [PF07548.13, score=19.5]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=417, Expect=4e-118]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=416, Expect=1e-117]} {Dmel: FBgn0036715, Cad74A, Cadherin 74A, [RH, Score=600, Expect=0.0]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=230, Expect=2e-60]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=286, Expect=6e-78]} {RNA1509_54845} {RNA1310_830, RNA1509_54845} {RNA1509_54845, RNA815_261}
3. MligTC455_41286 4033 84.01 Mlig455_001654

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.221

2.565 - - 0.786 0.815 0.964 - Mlig455_001654 {REF} {Length: 1603} {Smed: dd_Smed_v6_4625_0_1, dd_Smed_v6_4625_0_1, [RH, Score=148, Expect=4e-44]} {RNA1509_17667, RNA1509_22820, RNA1509_31710, RNA1509_41362, RNA1509_5500} {RNA1310_18662, RNA1509_17667, RNA1509_22820, RNA1509_31710, RNA1509_41362} {RNA1509_17667, RNA1509_22820, RNA1509_31710, RNA1509_41362, RNA815_10004.1}
4. MligTC455_52083 972 20.26 Mlig455_009237, Mlig455_009643

Neo: -

Age: Up-Down-Up

Region-enriched R8: 2.031/0.00909

FAT3 2.523 - - 0.719 - 0.959 0.845

Mlig455_009237 {REF} {Length: 9383} {Pfam: Cadherin domain [PF00028.19, score=291.4]; Laminin G domain [PF02210.26, score=96.4]; Cadherin cytoplasmic region [PF01049.19, score=79.9]; Laminin G domain [PF00054.25, score=77.7]; Cadherin-like [PF16184.7, score=57.2]; Cadherin-like [PF08266.14, score=20.1]} {Human: ENSG00000282908, FAT3, FAT atypical cadherin 3, [Score=286, Expect=3e-76]; ENSG00000165323, FAT3, FAT atypical cadherin 3, [Score=286, Expect=3e-76]} {Mouse: ENSMUSG00000074505, Fat3, FAT atypical cadherin 3, [Score=280, Expect=1e-74]; ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=279, Expect=3e-74]} {Dmel: FBgn0015609, CadN, Cadherin-N, [RH, Score=716, Expect=0.0]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [RH, Score=478, Expect=2e-135]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=175, Expect=4e-43]} {RNA1509_5439} {RNA1310_149} {RNA815_168}

Mlig455_009643 {REF} {Length: 9400} {Pfam: Cadherin domain [PF00028.19, score=300.2]; Laminin G domain [PF02210.26, score=97.0]; Cadherin cytoplasmic region [PF01049.19, score=80.9]; Laminin G domain [PF00054.25, score=78.3]; Cadherin-like [PF16184.7, score=54.5]; Cadherin-like [PF08266.14, score=22.1]} {Human: ENSG00000165323, FAT3, FAT atypical cadherin 3, [Score=280, Expect=2e-74]; ENSG00000282908, FAT3, FAT atypical cadherin 3, [Score=280, Expect=2e-74]} {Mouse: ENSMUSG00000074505, Fat3, FAT atypical cadherin 3, [Score=275, Expect=3e-73]} {Dmel: FBgn0015609, CadN, Cadherin-N, [RH, Score=720, Expect=0.0]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [RH, Score=468, Expect=2e-132]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=169, Expect=1e-41]} {RNA1509_5439} {RNA1310_149, RNA1509_5439} {RNA1509_5439, RNA815_168}
5. MligTC455_29049 441 9.18 Mlig455_042244

Neo: -

Age: -

Region-enriched R2: 4.677/0.00000
Region-enriched R3: 2.595/0.01002

RASGRF1 2.491 - 0.722 - 0.819 0.950 - Mlig455_042244 {REF} {Length: 6465} {Pfam: RasGEF domain [PF00617.21, score=193.2]; RhoGEF domain [PF00621.22, score=119.3]; PH domain [PF00169.31, score=86.7]; RasGEF N-terminal motif [PF00618.22, score=68.4]; Pleckstrin homology domain [PF15413.8, score=22.6]} {Human: ENSG00000058335, RASGRF1, Ras protein specific guanine nucleotide releasing factor 1, [RH, Score=763, Expect=0.0]; ENSG00000113319, RASGRF2, Ras protein specific guanine nucleotide releasing factor 2, [RH, Score=739, Expect=0.0]} {Mouse: ENSMUSG00000032356, Rasgrf1, RAS protein-specific guanine nucleotide-releasing factor 1, [RH, Score=763, Expect=0.0]} {Dmel: FBgn0001965, Sos, Son of sevenless, [Score=164, Expect=3e-40]} {Celegans: WBGene00004947, sos-1, Son of sevenless homolog, [Score=118, Expect=3e-26]} {Smed: dd_Smed_v6_18313_0_2, dd_Smed_v6_18313_0_2, [RH, Score=1137, Expect=0.0]} {RNA1509_15697} {RNA1310_2543.1} {RNA815_8228.1}
6. MligTC455_33343 459 9.56 Mlig455_063303

Neo: -

Age: -

Region-enriched R2: 1.600/0.01675

ITPR1 2.483 0.734 0.792 - - 0.957 - Mlig455_063303 {REF} {Length: 3962} {Pfam: RyR and IP3R Homology associated [PF08454.13, score=68.3]; Ion transport protein [PF00520.33, score=28.7]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=166, Expect=6e-41]} {Mouse: ENSMUSG00000030102, Itpr1, inositol 1,4,5-trisphosphate receptor 1, [Score=182, Expect=7e-46]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=179, Expect=4e-45]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=155, Expect=5e-38]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1044, Expect=0.0]} {RNA1509_30811} {RNA1310_939} {RNA815_220}
7. MligTC455_36816 362 7.54 Mlig455_027841, Mlig455_060008

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.712

ANK3 1.804 - - - - 0.977 0.827

Mlig455_027841 {REF} {Length: 5725} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=91.6]; Protein of unknown function (DUF3421) [PF11901.10, score=84.7]; Ankyrin repeats (many copies) [PF13637.8, score=72.1]; Ankyrin repeats (many copies) [PF13857.8, score=49.2]; Ankyrin repeat [PF13606.8, score=41.0]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=55.5, Expect=1e-06]} {Mouse: ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=62.4, Expect=5e-09]} {Dmel: FBgn0034583, CG10527, [Score=93.6, Expect=3e-20]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=81.3, Expect=5e-15]} {Smed: dd_Smed_v6_766_0_1, dd_Smed_v6_766_0_1, [Score=118, Expect=2e-30]} {RNA1509_30268} {RNA1310_2381} {RNA815_861}

Mlig455_060008 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=93.3]; Ankyrin repeats (many copies) [PF13637.8, score=74.1]; Ankyrin repeats (many copies) [PF13857.8, score=51.3]; Ankyrin repeat [PF13606.8, score=43.0]; Ankyrin repeat [PF00023.32, score=19.4]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=53.5, Expect=3e-06]} {Mouse: ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=61.2, Expect=8e-09]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=52.0, Expect=5e-06]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=80.5, Expect=8e-15]} {Smed: dd_Smed_v6_13721_0_1, dd_Smed_v6_13721_0_1, [Score=59.3, Expect=1e-08]} {RNA1509_30268} {RNA1310_2381} {RNA815_861}
8. MligTC455_47077 2580 53.76 Mlig455_064646

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.455

1.767 - - 0.810 - 0.957 - Mlig455_064646 {REF} {Length: 600} {NoTransDecoderORF} {RNA1509_1238, RNA1509_26503} {RNA1310_868, RNA1509_1238, RNA1509_26503} {RNA1509_1238, RNA1509_26503, RNA815_1694.1}
9. MligTC455_31766 406 8.46 Mlig455_006320

Neo: -

Age: logFC(26M/2M)=-0.931

Region-enriched R8: 3.096/0.00108

LMNB1 1.755 0.782 - - - 0.973 - Mlig455_006320 {REF} {Length: 1848} {Pfam: Intermediate filament protein [PF00038.23, score=149.5]} {Human: ENSG00000113368, LMNB1, lamin B1, [Score=110, Expect=3e-25]; ENSG00000160789, LMNA, lamin A/C, [Score=105, Expect=4e-23]} {Mouse: ENSMUSG00000024590, Lmnb1, lamin B1, [Score=109, Expect=9e-25]; ENSMUSG00000028063, Lmna, lamin A, [Score=104, Expect=4e-23]} {Dmel: FBgn0010397, LamC, Lamin C, [Score=123, Expect=1e-29]} {Celegans: WBGene00002050, ifa-1, Intermediate filament protein ifa-1, [Score=233, Expect=3e-69]} {Smed: dd_Smed_v6_3871_0_1, dd_Smed_v6_3871_0_1, [Score=276, Expect=8e-86]} {RNA1509_32226} {RNA1310_5840} {RNA815_9167}
10. MligTC455_19277 1013 21.11 Mlig455_059600

Neo: -

Age: -

Region-specific R2: 4.883

Region-enriched R2: 5.766/0.00000
Region-enriched R3: 2.030/0.00976

1.741 - - - 0.788 0.953 - Mlig455_059600 {REF} {Length: 827} {NoTransDecoderORF} {RNA1509_43907} {RNA1310_81348}
11. MligTC455_33808 22456 467.83 Mlig455_061945

Neo: -

Age: -

MOXD1 1.732 0.777 - - - 0.955 - Mlig455_061945 {REF} {Length: 2202} {TRANSSPLICED} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=92.1]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=68.1]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=120, Expect=5e-28]; ENSG00000123454, DBH, dopamine beta-hydroxylase, [Score=117, Expect=7e-27]} {Mouse: ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=135, Expect=5e-33]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=127, Expect=1e-30]} {Celegans: WBGene00006541, tbh-1, Tyramine beta-hydroxylase, [Score=139, Expect=7e-35]} {Smed: dd_Smed_v6_42610_0_1, dd_Smed_v6_42610_0_1, [Score=118, Expect=8e-29]} {RNA1509_127} {RNA1310_11166.1} {RNA815_4383.1}
12. MligTC455_35478 597 12.43 Mlig455_020720, Mlig455_020788

Neo: -

Age: logFC(26M/2M)=0.408

1.721 - - 0.762 - 0.959 -

Mlig455_020720 {REF} {Length: 1135} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_13719} {RNA1310_25325} {RNA815_14669}

Mlig455_020788 {REF} {Length: 1139} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_13719} {RNA1310_25325} {RNA815_14669}
13. MligTC455_44432 1115 23.23 Mlig455_015671, Mlig455_062480

Neo: -

Age: logFC(26M/2M)=0.247

F5 1.72 - 0.762 - - 0.958 -

Mlig455_015671 {REF} {Length: 5764} {Pfam: F5/8 type C domain [PF00754.27, score=47.5]} {Human: ENSG00000198734, F5, coagulation factor V, [Score=64.3, Expect=2e-09]; ENSG00000185010, F8, coagulation factor VIII, [Score=62.8, Expect=6e-09]} {Mouse: ENSMUSG00000031196, F8, coagulation factor VIII, [Score=69.3, Expect=4e-11]} {Dmel: FBgn0053531, Ddr, Discoidin domain receptor, [Score=50.8, Expect=6e-06]} {Smed: dd_Smed_v6_15631_0_1, dd_Smed_v6_15631_0_1, [Score=87.8, Expect=3e-17]} {RNA1509_2035} {RNA1310_951.1, RNA1509_2035} {RNA1509_2035, RNA815_305}

Mlig455_062480 {REF} {Length: 6260} {Pfam: F5/8 type C domain [PF00754.27, score=47.5]} {Human: ENSG00000198734, F5, coagulation factor V, [Score=64.7, Expect=2e-09]; ENSG00000185010, F8, coagulation factor VIII, [Score=62.0, Expect=1e-08]} {Mouse: ENSMUSG00000031196, F8, coagulation factor VIII, [Score=68.2, Expect=9e-11]} {Dmel: FBgn0053531, Ddr, Discoidin domain receptor, [Score=53.5, Expect=1e-06]} {Smed: dd_Smed_v6_15631_0_1, dd_Smed_v6_15631_0_1, [Score=89.7, Expect=8e-18]} {RNA1509_2035, RNA1509_37215} {RNA1310_951.1, RNA1509_37215} {RNA1509_37215, RNA815_305}
14. MligTC455_49394 1184 24.68 Mlig455_041577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.255/0.02823

1.698 - - - - 0.977 0.721 Mlig455_041577 {REF} {Length: 928} {Pfam: Normal lung function maintenance, Low in Lung Cancer 1 protein [PF14945.8, score=24.7]} {Smed: dd_Smed_v6_6024_0_1, dd_Smed_v6_6024_0_1, [Score=97.8, Expect=1e-26]} {RNA1509_17780, RNA1509_38038} {RNA1310_47454, RNA1509_17780, RNA1509_38038} {RNA1509_17780, RNA1509_38038, RNA815_24792.1}
15. MligTC455_31117 933 19.44 Mlig455_017721, Mlig455_057064, Mlig455_057078

Neo: -

Age: logFC(26M/2M)=-0.670

Region-enriched R2: 1.818/0.04375

ADAM33, ADAM9 1.669 - - 0.713 - 0.956 -

Mlig455_017721 {REF} {Length: 3292} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=127.8]; Metallo-peptidase family M12 [PF13688.8, score=71.8]; Disintegrin [PF00200.25, score=68.3]; ADAM cysteine-rich [PF08516.14, score=60.1]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=40.8]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=37.1]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=30.2]; Matrixin [PF00413.26, score=19.9]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [RH, Score=244, Expect=5e-69]} {Mouse: ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [RH, Score=254, Expect=3e-73]; ENSMUSG00000050190, Gm5346, predicted gene 5346, [RH, Score=251, Expect=7e-72]} {Dmel: FBgn0265140, Meltrin, [Score=272, Expect=3e-78]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [RH, Score=251, Expect=5e-71]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=225, Expect=1e-61]} {RNA1509_21514, RNA1509_7654} {RNA1310_9319.1, RNA1509_21514, RNA1509_7654} {RNA1509_21514, RNA1509_7654, RNA815_4173.1}

Mlig455_057064 {REF} {Length: 3604} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=128.4]; Metallo-peptidase family M12 [PF13688.8, score=69.3]; Disintegrin [PF00200.25, score=68.6]; ADAM cysteine-rich [PF08516.14, score=60.7]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=42.0]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=37.2]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=31.5]; Matrixin [PF00413.26, score=19.9]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [RH, Score=247, Expect=9e-71]} {Mouse: ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=256, Expect=1e-74]} {Dmel: FBgn0265140, Meltrin, [Score=270, Expect=2e-78]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=248, Expect=7e-71]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=226, Expect=7e-63]} {RNA1509_44914} {RNA1310_9319.1, RNA1509_44914} {RNA1509_44914, RNA815_4173.1}

Mlig455_057078 {REF} {Length: 1339} {Pfam: ADAM cysteine-rich [PF08516.14, score=75.6]; Disintegrin [PF00200.25, score=53.3]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=145, Expect=6e-38]; ENSG00000168594, ADAM29, ADAM metallopeptidase domain 29, [Score=145, Expect=1e-37]; ENSG00000139985, ADAM21, ADAM metallopeptidase domain 21, [Score=143, Expect=5e-37]; ENSG00000143537, ADAM15, ADAM metallopeptidase domain 15, [Score=142, Expect=8e-37]} {Mouse: ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=137, Expect=5e-35]; ENSMUSG00000028041, Adam15, a disintegrin and metallopeptidase domain 15 (metargidin), [Score=137, Expect=3e-35]; ENSMUSG00000011256, Adam19, a disintegrin and metallopeptidase domain 19 (meltrin beta), [Score=137, Expect=3e-35]; ENSMUSG00000046258, Adam29, a disintegrin and metallopeptidase domain 29, [Score=137, Expect=3e-35]; ENSMUSG00000008438, Adam21, a disintegrin and metallopeptidase domain 21, [Score=135, Expect=2e-34]; ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [Score=134, Expect=5e-34]; ENSMUSG00000062438, Adam1b, a disintegrin and metallopeptidase domain 1b, [Score=134, Expect=3e-34]; ENSMUSG00000031553, Adam3, a disintegrin and metallopeptidase domain 3 (cyritestin), [Score=133, Expect=1e-33]; ENSMUSG00000063900, Adam26b, a disintegrin and metallopeptidase domain 26B, [Score=131, Expect=3e-33]} {Dmel: FBgn0265140, Meltrin, [Score=153, Expect=1e-40]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=133, Expect=6e-34]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=132, Expect=1e-33]} {RNA1509_44914} {RNA1310_9319.1} {RNA815_4173.1}
16. MligTC455_19276 1694 35.28 Mlig455_057303

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.711

Region-enriched R2: 6.117/0.00000
Region-enriched R3: 2.663/0.00058

1.654 - - - 0.703 0.951 - Mlig455_057303 {REF} {Length: 1196} {Pfam: TATA-binding related factor (TRF) of subunit 20 of Mediator complex [PF08612.13, score=80.6]} {Smed: dd_Smed_v6_9879_0_1, dd_Smed_v6_9879_0_1, [RH, Score=73.9, Expect=1e-15]} {RNA1509_58478} {RNA1310_35292} {RNA815_20171}
17. MligTC455_30617 647 13.47 Mlig455_031164

Neo: -

Age: logFC(26M/2M)=-0.513

ITPR1 1.652 - - 0.701 - 0.951 - Mlig455_031164 {REF} {Length: 3978} {Pfam: RyR and IP3R Homology associated [PF08454.13, score=75.9]; Ion transport protein [PF00520.33, score=29.6]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=157, Expect=3e-38]} {Mouse: ENSMUSG00000057378, Ryr3, ryanodine receptor 3, [Score=149, Expect=6e-36]; ENSMUSG00000030592, Ryr1, ryanodine receptor 1, skeletal muscle, [Score=148, Expect=1e-35]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=137, Expect=2e-32]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=127, Expect=1e-29]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=598, Expect=0.0]} {RNA1509_42170} {RNA1310_129.1} {RNA815_62.1}
18. MligTC455_31833 605 12.6 Mlig455_044603

Neo: -

Age: Down-Up-Down

RNF11 0.987 - - - - 0.987 - Mlig455_044603 {REF} {Length: 3405} {Pfam: Ring finger domain [PF13639.8, score=45.9]; RING-like zinc finger [PF17123.7, score=42.2]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=31.1]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=30.0]; RING-type zinc-finger [PF13445.8, score=27.5]; RING-H2 zinc finger domain [PF12678.9, score=27.4]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=27.1]; zinc-RING finger domain [PF14634.8, score=25.9]; Zinc-ribbon, C4HC2 type [PF17120.7, score=21.8]; Prokaryotic RING finger family 4 [PF14447.8, score=20.2]} {Human: ENSG00000123091, RNF11, ring finger protein 11, [RH, Score=139, Expect=3e-42]} {Mouse: ENSMUSG00000028557, Rnf11, ring finger protein 11, [RH, Score=140, Expect=1e-42]} {Dmel: FBgn0052850, CG32850, [RH, Score=114, Expect=7e-33]} {Celegans: WBGene00007226, C01G6.4, [RH, Score=92.4, Expect=4e-24]} {Smed: dd_Smed_v6_6913_0_1, dd_Smed_v6_6913_0_1, [RH, Score=125, Expect=3e-36]} {RNA1509_18116, RNA1509_21679, RNA1509_27882, RNA1509_37366, RNA1509_56350} {RNA1310_15427, RNA1509_18116, RNA1509_21679, RNA1509_27882, RNA1509_37366, RNA1509_56350} {RNA1509_18116, RNA1509_21679, RNA1509_27882, RNA1509_37366, RNA1509_56350, RNA815_8337.1}
19. MligTC455_40038 463 9.64 Mlig455_044413

Neo: -

Age: Down-Up-Up

0.984 - - - - 0.984 - Mlig455_044413 {REF} {Length: 1167} {Pfam: Fruit fly transformer protein [PF06495.13, score=22.2]; Ets-domain [PF00178.24, score=22.0]; Coronavirus nucleocapsid [PF00937.20, score=18.0]} {RNA1509_38421, RNA1509_58641} {RNA1310_33082, RNA1509_38421, RNA1509_58641} {RNA1509_38421, RNA1509_58641, RNA815_26283}
20. MligTC455_49730 949 19.77 Mlig455_018448

Neo: -

Age: logFC(26M/2M)=-0.195

Region-enriched R2: 1.188/0.02467

TNKS 0.984 - - - - 0.984 - Mlig455_018448 {REF} {Length: 3480} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=75.2]; Ion transport protein [PF00520.33, score=64.2]; Ankyrin repeats (many copies) [PF13857.8, score=59.3]; Ankyrin repeat [PF13606.8, score=53.2]; Ankyrin repeat [PF00023.32, score=51.3]; Ankyrin repeats (many copies) [PF13637.8, score=51.3]; Polycystin cation channel [PF08016.14, score=19.7]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=89.4, Expect=2e-17]; ENSG00000285372, AC270292.3, tankyrase, [Score=89.0, Expect=3e-17]; ENSG00000135299, ANKRD6, ankyrin repeat domain 6, [Score=87.4, Expect=5e-18]} {Mouse: ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=89.0, Expect=2e-17]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=83.6, Expect=6e-16]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=90.9, Expect=2e-18]} {Smed: dd_Smed_v6_10764_0_3, dd_Smed_v6_10764_0_3, [Score=80.9, Expect=1e-15]} {RNA1509_23119, RNA1509_31186, RNA1509_44376} {RNA1310_4706, RNA1509_23119, RNA1509_31186, RNA1509_44376} {RNA1509_23119, RNA1509_31186, RNA1509_44376, RNA815_1228}
21. MligTC455_28203 264 5.51 Mlig455_063892

Neo: -

Age: Down-Up-Down

0.982 - - - - 0.982 - Mlig455_063892 {REF} {Length: 889} {Smed: dd_Smed_v6_6429_0_1, dd_Smed_v6_6429_0_1, [Score=99.0, Expect=5e-22]} {RNA1509_9848} {RNA1310_13445} {RNA815_20358}
22. MligTC455_52873 251 5.23 Mlig455_038881, Mlig455_063845

Neo: -

Age: Up-Down-Up

PRR9 0.977 - - - - 0.977 -

Mlig455_038881 {REF} {Length: 2672} {RNA1509_23775} {RNA1310_21973} {RNA815_6939}

Mlig455_063845 {REF} {Length: 778} {Human: ENSG00000203783, PRR9, proline rich 9, [Score=44.3, Expect=5e-06]} {Celegans: WBGene00018026, F35A5.4, [Score=43.5, Expect=1e-05]} {RNA1310_21973}
23. MligTC455_37111 1709 35.61 Mlig455_015739, Mlig455_049445, Mlig455_049459

Neo: -

Age: logFC(26M/2M)=-0.249

Region-enriched R2: 1.162/0.04679

0.975 - - - - 0.975 -

Mlig455_015739 {REF} {Length: 1115} {RNA1509_33493} {RNA1310_28591.1} {RNA815_13812.1}

Mlig455_049445 {REF} {Length: 1524} {RNA1509_21694, RNA1509_33493} {RNA1310_28591.1, RNA1509_21694, RNA1509_33493} {RNA1509_21694, RNA1509_33493, RNA815_13812.1}

Mlig455_049459 {REF} {Length: 2200} {RNA1509_21694} {RNA1310_28591.1} {RNA815_13812.1}
24. MligTC455_44111 3831 79.82 Mlig455_013954, Mlig455_039337

Neo: -

Age: -

Region-enriched R7: 1.370/0.00005

Regeneration-downregulated BL: -1.383

Regeneration-depleted BL: -1.383

0.975 - - - - 0.975 -

Mlig455_013954 {REF} {Length: 1658} {Pfam: Spt5 C-terminal nonapeptide repeat binding Spt4 [PF12815.9, score=27.4]} {RNA1509_27811} {RNA1310_38290} {RNA815_35587}

Mlig455_039337 {REF} {Length: 2053} {RNA1509_27811, RNA1509_47914} {RNA1310_38290, RNA1509_47914} {RNA1509_47914, RNA815_35587}
25. MligTC455_42646 265 5.53 Mlig455_046692

Neo: -

Age: -

Region-enriched R2: 2.509/0.02015

KRT8 0.97 - - - - 0.970 - Mlig455_046692 {REF} {Length: 3581} {TRANSSPLICED} {Pfam: Intermediate filament protein [PF00038.23, score=144.4]; Protein of unknown function (DUF3450) [PF11932.10, score=22.6]; BRE1 E3 ubiquitin ligase [PF08647.13, score=19.7]; Bacillus haemolytic enterotoxin (HBL) [PF05791.13, score=18.9]; Afadin- and alpha -actinin-Binding [PF11559.10, score=18.7]; Crescentin protein [PF19220.2, score=18.6]} {Human: ENSG00000170421, KRT8, keratin 8, [RH, Score=111, Expect=2e-25]} {Mouse: ENSMUSG00000063661, Krt73, keratin 73, [RH, Score=107, Expect=3e-24]} {Dmel: FBgn0010397, LamC, Lamin C, [Score=140, Expect=4e-35]} {Celegans: WBGene00002050, ifa-1, Intermediate filament protein ifa-1, [Score=251, Expect=7e-76]} {Smed: dd_Smed_v6_3871_0_1, dd_Smed_v6_3871_0_1, [Score=275, Expect=4e-85]} {RNA1310_10400} {RNA815_12264}
26. MligTC455_13847 144 3 Mlig455_005556

Neo: -

Age: logFC(26M/2M)=-0.534

Region-enriched R2: 3.307/0.04973

TEKT3 0.968 - - - - 0.968 - Mlig455_005556 {REF} {Length: 3025} {Pfam: Tektin family [PF03148.16, score=370.9]} {Human: ENSG00000125409, TEKT3, tektin 3, [Score=286, Expect=7e-91]} {Mouse: ENSMUSG00000042189, Tekt3, tektin 3, [Score=269, Expect=2e-84]} {Dmel: FBgn0052819, CG32819, [Score=201, Expect=2e-58]} {Smed: dd_Smed_v6_6511_0_1, dd_Smed_v6_6511_0_1, [Score=329, Expect=4e-108]} {RNA1509_15766} {RNA1310_13406} {RNA815_7559}
27. MligTC455_51207 1231 25.65 Mlig455_019925, Mlig455_047946

Neo: -

Age: -

MCTP1 0.966 - - - - 0.966 -

Mlig455_019925 {REF} {Length: 6036} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=305.3]} {Human: ENSG00000175471, MCTP1, multiple C2 and transmembrane domain containing 1, [Score=117, Expect=6e-26]} {Mouse: ENSMUSG00000032776, Mctp2, multiple C2 domains, transmembrane 2, [Score=114, Expect=4e-25]; ENSMUSG00000021596, Mctp1, multiple C2 domains, transmembrane 1, [Score=111, Expect=3e-24]} {Dmel: FBgn0034389, Mctp, Multiple C2 domain and transmembrane region protein, [Score=78.2, Expect=4e-14]} {Celegans: WBGene00004922, snt-2, Synaptotagmin 2, [Score=64.7, Expect=2e-10]} {Smed: dd_Smed_v6_13224_0_1, dd_Smed_v6_13224_0_1, [RH, Score=158, Expect=4e-39]} {RNA1509_4129} {RNA1310_1165.1} {RNA815_1160}

Mlig455_047946 {REF} {Length: 6306} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=305.4]} {Human: ENSG00000175471, MCTP1, multiple C2 and transmembrane domain containing 1, [Score=116, Expect=1e-25]} {Mouse: ENSMUSG00000021596, Mctp1, multiple C2 domains, transmembrane 1, [Score=111, Expect=4e-24]; ENSMUSG00000032776, Mctp2, multiple C2 domains, transmembrane 2, [Score=109, Expect=2e-23]} {Dmel: FBgn0039900, Syt7, Synaptotagmin 7, [Score=70.9, Expect=2e-12]} {Celegans: WBGene00004923, snt-3, SyNapTotagmin, [Score=68.2, Expect=7e-12]} {Smed: dd_Smed_v6_13224_0_1, dd_Smed_v6_13224_0_1, [RH, Score=158, Expect=4e-39]} {RNA1509_4129} {RNA1310_1165.1} {RNA815_1160}
28. MligTC455_49393 893 18.6 Mlig455_003601

Neo: -

Age: -

Region-enriched R2: 1.237/0.01562

Regeneration-downregulated BL: -2.400

Regeneration-depleted BL: -2.400

0.964 - - - - 0.964 - Mlig455_003601 {REF} {Length: 910} {Pfam: Normal lung function maintenance, Low in Lung Cancer 1 protein [PF14945.8, score=24.4]} {Smed: dd_Smed_v6_6024_0_1, dd_Smed_v6_6024_0_1, [Score=98.6, Expect=5e-27]} {RNA1509_38038} {RNA1310_47454} {RNA815_24792.1}
29. MligTC455_21848 38 0.78 Mlig455_052292

Neo: -

Age: -

0.963 - - - - 0.963 - Mlig455_052292 {REF} {Length: 1664} {NoTransDecoderORF} {RNA1509_40232} {RNA1310_50.3} {RNA815_40347}
30. MligTC455_26269 294 6.12 Mlig455_056660

Neo: -

Age: Up-Up-Down

0.963 - - - - 0.963 - Mlig455_056660 {REF} {Length: 6926} {Pfam: Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=24.3]} {RNA1509_47204, RNA1509_52342, RNA1509_55209} {RNA1310_5450.1, RNA1509_47204, RNA1509_52342, RNA1509_55209} {RNA1509_47204, RNA1509_52342, RNA1509_55209, RNA815_7136.2}
31. MligTC455_29581 375 7.82 Mlig455_004723

Neo: -

Age: -

Region-enriched R2: 1.878/0.02571

AP1S2 0.963 - - - - 0.963 - Mlig455_004723 {REF} {Length: 1824} {TRANSSPLICED} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=193.6]} {Human: ENSG00000182287, AP1S2, adaptor related protein complex 1 subunit sigma 2, [RH, Score=270, Expect=7e-94]; ENSG00000106367, AP1S1, adaptor related protein complex 1 subunit sigma 1, [RH, Score=263, Expect=6e-91]} {Mouse: ENSMUSG00000031367, Ap1s2, adaptor-related protein complex 1, sigma 2 subunit, [RH, Score=270, Expect=5e-94]; ENSMUSG00000004849, Ap1s1, adaptor protein complex AP-1, sigma 1, [RH, Score=263, Expect=4e-91]} {Dmel: FBgn0039132, AP-1sigma, Adaptor Protein complex 1, sigma subunit, [RH, Score=262, Expect=3e-91]} {Celegans: WBGene00000159, aps-1, AdaPtin, Small chain (Clathrin associated complex), [Score=256, Expect=8e-89]} {Smed: dd_Smed_v6_9393_0_2, dd_Smed_v6_9393_0_2, [RH, Score=263, Expect=1e-91]} {RNA1509_14918} {RNA1310_7376.1} {RNA815_4627}
32. MligTC455_40039 210 4.37 Mlig455_044449

Neo: -

Age: Down-Up-Up

0.963 - - - - 0.963 - Mlig455_044449 {REF} {Length: 1349} {Pfam: Ets-domain [PF00178.24, score=21.9]} {RNA1509_38421} {RNA1310_33082} {RNA815_26283}
33. MligTC455_22569 338 7.03 Mlig455_006660

Neo: -

Age: -

0.962 - - - - 0.962 - Mlig455_006660 {REF} {Length: 4485} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=28.7]; Ankyrin repeats (3 copies) [PF12796.9, score=26.1]; Ankyrin repeats (many copies) [PF13857.8, score=22.7]; Ankyrin repeat [PF13606.8, score=20.1]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=50.1, Expect=6e-06]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=48.9, Expect=6e-06]} {RNA1509_12214} {RNA1310_987} {RNA815_3324}
34. MligTC455_52964 2243 46.73 Mlig455_014502, Mlig455_014522, Mlig455_054426

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=1.246

Regeneration-depleted R6: -4.281
Regeneration-depleted BL: -3.394

0.962 - - - - 0.962 -

Mlig455_014502 {REF} {Length: 1470} {RNA1509_32913, RNA1509_42868, RNA1509_59081} {RNA1310_20121.1, RNA1509_32913, RNA1509_59081} {RNA1509_32913, RNA1509_59081, RNA815_10681.1}

Mlig455_014522 {REF} {Length: 1481} {RNA1509_42868} {RNA1310_20121.1} {RNA815_10681.1}

Mlig455_054426 {REF} {Length: 1481} {RNA1509_42868} {RNA1310_20121.1, RNA1509_42868} {RNA1509_42868, RNA815_10681.1}
35. MligTC455_18648 470 9.79 Mlig455_063464

Neo: -

Age: logFC(26M/2M)=-0.661

0.961 - - - - 0.961 - Mlig455_063464 {REF} {Length: 1671} {Pfam: BTB/POZ domain [PF00651.33, score=33.9]} {RNA1509_21795, RNA1509_45066} {RNA1310_23212, RNA1509_21795} {RNA1509_21795, RNA815_2283.1}
36. MligTC455_40123 4975 103.64 Mlig455_016241

Neo: -

Age: -

Region-enriched R2: 1.124/0.00040

RPLP1 0.961 - - - - 0.961 - Mlig455_016241 {REF} {Length: 1464} {TRANSSPLICED} {Pfam: 60s Acidic ribosomal protein [PF00428.21, score=72.7]; Cytomegalovirus UL84 protein [PF06284.13, score=17.3]} {Human: ENSG00000137818, RPLP1, ribosomal protein lateral stalk subunit P1, [Score=69.3, Expect=7e-16]} {Mouse: ENSMUSG00000007892, Rplp1, ribosomal protein, large, P1, [Score=68.6, Expect=8e-16]; ENSMUSG00000060019, Gm10073, predicted pseudogene 10073, [Score=66.2, Expect=8e-15]} {Dmel: FBgn0002593, RpLP1, Ribosomal protein LP1, [Score=79.0, Expect=5e-20]} {Celegans: WBGene00004409, rla-1, 60S acidic ribosomal protein P1, [Score=75.5, Expect=1e-18]} {Smed: dd_Smed_v6_224_0_1, dd_Smed_v6_224_0_1, [Score=67.4, Expect=1e-15]} {RNA1509_13266, RNA1509_14665, RNA1509_28604} {RNA1310_21379.1, RNA1509_13266, RNA1509_14665, RNA1509_28604} {RNA1509_13266, RNA1509_14665, RNA1509_28604, RNA815_9430.1}
37. MligTC455_29828 3825 79.69 Mlig455_005927, Mlig455_028571

Neo: -

Age: -

Region-enriched R2: 2.078/0.00752

AOX1 0.96 - - - - 0.960 -

Mlig455_005927 {REF} {Length: 5419} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=393.8]; [2Fe-2S] binding domain [PF01799.22, score=95.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=88.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=82.6]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=60.0]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=21.6]} {Human: ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=461, Expect=1e-139]; ENSG00000158125, XDH, xanthine dehydrogenase, [Score=454, Expect=4e-137]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=468, Expect=2e-142]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=449, Expect=1e-135]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=665, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=506, Expect=1e-156]} {RNA1509_1345} {RNA1310_1703.1, RNA1509_1345} {RNA1509_1345, RNA815_528.1}

Mlig455_028571 {REF} {Length: 5081} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=393.8]; [2Fe-2S] binding domain [PF01799.22, score=95.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=88.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=82.6]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=60.0]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=21.6]} {Human: ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=459, Expect=5e-139]; ENSG00000158125, XDH, xanthine dehydrogenase, [Score=453, Expect=6e-137]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=467, Expect=3e-142]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=450, Expect=9e-136]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=665, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=506, Expect=1e-156]} {RNA1509_1345, RNA1509_30386} {RNA1310_1703.1, RNA1509_30386} {RNA1509_30386, RNA815_528.1}
38. MligTC455_39235 523 10.9 Mlig455_058236

Neo: -

Age: logFC(26M/2M)=-0.695

MUC4 0.96 - - - - 0.960 - Mlig455_058236 {REF} {Length: 9547} {Pfam: Calcium-binding EGF domain [PF07645.17, score=73.7]; EGF-like domain [PF00008.29, score=73.3]; Complement Clr-like EGF-like [PF12662.9, score=63.6]; von Willebrand factor type D domain [PF00094.27, score=52.5]; Human growth factor-like EGF [PF12661.9, score=44.5]; EGF domain [PF12947.9, score=44.1]; Coagulation Factor Xa inhibitory site [PF14670.8, score=33.7]; Nidogen-like [PF06119.16, score=22.0]; MSP1 EGF domain 1 [PF12946.9, score=21.2]} {Human: ENSG00000277585, MUC4, mucin 4, cell surface associated, [Score=175, Expect=8e-43]; ENSG00000276613, MUC4, mucin 4, cell surface associated, [Score=171, Expect=1e-41]; ENSG00000273984, MUC4, mucin 4, cell surface associated, [Score=171, Expect=1e-41]; ENSG00000273822, MUC4, mucin 4, cell surface associated, [Score=171, Expect=1e-41]; ENSG00000278303, MUC4, mucin 4, cell surface associated, [Score=171, Expect=1e-41]; ENSG00000145113, MUC4, mucin 4, cell surface associated, [Score=171, Expect=2e-41]; ENSG00000278468, MUC4, mucin 4, cell surface associated, [Score=169, Expect=7e-41]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=116, Expect=5e-25]; ENSMUSG00000063681, Crb1, crumbs family member 1, photoreceptor morphogenesis associated, [Score=115, Expect=3e-25]; ENSMUSG00000079620, Muc4, mucin 4, [Score=111, Expect=1e-23]} {Dmel: FBgn0051665, wry, weary, [Score=119, Expect=2e-26]} {Celegans: WBGene00001403, fbl-1, Fibulin-1, [Score=105, Expect=2e-22]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=95.5, Expect=4e-19]} {RNA1509_14436, RNA1509_2591} {RNA1310_1268.1, RNA1509_14436} {RNA1509_14436, RNA815_473}
39. MligTC455_40592 3968 82.67 Mlig455_003505, Mlig455_015552

Neo: -

Age: logFC(26M/2M)=-0.400

Regeneration-downregulated BL: -1.765

Regeneration-depleted BL: -1.765

0.96 - - - - 0.960 -

Mlig455_003505 {REF} {Length: 5449} {Dmel: FBgn0036520, CG13449, [RH, Score=52.8, Expect=8e-07]} {Smed: dd_Smed_v6_30766_0_1, dd_Smed_v6_30766_0_1, [RH, Score=93.2, Expect=3e-20]} {RNA1509_6586} {RNA1310_14962.1, RNA1509_6586} {RNA1509_6586, RNA815_5800}

Mlig455_015552 {REF} {Length: 3165} {Dmel: FBgn0036520, CG13449, [RH, Score=53.5, Expect=6e-07]} {Smed: dd_Smed_v6_30766_0_1, dd_Smed_v6_30766_0_1, [RH, Score=93.2, Expect=3e-20]} {RNA1509_6586} {RNA1310_14962.1} {RNA815_5800}
40. MligTC455_37654 406 8.47 Mlig455_029446, Mlig455_029466

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.381

Region-enriched R7: 2.220/0.02232

LOXL2, LOXL4 0.959 - - - - 0.959 -

Mlig455_029446 {REF} {Length: 2317} {Pfam: Lysyl oxidase [PF01186.19, score=223.2]; Scavenger receptor cysteine-rich domain [PF00530.20, score=92.2]; Scavenger receptor cysteine-rich domain [PF15494.8, score=31.8]} {Human: ENSG00000134013, LOXL2, lysyl oxidase like 2, [Score=232, Expect=1e-68]; ENSG00000138131, LOXL4, lysyl oxidase like 4, [Score=223, Expect=4e-65]} {Mouse: ENSMUSG00000034205, Loxl2, lysyl oxidase-like 2, [Score=224, Expect=7e-66]; ENSMUSG00000025185, Loxl4, lysyl oxidase-like 4, [Score=216, Expect=8e-63]; ENSMUSG00000000693, Loxl3, lysyl oxidase-like 3, [Score=213, Expect=9e-62]} {Dmel: FBgn0034660, lox2, lysyl oxidase-like 2, [Score=255, Expect=8e-80]} {Smed: dd_Smed_v6_10591_0_1, dd_Smed_v6_10591_0_1, [Score=277, Expect=6e-89]} {RNA1509_58726} {RNA1310_16786} {RNA815_6954}

Mlig455_029466 {REF} {Length: 2102} {Pfam: Lysyl oxidase [PF01186.19, score=261.1]; Scavenger receptor cysteine-rich domain [PF00530.20, score=107.2]; Scavenger receptor cysteine-rich domain [PF15494.8, score=30.3]} {Human: ENSG00000138131, LOXL4, lysyl oxidase like 4, [RH, Score=278, Expect=5e-83]; ENSG00000134013, LOXL2, lysyl oxidase like 2, [RH, Score=277, Expect=1e-82]; ENSG00000115318, LOXL3, lysyl oxidase like 3, [RH, Score=273, Expect=4e-81]} {Mouse: ENSMUSG00000000693, Loxl3, lysyl oxidase-like 3, [RH, Score=270, Expect=3e-80]; ENSMUSG00000025185, Loxl4, lysyl oxidase-like 4, [RH, Score=269, Expect=6e-80]; ENSMUSG00000034205, Loxl2, lysyl oxidase-like 2, [RH, Score=259, Expect=5e-76]} {Dmel: FBgn0034660, lox2, lysyl oxidase-like 2, [RH, Score=330, Expect=7e-106]} {Celegans: WBGene00015646, mlt-10, [Score=132, Expect=5e-32]} {Smed: dd_Smed_v6_10591_0_1, dd_Smed_v6_10591_0_1, [RH, Score=358, Expect=2e-117]} {RNA1509_58726} {RNA1310_16786} {RNA815_6954}
41. MligTC455_39507 187 3.9 Mlig455_017438, Mlig455_030968

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.995

Region-enriched R2: 3.412/0.02282

DTHD1 0.959 - - - - 0.959 -

Mlig455_017438 {REF} {Length: 3635} {Pfam: Death domain [PF00531.24, score=30.4]} {Human: ENSG00000197057, DTHD1, death domain containing 1, [Score=118, Expect=2e-26]} {Mouse: ENSMUSG00000090326, Dthd1, death domain containing 1, [RH, Score=99.8, Expect=7e-21]} {Smed: dd_Smed_v6_13807_0_1, dd_Smed_v6_13807_0_1, [RH, Score=169, Expect=4e-43]} {RNA1509_9917} {RNA1310_4320.1, RNA1509_9917} {RNA1509_9917, RNA815_4192.1}

Mlig455_030968 {REF} {Length: 944} {Human: ENSG00000197057, DTHD1, death domain containing 1, [Score=67.4, Expect=7e-12]} {Mouse: ENSMUSG00000090326, Dthd1, death domain containing 1, [Score=65.5, Expect=2e-11]} {Smed: dd_Smed_v6_13807_0_1, dd_Smed_v6_13807_0_1, [Score=87.8, Expect=3e-19]} {RNA1509_9917} {RNA1310_4320.1} {RNA815_4192.1}
42. MligTC455_30618 652 13.59 Mlig455_031172

Neo: -

Age: logFC(26M/2M)=-0.520

ITPR2 0.958 - - - - 0.958 - Mlig455_031172 {REF} {Length: 9583} {Pfam: RIH domain [PF01365.23, score=93.8]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=76.1]; MIR domain [PF02815.21, score=44.8]} {Human: ENSG00000123104, ITPR2, inositol 1,4,5-trisphosphate receptor type 2, [Score=214, Expect=5e-55]; ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=205, Expect=3e-52]} {Mouse: ENSMUSG00000042644, Itpr3, inositol 1,4,5-triphosphate receptor 3, [Score=222, Expect=2e-57]; ENSMUSG00000030287, Itpr2, inositol 1,4,5-triphosphate receptor 2, [Score=213, Expect=8e-55]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=194, Expect=3e-49]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=140, Expect=7e-33]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1298, Expect=0.0]} {RNA1509_23724, RNA1509_55174, RNA1509_5518} {RNA1310_129.1, RNA1509_23724, RNA1509_55174, RNA1509_5518} {RNA1509_23724, RNA1509_55174, RNA1509_5518, RNA815_62.1}
43. MligTC455_40057 612 12.75 Mlig455_054931

Neo: -

Age: -

FADS1 0.958 - - - - 0.958 - Mlig455_054931 {REF} {Length: 2003} {Pfam: Fatty acid desaturase [PF00487.26, score=114.0]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=63.0]} {Human: ENSG00000149485, FADS1, fatty acid desaturase 1, [Score=414, Expect=2e-141]; ENSG00000134824, FADS2, fatty acid desaturase 2, [Score=410, Expect=1e-140]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [Score=417, Expect=2e-143]; ENSMUSG00000010663, Fads1, fatty acid desaturase 1, [Score=402, Expect=1e-137]} {Dmel: FBgn0036575, CG5157, [Score=50.8, Expect=9e-08]} {Celegans: WBGene00001396, fat-4, Delta(5) fatty acid desaturase fat-4, [RH, Score=129, Expect=1e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [RH, Score=481, Expect=2e-169]} {RNA1509_36781} {RNA1310_14458, RNA1509_36781} {RNA1509_36781, RNA815_5784}
44. MligTC455_20441 7966 165.95 Mlig455_066269

Neo: -

Age: logFC(26M/2M)=-0.347

Regeneration-downregulated BL: -1.038

Regeneration-depleted BL: -1.038

TSPAN16 0.957 - - - - 0.957 - Mlig455_066269 {REF} {Length: 2526} {Pfam: Tetraspanin family [PF00335.22, score=77.2]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=49.3, Expect=2e-06]} {Mouse: ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=48.1, Expect=4e-06]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=66.6, Expect=2e-12]} {Smed: dd_Smed_v6_3175_0_1, dd_Smed_v6_3175_0_1, [RH, Score=105, Expect=2e-26]} {RNA1509_1984} {RNA1310_20011, RNA1509_1984} {RNA1509_1984, RNA815_7057.1}
45. MligTC455_49763 130 2.72 Mlig455_006404

Neo: -

Age: -

Region-enriched R2: 3.029/0.02346

KREMEN1 0.957 - - - - 0.957 - Mlig455_006404 {REF} {Length: 1879} {Pfam: WSC domain [PF01822.21, score=53.7]; PAN domain [PF00024.28, score=24.0]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=45.1, Expect=1e-05]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=44.7, Expect=1e-05]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=47.8, Expect=9e-07]} {RNA1509_53783} {RNA1310_43597} {RNA815_9084.2}
46. MligTC455_26143 3631 75.65 Mlig455_036434, Mlig455_054605

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.391

ADIPOR2 0.956 - - - - 0.956 -

Mlig455_036434 {REF} {Length: 1863} {Pfam: Haemolysin-III related [PF03006.22, score=206.7]} {Human: ENSG00000006831, ADIPOR2, adiponectin receptor 2, [Score=246, Expect=2e-79]; ENSG00000285070, ADIPOR2, adiponectin receptor 2, [Score=246, Expect=2e-79]} {Mouse: ENSMUSG00000030168, Adipor2, adiponectin receptor 2, [Score=246, Expect=3e-79]} {Dmel: FBgn0038984, AdipoR, Adiponectin receptor, [Score=249, Expect=6e-81]} {Celegans: WBGene00016610, paqr-1, Progestin and adipoQ receptor-like protein 1, [Score=233, Expect=4e-75]} {Smed: dd_Smed_v6_5202_0_1, dd_Smed_v6_5202_0_1, [Score=241, Expect=9e-78]} {RNA1509_22446} {RNA1310_23742.1, RNA1509_22446} {RNA1509_22446, RNA815_11326.1}

Mlig455_054605 {REF} {Length: 1817} {Pfam: Haemolysin-III related [PF03006.22, score=206.6]} {Human: ENSG00000006831, ADIPOR2, adiponectin receptor 2, [Score=246, Expect=3e-79]; ENSG00000285070, ADIPOR2, adiponectin receptor 2, [Score=246, Expect=3e-79]} {Mouse: ENSMUSG00000030168, Adipor2, adiponectin receptor 2, [Score=246, Expect=3e-79]} {Dmel: FBgn0038984, AdipoR, Adiponectin receptor, [Score=249, Expect=7e-81]} {Celegans: WBGene00016610, paqr-1, Progestin and adipoQ receptor-like protein 1, [Score=233, Expect=3e-75]} {Smed: dd_Smed_v6_5202_0_1, dd_Smed_v6_5202_0_1, [Score=240, Expect=2e-77]} {RNA1509_11297} {RNA1310_23742.2} {RNA815_11326.1}
47. MligTC455_39145 860 17.92 Mlig455_045710

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.035/0.04635

0.956 - - - - 0.956 - Mlig455_045710 {REF} {Length: 2657} {Pfam: Family of unknown function (DUF5580) [PF17743.3, score=80.4]} {Smed: dd_Smed_v6_9326_0_1, dd_Smed_v6_9326_0_1, [RH, Score=180, Expect=1e-49]} {RNA1509_11160, RNA1509_32698} {RNA1310_8387, RNA1509_11160, RNA1509_32698} {RNA1509_11160, RNA1509_32698, RNA815_15696.1}
48. MligTC455_30275 491 10.22 Mlig455_030075, Mlig455_036671

Neo: -

Age: -

Regeneration-upregulated BL: 3.836

Regeneration-enriched BL: 3.836

0.955 - - - - 0.955 -

Mlig455_030075 {REF} {Length: 336} {Pfam: DNA polymerase type B, organellar and viral [PF03175.15, score=18.6]} {Celegans: WBGene00022511, ZC53.4, [Score=84.3, Expect=3e-20]} {Smed: dd_Smed_v6_23154_0_1, dd_Smed_v6_23154_0_1, [Score=120, Expect=2e-34]} {RNA1509_5039} {RNA1310_3396.1} {RNA815_1342.1}

Mlig455_036671 {REF} {Length: 810} {Pfam: DNA polymerase type B, organellar and viral [PF03175.15, score=34.0]} {Celegans: WBGene00022511, ZC53.4, [Score=151, Expect=3e-41]} {Smed: dd_Smed_v6_23154_0_1, dd_Smed_v6_23154_0_1, [Score=174, Expect=5e-53]} {RNA1509_5039} {RNA1310_3396.1} {RNA815_1342.1}
49. MligTC455_31637 158 3.29 Mlig455_011919, Mlig455_011929, Mlig455_027031

Neo: -

Age: Up-Down-Up

0.954 - - - - 0.954 -

Mlig455_011919 {REF} {Length: 3794} {Pfam: MULE transposase domain [PF10551.11, score=19.8]} {RNA1509_42928} {RNA1310_22278} {RNA815_25813.1}

Mlig455_011929 {REF} {Length: 6289} {Pfam: MULE transposase domain [PF10551.11, score=19.7]} {RNA1509_32522, RNA1509_53350} {RNA1310_5450.1, RNA1509_32522} {RNA1509_32522, RNA815_7136.2}

Mlig455_027031 {REF} {Length: 1091} {Pfam: MULE transposase domain [PF10551.11, score=20.0]} {RNA1310_22278} {RNA815_36567}
50. MligTC455_34014 33 0.69 Mlig455_033785

Neo: -

Age: -

0.954 - - - - 0.954 - Mlig455_033785 {REF} {Length: 5958} {RNA1509_56561} {RNA1310_25982} {RNA815_38909}
51. MligTC455_35223 384 8 Mlig455_019066, Mlig455_064303, Mlig455_064338

Neo: -

Age: Down-Up-Up

Region-enriched R2: 2.984/0.02326

LPIN2, LPIN3 0.954 - - - - 0.954 -

Mlig455_019066 {REF} {Length: 1843} {Pfam: LNS2 (Lipin/Ned1/Smp2) [PF08235.15, score=274.9]; lipin, N-terminal conserved region [PF04571.16, score=79.9]} {Human: ENSG00000101577, LPIN2, lipin 2, [Score=240, Expect=2e-69]; ENSG00000132793, LPIN3, lipin 3, [Score=238, Expect=8e-69]} {Mouse: ENSMUSG00000024052, Lpin2, lipin 2, [Score=237, Expect=2e-68]; ENSMUSG00000027412, Lpin3, lipin 3, [Score=236, Expect=1e-68]} {Dmel: FBgn0263593, Lpin, Lipin, [Score=250, Expect=8e-73]} {Celegans: WBGene00010425, lpin-1, LiPIN (Mammalian lipodystrophy associated) homolog, [Score=226, Expect=3e-65]} {Smed: dd_Smed_v6_8002_0_1, dd_Smed_v6_8002_0_1, [Score=239, Expect=1e-70]} {RNA1509_50910} {RNA1310_14125.1} {RNA815_37382}

Mlig455_064303 {REF} {Length: 1843} {Pfam: LNS2 (Lipin/Ned1/Smp2) [PF08235.15, score=274.9]; lipin, N-terminal conserved region [PF04571.16, score=76.0]} {Human: ENSG00000101577, LPIN2, lipin 2, [Score=240, Expect=2e-69]; ENSG00000132793, LPIN3, lipin 3, [Score=238, Expect=7e-69]} {Mouse: ENSMUSG00000024052, Lpin2, lipin 2, [Score=237, Expect=2e-68]; ENSMUSG00000027412, Lpin3, lipin 3, [Score=236, Expect=2e-68]} {Dmel: FBgn0263593, Lpin, Lipin, [Score=250, Expect=7e-73]} {Celegans: WBGene00010425, lpin-1, LiPIN (Mammalian lipodystrophy associated) homolog, [Score=226, Expect=3e-65]} {Smed: dd_Smed_v6_8002_0_1, dd_Smed_v6_8002_0_1, [Score=239, Expect=1e-70]} {RNA1509_50910} {RNA1310_14125.1} {RNA815_37382}

Mlig455_064338 {REF} {Length: 1748} {Pfam: LNS2 (Lipin/Ned1/Smp2) [PF08235.15, score=275.1]; lipin, N-terminal conserved region [PF04571.16, score=78.9]} {Human: ENSG00000132793, LPIN3, lipin 3, [Score=239, Expect=2e-69]; ENSG00000101577, LPIN2, lipin 2, [Score=238, Expect=6e-69]} {Mouse: ENSMUSG00000027412, Lpin3, lipin 3, [Score=238, Expect=2e-69]; ENSMUSG00000024052, Lpin2, lipin 2, [Score=237, Expect=1e-68]} {Dmel: FBgn0263593, Lpin, Lipin, [Score=246, Expect=6e-72]} {Celegans: WBGene00010425, lpin-1, LiPIN (Mammalian lipodystrophy associated) homolog, [Score=225, Expect=2e-65]} {Smed: dd_Smed_v6_8002_0_1, dd_Smed_v6_8002_0_1, [Score=238, Expect=1e-70]} {RNA1509_50910} {RNA1310_14125.1} {RNA815_37382}
52. MligTC455_52029 1723 35.89 Mlig455_000356

Neo: -

Age: Down-Up-Up

DLL1 0.954 - - - - 0.954 - Mlig455_000356 {REF} {Length: 2514} {TRANSSPLICED} {Pfam: EGF-like domain [PF00008.29, score=87.1]; Human growth factor-like EGF [PF12661.9, score=49.5]; Delta serrate ligand [PF01414.21, score=48.8]; Calcium-binding EGF domain [PF07645.17, score=26.3]; EGF domain [PF12947.9, score=19.4]} {Human: ENSG00000275555, DLL1, delta like canonical Notch ligand 1, [Score=171, Expect=8e-45]; ENSG00000198719, DLL1, delta like canonical Notch ligand 1, [Score=171, Expect=8e-45]; ENSG00000128917, DLL4, delta like canonical Notch ligand 4, [Score=169, Expect=2e-44]; ENSG00000134376, CRB1, crumbs 1, cell polarity complex component, [Score=167, Expect=6e-43]} {Mouse: ENSMUSG00000014773, Dll1, delta like canonical Notch ligand 1, [Score=172, Expect=2e-45]; ENSMUSG00000027276, Jag1, jagged 1, [Score=167, Expect=5e-43]; ENSMUSG00000027878, Notch2, notch 2, [Score=165, Expect=3e-42]; ENSMUSG00000027314, Dll4, delta like canonical Notch ligand 4, [Score=164, Expect=1e-42]; ENSMUSG00000035403, Crb2, crumbs family member 2, [Score=164, Expect=4e-42]; ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=164, Expect=4e-42]} {Dmel: FBgn0004647, N, Notch, [Score=174, Expect=1e-45]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=137, Expect=2e-33]} {Smed: dd_Smed_v6_11876_0_1, dd_Smed_v6_11876_0_1, [Score=148, Expect=4e-37]} {RNA1509_42642, RNA1509_9673} {RNA1310_6973.1, RNA1509_42642, RNA1509_9673} {RNA1509_42642, RNA1509_9673, RNA815_2635.1}
53. MligTC455_20442 14887 310.15 Mlig455_023972, Mlig455_066251

Neo: -

Age: Down-Up-Up

TSPAN16 0.953 - - - - 0.953 -

Mlig455_023972 {REF} {Length: 2924} {Pfam: Tetraspanin family [PF00335.22, score=77.6]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=49.3, Expect=2e-06]} {Mouse: ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=48.1, Expect=4e-06]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=67.0, Expect=1e-12]} {Smed: dd_Smed_v6_3175_0_1, dd_Smed_v6_3175_0_1, [RH, Score=105, Expect=2e-26]} {RNA1509_1984} {RNA1310_20011} {RNA815_7057.1}

Mlig455_066251 {REF} {Length: 2553} {Pfam: Tetraspanin family [PF00335.22, score=77.6]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=49.3, Expect=2e-06]} {Mouse: ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=48.1, Expect=4e-06]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=67.0, Expect=1e-12]} {Smed: dd_Smed_v6_3175_0_1, dd_Smed_v6_3175_0_1, [RH, Score=105, Expect=2e-26]} {RNA1509_18769, RNA1509_1984, RNA1509_20386} {RNA1310_20011, RNA1509_18769, RNA1509_20386} {RNA1509_18769, RNA1509_20386, RNA815_7057.1}
54. MligTC455_29048 529 11.01 Mlig455_024096

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.420

Region-enriched R2: 1.997/0.00679

WDR49 0.953 - - - - 0.953 - Mlig455_024096 {REF} {Length: 4603} {Pfam: WD domain, G-beta repeat [PF00400.34, score=72.6]; EF-hand domain pair [PF13833.8, score=25.0]; EF-hand domain pair [PF13499.8, score=20.8]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=19.2]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [RH, Score=754, Expect=0.0]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [RH, Score=471, Expect=1e-151]} {Dmel: FBgn0267449, WDY, WD40 Y, [Score=142, Expect=4e-34]} {Smed: dd_Smed_v6_13248_0_6, dd_Smed_v6_13248_0_6, [RH, Score=932, Expect=0.0]} {RNA1509_12036} {RNA1310_8128.1} {RNA815_8389.1}
55. MligTC455_18569 79 1.65 Mlig455_002173, Mlig455_002274, Mlig455_002318

Neo: -

Age: -

Region-enriched R4: 6.510/0.00058

0.952 - - - - 0.952 -

Mlig455_002173 {REF} {Length: 1129} {NoTransDecoderORF} {RNA1509_52353} {RNA1310_130608} {RNA815_60304}

Mlig455_002274 {REF} {Length: 1130} {NoTransDecoderORF} {RNA1509_52353} {RNA1310_130608} {RNA815_60304}

Mlig455_002318 {REF} {Length: 1012} {NoTransDecoderORF} {RNA1509_52353} {RNA1310_130608} {RNA815_60304}
56. MligTC455_19275 407 8.47 Mlig455_037548

Neo: -

Age: logFC(26M/2M)=0.488

Region-enriched R2: 3.247/0.04164

CHRNA10 0.952 - - - - 0.952 - Mlig455_037548 {REF} {Length: 959} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=87.9]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=96.7, Expect=1e-22]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=97.1, Expect=7e-23]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=95.1, Expect=5e-22]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=110, Expect=1e-27]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=119, Expect=8e-31]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=93.2, Expect=1e-21]} {RNA1509_23115} {RNA1310_34970} {RNA815_15305.1}
57. MligTC455_20440 7716 160.76 Mlig455_034502

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.410

TSPAN16 0.952 - - - - 0.952 - Mlig455_034502 {REF} {Length: 1176} {Pfam: Tetraspanin family [PF00335.22, score=77.6]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=49.3, Expect=2e-06]} {Mouse: ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=48.1, Expect=4e-06]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=67.0, Expect=1e-12]} {Smed: dd_Smed_v6_3175_0_1, dd_Smed_v6_3175_0_1, [RH, Score=105, Expect=2e-26]} {RNA1509_1984, RNA1509_52808} {RNA1310_20011, RNA1509_52808} {RNA1509_52808, RNA815_7057.1}
58. MligTC455_43528 1273 26.52 Mlig455_068411

Neo: -

Age: Down-Up-Up

0.952 - - - - 0.952 - Mlig455_068411 {REF} {Length: 842} {Pfam: Pancreatic hormone peptide [PF00159.20, score=37.0]} {RNA1509_15391, RNA1509_36078, RNA1509_47628} {RNA1310_43859, RNA1509_15391, RNA1509_36078, RNA1509_47628} {RNA1509_15391, RNA1509_36078, RNA1509_47628, RNA815_26881}
59. MligTC455_18720 595 12.4 Mlig455_041810

Neo: -

Age: logFC(26M/2M)=-0.320

ANKUB1 0.951 - - - - 0.951 - Mlig455_041810 {REF} {Length: 2454} {Pfam: Ubiquitin family [PF00240.25, score=36.0]} {Human: ENSG00000206199, ANKUB1, ankyrin repeat and ubiquitin domain containing 1, [RH, Score=258, Expect=8e-78]} {Mouse: ENSMUSG00000074591, Ankub1, ankrin repeat and ubiquitin domain containing 1, [RH, Score=258, Expect=5e-78]} {Smed: dd_Smed_v6_9027_0_1, dd_Smed_v6_9027_0_1, [RH, Score=508, Expect=2e-173]} {RNA1509_23349, RNA1509_30870, RNA1509_7686} {RNA1310_10366.1, RNA1509_23349, RNA1509_30870, RNA1509_7686} {RNA1509_23349, RNA1509_30870, RNA1509_7686, RNA815_3711.1}
60. MligTC455_19278 4335 90.31 Mlig455_057304, Mlig455_070944

Neo: -

Age: logFC(26M/2M)=0.686

Region-specific R2: 5.590

Region-enriched R2: 5.465/0.00000
Region-enriched R3: 2.308/0.00629

CHRNA10 0.951 - - - - 0.951 -

Mlig455_057304 {REF} {Length: 1001} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=71.6]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=77.0, Expect=2e-16]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=75.9, Expect=4e-16]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=75.5, Expect=6e-16]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=73.9, Expect=2e-15]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=93.6, Expect=2e-22]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=100, Expect=5e-25]} {Smed: dd_Smed_v6_11955_0_1, dd_Smed_v6_11955_0_1, [Score=82.8, Expect=8e-19]} {RNA1509_23115} {RNA1310_34970} {RNA815_15305.1}

Mlig455_070944 {REF} {Length: 1060} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=88.2]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=95.9, Expect=6e-22]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=96.3, Expect=3e-22]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=94.7, Expect=1e-21]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=112, Expect=7e-28]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=118, Expect=4e-30]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=98.6, Expect=2e-23]} {RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1310_34970, RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1509_23115, RNA1509_43907, RNA1509_9432, RNA815_15305.1}
61. MligTC455_19847 287 5.99 Mlig455_018312

Neo: -

Age: Down-Up-Down

0.951 - - - - 0.951 - Mlig455_018312 {REF} {Length: 1351} {Pfam: Phosphotyrosine interaction domain (PTB/PID) [PF14719.8, score=27.9]; Phosphotyrosine interaction domain (PTB/PID) [PF00640.25, score=27.7]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.9]} {Dmel: FBgn0035431, CG14968, [Score=75.9, Expect=4e-16]} {Smed: dd_Smed_v6_16269_0_1, dd_Smed_v6_16269_0_1, [Score=46.6, Expect=6e-06]} {RNA1509_28129} {RNA1310_26006} {RNA815_14793}
62. MligTC455_43906 878 18.29 Mlig455_044333, Mlig455_044345

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.277

RAI14 0.951 - - - - 0.951 -

Mlig455_044333 {REF} {Length: 5825} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=81.1]; Ankyrin repeat [PF00023.32, score=72.8]; Ankyrin repeats (many copies) [PF13637.8, score=63.6]; Ankyrin repeat [PF13606.8, score=48.5]; Ankyrin repeats (many copies) [PF13857.8, score=44.2]} {Human: ENSG00000039560, RAI14, retinoic acid induced 14, [Score=90.1, Expect=3e-17]} {Mouse: ENSMUSG00000022246, Rai14, retinoic acid induced 14, [Score=94.4, Expect=9e-19]; ENSMUSG00000007827, Ankrd26, ankyrin repeat domain 26, [Score=89.7, Expect=3e-17]} {Dmel: FBgn0039590, CG10011, [Score=82.4, Expect=4e-15]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=85.9, Expect=3e-16]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [Score=73.9, Expect=7e-13]} {RNA1509_7603} {RNA1310_960.3} {RNA815_5173}

Mlig455_044345 {REF} {Length: 6035} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=87.7]; Ankyrin repeat [PF00023.32, score=72.9]; Ankyrin repeats (many copies) [PF13637.8, score=66.8]; Ankyrin repeats (many copies) [PF13857.8, score=50.5]; Ankyrin repeat [PF13606.8, score=50.0]} {Human: ENSG00000039560, RAI14, retinoic acid induced 14, [Score=94.7, Expect=9e-19]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=92.0, Expect=6e-19]} {Mouse: ENSMUSG00000022246, Rai14, retinoic acid induced 14, [Score=99.4, Expect=3e-20]} {Dmel: FBgn0039590, CG10011, [Score=87.4, Expect=1e-16]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=86.3, Expect=2e-16]} {Smed: dd_Smed_v6_7952_0_2, dd_Smed_v6_7952_0_2, [Score=80.5, Expect=8e-15]} {RNA1509_7603} {RNA1310_960.3} {RNA815_5173}
63. MligTC455_14236 149 3.1 Mlig455_017105

Neo: -

Age: Up-Down-Down

WDSUB1 0.95 - - - - 0.950 - Mlig455_017105 {REF} {Length: 3758} {Pfam: WD domain, G-beta repeat [PF00400.34, score=166.2]; U-box domain [PF04564.17, score=59.8]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=48.5]; SAM domain (Sterile alpha motif) [PF07647.19, score=44.6]; SAM domain (Sterile alpha motif) [PF00536.32, score=42.6]; WD40 region of Ge1, enhancer of mRNA-decapping protein [PF16529.7, score=28.6]} {Human: ENSG00000196151, WDSUB1, WD repeat, sterile alpha motif and U-box domain containing 1, [Score=210, Expect=2e-60]} {Mouse: ENSMUSG00000026988, Wdsub1, WD repeat, SAM and U-box domain containing 1, [Score=197, Expect=2e-56]} {Dmel: FBgn0021874, Nle, Notchless, [Score=105, Expect=9e-24]} {Celegans: WBGene00003047, lis-1, Lissencephaly-1 homolog, [Score=99.0, Expect=5e-22]} {Smed: dd_Smed_v6_5139_0_1, dd_Smed_v6_5139_0_1, [Score=103, Expect=2e-24]} {RNA1310_51636} {RNA815_18559}
64. MligTC455_19266 1038 21.61 Mlig455_004528, Mlig455_028530

Neo: -

Age: -

Region-specific R2: 2.706

Region-enriched R2: 1.766/0.00005

NCALD 0.95 - - - - 0.950 -

Mlig455_004528 {REF} {Length: 3958} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_14564} {RNA1310_18405, RNA1509_14564} {RNA1509_14564, RNA815_10180.1}

Mlig455_028530 {REF} {Length: 3453} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_13995, RNA1509_14564, RNA1509_30926} {RNA1310_18405, RNA1509_13995, RNA1509_30926} {RNA1509_13995, RNA1509_30926, RNA815_10180.1}
65. MligTC455_25268 55 1.15 Mlig455_000562, Mlig455_030361

Neo: -

Age: -

Region-enriched R2: 7.728/0.00671

0.95 - - - - 0.950 -

Mlig455_000562 {REF} {Length: 844} {Pfam: DNA gyrase inhibitor YacG [PF03884.16, score=19.0]} {RNA1310_51946} {RNA815_48498}

Mlig455_030361 {REF} {Length: 1237} {Pfam: DNA gyrase inhibitor YacG [PF03884.16, score=18.5]} {RNA1509_24858} {RNA1310_51946} {RNA815_48498}
66. MligTC455_28074 91 1.89 Mlig455_042655, Mlig455_047014

Neo: -

Age: -

0.95 - - - - 0.950 -

Mlig455_042655 {REF} {Length: 956} {NoTransDecoderORF} {RNA1509_27021} {RNA1310_14467} {RNA815_5428.1}

Mlig455_047014 {REF} {Length: 5125} {RNA1509_31395} {RNA1310_10847.1} {RNA815_5428.1}
67. MligTC455_44300 1386 28.88 Mlig455_000467

Neo: -

Age: -

Region-enriched R2: 1.856/0.03510

0.95 - - - - 0.950 - Mlig455_000467 {REF} {Length: 459} {NoTransDecoderORF} {RNA1509_16536} {RNA1310_30744} {RNA815_13864}

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