Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_32700 | 535 | 11.16 | Mlig455_038216, Mlig455_038291 | Neo: Irradiation Age: Up-Down-Down |
FGFR3 | Mlig455_038216 {REF} {Length: 5847} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=270.7]; Protein kinase domain [PF00069.27, score=129.9]; Immunoglobulin domain [PF13927.8, score=37.1]; Immunoglobulin domain [PF00047.27, score=33.1]; Immunoglobulin domain [PF13895.8, score=29.4]; Immunoglobulin V-set domain [PF07686.19, score=25.2]; Fungal protein kinase [PF17667.3, score=18.7]} {Human: ENSG00000068078, FGFR3, fibroblast growth factor receptor 3, [RH, Score=224, Expect=6e-62]; ENSG00000077782, FGFR1, fibroblast growth factor receptor 1, [RH, Score=220, Expect=3e-60]; ENSG00000066468, FGFR2, fibroblast growth factor receptor 2, [RH, Score=214, Expect=3e-58]} {Mouse: ENSMUSG00000031565, Fgfr1, fibroblast growth factor receptor 1, [RH, Score=220, Expect=2e-60]; ENSMUSG00000054252, Fgfr3, fibroblast growth factor receptor 3, [RH, Score=219, Expect=7e-60]; ENSMUSG00000030849, Fgfr2, fibroblast growth factor receptor 2, [RH, Score=214, Expect=4e-59]} {Dmel: FBgn0010389, htl, heartless, [RH, Score=223, Expect=2e-61]} {Celegans: WBGene00001184, egl-15, Myoblast growth factor receptor egl-15, [RH, Score=223, Expect=2e-60]} {Smed: dd_Smed_v6_12998_0_1, dd_Smed_v6_12998_0_1, [RH, Score=223, Expect=3e-61]} {RNA1509_25243} {RNA1310_14119} {RNA815_2456.1} Mlig455_038291 {REF} {Length: 4686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=270.7]; Protein kinase domain [PF00069.27, score=128.7]; Immunoglobulin domain [PF13927.8, score=34.4]; Immunoglobulin domain [PF00047.27, score=30.3]; Immunoglobulin domain [PF13895.8, score=27.9]; Immunoglobulin V-set domain [PF07686.19, score=23.2]; Fungal protein kinase [PF17667.3, score=18.7]} {Human: ENSG00000068078, FGFR3, fibroblast growth factor receptor 3, [RH, Score=221, Expect=8e-61]; ENSG00000077782, FGFR1, fibroblast growth factor receptor 1, [RH, Score=217, Expect=4e-59]; ENSG00000066468, FGFR2, fibroblast growth factor receptor 2, [RH, Score=211, Expect=4e-57]} {Mouse: ENSMUSG00000054252, Fgfr3, fibroblast growth factor receptor 3, [RH, Score=217, Expect=5e-59]; ENSMUSG00000031565, Fgfr1, fibroblast growth factor receptor 1, [RH, Score=217, Expect=2e-59]; ENSMUSG00000030849, Fgfr2, fibroblast growth factor receptor 2, [RH, Score=211, Expect=5e-58]} {Dmel: FBgn0285896, btl, breathless, [RH, Score=221, Expect=2e-59]} {Celegans: WBGene00001184, egl-15, Myoblast growth factor receptor egl-15, [RH, Score=221, Expect=1e-59]} {Smed: dd_Smed_v6_12998_0_1, dd_Smed_v6_12998_0_1, [RH, Score=220, Expect=3e-60]} {RNA1509_25243} {RNA1310_14119} {RNA815_2456.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 2.492 | 3.743 | 0.05030 | 0.52994 | |
RegionR2 | -0.994 | 3.743 | 0.16273 | 0.50494 | |
RegionR3 | -1.911 | 3.743 | 0.00325 | 0.07103 | |
RegionR4 | -0.31 | 3.743 | 0.67957 | 0.97416 | |
RegionR5 | 0.511 | 3.743 | 0.26587 | 0.58900 | |
RegionR6 | -0.843 | 3.743 | 0.11958 | 0.63065 | |
RegionR7 | 0.554 | 3.743 | 0.38130 | 1.00000 | |
RegionR8 | 0.502 | 3.743 | 0.50515 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -8.246 | 3.743 | 0.03448 | 0.64695 | |
RegenerationR2 | -1.022 | 3.743 | 0.12838 | 0.55267 | |
RegenerationR3 | 0.646 | 3.743 | 0.39132 | 0.79688 | |
RegenerationR4 | -0.583 | 3.743 | 0.41230 | 0.82207 | |
RegenerationR5 | -0.708 | 3.743 | 0.26465 | 0.69616 | |
RegenerationR6 | 1.443 | 3.743 | 0.02960 | 0.21471 | |
RegenerationBL | 1.73 | 3.743 | 0.00918 | 0.09568 | |
RegenerationTP | -0.998 | 3.743 | 0.20292 | 0.64433 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_32700 | 535 | 11.16 | Mlig455_038216, Mlig455_038291 | Neo: Irradiation Age: Up-Down-Down |
FGFR3 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_038216 {REF} {Length: 5847} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=270.7]; Protein kinase domain [PF00069.27, score=129.9]; Immunoglobulin domain [PF13927.8, score=37.1]; Immunoglobulin domain [PF00047.27, score=33.1]; Immunoglobulin domain [PF13895.8, score=29.4]; Immunoglobulin V-set domain [PF07686.19, score=25.2]; Fungal protein kinase [PF17667.3, score=18.7]} {Human: ENSG00000068078, FGFR3, fibroblast growth factor receptor 3, [RH, Score=224, Expect=6e-62]; ENSG00000077782, FGFR1, fibroblast growth factor receptor 1, [RH, Score=220, Expect=3e-60]; ENSG00000066468, FGFR2, fibroblast growth factor receptor 2, [RH, Score=214, Expect=3e-58]} {Mouse: ENSMUSG00000031565, Fgfr1, fibroblast growth factor receptor 1, [RH, Score=220, Expect=2e-60]; ENSMUSG00000054252, Fgfr3, fibroblast growth factor receptor 3, [RH, Score=219, Expect=7e-60]; ENSMUSG00000030849, Fgfr2, fibroblast growth factor receptor 2, [RH, Score=214, Expect=4e-59]} {Dmel: FBgn0010389, htl, heartless, [RH, Score=223, Expect=2e-61]} {Celegans: WBGene00001184, egl-15, Myoblast growth factor receptor egl-15, [RH, Score=223, Expect=2e-60]} {Smed: dd_Smed_v6_12998_0_1, dd_Smed_v6_12998_0_1, [RH, Score=223, Expect=3e-61]} {RNA1509_25243} {RNA1310_14119} {RNA815_2456.1} Mlig455_038291 {REF} {Length: 4686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=270.7]; Protein kinase domain [PF00069.27, score=128.7]; Immunoglobulin domain [PF13927.8, score=34.4]; Immunoglobulin domain [PF00047.27, score=30.3]; Immunoglobulin domain [PF13895.8, score=27.9]; Immunoglobulin V-set domain [PF07686.19, score=23.2]; Fungal protein kinase [PF17667.3, score=18.7]} {Human: ENSG00000068078, FGFR3, fibroblast growth factor receptor 3, [RH, Score=221, Expect=8e-61]; ENSG00000077782, FGFR1, fibroblast growth factor receptor 1, [RH, Score=217, Expect=4e-59]; ENSG00000066468, FGFR2, fibroblast growth factor receptor 2, [RH, Score=211, Expect=4e-57]} {Mouse: ENSMUSG00000054252, Fgfr3, fibroblast growth factor receptor 3, [RH, Score=217, Expect=5e-59]; ENSMUSG00000031565, Fgfr1, fibroblast growth factor receptor 1, [RH, Score=217, Expect=2e-59]; ENSMUSG00000030849, Fgfr2, fibroblast growth factor receptor 2, [RH, Score=211, Expect=5e-58]} {Dmel: FBgn0285896, btl, breathless, [RH, Score=221, Expect=2e-59]} {Celegans: WBGene00001184, egl-15, Myoblast growth factor receptor egl-15, [RH, Score=221, Expect=1e-59]} {Smed: dd_Smed_v6_12998_0_1, dd_Smed_v6_12998_0_1, [RH, Score=220, Expect=3e-60]} {RNA1509_25243} {RNA1310_14119} {RNA815_2456.1} |
2. | MligTC455_23457 | 314 | 6.54 | Mlig455_029520 | Neo: - Age: Up-Down-Up Region-enriched R7: 5.927/0.00000 Regeneration-upregulated BL: 4.346 Regeneration-enriched BL: 4.346 |
FZD10 | 2.677 | - | - | - | 0.883 | 0.842 | 0.952 | Mlig455_029520 {REF} {Length: 3781} {TRANSSPLICED} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=272.7]; Fz domain [PF01392.24, score=63.7]} {Human: ENSG00000111432, FZD10, frizzled class receptor 10, [Score=275, Expect=7e-83]} {Mouse: ENSMUSG00000081683, Fzd10, frizzled class receptor 10, [Score=273, Expect=4e-82]; ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [Score=267, Expect=2e-80]; ENSMUSG00000049551, Fzd9, frizzled class receptor 9, [Score=264, Expect=7e-79]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=198, Expect=4e-54]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=210, Expect=3e-59]} {Smed: dd_Smed_v6_11650_0_1, dd_Smed_v6_11650_0_1, [Score=259, Expect=1e-76]} {RNA1310_57348} {RNA815_40236} |
3. | MligTC455_12536 | 196 | 4.09 | Mlig455_044362 | Neo: - Age: - |
2.634 | - | - | - | 0.965 | 0.903 | 0.766 | Mlig455_044362 {REF} {Length: 1085} {RNA1310_39047} {RNA815_18168} | |
4. | MligTC455_20081 | 395 | 8.24 | Mlig455_030428 | Neo: - Age: Down-Down-Up |
YEATS4 | 1.743 | - | - | - | - | 0.951 | 0.792 | Mlig455_030428 {REF} {Length: 1502} {TRANSSPLICED} {Pfam: YEATS family [PF03366.18, score=105.9]} {Human: ENSG00000127337, YEATS4, YEATS domain containing 4, [RH, Score=195, Expect=2e-62]} {Mouse: ENSMUSG00000020171, Yeats4, YEATS domain containing 4, [RH, Score=195, Expect=1e-62]} {Dmel: FBgn0031873, Gas41, [RH, Score=191, Expect=4e-61]} {Celegans: WBGene00001585, gfl-1, GAS41-Like, [RH, Score=178, Expect=3e-56]} {Smed: dd_Smed_v6_6828_0_1, dd_Smed_v6_6828_0_1, [RH, Score=186, Expect=4e-59]} {RNA1509_24299, RNA1509_34783} {RNA1310_24422, RNA1509_24299} {RNA1509_24299, RNA815_21390} |
5. | MligTC455_31606 | 113 | 2.36 | Mlig455_019067, Mlig455_064336 | Neo: Int S/G2/M Age: Up-Down-Down |
ATR | 0.974 | - | - | - | - | - | 0.974 | Mlig455_019067 {REF} {Length: 4939} {Pfam: Phosphatidylinositol 3- and 4-kinase [PF00454.29, score=186.2]; FAT domain [PF02259.25, score=68.0]; FATC domain [PF02260.22, score=42.8]} {Human: ENSG00000175054, ATR, ATR serine/threonine kinase, [RH, Score=638, Expect=0.0]} {Mouse: ENSMUSG00000032409, Atr, ataxia telangiectasia and Rad3 related, [RH, Score=649, Expect=0.0]} {Dmel: FBgn0004367, mei-41, meiotic 41, [RH, Score=476, Expect=4e-140]} {Celegans: WBGene00000226, atl-1, Serine/threonine-protein kinase ATR, [RH, Score=226, Expect=4e-60]} {Smed: dd_Smed_v6_8754_0_1, dd_Smed_v6_8754_0_1, [RH, Score=528, Expect=1e-159]} {RNA1509_16317} {RNA1310_16516} Mlig455_064336 {REF} {Length: 5998} {Pfam: Phosphatidylinositol 3- and 4-kinase [PF00454.29, score=186.3]; FAT domain [PF02259.25, score=67.2]; FATC domain [PF02260.22, score=42.7]} {Human: ENSG00000175054, ATR, ATR serine/threonine kinase, [Score=589, Expect=1e-176]} {Mouse: ENSMUSG00000032409, Atr, ataxia telangiectasia and Rad3 related, [Score=597, Expect=1e-179]} {Dmel: FBgn0004367, mei-41, meiotic 41, [RH, Score=469, Expect=3e-136]} {Celegans: WBGene00000226, atl-1, Serine/threonine-protein kinase ATR, [RH, Score=223, Expect=3e-58]} {Smed: dd_Smed_v6_8754_0_1, dd_Smed_v6_8754_0_1, [RH, Score=473, Expect=4e-139]} {RNA1509_16317} {RNA1310_16516} |
6. | MligTC455_32064 | 1866 | 38.88 | Mlig455_057655 | Neo: - Age: - Region-enriched R6: 1.464/0.00127 |
0.971 | - | - | - | - | 0.971 | - | Mlig455_057655 {REF} {Length: 2777} {Celegans: WBGene00001365, exc-4, Chloride intracellular channel exc-4, [Score=46.2, Expect=5e-07]} {Smed: dd_Smed_v6_2382_0_1, dd_Smed_v6_2382_0_1, [Score=56.6, Expect=8e-11]} {RNA1509_14679, RNA1509_53399} {RNA1310_16923, RNA1509_53399} {RNA1509_53399, RNA815_7555} | |
7. | MligTC455_41263 | 96 | 1.99 | Mlig455_009993 | Neo: - Age: - |
BCR | 0.97 | - | - | - | - | - | 0.970 | Mlig455_009993 {REF} {Length: 3188} {Pfam: RhoGAP domain [PF00620.29, score=87.3]} {Human: ENSG00000186716, BCR, BCR, RhoGEF and GTPase activating protein, [Score=84.7, Expect=3e-19]; ENSG00000276016, ABR, ABR, RhoGEF and GTPase activating protein, [Score=82.8, Expect=1e-18]; ENSG00000278741, ABR, ABR, RhoGEF and GTPase activating protein, [Score=82.8, Expect=1e-18]; ENSG00000159842, ABR, ABR, RhoGEF and GTPase activating protein, [Score=82.8, Expect=1e-18]} {Mouse: ENSMUSG00000009681, Bcr, breakpoint cluster region, [Score=85.5, Expect=1e-19]; ENSMUSG00000017631, Abr, active BCR-related gene, [Score=82.8, Expect=9e-19]} {Dmel: FBgn0025836, RhoGAP1A, Rho GTPase activating protein at 1A, [Score=80.9, Expect=3e-18]} {Celegans: WBGene00009800, rrc-1, GTPase-activating protein rrc-1, [Score=73.6, Expect=9e-16]} {Smed: dd_Smed_v6_11121_0_1, dd_Smed_v6_11121_0_1, [Score=74.3, Expect=4e-16]} {RNA1509_36484} {RNA1310_27150.1} {RNA815_24756.1} |
8. | MligTC455_27745 | 1955 | 40.73 | Mlig455_000606, Mlig455_030318, Mlig455_034135 | Neo: - |
0.969 | - | - | - | - | 0.969 | - | Mlig455_000606 {REF} {Length: 2924} {Pfam: Leucine Rich Repeat [PF00560.35, score=20.3]} {RNA1509_34433, RNA1509_47684} {RNA1310_6918, RNA1509_34433, RNA1509_47684} {RNA1509_34433, RNA1509_47684, RNA815_6936.1} Mlig455_030318 {REF} {Length: 3220} {RNA1509_34433} {RNA1310_6918} {RNA815_6936.1} Mlig455_034135 {REF} {Length: 4072} {Pfam: Leucine Rich Repeat [PF00560.35, score=20.7]} {RNA1509_15985} {RNA1310_7023} {RNA815_6936.1} |
|
9. | MligTC455_41398 | 105 | 2.19 | Mlig455_059987 | Neo: - Age: - |
0.96 | - | - | - | - | - | 0.960 | Mlig455_059987 {REF} {Length: 5243} {RNA1509_22803} {RNA1310_4729.2} {RNA815_1614} | |
10. | MligTC455_22375 | 192 | 3.99 | Mlig455_043243 | Neo: - Age: - |
0.955 | - | - | - | - | - | 0.955 | Mlig455_043243 {REF} {Length: 1433} {RNA1509_59906} {RNA1310_29774.1} {RNA815_14384.1} | |
11. | MligTC455_41147 | 2671 | 55.65 | Mlig455_031647 | Neo: Neoblast Age: - Regeneration-enriched BL: 1.690 |
HNRNPL | 0.954 | - | - | - | - | 0.954 | - | Mlig455_031647 {REF} {Length: 3303} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=111.4]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=78.4]; Occluded RNA-recognition motif [PF16842.7, score=39.0]; RRM-like domain [PF11835.10, score=26.0]} {Human: ENSG00000282947, HNRNPL, heterogeneous nuclear ribonucleoprotein L, [Score=206, Expect=5e-59]; ENSG00000104824, HNRNPL, heterogeneous nuclear ribonucleoprotein L, [Score=206, Expect=5e-59]} {Mouse: ENSMUSG00000015165, Hnrnpl, heterogeneous nuclear ribonucleoprotein L, [Score=204, Expect=1e-57]} {Dmel: FBgn0003435, sm, smooth, [Score=182, Expect=1e-50]} {Celegans: WBGene00016624, C44B7.2, [Score=157, Expect=2e-41]} {Smed: dd_Smed_v6_1327_0_1, dd_Smed_v6_1327_0_1, [Score=128, Expect=1e-31]} {RNA1509_14865, RNA1509_15213, RNA1509_3354, RNA1509_50536, RNA1509_7103} {RNA1310_5751.1, RNA1509_14865, RNA1509_15213, RNA1509_3354, RNA1509_50536, RNA1509_7103} {RNA1509_14865, RNA1509_15213, RNA1509_3354, RNA1509_50536, RNA1509_7103, RNA815_5809} |
12. | MligTC455_25860 | 1063 | 22.16 | Mlig455_005876 | Neo: - Age: - Region-enriched R6: 2.187/0.00132 |
GLIPR2 | 0.952 | - | - | - | - | 0.952 | - | Mlig455_005876 {REF} {Length: 1599} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=84.1]} {Human: ENSG00000122694, GLIPR2, GLI pathogenesis related 2, [Score=106, Expect=1e-26]} {Mouse: ENSMUSG00000028480, Glipr2, GLI pathogenesis-related 2, [Score=108, Expect=8e-28]} {Dmel: FBgn0051482, CG31482, [RH, Score=101, Expect=1e-24]} {Celegans: WBGene00017055, D2062.1, [Score=73.6, Expect=6e-15]} {Smed: dd_Smed_v6_762_0_2, dd_Smed_v6_762_0_2, [RH, Score=147, Expect=5e-41]} {RNA1509_5334} {RNA1310_33115} {RNA815_15217.1} |
13. | MligTC455_51572 | 930 | 19.38 | Mlig455_042407, Mlig455_042419 | Neo: Irradiation Age: logFC(26M/2M)=0.194 Region-enriched R5: 1.067/0.01680 |
SMAD2 | 0.951 | - | - | - | 0.951 | - | - | Mlig455_042407 {REF} {Length: 3675} {TRANSSPLICED} {Pfam: MH2 domain [PF03166.16, score=213.5]; MH1 domain [PF03165.18, score=75.5]} {Human: ENSG00000175387, SMAD2, SMAD family member 2, [Score=352, Expect=6e-118]; ENSG00000166949, SMAD3, SMAD family member 3, [Score=348, Expect=2e-116]; ENSG00000170365, SMAD1, SMAD family member 1, [Score=335, Expect=7e-111]} {Mouse: ENSMUSG00000024563, Smad2, SMAD family member 2, [Score=352, Expect=4e-118]; ENSMUSG00000032402, Smad3, SMAD family member 3, [Score=348, Expect=1e-116]; ENSMUSG00000031681, Smad1, SMAD family member 1, [Score=338, Expect=3e-112]; ENSMUSG00000027796, Smad9, SMAD family member 9, [Score=335, Expect=1e-111]} {Dmel: FBgn0011648, Mad, Mothers against dpp, [Score=333, Expect=9e-111]} {Celegans: WBGene00004856, sma-2, Dwarfin sma-2, [Score=234, Expect=8e-73]} {Smed: dd_Smed_v6_6877_0_1, dd_Smed_v6_6877_0_1, [Score=335, Expect=1e-111]} {RNA1509_14402} {RNA1310_10219} {RNA815_6467} Mlig455_042419 {REF} {Length: 6610} {Pfam: MH2 domain [PF03166.16, score=213.4]; MH1 domain [PF03165.18, score=75.4]} {Human: ENSG00000175387, SMAD2, SMAD family member 2, [Score=350, Expect=5e-117]; ENSG00000166949, SMAD3, SMAD family member 3, [Score=347, Expect=7e-116]; ENSG00000170365, SMAD1, SMAD family member 1, [Score=334, Expect=2e-110]} {Mouse: ENSMUSG00000024563, Smad2, SMAD family member 2, [Score=350, Expect=4e-117]; ENSMUSG00000032402, Smad3, SMAD family member 3, [Score=347, Expect=5e-116]; ENSMUSG00000031681, Smad1, SMAD family member 1, [Score=337, Expect=9e-112]; ENSMUSG00000027796, Smad9, SMAD family member 9, [Score=334, Expect=6e-111]} {Dmel: FBgn0011648, Mad, Mothers against dpp, [Score=333, Expect=3e-110]} {Celegans: WBGene00004856, sma-2, Dwarfin sma-2, [Score=233, Expect=3e-72]} {Smed: dd_Smed_v6_6877_0_1, dd_Smed_v6_6877_0_1, [Score=334, Expect=4e-111]} {RNA1509_14402, RNA1509_29835, RNA1509_53933, RNA1509_58625} {RNA1310_10219, RNA1509_14402, RNA1509_29835, RNA1509_53933, RNA1509_58625} {RNA1509_14402, RNA1509_29835, RNA1509_53933, RNA1509_58625, RNA815_6467} |
14. | MligTC455_52092 | 37 | 0.76 | Mlig455_025474 | Neo: - Age: - |
0.95 | - | - | - | - | - | 0.950 | Mlig455_025474 {REF} {Length: 901} {Pfam: Pancreatic hormone peptide [PF00159.20, score=19.5]} {RNA1509_56567} {RNA1310_46347} {RNA815_35686} |