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Results for MligTC455_35222

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_35222 1565 32.60 Mlig455_017065, Mlig455_069841

Neo: Irradiation

Age: logFC(26M/2M)=0.410

Region-enriched R5: 1.068/0.00328

NPC1

Mlig455_017065 {REF} {Length: 5970} {TRANSSPLICED} {Pfam: Patched family [PF02460.20, score=253.6]; Sterol-sensing domain of SREBP cleavage-activation [PF12349.10, score=182.9]; Niemann-Pick C1 N terminus [PF16414.7, score=175.1]; MMPL family [PF03176.17, score=19.4]} {Human: ENSG00000141458, NPC1, NPC intracellular cholesterol transporter 1, [Score=824, Expect=0.0]} {Mouse: ENSMUSG00000024413, Npc1, NPC intracellular cholesterol transporter 1, [Score=845, Expect=0.0]} {Dmel: FBgn0024320, Npc1a, Niemann-Pick type C-1a, [Score=796, Expect=0.0]} {Celegans: WBGene00003561, ncr-1, Niemann-Pick C1 protein homolog 1, [Score=393, Expect=3e-114]} {Smed: dd_Smed_v6_5175_0_1, dd_Smed_v6_5175_0_1, [Score=838, Expect=0.0]} {RNA1509_2118} {RNA1310_649.1} {RNA815_1096.1}

Mlig455_069841 {REF} {Length: 6003} {TRANSSPLICED} {Pfam: Patched family [PF02460.20, score=252.9]; Sterol-sensing domain of SREBP cleavage-activation [PF12349.10, score=182.7]; Niemann-Pick C1 N terminus [PF16414.7, score=175.1]; MMPL family [PF03176.17, score=19.4]} {Human: ENSG00000141458, NPC1, NPC intracellular cholesterol transporter 1, [Score=825, Expect=0.0]} {Mouse: ENSMUSG00000024413, Npc1, NPC intracellular cholesterol transporter 1, [Score=846, Expect=0.0]} {Dmel: FBgn0024320, Npc1a, Niemann-Pick type C-1a, [Score=799, Expect=0.0]} {Celegans: WBGene00003561, ncr-1, Niemann-Pick C1 protein homolog 1, [Score=392, Expect=6e-114]} {Smed: dd_Smed_v6_5175_0_1, dd_Smed_v6_5175_0_1, [Score=837, Expect=0.0]} {RNA1509_2118, RNA1509_23545, RNA1509_24328, RNA1509_49533} {RNA1310_649.1, RNA1509_2118, RNA1509_23545, RNA1509_24328, RNA1509_49533} {RNA1509_2118, RNA1509_23545, RNA1509_24328, RNA1509_49533, RNA815_1096.1}

Cumulative graph for MligTC455_35222

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.089 5.248 0.91306 1.00000
RegionR2 0.051 5.248 0.90070 1.00000
RegionR3 -0.846 5.248 0.01518 0.19866
RegionR4 0.058 5.248 0.88602 1.00000
RegionR5 1.068 5.248 0.00024 0.00328
RegionR6 -0.202 5.248 0.54723 1.00000
RegionR7 -0.012 5.248 0.97700 1.00000
RegionR8 -0.207 5.248 0.66267 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.132 5.248 0.90092 1.00000
RegenerationR2 -0.07 5.248 0.84898 1.00000
RegenerationR3 0.874 5.248 0.04026 0.35279
RegenerationR4 -0.247 5.248 0.56127 0.89753
RegenerationR5 -0.286 5.248 0.44540 0.82794
RegenerationR6 0.297 5.248 0.46892 0.78377
RegenerationBL 0.07 5.248 0.86914 1.00000
RegenerationTP 0.118 5.248 0.79953 1.00000


Genes with expression patterns similar to MligTC455_35222

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_35222 1565 32.6 Mlig455_017065, Mlig455_069841

Neo: Irradiation

Age: logFC(26M/2M)=0.410

Region-enriched R5: 1.068/0.00328

NPC1 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_017065 {REF} {Length: 5970} {TRANSSPLICED} {Pfam: Patched family [PF02460.20, score=253.6]; Sterol-sensing domain of SREBP cleavage-activation [PF12349.10, score=182.9]; Niemann-Pick C1 N terminus [PF16414.7, score=175.1]; MMPL family [PF03176.17, score=19.4]} {Human: ENSG00000141458, NPC1, NPC intracellular cholesterol transporter 1, [Score=824, Expect=0.0]} {Mouse: ENSMUSG00000024413, Npc1, NPC intracellular cholesterol transporter 1, [Score=845, Expect=0.0]} {Dmel: FBgn0024320, Npc1a, Niemann-Pick type C-1a, [Score=796, Expect=0.0]} {Celegans: WBGene00003561, ncr-1, Niemann-Pick C1 protein homolog 1, [Score=393, Expect=3e-114]} {Smed: dd_Smed_v6_5175_0_1, dd_Smed_v6_5175_0_1, [Score=838, Expect=0.0]} {RNA1509_2118} {RNA1310_649.1} {RNA815_1096.1}

Mlig455_069841 {REF} {Length: 6003} {TRANSSPLICED} {Pfam: Patched family [PF02460.20, score=252.9]; Sterol-sensing domain of SREBP cleavage-activation [PF12349.10, score=182.7]; Niemann-Pick C1 N terminus [PF16414.7, score=175.1]; MMPL family [PF03176.17, score=19.4]} {Human: ENSG00000141458, NPC1, NPC intracellular cholesterol transporter 1, [Score=825, Expect=0.0]} {Mouse: ENSMUSG00000024413, Npc1, NPC intracellular cholesterol transporter 1, [Score=846, Expect=0.0]} {Dmel: FBgn0024320, Npc1a, Niemann-Pick type C-1a, [Score=799, Expect=0.0]} {Celegans: WBGene00003561, ncr-1, Niemann-Pick C1 protein homolog 1, [Score=392, Expect=6e-114]} {Smed: dd_Smed_v6_5175_0_1, dd_Smed_v6_5175_0_1, [Score=837, Expect=0.0]} {RNA1509_2118, RNA1509_23545, RNA1509_24328, RNA1509_49533} {RNA1310_649.1, RNA1509_2118, RNA1509_23545, RNA1509_24328, RNA1509_49533} {RNA1509_2118, RNA1509_23545, RNA1509_24328, RNA1509_49533, RNA815_1096.1}
2. MligTC455_35221 789 16.43 Mlig455_059592

Neo: -

Age: logFC(26M/2M)=0.797

Region-enriched R5: 1.111/0.00319

NPC1 5.986 1.000 1.000 0.999 0.992 0.995 1.000 Mlig455_059592 {REF} {Length: 7708} {TRANSSPLICED} {Pfam: Patched family [PF02460.20, score=254.6]; Sterol-sensing domain of SREBP cleavage-activation [PF12349.10, score=182.7]; MMPL family [PF03176.17, score=19.5]} {Human: ENSG00000141458, NPC1, NPC intracellular cholesterol transporter 1, [Score=753, Expect=0.0]} {Mouse: ENSMUSG00000024413, Npc1, NPC intracellular cholesterol transporter 1, [Score=777, Expect=0.0]} {Dmel: FBgn0024320, Npc1a, Niemann-Pick type C-1a, [Score=735, Expect=0.0]} {Celegans: WBGene00003561, ncr-1, Niemann-Pick C1 protein homolog 1, [Score=372, Expect=8e-107]} {Smed: dd_Smed_v6_5175_0_1, dd_Smed_v6_5175_0_1, [Score=765, Expect=0.0]} {RNA1509_2118} {RNA1310_649.1} {RNA815_1096.1}
3. MligTC455_24605 769 16.02 Mlig455_005361, Mlig455_036252

Neo: Irradiation

Age: logFC(26M/2M)=0.249

Region-enriched R5: 1.002/0.04152

CELSR3 2.706 0.900 0.969 - - - 0.837

Mlig455_005361 {REF} {Length: 8997} {TRANSSPLICED} {Pfam: Cadherin domain [PF00028.19, score=434.3]; Laminin G domain [PF02210.26, score=39.5]; GPCR proteolysis site, GPS, motif [PF01825.23, score=37.2]; Laminin G domain [PF00054.25, score=34.1]; Cadherin-like [PF08266.14, score=28.1]; Cadherin-like [PF16184.7, score=27.9]; Laminin EGF domain [PF00053.26, score=25.6]; GPCR-Autoproteolysis INducing (GAIN) domain [PF16489.7, score=19.8]} {Human: ENSG00000008300, CELSR3, cadherin EGF LAG seven-pass G-type receptor 3, [RH, Score=704, Expect=0.0]} {Mouse: ENSMUSG00000023473, Celsr3, cadherin, EGF LAG seven-pass G-type receptor 3, [RH, Score=715, Expect=0.0]; ENSMUSG00000107269, Celsr3, cadherin, EGF LAG seven-pass G-type receptor 3, [RH, Score=715, Expect=0.0]; ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [RH, Score=714, Expect=0.0]; ENSMUSG00000016028, Celsr1, cadherin, EGF LAG seven-pass G-type receptor 1, [RH, Score=687, Expect=0.0]} {Dmel: FBgn0024836, stan, starry night, [RH, Score=711, Expect=0.0]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=418, Expect=3e-117]} {Smed: dd_Smed_v6_16629_0_1, dd_Smed_v6_16629_0_1, [Score=239, Expect=4e-64]} {RNA1509_8917} {RNA1310_144} {RNA815_3427}

Mlig455_036252 {REF} {Length: 9107} {TRANSSPLICED} {Pfam: Cadherin domain [PF00028.19, score=468.5]; Laminin G domain [PF02210.26, score=39.5]; GPCR proteolysis site, GPS, motif [PF01825.23, score=37.2]; Laminin G domain [PF00054.25, score=34.0]; Cadherin-like [PF08266.14, score=31.0]; Cadherin-like [PF16184.7, score=31.0]; Laminin EGF domain [PF00053.26, score=25.6]; GPCR-Autoproteolysis INducing (GAIN) domain [PF16489.7, score=19.8]} {Human: ENSG00000008300, CELSR3, cadherin EGF LAG seven-pass G-type receptor 3, [RH, Score=727, Expect=0.0]; ENSG00000143126, CELSR2, cadherin EGF LAG seven-pass G-type receptor 2, [RH, Score=726, Expect=0.0]} {Mouse: ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [RH, Score=738, Expect=0.0]; ENSMUSG00000023473, Celsr3, cadherin, EGF LAG seven-pass G-type receptor 3, [RH, Score=738, Expect=0.0]; ENSMUSG00000107269, Celsr3, cadherin, EGF LAG seven-pass G-type receptor 3, [RH, Score=738, Expect=0.0]; ENSMUSG00000016028, Celsr1, cadherin, EGF LAG seven-pass G-type receptor 1, [RH, Score=714, Expect=0.0]} {Dmel: FBgn0024836, stan, starry night, [RH, Score=741, Expect=0.0]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [RH, Score=439, Expect=8e-124]} {Smed: dd_Smed_v6_16629_0_1, dd_Smed_v6_16629_0_1, [Score=253, Expect=2e-68]} {RNA1509_8917} {RNA1310_144, RNA1509_8917} {RNA1509_8917, RNA815_3429}
4. MligTC455_24604 376 7.83 Mlig455_005489

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.381

CELSR2 2.678 0.888 0.959 - - - 0.831 Mlig455_005489 {REF} {Length: 9041} {TRANSSPLICED} {Pfam: Cadherin domain [PF00028.19, score=468.3]; Laminin G domain [PF02210.26, score=40.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=37.2]; Laminin G domain [PF00054.25, score=34.3]; Cadherin-like [PF08266.14, score=33.8]; Cadherin-like [PF16184.7, score=31.0]; Laminin EGF domain [PF00053.26, score=25.6]; GPCR-Autoproteolysis INducing (GAIN) domain [PF16489.7, score=21.2]} {Human: ENSG00000143126, CELSR2, cadherin EGF LAG seven-pass G-type receptor 2, [RH, Score=726, Expect=0.0]; ENSG00000008300, CELSR3, cadherin EGF LAG seven-pass G-type receptor 3, [RH, Score=724, Expect=0.0]} {Mouse: ENSMUSG00000023473, Celsr3, cadherin, EGF LAG seven-pass G-type receptor 3, [RH, Score=736, Expect=0.0]; ENSMUSG00000107269, Celsr3, cadherin, EGF LAG seven-pass G-type receptor 3, [RH, Score=736, Expect=0.0]; ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [RH, Score=734, Expect=0.0]} {Dmel: FBgn0024836, stan, starry night, [RH, Score=743, Expect=0.0]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [RH, Score=435, Expect=2e-122]} {Smed: dd_Smed_v6_16629_0_1, dd_Smed_v6_16629_0_1, [Score=256, Expect=3e-69]} {RNA1509_8917} {RNA1310_144} {RNA815_3429}
5. MligTC455_51178 190 3.97 Mlig455_066114

Neo: -

Age: -

0.975 - - - - - 0.975 Mlig455_066114 {REF} {Length: 2408} {Smed: dd_Smed_v6_70006_0_1, dd_Smed_v6_70006_0_1, [Score=58.5, Expect=4e-10]} {RNA1509_36492} {RNA1310_14560, RNA1509_36492} {RNA1509_36492, RNA815_5366}
6. MligTC455_35744 922 19.22 Mlig455_038709, Mlig455_068406

Neo: -

Age: -

Region-enriched R8: 1.806/0.00372
Region-enriched R5: 1.369/0.00001

0.961 - - - - - 0.961

Mlig455_038709 {REF} {Length: 3432} {Pfam: PH domain [PF00169.31, score=29.2]} {RNA1509_15848} {RNA1310_10672} {RNA815_4038}

Mlig455_068406 {REF} {Length: 2737} {Pfam: PH domain [PF00169.31, score=29.2]} {RNA1509_15848} {RNA1310_10672} {RNA815_4038}
7. MligTC455_44379 1600 33.34 Mlig455_010857, Mlig455_010889, Mlig455_033207

Neo: -

Age: -

C1GALT1 0.956 - - - - - 0.956

Mlig455_010857 {REF} {Length: 1465} {TRANSSPLICED} {Pfam: Fringe-like [PF02434.18, score=49.3]; Galactosyltransferase [PF01762.23, score=25.9]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=274, Expect=2e-89]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=269, Expect=1e-87]} {Dmel: FBgn0033271, CG8708, [Score=269, Expect=9e-87]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=280, Expect=9e-92]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=273, Expect=7e-90]} {RNA1509_22923} {RNA1310_21878} {RNA815_9240}

Mlig455_010889 {REF} {Length: 1465} {TRANSSPLICED} {Pfam: Fringe-like [PF02434.18, score=50.4]; Galactosyltransferase [PF01762.23, score=25.3]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=272, Expect=9e-89]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=267, Expect=4e-87]} {Dmel: FBgn0033271, CG8708, [Score=266, Expect=1e-85]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=279, Expect=1e-91]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=276, Expect=5e-91]} {RNA1509_22923} {RNA1310_21878} {RNA815_9240}

Mlig455_033207 {REF} {Length: 1463} {TRANSSPLICED} {Pfam: Fringe-like [PF02434.18, score=49.5]; Galactosyltransferase [PF01762.23, score=25.1]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=274, Expect=2e-89]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=269, Expect=9e-88]} {Dmel: FBgn0033271, CG8708, [Score=268, Expect=2e-86]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=281, Expect=3e-92]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=275, Expect=2e-90]} {RNA1509_22923} {RNA1310_21878, RNA1509_22923} {RNA1509_22923, RNA815_9240}
8. MligTC455_19333 445 9.26 Mlig455_033842

Neo: -

Age: -

SF3A2 0.954 - 0.954 - - - - Mlig455_033842 {REF} {Length: 7226} {TRANSSPLICED} {Pfam: Laminin Domain II [PF06009.14, score=23.1]} {Human: ENSG00000104897, SF3A2, splicing factor 3a subunit 2, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000020211, Sf3a2, splicing factor 3a, subunit 2, [Score=69.3, Expect=1e-11]} {Smed: dd_Smed_v6_7590_0_1, dd_Smed_v6_7590_0_1, [Score=77.4, Expect=3e-15]} {RNA1509_9214} {RNA1310_3191} {RNA815_12808}

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