Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_35316 | 108 | 2.24 | Mlig455_038442 | Neo: Germline Age: Down-Up-Down Region-enriched R7: 3.366/0.00737 |
ADHFE1 | Mlig455_038442 {REF} {Length: 3619} {TRANSSPLICED} {Pfam: Iron-containing alcohol dehydrogenase [PF00465.21, score=346.3]; FAR-17a/AIG1-like protein [PF04750.16, score=102.5]; Iron-containing alcohol dehydrogenase [PF13685.8, score=51.9]; Periplasmic binding protein [PF13458.8, score=20.2]} {Human: ENSG00000147576, ADHFE1, alcohol dehydrogenase, iron containing 1, [RH, Score=509, Expect=3e-176]} {Mouse: ENSMUSG00000025911, Adhfe1, alcohol dehydrogenase, iron containing, 1, [RH, Score=506, Expect=2e-175]} {Dmel: FBgn0017482, T3dh, Type III alcohol dehydrogenase, [RH, Score=489, Expect=1e-168]} {Celegans: WBGene00012608, hphd-1, Hydroxyacid-oxoacid transhydrogenase, mitochondrial, [RH, Score=443, Expect=9e-151]} {Smed: dd_Smed_v6_4554_0_2, dd_Smed_v6_4554_0_2, [RH, Score=491, Expect=2e-169]} {RNA1509_2515} {RNA1310_11167.1} {RNA815_5063} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -5.925 | 1.826 | 0.18095 | 0.80994 | |
RegionR2 | -4.121 | 1.826 | 0.99993 | 1.00000 | |
RegionR3 | 0.415 | 1.826 | 0.63061 | 1.00000 | |
RegionR4 | 2.71 | 1.826 | 0.03349 | 0.14676 | |
RegionR5 | 2.03 | 1.826 | 0.04007 | 0.15966 | |
RegionR6 | 1.204 | 1.826 | 0.24553 | 0.83123 | |
RegionR7 | 3.366 | 1.826 | 0.00014 | 0.00737 | |
RegionR8 | 0.322 | 1.826 | 0.78540 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.362 | 1.826 | 1.00000 | 1.00000 | |
RegenerationR2 | 1.762 | 1.826 | 0.19739 | 0.64245 | |
RegenerationR3 | -0.921 | 1.826 | 0.36902 | 0.78341 | |
RegenerationR4 | 0.067 | 1.826 | 0.96477 | 1.00000 | |
RegenerationR5 | -1.775 | 1.826 | 0.06636 | 0.40588 | |
RegenerationR6 | -1.729 | 1.826 | 0.12688 | 0.43814 | |
RegenerationBL | -6.829 | 1.826 | 0.00206 | 0.03686 | |
RegenerationTP | -3.075 | 1.826 | 0.02328 | 0.25877 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_35316 | 108 | 2.24 | Mlig455_038442 | Neo: Germline Age: Down-Up-Down Region-enriched R7: 3.366/0.00737 |
ADHFE1 | 5 | 1.000 | 1.000 | 1.000 | 1.000 | - | 1.000 | Mlig455_038442 {REF} {Length: 3619} {TRANSSPLICED} {Pfam: Iron-containing alcohol dehydrogenase [PF00465.21, score=346.3]; FAR-17a/AIG1-like protein [PF04750.16, score=102.5]; Iron-containing alcohol dehydrogenase [PF13685.8, score=51.9]; Periplasmic binding protein [PF13458.8, score=20.2]} {Human: ENSG00000147576, ADHFE1, alcohol dehydrogenase, iron containing 1, [RH, Score=509, Expect=3e-176]} {Mouse: ENSMUSG00000025911, Adhfe1, alcohol dehydrogenase, iron containing, 1, [RH, Score=506, Expect=2e-175]} {Dmel: FBgn0017482, T3dh, Type III alcohol dehydrogenase, [RH, Score=489, Expect=1e-168]} {Celegans: WBGene00012608, hphd-1, Hydroxyacid-oxoacid transhydrogenase, mitochondrial, [RH, Score=443, Expect=9e-151]} {Smed: dd_Smed_v6_4554_0_2, dd_Smed_v6_4554_0_2, [RH, Score=491, Expect=2e-169]} {RNA1509_2515} {RNA1310_11167.1} {RNA815_5063} |
2. | MligTC455_51390 | 1752 | 36.49 | Mlig455_040781, Mlig455_064616 | Neo: - Age: - Region-specific R4: 2.961 Region-enriched R1: 2.440/0.03099 Regeneration-downregulated R4: -1.700 Regeneration-depleted R4: -1.700 |
PM20D1 | 1.74 | - | - | - | 0.952 | - | 0.788 | Mlig455_040781 {REF} {Length: 1898} {Pfam: Peptidase family M20/M25/M40 [PF01546.30, score=84.3]; Peptidase family M28 [PF04389.19, score=27.8]; M42 glutamyl aminopeptidase [PF05343.16, score=18.1]} {Human: ENSG00000162877, PM20D1, peptidase M20 domain containing 1, [Score=147, Expect=5e-39]} {Mouse: ENSMUSG00000042251, Pm20d1, peptidase M20 domain containing 1, [Score=169, Expect=3e-47]} {Dmel: FBgn0039053, CG6738, [Score=66.6, Expect=8e-12]} {Celegans: WBGene00007509, C10C5.5, Aminoacylase, [Score=64.7, Expect=3e-11]} {Smed: dd_Smed_v6_1519_0_1, dd_Smed_v6_1519_0_1, [Score=60.8, Expect=3e-10]} {RNA1509_3745} {RNA1310_3346} {RNA815_5291} Mlig455_064616 {REF} {Length: 1988} {Pfam: Peptidase family M20/M25/M40 [PF01546.30, score=114.7]; Peptidase dimerisation domain [PF07687.16, score=50.7]; Peptidase family M28 [PF04389.19, score=26.8]; M42 glutamyl aminopeptidase [PF05343.16, score=17.9]} {Human: ENSG00000162877, PM20D1, peptidase M20 domain containing 1, [RH, Score=355, Expect=8e-117]} {Mouse: ENSMUSG00000042251, Pm20d1, peptidase M20 domain containing 1, [RH, Score=388, Expect=4e-130]} {Dmel: FBgn0039051, CG17109, [Score=73.9, Expect=6e-14]} {Celegans: WBGene00007507, C10C5.3, Aminoacylase, [Score=75.9, Expect=1e-14]} {Smed: dd_Smed_v6_1519_0_1, dd_Smed_v6_1519_0_1, [Score=62.4, Expect=2e-10]} {RNA1509_3745} {RNA1310_3185.1} {RNA815_5291} |
3. | MligTC455_11214 | 227 | 4.72 | Mlig455_041296, Mlig455_056196 | Neo: Germline Age: Up-Down-Down Region-specific R4: 5.610 Region-enriched R4: 4.997/0.00000 |
1.683 | - | - | - | 0.952 | - | 0.731 | Mlig455_041296 {REF} {Length: 2230} {Mouse: ENSMUSG00000038522, Mfsd4b1, major facilitator superfamily domain containing 4B1, [Score=67.8, Expect=1e-11]; ENSMUSG00000071335, Mfsd4b3, major facilitator superfamily domain containing 4B3, [Score=64.7, Expect=8e-11]} {RNA1509_25958} {RNA1310_9369} {RNA815_37361} Mlig455_056196 {REF} {Length: 2701} {Mouse: ENSMUSG00000038522, Mfsd4b1, major facilitator superfamily domain containing 4B1, [Score=67.8, Expect=1e-11]; ENSMUSG00000071335, Mfsd4b3, major facilitator superfamily domain containing 4B3, [Score=64.7, Expect=8e-11]} {RNA1509_25958} {RNA1310_9369, RNA1509_25958} {RNA1509_25958, RNA815_37361} |
|
4. | MligTC455_14454 | 97 | 2.02 | Mlig455_023038 | Neo: - Age: - Region-enriched R7: 5.711/0.00182 |
MFSD4A | 1.667 | 0.961 | 0.706 | - | - | - | - | Mlig455_023038 {REF} {Length: 2825} {Human: ENSG00000174514, MFSD4A, major facilitator superfamily domain containing 4A, [Score=132, Expect=1e-32]} {Mouse: ENSMUSG00000059149, Mfsd4a, major facilitator superfamily domain containing 4A, [Score=139, Expect=5e-35]} {Smed: dd_Smed_v6_10372_0_1, dd_Smed_v6_10372_0_1, [RH, Score=179, Expect=3e-50]} {RNA1310_6462.1} {RNA815_29662} |
5. | MligTC455_44448 | 16 | 0.34 | Mlig455_034413 | Neo: - Age: - |
0.977 | 0.977 | - | - | - | - | - | Mlig455_034413 {REF} {Length: 161} {NoTransDecoderORF} {tRNA: Thr(CGT), score=78.3} | |
6. | MligTC455_22151 | 1286 | 26.78 | Mlig455_054961 | Neo: - Age: Down-Up-Down Region-enriched R4: 2.174/0.00000 |
XDH | 0.967 | - | - | - | 0.967 | - | - | Mlig455_054961 {REF} {Length: 8931} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=746.5]; [2Fe-2S] binding domain [PF01799.22, score=187.9]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=151.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=115.0]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=110.3]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=28.4]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=490, Expect=1e-144]; ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=472, Expect=2e-138]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=496, Expect=5e-147]; ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=472, Expect=7e-139]} {Dmel: FBgn0038349, AOX3, Aldehyde oxidase 3, [RH, Score=658, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=501, Expect=1e-148]} {RNA1509_48253} {RNA1310_3150.1} {RNA815_224.3} |
7. | MligTC455_43060 | 1009 | 21.02 | Mlig455_008729, Mlig455_063590, Mlig455_063598 | Neo: - Age: Up-Down-Down, logFC(26M/2M)=-0.267 Region-enriched R4: 1.627/0.02617 |
GGT1 | 0.964 | - | - | - | 0.964 | - | - | Mlig455_008729 {REF} {Length: 3645} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=528.0]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=416, Expect=3e-138]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [Score=382, Expect=2e-125]} {Dmel: FBgn0025837, CG17636, [RH, Score=349, Expect=6e-113]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=382, Expect=9e-125]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=453, Expect=7e-153]} {RNA1509_59755} {RNA1310_13419.1} {RNA815_9027} Mlig455_063590 {REF} {Length: 2177} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=231.2]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [Score=162, Expect=7e-46]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [Score=143, Expect=9e-38]} {Dmel: FBgn0030796, CG4829, [Score=153, Expect=5e-41]} {Celegans: WBGene00011393, T03D8.6, [Score=162, Expect=9e-45]} {Smed: dd_Smed_v6_4591_0_3, dd_Smed_v6_4591_0_3, [Score=196, Expect=2e-58]} {RNA1509_43652, RNA1509_59755} {RNA1310_13419.1, RNA1509_43652} {RNA1509_43652, RNA815_9027} Mlig455_063598 {REF} {Length: 3697} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=526.4]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=414, Expect=2e-137]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [Score=379, Expect=2e-124]} {Dmel: FBgn0025837, CG17636, [RH, Score=349, Expect=1e-112]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=381, Expect=7e-125]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=452, Expect=1e-152]} {RNA1509_59755} {RNA1310_13419.1} {RNA815_9027} |
8. | MligTC455_28453 | 348 | 7.25 | Mlig455_061725, Mlig455_061755 | Neo: Germline Age: Up-Down-Down, logFC(26M/2M)=-0.333 Region-specific R4: 4.354 |
ABCA1 | 0.959 | - | - | - | 0.959 | - | - | Mlig455_061725 {REF} {Length: 7872} {Pfam: ABC-2 family transporter protein [PF12698.9, score=183.3]; ABC transporter [PF00005.29, score=176.5]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=71.3]; AAA domain [PF13476.8, score=23.3]; AAA ATPase domain [PF13175.8, score=20.7]} {Human: ENSG00000165029, ABCA1, ATP binding cassette subfamily A member 1, [RH, Score=1228, Expect=0.0]} {Mouse: ENSMUSG00000015243, Abca1, ATP-binding cassette, sub-family A (ABC1), member 1, [RH, Score=1229, Expect=0.0]; ENSMUSG00000028125, Abca4, ATP-binding cassette, sub-family A (ABC1), member 4, [RH, Score=1168, Expect=0.0]} {Dmel: FBgn0031170, CG1718, [Score=443, Expect=2e-127]} {Celegans: WBGene00000022, abt-4, ABC Transporter family, [RH, Score=415, Expect=1e-117]} {Smed: dd_Smed_v6_2300_0_2, dd_Smed_v6_2300_0_2, [RH, Score=1170, Expect=0.0]} {RNA1509_54611} {RNA1310_2227} {RNA815_1429} Mlig455_061755 {REF} {Length: 8216} {Pfam: ABC transporter [PF00005.29, score=175.3]; ABC-2 family transporter protein [PF12698.9, score=169.3]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=71.1]; AAA domain [PF13476.8, score=23.1]; AAA ATPase domain [PF13175.8, score=20.0]} {Human: ENSG00000165029, ABCA1, ATP binding cassette subfamily A member 1, [RH, Score=1226, Expect=0.0]} {Mouse: ENSMUSG00000015243, Abca1, ATP-binding cassette, sub-family A (ABC1), member 1, [RH, Score=1226, Expect=0.0]} {Dmel: FBgn0031170, CG1718, [Score=447, Expect=2e-128]} {Celegans: WBGene00000022, abt-4, ABC Transporter family, [RH, Score=414, Expect=3e-117]} {Smed: dd_Smed_v6_2300_0_2, dd_Smed_v6_2300_0_2, [RH, Score=1167, Expect=0.0]} {RNA1509_9108} {RNA1310_2227} {RNA815_1429} |
9. | MligTC455_51882 | 911 | 18.99 | Mlig455_036838, Mlig455_052977, Mlig455_053038 | Neo: - Age: logFC(26M/2M)=0.535 Region-enriched R4: 3.812/0.00000 |
ANK2 | 0.958 | - | - | - | 0.958 | - | - | Mlig455_036838 {REF} {Length: 3082} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=92.5]; Ankyrin repeats (3 copies) [PF12796.9, score=88.5]; Ankyrin repeat [PF13606.8, score=66.9]; Ankyrin repeat [PF00023.32, score=61.3]; Ankyrin repeats (many copies) [PF13857.8, score=58.3]; Mab-21 protein [PF03281.16, score=29.1]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=84.7, Expect=6e-16]; ENSG00000170209, ANKK1, ankyrin repeat and kinase domain containing 1, [Score=82.8, Expect=2e-15]; ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [Score=82.0, Expect=2e-15]; ENSG00000029534, ANK1, ankyrin 1, [Score=81.6, Expect=5e-15]; ENSG00000206560, ANKRD28, ankyrin repeat domain 28, [Score=80.5, Expect=8e-15]} {Mouse: ENSMUSG00000032257, Ankk1, ankyrin repeat and kinase domain containing 1, [Score=92.0, Expect=1e-18]; ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=90.9, Expect=3e-18]} {Dmel: FBgn0031473, CG3104, [Score=87.4, Expect=3e-18]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=79.0, Expect=1e-14]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=85.1, Expect=1e-16]} {RNA1509_21275} {RNA1310_6086} {RNA815_930} Mlig455_052977 {REF} {Length: 3059} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=91.0]; Ankyrin repeats (3 copies) [PF12796.9, score=88.1]; Ankyrin repeat [PF13606.8, score=65.6]; Ankyrin repeat [PF00023.32, score=63.0]; Ankyrin repeats (many copies) [PF13857.8, score=58.4]; Mab-21 protein [PF03281.16, score=29.1]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=85.1, Expect=5e-16]; ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=84.7, Expect=5e-16]; ENSG00000170209, ANKK1, ankyrin repeat and kinase domain containing 1, [Score=83.6, Expect=9e-16]; ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [Score=82.4, Expect=1e-15]; ENSG00000135299, ANKRD6, ankyrin repeat domain 6, [Score=82.0, Expect=3e-15]; ENSG00000029534, ANK1, ankyrin 1, [Score=81.3, Expect=6e-15]} {Mouse: ENSMUSG00000032257, Ankk1, ankyrin repeat and kinase domain containing 1, [Score=92.8, Expect=8e-19]; ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=89.7, Expect=9e-18]} {Dmel: FBgn0031473, CG3104, [Score=87.8, Expect=2e-18]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=80.9, Expect=4e-15]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=85.9, Expect=8e-17]} {RNA1509_21275} {RNA1310_6086} {RNA815_930} Mlig455_053038 {REF} {Length: 3082} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=92.5]; Ankyrin repeats (3 copies) [PF12796.9, score=88.5]; Ankyrin repeat [PF13606.8, score=66.9]; Ankyrin repeat [PF00023.32, score=61.3]; Ankyrin repeats (many copies) [PF13857.8, score=58.3]; Mab-21 protein [PF03281.16, score=29.1]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=85.1, Expect=5e-16]; ENSG00000170209, ANKK1, ankyrin repeat and kinase domain containing 1, [Score=82.8, Expect=1e-15]; ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [Score=82.0, Expect=2e-15]; ENSG00000029534, ANK1, ankyrin 1, [Score=81.6, Expect=5e-15]; ENSG00000206560, ANKRD28, ankyrin repeat domain 28, [Score=80.9, Expect=8e-15]} {Mouse: ENSMUSG00000032257, Ankk1, ankyrin repeat and kinase domain containing 1, [Score=92.4, Expect=1e-18]; ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=91.3, Expect=3e-18]} {Dmel: FBgn0031473, CG3104, [Score=87.4, Expect=3e-18]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=79.7, Expect=9e-15]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=85.1, Expect=1e-16]} {RNA1509_21275} {RNA1310_6086, RNA1509_21275} {RNA1509_21275, RNA815_930} |
10. | MligTC455_15262 | 19 | 0.4 | Mlig455_012031 | Neo: - Age: - |
0.953 | 0.953 | - | - | - | - | - | Mlig455_012031 {REF} {Length: 1692} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=49.7]} {Smed: dd_Smed_v6_9777_0_1, dd_Smed_v6_9777_0_1, [Score=184, Expect=2e-56]} {RNA1310_47067} {RNA815_29511.1} | |
11. | MligTC455_26907 | 242 | 5.05 | Mlig455_019220 | Neo: - Age: - Region-enriched R3: 4.556/0.00000 |
F5 | 0.95 | - | - | - | 0.950 | - | - | Mlig455_019220 {REF} {Length: 5657} {Human: ENSG00000198734, F5, coagulation factor V, [Score=75.1, Expect=1e-12]} {RNA1509_28476, RNA1509_31695, RNA1509_39871} {RNA1310_25950, RNA1509_28476, RNA1509_31695, RNA1509_39871} {RNA1509_28476, RNA1509_31695, RNA1509_39871, RNA815_16964} |
12. | MligTC455_35961 | 157 | 3.27 | Mlig455_022635 | Neo: - Age: - Region-enriched R3: 2.638/0.01129 |
0.95 | - | - | - | 0.950 | - | - | Mlig455_022635 {REF} {Length: 5813} {TRANSSPLICED} {Pfam: Glycosyl hydrolase family 63 C-terminal domain [PF03200.18, score=28.0]; Protein of unknown function (DUF4232) [PF14016.8, score=20.2]} {RNA1509_28884, RNA1509_9146} {RNA1310_4028.1, RNA1509_28884} {RNA1509_28884, RNA815_1420} |