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Results for MligTC455_36090

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_36090 14 0.28 Mlig455_039249

Neo: -

Age: Up-Down-Up

 Mlig455_039249 {REF} {Length: 2858} {TRANSSPLICED} {RNA1509_30307} {RNA1310_674, RNA1509_30307} {RNA1509_30307, RNA815_24710}

Cumulative graph for MligTC455_36090

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.464 0.706 1.00000 1.00000
RegionR2 2.762 0.706 0.98818 1.00000
RegionR3 0.466 0.706 0.99912 1.00000
RegionR4 0.162 0.706 0.24596 0.54416
RegionR5 -0.492 0.706 0.99858 1.00000
RegionR6 0.955 0.706 0.99966 1.00000
RegionR7 -1.299 0.706 1.00000 1.00000
RegionR8 -1.09 0.706 0.99980 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.162 0.706 0.99978 1.00000
RegenerationR2 -3.335 0.706 0.09740 0.49555
RegenerationR3 0.216 0.706 0.20493 0.63992
RegenerationR4 -1.173 0.706 0.09446 0.47881
RegenerationR5 -1.715 0.706 0.08569 0.45125
RegenerationR6 -1.629 0.706 0.16205 0.49125
RegenerationBL -0.986 0.706 1.00000 1.00000
RegenerationTP -0.155 0.706 0.99988 1.00000


Genes with expression patterns similar to MligTC455_36090

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_36090 14 0.28 Mlig455_039249

Neo: -

Age: Up-Down-Up

 3 1.000 - 1.000 - 1.000 - Mlig455_039249 {REF} {Length: 2858} {TRANSSPLICED} {RNA1509_30307} {RNA1310_674, RNA1509_30307} {RNA1509_30307, RNA815_24710}
2. MligTC455_04170 65 1.36 Mlig455_000555, Mlig455_030353

Neo: -

Age: -

 FGG 1.949 - - 0.970 - 0.979 -

Mlig455_000555 {REF} {Length: 1133} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=125.0]} {Human: ENSG00000171557, FGG, fibrinogen gamma chain, [Score=103, Expect=3e-24]; ENSG00000120332, TNN, tenascin N, [Score=98.2, Expect=3e-22]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=102, Expect=6e-25]; ENSMUSG00000026938, Fcna, ficolin A, [Score=99.4, Expect=1e-23]; ENSMUSG00000033860, Fgg, fibrinogen gamma chain, [Score=98.2, Expect=9e-23]; ENSMUSG00000026725, Tnn, tenascin N, [Score=98.2, Expect=2e-22]} {Dmel: FBgn0051832, CG31832, [Score=88.2, Expect=2e-20]} {Celegans: WBGene00020516, T15B7.1, [Score=62.4, Expect=8e-11]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=72.4, Expect=4e-14]} {RNA1310_33683.2} {RNA815_41841}

Mlig455_030353 {REF} {Length: 1214} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=126.3]} {Human: ENSG00000171557, FGG, fibrinogen gamma chain, [Score=103, Expect=3e-24]; ENSG00000120332, TNN, tenascin N, [Score=99.4, Expect=3e-22]; ENSG00000160339, FCN2, ficolin 2, [Score=98.2, Expect=6e-23]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=102, Expect=1e-24]; ENSMUSG00000026938, Fcna, ficolin A, [Score=100, Expect=1e-23]; ENSMUSG00000026725, Tnn, tenascin N, [Score=99.0, Expect=2e-22]; ENSMUSG00000033860, Fgg, fibrinogen gamma chain, [Score=99.0, Expect=9e-23]} {Dmel: FBgn0051832, CG31832, [Score=92.0, Expect=9e-22]} {Celegans: WBGene00020516, T15B7.1, [Score=63.2, Expect=4e-11]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=75.9, Expect=4e-15]} {RNA1310_33683.2} {RNA815_41841}
3. MligTC455_51009 16 0.33 Mlig455_057754

Neo: -

Age: -

 1.949 - - 0.967 - 0.982 - Mlig455_057754 {REF} {Length: 198} {NoTransDecoderORF}
4. MligTC455_20225 18 0.38 Mlig455_042403

Neo: -

Age: -

 1.941 - - 0.959 - 0.982 - Mlig455_042403 {REF} {Length: 1402} {Pfam: WSC domain [PF01822.21, score=50.0]; PAN domain [PF00024.28, score=21.0]} {RNA1310_77268} {RNA815_27180}
5. MligTC455_43455 20 0.42 Mlig455_050690

Neo: -

Age: -

 1.925 - - 0.948 - 0.977 - Mlig455_050690 {REF} {Length: 2482} {Dmel: FBgn0259222, CG42322, [RH, Score=100, Expect=5e-22]} {Smed: dd_Smed_v6_18554_0_1, dd_Smed_v6_18554_0_1, [Score=82.4, Expect=1e-17]} {RNA1310_20749} {RNA815_38231}
6. MligTC455_03368 10 0.21 Mlig455_056536

Neo: -

Age: -

 HTR3A 1.924 - - 0.942 - 0.982 - Mlig455_056536 {REF} {Length: 1346} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=109.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=82.9]} {Human: ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=132, Expect=1e-33]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=126, Expect=1e-31]} {Mouse: ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=137, Expect=3e-35]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=122, Expect=5e-30]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=137, Expect=2e-35]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=126, Expect=1e-31]} {RNA1509_7752} {RNA1310_1750.2} {RNA815_6234}
7. MligTC455_37991 22 0.46 Mlig455_018140

Neo: -

Age: -

 1.924 - - 0.942 - 0.982 - Mlig455_018140 {REF} {Length: 2598} {Pfam: EF-hand domain pair [PF13499.8, score=36.8]; EF-hand domain [PF13405.8, score=31.2]; EF hand [PF00036.34, score=29.3]; EF-hand domain pair [PF13833.8, score=20.5]; EF hand [PF13202.8, score=19.4]} {Smed: dd_Smed_v6_1010_0_1, dd_Smed_v6_1010_0_1, [Score=104, Expect=1e-26]} {RNA1310_31713.2} {RNA815_36423}
8. MligTC455_11713 8 0.16 Mlig455_030060

Neo: -

Age: -

 1.923 - - 0.941 - 0.982 - Mlig455_030060 {REF} {Length: 1189} {RNA1310_40798} {RNA815_26160}
9. MligTC455_18888 63 1.31 Mlig455_011646, Mlig455_049904

Neo: -

Age: Up-Up-Down

 1.923 - - 0.941 - 0.982 -

Mlig455_011646 {REF} {Length: 92} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_37293} {RNA1310_21789} {RNA815_13092}

Mlig455_049904 {REF} {Length: 92} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_37293} {RNA1310_21789} {RNA815_13092}
10. MligTC455_39392 3 0.05 Mlig455_042341

Neo: -

Age: -

 1.923 - - 0.941 - 0.982 - Mlig455_042341 {REF} {Length: 943} {Pfam: PAN domain [PF00024.28, score=20.9]} {RNA1509_56220} {RNA1310_77268} {RNA815_27180}
11. MligTC455_50828 27 0.57 Mlig455_037962

Neo: -

Age: -

 WSCD2 1.918 - - 0.927 - 0.991 - Mlig455_037962 {REF} {Length: 911} {Pfam: WSC domain [PF01822.21, score=58.4]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.8, Expect=1e-07]; ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=50.8, Expect=5e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=53.9, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=55.5, Expect=7e-09]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=46.2, Expect=8e-06]} {RNA1509_59284} {RNA1310_52794.1} {RNA815_21749.1}
12. MligTC455_05753 20 0.43 Mlig455_046443, Mlig455_046475

Neo: -

Age: -

 1.915 - - 0.972 - 0.943 -

Mlig455_046443 {REF} {Length: 1972} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=89.6]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=47.0]; Taste receptor protein (TAS2R) [PF05296.15, score=25.1]} {Dmel: FBgn0264002, MsR2, Myosuppressin receptor 2, [Score=86.3, Expect=8e-18]} {Celegans: WBGene00016428, dmsr-7, DroMyoSuppressin Receptor related, [Score=84.7, Expect=1e-17]} {Smed: dd_Smed_v6_17590_0_1, dd_Smed_v6_17590_0_1, [Score=141, Expect=9e-38]} {RNA1310_111897}

Mlig455_046475 {REF} {Length: 1474} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=90.2]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=46.5]; Taste receptor protein (TAS2R) [PF05296.15, score=24.9]} {Dmel: FBgn0264002, MsR2, Myosuppressin receptor 2, [Score=86.7, Expect=7e-18]} {Celegans: WBGene00016428, dmsr-7, DroMyoSuppressin Receptor related, [Score=85.5, Expect=7e-18]} {Smed: dd_Smed_v6_17590_0_1, dd_Smed_v6_17590_0_1, [Score=142, Expect=1e-37]} {RNA1310_111897}
13. MligTC455_16780 59 1.22 Mlig455_003112, Mlig455_062777

Neo: -

Age: -

 1.912 - - 0.926 - 0.986 -

Mlig455_003112 {REF} {Length: 1644} {Pfam: PAN domain [PF14295.8, score=23.1]} {RNA1509_48973} {RNA1310_82250} {RNA815_43010}

Mlig455_062777 {REF} {Length: 1721} {RNA1509_48973} {RNA1310_82250} {RNA815_43010}
14. MligTC455_50026 11 0.23 Mlig455_040800

Neo: -

Age: -

 SIDT1 1.896 - - 0.942 - 0.954 - Mlig455_040800 {REF} {Length: 3056} {Pfam: dsRNA-gated channel SID-1 [PF13965.8, score=567.3]} {Human: ENSG00000072858, SIDT1, SID1 transmembrane family member 1, [Score=486, Expect=1e-160]} {Mouse: ENSMUSG00000022696, Sidt1, SID1 transmembrane family, member 1, [Score=352, Expect=1e-109]; ENSMUSG00000034908, Sidt2, SID1 transmembrane family, member 2, [Score=342, Expect=9e-106]} {Celegans: WBGene00006477, chup-1, CHolesterol UPtake associated, [RH, Score=338, Expect=3e-105]} {Smed: dd_Smed_v6_6063_0_2, dd_Smed_v6_6063_0_2, [Score=413, Expect=2e-133]} {RNA1509_16281} {RNA1310_78145} {RNA815_1619.1}
15. MligTC455_14752 17 0.36 Mlig455_009102

Neo: -

Age: -

 1.895 - - 0.976 - 0.919 - Mlig455_009102 {REF} {Length: 1690} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=50.9]; Capsular polysaccharide synthesis protein [PF05704.14, score=18.3]} {Smed: dd_Smed_v6_9783_0_1, dd_Smed_v6_9783_0_1, [Score=89.7, Expect=1e-19]} {RNA1509_4484} {RNA1310_25467} {RNA815_39314}
16. MligTC455_12472 8 0.17 Mlig455_008386

Neo: -

Age: -

 1.891 - - 0.909 - 0.982 - Mlig455_008386 {REF} {Length: 1982} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=59.1]} {Smed: dd_Smed_v6_18754_0_1, dd_Smed_v6_18754_0_1, [Score=118, Expect=2e-29]}
17. MligTC455_13628 4 0.08 Mlig455_065477

Neo: -

Age: -

 1.891 - - 0.909 - 0.982 - Mlig455_065477 {REF} {Length: 1546} {RNA1310_94530} {RNA815_49408}
18. MligTC455_50827 107 2.22 Mlig455_037867

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.688

 WSCD2 1.891 - - 0.912 - 0.979 - Mlig455_037867 {REF} {Length: 912} {Pfam: WSC domain [PF01822.21, score=58.4]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.8, Expect=1e-07]; ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=50.4, Expect=5e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=53.9, Expect=4e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.9, Expect=2e-08]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=46.2, Expect=8e-06]} {RNA1509_59284} {RNA1310_52794.1} {RNA815_21749.1}
19. MligTC455_43084 5 0.11 Mlig455_035337

Neo: -

Age: -

 1.868 - - 0.886 - 0.982 - Mlig455_035337 {REF} {Length: 1065} {Pfam: Lectin C-type domain [PF00059.23, score=29.5]} {Smed: dd_Smed_v6_38541_0_2, dd_Smed_v6_38541_0_2, [Score=47.0, Expect=2e-06]} {RNA1509_45080} {RNA1310_133134}
20. MligTC455_46046 18 0.37 Mlig455_042344

Neo: -

Age: -

 ASL 1.866 - - 0.968 - 0.898 - Mlig455_042344 {REF} {Length: 1218} {Pfam: Lyase [PF00206.22, score=41.7]; WSC domain [PF01822.21, score=31.1]} {Human: ENSG00000126522, ASL, argininosuccinate lyase, [Score=77.8, Expect=4e-16]} {Mouse: ENSMUSG00000025533, Asl, argininosuccinate lyase, [Score=76.3, Expect=8e-16]} {Dmel: FBgn0032076, CG9510, [Score=70.5, Expect=6e-14]} {Smed: dd_Smed_v6_3792_0_1, dd_Smed_v6_3792_0_1, [Score=86.7, Expect=9e-20]} {RNA1509_17568} {RNA1310_77268} {RNA815_37535}
21. MligTC455_02913 13 0.27 Mlig455_059121

Neo: -

Age: -

 1.854 - - 0.882 - 0.972 - Mlig455_059121 {REF} {Length: 1821} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=128.7]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [Score=50.1, Expect=2e-06]} {RNA1310_125080}
22. MligTC455_10153 61 1.27 Mlig455_068250, Mlig455_068270

Neo: -

Age: -

 ERBB4 1.847 - - 0.865 - 0.982 -

Mlig455_068250 {REF} {Length: 5331} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=269.3]; Protein kinase domain [PF00069.27, score=110.9]; Receptor L domain [PF01030.26, score=51.2]; Growth factor receptor domain IV [PF14843.8, score=47.2]; Furin-like cysteine rich region [PF00757.22, score=45.7]} {Human: ENSG00000178568, ERBB4, erb-b2 receptor tyrosine kinase 4, [Score=307, Expect=1e-85]; ENSG00000146648, EGFR, epidermal growth factor receptor, [Score=296, Expect=1e-82]} {Mouse: ENSMUSG00000062209, Erbb4, erb-b2 receptor tyrosine kinase 4, [Score=309, Expect=2e-86]; ENSMUSG00000020122, Egfr, epidermal growth factor receptor, [Score=295, Expect=4e-82]} {Dmel: FBgn0003731, Egfr, Epidermal growth factor receptor, [Score=311, Expect=7e-87]} {Celegans: WBGene00002299, let-23, Receptor tyrosine-protein kinase let-23, [Score=209, Expect=2e-54]} {Smed: dd_Smed_v6_11310_0_1, dd_Smed_v6_11310_0_1, [Score=303, Expect=3e-84]} {RNA1509_1271} {RNA1310_65071} {RNA815_42809}

Mlig455_068270 {REF} {Length: 5369} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=271.6]; Protein kinase domain [PF00069.27, score=111.6]} {Human: ENSG00000178568, ERBB4, erb-b2 receptor tyrosine kinase 4, [Score=303, Expect=3e-89]; ENSG00000146648, EGFR, epidermal growth factor receptor, [Score=293, Expect=7e-86]} {Mouse: ENSMUSG00000062209, Erbb4, erb-b2 receptor tyrosine kinase 4, [Score=305, Expect=4e-90]; ENSMUSG00000020122, Egfr, epidermal growth factor receptor, [Score=291, Expect=2e-85]} {Dmel: FBgn0003731, Egfr, Epidermal growth factor receptor, [Score=288, Expect=5e-84]} {Celegans: WBGene00002299, let-23, Receptor tyrosine-protein kinase let-23, [Score=207, Expect=3e-56]} {Smed: dd_Smed_v6_11310_0_1, dd_Smed_v6_11310_0_1, [Score=300, Expect=5e-88]} {RNA1509_1271} {RNA1310_65071} {RNA815_42809}
23. MligTC455_51256 668 13.92 Mlig455_015101

Neo: -

Age: -

Region-enriched R2: 12.900/0.00013
Region-enriched R3: 6.646/0.03711

Regeneration-downregulated R2: -11.444

Regeneration-depleted R2: -11.444

 1.838 - - 0.880 - 0.958 - Mlig455_015101 {REF} {Length: 702} {RNA1509_53179} {RNA1310_61610.1} {RNA815_31153}
24. MligTC455_43912 108 2.26 Mlig455_038979

Neo: -

Age: -

Region-enriched R8: 3.794/0.00970

 SNAI2 1.831 - - 0.849 - 0.982 - Mlig455_038979 {REF} {Length: 2442} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=89.3]; C2H2-type zinc finger [PF13894.8, score=57.9]; Zinc-finger double domain [PF13465.8, score=53.2]; Zinc-finger of C2H2 type [PF12874.9, score=40.2]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=40.0]; C2H2-type zinc finger [PF13912.8, score=35.8]; C2HE / C2H2 / C2HC zinc-binding finger [PF16278.7, score=24.6]; Zinc ribbon domain [PF09723.12, score=19.4]} {Human: ENSG00000019549, SNAI2, snail family transcriptional repressor 2, [RH, Score=204, Expect=3e-62]} {Mouse: ENSMUSG00000022676, Snai2, snail family zinc finger 2, [RH, Score=202, Expect=6e-62]} {Dmel: FBgn0001983, wor, worniu, [RH, Score=207, Expect=7e-61]} {Celegans: WBGene00019299, snai-1, SNAIl family zinc finger 2 transcription factor homolog, [Score=152, Expect=9e-44]} {Smed: dd_Smed_v6_10216_0_1, dd_Smed_v6_10216_0_1, [RH, Score=204, Expect=3e-62]} {RNA1509_43471} {RNA1310_64158} {RNA815_60731}
25. MligTC455_43085 7 0.14 Mlig455_035380

Neo: -

Age: -

Region-enriched R4: 3.349/0.01204

 1.83 - - 0.848 - 0.982 - Mlig455_035380 {REF} {Length: 1093} {Pfam: Lectin C-type domain [PF00059.23, score=30.6]} {RNA1509_45080} {RNA1310_133134}
26. MligTC455_53758 4602 95.88 Mlig455_016119, Mlig455_044593

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.845

Region-enriched R2: 6.352/0.00005
Region-enriched R3: 3.144/0.03322

 1.819 - - 0.860 - 0.959 -

Mlig455_016119 {REF} {Length: 484} {RNA1509_10966} {RNA1310_38782} {RNA815_8445.1}

Mlig455_044593 {REF} {Length: 718} {Pfam: ATP synthase subunit K [PF11022.10, score=19.3]} {RNA1509_10966} {RNA1310_38782} {RNA815_8445.1}
27. MligTC455_52725 54 1.13 Mlig455_043337

Neo: -

Age: Down-Up-Down

 1.813 - - 0.954 - 0.859 - Mlig455_043337 {REF} {Length: 1612} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=62.0]; Capsular polysaccharide synthesis protein [PF05704.14, score=21.9]} {Smed: dd_Smed_v6_6819_0_1, dd_Smed_v6_6819_0_1, [Score=135, Expect=4e-37]} {RNA1509_41314} {RNA1310_23090.1, RNA1509_41314} {RNA1509_41314, RNA815_9794.1}
28. MligTC455_34232 35 0.73 Mlig455_051899

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.310

Region-enriched R3: 6.749/0.02565

 ACR 1.799 - - 0.963 - 0.836 - Mlig455_051899 {REF} {Length: 1242} {Pfam: Trypsin [PF00089.28, score=169.8]} {Human: ENSG00000100312, ACR, acrosin, [Score=154, Expect=5e-43]; ENSG00000283539, ACR, acrosin, [Score=154, Expect=5e-43]; ENSG00000198670, LPA, lipoprotein(a), [Score=152, Expect=3e-40]; ENSG00000122194, PLG, plasminogen, [Score=152, Expect=1e-40]; ENSG00000178297, TMPRSS9, transmembrane serine protease 9, [Score=148, Expect=5e-39]; ENSG00000103355, PRSS33, serine protease 33, [Score=148, Expect=5e-42]} {Mouse: ENSMUSG00000059481, Plg, plasminogen, [Score=150, Expect=5e-40]; ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=148, Expect=2e-39]; ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [Score=144, Expect=6e-38]} {Dmel: FBgn0036287, CG10663, [Score=129, Expect=8e-33]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [Score=122, Expect=2e-32]} {Smed: dd_Smed_v6_2492_0_1, dd_Smed_v6_2492_0_1, [Score=172, Expect=4e-51]} {RNA1509_37786} {RNA1310_26421} {RNA815_13601}
29. MligTC455_31240 329 6.85 Mlig455_010150

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.167

Region-enriched R4: 6.247/0.01251

 1.795 - - 0.827 - 0.968 - Mlig455_010150 {REF} {Length: 557} {RNA1509_16524, RNA1509_26056} {RNA1310_74791.1, RNA1509_16524} {RNA1509_16524, RNA815_37646}
30. MligTC455_51029 340 7.09 Mlig455_056736

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.541

 1.794 - - 0.839 - 0.955 - Mlig455_056736 {REF} {Length: 850} {RNA1509_4527} {RNA1310_27536} {RNA815_19650}
31. MligTC455_16837 11 0.24 Mlig455_030150

Neo: -

Age: -

 1.786 - - 0.802 - 0.984 - Mlig455_030150 {REF} {Length: 1228} {RNA1310_40798} {RNA815_26160}
32. MligTC455_20532 63 1.32 Mlig455_029971

Neo: -

Age: -

 1.786 - - 0.828 - 0.958 - Mlig455_029971 {REF} {Length: 1702} {Pfam: UPF0489 domain [PF12640.9, score=20.3]} {RNA1509_3030} {RNA1310_35103} {RNA815_26539}
33. MligTC455_33538 789 16.45 Mlig455_051129, Mlig455_051205

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.262

Region-specific R2: 4.638

Region-enriched R2: 3.952/0.00052

 LRRIQ4 1.785 - - 0.957 - 0.828 -

Mlig455_051129 {REF} {Length: 1662} {Pfam: Leucine rich repeat [PF13855.8, score=77.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=61.4]} {Human: ENSG00000188306, LRRIQ4, leucine rich repeats and IQ motif containing 4, [Score=95.5, Expect=6e-21]; ENSG00000240720, LRRD1, leucine rich repeats and death domain containing 1, [Score=93.6, Expect=4e-20]; ENSG00000130224, LRCH2, leucine rich repeats and calponin homology domain containing 2, [Score=93.2, Expect=4e-20]; ENSG00000163827, LRRC2, leucine rich repeat containing 2, [Score=92.4, Expect=2e-20]; ENSG00000033122, LRRC7, leucine rich repeat containing 7, [Score=91.7, Expect=2e-19]} {Mouse: ENSMUSG00000070056, Mfhas1, malignant fibrous histiocytoma amplified sequence 1, [Score=115, Expect=9e-28]} {Dmel: FBgn0033984, Lap1, [Score=86.3, Expect=4e-18]} {Celegans: WBGene00002632, let-413, [Score=90.5, Expect=1e-19]} {Smed: dd_Smed_v6_17742_0_1, dd_Smed_v6_17742_0_1, [RH, Score=360, Expect=1e-124]} {RNA1509_30762} {RNA1310_31301} {RNA815_15435}

Mlig455_051205 {REF} {Length: 2514} {Pfam: Leucine rich repeat [PF13855.8, score=72.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=59.1]} {Human: ENSG00000188306, LRRIQ4, leucine rich repeats and IQ motif containing 4, [Score=94.7, Expect=1e-20]; ENSG00000130224, LRCH2, leucine rich repeats and calponin homology domain containing 2, [Score=93.2, Expect=4e-20]; ENSG00000240720, LRRD1, leucine rich repeats and death domain containing 1, [Score=92.8, Expect=6e-20]; ENSG00000163827, LRRC2, leucine rich repeat containing 2, [Score=92.4, Expect=2e-20]; ENSG00000033122, LRRC7, leucine rich repeat containing 7, [Score=91.3, Expect=3e-19]} {Mouse: ENSMUSG00000070056, Mfhas1, malignant fibrous histiocytoma amplified sequence 1, [Score=115, Expect=1e-27]} {Dmel: FBgn0033984, Lap1, [Score=85.5, Expect=9e-18]} {Celegans: WBGene00002632, let-413, [Score=90.5, Expect=1e-19]} {Smed: dd_Smed_v6_17742_0_1, dd_Smed_v6_17742_0_1, [RH, Score=362, Expect=2e-125]} {RNA1509_30762} {RNA1310_31301, RNA1509_30762} {RNA1509_30762, RNA815_15435}
34. MligTC455_33877 47 0.97 Mlig455_053914

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.540

 PKD1L2 1.784 - - 0.802 - 0.982 - Mlig455_053914 {REF} {Length: 11153} {Pfam: Polycystin cation channel [PF08016.14, score=263.3]; PKD domain [PF18911.2, score=78.1]; PLAT/LH2 domain [PF01477.25, score=77.6]; PKD domain [PF00801.22, score=77.5]; REJ domain [PF02010.17, score=51.1]; Ion transport protein [PF00520.33, score=32.5]} {Human: ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [Score=236, Expect=4e-61]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=254, Expect=1e-66]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=132, Expect=3e-30]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=134, Expect=1e-30]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=451, Expect=4e-127]} {RNA1509_40400} {RNA1310_23183} {RNA815_27645}
35. MligTC455_48791 22 0.45 Mlig455_049838

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.709

 1.763 - - 0.963 - 0.800 - Mlig455_049838 {REF} {Length: 1309} {RNA1509_59166} {RNA1310_26794.1} {RNA815_13204}
36. MligTC455_13408 50 1.05 Mlig455_023158, Mlig455_023242

Neo: -

Age: -

 LRRC45 1.751 - - 0.792 - 0.959 -

Mlig455_023158 {REF} {Length: 4137} {Pfam: Leucine Rich repeat [PF13516.8, score=28.4]; Protein of unknown function (DUF465) [PF04325.15, score=18.7]} {Human: ENSG00000169683, LRRC45, leucine rich repeat containing 45, [Score=259, Expect=3e-77]} {Mouse: ENSMUSG00000025145, Lrrc45, leucine rich repeat containing 45, [Score=256, Expect=3e-76]} {Smed: dd_Smed_v6_9495_0_1, dd_Smed_v6_9495_0_1, [Score=266, Expect=6e-80]} {RNA1509_9663} {RNA1310_9890.1} {RNA815_3417}

Mlig455_023242 {REF} {Length: 1433} {Pfam: Leucine Rich repeat [PF13516.8, score=28.4]; Protein of unknown function (DUF465) [PF04325.15, score=18.7]} {Human: ENSG00000169683, LRRC45, leucine rich repeat containing 45, [Score=259, Expect=3e-77]} {Mouse: ENSMUSG00000025145, Lrrc45, leucine rich repeat containing 45, [Score=256, Expect=3e-76]} {Smed: dd_Smed_v6_9495_0_1, dd_Smed_v6_9495_0_1, [Score=266, Expect=6e-80]} {RNA1509_9663} {RNA1310_9890.1} {RNA815_3417}
37. MligTC455_23857 179 3.73 Mlig455_011373

Neo: -

Age: -

 KCNN2 1.729 - - 0.760 - 0.969 - Mlig455_011373 {REF} {Length: 4119} {Pfam: Calcium-activated SK potassium channel [PF03530.16, score=144.8]; Calmodulin binding domain [PF02888.18, score=112.8]; Ion channel [PF07885.18, score=51.5]} {Human: ENSG00000080709, KCNN2, potassium calcium-activated channel subfamily N member 2, [RH, Score=541, Expect=4e-180]; ENSG00000143603, KCNN3, potassium calcium-activated channel subfamily N member 3, [RH, Score=534, Expect=5e-179]; ENSG00000105642, KCNN1, potassium calcium-activated channel subfamily N member 1, [RH, Score=514, Expect=4e-174]} {Mouse: ENSMUSG00000054477, Kcnn2, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2, [RH, Score=543, Expect=0.0]; ENSMUSG00000000794, Kcnn3, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3, [RH, Score=533, Expect=7e-179]} {Dmel: FBgn0029761, SK, small conductance calcium-activated potassium channel, [RH, Score=602, Expect=0.0]} {Celegans: WBGene00008570, kcnl-2, KCNL-2 variant; KCNN (Potassium K ChaNNel, calcium activated)-Like, [RH, Score=428, Expect=5e-137]} {Smed: dd_Smed_v6_14006_0_1, dd_Smed_v6_14006_0_1, [RH, Score=552, Expect=0.0]} {RNA1509_39011, RNA1509_39273} {RNA1310_12409, RNA1509_39011, RNA1509_39273} {RNA1509_39011, RNA1509_39273, RNA815_5551}
38. MligTC455_26419 3 0.07 Mlig455_057242

Neo: -

Age: -

 TRPM3 0.996 - - - - 0.996 - Mlig455_057242 {REF} {Length: 3957} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=50.3]; Ankyrin repeats (many copies) [PF13637.8, score=37.2]; Ankyrin repeat [PF13606.8, score=25.6]; Ankyrin repeats (many copies) [PF13857.8, score=22.7]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=70.5, Expect=2e-11]; ENSG00000274965, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=69.7, Expect=3e-11]; ENSG00000134160, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=69.3, Expect=4e-11]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=71.6, Expect=6e-12]; ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [Score=70.5, Expect=1e-11]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=80.1, Expect=9e-15]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=62.4, Expect=2e-09]} {Smed: dd_Smed_v6_11259_0_12, dd_Smed_v6_11259_0_12, [Score=90.1, Expect=4e-18]} {RNA1509_29189} {RNA1310_64091} {RNA815_42967}
39. MligTC455_46657 38 0.78 Mlig455_012068

Neo: -

Age: -

 TPCN2 0.995 - - - - 0.995 - Mlig455_012068 {REF} {Length: 3085} {TRANSSPLICED} {Pfam: Ion transport protein [PF00520.33, score=73.6]} {Human: ENSG00000162341, TPCN2, two pore segment channel 2, [Score=74.3, Expect=4e-14]} {Mouse: ENSMUSG00000048677, Tpcn2, two pore segment channel 2, [Score=77.0, Expect=3e-15]} {Smed: dd_Smed_v6_8333_0_1, dd_Smed_v6_8333_0_1, [Score=95.5, Expect=1e-21]} {RNA1509_51248} {RNA1310_6971.1} {RNA815_23671}
40. MligTC455_45761 2 0.04 Mlig455_069954

Neo: -

Age: -

 0.994 - - - - 0.994 - Mlig455_069954 {REF} {Length: 1707} {NoTransDecoderORF} {RNA1310_147977} {RNA815_46078}
41. MligTC455_07145 4 0.08 Mlig455_019416

Neo: -

Age: -

 0.993 - - - - 0.993 - Mlig455_019416 {REF} {Length: 953} {NoTransDecoderORF} {RNA1509_45595} {RNA1310_6806} {RNA815_7856.1}
42. MligTC455_21462 18 0.38 Mlig455_013221

Neo: -

Age: -

 0.993 - - - - 0.993 - Mlig455_013221 {REF} {Length: 1150} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_38412} {RNA1310_33160.1} {RNA815_51877}
43. MligTC455_08208 16 0.34 Mlig455_060343

Neo: -

Age: -

 0.992 - - - - 0.992 - Mlig455_060343 {REF} {Length: 392} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_52997} {RNA1310_51420} {RNA815_20481.2}
44. MligTC455_10688 2 0.05 Mlig455_046122

Neo: -

Age: -

 0.992 - - - - 0.992 - Mlig455_046122 {REF} {Length: 278} {NoTransDecoderORF}
45. MligTC455_10898 23 0.48 Mlig455_042130

Neo: -

Age: -

 0.992 - - - - 0.992 - Mlig455_042130 {REF} {Length: 1395} {Pfam: F5/8 type C domain [PF00754.27, score=27.1]; PAN domain [PF00024.28, score=18.5]} {RNA1310_31572} {RNA815_19460}
46. MligTC455_30579 3 0.07 Mlig455_062783

Neo: -

Age: Down-Up-Up

 0.992 - - - - 0.992 - Mlig455_062783 {REF} {Length: 2008} {Celegans: WBGene00015646, mlt-10, [Score=171, Expect=5e-45]} {RNA1509_25856} {RNA1310_22909} {RNA815_18032}
47. MligTC455_52568 15 0.32 Mlig455_018332

Neo: -

Age: -

 0.992 - - - - 0.992 - Mlig455_018332 {REF} {Length: 784}
48. MligTC455_56932 1 0.03 Mlig455_071056

Neo: -

Age: -

 0.992 - - - - 0.992 - Mlig455_071056 {REF} {Length: 126} {NoTransDecoderORF} {RNA1310_39216.1}
49. MligTC455_05848 1 0.03 Mlig455_034834

Neo: -

Age: -

 0.991 - - - - 0.991 - Mlig455_034834 {REF} {Length: 247} {NoTransDecoderORF}
50. MligTC455_15841 197 4.09 Mlig455_045803, Mlig455_063182

Neo: -

Age: -

 0.991 - - - - 0.991 -

Mlig455_045803 {REF} {Length: 763} {RNA1310_103953} {RNA815_42645}

Mlig455_063182 {REF} {Length: 773} {RNA1310_103953} {RNA815_42645}
51. MligTC455_12562 1 0.02 Mlig455_033005

Neo: -

Age: -

 0.989 - - - - 0.989 - Mlig455_033005 {REF} {Length: 736} {NoTransDecoderORF} {RNA1310_53457} {RNA815_45760}
52. MligTC455_21668 84 1.74 Mlig455_024837

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.324

 PPP3R1 0.988 - - 0.988 - - - Mlig455_024837 {REF} {Length: 1650} {Pfam: EF hand [PF00036.34, score=92.6]; EF-hand domain pair [PF13499.8, score=86.6]; EF-hand domain [PF13405.8, score=74.3]; EF hand [PF13202.8, score=72.6]; EF-hand domain pair [PF13833.8, score=65.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=30.2]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=27.0]; EF-hand domain [PF14658.8, score=21.7]} {Human: ENSG00000221823, PPP3R1, protein phosphatase 3 regulatory subunit B, alpha, [RH, Score=289, Expect=5e-101]} {Mouse: ENSMUSG00000033953, Ppp3r1, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I), [RH, Score=289, Expect=3e-101]} {Dmel: FBgn0010014, CanB, Calcineurin B, [RH, Score=282, Expect=1e-98]} {Celegans: WBGene00000554, cnb-1, Protein phosphatase 2B regulatory subunit cnb-1, [RH, Score=272, Expect=7e-95]} {Smed: dd_Smed_v6_5589_0_1, dd_Smed_v6_5589_0_1, [RH, Score=281, Expect=1e-98]} {RNA1509_14613} {RNA1310_16848.1} {RNA815_6272}
53. MligTC455_09020 15 0.32 Mlig455_000455

Neo: -

Age: -

 0.986 - - - - 0.986 - Mlig455_000455 {REF} {Length: 1010} {NoTransDecoderORF}
54. MligTC455_09328 39 0.8 Mlig455_032045

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.716

 0.986 - - - - 0.986 - Mlig455_032045 {REF} {Length: 2583} {Pfam: Domain of unknown function (DUF4010) [PF13194.8, score=20.4]} {RNA1310_46777} {RNA815_42352}
55. MligTC455_11788 20 0.41 Mlig455_043729, Mlig455_043819, Mlig455_047429

Neo: -

Age: -

 ANGPTL1 0.986 - - - - 0.986 -

Mlig455_043729 {REF} {Length: 1137} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=144.4]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=131, Expect=2e-34]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=129, Expect=9e-34]; ENSG00000130812, ANGPTL6, angiopoietin like 6, [Score=127, Expect=5e-33]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=134, Expect=9e-36]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=131, Expect=8e-35]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=129, Expect=8e-34]} {Dmel: FBgn0003326, sca, scabrous, [Score=119, Expect=4e-30]} {Celegans: WBGene00017013, ensh-1, [Score=46.6, Expect=1e-05]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=110, Expect=4e-27]} {RNA1509_26827} {RNA1310_41424} {RNA815_48855}

Mlig455_043819 {REF} {Length: 1111} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=143.1]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=129, Expect=1e-33]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=127, Expect=4e-33]; ENSG00000130812, ANGPTL6, angiopoietin like 6, [Score=125, Expect=2e-32]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=132, Expect=5e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=130, Expect=3e-34]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=127, Expect=4e-33]} {Dmel: FBgn0003326, sca, scabrous, [Score=117, Expect=2e-29]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=108, Expect=2e-26]} {RNA1509_26827} {RNA1310_41424} {RNA815_48855}

Mlig455_047429 {REF} {Length: 1072} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=143.1]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=129, Expect=1e-33]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=127, Expect=4e-33]; ENSG00000130812, ANGPTL6, angiopoietin like 6, [Score=125, Expect=2e-32]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=132, Expect=5e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=130, Expect=3e-34]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=127, Expect=4e-33]} {Dmel: FBgn0003326, sca, scabrous, [Score=117, Expect=2e-29]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=108, Expect=2e-26]} {RNA1509_26827} {RNA1310_41424} {RNA815_48855}
56. MligTC455_18332 14 0.28 Mlig455_029709

Neo: -

Age: -

 FOXD4 0.986 - - - - 0.986 - Mlig455_029709 {REF} {Length: 1306} {Pfam: Forkhead domain [PF00250.20, score=129.2]} {Human: ENSG00000170122, FOXD4, forkhead box D4, [RH, Score=189, Expect=1e-56]} {Mouse: ENSMUSG00000067261, Foxd3, forkhead box D3, [Score=182, Expect=4e-54]; ENSMUSG00000116152, Foxd3, forkhead box D3, [Score=182, Expect=4e-54]; ENSMUSG00000078302, Foxd1, forkhead box D1, [Score=174, Expect=6e-51]} {Dmel: FBgn0004896, fd59A, forkhead domain 59A, [RH, Score=202, Expect=7e-62]} {Celegans: WBGene00006853, unc-130, [Score=190, Expect=1e-58]} {Smed: dd_Smed_v6_23249_0_1, dd_Smed_v6_23249_0_1, [Score=203, Expect=1e-62]} {RNA1310_78891}
57. MligTC455_52507 60 1.26 Mlig455_016440

Neo: -

Age: -

Region-enriched R2: 5.871/0.01204

 0.986 - - 0.986 - - - Mlig455_016440 {REF} {Length: 1576} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1310_98267}
58. MligTC455_12683 4 0.08 Mlig455_013681

Neo: -

Age: -

 CASKIN1 0.984 - - - - 0.984 - Mlig455_013681 {REF} {Length: 1211} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=125.4]; Ankyrin repeats (many copies) [PF13637.8, score=124.7]; Ankyrin repeat [PF00023.32, score=101.7]; Ankyrin repeats (many copies) [PF13857.8, score=98.5]; Ankyrin repeat [PF13606.8, score=97.6]} {Human: ENSG00000167971, CASKIN1, CASK interacting protein 1, [Score=174, Expect=4e-47]; ENSG00000177303, CASKIN2, CASK interacting protein 2, [Score=172, Expect=2e-46]} {Mouse: ENSMUSG00000033597, Caskin1, CASK interacting protein 1, [Score=174, Expect=2e-47]; ENSMUSG00000034471, Caskin2, CASK-interacting protein 2, [Score=169, Expect=1e-45]} {Dmel: FBgn0039075, CG4393, [Score=122, Expect=1e-29]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=102, Expect=4e-23]} {Smed: dd_Smed_v6_2072_0_26, dd_Smed_v6_2072_0_26, [Score=110, Expect=4e-26]} {RNA1310_1281}
59. MligTC455_33878 51 1.06 Mlig455_060557

Neo: -

Age: Up-Down-Down

 PKD1L1 0.984 - - - - 0.984 - Mlig455_060557 {REF} {Length: 10235} {Pfam: Polycystin cation channel [PF08016.14, score=213.7]; PLAT/LH2 domain [PF01477.25, score=42.6]} {Human: ENSG00000158683, PKD1L1, polycystin 1 like 1, transient receptor potential channel interacting, [Score=161, Expect=2e-39]; ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [Score=157, Expect=2e-38]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=195, Expect=3e-50]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=89.0, Expect=1e-17]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=117, Expect=7e-27]} {Smed: dd_Smed_v6_15525_0_1, dd_Smed_v6_15525_0_1, [Score=306, Expect=9e-87]} {RNA1509_40400} {RNA1310_24325} {RNA815_27769}
60. MligTC455_45246 18 0.38 Mlig455_011863

Neo: -

Age: -

 NLK 0.984 - - - - 0.984 - Mlig455_011863 {REF} {Length: 5776} {Pfam: Protein kinase domain [PF00069.27, score=208.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=94.9]; ABC1 atypical kinase-like domain [PF03109.18, score=19.9]; Fungal protein kinase [PF17667.3, score=19.4]} {Human: ENSG00000087095, NLK, nemo like kinase, [RH, Score=444, Expect=1e-150]} {Mouse: ENSMUSG00000017376, Nlk, nemo like kinase, [RH, Score=444, Expect=7e-151]} {Dmel: FBgn0011817, nmo, nemo, [RH, Score=450, Expect=1e-154]} {Celegans: WBGene00003048, lit-1, Serine/threonine kinase NLK, [RH, Score=394, Expect=9e-130]} {Smed: dd_Smed_v6_4172_0_3, dd_Smed_v6_4172_0_3, [RH, Score=431, Expect=1e-146]} {RNA1509_6933} {RNA1310_7196.1} {RNA815_3487.2}
61. MligTC455_29264 78 1.62 Mlig455_061707

Neo: -

Age: logFC(26M/2M)=1.238

 0.983 - - 0.983 - - - Mlig455_061707 {REF} {Length: 5671} {Pfam: Zinc knuckle [PF00098.25, score=33.9]} {Celegans: WBGene00017210, F07E5.5, [Score=53.5, Expect=3e-07]} {RNA1509_12781} {RNA1310_541.1} {RNA815_23.1}
62. MligTC455_00360 3 0.06 Mlig455_003350

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_003350 {REF} {Length: 572} {NoTransDecoderORF} {RNA1509_37106} {RNA1310_20119} {RNA815_32661}
63. MligTC455_00893 1 0.02 Mlig455_044599

Neo: -

Age: -

 CUBN 0.982 - - - - 0.982 - Mlig455_044599 {REF} {Length: 872} {Pfam: CUB domain [PF00431.22, score=55.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=58.2, Expect=3e-09]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=53.1, Expect=9e-08]} {Smed: dd_Smed_v6_69474_0_1, dd_Smed_v6_69474_0_1, [Score=44.3, Expect=3e-06]} {RNA1310_66805}
64. MligTC455_01855 5 0.1 Mlig455_019884

Neo: Germline

Age: -

 0.982 - - - - 0.982 - Mlig455_019884 {REF} {Length: 837} {RNA1310_46030.1} {RNA815_34666}
65. MligTC455_01972 8 0.17 Mlig455_065411

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_065411 {REF} {Length: 646} {RNA1310_149608}
66. MligTC455_02383 3 0.07 Mlig455_006775

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_006775 {REF} {Length: 1124} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=95.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=86.3]; Aspartyl protease [PF13650.8, score=20.6]; gag-polyprotein putative aspartyl protease [PF13975.8, score=19.6]} {Smed: dd_Smed_v6_15498_0_18, dd_Smed_v6_15498_0_18, [Score=79.3, Expect=2e-16]} {RNA1509_44038} {RNA1310_11212} {RNA815_45036}
67. MligTC455_03210 1 0.02 Mlig455_026190

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_026190 {REF} {Length: 673} {NoTransDecoderORF}
68. MligTC455_03483 14 0.29 Mlig455_004066, Mlig455_004118, Mlig455_060442

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.509

 0.982 - - - - 0.982 -

Mlig455_004066 {REF} {Length: 399} {NoTransDecoderORF} {RNA1509_9966} {RNA1310_27634} {RNA815_4490.1}

Mlig455_004118 {REF} {Length: 567} {NoTransDecoderORF} {RNA1509_9966} {RNA1310_12692.1} {RNA815_4490.1}

Mlig455_060442 {REF} {Length: 536} {NoTransDecoderORF} {RNA1509_9966} {RNA1310_12692.1} {RNA815_4490.1}
69. MligTC455_04465 2 0.04 Mlig455_019145

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_019145 {REF} {Length: 352} {NoTransDecoderORF} {RNA1310_89330}
70. MligTC455_04679 2 0.04 Mlig455_058054

Neo: -

Age: Up-Down-Down

 0.982 - - - - 0.982 - Mlig455_058054 {REF} {Length: 1496} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=50.2]} {Smed: dd_Smed_v6_9783_0_1, dd_Smed_v6_9783_0_1, [Score=92.4, Expect=1e-20]} {RNA1509_4484} {RNA1310_25467} {RNA815_39314}
71. MligTC455_05305 1 0.03 Mlig455_021332

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_021332 {REF} {Length: 354} {NoTransDecoderORF}
72. MligTC455_05413 5 0.1 Mlig455_009332

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_009332 {REF} {Length: 473} {NoTransDecoderORF} {RNA1509_17823} {RNA1310_43999} {RNA815_18130}
73. MligTC455_05756 6 0.12 Mlig455_005000

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_005000 {REF} {Length: 299} {NoTransDecoderORF} {RNA1310_141322}
74. MligTC455_05804 5 0.11 Mlig455_012115

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_012115 {REF} {Length: 533} {NoTransDecoderORF} {RNA1310_54712.2} {RNA815_20004.2}
75. MligTC455_05866 26 0.54 Mlig455_003192, Mlig455_026798

Neo: -

Age: -

Region-enriched R4: 5.964/0.03025

 0.982 - - - - 0.982 -

Mlig455_003192 {REF} {Length: 393} {NoTransDecoderORF} {RNA1509_44471} {RNA1310_75127.2} {RNA815_51525}

Mlig455_026798 {REF} {Length: 556} {NoTransDecoderORF} {RNA1310_75127.2} {RNA815_51525}
76. MligTC455_06143 5 0.11 Mlig455_064395

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_064395 {REF} {Length: 727} {RNA1509_58025} {RNA1310_20554} {RNA815_7470.1}
77. MligTC455_06604 25 0.52 Mlig455_020786

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.598

 KREMEN1 0.982 - - - - 0.982 - Mlig455_020786 {REF} {Length: 1762} {Pfam: WSC domain [PF01822.21, score=65.2]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=56.2, Expect=3e-09]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=58.5, Expect=3e-10]} {RNA1509_36914, RNA1509_47848} {RNA1310_9932.1, RNA1509_47848} {RNA1509_47848, RNA815_31064}
78. MligTC455_06679 3 0.07 Mlig455_051102

Neo: -

Age: -

 SLC7A1 0.982 - - - - 0.982 - Mlig455_051102 {REF} {Length: 1849} {Pfam: Amino acid permease [PF13520.8, score=121.8]; Amino acid permease [PF00324.23, score=104.4]; C-terminus of AA_permease [PF13906.8, score=56.3]} {Human: ENSG00000139514, SLC7A1, solute carrier family 7 member 1, [Score=289, Expect=3e-89]; ENSG00000003989, SLC7A2, solute carrier family 7 member 2, [Score=280, Expect=1e-85]; ENSG00000099960, SLC7A4, solute carrier family 7 member 4, [Score=278, Expect=5e-85]} {Mouse: ENSMUSG00000022756, Slc7a4, solute carrier family 7 (cationic amino acid transporter, y+ system), member 4, [Score=294, Expect=4e-91]; ENSMUSG00000041313, Slc7a1, solute carrier family 7 (cationic amino acid transporter, y+ system), member 1, [Score=292, Expect=2e-90]; ENSMUSG00000054753, AU018091, expressed sequence AU018091, [Score=288, Expect=1e-88]; ENSMUSG00000107871, AU018091, expressed sequence AU018091, [Score=288, Expect=1e-88]} {Dmel: FBgn0036984, CG13248, [Score=296, Expect=1e-91]} {Celegans: WBGene00016806, C50D2.2, [Score=296, Expect=1e-92]} {Smed: dd_Smed_v6_8652_0_8, dd_Smed_v6_8652_0_8, [Score=436, Expect=3e-147]} {RNA1310_82370} {RNA815_51664}
79. MligTC455_06723 4 0.09 Mlig455_029808, Mlig455_034904

Neo: -

Age: -

 ARHGAP39 0.982 - - - - 0.982 -

Mlig455_029808 {REF} {Length: 738} {Pfam: WW domain [PF00397.28, score=28.3]} {Human: ENSG00000147799, ARHGAP39, Rho GTPase activating protein 39, [Score=94.7, Expect=4e-22]} {Mouse: ENSMUSG00000033697, Arhgap39, Rho GTPase activating protein 39, [RH, Score=92.0, Expect=1e-23]} {Dmel: FBgn0038853, RhoGAP93B, Rho GTPase activating protein at 93B, [Score=92.4, Expect=1e-21]} {Celegans: WBGene00022367, Y92H12BM.1, [Score=90.9, Expect=2e-22]} {Smed: dd_Smed_v6_5836_0_1, dd_Smed_v6_5836_0_1, [Score=65.1, Expect=2e-12]} {RNA1310_92124} {RNA815_58680}

Mlig455_034904 {REF} {Length: 707} {Pfam: WW domain [PF00397.28, score=28.9]} {Human: ENSG00000147799, ARHGAP39, Rho GTPase activating protein 39, [Score=94.0, Expect=4e-22]} {Mouse: ENSMUSG00000033697, Arhgap39, Rho GTPase activating protein 39, [RH, Score=91.7, Expect=6e-24]} {Dmel: FBgn0038853, RhoGAP93B, Rho GTPase activating protein at 93B, [Score=92.4, Expect=8e-22]} {Celegans: WBGene00022367, Y92H12BM.1, [Score=90.9, Expect=1e-22]} {Smed: dd_Smed_v6_5836_0_1, dd_Smed_v6_5836_0_1, [Score=65.1, Expect=1e-12]} {RNA1310_92124} {RNA815_58680}
80. MligTC455_06894 6 0.12 Mlig455_032458

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_032458 {REF} {Length: 2789} {RNA1509_57110} {RNA1310_20410, RNA1509_57110} {RNA1509_57110, RNA815_19103}
81. MligTC455_07515 13 0.27 Mlig455_048357

Neo: -

Age: -

 HCRTR1 0.982 - - - - 0.982 - Mlig455_048357 {REF} {Length: 1740} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=51.8]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=38.9]} {Human: ENSG00000121764, HCRTR1, hypocretin receptor 1, [Score=49.7, Expect=6e-06]} {Mouse: ENSMUSG00000028778, Hcrtr1, hypocretin (orexin) receptor 1, [Score=49.7, Expect=4e-06]} {Dmel: FBgn0029723, Proc-R, Proctolin receptor, [Score=52.0, Expect=5e-07]} {Smed: dd_Smed_v6_27761_0_1, dd_Smed_v6_27761_0_1, [Score=103, Expect=3e-24]} {RNA1509_33416} {RNA1310_68701}
82. MligTC455_08857 29 0.61 Mlig455_009086

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_009086 {REF} {Length: 561} {RNA1310_27547} {RNA815_16487}
83. MligTC455_09359 17 0.35 Mlig455_059675

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_059675 {REF} {Length: 522} {NoTransDecoderORF} {RNA1310_149181}
84. MligTC455_09474 3 0.05 Mlig455_007677

Neo: -

Age: -

 C1GALT1 0.982 - - - - 0.982 - Mlig455_007677 {REF} {Length: 1547} {Pfam: Galactosyltransferase [PF01762.23, score=27.6]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=161, Expect=2e-46]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=162, Expect=7e-47]} {Dmel: FBgn0032078, C1GalTA, Core 1 Galactosyltransferase A, [Score=139, Expect=6e-38]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=165, Expect=4e-48]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=186, Expect=3e-56]} {RNA1310_125941}
85. MligTC455_09527 9 0.19 Mlig455_003833

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_003833 {REF} {Length: 456} {RNA1310_99936} {RNA815_40952}
86. MligTC455_10341 15 0.32 Mlig455_012927

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_012927 {REF} {Length: 697} {RNA1509_52329} {RNA1310_58743.2} {RNA815_30339}
87. MligTC455_10487 2 0.04 Mlig455_014098

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_014098 {REF} {Length: 160} {NoTransDecoderORF} {RNA1310_83952}
88. MligTC455_10618 9 0.18 Mlig455_070725

Neo: -

Age: -

 ZNF20 0.982 - - - - 0.982 - Mlig455_070725 {REF} {Length: 1704} {Pfam: Zinc-finger double domain [PF13465.8, score=36.3]; Zinc finger, C2H2 type [PF00096.28, score=25.2]; C2H2-type zinc finger [PF13894.8, score=20.1]} {Human: ENSG00000132010, ZNF20, zinc finger protein 20, [Score=67.8, Expect=5e-12]; ENSG00000144026, ZNF514, zinc finger protein 514, [Score=65.9, Expect=2e-11]; ENSG00000136866, ZFP37, ZFP37 zinc finger protein, [Score=65.9, Expect=3e-11]; ENSG00000102974, CTCF, CCCTC-binding factor, [Score=65.5, Expect=4e-11]} {Mouse: ENSMUSG00000102030, Gm29106, predicted gene 29106, [Score=70.1, Expect=8e-13]} {Dmel: FBgn0003567, su(Hw), suppressor of Hairy wing, [Score=64.7, Expect=3e-11]} {Celegans: WBGene00006492, let-391, [Score=63.2, Expect=6e-11]} {Smed: dd_Smed_v6_15745_0_1, dd_Smed_v6_15745_0_1, [RH, Score=122, Expect=8e-34]} {RNA1310_53462}
89. MligTC455_11102 4 0.08 Mlig455_058382

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_058382 {REF} {Length: 696}
90. MligTC455_11286 3 0.06 Mlig455_034416

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_034416 {REF} {Length: 1654} {NoTransDecoderORF} {RNA1310_86650} {RNA815_19306}
91. MligTC455_11354 2 0.05 Mlig455_018374

Neo: -

Age: -

 AC079594.2 0.982 - - - - 0.982 - Mlig455_018374 {REF} {Length: 2356} {Pfam: RING-type zinc-finger [PF13445.8, score=36.5]; Ring finger domain [PF13639.8, score=36.0]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=34.7]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=34.0]; zinc finger of C3HC4-type, RING [PF15227.8, score=32.4]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=32.2]; zinc-RING finger domain [PF14634.8, score=27.2]; RING-H2 zinc finger domain [PF12678.9, score=22.1]; RING/Ubox like zinc-binding domain [PF14570.8, score=20.5]} {Human: ENSG00000248710, AC079594.2, novel tripartite motif-containing 59 (TRIM59) and intraflagellar transport 80 homolog (Chlamydomonas) (IFT80) protein, [Score=59.7, Expect=5e-09]; ENSG00000156463, SH3RF2, SH3 domain containing ring finger 2, [Score=59.7, Expect=4e-09]; ENSG00000213186, TRIM59, tripartite motif containing 59, [Score=57.4, Expect=9e-10]} {Mouse: ENSMUSG00000057719, Sh3rf2, SH3 domain containing ring finger 2, [Score=63.2, Expect=3e-10]} {Dmel: FBgn0040294, POSH, Plenty of SH3s, [Score=53.9, Expect=2e-07]} {Celegans: WBGene00003597, nhl-1, RING finger protein nhl-1, [Score=48.9, Expect=4e-06]} {Smed: dd_Smed_v6_6290_0_1, dd_Smed_v6_6290_0_1, [Score=48.5, Expect=4e-06]} {RNA1310_52131} {RNA815_43681}
92. MligTC455_11377 4 0.09 Mlig455_022382

Neo: -

Age: -

 KREMEN2 0.982 - - - - 0.982 - Mlig455_022382 {REF} {Length: 838} {Pfam: WSC domain [PF01822.21, score=47.5]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.4, Expect=2e-07]; ENSG00000075035, WSCD2, WSC domain containing 2, [Score=50.8, Expect=6e-07]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=54.3, Expect=3e-08]; ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=53.1, Expect=6e-08]} {RNA1310_112537} {RNA815_23500}
93. MligTC455_11537 2 0.05 Mlig455_041467

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_041467 {REF} {Length: 326}
94. MligTC455_11755 5 0.11 Mlig455_018946

Neo: -

Age: -

 GRM5 0.982 - - - - 0.982 - Mlig455_018946 {REF} {Length: 1559} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=93.6]; Nine Cysteines Domain of family 3 GPCR [PF07562.16, score=41.7]} {Human: ENSG00000168959, GRM5, glutamate metabotropic receptor 5, [Score=143, Expect=3e-36]} {Mouse: ENSMUSG00000049583, Grm5, glutamate receptor, metabotropic 5, [Score=140, Expect=2e-35]} {Dmel: FBgn0019985, mGluR, metabotropic Glutamate Receptor, [Score=131, Expect=1e-32]} {Celegans: WBGene00021152, mgl-3, Metabotropic GLutamate receptor family, [Score=98.6, Expect=6e-22]} {Smed: dd_Smed_v6_15419_0_1, dd_Smed_v6_15419_0_1, [Score=123, Expect=4e-30]} {RNA1310_98186}
95. MligTC455_11934 8 0.16 Mlig455_008593, Mlig455_008607

Neo: -

Age: -

 GALR2 0.982 - - - - 0.982 -

Mlig455_008593 {REF} {Length: 1678} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=148.1]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=26.6]; Serpentine type 7TM GPCR chemoreceptor Sru [PF10322.11, score=19.9]} {Human: ENSG00000182687, GALR2, galanin receptor 2, [Score=145, Expect=3e-39]} {Mouse: ENSMUSG00000020793, Galr2, galanin receptor 2, [Score=136, Expect=4e-36]} {Dmel: FBgn0036789, AstC-R2, Allatostatin C receptor 2, [Score=107, Expect=4e-25]} {Celegans: WBGene00013974, npr-9, Galanin-like G-protein coupled receptor npr-9, [Score=100, Expect=6e-23]} {Smed: dd_Smed_v6_15151_0_1, dd_Smed_v6_15151_0_1, [RH, Score=244, Expect=7e-77]}

Mlig455_008607 {REF} {Length: 1678} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=148.1]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=26.6]; Serpentine type 7TM GPCR chemoreceptor Sru [PF10322.11, score=19.9]} {Human: ENSG00000182687, GALR2, galanin receptor 2, [Score=145, Expect=3e-39]} {Mouse: ENSMUSG00000020793, Galr2, galanin receptor 2, [Score=136, Expect=4e-36]} {Dmel: FBgn0036789, AstC-R2, Allatostatin C receptor 2, [Score=107, Expect=4e-25]} {Celegans: WBGene00013974, npr-9, Galanin-like G-protein coupled receptor npr-9, [Score=100, Expect=6e-23]} {Smed: dd_Smed_v6_15151_0_1, dd_Smed_v6_15151_0_1, [RH, Score=244, Expect=7e-77]}
96. MligTC455_13236 1 0.03 Mlig455_029625

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_029625 {REF} {Length: 899} {NoTransDecoderORF}
97. MligTC455_13917 50 1.05 Mlig455_006935, Mlig455_017950

Neo: -

Age: -

 0.982 - - - - 0.982 -

Mlig455_006935 {REF} {Length: 1553} {RNA1310_24840} {RNA815_41829}

Mlig455_017950 {REF} {Length: 1661} {RNA1310_24840} {RNA815_41829}
98. MligTC455_14009 6 0.12 Mlig455_059593

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_059593 {REF} {Length: 242} {NoTransDecoderORF} {RNA1509_47234} {RNA1310_54132} {RNA815_14343.2}
99. MligTC455_14393 3 0.06 Mlig455_008893

Neo: -

Age: Up-Down-Down

 0.982 - - - - 0.982 - Mlig455_008893 {REF} {Length: 4218} {TRANSSPLICED} {Mouse: ENSMUSG00000061186, Sfmbt2, Scm-like with four mbt domains 2, [Score=57.0, Expect=4e-08]} {Celegans: WBGene00018026, F35A5.4, [Score=51.6, Expect=9e-07]} {RNA1509_26220} {RNA1310_42977} {RNA815_20159}
100. MligTC455_14784 1 0.02 Mlig455_067566

Neo: -

Age: -

 0.982 - - - - 0.982 - Mlig455_067566 {REF} {Length: 174} {NoTransDecoderORF}

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