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Results for MligTC455_36805

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_36805 131 2.73 Mlig455_021546

Neo: -

Age: Down-Up-Down

 SMDT1 Mlig455_021546 {REF} {Length: 1593} {TRANSSPLICED} {Pfam: Putative mitochondrial precursor protein [PF10161.11, score=62.8]} {Human: ENSG00000183172, SMDT1, single-pass membrane protein with aspartate rich tail 1, [Score=45.4, Expect=5e-07]; ENSG00000272835, SMDT1, single-pass membrane protein with aspartate rich tail 1, [Score=45.4, Expect=5e-07]; ENSG00000272901, SMDT1, single-pass membrane protein with aspartate rich tail 1, [Score=45.4, Expect=5e-07]; ENSG00000274112, SMDT1, single-pass membrane protein with aspartate rich tail 1, [Score=45.4, Expect=5e-07]} {Mouse: ENSMUSG00000022452, Smdt1, single-pass membrane protein with aspartate rich tail 1, [Score=45.4, Expect=4e-07]} {Dmel: FBgn0062440, EMRE, Essential MCU regulator, [Score=50.1, Expect=3e-09]} {Celegans: WBGene00008980, emre-1, Essential MCU regulator, mitochondrial, [Score=50.1, Expect=3e-09]} {Smed: dd_Smed_v6_4158_0_1, dd_Smed_v6_4158_0_1, [Score=70.1, Expect=3e-17]} {RNA1509_31015} {RNA1310_41051.2} {RNA815_13700.1}

Cumulative graph for MligTC455_36805

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.527 2.201 0.40297 1.00000
RegionR2 -0.618 2.201 0.95364 1.00000
RegionR3 0.25 2.201 0.67122 1.00000
RegionR4 2.382 2.201 0.01330 0.07534
RegionR5 1.568 2.201 0.03307 0.13910
RegionR6 -0.525 2.201 0.94252 1.00000
RegionR7 0.785 2.201 0.42423 1.00000
RegionR8 -5.369 2.201 0.07074 0.50976

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -5.748 2.201 0.28081 0.98107
RegenerationR2 -0.149 2.201 0.80529 0.99114
RegenerationR3 -0.148 2.201 0.82946 0.99049
RegenerationR4 -0.453 2.201 0.52833 0.88358
RegenerationR5 -0.829 2.201 0.17605 0.60528
RegenerationR6 0.501 2.201 0.55408 0.84167
RegenerationBL 1.126 2.201 0.46458 0.83114
RegenerationTP 1.476 2.201 0.47526 0.88453


Genes with expression patterns similar to MligTC455_36805

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_36805 131 2.73 Mlig455_021546

Neo: -

Age: Down-Up-Down

 SMDT1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_021546 {REF} {Length: 1593} {TRANSSPLICED} {Pfam: Putative mitochondrial precursor protein [PF10161.11, score=62.8]} {Human: ENSG00000183172, SMDT1, single-pass membrane protein with aspartate rich tail 1, [Score=45.4, Expect=5e-07]; ENSG00000272835, SMDT1, single-pass membrane protein with aspartate rich tail 1, [Score=45.4, Expect=5e-07]; ENSG00000272901, SMDT1, single-pass membrane protein with aspartate rich tail 1, [Score=45.4, Expect=5e-07]; ENSG00000274112, SMDT1, single-pass membrane protein with aspartate rich tail 1, [Score=45.4, Expect=5e-07]} {Mouse: ENSMUSG00000022452, Smdt1, single-pass membrane protein with aspartate rich tail 1, [Score=45.4, Expect=4e-07]} {Dmel: FBgn0062440, EMRE, Essential MCU regulator, [Score=50.1, Expect=3e-09]} {Celegans: WBGene00008980, emre-1, Essential MCU regulator, mitochondrial, [Score=50.1, Expect=3e-09]} {Smed: dd_Smed_v6_4158_0_1, dd_Smed_v6_4158_0_1, [Score=70.1, Expect=3e-17]} {RNA1509_31015} {RNA1310_41051.2} {RNA815_13700.1}
2. MligTC455_27079 28 0.58 Mlig455_022102

Neo: -

Age: -

 1.801 - 0.967 - - 0.834 - Mlig455_022102 {REF} {Length: 1305} {RNA1509_44223} {RNA1310_77029} {RNA815_64986}
3. MligTC455_19084 292 6.08 Mlig455_021271

Neo: -

Age: -

 1.799 - - 0.848 - 0.951 - Mlig455_021271 {REF} {Length: 2744} {RNA1509_30062, RNA1509_39251} {RNA1310_9860, RNA1509_30062, RNA1509_39251} {RNA1509_30062, RNA1509_39251, RNA815_3403}
4. MligTC455_42557 354 7.38 Mlig455_026024

Neo: -

Age: -

 1.715 - - 0.746 - 0.969 - Mlig455_026024 {REF} {Length: 1890} {TRANSSPLICED} {RNA1509_23566, RNA1509_54428, RNA1509_56722} {RNA1310_23201.2, RNA1509_23566, RNA1509_54428, RNA1509_56722} {RNA1509_23566, RNA1509_54428, RNA1509_56722, RNA815_9453.1}
5. MligTC455_14477 676 14.08 Mlig455_030081

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.270

 1.671 - - 0.718 - 0.953 - Mlig455_030081 {REF} {Length: 1773} {RNA1509_4043} {RNA1310_3308.1, RNA1509_4043} {RNA1509_4043, RNA815_1039.1}
6. MligTC455_41863 2653 55.27 Mlig455_003492, Mlig455_015564

Neo: -

Age: logFC(26M/2M)=-0.199

 ERICH2 1.671 - - 0.719 - 0.952 -

Mlig455_003492 {REF} {Length: 1511} {TRANSSPLICED} {Pfam: Fis1 C-terminal tetratricopeptide repeat [PF14853.8, score=19.5]} {Human: ENSG00000204334, ERICH2, glutamate rich 2, [RH, Score=60.1, Expect=4e-11]} {Mouse: ENSMUSG00000075302, Erich2, glutamate rich 2, [RH, Score=55.5, Expect=8e-09]} {RNA1509_23697, RNA1509_5420} {RNA1310_19735, RNA1509_23697, RNA1509_5420} {RNA1509_23697, RNA1509_5420, RNA815_20782}

Mlig455_015564 {REF} {Length: 1509} {TRANSSPLICED} {Pfam: Fis1 C-terminal tetratricopeptide repeat [PF14853.8, score=19.5]} {Human: ENSG00000204334, ERICH2, glutamate rich 2, [RH, Score=62.0, Expect=1e-11]} {Mouse: ENSMUSG00000075302, Erich2, glutamate rich 2, [RH, Score=55.8, Expect=6e-09]} {RNA1509_5420} {RNA1310_19735} {RNA815_20782}
7. MligTC455_52708 2548 53.08 Mlig455_033971

Neo: -

Age: -

Region-specific R2: 1.697

Region-enriched R2: 1.605/0.00000

 CROCC 0.982 - - - - 0.982 - Mlig455_033971 {REF} {Length: 8201} {TRANSSPLICED} {Pfam: Ciliary rootlet component, centrosome cohesion [PF15035.8, score=206.8]; Septation ring formation regulator, EzrA [PF06160.14, score=19.8]} {Human: ENSG00000058453, CROCC, ciliary rootlet coiled-coil, rootletin, [Score=885, Expect=0.0]} {Mouse: ENSMUSG00000040860, Crocc, ciliary rootlet coiled-coil, rootletin, [Score=889, Expect=0.0]} {Dmel: FBgn0039152, Root, Rootletin, [Score=372, Expect=1e-103]} {Celegans: WBGene00022500, lfi-1, Lin-5 (Five) Interacting protein, [RH, Score=167, Expect=7e-41]} {Smed: dd_Smed_v6_1404_0_1, dd_Smed_v6_1404_0_1, [RH, Score=1909, Expect=0.0]} {RNA1509_137} {RNA1310_2877.1} {RNA815_204}
8. MligTC455_21803 1070 22.29 Mlig455_051085

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.341

 0.976 - - - - 0.976 - Mlig455_051085 {REF} {Length: 13899} {TRANSSPLICED} {Smed: dd_Smed_v6_4420_0_2, dd_Smed_v6_4420_0_2, [Score=53.1, Expect=3e-06]} {RNA1509_25269} {RNA1310_284.1} {RNA815_96}
9. MligTC455_12860 50 1.03 Mlig455_029552, Mlig455_040429, Mlig455_040461

Neo: -

Age: -

 MFAP4 0.968 - 0.968 - - - -

Mlig455_029552 {REF} {Length: 1565} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=154.7]} {Human: ENSG00000166482, MFAP4, microfibril associated protein 4, [RH, Score=139, Expect=3e-39]} {Mouse: ENSMUSG00000042436, Mfap4, microfibrillar-associated protein 4, [Score=139, Expect=2e-39]; ENSMUSG00000026841, Fibcd1, fibrinogen C domain containing 1, [Score=138, Expect=2e-37]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=137, Expect=6e-37]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=136, Expect=2e-36]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=135, Expect=5e-36]} {Dmel: FBgn0034160, CG5550, [Score=118, Expect=9e-32]} {Celegans: WBGene00017013, ensh-1, [Score=58.9, Expect=1e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=124, Expect=4e-32]} {RNA1509_26827} {RNA1310_72808} {RNA815_44140}

Mlig455_040429 {REF} {Length: 1034} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=55.4]} {Human: ENSG00000166482, MFAP4, microfibril associated protein 4, [Score=67.0, Expect=1e-12]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=65.9, Expect=7e-12]; ENSG00000160339, FCN2, ficolin 2, [Score=65.1, Expect=7e-12]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=65.1, Expect=2e-11]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=65.1, Expect=2e-11]} {Mouse: ENSMUSG00000033860, Fgg, fibrinogen gamma chain, [Score=67.0, Expect=3e-12]; ENSMUSG00000042436, Mfap4, microfibrillar-associated protein 4, [Score=66.2, Expect=2e-12]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=65.9, Expect=5e-12]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=64.7, Expect=1e-11]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=64.7, Expect=2e-11]} {Dmel: FBgn0003326, sca, scabrous, [Score=58.2, Expect=2e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=60.8, Expect=1e-10]} {RNA1509_26827} {RNA1310_31840} {RNA815_17173.3}

Mlig455_040461 {REF} {Length: 1629} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=154.7]} {Human: ENSG00000166482, MFAP4, microfibril associated protein 4, [RH, Score=139, Expect=3e-39]} {Mouse: ENSMUSG00000042436, Mfap4, microfibrillar-associated protein 4, [Score=139, Expect=2e-39]; ENSMUSG00000026841, Fibcd1, fibrinogen C domain containing 1, [Score=138, Expect=2e-37]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=137, Expect=6e-37]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=136, Expect=2e-36]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=135, Expect=5e-36]} {Dmel: FBgn0034160, CG5550, [Score=118, Expect=9e-32]} {Celegans: WBGene00017013, ensh-1, [Score=58.9, Expect=1e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=124, Expect=4e-32]} {RNA1509_26827} {RNA1310_72808} {RNA815_44140}
10. MligTC455_28794 33 0.68 Mlig455_043620, Mlig455_043652

Neo: Irradiation

Age: Up-Down-Down

 0.968 - - - - 0.968 -

Mlig455_043620 {REF} {Length: 1703} {Pfam: Tetraspanin family [PF00335.22, score=51.7]} {Smed: dd_Smed_v6_1719_0_2, dd_Smed_v6_1719_0_2, [Score=50.8, Expect=4e-07]} {RNA1509_14599} {RNA1310_20055.2} {RNA815_15207}

Mlig455_043652 {REF} {Length: 915} {TRANSSPLICED} {Pfam: Tetraspanin family [PF00335.22, score=49.3]} {Smed: dd_Smed_v6_1719_0_2, dd_Smed_v6_1719_0_2, [Score=48.5, Expect=6e-07]} {RNA1509_14599} {RNA1310_20055.2} {RNA815_15207}
11. MligTC455_39885 271 5.64 Mlig455_008315

Neo: -

Age: logFC(26M/2M)=-0.503

 0.968 - - - - 0.968 - Mlig455_008315 {REF} {Length: 2782} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=79.1]; GDP-mannose 4,6 dehydratase [PF16363.7, score=55.6]; RmlD substrate binding domain [PF04321.19, score=35.7]; Male sterility protein [PF07993.14, score=33.4]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=25.0]; Polysaccharide biosynthesis protein [PF02719.17, score=21.4]} {Mouse: ENSMUSG00000021953, Tdh, L-threonine dehydrogenase, [RH, Score=415, Expect=7e-144]} {Dmel: FBgn0036997, CG5955, [RH, Score=444, Expect=8e-156]} {Celegans: WBGene00017262, F08F3.4, [RH, Score=340, Expect=3e-115]} {Smed: dd_Smed_v6_12075_0_1, dd_Smed_v6_12075_0_1, [RH, Score=444, Expect=1e-156]} {RNA1509_13224, RNA1509_26090, RNA1509_38138, RNA1509_38407, RNA1509_44687} {RNA1310_15323, RNA1509_13224, RNA1509_26090, RNA1509_38138, RNA1509_38407, RNA1509_44687} {RNA1509_13224, RNA1509_26090, RNA1509_38138, RNA1509_38407, RNA1509_44687, RNA815_7207.1}
12. MligTC455_42587 40 0.83 Mlig455_061647

Neo: -

Age: -

 0.966 - 0.966 - - - - Mlig455_061647 {REF} {Length: 311} {NoTransDecoderORF} {RNA1509_24363} {RNA1310_12790.1} {RNA815_5920}
13. MligTC455_22397 123 2.55 Mlig455_007094, Mlig455_008909, Mlig455_015478, Mlig455_016547, Mlig455_037908, Mlig455_038997, Mlig455_051315

Neo: -

Age: -

 0.965 - - - - 0.965 -

Mlig455_007094 {REF} {Length: 1370} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_008909 {REF} {Length: 529} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_015478 {REF} {Length: 1396} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_016547 {REF} {Length: 518} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_037908 {REF} {Length: 4536} {RNA1509_32371} {RNA1310_7877} {RNA815_19983}

Mlig455_038997 {REF} {Length: 520} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_051315 {REF} {Length: 240} {NoTransDecoderORF} {RNA1509_51049} {RNA1310_28962.1} {RNA815_23816.2}
14. MligTC455_30093 165 3.43 Mlig455_006983

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.588

 0.962 - - - - 0.962 - Mlig455_006983 {REF} {Length: 1958} {Pfam: Rel homology DNA-binding domain [PF00554.24, score=60.6]; Uncharacterised protein family (UPF0172) [PF03665.15, score=18.8]} {RNA1509_55534} {RNA1310_1280.1} {RNA815_6392}
15. MligTC455_45179 4166 86.78 Mlig455_048432

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.401

 CFAP20 0.96 - - - - 0.960 - Mlig455_048432 {REF} {Length: 1648} {Pfam: Protein of unknown function (DUF667) [PF05018.15, score=310.7]} {Human: ENSG00000070761, CFAP20, cilia and flagella associated protein 20, [RH, Score=367, Expect=4e-131]} {Mouse: ENSMUSG00000031796, Cfap20, cilia and flagella associated protein 20, [RH, Score=370, Expect=2e-132]} {Dmel: FBgn0032248, Bug22, Basal body up regulated gene 22, [RH, Score=368, Expect=9e-132]} {Celegans: WBGene00008288, C54C6.6, Cilia- and flagella-associated protein 20, [RH, Score=345, Expect=1e-122]} {Smed: dd_Smed_v6_4843_0_1, dd_Smed_v6_4843_0_1, [RH, Score=362, Expect=2e-129]} {RNA1509_1898} {RNA1310_20376.1} {RNA815_8129.1}
16. MligTC455_20126 1086 22.63 Mlig455_049824

Neo: -

Age: -

 SLC2A1 0.959 - - - - 0.959 - Mlig455_049824 {REF} {Length: 3566} {Pfam: Sugar (and other) transporter [PF00083.26, score=307.8]; Major Facilitator Superfamily [PF07690.18, score=50.0]} {Human: ENSG00000117394, SLC2A1, solute carrier family 2 member 1, [Score=289, Expect=2e-92]; ENSG00000163581, SLC2A2, solute carrier family 2 member 2, [Score=275, Expect=1e-86]} {Mouse: ENSMUSG00000028645, Slc2a1, solute carrier family 2 (facilitated glucose transporter), member 1, [Score=287, Expect=6e-92]; ENSMUSG00000027690, Slc2a2, solute carrier family 2 (facilitated glucose transporter), member 2, [Score=278, Expect=5e-88]} {Dmel: FBgn0264574, Glut1, Glucose transporter 1, [Score=296, Expect=7e-95]} {Celegans: WBGene00019207, fgt-1, Facilitated glucose transporter protein 1, [Score=239, Expect=1e-73]} {Smed: dd_Smed_v6_4396_0_1, dd_Smed_v6_4396_0_1, [Score=247, Expect=6e-77]} {RNA1509_29953} {RNA1310_18869} {RNA815_4904.1}
17. MligTC455_28767 39 0.81 Mlig455_047012

Neo: -

Age: -

 UNC50 0.958 - - - - 0.958 - Mlig455_047012 {REF} {Length: 5005} {TRANSSPLICED} {Pfam: UNC-50 family [PF05216.15, score=201.1]} {Human: ENSG00000115446, UNC50, unc-50 inner nuclear membrane RNA binding protein, [Score=205, Expect=2e-66]} {Mouse: ENSMUSG00000026111, Unc50, unc-50 homolog, [Score=204, Expect=7e-67]} {Dmel: FBgn0037609, CG9773, [Score=181, Expect=5e-57]} {Celegans: WBGene00006785, unc-50, [Score=159, Expect=2e-48]} {Smed: dd_Smed_v6_7806_0_1, dd_Smed_v6_7806_0_1, [Score=198, Expect=6e-64]} {RNA1509_2515} {RNA1310_23566} {RNA815_3258.1}
18. MligTC455_28901 2683 55.89 Mlig455_000702, Mlig455_000756

Neo: -

Age: -

 CNTRL 0.957 - - - - 0.957 -

Mlig455_000702 {REF} {Length: 7735} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=62.9]; Leucine rich repeat [PF13855.8, score=47.3]; Crescentin protein [PF19220.2, score=23.5]} {Human: ENSG00000119397, CNTRL, centriolin, [Score=217, Expect=9e-56]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [Score=217, Expect=7e-56]} {Dmel: FBgn0032163, TbCMF46, [Score=85.5, Expect=3e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [Score=189, Expect=6e-48]} {RNA1509_7114} {RNA1310_12566} {RNA815_3884}

Mlig455_000756 {REF} {Length: 7584} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=65.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=61.9]; Leucine rich repeat [PF13855.8, score=45.8]} {Human: ENSG00000119397, CNTRL, centriolin, [RH, Score=254, Expect=4e-67]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [RH, Score=257, Expect=4e-68]} {Dmel: FBgn0032163, TbCMF46, [Score=84.7, Expect=4e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [RH, Score=199, Expect=9e-51]} {RNA1509_40686, RNA1509_7114} {RNA1310_1213, RNA1509_40686} {RNA1509_40686, RNA815_4518}
19. MligTC455_47329 793 16.52 Mlig455_025847, Mlig455_025942

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.434

 DSTYK 0.957 - - - - 0.957 -

Mlig455_025847 {REF} {Length: 4190} {Pfam: Protein kinase domain [PF00069.27, score=136.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.6]; Dynamin family [PF00350.25, score=73.6]; 50S ribosome-binding GTPase [PF01926.25, score=31.7]; Elongation factor Tu GTP binding domain [PF00009.29, score=26.7]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.7]} {Human: ENSG00000133059, DSTYK, dual serine/threonine and tyrosine protein kinase, [Score=179, Expect=1e-45]} {Mouse: ENSMUSG00000042046, Dstyk, dual serine/threonine and tyrosine protein kinase, [Score=193, Expect=2e-50]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=95.9, Expect=5e-20]} {Celegans: WBGene00013643, Y105C5A.24, [Score=100, Expect=9e-22]} {Smed: dd_Smed_v6_1371_0_1, dd_Smed_v6_1371_0_1, [RH, Score=401, Expect=6e-125]} {RNA1509_27256, RNA1509_31736} {RNA1310_3463.1, RNA1509_27256} {RNA1509_27256, RNA815_1104.1}

Mlig455_025942 {REF} {Length: 4065} {Pfam: Protein kinase domain [PF00069.27, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Dynamin family [PF00350.25, score=73.6]; 50S ribosome-binding GTPase [PF01926.25, score=31.7]; Elongation factor Tu GTP binding domain [PF00009.29, score=28.6]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.5]} {Human: ENSG00000133059, DSTYK, dual serine/threonine and tyrosine protein kinase, [Score=181, Expect=2e-46]} {Mouse: ENSMUSG00000042046, Dstyk, dual serine/threonine and tyrosine protein kinase, [Score=195, Expect=3e-51]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=97.8, Expect=1e-20]} {Celegans: WBGene00013643, Y105C5A.24, [Score=99.8, Expect=1e-21]} {Smed: dd_Smed_v6_1371_0_1, dd_Smed_v6_1371_0_1, [RH, Score=397, Expect=2e-123]} {RNA1509_31736} {RNA1310_3463.1} {RNA815_1104.1}
20. MligTC455_16002 752 15.67 Mlig455_062545

Neo: -

Age: -

 TTC16 0.956 - - - - 0.956 - Mlig455_062545 {REF} {Length: 2280} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=82.7]; Tetratricopeptide repeat [PF00515.30, score=64.9]; TPR repeat [PF13414.8, score=58.1]; Tetratricopeptide repeat [PF13432.8, score=57.0]; Tetratricopeptide repeat [PF13181.8, score=56.4]; Tetratricopeptide repeat [PF13428.8, score=54.2]; Tetratricopeptide repeat [PF14559.8, score=42.2]; Tetratricopeptide repeat [PF13424.8, score=41.4]; Tetratricopeptide repeat [PF13371.8, score=32.2]; Tetratricopeptide repeat [PF13176.8, score=31.2]; Tetratricopeptide repeat [PF13431.8, score=24.0]; NMDA receptor-regulated protein 1 [PF12569.10, score=23.7]; Tetratricopeptide repeat [PF13174.8, score=21.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.2]} {Human: ENSG00000167094, TTC16, tetratricopeptide repeat domain 16, [RH, Score=291, Expect=3e-86]} {Mouse: ENSMUSG00000039021, Ttc16, tetratricopeptide repeat domain 16, [RH, Score=295, Expect=9e-89]} {Celegans: WBGene00000500, chn-1, C-term of Hsp70-iNteracting protein (CHIP family); Hsp70-interacting protein, [Score=50.8, Expect=1e-06]} {Smed: dd_Smed_v6_11894_0_1, dd_Smed_v6_11894_0_1, [RH, Score=447, Expect=1e-147]} {RNA1509_9009} {RNA1310_10645.1, RNA1509_9009} {RNA1509_9009, RNA815_3627}
21. MligTC455_50833 43 0.9 Mlig455_040268

Neo: -

Age: -

 ANK2 0.956 - - - - 0.956 - Mlig455_040268 {REF} {Length: 4393} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=34.5]; Ankyrin repeats (many copies) [PF13637.8, score=29.5]; Ankyrin repeats (many copies) [PF13857.8, score=25.8]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=61.2, Expect=1e-08]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=63.5, Expect=9e-10]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=68.2, Expect=4e-11]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=55.5, Expect=3e-07]} {Smed: dd_Smed_v6_13669_0_1, dd_Smed_v6_13669_0_1, [Score=82.0, Expect=1e-15]} {RNA1509_33286} {RNA1310_11240, RNA1509_33286} {RNA1509_33286, RNA815_17700}
22. MligTC455_31427 429 8.94 Mlig455_024101

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.449

 CHRNA3 0.955 - - - - 0.955 - Mlig455_024101 {REF} {Length: 2557} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=242.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=210.4]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=395, Expect=3e-131]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=377, Expect=1e-122]} {Mouse: ENSMUSG00000027577, Chrna4, cholinergic receptor, nicotinic, alpha polypeptide 4, [Score=372, Expect=8e-121]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=363, Expect=2e-119]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=355, Expect=4e-116]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=443, Expect=2e-149]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=387, Expect=2e-128]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=382, Expect=2e-126]} {RNA1509_19028} {RNA1310_8041, RNA1509_19028} {RNA1509_19028, RNA815_11178}
23. MligTC455_32487 595 12.39 Mlig455_017119

Neo: -

Age: logFC(26M/2M)=-0.391

 0.955 - - - - 0.955 - Mlig455_017119 {REF} {Length: 2322} {RNA1509_10657} {RNA1310_11689, RNA1509_10657} {RNA1509_10657, RNA815_5499}
24. MligTC455_33706 819 17.07 Mlig455_008312

Neo: -

Age: -

 XRRA1 0.955 - - - - 0.955 - Mlig455_008312 {REF} {Length: 3552} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=41.9]; Leucine rich repeat [PF13855.8, score=29.4]} {Human: ENSG00000166435, XRRA1, X-ray radiation resistance associated 1, [RH, Score=163, Expect=3e-44]} {Mouse: ENSMUSG00000035211, Xrra1, X-ray radiation resistance associated 1, [RH, Score=171, Expect=1e-43]} {Smed: dd_Smed_v6_13519_0_1, dd_Smed_v6_13519_0_1, [RH, Score=154, Expect=5e-38]} {RNA1509_21148, RNA1509_45583} {RNA1310_16743.1, RNA1509_21148, RNA1509_45583} {RNA1509_21148, RNA1509_45583, RNA815_17679}
25. MligTC455_41699 427 8.9 Mlig455_004636

Neo: -

Age: -

 CYP2U1 0.955 - - - - 0.955 - Mlig455_004636 {REF} {Length: 2637} {Pfam: Cytochrome P450 [PF00067.24, score=213.9]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=177, Expect=4e-53]} {Mouse: ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=171, Expect=3e-49]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=171, Expect=3e-49]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=167, Expect=1e-47]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=119, Expect=4e-30]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [Score=151, Expect=5e-42]} {Smed: dd_Smed_v6_2351_0_2, dd_Smed_v6_2351_0_2, [Score=187, Expect=1e-55]} {RNA1509_44189} {RNA1310_1872.1} {RNA815_585.1}
26. MligTC455_48224 130 2.7 Mlig455_033977

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.589

 GLRA3 0.955 - - - - 0.955 - Mlig455_033977 {REF} {Length: 2696} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=151.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=128.7]} {Human: ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=266, Expect=7e-83]; ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=266, Expect=4e-83]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=265, Expect=1e-82]; ENSG00000188828, GLRA4, glycine receptor alpha 4, [Score=259, Expect=8e-81]; ENSG00000166206, GABRB3, gamma-aminobutyric acid type A receptor beta3 subunit, [Score=253, Expect=4e-78]} {Mouse: ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=271, Expect=9e-85]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=266, Expect=3e-83]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=264, Expect=2e-82]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=260, Expect=6e-81]} {Dmel: FBgn0024963, GluClalpha, [Score=252, Expect=6e-78]} {Celegans: WBGene00001594, glc-4, Glutamate-gated ChLoride channel, [RH, Score=244, Expect=2e-74]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=221, Expect=4e-66]} {RNA1310_13574.1} {RNA815_10577.1}
27. MligTC455_16992 25 0.51 Mlig455_058183

Neo: -

Age: -

 0.954 - - - - 0.954 - Mlig455_058183 {REF} {Length: 3198} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=123.5]; WSC domain [PF01822.21, score=40.6]} {Celegans: WBGene00003168, mec-4, Degenerin mec-4, [Score=59.7, Expect=7e-09]} {Smed: dd_Smed_v6_21491_0_1, dd_Smed_v6_21491_0_1, [Score=58.9, Expect=8e-09]} {RNA1509_20328} {RNA1310_3478} {RNA815_19382.1}
28. MligTC455_30865 559 11.65 Mlig455_050410

Neo: -

Age: logFC(26M/2M)=-0.223

 0.954 - - - - 0.954 - Mlig455_050410 {REF} {Length: 2602} {TRANSSPLICED} {RNA1509_18063} {RNA1310_7936.1, RNA1509_18063} {RNA1509_18063, RNA815_2370.1}
29. MligTC455_47868 5452 113.57 Mlig455_031216

Neo: -

Age: logFC(26M/2M)=-0.277

 TEKT1 0.954 - - - - 0.954 - Mlig455_031216 {REF} {Length: 1751} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=439.2]} {Human: ENSG00000167858, TEKT1, tektin 1, [RH, Score=379, Expect=4e-129]} {Mouse: ENSMUSG00000020799, Tekt1, tektin 1, [RH, Score=373, Expect=9e-127]} {Dmel: FBgn0052820, CG32820, [Score=217, Expect=4e-65]} {Smed: dd_Smed_v6_3287_0_2, dd_Smed_v6_3287_0_2, [RH, Score=448, Expect=1e-156]} {RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215} {RNA1310_15062.1, RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215} {RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215, RNA815_6688}
30. MligTC455_51903 1283 26.73 Mlig455_021657, Mlig455_067458

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.872

 CHRNB1, CHRNB3 0.954 - - - - 0.954 -

Mlig455_021657 {REF} {Length: 2044} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=147.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=73.5]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=193, Expect=5e-56]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=1e-54]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=187, Expect=8e-54]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=186, Expect=1e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=179, Expect=5e-51]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=176, Expect=3e-49]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=174, Expect=9e-49]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=346, Expect=9e-116]} {RNA1509_8724} {RNA1310_17144.1, RNA1509_8724} {RNA1509_8724, RNA815_6285}

Mlig455_067458 {REF} {Length: 1512} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=43.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=18.7]} {Human: ENSG00000283946, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000170175, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=47.8, Expect=1e-05]} {Mouse: ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=47.4, Expect=1e-05]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=46.6, Expect=1e-05]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=96.7, Expect=1e-22]} {RNA1509_8724} {RNA1310_17144.1} {RNA815_6285}
31. MligTC455_22729 1065 22.18 Mlig455_006821, Mlig455_054658

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.317

Region-enriched R2: 1.624/0.00561

 DNAH8 0.953 - - - - 0.953 -

Mlig455_006821 {REF} {Length: 14560} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=537.8]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=466.2]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=416.8]; Dynein heavy chain C-terminal domain [PF18199.3, score=324.6]; ATP-binding dynein motor region [PF12781.9, score=291.0]; P-loop containing dynein motor region D4 [PF12780.9, score=290.7]; P-loop containing dynein motor region [PF12775.9, score=226.6]; Dynein heavy chain AAA lid domain [PF18198.3, score=177.7]; Microtubule-binding stalk of dynein motor [PF12777.9, score=141.5]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=134.5]; AAA domain (dynein-related subfamily) [PF07728.16, score=81.4]; Dynein heavy chain AAA lid domain [PF17852.3, score=76.3]; AAA+ lid domain [PF17857.3, score=62.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=25.1]} {Human: ENSG00000124721, DNAH8, dynein axonemal heavy chain 8, [RH, Score=5670, Expect=0.0]} {Mouse: ENSMUSG00000033826, Dnah8, dynein, axonemal, heavy chain 8, [RH, Score=5682, Expect=0.0]} {Dmel: FBgn0267432, kl-3, male fertility factor kl3, [RH, Score=4460, Expect=0.0]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=980, Expect=0.0]} {Smed: dd_Smed_v6_4176_0_1, dd_Smed_v6_4176_0_1, [RH, Score=6801, Expect=0.0]} {RNA1509_11311, RNA1509_12955, RNA1509_201, RNA1509_25369, RNA1509_50556, RNA1509_55453} {RNA1310_42, RNA1509_11311, RNA1509_12955, RNA1509_201, RNA1509_25369, RNA1509_50556, RNA1509_55453} {RNA1509_11311, RNA1509_12955, RNA1509_201, RNA1509_25369, RNA1509_50556, RNA1509_55453, RNA815_121}

Mlig455_054658 {REF} {Length: 1087} {Pfam: Phage integrase, N-terminal SAM-like domain [PF13495.8, score=25.6]; Phage integrase, N-terminal SAM-like domain [PF02899.19, score=24.9]} {Human: ENSG00000124721, DNAH8, dynein axonemal heavy chain 8, [RH, Score=59.3, Expect=7e-10]} {Mouse: ENSMUSG00000033826, Dnah8, dynein, axonemal, heavy chain 8, [Score=57.4, Expect=1e-08]} {Smed: dd_Smed_v6_4176_0_1, dd_Smed_v6_4176_0_1, [Score=84.0, Expect=1e-17]} {RNA1509_25369} {RNA1310_25264} {RNA815_121}
32. MligTC455_22730 314 6.54 Mlig455_055170

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.352

 DNAH8 0.953 - - - - 0.953 - Mlig455_055170 {REF} {Length: 14554} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=537.5]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=466.2]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=416.8]; Dynein heavy chain C-terminal domain [PF18199.3, score=324.9]; ATP-binding dynein motor region [PF12781.9, score=291.0]; P-loop containing dynein motor region D4 [PF12780.9, score=290.7]; P-loop containing dynein motor region [PF12775.9, score=226.5]; Dynein heavy chain AAA lid domain [PF18198.3, score=177.7]; Microtubule-binding stalk of dynein motor [PF12777.9, score=140.6]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=134.5]; AAA domain (dynein-related subfamily) [PF07728.16, score=81.4]; Dynein heavy chain AAA lid domain [PF17852.3, score=76.4]; AAA+ lid domain [PF17857.3, score=62.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=25.1]} {Human: ENSG00000124721, DNAH8, dynein axonemal heavy chain 8, [RH, Score=5668, Expect=0.0]} {Mouse: ENSMUSG00000033826, Dnah8, dynein, axonemal, heavy chain 8, [RH, Score=5678, Expect=0.0]} {Dmel: FBgn0267432, kl-3, male fertility factor kl3, [RH, Score=4459, Expect=0.0]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=980, Expect=0.0]} {Smed: dd_Smed_v6_4176_0_1, dd_Smed_v6_4176_0_1, [RH, Score=6801, Expect=0.0]} {RNA1509_201} {RNA1310_42} {RNA815_121}
33. MligTC455_29786 811 16.9 Mlig455_015969, Mlig455_015988

Neo: -

Age: Down-Up-Down

 0.953 - - - - 0.953 -

Mlig455_015969 {REF} {Length: 2588} {Pfam: Fez1 [PF06818.17, score=25.5]; Domain of unknown function (DUF4201) [PF13870.8, score=22.3]} {RNA1509_19113} {RNA1310_31445} {RNA815_4889.1}

Mlig455_015988 {REF} {Length: 2314} {Pfam: LMP repeated region [PF04778.14, score=20.0]} {RNA1509_19113} {RNA1310_28200} {RNA815_4889.1}
34. MligTC455_31804 143 2.99 Mlig455_059782

Neo: -

Age: logFC(26M/2M)=-0.656

 EFCAB6 0.953 - - - - 0.953 - Mlig455_059782 {REF} {Length: 4682} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=81.1]; EF-hand domain [PF08976.13, score=68.9]; EF-hand domain pair [PF13833.8, score=64.1]; EF-hand domain [PF13405.8, score=57.5]; EF hand [PF00036.34, score=53.3]; EF-hand domain [PF14658.8, score=35.8]; Family of unknown function (DUF5580) [PF17743.3, score=27.6]; EF hand [PF13202.8, score=22.4]} {Human: ENSG00000186976, EFCAB6, EF-hand calcium binding domain 6, [Score=91.3, Expect=7e-18]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=75.9, Expect=2e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=49.7, Expect=1e-06]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=50.8, Expect=4e-07]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=157, Expect=1e-40]} {RNA1509_11692} {RNA1310_3239.1} {RNA815_3758}
35. MligTC455_41286 4033 84.01 Mlig455_001654

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.221

 0.953 - - - - 0.953 - Mlig455_001654 {REF} {Length: 1603} {Smed: dd_Smed_v6_4625_0_1, dd_Smed_v6_4625_0_1, [RH, Score=148, Expect=4e-44]} {RNA1509_17667, RNA1509_22820, RNA1509_31710, RNA1509_41362, RNA1509_5500} {RNA1310_18662, RNA1509_17667, RNA1509_22820, RNA1509_31710, RNA1509_41362} {RNA1509_17667, RNA1509_22820, RNA1509_31710, RNA1509_41362, RNA815_10004.1}
36. MligTC455_44623 3349 69.77 Mlig455_040692, Mlig455_064561

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.362

 0.953 - - - - 0.953 -

Mlig455_040692 {REF} {Length: 1243} {Pfam: Domain of unknown function (DUF4476) [PF14771.8, score=37.3]} {Smed: dd_Smed_v6_50605_0_1, dd_Smed_v6_50605_0_1, [RH, Score=197, Expect=4e-63]} {RNA1509_7167} {RNA1310_27037, RNA1509_7167} {RNA1509_7167, RNA815_11150}

Mlig455_064561 {REF} {Length: 1230} {Pfam: Domain of unknown function (DUF4476) [PF14771.8, score=37.3]} {Smed: dd_Smed_v6_50605_0_1, dd_Smed_v6_50605_0_1, [RH, Score=197, Expect=4e-63]} {RNA1509_59684, RNA1509_7167} {RNA1310_27037, RNA1509_59684} {RNA1509_59684, RNA815_11150}
37. MligTC455_46254 1114 23.21 Mlig455_000448

Neo: -

Age: -

 CASC1 0.953 - - - - 0.953 - Mlig455_000448 {REF} {Length: 3104} {Pfam: Cancer susceptibility candidate 1 N-terminus [PF15927.7, score=168.4]; Cancer susceptibility candidate 1 C-terminal [PF12366.10, score=29.2]} {Human: ENSG00000118307, CASC1, cancer susceptibility 1, [RH, Score=320, Expect=4e-98]} {Mouse: ENSMUSG00000043541, Casc1, cancer susceptibility candidate 1, [RH, Score=295, Expect=2e-88]} {Dmel: FBgn0030889, CG15373, [RH, Score=83.6, Expect=4e-16]} {Smed: dd_Smed_v6_11291_0_1, dd_Smed_v6_11291_0_1, [RH, Score=521, Expect=7e-175]} {RNA1509_1842} {RNA1310_6962.1, RNA1509_1842} {RNA1509_1842, RNA815_2139}
38. MligTC455_51133 88 1.84 Mlig455_069320

Neo: Irradiation

Age: logFC(26M/2M)=0.963

 0.953 - 0.953 - - - - Mlig455_069320 {REF} {Length: 1727} {RNA1509_1239, RNA1509_3377, RNA1509_42} {RNA1310_10769, RNA1509_1239, RNA1509_3377} {RNA1509_1239, RNA1509_3377, RNA815_3639}
39. MligTC455_10524 19 0.39 Mlig455_039267

Neo: -

Age: -

 0.951 - - - - 0.951 - Mlig455_039267 {REF} {Length: 779} {NoTransDecoderORF} {RNA1310_22208} {RNA815_54327}
40. MligTC455_29773 152 3.18 Mlig455_061443

Neo: -

Age: -

 MAP3K19 0.951 - - - - 0.951 - Mlig455_061443 {REF} {Length: 2940} {Pfam: Protein kinase domain [PF00069.27, score=185.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.9]; Ankyrin repeats (many copies) [PF13637.8, score=51.0]; Ankyrin repeats (3 copies) [PF12796.9, score=33.9]; Fungal protein kinase [PF17667.3, score=26.2]; Ankyrin repeats (many copies) [PF13857.8, score=25.6]; ABC1 atypical kinase-like domain [PF03109.18, score=22.1]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=160, Expect=1e-41]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=163, Expect=2e-42]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=139, Expect=5e-35]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=133, Expect=5e-33]} {Smed: dd_Smed_v6_2030_0_16, dd_Smed_v6_2030_0_16, [Score=137, Expect=2e-35]} {RNA1509_48626} {RNA1310_31580} {RNA815_5323.1}
41. MligTC455_40947 334 6.97 Mlig455_035957

Neo: -

Age: Up-Down-Down

 FSIP1 0.951 - - - - 0.951 - Mlig455_035957 {REF} {Length: 3167} {TRANSSPLICED} {Pfam: FSIP1 family [PF15554.8, score=178.4]} {Human: ENSG00000150667, FSIP1, fibrous sheath interacting protein 1, [RH, Score=108, Expect=5e-24]} {Mouse: ENSMUSG00000027344, Fsip1, fibrous sheath-interacting protein 1, [RH, Score=101, Expect=4e-22]} {Smed: dd_Smed_v6_16017_0_1, dd_Smed_v6_16017_0_1, [RH, Score=119, Expect=2e-28]} {RNA1509_20339} {RNA1310_6204.1} {RNA815_13781}
42. MligTC455_51307 298 6.2 Mlig455_032037

Neo: -

Age: -

 DCTN1 0.951 - - - - 0.951 - Mlig455_032037 {REF} {Length: 3293} {TRANSSPLICED} {Pfam: CAP-Gly domain [PF01302.27, score=63.8]; Macoilin family [PF09726.11, score=17.4]} {Human: ENSG00000204843, DCTN1, dynactin subunit 1, [Score=56.2, Expect=2e-07]; ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=56.2, Expect=2e-07]; ENSG00000197892, KIF13B, kinesin family member 13B, [Score=55.8, Expect=2e-07]} {Mouse: ENSMUSG00000031865, Dctn1, dynactin 1, [Score=57.0, Expect=9e-09]} {Dmel: FBgn0033055, Tbce, Tubulin-specific chaperone E, [Score=64.3, Expect=3e-10]} {Smed: dd_Smed_v6_12415_0_2, dd_Smed_v6_12415_0_2, [Score=97.1, Expect=9e-21]} {RNA1509_15825} {RNA1310_31448.1} {RNA815_3703.1}
43. MligTC455_07075 23 0.48 Mlig455_017838

Neo: Int S/G2/M

Age: -

 0.95 - 0.950 - - - - Mlig455_017838 {REF} {Length: 589} {NoTransDecoderORF} {RNA1509_13746} {RNA1310_17949} {RNA815_52124}
44. MligTC455_29653 200 4.17 Mlig455_009145

Neo: -

Age: logFC(26M/2M)=0.607

 SETMAR 0.95 - 0.950 - - - - Mlig455_009145 {REF} {Length: 2358} {TRANSSPLICED} {Pfam: DDE superfamily endonuclease [PF13358.8, score=32.4]; Winged helix-turn helix [PF13551.8, score=31.6]; Homeodomain-like domain [PF13384.8, score=29.0]; Bacterial regulatory proteins, lacI family [PF00356.23, score=28.5]; Helix-turn-helix domain of resolvase [PF02796.17, score=24.3]; Helix-turn-helix domain [PF13518.8, score=23.4]; Bacterial regulatory proteins, tetR family [PF00440.25, score=23.1]; Helix-turn-helix [PF01381.24, score=21.9]; Winged helix-turn-helix DNA-binding [PF13412.8, score=21.4]; MarR family [PF12802.9, score=21.3]; Sugar-specific transcriptional regulator TrmB [PF01978.21, score=21.0]; HTH DNA binding domain [PF04967.14, score=21.0]; AsnC-type helix-turn-helix domain [PF13404.8, score=20.3]; Transposase [PF01498.20, score=19.3]} {Human: ENSG00000170364, SETMAR, SET domain and mariner transposase fusion gene, [Score=62.4, Expect=3e-10]} {Smed: dd_Smed_v6_16239_0_2, dd_Smed_v6_16239_0_2, [Score=69.3, Expect=4e-14]} {RNA1509_272} {RNA1310_26410} {RNA815_12134}
45. MligTC455_30192 1664 34.66 Mlig455_026693

Neo: -

Age: -

 FOXRED2 0.95 - - - - 0.950 - Mlig455_026693 {REF} {Length: 18036} {Pfam: Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=147.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=45.8]; HI0933-like protein [PF03486.16, score=31.1]; FAD dependent oxidoreductase [PF01266.26, score=26.0]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=25.0]; FAD binding domain [PF01494.21, score=22.8]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=22.5]; Flavin containing amine oxidoreductase [PF01593.26, score=21.9]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=20.1]} {Human: ENSG00000100350, FOXRED2, FAD dependent oxidoreductase domain containing 2, [RH, Score=493, Expect=4e-167]} {Mouse: ENSMUSG00000016552, Foxred2, FAD-dependent oxidoreductase domain containing 2, [RH, Score=498, Expect=3e-169]} {Celegans: WBGene00001479, fmo-4, Flavin-containing monooxygenase, [Score=53.5, Expect=4e-07]} {Smed: dd_Smed_v6_12138_0_1, dd_Smed_v6_12138_0_1, [RH, Score=474, Expect=4e-161]} {RNA1509_13675, RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978} {RNA1310_861.1, RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978} {RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978, RNA815_570.1}
46. MligTC455_31123 16 0.33 Mlig455_047127

Neo: -

Age: logFC(26M/2M)=-1.249

 TRPM7 0.95 - - - - 0.950 - Mlig455_047127 {REF} {Length: 4103} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=71.0]; Ankyrin repeats (many copies) [PF13637.8, score=51.0]; Ankyrin repeat [PF13606.8, score=36.0]; Ankyrin repeat [PF00023.32, score=31.6]; Ankyrin repeats (many copies) [PF13857.8, score=26.2]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=68.6, Expect=7e-11]; ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=67.8, Expect=1e-10]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=70.1, Expect=2e-11]; ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=68.9, Expect=4e-11]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=52.0, Expect=4e-06]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=55.5, Expect=2e-07]} {Smed: dd_Smed_v6_9288_0_1, dd_Smed_v6_9288_0_1, [Score=71.2, Expect=3e-12]} {RNA1509_12296} {RNA1310_1739} {RNA815_8702.1}
47. MligTC455_32519 147 3.06 Mlig455_017549

Neo: -

Age: logFC(26M/2M)=-0.495

 NWD2 0.95 - - - - 0.950 - Mlig455_017549 {REF} {Length: 6334} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=40.6]; AAA ATPase domain [PF13191.8, score=38.4]; NACHT domain [PF05729.14, score=34.5]; AAA domain [PF13481.8, score=20.7]; ATPase domain predominantly from Archaea [PF01637.20, score=20.2]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=347, Expect=8e-99]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=340, Expect=1e-96]} {Dmel: FBgn0038397, CG10185, [Score=472, Expect=9e-143]} {Celegans: WBGene00020254, T05C3.2, [Score=527, Expect=1e-162]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=380, Expect=2e-110]} {RNA1509_23488} {RNA1310_497.1} {RNA815_237}
48. MligTC455_44849 3056 63.66 Mlig455_014245

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.313

 LEXM 0.95 - - - - 0.950 - Mlig455_014245 {REF} {Length: 2724} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1} {RNA815_5377}
49. MligTC455_51902 1049 21.85 Mlig455_021705

Neo: -

Age: logFC(26M/2M)=-0.488

 CHRNB3 0.95 - - - - 0.950 - Mlig455_021705 {REF} {Length: 1861} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=147.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=72.7]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=191, Expect=2e-55]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=2e-54]; ENSG00000169684, CHRNA5, cholinergic receptor nicotinic alpha 5 subunit, [Score=182, Expect=6e-52]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=186, Expect=2e-53]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=185, Expect=2e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=182, Expect=4e-52]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=177, Expect=2e-49]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=174, Expect=7e-49]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=347, Expect=6e-116]} {RNA1509_8724} {RNA1310_17144.1} {RNA815_6285}

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