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Results for MligTC455_37591

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_37591 311 6.48 Mlig455_066725, Mlig455_066739

Neo: -

Age: -

Mlig455_066725 {REF} {Length: 3618} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=108.2]} {Smed: dd_Smed_v6_13734_0_20, dd_Smed_v6_13734_0_20, [Score=68.2, Expect=5e-12]} {RNA1509_56135} {RNA1310_34683.1} {RNA815_10209}

Mlig455_066739 {REF} {Length: 3559} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=108.2]} {Smed: dd_Smed_v6_13734_0_20, dd_Smed_v6_13734_0_20, [Score=68.2, Expect=5e-12]} {RNA1509_56135} {RNA1310_34683.1} {RNA815_10209}

Cumulative graph for MligTC455_37591

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.382 2.953 0.44459 1.00000
RegionR2 -0.58 2.953 0.45856 0.84569
RegionR3 -0.142 2.953 0.82429 1.00000
RegionR4 0.667 2.953 0.38504 0.70992
RegionR5 -1.23 2.953 0.05673 0.20497
RegionR6 -0.359 2.953 0.57882 1.00000
RegionR7 0.442 2.953 0.56869 1.00000
RegionR8 -0.18 2.953 0.87327 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.746 2.953 0.30681 1.00000
RegenerationR2 1.543 2.953 0.01564 0.20553
RegenerationR3 -0.414 2.953 0.57891 0.89864
RegenerationR4 0.246 2.953 0.73999 0.96747
RegenerationR5 0.432 2.953 0.55766 0.88982
RegenerationR6 0.768 2.953 0.30733 0.65585
RegenerationBL 0.66 2.953 0.44669 0.81391
RegenerationTP 0.201 2.953 0.82755 1.00000


Genes with expression patterns similar to MligTC455_37591

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_37591 311 6.48 Mlig455_066725, Mlig455_066739

Neo: -

Age: -

 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_066725 {REF} {Length: 3618} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=108.2]} {Smed: dd_Smed_v6_13734_0_20, dd_Smed_v6_13734_0_20, [Score=68.2, Expect=5e-12]} {RNA1509_56135} {RNA1310_34683.1} {RNA815_10209}

Mlig455_066739 {REF} {Length: 3559} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=108.2]} {Smed: dd_Smed_v6_13734_0_20, dd_Smed_v6_13734_0_20, [Score=68.2, Expect=5e-12]} {RNA1509_56135} {RNA1310_34683.1} {RNA815_10209}
2. MligTC455_16066 304 6.33 Mlig455_064090

Neo: -

Age: -

 PTPN21 1.866 - - - - 0.887 0.979 Mlig455_064090 {REF} {Length: 5193} {TRANSSPLICED} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=144.3]; FERM central domain [PF00373.20, score=54.7]; FERM N-terminal domain [PF09379.12, score=54.2]; FERM C-terminal PH-like domain [PF09380.12, score=31.2]} {Human: ENSG00000070778, PTPN21, protein tyrosine phosphatase, non-receptor type 21, [RH, Score=183, Expect=2e-46]} {Mouse: ENSMUSG00000021009, Ptpn21, protein tyrosine phosphatase, non-receptor type 21, [RH, Score=184, Expect=7e-47]} {Dmel: FBgn0031799, Pez, [RH, Score=134, Expect=2e-31]} {Celegans: WBGene00021507, Y41D4A.5, Protein-tyrosine-phosphatase, [Score=117, Expect=3e-27]} {Smed: dd_Smed_v6_9236_0_1, dd_Smed_v6_9236_0_1, [Score=120, Expect=2e-27]} {RNA1509_19016, RNA1509_40741, RNA1509_43576, RNA1509_52719} {RNA1310_988.1, RNA1509_19016, RNA1509_40741, RNA1509_43576, RNA1509_52719} {RNA1509_19016, RNA1509_40741, RNA1509_43576, RNA1509_52719, RNA815_4090}
3. MligTC455_19194 403 8.39 Mlig455_007445

Neo: -

Age: Up-Down-Down

 BFAR 1.865 - - - - 0.964 0.901 Mlig455_007445 {REF} {Length: 4108} {Pfam: Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=31.1]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=30.1]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=30.0]; zinc finger of C3HC4-type, RING [PF15227.8, score=29.7]; RING-type zinc-finger [PF13445.8, score=29.4]; Ring finger domain [PF13639.8, score=27.0]; zinc-RING finger domain [PF14634.8, score=25.5]; Prokaryotic RING finger family 4 [PF14447.8, score=22.2]; RING-H2 zinc finger domain [PF12678.9, score=19.9]} {Human: ENSG00000275618, BFAR, bifunctional apoptosis regulator, [RH, Score=48.9, Expect=7e-07]; ENSG00000103429, BFAR, bifunctional apoptosis regulator, [RH, Score=48.9, Expect=7e-07]} {Mouse: ENSMUSG00000022684, Bfar, bifunctional apoptosis regulator, [RH, Score=52.8, Expect=2e-08]; ENSMUSG00000057596, Trim30d, tripartite motif-containing 30D, [RH, Score=50.8, Expect=2e-07]} {Smed: dd_Smed_v6_10019_0_1, dd_Smed_v6_10019_0_1, [Score=46.2, Expect=2e-06]} {RNA1509_14967, RNA1509_23909, RNA1509_40881, RNA1509_45941, RNA1509_53684} {RNA1310_39360, RNA1509_14967, RNA1509_23909, RNA1509_40881, RNA1509_45941, RNA1509_53684} {RNA1509_14967, RNA1509_23909, RNA1509_40881, RNA1509_45941, RNA1509_53684, RNA815_20181}
4. MligTC455_29062 349 7.27 Mlig455_025890, Mlig455_062699

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=1.172

 1.789 - - - 0.814 0.975 -

Mlig455_025890 {REF} {Length: 482} {RNA1509_40044} {RNA1310_27474} {RNA815_24684}

Mlig455_062699 {REF} {Length: 4640} {RNA1509_40044} {RNA1310_6084} {RNA815_5170.1}
5. MligTC455_41001 142 2.95 Mlig455_041980

Neo: -

Age: Down-Up-Down

 1.721 - - - 0.770 0.951 - Mlig455_041980 {REF} {Length: 1792} {TRANSSPLICED} {Pfam: Glutathione S-transferase, N-terminal domain [PF13409.8, score=65.3]; Glutathione S-transferase, C-terminal domain [PF13410.8, score=33.8]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=26.9]} {RNA1509_28023} {RNA1310_17102.2} {RNA815_6006.1}
6. MligTC455_26512 128 2.67 Mlig455_069089

Neo: -

Age: Up-Down-Down

 PRKDC 1.71 - - - 0.743 0.967 - Mlig455_069089 {REF} {Length: 15905} {Pfam: NUC194 domain [PF08163.14, score=230.9]; DNA-PKcs, CC5 [PF19704.1, score=218.9]; Phosphatidylinositol 3- and 4-kinase [PF00454.29, score=139.7]; FAT domain [PF02259.25, score=33.6]; FATC domain [PF02260.22, score=27.0]; DDE superfamily endonuclease [PF13358.8, score=24.7]; Helix-turn-helix domain [PF13518.8, score=22.8]} {Human: ENSG00000253729, PRKDC, protein kinase, DNA-activated, catalytic subunit, [Score=652, Expect=0.0]} {Mouse: ENSMUSG00000022672, Prkdc, protein kinase, DNA activated, catalytic polypeptide, [Score=624, Expect=1e-178]} {Dmel: FBgn0021796, Tor, Target of rapamycin, [Score=152, Expect=8e-36]} {Celegans: WBGene00002583, let-363, Target of rapamycin homolog, [Score=149, Expect=3e-35]} {Smed: dd_Smed_v6_8462_0_2, dd_Smed_v6_8462_0_2, [RH, Score=284, Expect=5e-76]} {RNA1509_11402, RNA1509_47977, RNA1509_60024} {RNA1310_372, RNA1509_47977, RNA1509_60024} {RNA1509_47977, RNA1509_60024, RNA815_3968}
7. MligTC455_43342 1092 22.75 Mlig455_058411

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.547

Region-enriched R8: 3.182/0.00000
Region-enriched R7: 2.059/0.00370

Regeneration-downregulated TP: -1.723

Regeneration-depleted TP: -1.723

 1.691 - - - 0.738 - 0.953 Mlig455_058411 {REF} {Length: 4577} {RNA1509_25352, RNA1509_46976} {RNA1310_12893, RNA1509_25352} {RNA1509_25352, RNA815_3259.1}
8. MligTC455_27885 590 12.3 Mlig455_003748

Neo: -

Age: logFC(26M/2M)=1.037

 DSP 1.69 - - - - 0.971 0.719 Mlig455_003748 {REF} {Length: 27472} {Pfam: SH3 domain [PF17902.3, score=34.6]; Orthopoxvirus F14 protein [PF06076.14, score=19.1]} {Human: ENSG00000096696, DSP, desmoplakin, [Score=71.2, Expect=8e-11]} {Mouse: ENSMUSG00000054889, Dsp, desmoplakin, [Score=69.7, Expect=2e-10]} {Dmel: FBgn0013733, shot, short stop, [Score=79.7, Expect=1e-13]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=59.7, Expect=9e-08]} {Smed: dd_Smed_v6_8220_0_6, dd_Smed_v6_8220_0_6, [Score=162, Expect=4e-39]} {RNA1509_35456, RNA1509_39493, RNA1509_525, RNA1509_7595} {RNA1310_192.1, RNA1509_35456, RNA1509_39493, RNA1509_525, RNA1509_7595} {RNA1509_35456, RNA1509_39493, RNA1509_525, RNA1509_7595, RNA815_18.1}
9. MligTC455_47852 353 7.36 Mlig455_035401, Mlig455_061039

Neo: -

Age: -

 CALM2 1.678 0.718 - - - 0.960 -

Mlig455_035401 {REF} {Length: 3373} {Pfam: EF hand [PF00036.34, score=123.7]; EF-hand domain pair [PF13499.8, score=116.5]; EF-hand domain [PF13405.8, score=97.6]; EF-hand domain pair [PF13833.8, score=94.4]; EF hand [PF13202.8, score=80.0]; EF-hand domain [PF14658.8, score=37.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=34.6]; Dockerin type I domain [PF00404.20, score=29.0]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=28.8]; Tellurite resistance protein TerB [PF05099.15, score=28.5]; Caleosin related protein [PF05042.15, score=22.5]; Uncharacterized conserved protein (DUF2267) [PF10025.11, score=20.3]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=199, Expect=4e-65]; ENSG00000160014, CALM3, calmodulin 3, [Score=198, Expect=4e-65]; ENSG00000198668, CALM1, calmodulin 1, [Score=198, Expect=3e-65]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=198, Expect=3e-65]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=198, Expect=3e-65]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=198, Expect=3e-65]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=198, Expect=1e-65]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=198, Expect=1e-65]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=198, Expect=1e-65]} {RNA1509_38582} {RNA1310_34290, RNA1509_38582} {RNA1509_38582, RNA815_9046}

Mlig455_061039 {REF} {Length: 2458} {Pfam: EF hand [PF00036.34, score=123.7]; EF-hand domain pair [PF13499.8, score=116.5]; EF-hand domain [PF13405.8, score=97.6]; EF-hand domain pair [PF13833.8, score=94.4]; EF hand [PF13202.8, score=80.0]; EF-hand domain [PF14658.8, score=37.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=34.6]; Dockerin type I domain [PF00404.20, score=29.0]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=28.8]; Tellurite resistance protein TerB [PF05099.15, score=28.5]; Caleosin related protein [PF05042.15, score=22.5]; Uncharacterized conserved protein (DUF2267) [PF10025.11, score=20.3]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=199, Expect=4e-65]; ENSG00000160014, CALM3, calmodulin 3, [Score=198, Expect=4e-65]; ENSG00000198668, CALM1, calmodulin 1, [Score=198, Expect=3e-65]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=198, Expect=3e-65]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=198, Expect=3e-65]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=198, Expect=3e-65]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=198, Expect=1e-65]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=198, Expect=1e-65]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=198, Expect=1e-65]} {RNA1509_38582} {RNA1310_34290} {RNA815_9046}
10. MligTC455_12312 158 3.3 Mlig455_020134, Mlig455_045030

Neo: -

Age: -

 SYT7 0.989 - - - - 0.989 -

Mlig455_020134 {REF} {Length: 2000} {Pfam: C2 domain [PF00168.32, score=69.8]} {Human: ENSG00000011347, SYT7, synaptotagmin 7, [Score=130, Expect=1e-31]} {Mouse: ENSMUSG00000024743, Syt7, synaptotagmin VII, [Score=119, Expect=2e-28]; ENSMUSG00000062542, Syt9, synaptotagmin IX, [Score=116, Expect=1e-27]; ENSMUSG00000026452, Syt2, synaptotagmin II, [Score=116, Expect=8e-28]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [Score=157, Expect=5e-42]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=116, Expect=3e-28]} {Smed: dd_Smed_v6_4222_0_1, dd_Smed_v6_4222_0_1, [Score=115, Expect=2e-28]} {RNA1509_46689} {RNA1310_12025} {RNA815_31022}

Mlig455_045030 {REF} {Length: 3640} {Pfam: C2 domain [PF00168.32, score=110.2]} {Human: ENSG00000011347, SYT7, synaptotagmin 7, [Score=169, Expect=6e-45]; ENSG00000143858, SYT2, synaptotagmin 2, [Score=164, Expect=9e-45]; ENSG00000170743, SYT9, synaptotagmin 9, [Score=163, Expect=6e-44]} {Mouse: ENSMUSG00000026452, Syt2, synaptotagmin II, [Score=164, Expect=7e-45]; ENSMUSG00000062542, Syt9, synaptotagmin IX, [Score=164, Expect=2e-44]; ENSMUSG00000024743, Syt7, synaptotagmin VII, [Score=158, Expect=9e-42]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [RH, Score=202, Expect=2e-58]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=153, Expect=6e-41]} {Smed: dd_Smed_v6_4222_0_1, dd_Smed_v6_4222_0_1, [Score=160, Expect=5e-44]} {RNA1509_46689} {RNA1310_12025} {RNA815_31022}
11. MligTC455_34332 28 0.59 Mlig455_005058

Neo: -

Age: -

 NKX3-2 0.983 - - - - 0.983 - Mlig455_005058 {REF} {Length: 1884} {Pfam: Homeodomain [PF00046.31, score=68.8]} {Human: ENSG00000109705, NKX3-2, NK3 homeobox 2, [RH, Score=118, Expect=4e-29]} {Mouse: ENSMUSG00000049691, Nkx3-2, NK3 homeobox 2, [RH, Score=118, Expect=2e-29]} {Dmel: FBgn0004862, bap, bagpipe, [RH, Score=115, Expect=7e-28]} {Celegans: WBGene00003377, mls-2, Mesodermal Lineage Specification, [Score=90.9, Expect=7e-20]} {Smed: dd_Smed_v6_34285_0_1, dd_Smed_v6_34285_0_1, [RH, Score=94.0, Expect=4e-23]}
12. MligTC455_17684 157 3.26 Mlig455_041455

Neo: Irradiation

Age: Up-Down-Down

 ASPG 0.981 - - - - 0.981 - Mlig455_041455 {REF} {Length: 5938} {TRANSSPLICED} {Pfam: Asparaginase, N-terminal [PF00710.22, score=202.1]; Glutaminase/Asparaginase C-terminal domain [PF17763.3, score=84.6]; Ankyrin repeats (many copies) [PF13857.8, score=64.3]; Ankyrin repeats (3 copies) [PF12796.9, score=59.0]; Ankyrin repeats (many copies) [PF13637.8, score=54.0]; Ankyrin repeat [PF13606.8, score=43.8]; Ankyrin repeat [PF00023.32, score=35.8]} {Human: ENSG00000166183, ASPG, asparaginase, [Score=346, Expect=7e-110]} {Mouse: ENSMUSG00000037686, Aspg, asparaginase, [Score=340, Expect=9e-108]} {Dmel: FBgn0029689, CG6428, [RH, Score=439, Expect=2e-145]} {Celegans: WBGene00007756, C27A7.5, [Score=412, Expect=1e-134]} {Smed: dd_Smed_v6_7816_0_1, dd_Smed_v6_7816_0_1, [RH, Score=426, Expect=7e-140]} {RNA1509_11582, RNA1509_16816, RNA1509_8667} {RNA1310_8678, RNA1509_16816, RNA1509_8667} {RNA1509_16816, RNA1509_8667, RNA815_6302}
13. MligTC455_34333 29 0.59 Mlig455_005256

Neo: -

Age: -

 NKX3-2 0.977 - - - - 0.977 - Mlig455_005256 {REF} {Length: 1971} {Pfam: Homeodomain [PF00046.31, score=68.8]} {Human: ENSG00000109705, NKX3-2, NK3 homeobox 2, [RH, Score=119, Expect=3e-29]} {Mouse: ENSMUSG00000049691, Nkx3-2, NK3 homeobox 2, [RH, Score=119, Expect=2e-29]} {Dmel: FBgn0004862, bap, bagpipe, [RH, Score=115, Expect=5e-28]} {Celegans: WBGene00003377, mls-2, Mesodermal Lineage Specification, [Score=89.7, Expect=2e-19]} {Smed: dd_Smed_v6_34285_0_1, dd_Smed_v6_34285_0_1, [RH, Score=94.0, Expect=4e-23]}
14. MligTC455_19114 79 1.64 Mlig455_045107

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.813

 0.974 - - - - 0.974 - Mlig455_045107 {REF} {Length: 1513} {Pfam: F5/8 type C domain [PF00754.27, score=20.0]} {RNA1509_57504} {RNA1310_27303.2} {RNA815_32964}
15. MligTC455_29693 81 1.69 Mlig455_032201, Mlig455_036011, Mlig455_054134

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.250

 ANKRD50 0.974 - - - - - 0.974

Mlig455_032201 {REF} {Length: 3871} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=42.5]; Mab-21 protein [PF03281.16, score=40.7]; Ankyrin repeats (many copies) [PF13637.8, score=40.2]; Ankyrin repeats (many copies) [PF13857.8, score=39.0]; Ankyrin repeat [PF13606.8, score=34.3]; Ankyrin repeat [PF00023.32, score=30.5]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=65.9, Expect=2e-10]; ENSG00000170921, TANC2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=63.9, Expect=9e-10]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=66.6, Expect=8e-11]} {Dmel: FBgn0041096, rols, rolling pebbles, [Score=60.8, Expect=3e-09]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=55.5, Expect=2e-07]} {Smed: dd_Smed_v6_12936_0_1, dd_Smed_v6_12936_0_1, [Score=60.1, Expect=4e-09]} {RNA1509_27730} {RNA1310_21755.1} {RNA815_2426.1}

Mlig455_036011 {REF} {Length: 1929} {Pfam: Mab-21 protein [PF03281.16, score=39.7]} {RNA1509_27730} {RNA1310_4721} {RNA815_5358.1}

Mlig455_054134 {REF} {Length: 2699} {RNA1509_26281} {RNA1310_31514} {RNA815_5358.1}
16. MligTC455_50171 151 3.14 Mlig455_065462

Neo: -

Age: logFC(26M/2M)=0.548

Region-specific R2: 5.212

Region-enriched R2: 5.063/0.00089

Regeneration-downregulated R2: -2.783

Regeneration-depleted R2: -2.783

 SCNN1A 0.973 - - - - 0.973 - Mlig455_065462 {REF} {Length: 3905} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=185.3]} {Human: ENSG00000111319, SCNN1A, sodium channel epithelial 1 alpha subunit, [Score=60.1, Expect=9e-09]} {Mouse: ENSMUSG00000030340, Scnn1a, sodium channel, nonvoltage-gated 1 alpha, [Score=67.0, Expect=5e-11]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=92.8, Expect=1e-19]} {Smed: dd_Smed_v6_16959_0_1, dd_Smed_v6_16959_0_1, [Score=275, Expect=3e-83]} {RNA1509_60030} {RNA1310_56761} {RNA815_31877.1}
17. MligTC455_20294 341 7.11 Mlig455_007896, Mlig455_008003

Neo: -

Age: Up-Down-Down

Region-enriched R8: 3.032/0.04842

 LRRK2 0.972 - - - - 0.972 -

Mlig455_007896 {REF} {Length: 11344} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=164.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=71.6]; TIR domain [PF13676.8, score=57.4]; Leucine rich repeat [PF13855.8, score=43.0]; Ras family [PF00071.24, score=38.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=24.8]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=167, Expect=3e-40]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=166, Expect=5e-40]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=145, Expect=7e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=125, Expect=4e-28]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=723, Expect=0.0]} {RNA1509_8727} {RNA1310_292.1, RNA1509_8727} {RNA1509_8727, RNA815_1320}

Mlig455_008003 {REF} {Length: 11209} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=160.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=72.4]; TIR domain [PF13676.8, score=59.5]; Leucine rich repeat [PF13855.8, score=45.2]; Ras family [PF00071.24, score=39.6]; Leucine Rich repeats (2 copies) [PF12799.9, score=28.4]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=167, Expect=1e-40]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=163, Expect=1e-39]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=145, Expect=4e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=120, Expect=1e-26]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=686, Expect=0.0]} {RNA1509_8727} {RNA1310_292.1} {RNA815_1320}
18. MligTC455_45719 94 1.96 Mlig455_056535

Neo: -

Age: -

 CHRNA6 0.97 - - - - 0.970 - Mlig455_056535 {REF} {Length: 2532} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=102.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=75.5]} {Human: ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=127, Expect=1e-31]; ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=125, Expect=4e-31]} {Mouse: ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=125, Expect=5e-31]; ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=120, Expect=1e-29]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=117, Expect=4e-28]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=125, Expect=3e-31]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=122, Expect=4e-30]} {RNA1509_7752} {RNA1310_37530} {RNA815_18433}
19. MligTC455_00977 36 0.74 Mlig455_030564

Neo: -

Age: -

 0.969 - - - - - 0.969 Mlig455_030564 {REF} {Length: 420}
20. MligTC455_10416 765 15.93 Mlig455_008958

Neo: -

Age: -

Region-enriched R8: 1.474/0.04842

 0.969 - - - - - 0.969 Mlig455_008958 {REF} {Length: 515} {NoTransDecoderORF} {RNA1310_120997} {RNA815_53530}
21. MligTC455_19193 147 3.07 Mlig455_007213

Neo: -

Age: -

 BFAR 0.968 - - - - - 0.968 Mlig455_007213 {REF} {Length: 2792} {Pfam: Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=31.1]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=30.1]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=30.0]; zinc finger of C3HC4-type, RING [PF15227.8, score=29.7]; RING-type zinc-finger [PF13445.8, score=29.4]; Ring finger domain [PF13639.8, score=27.0]; zinc-RING finger domain [PF14634.8, score=25.5]; Prokaryotic RING finger family 4 [PF14447.8, score=22.2]; RING-H2 zinc finger domain [PF12678.9, score=19.9]} {Human: ENSG00000275618, BFAR, bifunctional apoptosis regulator, [RH, Score=49.3, Expect=7e-07]; ENSG00000103429, BFAR, bifunctional apoptosis regulator, [RH, Score=49.3, Expect=7e-07]} {Mouse: ENSMUSG00000022684, Bfar, bifunctional apoptosis regulator, [RH, Score=52.8, Expect=1e-08]; ENSMUSG00000057596, Trim30d, tripartite motif-containing 30D, [RH, Score=50.8, Expect=2e-07]} {Smed: dd_Smed_v6_10019_0_1, dd_Smed_v6_10019_0_1, [Score=46.2, Expect=2e-06]} {RNA1509_42543, RNA1509_53684} {RNA1310_39360, RNA1509_42543} {RNA1509_42543, RNA815_20181}
22. MligTC455_36887 1030 21.45 Mlig455_004357, Mlig455_028085, Mlig455_028098, Mlig455_028220, Mlig455_046388

Neo: Int S/G2/M

Age: Down-Down-Down, logFC(26M/2M)=-0.994

Region-enriched R4: 2.550/0.00002

 0.968 - - - - 0.968 -

Mlig455_004357 {REF} {Length: 1577} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_6383} {RNA1310_24468.1} {RNA815_17487.1}

Mlig455_028085 {REF} {Length: 1588} {TRANSSPLICED} {RNA1509_6383} {RNA1310_24468.1} {RNA815_17487.1}

Mlig455_028098 {REF} {Length: 946} {TRANSSPLICED} {RNA1509_6383} {RNA1310_41531.1} {RNA815_17487.1}

Mlig455_028220 {REF} {Length: 937} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_6383} {RNA1310_41531.1} {RNA815_17487.1}

Mlig455_046388 {REF} {Length: 886} {TRANSSPLICED} {RNA1509_6383} {RNA1310_24468.1} {RNA815_17487.1}
23. MligTC455_18944 44 0.91 Mlig455_029192

Neo: -

Age: -

 WNT3A 0.966 - - - - 0.966 - Mlig455_029192 {REF} {Length: 1352} {Pfam: wnt family [PF00110.21, score=50.0]} {Human: ENSG00000154342, WNT3A, Wnt family member 3A, [Score=50.8, Expect=3e-07]} {Mouse: ENSMUSG00000029671, Wnt16, wingless-type MMTV integration site family, member 16, [Score=51.2, Expect=9e-08]; ENSMUSG00000009900, Wnt3a, wingless-type MMTV integration site family, member 3A, [Score=50.8, Expect=2e-07]} {RNA1310_39214} {RNA815_58383}
24. MligTC455_32796 106 2.21 Mlig455_059824

Neo: Int S/G2/M

Age: -

 0.966 - - - - 0.966 - Mlig455_059824 {REF} {Length: 1634} {TRANSSPLICED} {RNA1509_48912} {RNA1310_29994} {RNA815_2705}
25. MligTC455_48489 332 6.91 Mlig455_013844

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.459

 MX2 0.966 - - - - 0.966 - Mlig455_013844 {REF} {Length: 3484} {Pfam: Dynamin family [PF00350.25, score=88.9]; Dynamin central region [PF01031.22, score=31.1]; Dynamin GTPase effector domain [PF02212.20, score=25.1]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=113, Expect=1e-25]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=95.5, Expect=5e-20]; ENSMUSG00000000386, Mx1, MX dynamin-like GTPase 1, [Score=92.4, Expect=3e-20]} {Dmel: FBgn0261276, Opa1, Optic atrophy 1, [Score=72.0, Expect=1e-12]} {Celegans: WBGene00001134, eat-3, [Score=76.3, Expect=4e-14]} {Smed: dd_Smed_v6_8582_0_1, dd_Smed_v6_8582_0_1, [Score=84.3, Expect=5e-19]} {RNA1509_6344} {RNA1310_8723, RNA1509_6344} {RNA1509_6344, RNA815_3559}
26. MligTC455_43363 58 1.22 Mlig455_002291

Neo: -

Age: -

Region-enriched R2: 5.574/0.01843

 0.965 - - - - 0.965 - Mlig455_002291 {REF} {Length: 2912} {TRANSSPLICED} {Smed: dd_Smed_v6_9636_0_1, dd_Smed_v6_9636_0_1, [RH, Score=130, Expect=9e-32]} {RNA1509_37248} {RNA1310_12152.1} {RNA815_8090}
27. MligTC455_47313 364 7.58 Mlig455_058672

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.435

 LUC7L 0.965 - - - - 0.965 - Mlig455_058672 {REF} {Length: 2574} {Pfam: LUC7 N_terminus [PF03194.17, score=239.7]} {Human: ENSG00000007392, LUC7L, LUC7 like, [RH, Score=303, Expect=7e-99]; ENSG00000146963, LUC7L2, LUC7 like 2, pre-mRNA splicing factor, [RH, Score=293, Expect=9e-95]} {Mouse: ENSMUSG00000024188, Luc7l, Luc7-like, [RH, Score=303, Expect=8e-99]; ENSMUSG00000029823, Luc7l2, LUC7-like 2 (S. cerevisiae), [RH, Score=290, Expect=2e-94]} {Dmel: FBgn0036734, CG7564, [RH, Score=306, Expect=2e-99]} {Celegans: WBGene00015207, B0495.8, [RH, Score=161, Expect=2e-45]} {Smed: dd_Smed_v6_4536_0_4, dd_Smed_v6_4536_0_4, [RH, Score=300, Expect=3e-99]} {RNA1509_894} {RNA1310_9024.1} {RNA815_807.1}
28. MligTC455_29682 45 0.93 Mlig455_007255

Neo: -

Age: -

Region-enriched R2: 5.343/0.00895

 0.964 - - - - 0.964 - Mlig455_007255 {REF} {Length: 1636} {NoTransDecoderORF} {RNA1509_16956} {RNA1310_77083} {RNA815_33530}
29. MligTC455_25107 160 3.33 Mlig455_002517, Mlig455_002651

Neo: -

Age: -

 GABRB2 0.963 - - - - - 0.963

Mlig455_002517 {REF} {Length: 3630} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=169.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=153.0]} {Human: ENSG00000145864, GABRB2, gamma-aminobutyric acid type A receptor beta2 subunit, [RH, Score=414, Expect=6e-139]} {Mouse: ENSMUSG00000007653, Gabrb2, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2, [RH, Score=408, Expect=5e-137]} {Dmel: FBgn0010240, Lcch3, Ligand-gated chloride channel homolog 3, [RH, Score=462, Expect=2e-158]} {Celegans: WBGene00001512, gab-1, Gamma-aminobutyric acid receptor subunit beta, [Score=458, Expect=2e-156]} {Smed: dd_Smed_v6_25116_0_1, dd_Smed_v6_25116_0_1, [RH, Score=484, Expect=5e-167]} {RNA1509_47435} {RNA1310_12876.1, RNA1509_47435} {RNA1509_47435, RNA815_12505}

Mlig455_002651 {REF} {Length: 3208} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=169.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=153.8]} {Human: ENSG00000145864, GABRB2, gamma-aminobutyric acid type A receptor beta2 subunit, [RH, Score=413, Expect=6e-139]} {Mouse: ENSMUSG00000007653, Gabrb2, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2, [RH, Score=408, Expect=5e-137]} {Dmel: FBgn0010240, Lcch3, Ligand-gated chloride channel homolog 3, [RH, Score=462, Expect=1e-158]} {Celegans: WBGene00001512, gab-1, Gamma-aminobutyric acid receptor subunit beta, [Score=459, Expect=7e-157]} {Smed: dd_Smed_v6_25116_0_1, dd_Smed_v6_25116_0_1, [RH, Score=484, Expect=5e-167]} {RNA1509_47435} {RNA1310_12876.1} {RNA815_12505}
30. MligTC455_41883 85 1.77 Mlig455_012612

Neo: -

Age: -

 ANKRD50 0.963 - - - - - 0.963 Mlig455_012612 {REF} {Length: 7141} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=77.8]; Ankyrin repeats (many copies) [PF13637.8, score=63.2]; Ankyrin repeats (many copies) [PF13857.8, score=53.8]; Ankyrin repeat [PF13606.8, score=46.8]; Mab-21 protein [PF03281.16, score=41.3]; Ankyrin repeat [PF00023.32, score=37.7]; Helix-turn-helix domain [PF13560.8, score=18.9]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=86.3, Expect=2e-16]; ENSG00000170921, TANC2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=83.6, Expect=1e-15]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=87.4, Expect=6e-17]} {Dmel: FBgn0041096, rols, rolling pebbles, [Score=91.7, Expect=2e-18]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=64.7, Expect=3e-10]} {Smed: dd_Smed_v6_6779_0_1, dd_Smed_v6_6779_0_1, [Score=89.7, Expect=5e-18]} {RNA1509_27676, RNA1509_27730} {RNA1310_22442, RNA1509_27676} {RNA1509_27676, RNA815_2426.1}
31. MligTC455_43534 34 0.71 Mlig455_030976

Neo: -

Age: -

 0.963 - - - - 0.963 - Mlig455_030976 {REF} {Length: 1067} {RNA1310_40722} {RNA815_46396}
32. MligTC455_28630 190 3.95 Mlig455_062402

Neo: -

Age: logFC(26M/2M)=0.419

 COG1 0.962 - - - - - 0.962 Mlig455_062402 {REF} {Length: 3965} {TRANSSPLICED} {Pfam: Vps51/Vps67 [PF08700.13, score=50.7]} {Human: ENSG00000166685, COG1, component of oligomeric golgi complex 1, [RH, Score=185, Expect=1e-47]} {Mouse: ENSMUSG00000018661, Cog1, component of oligomeric golgi complex 1, [RH, Score=186, Expect=7e-48]} {Dmel: FBgn0037998, Cog1, Component of oligomeric golgi complex 1, [RH, Score=83.2, Expect=6e-16]} {Smed: dd_Smed_v6_5278_0_1, dd_Smed_v6_5278_0_1, [RH, Score=108, Expect=5e-24]} {RNA1509_40350} {RNA1310_3020} {RNA815_7633}
33. MligTC455_32376 774 16.13 Mlig455_042047

Neo: -

Age: -

 0.961 - - - - - 0.961 Mlig455_042047 {REF} {Length: 5768} {Pfam: BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=31.8]} {RNA1509_13039, RNA1509_16800, RNA1509_21905, RNA1509_27318, RNA1509_33932, RNA1509_7422} {RNA1310_9687, RNA1509_13039, RNA1509_16800, RNA1509_21905, RNA1509_27318, RNA1509_33932, RNA1509_7422} {RNA1509_13039, RNA1509_16800, RNA1509_21905, RNA1509_27318, RNA1509_33932, RNA1509_7422, RNA815_5090}
34. MligTC455_36614 481 10.01 Mlig455_002969, Mlig455_049084

Neo: -

Age: Up-Down-Down

 RNF13 0.961 - - - - 0.961 -

Mlig455_002969 {REF} {Length: 682} {Pfam: Hydrophobic surface binding protein A [PF12296.10, score=21.2]; Flocculin repeat [PF00624.20, score=19.6]} {RNA1310_44296} {RNA815_35577}

Mlig455_049084 {REF} {Length: 3354} {TRANSSPLICED} {Pfam: RING-like zinc finger [PF17123.7, score=47.7]; Ring finger domain [PF13639.8, score=46.8]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=32.1]; zinc-RING finger domain [PF14634.8, score=26.6]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=25.5]; RING-type zinc-finger [PF13445.8, score=25.2]; RING-H2 zinc finger domain [PF12678.9, score=25.1]; Prokaryotic RING finger family 4 [PF14447.8, score=24.8]; PA domain [PF02225.24, score=23.2]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=19.6]} {Human: ENSG00000082996, RNF13, ring finger protein 13, [RH, Score=192, Expect=2e-56]} {Mouse: ENSMUSG00000036503, Rnf13, ring finger protein 13, [RH, Score=195, Expect=8e-58]} {Dmel: FBgn0037442, godzilla, godzilla E3 ubiquitin protein ligase, [RH, Score=152, Expect=1e-40]} {Celegans: WBGene00007666, C18B12.4, [RH, Score=140, Expect=1e-36]} {Smed: dd_Smed_v6_10741_0_2, dd_Smed_v6_10741_0_2, [RH, Score=84.7, Expect=8e-18]} {RNA1509_13438} {RNA1310_21318.1} {RNA815_6447}
35. MligTC455_41028 108 2.26 Mlig455_033278

Neo: -

Age: -

 0.961 - - - - 0.961 - Mlig455_033278 {REF} {Length: 1134} {Pfam: PAN domain [PF00024.28, score=19.4]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=9e-14]} {RNA1310_31986} {RNA815_17816.2}
36. MligTC455_49842 391 8.14 Mlig455_030095

Neo: -

Age: Down-Up-Up

 0.96 - - - - 0.960 - Mlig455_030095 {REF} {Length: 2464} {TRANSSPLICED} {RNA1509_54601} {RNA1310_30894.2, RNA1509_54601} {RNA1509_54601, RNA815_35555}
37. MligTC455_02117 19 0.4 Mlig455_065174

Neo: -

Age: -

 0.959 - - - - 0.959 - Mlig455_065174 {REF} {Length: 1623}
38. MligTC455_38108 59 1.23 Mlig455_029176, Mlig455_030240

Neo: -

Age: -

 GABRR2 0.959 - - - - - 0.959

Mlig455_029176 {REF} {Length: 1196} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=83.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=65.2]} {Human: ENSG00000111886, GABRR2, gamma-aminobutyric acid type A receptor rho2 subunit, [Score=152, Expect=1e-40]; ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=150, Expect=5e-40]} {Mouse: ENSMUSG00000023267, Gabrr2, gamma-aminobutyric acid (GABA) C receptor, subunit rho 2, [Score=148, Expect=2e-39]; ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=147, Expect=4e-39]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=145, Expect=2e-38]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=145, Expect=1e-38]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=143, Expect=9e-38]; ENSMUSG00000028280, Gabrr1, gamma-aminobutyric acid (GABA) C receptor, subunit rho 1, [Score=142, Expect=3e-37]} {Dmel: FBgn0024963, GluClalpha, [Score=144, Expect=3e-38]} {Celegans: WBGene00001592, glc-2, Glutamate-gated chloride channel subunit beta, [Score=156, Expect=4e-43]} {Smed: dd_Smed_v6_14811_0_1, dd_Smed_v6_14811_0_1, [Score=186, Expect=2e-54]} {RNA1310_127675}

Mlig455_030240 {REF} {Length: 2005} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=83.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=65.2]} {Human: ENSG00000111886, GABRR2, gamma-aminobutyric acid type A receptor rho2 subunit, [Score=152, Expect=1e-40]; ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=150, Expect=5e-40]} {Mouse: ENSMUSG00000023267, Gabrr2, gamma-aminobutyric acid (GABA) C receptor, subunit rho 2, [Score=148, Expect=2e-39]; ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=147, Expect=4e-39]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=145, Expect=2e-38]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=145, Expect=1e-38]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=143, Expect=9e-38]; ENSMUSG00000028280, Gabrr1, gamma-aminobutyric acid (GABA) C receptor, subunit rho 1, [Score=142, Expect=3e-37]} {Dmel: FBgn0024963, GluClalpha, [Score=144, Expect=3e-38]} {Celegans: WBGene00001592, glc-2, Glutamate-gated chloride channel subunit beta, [Score=156, Expect=4e-43]} {Smed: dd_Smed_v6_14811_0_1, dd_Smed_v6_14811_0_1, [Score=186, Expect=2e-54]} {RNA1310_127675} {RNA815_24496}
39. MligTC455_39850 188 3.91 Mlig455_049688

Neo: Germline

Age: Up-Down-Down

Region-enriched R4: 2.276/0.03369

 NUB1 0.959 - - - - 0.959 - Mlig455_049688 {REF} {Length: 3207} {TRANSSPLICED} {Pfam: UBA/TS-N domain [PF00627.33, score=47.4]; Ubiquitin-like domain [PF18037.3, score=31.6]; Ubiquitin family [PF00240.25, score=20.2]} {Human: ENSG00000013374, NUB1, negative regulator of ubiquitin like proteins 1, [Score=186, Expect=3e-50]} {Mouse: ENSMUSG00000028954, Nub1, negative regulator of ubiquitin-like proteins 1, [Score=180, Expect=3e-48]} {Dmel: FBgn0039343, CG5111, [Score=256, Expect=4e-76]} {Smed: dd_Smed_v6_3402_0_1, dd_Smed_v6_3402_0_1, [RH, Score=174, Expect=8e-47]} {RNA1509_17867, RNA1509_9830} {RNA1310_7816.2, RNA1509_17867, RNA1509_9830} {RNA1509_17867, RNA1509_9830, RNA815_3803}
40. MligTC455_19537 88 1.84 Mlig455_003807, Mlig455_033281

Neo: -

Age: -

 0.958 - - - - 0.958 -

Mlig455_003807 {REF} {Length: 2979} {RNA1509_47157} {RNA1310_48795} {RNA815_29674}

Mlig455_033281 {REF} {Length: 441} {NoTransDecoderORF} {RNA1310_57478} {RNA815_29674}
41. MligTC455_36736 652 13.59 Mlig455_019400, Mlig455_059073

Neo: -

Age: Down-Up-Down

Region-enriched R4: 2.387/0.01731

 PLCL2 0.958 - - - - 0.958 -

Mlig455_019400 {REF} {Length: 5099} {TRANSSPLICED} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=174.7]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=102.7]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=56.2]; C2 domain [PF00168.32, score=54.1]; Pleckstrin homology domain [PF16457.7, score=29.3]} {Human: ENSG00000284017, PLCL2, phospholipase C like 2, [RH, Score=814, Expect=0.0]; ENSG00000154822, PLCL2, phospholipase C like 2, [RH, Score=814, Expect=0.0]} {Mouse: ENSMUSG00000038910, Plcl2, phospholipase C-like 2, [RH, Score=809, Expect=0.0]} {Dmel: FBgn0004611, Plc21C, Phospholipase C at 21C, [Score=194, Expect=5e-50]} {Celegans: WBGene00004045, pll-1, Phosphoinositide phospholipase C, [RH, Score=719, Expect=0.0]} {Smed: dd_Smed_v6_6102_0_1, dd_Smed_v6_6102_0_1, [RH, Score=935, Expect=0.0]} {RNA1509_8212} {RNA1310_929.2, RNA1509_8212} {RNA1509_8212, RNA815_5686}

Mlig455_059073 {REF} {Length: 5182} {TRANSSPLICED} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=174.7]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=102.7]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=56.2]; C2 domain [PF00168.32, score=54.1]; Pleckstrin homology domain [PF16457.7, score=29.3]} {Human: ENSG00000284017, PLCL2, phospholipase C like 2, [RH, Score=814, Expect=0.0]; ENSG00000154822, PLCL2, phospholipase C like 2, [RH, Score=814, Expect=0.0]} {Mouse: ENSMUSG00000038910, Plcl2, phospholipase C-like 2, [RH, Score=809, Expect=0.0]} {Dmel: FBgn0004611, Plc21C, Phospholipase C at 21C, [Score=194, Expect=5e-50]} {Celegans: WBGene00004045, pll-1, Phosphoinositide phospholipase C, [RH, Score=719, Expect=0.0]} {Smed: dd_Smed_v6_6102_0_1, dd_Smed_v6_6102_0_1, [RH, Score=935, Expect=0.0]} {RNA1509_60150, RNA1509_8212} {RNA1310_929.2, RNA1509_60150} {RNA1509_60150, RNA815_5686}
42. MligTC455_33203 151 3.15 Mlig455_033692, Mlig455_050137

Neo: -

Age: -

 0.957 - - - - 0.957 -

Mlig455_033692 {REF} {Length: 1036} {NoTransDecoderORF} {RNA1509_59732} {RNA1310_52952} {RNA815_34163}

Mlig455_050137 {REF} {Length: 1740} {NoTransDecoderORF} {RNA1509_59732, RNA1509_60018} {RNA1310_63905.1, RNA1509_59732, RNA1509_60018} {RNA1509_59732, RNA1509_60018, RNA815_34163}
43. MligTC455_49348 106 2.22 Mlig455_042275

Neo: -

Age: -

 0.957 - - - - - 0.957 Mlig455_042275 {REF} {Length: 1278} {NoTransDecoderORF} {RNA1509_58228} {RNA1310_48769.2} {RNA815_29333}
44. MligTC455_08884 27 0.57 Mlig455_053794, Mlig455_068544

Neo: -

Age: -

 SCNN1B 0.956 - - - - 0.956 -

Mlig455_053794 {REF} {Length: 1923} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=170.4]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=73.9, Expect=3e-13]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [Score=72.4, Expect=6e-13]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=62.4, Expect=6e-10]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=86.3, Expect=1e-17]} {RNA1509_31312} {RNA1310_35950} {RNA815_20662}

Mlig455_068544 {REF} {Length: 2256} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=170.9]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=73.9, Expect=4e-13]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [Score=72.4, Expect=7e-13]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=62.0, Expect=7e-10]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=85.1, Expect=3e-17]} {RNA1509_31137} {RNA1310_35950} {RNA815_20662}
45. MligTC455_13935 206 4.3 Mlig455_019165

Neo: -

Age: Up-Up-Down

Region-enriched R2: 3.248/0.00981

 0.956 - - - - 0.956 - Mlig455_019165 {REF} {Length: 3759} {Pfam: Major Facilitator Superfamily [PF07690.18, score=92.7]; MFS/sugar transport protein [PF13347.8, score=41.5]; MFS_1 like family [PF12832.9, score=37.3]; PUCC protein [PF03209.17, score=28.6]} {Smed: dd_Smed_v6_8550_0_1, dd_Smed_v6_8550_0_1, [RH, Score=441, Expect=4e-150]} {RNA1509_28461, RNA1509_55131} {RNA1310_7716, RNA1509_28461, RNA1509_55131} {RNA1509_28461, RNA1509_55131, RNA815_2811.1}
46. MligTC455_13696 163 3.4 Mlig455_060358

Neo: -

Age: logFC(26M/2M)=-0.669

 0.955 - - - - - 0.955 Mlig455_060358 {REF} {Length: 1184} {RNA1310_27239} {RNA815_56495}
47. MligTC455_54194 156 3.25 Mlig455_066828

Neo: -

Age: logFC(26M/2M)=-0.485

 0.955 - - - - - 0.955 Mlig455_066828 {REF} {Length: 1460} {RNA1509_54236} {RNA1310_18757.1, RNA1509_54236} {RNA1509_54236, RNA815_5768.1}
48. MligTC455_21526 556 11.59 Mlig455_052730

Neo: -

Age: Up-Down-Down

 SLC26A5 0.954 - - - - 0.954 - Mlig455_052730 {REF} {Length: 4391} {Pfam: Sulfate permease family [PF00916.22, score=264.3]; STAS domain [PF01740.23, score=80.1]} {Human: ENSG00000170615, SLC26A5, solute carrier family 26 member 5, [Score=340, Expect=3e-103]} {Mouse: ENSMUSG00000029015, Slc26a5, solute carrier family 26, member 5, [Score=340, Expect=2e-103]} {Dmel: FBgn0036770, Prestin, [Score=234, Expect=4e-65]} {Celegans: WBGene00013963, sulp-8, Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family, [Score=229, Expect=2e-64]} {Smed: dd_Smed_v6_8150_0_1, dd_Smed_v6_8150_0_1, [Score=389, Expect=3e-121]} {RNA1509_2157, RNA1509_36681, RNA1509_45989, RNA1509_52408} {RNA1310_11012, RNA1509_2157, RNA1509_36681, RNA1509_45989, RNA1509_52408} {RNA1509_2157, RNA1509_36681, RNA1509_45989, RNA1509_52408, RNA815_1075.1}
49. MligTC455_12919 24 0.5 Mlig455_012237

Neo: -

Age: -

Region-enriched R4: 8.303/0.00009

 0.953 - - - - 0.953 - Mlig455_012237 {REF} {Length: 1410} {TRANSSPLICED} {RNA1310_38823} {RNA815_30372}
50. MligTC455_31908 1011 21.07 Mlig455_018835, Mlig455_018847, Mlig455_019651, Mlig455_028859, Mlig455_029316, Mlig455_053198, Mlig455_055008, Mlig455_057607, Mlig455_059271, Mlig455_059778, Mlig455_060484, Mlig455_067924

Neo: -

Age: Up-Down-Down

 0.952 - - - - 0.952 -

Mlig455_018835 {REF} {Length: 972} {RNA1509_59141} {RNA1310_2129.2} {RNA815_36885}

Mlig455_018847 {REF} {Length: 728} {RNA1509_59141} {RNA1310_6711.2} {RNA815_36885}

Mlig455_019651 {REF} {Length: 3110} {RNA1509_28299} {RNA1310_2129.1} {RNA815_8926}

Mlig455_028859 {REF} {Length: 4548} {RNA1509_6194} {RNA1310_6711.1} {RNA815_15794}

Mlig455_029316 {REF} {Length: 8604} {RNA1509_6194} {RNA1310_1675.1} {RNA815_2266}

Mlig455_053198 {REF} {Length: 9565} {RNA1509_6194} {RNA1310_1675.1} {RNA815_2266}

Mlig455_055008 {REF} {Length: 9883} {RNA1509_6194} {RNA1310_1675.1} {RNA815_2266}

Mlig455_057607 {REF} {Length: 9892} {RNA1509_6194} {RNA1310_1675.1} {RNA815_2266}

Mlig455_059271 {REF} {Length: 9896} {RNA1509_6194} {RNA1310_1675.1} {RNA815_2266}

Mlig455_059778 {REF} {Length: 9869} {RNA1509_47689, RNA1509_6194} {RNA1310_2129.1, RNA1509_47689} {RNA1509_47689, RNA815_2266}

Mlig455_060484 {REF} {Length: 5720} {RNA1509_6194} {RNA1310_2129.1} {RNA815_8926}

Mlig455_067924 {REF} {Length: 9889} {RNA1509_6194} {RNA1310_1675.1} {RNA815_2266}
51. MligTC455_09828 80 1.67 Mlig455_052764

Neo: -

Age: -

 0.951 - - - - - 0.951 Mlig455_052764 {REF} {Length: 1206} {NoTransDecoderORF} {RNA1310_17510.1} {RNA815_9674}
52. MligTC455_22910 103 2.14 Mlig455_040130

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.273

 TMEM214 0.951 - - - - 0.951 - Mlig455_040130 {REF} {Length: 3719} {Pfam: TMEM214, C-terminal, caspase 4 activator [PF10151.11, score=88.6]} {Human: ENSG00000119777, TMEM214, transmembrane protein 214, [RH, Score=58.9, Expect=2e-08]} {Mouse: ENSMUSG00000038828, Tmem214, transmembrane protein 214, [RH, Score=61.2, Expect=3e-09]} {RNA1509_7642} {RNA1310_10501} {RNA815_16505}
53. MligTC455_46367 535 11.15 Mlig455_066511

Neo: -

Age: logFC(26M/2M)=-0.381

 0.95 - - - - - 0.950 Mlig455_066511 {REF} {Length: 4295} {RNA1509_38263, RNA1509_51270} {RNA1310_46161.1, RNA1509_51270} {RNA1509_51270, RNA815_23835}

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