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Results for MligTC455_37847

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_37847 70 1.46 Mlig455_049316

Neo: -

Age: -

SLC22A15 Mlig455_049316 {REF} {Length: 2542} {Pfam: Sugar (and other) transporter [PF00083.26, score=46.4]} {Human: ENSG00000163393, SLC22A15, solute carrier family 22 member 15, [Score=114, Expect=9e-28]; ENSG00000112499, SLC22A2, solute carrier family 22 member 2, [Score=113, Expect=2e-27]; ENSG00000146477, SLC22A3, solute carrier family 22 member 3, [Score=111, Expect=1e-26]} {Mouse: ENSMUSG00000023829, Slc22a1, solute carrier family 22 (organic cation transporter), member 1, [Score=118, Expect=3e-29]; ENSMUSG00000033147, Slc22a15, solute carrier family 22 (organic anion/cation transporter), member 15, [Score=115, Expect=3e-28]; ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=114, Expect=1e-27]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=132, Expect=3e-34]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=91.3, Expect=4e-20]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=114, Expect=3e-28]} {RNA1509_46580} {RNA1310_33722} {RNA815_7677}

Cumulative graph for MligTC455_37847

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -3.984 1.64 0.47712 1.00000
RegionR2 2.908 1.64 0.01730 0.14017
RegionR3 -0.935 1.64 0.98755 1.00000
RegionR4 -0.537 1.64 0.96398 1.00000
RegionR5 0.006 1.64 0.86013 1.00000
RegionR6 0.69 1.64 0.55003 1.00000
RegionR7 1.01 1.64 0.46282 1.00000
RegionR8 0.842 1.64 0.60450 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.049 1.64 0.99998 1.00000
RegenerationR2 -0.618 1.64 0.30862 0.74899
RegenerationR3 1.142 1.64 0.29163 0.72360
RegenerationR4 -0.522 1.64 0.62264 0.92153
RegenerationR5 -0.419 1.64 0.63664 0.92534
RegenerationR6 -2.167 1.64 0.07559 0.34357
RegenerationBL -4.459 1.64 0.07319 0.31565
RegenerationTP -1.537 1.64 0.34366 0.78648


Genes with expression patterns similar to MligTC455_37847

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_37847 70 1.46 Mlig455_049316

Neo: -

Age: -

SLC22A15 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_049316 {REF} {Length: 2542} {Pfam: Sugar (and other) transporter [PF00083.26, score=46.4]} {Human: ENSG00000163393, SLC22A15, solute carrier family 22 member 15, [Score=114, Expect=9e-28]; ENSG00000112499, SLC22A2, solute carrier family 22 member 2, [Score=113, Expect=2e-27]; ENSG00000146477, SLC22A3, solute carrier family 22 member 3, [Score=111, Expect=1e-26]} {Mouse: ENSMUSG00000023829, Slc22a1, solute carrier family 22 (organic cation transporter), member 1, [Score=118, Expect=3e-29]; ENSMUSG00000033147, Slc22a15, solute carrier family 22 (organic anion/cation transporter), member 15, [Score=115, Expect=3e-28]; ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=114, Expect=1e-27]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=132, Expect=3e-34]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=91.3, Expect=4e-20]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=114, Expect=3e-28]} {RNA1509_46580} {RNA1310_33722} {RNA815_7677}
2. MligTC455_35773 89 1.86 Mlig455_064449, Mlig455_064456

Neo: -

Age: -

Region-enriched R2: 5.198/0.00725

NANP 4.567 0.800 - 0.986 0.886 0.939 0.956

Mlig455_064449 {REF} {Length: 503} {NoTransDecoderORF} {RNA1310_53432.2}

Mlig455_064456 {REF} {Length: 3122} {Pfam: Haloacid dehalogenase-like hydrolase [PF13419.8, score=56.3]; haloacid dehalogenase-like hydrolase [PF00702.28, score=55.3]; HAD-hyrolase-like [PF13242.8, score=44.6]} {Human: ENSG00000170191, NANP, N-acetylneuraminic acid phosphatase, [RH, Score=47.4, Expect=8e-06]} {Mouse: ENSMUSG00000053916, Nanp, N-acetylneuraminic acid phosphatase, [RH, Score=48.5, Expect=2e-06]} {Celegans: WBGene00018465, F45E1.4, [RH, Score=147, Expect=4e-43]} {Smed: dd_Smed_v6_2813_0_3, dd_Smed_v6_2813_0_3, [Score=174, Expect=2e-50]} {RNA1310_59243} {RNA815_62364}
3. MligTC455_38682 102 2.12 Mlig455_039641

Neo: -

Age: -

Region-enriched R2: 6.138/0.02363

SLC18A3 4.259 0.720 - 0.967 0.975 0.835 0.762 Mlig455_039641 {REF} {Length: 3925} {Pfam: Major Facilitator Superfamily [PF07690.18, score=147.1]; Sugar (and other) transporter [PF00083.26, score=29.0]; LacY proton/sugar symporter [PF01306.21, score=20.2]} {Human: ENSG00000187714, SLC18A3, solute carrier family 18 member A3, [RH, Score=469, Expect=9e-161]} {Mouse: ENSMUSG00000100241, Slc18a3, solute carrier family 18 (vesicular monoamine), member 3, [RH, Score=469, Expect=1e-160]} {Dmel: FBgn0270928, VAChT, Vesicular acetylcholine transporter, [RH, Score=513, Expect=2e-177]} {Celegans: WBGene00006756, unc-17, Vesicular acetylcholine transporter unc-17, [RH, Score=486, Expect=2e-167]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [RH, Score=563, Expect=0.0]} {RNA1310_28397} {RNA815_32284.1}
4. MligTC455_42376 61 1.27 Mlig455_069890

Neo: -

Age: -

4.17 0.708 - 0.943 0.957 0.762 0.800 Mlig455_069890 {REF} {Length: 630} {TRANSSPLICED} {Pfam: PAN domain [PF00024.28, score=26.1]} {RNA1509_53783} {RNA1310_37190} {RNA815_24434}
5. MligTC455_16749 454 9.45 Mlig455_001550, Mlig455_046548

Neo: -

Age: logFC(26M/2M)=0.515

Region-specific R2: 4.360

Region-enriched R2: 3.409/0.00015

TRAF4 4.018 0.753 - 0.954 0.883 0.701 0.727

Mlig455_001550 {REF} {Length: 4563} {Pfam: TRAF-type zinc finger [PF02176.20, score=81.2]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=27.3]; Seven in absentia protein family [PF03145.18, score=27.2]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=23.0]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=22.9]; zinc finger of C3HC4-type, RING [PF15227.8, score=20.4]; zf-RING of BARD1-type protein [PF14835.8, score=20.3]; Ring finger domain [PF13639.8, score=19.5]} {Human: ENSG00000076604, TRAF4, TNF receptor associated factor 4, [Score=237, Expect=4e-72]} {Mouse: ENSMUSG00000017386, Traf4, TNF receptor associated factor 4, [Score=241, Expect=7e-74]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=164, Expect=1e-44]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [RH, Score=276, Expect=1e-87]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [RH, Score=592, Expect=0.0]} {RNA1509_20900} {RNA1310_14813, RNA1509_20900} {RNA1509_20900, RNA815_2335.1}

Mlig455_046548 {REF} {Length: 3881} {Pfam: TRAF-type zinc finger [PF02176.20, score=81.2]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=27.3]; Seven in absentia protein family [PF03145.18, score=27.2]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=23.0]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=22.9]; zinc finger of C3HC4-type, RING [PF15227.8, score=20.4]; zf-RING of BARD1-type protein [PF14835.8, score=20.3]; Ring finger domain [PF13639.8, score=19.5]} {Human: ENSG00000076604, TRAF4, TNF receptor associated factor 4, [Score=236, Expect=1e-71]} {Mouse: ENSMUSG00000017386, Traf4, TNF receptor associated factor 4, [Score=240, Expect=3e-73]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=164, Expect=9e-45]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [RH, Score=275, Expect=6e-87]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [RH, Score=592, Expect=0.0]} {RNA1509_20900} {RNA1310_14813} {RNA815_2335.1}
6. MligTC455_37848 42 0.87 Mlig455_049400

Neo: -

Age: -

3.755 - - 0.987 0.979 0.801 0.988 Mlig455_049400 {REF} {Length: 2374} {RNA1509_58287} {RNA1310_1148.1} {RNA815_900}
7. MligTC455_40290 58 1.21 Mlig455_058728

Neo: -

Age: -

Region-enriched R2: 4.464/0.00807
Region-enriched R7: 3.833/0.03206

3.626 - - 0.984 0.951 0.841 0.850 Mlig455_058728 {REF} {Length: 1351} {Pfam: CUB domain [PF00431.22, score=48.4]} {RNA1310_48745} {RNA815_23305}
8. MligTC455_49307 122 2.55 Mlig455_055230

Neo: -

Age: -

Region-enriched R2: 4.447/0.04819

ZAN 3.6 0.833 - 0.920 0.984 0.863 - Mlig455_055230 {REF} {Length: 2947} {Pfam: Glycine rich protein [PF12810.9, score=28.6]} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=79.7, Expect=1e-14]} {Mouse: ENSMUSG00000079173, Zan, zonadhesin, [Score=80.1, Expect=7e-15]} {RNA1310_18897} {RNA815_40026}
9. MligTC455_40289 93 1.94 Mlig455_017727, Mlig455_056175

Neo: -

Age: -

BMP1, CUBN 3.573 - - 0.964 0.968 0.832 0.809

Mlig455_017727 {REF} {Length: 1202} {Pfam: CUB domain [PF00431.22, score=55.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=54.7, Expect=4e-08]; ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=52.0, Expect=3e-07]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=51.6, Expect=3e-07]; ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=49.7, Expect=1e-06]} {Dmel: FBgn0003719, tld, tolloid, [Score=51.2, Expect=3e-07]} {Smed: dd_Smed_v6_69474_0_1, dd_Smed_v6_69474_0_1, [Score=47.4, Expect=2e-07]} {RNA1310_48745} {RNA815_23305}

Mlig455_056175 {REF} {Length: 2747} {Pfam: CUB domain [PF00431.22, score=62.6]} {Human: ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=52.8, Expect=2e-07]; ENSG00000107611, CUBN, cubilin, [Score=51.6, Expect=4e-07]} {Mouse: ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=51.6, Expect=3e-07]; ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=49.7, Expect=1e-06]} {Dmel: FBgn0003719, tld, tolloid, [Score=51.2, Expect=3e-07]} {Smed: dd_Smed_v6_69474_0_1, dd_Smed_v6_69474_0_1, [Score=47.0, Expect=3e-07]} {RNA1310_48745} {RNA815_23305}
10. MligTC455_20443 430 8.96 Mlig455_010917, Mlig455_033173

Neo: -

Age: -

Region-specific R2: 4.126

Region-enriched R2: 3.438/0.00019

CFAP77 3.561 0.857 - 0.964 0.917 0.823 -

Mlig455_010917 {REF} {Length: 1338} {Pfam: Domain of unknown function (DUF4483) [PF14825.8, score=38.6]} {Human: ENSG00000188523, CFAP77, cilia and flagella associated protein 77, [Score=47.8, Expect=3e-06]} {Mouse: ENSMUSG00000079502, Cfap77, cilia and flagella associated protein 77, [Score=50.1, Expect=4e-07]} {Smed: dd_Smed_v6_5179_0_1, dd_Smed_v6_5179_0_1, [Score=84.3, Expect=4e-20]} {RNA1509_46220} {RNA1310_36457, RNA1509_46220} {RNA1509_46220, RNA815_17196}

Mlig455_033173 {REF} {Length: 978} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4483) [PF14825.8, score=19.5]} {RNA1509_46220} {RNA1310_36457} {RNA815_17196}
11. MligTC455_49491 136 2.83 Mlig455_054796

Neo: -

Age: -

Region-enriched R2: 7.065/0.00003

3.531 0.866 - 0.983 0.977 0.705 - Mlig455_054796 {REF} {Length: 1567} {RNA1509_22234} {RNA1310_23973} {RNA815_10832}
12. MligTC455_29915 50 1.04 Mlig455_027934

Neo: -

Age: Down-Up-Up

Region-enriched R2: 6.881/0.04464

ANGPTL1 3.513 0.749 - 0.957 0.904 0.903 - Mlig455_027934 {REF} {Length: 2265} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=43.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=48.9, Expect=9e-06]} {Dmel: FBgn0031804, CG9500, [Score=53.1, Expect=9e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=49.7, Expect=1e-06]} {RNA1509_53291} {RNA1310_38229.1} {RNA815_10579.1}
13. MligTC455_50860 144 3 Mlig455_040408

Neo: -

Age: -

Region-enriched R2: 3.612/0.00156

CPLX2 3.505 - - 0.836 0.952 0.806 0.911 Mlig455_040408 {REF} {Length: 3031} {Pfam: Synaphin protein [PF05835.14, score=107.3]} {Human: ENSG00000145920, CPLX2, complexin 2, [RH, Score=55.1, Expect=2e-10]} {Mouse: ENSMUSG00000025867, Cplx2, complexin 2, [RH, Score=50.8, Expect=2e-08]} {Dmel: FBgn0041605, cpx, complexin, [Score=72.0, Expect=1e-16]} {Celegans: WBGene00022271, cpx-1, Putative complexin-1, [Score=81.3, Expect=3e-20]} {Smed: dd_Smed_v6_9918_0_1, dd_Smed_v6_9918_0_1, [Score=84.7, Expect=8e-22]} {RNA1509_17814, RNA1509_20729} {RNA1310_16525, RNA1509_17814, RNA1509_20729} {RNA1509_17814, RNA1509_20729, RNA815_8066.1}
14. MligTC455_29914 44 0.91 Mlig455_027923

Neo: -

Age: Down-Up-Down

Region-enriched R2: 8.096/0.00455

ANGPTL3 3.493 0.747 - 0.962 0.831 0.953 - Mlig455_027923 {REF} {Length: 1663} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=70.5]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=60.5, Expect=9e-10]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=59.3, Expect=2e-09]; ENSG00000120332, TNN, tenascin N, [Score=58.9, Expect=3e-09]} {Mouse: ENSMUSG00000015829, Tnr, tenascin R, [Score=62.4, Expect=2e-10]} {Dmel: FBgn0031804, CG9500, [Score=76.3, Expect=6e-16]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=51.2, Expect=3e-07]} {RNA1509_53291} {RNA1310_58974} {RNA815_43288.3}
15. MligTC455_36842 340 7.08 Mlig455_056552

Neo: -

Age: -

Region-enriched R2: 2.409/0.00668

SYT11 3.481 0.727 - 0.957 0.904 0.893 - Mlig455_056552 {REF} {Length: 3533} {Pfam: C2 domain [PF00168.32, score=153.6]} {Human: ENSG00000132718, SYT11, synaptotagmin 11, [RH, Score=310, Expect=7e-102]} {Mouse: ENSMUSG00000068923, Syt11, synaptotagmin XI, [RH, Score=309, Expect=8e-102]} {Dmel: FBgn0028400, Syt4, Synaptotagmin 4, [RH, Score=355, Expect=3e-119]} {Celegans: WBGene00004924, snt-4, SyNapTotagmin, [RH, Score=237, Expect=1e-74]} {Smed: dd_Smed_v6_7243_0_1, dd_Smed_v6_7243_0_1, [Score=372, Expect=4e-127]} {RNA1509_16916, RNA1509_47189} {RNA1310_9964.1, RNA1509_16916, RNA1509_47189} {RNA1509_16916, RNA1509_47189, RNA815_17687}
16. MligTC455_33832 112 2.34 Mlig455_029411

Neo: -

Age: Up-Down-Down

Region-enriched R2: 5.300/0.00016
Region-enriched R8: 4.136/0.03070

GLRA3 3.476 0.711 - 0.905 0.974 0.886 - Mlig455_029411 {REF} {Length: 3686} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=149.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=84.5]} {Human: ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=257, Expect=5e-80]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=253, Expect=3e-78]; ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=250, Expect=4e-77]} {Mouse: ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=251, Expect=2e-77]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=249, Expect=5e-77]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=248, Expect=2e-76]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=243, Expect=1e-74]} {Dmel: FBgn0024963, GluClalpha, [Score=253, Expect=2e-78]} {Celegans: WBGene00000233, avr-15, GluClalpha2B protein, [Score=259, Expect=7e-81]} {Smed: dd_Smed_v6_11342_0_1, dd_Smed_v6_11342_0_1, [RH, Score=480, Expect=1e-167]} {RNA1509_35986} {RNA1310_35528} {RNA815_35433}
17. MligTC455_40352 49 1.03 Mlig455_024410

Neo: -

Age: -

3.475 0.832 - 0.881 0.969 - 0.793 Mlig455_024410 {REF} {Length: 1509} {TRANSSPLICED} {RNA1310_29008} {RNA815_41596}
18. MligTC455_34369 112 2.34 Mlig455_015308, Mlig455_015354, Mlig455_036248, Mlig455_068737, Mlig455_070110

Neo: -

Age: Up-Down-Up

Region-enriched R2: 5.462/0.00546

3.467 0.713 - 0.985 0.934 0.835 -

Mlig455_015308 {REF} {Length: 1459} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.9]} {RNA1310_34740} {RNA815_15663}

Mlig455_015354 {REF} {Length: 1446} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=66.3]; Sialidase, N-terminal domain [PF02973.18, score=18.5]} {RNA1310_34740} {RNA815_15663}

Mlig455_036248 {REF} {Length: 2111} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=120.9]; Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=28.5]; PAN domain [PF00024.28, score=19.9]} {RNA1509_45496} {RNA1310_2539.1} {RNA815_252.1}

Mlig455_068737 {REF} {Length: 1096} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=68.3]; Sialidase, N-terminal domain [PF02973.18, score=19.9]} {RNA1310_34740} {RNA815_37905}

Mlig455_070110 {REF} {Length: 1340} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=109.6]} {RNA1509_32599} {RNA1310_1659} {RNA815_252.1}
19. MligTC455_33704 135 2.81 Mlig455_002733

Neo: -

Age: Up-Down-Down

COL5A2 3.464 0.880 - 0.968 0.855 - 0.761 Mlig455_002733 {REF} {Length: 6615} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=136.4]; Myotubularin protein [PF12335.10, score=23.9]} {Human: ENSG00000204262, COL5A2, collagen type V alpha 2 chain, [Score=113, Expect=6e-25]; ENSG00000049089, COL9A2, collagen type IX alpha 2 chain, [Score=111, Expect=1e-24]} {Mouse: ENSMUSG00000026147, Col9a1, collagen, type IX, alpha 1, [Score=124, Expect=2e-28]; ENSMUSG00000026042, Col5a2, collagen, type V, alpha 2, [Score=122, Expect=1e-27]; ENSMUSG00000041984, Rptn, repetin, [Score=121, Expect=1e-27]; ENSMUSG00000045672, Col27a1, collagen, type XXVII, alpha 1, [Score=120, Expect=3e-27]} {Dmel: FBgn0016075, vkg, viking, [Score=106, Expect=5e-23]} {Celegans: WBGene00000708, col-135, COLlagen, [Score=84.0, Expect=2e-16]} {Smed: dd_Smed_v6_8075_0_1, dd_Smed_v6_8075_0_1, [Score=140, Expect=9e-34]} {RNA1310_28728} {RNA815_22052}
20. MligTC455_33039 312 6.51 Mlig455_032494

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.545/0.00267

PKDREJ 3.458 0.705 - 0.980 0.972 0.801 - Mlig455_032494 {REF} {Length: 11952} {Pfam: Polycystin cation channel [PF08016.14, score=289.9]; REJ domain [PF02010.17, score=90.4]; PLAT/LH2 domain [PF01477.25, score=68.4]; PKD domain [PF00801.22, score=57.9]; PKD domain [PF18911.2, score=36.7]; Ion transport protein [PF00520.33, score=36.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=30.0]; WSC domain [PF01822.21, score=23.3]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=267, Expect=1e-70]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=292, Expect=3e-78]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=136, Expect=2e-31]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=297, Expect=4e-80]} {Smed: dd_Smed_v6_15525_0_1, dd_Smed_v6_15525_0_1, [Score=1504, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
21. MligTC455_31933 105 2.18 Mlig455_062083

Neo: -

Age: -

ANGPTL1 3.452 0.708 - 0.925 0.954 0.865 - Mlig455_062083 {REF} {Length: 1024} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=156.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=135, Expect=7e-36]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=132, Expect=2e-34]; ENSG00000101280, ANGPT4, angiopoietin 4, [Score=132, Expect=9e-35]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=137, Expect=1e-36]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=132, Expect=4e-35]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=131, Expect=1e-34]} {Dmel: FBgn0034160, CG5550, [Score=130, Expect=2e-36]} {Celegans: WBGene00020516, T15B7.1, [Score=73.9, Expect=9e-15]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=126, Expect=2e-32]} {RNA1509_14033} {RNA1310_32107.2} {RNA815_17173.3}
22. MligTC455_27025 706 14.7 Mlig455_054786, Mlig455_054878

Neo: -

Age: -

Region-enriched R2: 3.519/0.00005

CD82 3.445 0.837 - 0.874 0.954 0.780 -

Mlig455_054786 {REF} {Length: 2796} {Pfam: Tetraspanin family [PF00335.22, score=142.8]} {Human: ENSG00000085117, CD82, CD82 molecule, [RH, Score=86.3, Expect=4e-19]} {Mouse: ENSMUSG00000027215, Cd82, CD82 antigen, [RH, Score=94.0, Expect=3e-22]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=98.6, Expect=6e-24]} {Celegans: WBGene00006632, tsp-6, Tetraspanin, [Score=74.7, Expect=1e-15]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [RH, Score=160, Expect=2e-47]} {RNA1509_20389, RNA1509_43644, RNA1509_56428} {RNA1310_8032.1, RNA1509_20389, RNA1509_43644, RNA1509_56428} {RNA1509_20389, RNA1509_43644, RNA1509_56428, RNA815_3380.1}

Mlig455_054878 {REF} {Length: 4398} {Pfam: Tetraspanin family [PF00335.22, score=143.7]} {Human: ENSG00000085117, CD82, CD82 molecule, [RH, Score=84.7, Expect=2e-18]} {Mouse: ENSMUSG00000027215, Cd82, CD82 antigen, [RH, Score=92.4, Expect=2e-21]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=99.8, Expect=4e-24]} {Celegans: WBGene00006643, tsp-17, TetraSPanin family, [RH, Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [RH, Score=160, Expect=2e-47]} {RNA1509_56428} {RNA1310_8032.2} {RNA815_3380.1}
23. MligTC455_39064 110 2.28 Mlig455_000222, Mlig455_058480

Neo: Irradiation

Age: -

Region-enriched R2: 5.418/0.00017

OSBPL1A 3.431 0.760 - 0.960 0.866 0.845 -

Mlig455_000222 {REF} {Length: 2113} {Pfam: Oxysterol-binding protein [PF01237.20, score=414.5]} {Human: ENSG00000141447, OSBPL1A, oxysterol binding protein like 1A, [RH, Score=375, Expect=2e-116]; ENSG00000130703, OSBPL2, oxysterol binding protein like 2, [RH, Score=357, Expect=8e-115]} {Mouse: ENSMUSG00000044252, Osbpl1a, oxysterol binding protein-like 1A, [RH, Score=378, Expect=4e-122]; ENSMUSG00000039050, Osbpl2, oxysterol binding protein-like 2, [RH, Score=367, Expect=6e-119]} {Dmel: FBgn0034951, CG3860, [RH, Score=409, Expect=1e-135]} {Celegans: WBGene00008832, obr-2, Oxysterol Binding protein (OSBP) Related, [RH, Score=239, Expect=3e-71]} {Smed: dd_Smed_v6_3179_0_1, dd_Smed_v6_3179_0_1, [RH, Score=385, Expect=3e-126]} {RNA1509_29630} {RNA1310_38654} {RNA815_7740}

Mlig455_058480 {REF} {Length: 2888} {TRANSSPLICED} {Pfam: Oxysterol-binding protein [PF01237.20, score=414.5]} {Human: ENSG00000141447, OSBPL1A, oxysterol binding protein like 1A, [RH, Score=375, Expect=2e-116]; ENSG00000130703, OSBPL2, oxysterol binding protein like 2, [RH, Score=357, Expect=8e-115]} {Mouse: ENSMUSG00000044252, Osbpl1a, oxysterol binding protein-like 1A, [RH, Score=378, Expect=4e-122]; ENSMUSG00000039050, Osbpl2, oxysterol binding protein-like 2, [RH, Score=367, Expect=6e-119]} {Dmel: FBgn0034951, CG3860, [RH, Score=409, Expect=1e-135]} {Celegans: WBGene00008832, obr-2, Oxysterol Binding protein (OSBP) Related, [RH, Score=239, Expect=3e-71]} {Smed: dd_Smed_v6_3179_0_1, dd_Smed_v6_3179_0_1, [RH, Score=385, Expect=3e-126]} {RNA1509_29630} {RNA1310_38654} {RNA815_26411}
24. MligTC455_18106 1217 25.35 Mlig455_066402

Neo: -

Age: -

C7orf31 3.413 0.810 - 0.754 0.892 0.957 - Mlig455_066402 {REF} {Length: 3205} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4555) [PF15093.8, score=102.0]} {Human: ENSG00000153790, C7orf31, chromosome 7 open reading frame 31, [RH, Score=119, Expect=3e-27]} {Mouse: ENSMUSG00000029828, 4921507P07Rik, RIKEN cDNA 4921507P07 gene, [RH, Score=110, Expect=1e-24]} {RNA1509_11592} {RNA1310_4450} {RNA815_12248}
25. MligTC455_29157 30 0.63 Mlig455_018723

Neo: -

Age: -

3.412 - - 0.979 0.735 0.761 0.937 Mlig455_018723 {REF} {Length: 504} {RNA1509_38365} {RNA1310_117516} {RNA815_19813}
26. MligTC455_17947 64 1.34 Mlig455_042563

Neo: -

Age: -

Region-enriched R2: 7.054/0.00113

ASCL5 3.403 0.754 - 0.970 0.861 0.818 - Mlig455_042563 {REF} {Length: 1821} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=52.5]} {Human: ENSG00000232237, ASCL5, achaete-scute family bHLH transcription factor 5, [Score=84.7, Expect=6e-20]} {Mouse: ENSMUSG00000097918, Ascl5, achaete-scute family bHLH transcription factor 5, [Score=84.0, Expect=5e-20]} {Dmel: FBgn0002922, nau, nautilus, [Score=49.3, Expect=6e-07]} {Celegans: WBGene00001952, hlh-6, Helix-loop-helix protein 6, [RH, Score=90.9, Expect=4e-22]} {Smed: dd_Smed_v6_14753_0_1, dd_Smed_v6_14753_0_1, [RH, Score=76.6, Expect=2e-17]} {RNA1310_71187}
27. MligTC455_44922 15 0.31 Mlig455_040611

Neo: -

Age: -

AC254952.1 3.401 0.756 - 0.983 0.870 0.792 - Mlig455_040611 {REF} {Length: 1658} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=86.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=85.3]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=1e-40]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=2e-40]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=2e-40]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=147, Expect=9e-39]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=129, Expect=1e-32]} {Celegans: WBGene00001133, eat-2, Neuronal acetylcholine receptor subunit eat-2, [Score=136, Expect=2e-35]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=136, Expect=2e-35]} {RNA1310_45581} {RNA815_21574}
28. MligTC455_29152 33 0.68 Mlig455_018706

Neo: -

Age: -

3.389 - - 0.975 0.735 0.742 0.937 Mlig455_018706 {REF} {Length: 1786} {RNA1509_38365} {RNA1310_54025} {RNA815_28950}
29. MligTC455_39988 83 1.73 Mlig455_062081

Neo: -

Age: -

3.374 0.708 - 0.976 0.969 0.721 - Mlig455_062081 {REF} {Length: 447} {NoTransDecoderORF} {RNA1509_50426} {RNA1310_88257} {RNA815_17173.4}
30. MligTC455_47080 362 7.54 Mlig455_037356

Neo: -

Age: -

Region-enriched R2: 2.691/0.00566

SSUH2 3.372 0.789 - 0.728 0.959 0.896 - Mlig455_037356 {REF} {Length: 1984} {Pfam: DnaJ central domain [PF00684.21, score=20.9]} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=189, Expect=3e-56]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=156, Expect=5e-44]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=90.9, Expect=7e-20]} {RNA1509_29510} {RNA1310_15488, RNA1509_29510} {RNA1509_29510, RNA815_5650}
31. MligTC455_15766 769 16.03 Mlig455_020838, Mlig455_020943

Neo: -

Age: -

Region-enriched R2: 1.912/0.04321

3.371 0.757 - 0.782 0.957 0.875 -

Mlig455_020838 {REF} {Length: 1388} {RNA1310_25770.1} {RNA815_11095}

Mlig455_020943 {REF} {Length: 1423} {RNA1310_25770.1} {RNA815_11095}
32. MligTC455_19277 1013 21.11 Mlig455_059600

Neo: -

Age: -

Region-specific R2: 4.883

Region-enriched R2: 5.766/0.00000
Region-enriched R3: 2.030/0.00976

3.37 0.704 - 0.953 0.871 0.842 - Mlig455_059600 {REF} {Length: 827} {NoTransDecoderORF} {RNA1509_43907} {RNA1310_81348}
33. MligTC455_50844 224 4.67 Mlig455_018511

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.591/0.00005

SSUH2 3.359 0.732 - 0.961 0.814 0.852 - Mlig455_018511 {REF} {Length: 1843} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=120, Expect=2e-29]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=95.5, Expect=3e-21]} {RNA1509_39980} {RNA1310_60742, RNA1509_39980} {RNA1509_39980, RNA815_28938}
34. MligTC455_26652 30 0.63 Mlig455_036452

Neo: -

Age: -

NR2E1 3.355 0.735 - 0.941 0.968 0.711 - Mlig455_036452 {REF} {Length: 2848} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=99.9]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=55.3]} {Human: ENSG00000112333, NR2E1, nuclear receptor subfamily 2 group E member 1, [Score=139, Expect=2e-35]} {Mouse: ENSMUSG00000019803, Nr2e1, nuclear receptor subfamily 2, group E, member 1, [Score=139, Expect=1e-35]} {Dmel: FBgn0015381, dsf, dissatisfaction, [Score=129, Expect=6e-31]} {Celegans: WBGene00021417, nhr-236, Nuclear Hormone Receptor family, [RH, Score=135, Expect=1e-35]} {Smed: dd_Smed_v6_25420_0_1, dd_Smed_v6_25420_0_1, [RH, Score=182, Expect=3e-50]} {RNA1310_57853} {RNA815_57699}
35. MligTC455_45801 473 9.86 Mlig455_060953

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.971/0.00047

TENM1 3.344 0.950 - 0.736 0.738 0.920 - Mlig455_060953 {REF} {Length: 10667} {Pfam: EGF-like domain [PF07974.15, score=60.5]} {Human: ENSG00000009694, TENM1, teneurin transmembrane protein 1, [RH, Score=739, Expect=0.0]} {Mouse: ENSMUSG00000016150, Tenm1, teneurin transmembrane protein 1, [RH, Score=750, Expect=0.0]} {Dmel: FBgn0004449, Ten-m, Tenascin major, [Score=710, Expect=0.0]} {Celegans: WBGene00006498, ten-1, Teneurin-1, [RH, Score=459, Expect=6e-130]} {Smed: dd_Smed_v6_5439_0_3, dd_Smed_v6_5439_0_3, [Score=593, Expect=5e-175]} {RNA1509_19240} {RNA1310_136, RNA1509_19240} {RNA1509_19240, RNA815_6451}
36. MligTC455_30463 95 1.98 Mlig455_000250, Mlig455_058521, Mlig455_058532

Neo: -

Age: -

3.336 0.871 - 0.971 0.763 0.731 -

Mlig455_000250 {REF} {Length: 1994} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=19.7]} {RNA1310_59451} {RNA815_40085}

Mlig455_058521 {REF} {Length: 1237} {RNA1310_56656} {RNA815_40085}

Mlig455_058532 {REF} {Length: 1973} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=19.5]} {RNA1310_59451} {RNA815_40085}
37. MligTC455_41368 369 7.68 Mlig455_007683, Mlig455_020872, Mlig455_020918, Mlig455_020998

Neo: -

Age: -

3.33 0.829 - 0.779 0.971 0.751 -

Mlig455_007683 {REF} {Length: 1379} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020872 {REF} {Length: 1217} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020918 {REF} {Length: 1220} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020998 {REF} {Length: 1235} {RNA1310_25040.1} {RNA815_12562.1}
38. MligTC455_52393 60 1.25 Mlig455_039640

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.560

Region-enriched R2: 5.399/0.01138

CHAT 3.329 0.718 - 0.954 0.781 - 0.876 Mlig455_039640 {REF} {Length: 3681} {TRANSSPLICED} {Pfam: Choline/Carnitine o-acyltransferase [PF00755.22, score=546.9]} {Human: ENSG00000070748, CHAT, choline O-acetyltransferase, [RH, Score=520, Expect=1e-176]} {Mouse: ENSMUSG00000021919, Chat, choline acetyltransferase, [RH, Score=521, Expect=3e-177]} {Dmel: FBgn0000303, ChAT, Choline acetyltransferase, [Score=452, Expect=1e-149]} {Celegans: WBGene00000481, cha-1, Choline O-acetyltransferase, [RH, Score=356, Expect=1e-113]} {Smed: dd_Smed_v6_6208_0_1, dd_Smed_v6_6208_0_1, [Score=535, Expect=0.0]} {RNA1509_40088} {RNA1310_20833} {RNA815_26395}
39. MligTC455_42256 163 3.39 Mlig455_054046

Neo: -

Age: Down-Up-Up

LDB2 3.284 0.770 - 0.962 - 0.782 0.770 Mlig455_054046 {REF} {Length: 2089} {Pfam: LIM-domain binding protein [PF01803.18, score=164.3]; LIM interaction domain (LID) [PF17916.3, score=55.5]} {Human: ENSG00000169744, LDB2, LIM domain binding 2, [RH, Score=390, Expect=4e-132]} {Mouse: ENSMUSG00000039706, Ldb2, LIM domain binding 2, [RH, Score=388, Expect=3e-131]} {Dmel: FBgn0013764, Chi, Chip, [RH, Score=332, Expect=9e-107]} {Celegans: WBGene00002261, ldb-1, F58A3.1a; LIM Domain Binding protein, [RH, Score=155, Expect=2e-40]} {Smed: dd_Smed_v6_3678_0_1, dd_Smed_v6_3678_0_1, [Score=321, Expect=1e-102]} {RNA1310_27326} {RNA815_22302}
40. MligTC455_49620 290 6.04 Mlig455_001138, Mlig455_001300

Neo: -

Age: -

Region-enriched R2: 5.198/0.00000

ELAVL3, ELAVL4 3.264 0.769 - 0.730 0.809 0.956 -

Mlig455_001138 {REF} {Length: 3131} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=206.7]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=37.5]; Occluded RNA-recognition motif [PF16842.7, score=27.0]} {Human: ENSG00000162374, ELAVL4, ELAV like RNA binding protein 4, [Score=268, Expect=6e-85]; ENSG00000196361, ELAVL3, ELAV like RNA binding protein 3, [Score=268, Expect=3e-85]; ENSG00000107105, ELAVL2, ELAV like RNA binding protein 2, [Score=268, Expect=2e-84]} {Mouse: ENSMUSG00000003410, Elavl3, ELAV like RNA binding protein 3, [RH, Score=270, Expect=2e-87]} {Dmel: FBgn0010263, Rbp9, RNA-binding protein 9, [Score=273, Expect=2e-86]} {Celegans: WBGene00001368, exc-7, [RH, Score=327, Expect=6e-107]} {Smed: dd_Smed_v6_13151_0_1, dd_Smed_v6_13151_0_1, [RH, Score=269, Expect=8e-84]} {RNA1509_28072} {RNA1310_22289} {RNA815_15133}

Mlig455_001300 {REF} {Length: 3150} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=203.6]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=36.4]; Occluded RNA-recognition motif [PF16842.7, score=27.0]} {Human: ENSG00000196361, ELAVL3, ELAV like RNA binding protein 3, [Score=274, Expect=4e-87]; ENSG00000162374, ELAVL4, ELAV like RNA binding protein 4, [Score=271, Expect=6e-86]; ENSG00000107105, ELAVL2, ELAV like RNA binding protein 2, [Score=268, Expect=3e-85]; ENSG00000066044, ELAVL1, ELAV like RNA binding protein 1, [Score=262, Expect=3e-83]} {Mouse: ENSMUSG00000003410, Elavl3, ELAV like RNA binding protein 3, [RH, Score=271, Expect=7e-88]} {Dmel: FBgn0010263, Rbp9, RNA-binding protein 9, [Score=270, Expect=4e-85]} {Celegans: WBGene00001368, exc-7, [RH, Score=326, Expect=1e-106]} {Smed: dd_Smed_v6_11311_0_2, dd_Smed_v6_11311_0_2, [RH, Score=300, Expect=2e-97]} {RNA1509_28072} {RNA1310_22289} {RNA815_15133}
41. MligTC455_46430 62 1.29 Mlig455_057117, Mlig455_069301

Neo: -

Age: -

GUCY2F 3.248 0.754 - 0.967 0.746 0.781 -

Mlig455_057117 {REF} {Length: 2651} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=196.0]; Nitrate and nitrite sensing [PF08376.12, score=82.5]; Heme NO binding associated [PF07701.16, score=28.2]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=247, Expect=9e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=242, Expect=3e-68]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=238, Expect=5e-67]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=246, Expect=7e-70]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=242, Expect=2e-68]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=241, Expect=7e-68]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=239, Expect=3e-67]} {Dmel: FBgn0053958, CG33958, [Score=266, Expect=4e-79]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=235, Expect=3e-66]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=238, Expect=4e-67]} {RNA1509_38781} {RNA1310_35456} {RNA815_22108}

Mlig455_069301 {REF} {Length: 2370} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=178.1]; Nitrate and nitrite sensing [PF08376.12, score=82.3]; Heme NO binding associated [PF07701.16, score=28.0]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=232, Expect=2e-64]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=232, Expect=1e-64]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=225, Expect=5e-62]} {Dmel: FBgn0053958, CG33958, [Score=250, Expect=5e-73]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=223, Expect=1e-61]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=221, Expect=4e-61]} {RNA1509_38781} {RNA1310_35456} {RNA815_24181}
42. MligTC455_37010 127 2.64 Mlig455_012355

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.232/0.00085

3.241 0.813 - 0.956 0.769 - 0.703 Mlig455_012355 {REF} {Length: 7737} {Pfam: HGWP repeat [PF03578.17, score=19.0]} {RNA1509_28298} {RNA1310_3268} {RNA815_628}
43. MligTC455_19912 180 3.75 Mlig455_035062, Mlig455_035081

Neo: -

Age: -

Region-enriched R2: 3.574/0.00043

Regeneration-upregulated R6: 3.449

Regeneration-enriched R6: 3.449

SOX2 3.214 0.802 0.701 0.966 0.745 - -

Mlig455_035062 {REF} {Length: 2855} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.6]; HMG-box domain [PF09011.12, score=43.3]; SOX transcription factor [PF12336.10, score=31.1]} {Human: ENSG00000181449, SOX2, SRY-box 2, [Score=182, Expect=7e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=182, Expect=3e-53]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=168, Expect=6e-45]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=174, Expect=1e-50]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=161, Expect=2e-43]} {RNA1509_11450} {RNA1310_17800.1} {RNA815_36848}

Mlig455_035081 {REF} {Length: 2804} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.8]; HMG-box domain [PF09011.12, score=41.9]; SOX transcription factor [PF12336.10, score=30.8]} {Human: ENSG00000181449, SOX2, SRY-box 2, [Score=182, Expect=5e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=183, Expect=3e-53]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=171, Expect=1e-45]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=174, Expect=9e-51]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=161, Expect=2e-43]} {RNA1509_11450} {RNA1310_17800.1} {RNA815_36848}
44. MligTC455_34524 155 3.22 Mlig455_021291

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.905

Region-enriched R2: 4.200/0.01842

3.21 - - 0.967 0.761 0.780 0.702 Mlig455_021291 {REF} {Length: 1478} {NoTransDecoderORF} {RNA1509_56543} {RNA1310_26920, RNA1509_56543} {RNA1509_56543, RNA815_11718}
45. MligTC455_49877 188 3.91 Mlig455_027465

Neo: -

Age: -

Region-enriched R2: 3.005/0.04141

AC254952.1 3.198 - - 0.727 0.990 0.768 0.713 Mlig455_027465 {REF} {Length: 2059} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=89.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=80.0]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=6e-38]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=144, Expect=9e-38]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=141, Expect=2e-36]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=141, Expect=1e-36]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=141, Expect=6e-37]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=139, Expect=5e-36]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=134, Expect=2e-34]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=132, Expect=4e-33]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=126, Expect=6e-32]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=131, Expect=2e-33]} {RNA1310_26175} {RNA815_7952}
46. MligTC455_18607 203 4.23 Mlig455_012344, Mlig455_012722

Neo: -

Age: -

Region-enriched R2: 3.338/0.02204

ANKRD63 3.144 - - 0.950 0.754 0.734 0.706

Mlig455_012344 {REF} {Length: 1989} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=77.3]; Ankyrin repeats (many copies) [PF13637.8, score=67.3]; Ankyrin repeat [PF00023.32, score=56.6]; Ankyrin repeats (many copies) [PF13857.8, score=50.3]; Ankyrin repeat [PF13606.8, score=47.6]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=55.5, Expect=5e-08]} {Celegans: WBGene00006882, vab-19, VAB-19, [Score=52.0, Expect=5e-07]} {Smed: dd_Smed_v6_11187_0_1, dd_Smed_v6_11187_0_1, [Score=59.3, Expect=2e-09]} {RNA1310_37830} {RNA815_38436}

Mlig455_012722 {REF} {Length: 2256} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=77.2]; Ankyrin repeats (many copies) [PF13637.8, score=67.3]; Ankyrin repeat [PF00023.32, score=56.6]; Ankyrin repeats (many copies) [PF13857.8, score=50.3]; Ankyrin repeat [PF13606.8, score=47.6]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Dmel: FBgn0031473, CG3104, [Score=54.7, Expect=5e-08]} {Celegans: WBGene00006882, vab-19, VAB-19, [Score=52.0, Expect=5e-07]} {Smed: dd_Smed_v6_11187_0_2, dd_Smed_v6_11187_0_2, [Score=59.7, Expect=1e-09]} {RNA1310_37830} {RNA815_38436}
47. MligTC455_24162 48 1 Mlig455_014024

Neo: -

Age: -

3.131 0.708 - 0.987 0.700 0.736 - Mlig455_014024 {REF} {Length: 3118} {RNA1310_27501} {RNA815_14263}
48. MligTC455_23567 109 2.27 Mlig455_013185

Neo: -

Age: Down-Up-Down

BCHE 2.833 - - 0.954 0.962 - 0.917 Mlig455_013185 {REF} {Length: 4455} {Pfam: Carboxylesterase family [PF00135.30, score=432.1]; alpha/beta hydrolase fold [PF07859.15, score=35.5]} {Human: ENSG00000114200, BCHE, butyrylcholinesterase, [Score=317, Expect=9e-99]; ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=312, Expect=2e-96]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [Score=324, Expect=3e-101]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=249, Expect=8e-73]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=327, Expect=2e-102]} {Smed: dd_Smed_v6_15930_0_1, dd_Smed_v6_15930_0_1, [RH, Score=412, Expect=4e-134]} {RNA1509_26775} {RNA1310_8383.1} {RNA815_10983}
49. MligTC455_48022 1337 27.86 Mlig455_045267, Mlig455_069186

Neo: -

Age: -

Region-enriched R2: 2.130/0.00146

2.829 - - 0.990 0.987 0.852 -

Mlig455_045267 {REF} {Length: 3628} {Pfam: Ankyrin repeats (many copies) [PF13857.8, score=29.5]; Ankyrin repeats (many copies) [PF13637.8, score=28.4]; Ankyrin repeats (3 copies) [PF12796.9, score=28.3]; Ankyrin repeat [PF13606.8, score=23.5]} {Celegans: WBGene00009375, F34D10.6, [Score=57.0, Expect=6e-08]} {Smed: dd_Smed_v6_5594_0_3, dd_Smed_v6_5594_0_3, [Score=58.5, Expect=1e-08]} {RNA1509_17412, RNA1509_32079} {RNA1310_5952, RNA1509_17412, RNA1509_32079} {RNA1509_17412, RNA1509_32079, RNA815_2323}

Mlig455_069186 {REF} {Length: 3598} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=30.4]; Ankyrin repeats (3 copies) [PF12796.9, score=30.1]; Ankyrin repeats (many copies) [PF13857.8, score=29.5]; Ankyrin repeat [PF13606.8, score=24.1]} {Celegans: WBGene00009375, F34D10.6, [Score=56.6, Expect=6e-08]} {Smed: dd_Smed_v6_5594_0_4, dd_Smed_v6_5594_0_4, [Score=59.3, Expect=7e-09]} {RNA1509_52963} {RNA1310_5952, RNA1509_52963} {RNA1509_52963, RNA815_2323}
50. MligTC455_34614 24 0.5 Mlig455_060978

Neo: -

Age: -

2.802 - - 0.976 0.898 0.928 - Mlig455_060978 {REF} {Length: 1770} {RNA1310_81929}
51. MligTC455_19040 49 1.03 Mlig455_003437

Neo: -

Age: -

Region-enriched R2: 6.133/0.00615
Region-enriched R3: 4.021/0.03085

CAV1 2.801 - - 0.883 0.968 0.950 - Mlig455_003437 {REF} {Length: 808} {Pfam: Caveolin [PF01146.19, score=118.3]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=101, Expect=7e-28]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=102, Expect=2e-28]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=73.6, Expect=9e-17]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=142, Expect=8e-45]} {RNA1509_53381} {RNA1310_97043} {RNA815_32565}
52. MligTC455_46831 32 0.66 Mlig455_000140

Neo: -

Age: -

2.789 - - 0.972 0.922 - 0.895 Mlig455_000140 {REF} {Length: 1100}
53. MligTC455_13974 47 0.99 Mlig455_057616

Neo: -

Age: Up-Down-Up

Region-enriched R2: 6.685/0.01506

OTOP2 2.782 - - 0.909 0.923 0.950 - Mlig455_057616 {REF} {Length: 8915} {Pfam: Otopetrin [PF03189.15, score=235.3]} {Human: ENSG00000183034, OTOP2, otopetrin 2, [Score=56.2, Expect=1e-07]} {Mouse: ENSMUSG00000050201, Otop2, otopetrin 2, [Score=60.5, Expect=4e-09]} {Dmel: FBgn0259150, CG42265, [Score=196, Expect=3e-52]} {Celegans: WBGene00010403, otpl-8, OToPetrin-Like, [Score=114, Expect=3e-26]} {Smed: dd_Smed_v6_13612_0_4, dd_Smed_v6_13612_0_4, [Score=295, Expect=4e-91]} {RNA1509_7353} {RNA1310_933} {RNA815_252.1}
54. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

2.773 - - 0.986 0.924 0.863 - Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
55. MligTC455_51536 78 1.62 Mlig455_040699

Neo: -

Age: -

2.766 - - 0.954 0.889 0.923 - Mlig455_040699 {REF} {Length: 2015} {RNA1310_34295.1} {RNA815_22630}
56. MligTC455_50567 146 3.04 Mlig455_012858

Neo: -

Age: -

Region-specific R2: 6.162

Region-enriched R2: 5.988/0.01054

2.754 - - 0.920 0.971 0.863 - Mlig455_012858 {REF} {Length: 1282} {Pfam: F5/8 type C domain [PF00754.27, score=27.5]} {Smed: dd_Smed_v6_36585_0_1, dd_Smed_v6_36585_0_1, [RH, Score=64.3, Expect=4e-12]} {RNA1310_34633} {RNA815_12537}
57. MligTC455_17646 1198 24.96 Mlig455_048620, Mlig455_048699, Mlig455_048734

Neo: -

Age: logFC(26M/2M)=0.248

Region-enriched R2: 1.637/0.02593
Region-enriched R5: 1.108/0.02454

WDR86 2.752 - - 0.939 0.977 0.836 -

Mlig455_048620 {REF} {Length: 3284} {Pfam: WD domain, G-beta repeat [PF00400.34, score=149.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.9]; PQQ-like domain [PF13570.8, score=25.8]; Nucleoporin Nup120/160 [PF11715.10, score=22.0]} {Human: ENSG00000187260, WDR86, WD repeat domain 86, [RH, Score=318, Expect=6e-105]} {Mouse: ENSMUSG00000055235, Wdr86, WD repeat domain 86, [RH, Score=313, Expect=2e-103]} {Dmel: FBgn0283468, slmb, supernumerary limbs, [Score=125, Expect=2e-30]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [Score=135, Expect=2e-34]} {Smed: dd_Smed_v6_19827_0_1, dd_Smed_v6_19827_0_1, [RH, Score=425, Expect=5e-147]} {RNA1509_20850} {RNA1310_16023.1, RNA1509_20850} {RNA1509_20850, RNA815_7261}

Mlig455_048699 {REF} {Length: 2794} {Pfam: WD domain, G-beta repeat [PF00400.34, score=149.1]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.7]; PQQ-like domain [PF13570.8, score=25.5]; Nucleoporin Nup120/160 [PF11715.10, score=22.0]} {Human: ENSG00000187260, WDR86, WD repeat domain 86, [RH, Score=318, Expect=6e-105]} {Mouse: ENSMUSG00000055235, Wdr86, WD repeat domain 86, [RH, Score=314, Expect=2e-103]} {Dmel: FBgn0283468, slmb, supernumerary limbs, [Score=124, Expect=2e-30]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [Score=136, Expect=2e-34]} {Smed: dd_Smed_v6_19827_0_1, dd_Smed_v6_19827_0_1, [RH, Score=423, Expect=4e-146]} {RNA1509_20850} {RNA1310_16023.2} {RNA815_7261}

Mlig455_048734 {REF} {Length: 3308} {Pfam: WD domain, G-beta repeat [PF00400.34, score=149.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.9]; PQQ-like domain [PF13570.8, score=25.8]; Nucleoporin Nup120/160 [PF11715.10, score=22.0]} {Human: ENSG00000187260, WDR86, WD repeat domain 86, [RH, Score=318, Expect=6e-105]} {Mouse: ENSMUSG00000055235, Wdr86, WD repeat domain 86, [RH, Score=313, Expect=2e-103]} {Dmel: FBgn0283468, slmb, supernumerary limbs, [Score=125, Expect=2e-30]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [Score=135, Expect=2e-34]} {Smed: dd_Smed_v6_19827_0_1, dd_Smed_v6_19827_0_1, [RH, Score=425, Expect=5e-147]} {RNA1509_20850} {RNA1310_16023.1} {RNA815_7261}
58. MligTC455_38368 107 2.24 Mlig455_026435, Mlig455_044757

Neo: -

Age: Up-Down-Down

SSUH2 2.743 - - 0.958 0.925 0.860 -

Mlig455_026435 {REF} {Length: 1789} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [RH, Score=233, Expect=1e-72]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [RH, Score=195, Expect=1e-58]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=117, Expect=3e-29]} {RNA1509_6425} {RNA1310_32434} {RNA815_16161}

Mlig455_044757 {REF} {Length: 883} {TRANSSPLICED} {RNA1509_28356} {RNA1310_61125} {RNA815_53103}
59. MligTC455_47094 240 5.01 Mlig455_014204

Neo: -

Age: logFC(26M/2M)=-0.357

2.743 - - 0.912 0.971 0.860 - Mlig455_014204 {REF} {Length: 3346} {Smed: dd_Smed_v6_4351_0_1, dd_Smed_v6_4351_0_1, [RH, Score=238, Expect=1e-74]} {RNA1509_35661} {RNA1310_8437, RNA1509_35661} {RNA1509_35661, RNA815_15552}
60. MligTC455_17701 1279 26.65 Mlig455_051483

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.592

Region-enriched R2: 6.602/0.00000
Region-enriched R3: 2.598/0.04295

2.738 - - 0.921 0.952 0.865 - Mlig455_051483 {REF} {Length: 1833} {RNA1509_14131} {RNA1310_69964.2, RNA1509_14131} {RNA1509_14131, RNA815_35453.1}
61. MligTC455_19266 1038 21.61 Mlig455_004528, Mlig455_028530

Neo: -

Age: -

Region-specific R2: 2.706

Region-enriched R2: 1.766/0.00005

NCALD 2.734 - - 0.922 0.976 0.836 -

Mlig455_004528 {REF} {Length: 3958} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_14564} {RNA1310_18405, RNA1509_14564} {RNA1509_14564, RNA815_10180.1}

Mlig455_028530 {REF} {Length: 3453} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_13995, RNA1509_14564, RNA1509_30926} {RNA1310_18405, RNA1509_13995, RNA1509_30926} {RNA1509_13995, RNA1509_30926, RNA815_10180.1}
62. MligTC455_35258 2779 57.89 Mlig455_040964

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.469

Region-enriched R2: 1.501/0.00133

2.731 - - 0.956 0.956 0.819 - Mlig455_040964 {REF} {Length: 8259} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=543, Expect=9e-160]} {RNA1509_16633, RNA1509_52679} {RNA1310_236.2, RNA1509_16633} {RNA1509_16633, RNA815_77.1}
63. MligTC455_16248 132 2.74 Mlig455_038325, Mlig455_050222, Mlig455_050231

Neo: -

Age: -

CHRNA3 2.729 - - 0.952 0.841 0.936 -

Mlig455_038325 {REF} {Length: 1078} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=200.0]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=192, Expect=4e-57]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=194, Expect=7e-58]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=190, Expect=1e-56]} {Dmel: FBgn0004118, nAChRbeta2, nicotinic Acetylcholine Receptor beta2, [Score=206, Expect=1e-62]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=186, Expect=4e-55]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=216, Expect=5e-67]} {RNA1310_44575} {RNA815_22042}

Mlig455_050222 {REF} {Length: 2164} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=202.4]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=197.9]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=348, Expect=5e-114]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=335, Expect=4e-109]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=348, Expect=2e-114]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=343, Expect=2e-112]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=335, Expect=5e-109]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=397, Expect=1e-133]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=338, Expect=2e-110]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=489, Expect=5e-170]} {RNA1310_44575} {RNA815_22042}

Mlig455_050231 {REF} {Length: 2219} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=203.3]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=143.9]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=304, Expect=5e-99]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=299, Expect=8e-97]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=293, Expect=2e-94]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=290, Expect=7e-92]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=302, Expect=3e-98]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=296, Expect=3e-96]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=291, Expect=5e-94]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=352, Expect=8e-117]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=303, Expect=5e-99]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=424, Expect=2e-146]} {RNA1310_44575} {RNA815_22042}
64. MligTC455_21019 17 0.35 Mlig455_007175

Neo: -

Age: -

ZIC3 2.724 - - 0.951 0.927 0.846 - Mlig455_007175 {REF} {Length: 2278} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=58.4]; Zic proteins zinc finger domain [PF18366.3, score=50.3]; Zinc-finger double domain [PF13465.8, score=47.7]} {Human: ENSG00000156925, ZIC3, Zic family member 3, [RH, Score=275, Expect=2e-86]; ENSG00000152977, ZIC1, Zic family member 1, [RH, Score=273, Expect=6e-86]; ENSG00000043355, ZIC2, Zic family member 2, [RH, Score=271, Expect=2e-84]; ENSG00000139800, ZIC5, Zic family member 5, [RH, Score=268, Expect=6e-82]; ENSG00000174963, ZIC4, Zic family member 4, [RH, Score=266, Expect=2e-84]} {Mouse: ENSMUSG00000067860, Zic3, zinc finger protein of the cerebellum 3, [RH, Score=276, Expect=4e-87]; ENSMUSG00000032368, Zic1, zinc finger protein of the cerebellum 1, [RH, Score=273, Expect=3e-86]; ENSMUSG00000041703, Zic5, zinc finger protein of the cerebellum 5, [RH, Score=271, Expect=2e-83]} {Dmel: FBgn0003002, opa, odd paired, [Score=268, Expect=9e-83]} {Celegans: WBGene00004335, ref-2, REgulator of Fusion, [RH, Score=199, Expect=1e-59]} {Smed: dd_Smed_v6_15531_0_1, dd_Smed_v6_15531_0_1, [RH, Score=287, Expect=1e-91]} {RNA1509_20828} {RNA1310_79736} {RNA815_54343}
65. MligTC455_23150 3195 66.56 Mlig455_009524, Mlig455_009530

Neo: -

Age: -

Region-enriched R2: 3.504/0.00000
Region-enriched R3: 1.656/0.02560

CDK16 2.723 - - 0.836 0.958 0.929 -

Mlig455_009524 {REF} {Length: 3287} {Pfam: Protein kinase domain [PF00069.27, score=218.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.2]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [RH, Score=463, Expect=7e-159]; ENSG00000059758, CDK17, cyclin dependent kinase 17, [RH, Score=447, Expect=2e-151]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [RH, Score=464, Expect=2e-158]; ENSMUSG00000020015, Cdk17, cyclin-dependent kinase 17, [RH, Score=449, Expect=2e-152]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=362, Expect=2e-118]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [RH, Score=417, Expect=3e-138]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [RH, Score=449, Expect=6e-151]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}

Mlig455_009530 {REF} {Length: 3384} {Pfam: Protein kinase domain [PF00069.27, score=208.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [Score=432, Expect=5e-147]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [Score=431, Expect=4e-146]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=329, Expect=9e-107]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [Score=392, Expect=2e-130]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [Score=411, Expect=6e-137]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}
66. MligTC455_46188 25 0.51 Mlig455_039664, Mlig455_039727

Neo: -

Age: -

2.723 - - 0.972 0.931 0.820 -

Mlig455_039664 {REF} {Length: 1353}

Mlig455_039727 {REF} {Length: 1348}
67. MligTC455_19079 218 4.54 Mlig455_008746, Mlig455_008760

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.705

Region-enriched R2: 6.864/0.00152

2.722 - - 0.967 0.835 0.920 -

Mlig455_008746 {REF} {Length: 652} {RNA1310_75395.1} {RNA815_42524}

Mlig455_008760 {REF} {Length: 1051} {RNA1310_75395.1} {RNA815_42524}
68. MligTC455_19275 407 8.47 Mlig455_037548

Neo: -

Age: logFC(26M/2M)=0.488

Region-enriched R2: 3.247/0.04164

CHRNA10 2.721 0.863 - - 0.988 0.870 - Mlig455_037548 {REF} {Length: 959} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=87.9]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=96.7, Expect=1e-22]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=97.1, Expect=7e-23]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=95.1, Expect=5e-22]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=110, Expect=1e-27]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=119, Expect=8e-31]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=93.2, Expect=1e-21]} {RNA1509_23115} {RNA1310_34970} {RNA815_15305.1}
69. MligTC455_45769 79 1.65 Mlig455_018116

Neo: -

Age: -

2.72 - - 0.847 0.984 0.889 - Mlig455_018116 {REF} {Length: 3312} {Pfam: NACHT domain [PF05729.14, score=33.6]; AAA ATPase domain [PF13191.8, score=25.1]; AAA domain [PF13401.8, score=19.4]} {Smed: dd_Smed_v6_9074_0_1, dd_Smed_v6_9074_0_1, [Score=138, Expect=2e-33]} {RNA1509_44893} {RNA1310_38241} {RNA815_33748}
70. MligTC455_28693 60 1.26 Mlig455_022354

Neo: -

Age: -

2.712 - - 0.977 0.913 0.822 - Mlig455_022354 {REF} {Length: 816} {Pfam: WSC domain [PF01822.21, score=53.0]; PAN domain [PF00024.28, score=20.6]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=48.1, Expect=2e-06]} {RNA1509_43359} {RNA1310_59466.1} {RNA815_19988}
71. MligTC455_43326 39 0.8 Mlig455_057987

Neo: -

Age: -

2.708 0.835 - 0.976 0.897 - - Mlig455_057987 {REF} {Length: 1058} {RNA1310_129308}
72. MligTC455_51537 225 4.69 Mlig455_064569

Neo: -

Age: -

2.706 - - 0.971 0.981 0.754 - Mlig455_064569 {REF} {Length: 2141} {RNA1310_34295.1} {RNA815_22630}
73. MligTC455_22214 237 4.94 Mlig455_019333, Mlig455_019447

Neo: -

Age: -

NRG2 2.702 - - - 0.974 0.932 0.796

Mlig455_019333 {REF} {Length: 4291} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=50.5]; Immunoglobulin domain [PF13927.8, score=44.7]; Immunoglobulin domain [PF00047.27, score=43.9]; Immunoglobulin domain [PF13895.8, score=22.0]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=86.7, Expect=8e-17]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [RH, Score=81.3, Expect=2e-15]} {Dmel: FBgn0005666, bt, bent, [Score=52.0, Expect=2e-06]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=51.2, Expect=3e-06]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [Score=55.1, Expect=9e-08]} {RNA1509_54517} {RNA1310_8322} {RNA815_13786}

Mlig455_019447 {REF} {Length: 4242} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=50.5]; Immunoglobulin domain [PF13927.8, score=44.8]; Immunoglobulin domain [PF00047.27, score=43.9]; Immunoglobulin domain [PF13895.8, score=22.1]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=18.6]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=88.6, Expect=2e-17]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [RH, Score=83.2, Expect=7e-16]} {Dmel: FBgn0005666, bt, bent, [Score=52.4, Expect=2e-06]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=51.2, Expect=3e-06]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [Score=55.1, Expect=9e-08]} {RNA1509_54517} {RNA1310_8322} {RNA815_13786}
74. MligTC455_31163 72 1.51 Mlig455_045625

Neo: -

Age: Up-Down-Down

2.697 - - 0.971 0.890 0.836 - Mlig455_045625 {REF} {Length: 1957} {RNA1509_21720} {RNA1310_14760, RNA1509_21720} {RNA1509_21720, RNA815_24583}
75. MligTC455_40872 71 1.48 Mlig455_029550, Mlig455_040459, Mlig455_043605

Neo: -

Age: -

2.687 - - 0.985 0.891 0.811 -

Mlig455_029550 {REF} {Length: 1370} {Pfam: Globin [PF00042.24, score=35.2]} {RNA1310_33016} {RNA815_22300}

Mlig455_040459 {REF} {Length: 1083} {Pfam: Globin [PF00042.24, score=53.9]} {RNA1310_33016} {RNA815_22300}

Mlig455_043605 {REF} {Length: 1424} {Pfam: Globin [PF00042.24, score=53.9]} {RNA1509_4190} {RNA1310_33016} {RNA815_22300}
76. MligTC455_47393 241 5.03 Mlig455_008718, Mlig455_063579

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.683/0.00849

CALM2 2.685 0.832 - - 0.893 0.960 -

Mlig455_008718 {REF} {Length: 1727} {Pfam: EF hand [PF00036.34, score=99.3]; EF-hand domain pair [PF13499.8, score=95.1]; EF-hand domain [PF13405.8, score=86.1]; EF-hand domain pair [PF13833.8, score=76.8]; EF hand [PF13202.8, score=75.3]; EF-hand domain [PF14658.8, score=46.0]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.9]; EF-hand domain [PF08976.13, score=23.4]; Uncharacterised protein family (UPF0154) [PF03672.15, score=18.7]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=108, Expect=4e-30]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=4e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=4e-30]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-30]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=108, Expect=2e-30]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=1e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-30]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-30]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=114, Expect=8e-33]} {RNA1310_33847.1} {RNA815_17211}

Mlig455_063579 {REF} {Length: 2562} {Pfam: EF hand [PF00036.34, score=95.8]; EF-hand domain pair [PF13499.8, score=92.8]; EF-hand domain [PF13405.8, score=82.9]; EF-hand domain pair [PF13833.8, score=74.4]; EF hand [PF13202.8, score=72.2]; EF-hand domain [PF14658.8, score=43.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.6]; EF-hand domain [PF08976.13, score=21.4]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=111, Expect=7e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=3e-29]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=3e-29]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=111, Expect=7e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-29]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-29]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=9e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-29]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-29]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=111, Expect=9e-31]} {RNA1310_12431.1} {RNA815_17211}
77. MligTC455_33040 203 4.23 Mlig455_032497

Neo: -

Age: logFC(26M/2M)=0.515

Region-enriched R2: 4.005/0.00408

PKD2L1 2.682 - - 0.992 0.980 0.710 - Mlig455_032497 {REF} {Length: 3318} {Pfam: Polycystin cation channel [PF08016.14, score=293.1]; Ion transport protein [PF00520.33, score=39.7]} {Human: ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [Score=236, Expect=4e-66]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=261, Expect=3e-73]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=131, Expect=5e-31]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=180, Expect=1e-47]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=641, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
78. MligTC455_48561 779 16.24 Mlig455_034702, Mlig455_034755

Neo: -

Age: -

FABP4 2.68 - - 0.904 0.962 - 0.814

Mlig455_034702 {REF} {Length: 723} {Human: ENSG00000170323, FABP4, fatty acid binding protein 4, [Score=43.9, Expect=8e-06]} {RNA1509_39777} {RNA1310_54956} {RNA815_27929.1}

Mlig455_034755 {REF} {Length: 924} {Human: ENSG00000170323, FABP4, fatty acid binding protein 4, [Score=43.9, Expect=8e-06]} {RNA1509_39777} {RNA1310_54956, RNA1509_39777} {RNA1509_39777, RNA815_27929.1}
79. MligTC455_41028 108 2.26 Mlig455_033278

Neo: -

Age: -

2.68 0.863 - 0.835 0.982 - - Mlig455_033278 {REF} {Length: 1134} {Pfam: PAN domain [PF00024.28, score=19.4]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=9e-14]} {RNA1310_31986} {RNA815_17816.2}
80. MligTC455_41226 44 0.92 Mlig455_019357, Mlig455_059122

Neo: -

Age: -

GALNT1 2.678 - - 0.977 0.777 0.924 -

Mlig455_019357 {REF} {Length: 1606} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=97.5]; Glycosyltransferase like family 2 [PF13641.8, score=38.9]; N-terminal domain of galactosyltransferase [PF02709.16, score=29.1]; Glycosyltransferase like family 2 [PF10111.11, score=18.5]} {Human: ENSG00000141429, GALNT1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=318, Expect=2e-103]; ENSG00000139629, GALNT6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=311, Expect=4e-100]; ENSG00000257594, GALNT4, polypeptide N-acetylgalactosaminyltransferase 4, [Score=305, Expect=3e-98]; ENSG00000259075, POC1B-GALNT4, POC1B-GALNT4 readthrough, [Score=305, Expect=3e-98]} {Mouse: ENSMUSG00000000420, Galnt1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=316, Expect=1e-102]; ENSMUSG00000037280, Galnt6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=308, Expect=9e-99]; ENSMUSG00000060988, Galnt13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=302, Expect=3e-97]} {Dmel: FBgn0050463, CG30463, [Score=345, Expect=5e-113]} {Celegans: WBGene00001630, gly-5, Polypeptide N-acetylgalactosaminyltransferase 5, [Score=350, Expect=3e-115]} {Smed: dd_Smed_v6_8580_0_1, dd_Smed_v6_8580_0_1, [Score=353, Expect=1e-117]} {RNA1310_25598} {RNA815_36943}

Mlig455_059122 {REF} {Length: 2150} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=96.4]; Glycosyltransferase like family 2 [PF13641.8, score=35.9]; N-terminal domain of galactosyltransferase [PF02709.16, score=29.5]} {Human: ENSG00000141429, GALNT1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=313, Expect=2e-101]; ENSG00000139629, GALNT6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=307, Expect=2e-98]; ENSG00000257594, GALNT4, polypeptide N-acetylgalactosaminyltransferase 4, [Score=300, Expect=6e-96]; ENSG00000259075, POC1B-GALNT4, POC1B-GALNT4 readthrough, [Score=299, Expect=7e-96]; ENSG00000144278, GALNT13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=298, Expect=1e-95]} {Mouse: ENSMUSG00000000420, Galnt1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=311, Expect=1e-100]; ENSMUSG00000037280, Galnt6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=305, Expect=1e-97]; ENSMUSG00000060988, Galnt13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=298, Expect=8e-96]; ENSMUSG00000026994, Galnt3, polypeptide N-acetylgalactosaminyltransferase 3, [Score=296, Expect=5e-94]; ENSMUSG00000026828, Galnt5, polypeptide N-acetylgalactosaminyltransferase 5, [Score=296, Expect=2e-91]} {Dmel: FBgn0050463, CG30463, [Score=340, Expect=3e-111]} {Celegans: WBGene00001630, gly-5, Polypeptide N-acetylgalactosaminyltransferase 5, [Score=344, Expect=3e-113]} {Smed: dd_Smed_v6_8580_0_1, dd_Smed_v6_8580_0_1, [Score=350, Expect=3e-116]} {RNA1310_25598} {RNA815_36943}
81. MligTC455_43528 1273 26.52 Mlig455_068411

Neo: -

Age: Down-Up-Up

2.676 - - 0.902 0.971 0.803 - Mlig455_068411 {REF} {Length: 842} {Pfam: Pancreatic hormone peptide [PF00159.20, score=37.0]} {RNA1509_15391, RNA1509_36078, RNA1509_47628} {RNA1310_43859, RNA1509_15391, RNA1509_36078, RNA1509_47628} {RNA1509_15391, RNA1509_36078, RNA1509_47628, RNA815_26881}
82. MligTC455_43390 28 0.59 Mlig455_064273

Neo: -

Age: Down-Up-Down

PRKAR2A 2.669 - - 0.942 0.969 0.758 - Mlig455_064273 {REF} {Length: 2394} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=122.5]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=40.5]} {Human: ENSG00000114302, PRKAR2A, protein kinase cAMP-dependent type II regulatory subunit alpha, [Score=305, Expect=2e-100]; ENSG00000005249, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, [Score=296, Expect=8e-97]; ENSG00000284096, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, [Score=296, Expect=8e-97]} {Mouse: ENSMUSG00000032601, Prkar2a, protein kinase, cAMP dependent regulatory, type II alpha, [Score=314, Expect=6e-104]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [Score=335, Expect=1e-112]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=219, Expect=2e-68]} {Smed: dd_Smed_v6_4188_0_1, dd_Smed_v6_4188_0_1, [Score=335, Expect=5e-113]} {RNA1509_34470} {RNA1310_27777} {RNA815_5628}
83. MligTC455_32409 155 3.23 Mlig455_049287, Mlig455_049300

Neo: -

Age: -

FOXG1 2.667 - - 0.973 0.832 0.862 -

Mlig455_049287 {REF} {Length: 1224} {Pfam: Forkhead domain [PF00250.20, score=130.8]} {Human: ENSG00000176165, FOXG1, forkhead box G1, [Score=192, Expect=1e-57]} {Mouse: ENSMUSG00000020950, Foxg1, forkhead box G1, [Score=194, Expect=3e-58]} {Dmel: FBgn0004567, slp2, sloppy paired 2, [Score=198, Expect=2e-60]} {Celegans: WBGene00001434, fkh-2, ForKHead transcription factor family, [RH, Score=190, Expect=2e-59]} {Smed: dd_Smed_v6_16466_0_1, dd_Smed_v6_16466_0_1, [Score=151, Expect=1e-45]} {RNA1310_31219} {RNA815_15954.1}

Mlig455_049300 {REF} {Length: 1162} {Pfam: Forkhead domain [PF00250.20, score=130.8]} {Human: ENSG00000176165, FOXG1, forkhead box G1, [Score=192, Expect=1e-57]} {Mouse: ENSMUSG00000020950, Foxg1, forkhead box G1, [Score=194, Expect=3e-58]} {Dmel: FBgn0004567, slp2, sloppy paired 2, [Score=198, Expect=2e-60]} {Celegans: WBGene00001434, fkh-2, ForKHead transcription factor family, [RH, Score=190, Expect=2e-59]} {Smed: dd_Smed_v6_16466_0_1, dd_Smed_v6_16466_0_1, [Score=151, Expect=1e-45]} {RNA1310_31219} {RNA815_15954.1}
84. MligTC455_11863 67 1.4 Mlig455_037840

Neo: -

Age: -

Region-enriched R7: 3.761/0.04261

GRM3 2.666 - - 0.952 0.897 0.817 - Mlig455_037840 {REF} {Length: 3733} {Pfam: Receptor family ligand binding region [PF01094.30, score=244.3]; 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=189.6]; Nine Cysteines Domain of family 3 GPCR [PF07562.16, score=36.4]} {Human: ENSG00000198822, GRM3, glutamate metabotropic receptor 3, [RH, Score=701, Expect=0.0]} {Mouse: ENSMUSG00000003974, Grm3, glutamate receptor, metabotropic 3, [RH, Score=699, Expect=0.0]} {Dmel: FBgn0019985, mGluR, metabotropic Glutamate Receptor, [RH, Score=766, Expect=0.0]} {Celegans: WBGene00003232, mgl-1, Probable metabotropic glutamate receptor mgl-1, [RH, Score=626, Expect=0.0]} {Smed: dd_Smed_v6_15419_0_1, dd_Smed_v6_15419_0_1, [RH, Score=818, Expect=0.0]} {RNA1310_32870} {RNA815_40865}
85. MligTC455_50532 259 5.4 Mlig455_019987

Neo: -

Age: Down-Up-Down

NEFH 2.665 0.836 - - 0.971 0.858 - Mlig455_019987 {REF} {Length: 4055} {Human: ENSG00000100285, NEFH, neurofilament heavy, [Score=65.5, Expect=3e-10]} {RNA1509_41200, RNA1509_57173} {RNA1310_3614.2, RNA1509_41200, RNA1509_57173} {RNA1509_41200, RNA1509_57173, RNA815_5328}
86. MligTC455_46394 8810 183.54 Mlig455_054818, Mlig455_054826

Neo: -

Age: -

Region-specific R2: 1.771

Region-enriched R2: 1.255/0.00038

PKD2 2.664 - - 0.846 0.971 0.847 -

Mlig455_054818 {REF} {Length: 2992} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=747, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=380, Expect=6e-120]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [Score=733, Expect=0.0]} {RNA1509_1615} {RNA1310_21296.2, RNA1509_1615} {RNA1509_1615, RNA815_3158.1}

Mlig455_054826 {REF} {Length: 3118} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.4]; EF hand [PF00036.34, score=32.6]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=754, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=751, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=2e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=1e-122]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
87. MligTC455_53190 105 2.18 Mlig455_013516

Neo: -

Age: -

SCNN1B 2.658 - - 0.838 0.953 0.867 - Mlig455_013516 {REF} {Length: 2819} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=290.8]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=158, Expect=8e-41]} {Mouse: ENSMUSG00000000216, Scnn1g, sodium channel, nonvoltage-gated 1 gamma, [Score=149, Expect=1e-37]} {Dmel: FBgn0051105, ppk22, pickpocket 22, [RH, Score=60.1, Expect=3e-09]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [RH, Score=166, Expect=2e-43]} {Smed: dd_Smed_v6_17021_0_1, dd_Smed_v6_17021_0_1, [RH, Score=186, Expect=1e-51]} {RNA1509_18670} {RNA1310_20526} {RNA815_9932}
88. MligTC455_20390 87 1.82 Mlig455_051716

Neo: -

Age: -

SLC1A2 2.657 - - 0.956 0.851 0.850 - Mlig455_051716 {REF} {Length: 4683} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=432.6]} {Human: ENSG00000110436, SLC1A2, solute carrier family 1 member 2, [RH, Score=530, Expect=0.0]} {Mouse: ENSMUSG00000005089, Slc1a2, solute carrier family 1 (glial high affinity glutamate transporter), member 2, [RH, Score=545, Expect=0.0]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=375, Expect=4e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [RH, Score=517, Expect=1e-179]} {Smed: dd_Smed_v6_7570_0_1, dd_Smed_v6_7570_0_1, [RH, Score=611, Expect=0.0]} {RNA1509_31315} {RNA1310_5180} {RNA815_8754}
89. MligTC455_49296 69 1.44 Mlig455_034352, Mlig455_034414

Neo: -

Age: -

2.644 - - 0.965 0.771 0.908 -

Mlig455_034352 {REF} {Length: 912} {TRANSSPLICED}

Mlig455_034414 {REF} {Length: 919} {TRANSSPLICED}
90. MligTC455_29510 1443 30.06 Mlig455_003367, Mlig455_003369

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.360

Region-enriched R8: 1.897/0.00063
Region-enriched R7: 1.375/0.01086

Regeneration-downregulated BL: -2.492

Regeneration-depleted BL: -2.492

2.643 - - 0.790 0.967 0.886 -

Mlig455_003367 {REF} {Length: 1906} {Pfam: Interferon-induced 6-16 family [PF06140.15, score=25.4]} {RNA1509_46297} {RNA1310_31671} {RNA815_28401}

Mlig455_003369 {REF} {Length: 1024} {RNA1509_28087, RNA1509_46297} {RNA1310_31671, RNA1509_28087, RNA1509_46297} {RNA1509_28087, RNA1509_46297, RNA815_17641.1}
91. MligTC455_50288 118 2.47 Mlig455_059182

Neo: -

Age: Up-Down-Down

2.638 0.832 - 0.966 - 0.840 - Mlig455_059182 {REF} {Length: 3438} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=42.6]; Lectin C-type domain [PF00059.23, score=23.6]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [RH, Score=189, Expect=3e-53]} {RNA1509_45950, RNA1509_54781} {RNA1310_10757.1, RNA1509_45950, RNA1509_54781} {RNA1509_45950, RNA1509_54781, RNA815_5369}
92. MligTC455_04162 131 2.73 Mlig455_028924

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.575

HMCN1 2.636 - - - 0.991 0.925 0.720 Mlig455_028924 {REF} {Length: 3929} {Pfam: Immunoglobulin domain [PF13927.8, score=144.9]; Immunoglobulin I-set domain [PF07679.18, score=119.8]; Immunoglobulin domain [PF13895.8, score=113.4]; Immunoglobulin domain [PF00047.27, score=102.3]; Immunoglobulin V-set domain [PF07686.19, score=36.7]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=35.3]; Immunoglobulin C1-set domain [PF07654.17, score=23.3]; C17orf99 Ig domain [PF17736.3, score=20.9]; Immunoglobulin domain [PF18452.3, score=19.8]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=103, Expect=2e-21]; ENSG00000148357, HMCN2, hemicentin 2, [Score=100, Expect=8e-21]} {Mouse: ENSMUSG00000051747, Ttn, titin, [Score=107, Expect=5e-23]; ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=103, Expect=7e-22]} {Dmel: FBgn0000547, ed, echinoid, [Score=147, Expect=2e-35]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=100, Expect=3e-21]} {Smed: dd_Smed_v6_13903_0_1, dd_Smed_v6_13903_0_1, [Score=162, Expect=2e-40]} {RNA1310_26618} {RNA815_41641}
93. MligTC455_24441 37 0.76 Mlig455_029687, Mlig455_034829

Neo: -

Age: -

2.633 0.860 - 0.979 - 0.794 -

Mlig455_029687 {REF} {Length: 1968} {TRANSSPLICED} {RNA1310_30797} {RNA815_37394}

Mlig455_034829 {REF} {Length: 2468} {RNA1310_30797} {RNA815_37606}
94. MligTC455_52727 82 1.72 Mlig455_043336

Neo: -

Age: Down-Up-Down

2.632 0.869 - 0.808 - 0.955 - Mlig455_043336 {REF} {Length: 1410} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=60.5]; Capsular polysaccharide synthesis protein [PF05704.14, score=20.9]} {Smed: dd_Smed_v6_6819_0_1, dd_Smed_v6_6819_0_1, [Score=131, Expect=4e-35]} {RNA1509_41314} {RNA1310_26265} {RNA815_9794.1}
95. MligTC455_35259 2265 47.19 Mlig455_040978

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.606

Region-enriched R2: 1.588/0.00387

ADGRL2 2.632 - - 0.834 0.973 0.825 - Mlig455_040978 {REF} {Length: 10808} {TRANSSPLICED} {Pfam: PDZ domain [PF00595.26, score=86.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=76.2]; PDZ domain [PF17820.3, score=67.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=52.3]; PDZ domain [PF13180.8, score=36.4]; ZU5 domain [PF00791.22, score=30.8]; Guanylate kinase [PF00625.23, score=22.4]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [RH, Score=174, Expect=1e-42]} {Mouse: ENSMUSG00000034917, Tjp3, tight junction protein 3, [RH, Score=172, Expect=9e-43]} {Dmel: FBgn0262614, pyd, polychaetoid, [RH, Score=232, Expect=8e-61]} {Celegans: WBGene00013683, zoo-1, ZO-1 (Zonula Occludens tight junctional protein) Ortholog, [Score=174, Expect=4e-43]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [RH, Score=833, Expect=0.0]} {RNA1509_17602, RNA1509_52679, RNA1509_58629} {RNA1310_236.2, RNA1509_17602, RNA1509_58629} {RNA1509_17602, RNA1509_58629, RNA815_77.1}
96. MligTC455_52349 99 2.06 Mlig455_011056

Neo: -

Age: -

DGKI 2.628 - - 0.951 0.804 0.873 - Mlig455_011056 {REF} {Length: 3706} {Pfam: Diacylglycerol kinase accessory domain [PF00609.21, score=146.1]; Diacylglycerol kinase catalytic domain [PF00781.26, score=101.1]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=31.0]; Proline-rich protein family 20 [PF15708.7, score=21.0]} {Human: ENSG00000157680, DGKI, diacylglycerol kinase iota, [Score=677, Expect=0.0]; ENSG00000149091, DGKZ, diacylglycerol kinase zeta, [Score=672, Expect=0.0]} {Mouse: ENSMUSG00000038665, Dgki, diacylglycerol kinase, iota, [Score=682, Expect=0.0]; ENSMUSG00000040479, Dgkz, diacylglycerol kinase zeta, [Score=667, Expect=0.0]} {Dmel: FBgn0261549, rdgA, retinal degeneration A, [Score=533, Expect=8e-173]} {Celegans: WBGene00019428, dgk-5, Putative diacylglycerol kinase K06A1.6, [RH, Score=491, Expect=4e-158]} {Smed: dd_Smed_v6_12579_0_4, dd_Smed_v6_12579_0_4, [Score=629, Expect=0.0]} {RNA1509_51540} {RNA1310_9558, RNA1509_51540} {RNA1509_51540, RNA815_11195}
97. MligTC455_40657 90 1.87 Mlig455_040779

Neo: -

Age: -

CLIP2 2.619 0.765 - - 0.969 0.885 - Mlig455_040779 {REF} {Length: 2164} {Pfam: CAP-Gly domain [PF01302.27, score=60.7]} {Human: ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000063146, Clip2, CAP-GLY domain containing linker protein 2, [Score=62.0, Expect=1e-09]} {Dmel: FBgn0036882, CG9279, [Score=54.7, Expect=1e-07]} {Smed: dd_Smed_v6_12985_0_1, dd_Smed_v6_12985_0_1, [Score=56.2, Expect=2e-08]} {RNA1310_20676} {RNA815_40746}
98. MligTC455_54202 381 7.94 Mlig455_006349

Neo: -

Age: logFC(26M/2M)=0.343

Region-specific R2: 5.916

Region-enriched R2: 5.229/0.00037

MYH6 2.607 0.749 - - 0.893 0.965 - Mlig455_006349 {REF} {Length: 6943} {Pfam: Myosin head (motor domain) [PF00063.23, score=929.0]; Myosin tail [PF01576.21, score=591.7]; Myosin N-terminal SH3-like domain [PF02736.21, score=60.7]; Crescentin protein [PF19220.2, score=26.4]; Autophagy protein 16 (ATG16) [PF08614.13, score=20.3]; Macoilin family [PF09726.11, score=18.3]} {Human: ENSG00000197616, MYH6, myosin heavy chain 6, [RH, Score=2075, Expect=0.0]; ENSG00000092054, MYH7, myosin heavy chain 7, [RH, Score=2066, Expect=0.0]; ENSG00000125414, MYH2, myosin heavy chain 2, [RH, Score=2021, Expect=0.0]; ENSG00000109061, MYH1, myosin heavy chain 1, [RH, Score=2013, Expect=0.0]; ENSG00000133020, MYH8, myosin heavy chain 8, [RH, Score=2007, Expect=0.0]; ENSG00000264424, MYH4, myosin heavy chain 4, [RH, Score=1993, Expect=0.0]; ENSG00000109063, MYH3, myosin heavy chain 3, [RH, Score=1974, Expect=0.0]} {Mouse: ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [RH, Score=2076, Expect=0.0]; ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [RH, Score=2063, Expect=0.0]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [RH, Score=2041, Expect=0.0]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [RH, Score=2018, Expect=0.0]; ENSMUSG00000055775, Myh8, myosin, heavy polypeptide 8, skeletal muscle, perinatal, [RH, Score=2015, Expect=0.0]; ENSMUSG00000033196, Myh2, myosin, heavy polypeptide 2, skeletal muscle, adult, [RH, Score=2009, Expect=0.0]; ENSMUSG00000020908, Myh3, myosin, heavy polypeptide 3, skeletal muscle, embryonic, [RH, Score=1981, Expect=0.0]; ENSMUSG00000060180, Myh13, myosin, heavy polypeptide 13, skeletal muscle, [RH, Score=1979, Expect=0.0]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [RH, Score=2100, Expect=0.0]} {Celegans: WBGene00019064, myo-5, MYOsin heavy chain structural genes, [RH, Score=1996, Expect=0.0]} {Smed: dd_Smed_v6_579_0_1, dd_Smed_v6_579_0_1, [RH, Score=2705, Expect=0.0]} {RNA1509_16048, RNA1509_54239, RNA1509_55838} {RNA1310_1388, RNA1509_16048, RNA1509_54239, RNA1509_55838} {RNA1509_16048, RNA1509_54239, RNA1509_55838, RNA815_129.1}
99. MligTC455_46691 41 0.85 Mlig455_018781, Mlig455_018951

Neo: -

Age: Up-Down-Down

2.606 0.714 - 0.950 0.942 - -

Mlig455_018781 {REF} {Length: 1694} {Celegans: WBGene00021142, clec-133, C-type LECtin, [RH, Score=52.0, Expect=6e-08]} {RNA1310_43489} {RNA815_41340}

Mlig455_018951 {REF} {Length: 2466} {Celegans: WBGene00021142, clec-133, C-type LECtin, [RH, Score=52.0, Expect=6e-08]} {RNA1310_38733.1} {RNA815_41340}
100. MligTC455_22323 68 1.42 Mlig455_000713, Mlig455_000766

Neo: -

Age: -

HCN4 2.603 0.765 - 0.951 - 0.887 -

Mlig455_000713 {REF} {Length: 3555} {Pfam: Ion transport protein N-terminal [PF08412.12, score=83.6]; Cyclic nucleotide-binding domain [PF00027.31, score=70.8]; Ion transport protein [PF00520.33, score=62.7]} {Human: ENSG00000138622, HCN4, hyperpolarization activated cyclic nucleotide gated potassium channel 4, [Score=581, Expect=0.0]; ENSG00000099822, HCN2, hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2, [Score=568, Expect=0.0]} {Mouse: ENSMUSG00000032338, Hcn4, hyperpolarization-activated, cyclic nucleotide-gated K+ 4, [Score=579, Expect=0.0]; ENSMUSG00000020331, Hcn2, hyperpolarization-activated, cyclic nucleotide-gated K+ 2, [Score=563, Expect=0.0]} {Dmel: FBgn0263397, Ih, I[[h]] channel, [RH, Score=512, Expect=1e-161]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [Score=133, Expect=8e-32]} {Smed: dd_Smed_v6_16523_0_1, dd_Smed_v6_16523_0_1, [Score=859, Expect=0.0]} {RNA1509_59211} {RNA1310_33761} {RNA815_15561.1}

Mlig455_000766 {REF} {Length: 4037} {Pfam: Ion transport protein N-terminal [PF08412.12, score=83.5]; Cyclic nucleotide-binding domain [PF00027.31, score=70.7]; Ion transport protein [PF00520.33, score=62.6]} {Human: ENSG00000138622, HCN4, hyperpolarization activated cyclic nucleotide gated potassium channel 4, [Score=566, Expect=0.0]; ENSG00000099822, HCN2, hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2, [Score=553, Expect=0.0]} {Mouse: ENSMUSG00000032338, Hcn4, hyperpolarization-activated, cyclic nucleotide-gated K+ 4, [Score=564, Expect=0.0]; ENSMUSG00000020331, Hcn2, hyperpolarization-activated, cyclic nucleotide-gated K+ 2, [Score=548, Expect=3e-180]} {Dmel: FBgn0263397, Ih, I[[h]] channel, [Score=502, Expect=4e-166]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [Score=133, Expect=8e-32]} {Smed: dd_Smed_v6_16523_0_1, dd_Smed_v6_16523_0_1, [Score=844, Expect=0.0]} {RNA1509_59211} {RNA1310_33761} {RNA815_15561.1}

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