Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_37871 | 805 | 16.78 | Mlig455_004524 | Neo: - Age: Up-Down-Up Region-specific R4: 1.756 Region-enriched R4: 2.463/0.00000 Regeneration-upregulated TP: 2.142 Regeneration-enriched TP: 2.142 |
HMGB1 | Mlig455_004524 {REF} {Length: 3515} {Pfam: HMG (high mobility group) box [PF00505.21, score=130.7]; HMG-box domain [PF09011.12, score=110.0]} {Human: ENSG00000189403, HMGB1, high mobility group box 1, [Score=167, Expect=8e-52]; ENSG00000164104, HMGB2, high mobility group box 2, [Score=161, Expect=1e-49]} {Mouse: ENSMUSG00000066551, Hmgb1, high mobility group box 1, [RH, Score=162, Expect=1e-50]} {Dmel: FBgn0278608, Dsp1, Dorsal switch protein 1, [Score=187, Expect=3e-58]} {Celegans: WBGene00001972, hmg-1.2, High mobility group protein 1.2, [Score=147, Expect=2e-44]} {Smed: dd_Smed_v6_1331_0_1, dd_Smed_v6_1331_0_1, [RH, Score=237, Expect=5e-79]} {RNA1509_561} {RNA1310_15889.1} {RNA815_4632} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 0.395 | 4.277 | 0.71456 | 1.00000 | |
RegionR2 | -0.597 | 4.277 | 0.19996 | 0.56044 | |
RegionR3 | -0.094 | 4.277 | 0.81093 | 1.00000 | |
RegionR4 | 2.463 | 4.277 | 0.00000 | 0.00000 | Specific for R4: 1.756 |
RegionR5 | -0.167 | 4.277 | 0.65382 | 1.00000 | |
RegionR6 | -0.387 | 4.277 | 0.34182 | 0.92878 | |
RegionR7 | -0.588 | 4.277 | 0.27866 | 0.91073 | |
RegionR8 | -1.025 | 4.277 | 0.14703 | 0.69881 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 0.541 | 4.277 | 0.66979 | 1.00000 | |
RegenerationR2 | -0.267 | 4.277 | 0.51984 | 0.87915 | |
RegenerationR3 | -0.227 | 4.277 | 0.60982 | 0.91265 | |
RegenerationR4 | -1.548 | 4.277 | 0.00036 | 0.01713 | |
RegenerationR5 | 0.239 | 4.277 | 0.56707 | 0.89506 | |
RegenerationR6 | 0.656 | 4.277 | 0.15129 | 0.47667 | |
RegenerationBL | 0.778 | 4.277 | 0.14882 | 0.46095 | |
RegenerationTP | 2.142 | 4.277 | 0.00005 | 0.00718 | Specific for TP: 2.142 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_37871 | 805 | 16.78 | Mlig455_004524 | Neo: - Age: Up-Down-Up Region-specific R4: 1.756 Region-enriched R4: 2.463/0.00000 Regeneration-upregulated TP: 2.142 Regeneration-enriched TP: 2.142 |
HMGB1 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_004524 {REF} {Length: 3515} {Pfam: HMG (high mobility group) box [PF00505.21, score=130.7]; HMG-box domain [PF09011.12, score=110.0]} {Human: ENSG00000189403, HMGB1, high mobility group box 1, [Score=167, Expect=8e-52]; ENSG00000164104, HMGB2, high mobility group box 2, [Score=161, Expect=1e-49]} {Mouse: ENSMUSG00000066551, Hmgb1, high mobility group box 1, [RH, Score=162, Expect=1e-50]} {Dmel: FBgn0278608, Dsp1, Dorsal switch protein 1, [Score=187, Expect=3e-58]} {Celegans: WBGene00001972, hmg-1.2, High mobility group protein 1.2, [Score=147, Expect=2e-44]} {Smed: dd_Smed_v6_1331_0_1, dd_Smed_v6_1331_0_1, [RH, Score=237, Expect=5e-79]} {RNA1509_561} {RNA1310_15889.1} {RNA815_4632} |
2. | MligTC455_52583 | 14 | 0.3 | Mlig455_027358 | Neo: Germline Age: Down-Up-Down |
TRPA1 | 0.975 | - | 0.975 | - | - | - | - | Mlig455_027358 {REF} {Length: 2596} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=63.9]; Ankyrin repeats (3 copies) [PF12796.9, score=62.4]; Ankyrin repeat [PF13606.8, score=54.3]; Ankyrin repeat [PF00023.32, score=51.2]; Ankyrin repeats (many copies) [PF13857.8, score=49.6]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=66.2, Expect=6e-12]; ENSG00000101843, PSMD10, proteasome 26S subunit, non-ATPase 10, [Score=64.3, Expect=2e-12]} {Mouse: ENSMUSG00000031429, Psmd10, proteasome (prosome, macropain) 26S subunit, non-ATPase, 10, [Score=62.8, Expect=5e-12]; ENSMUSG00000116430, Psmd10, proteasome (prosome, macropain) 26S subunit, non-ATPase, 10, [Score=62.8, Expect=5e-12]; ENSMUSG00000032257, Ankk1, ankyrin repeat and kinase domain containing 1, [Score=59.7, Expect=6e-10]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=64.3, Expect=1e-11]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=54.3, Expect=3e-08]} {Smed: dd_Smed_v6_2072_0_22, dd_Smed_v6_2072_0_22, [Score=64.3, Expect=9e-12]} {RNA1509_31030} {RNA1310_28556} {RNA815_46814} |
3. | MligTC455_41805 | 2256 | 47 | Mlig455_015764, Mlig455_049489 | Neo: - Age: - Region-specific R8: 2.792 Region-enriched R8: 2.927/0.00000 |
PKD2 | 0.958 | - | - | - | - | - | 0.958 | Mlig455_015764 {REF} {Length: 3347} {Pfam: Polycystin cation channel [PF08016.14, score=395.7]; Ion transport protein [PF00520.33, score=60.8]; EF hand [PF00036.34, score=22.8]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=20.9]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [Score=618, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [Score=617, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=255, Expect=3e-72]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=338, Expect=2e-104]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [Score=660, Expect=0.0]} {RNA1509_31010} {RNA1310_4653.2} {RNA815_18688} Mlig455_049489 {REF} {Length: 3379} {Pfam: Polycystin cation channel [PF08016.14, score=493.3]; Ion transport protein [PF00520.33, score=89.5]; EF hand [PF00036.34, score=27.1]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=20.9]; EF-hand domain [PF13405.8, score=18.5]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=716, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=711, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=306, Expect=1e-90]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [RH, Score=387, Expect=1e-122]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [RH, Score=739, Expect=0.0]} {RNA1509_31010, RNA1509_51627} {RNA1310_4653.1, RNA1509_31010, RNA1509_51627} {RNA1509_31010, RNA1509_51627, RNA815_4316} |
4. | MligTC455_26733 | 169 | 3.53 | Mlig455_034185 | Neo: Germline Age: Up-Down-Down, logFC(26M/2M)=-0.300 Region-enriched R4: 3.949/0.00126 Regeneration-downregulated R4: -4.371 Regeneration-depleted R4: -4.371 |
0.954 | - | 0.954 | - | - | - | - | Mlig455_034185 {REF} {Length: 1821} {RNA1509_55538, RNA1509_6125} {RNA1310_19758.1, RNA1509_55538} {RNA1509_55538, RNA815_7336} | |
5. | MligTC455_39334 | 1606 | 33.46 | Mlig455_052203 | Neo: - Age: - Region-enriched R5: 1.064/0.00073 |
RAP1B | 0.954 | - | - | - | - | 0.954 | - | Mlig455_052203 {REF} {Length: 1239} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=196.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=75.0]; ADP-ribosylation factor family [PF00025.23, score=37.2]; RsgA GTPase [PF03193.18, score=25.7]; Elongation factor Tu GTP binding domain [PF00009.29, score=23.1]; 50S ribosome-binding GTPase [PF01926.25, score=20.0]} {Human: ENSG00000127314, RAP1B, RAP1B, member of RAS oncogene family, [RH, Score=306, Expect=2e-107]; ENSG00000116473, RAP1A, RAP1A, member of RAS oncogene family, [RH, Score=300, Expect=7e-105]} {Mouse: ENSMUSG00000052681, Rap1b, RAS related protein 1b, [RH, Score=306, Expect=2e-107]; ENSMUSG00000068798, Rap1a, RAS-related protein 1a, [RH, Score=300, Expect=5e-105]} {Dmel: FBgn0004636, Rap1, Rap1 GTPase, [RH, Score=293, Expect=3e-102]} {Celegans: WBGene00004307, rap-1, Ras-related protein Rap-1, [RH, Score=295, Expect=2e-103]} {Smed: dd_Smed_v6_1239_0_1, dd_Smed_v6_1239_0_1, [RH, Score=302, Expect=3e-106]} {RNA1509_14132, RNA1509_24825} {RNA1310_27332, RNA1509_14132, RNA1509_24825} {RNA1509_14132, RNA1509_24825, RNA815_12569} |
6. | MligTC455_19993 | 205 | 4.27 | Mlig455_059684 | Neo: Germline Age: Up-Down-Down Region-specific R4: 5.259 |
KLHL10 | 0.953 | - | 0.953 | - | - | - | - | Mlig455_059684 {REF} {Length: 3178} {Pfam: Kelch motif [PF01344.27, score=49.0]; BTB And C-terminal Kelch [PF07707.17, score=40.4]; Kelch motif [PF07646.17, score=24.8]; BTB/POZ domain [PF00651.33, score=19.0]} {Human: ENSG00000161594, KLHL10, kelch like family member 10, [Score=68.2, Expect=3e-11]; ENSG00000114796, KLHL24, kelch like family member 24, [Score=67.4, Expect=5e-11]} {Mouse: ENSMUSG00000044938, Klhl31, kelch-like 31, [Score=83.2, Expect=4e-16]} {Dmel: FBgn0001301, kel, kelch, [Score=64.3, Expect=2e-10]} {Smed: dd_Smed_v6_1751_0_1, dd_Smed_v6_1751_0_1, [Score=54.3, Expect=1e-07]} {RNA1509_22536} {RNA1310_7097} {RNA815_20881} |
7. | MligTC455_54289 | 3802 | 79.2 | Mlig455_012605 | Neo: Int S/G2/M Age: Down-Up-Up |
GLRX5 | 0.952 | - | - | - | - | 0.952 | - | Mlig455_012605 {REF} {Length: 717} {TRANSSPLICED} {Pfam: Glutaredoxin [PF00462.26, score=63.7]} {Human: ENSG00000182512, GLRX5, glutaredoxin 5, [RH, Score=166, Expect=1e-52]} {Mouse: ENSMUSG00000021102, Glrx5, glutaredoxin 5, [RH, Score=168, Expect=5e-54]} {Dmel: FBgn0030584, CG14407, [RH, Score=164, Expect=2e-52]} {Celegans: WBGene00013029, glrx-5, Glutaredoxin, [RH, Score=120, Expect=2e-35]} {Smed: dd_Smed_v6_4134_0_1, dd_Smed_v6_4134_0_1, [RH, Score=144, Expect=7e-45]} {RNA1509_16692, RNA1509_4167} {RNA1310_49219, RNA1509_16692, RNA1509_4167} {RNA1509_16692, RNA1509_4167, RNA815_23644.1} |
8. | MligTC455_27717 | 2460 | 51.24 | Mlig455_034360 | Neo: - |
ACTG1 | 0.951 | - | - | - | - | - | 0.951 | Mlig455_034360 {REF} {Length: 1754} {Pfam: Actin [PF00022.21, score=499.7]} {Human: ENSG00000184009, ACTG1, actin gamma 1, [RH, Score=769, Expect=0.0]; ENSG00000075624, ACTB, actin beta, [RH, Score=769, Expect=0.0]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [RH, Score=746, Expect=0.0]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [RH, Score=745, Expect=0.0]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [RH, Score=744, Expect=0.0]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [RH, Score=741, Expect=0.0]; ENSG00000169067, ACTBL2, actin, beta like 2, [RH, Score=733, Expect=0.0]} {Mouse: ENSMUSG00000029580, Actb, actin, beta, [RH, Score=769, Expect=0.0]; ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [RH, Score=769, Expect=0.0]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [RH, Score=746, Expect=0.0]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [RH, Score=745, Expect=0.0]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [RH, Score=744, Expect=0.0]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [RH, Score=741, Expect=0.0]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [RH, Score=739, Expect=0.0]} {Dmel: FBgn0000042, Act5C, Actin 5C, [RH, Score=770, Expect=0.0]} {Celegans: WBGene00000066, act-4, Actin-4, [RH, Score=769, Expect=0.0]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [RH, Score=759, Expect=0.0]} {RNA1509_819} {RNA1310_20267.2} {RNA815_4929.3} |
9. | MligTC455_27718 | 2898 | 60.36 | Mlig455_017369, Mlig455_017453, Mlig455_030941, Mlig455_038743 | Neo: - |
ACTG1 | 0.951 | - | - | - | - | - | 0.951 | Mlig455_017369 {REF} {Length: 1755} {Pfam: Actin [PF00022.21, score=499.7]} {Human: ENSG00000184009, ACTG1, actin gamma 1, [RH, Score=769, Expect=0.0]; ENSG00000075624, ACTB, actin beta, [RH, Score=769, Expect=0.0]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [RH, Score=746, Expect=0.0]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [RH, Score=745, Expect=0.0]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [RH, Score=744, Expect=0.0]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [RH, Score=741, Expect=0.0]; ENSG00000169067, ACTBL2, actin, beta like 2, [RH, Score=733, Expect=0.0]} {Mouse: ENSMUSG00000029580, Actb, actin, beta, [RH, Score=769, Expect=0.0]; ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [RH, Score=769, Expect=0.0]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [RH, Score=746, Expect=0.0]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [RH, Score=745, Expect=0.0]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [RH, Score=744, Expect=0.0]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [RH, Score=741, Expect=0.0]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [RH, Score=739, Expect=0.0]} {Dmel: FBgn0000042, Act5C, Actin 5C, [RH, Score=770, Expect=0.0]} {Celegans: WBGene00000066, act-4, Actin-4, [RH, Score=769, Expect=0.0]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [RH, Score=759, Expect=0.0]} {RNA1509_819} {RNA1310_20267.2} {RNA815_4929.3} Mlig455_017453 {REF} {Length: 1755} {Pfam: Actin [PF00022.21, score=499.7]} {Human: ENSG00000184009, ACTG1, actin gamma 1, [RH, Score=769, Expect=0.0]; ENSG00000075624, ACTB, actin beta, [RH, Score=769, Expect=0.0]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [RH, Score=746, Expect=0.0]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [RH, Score=745, Expect=0.0]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [RH, Score=744, Expect=0.0]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [RH, Score=741, Expect=0.0]; ENSG00000169067, ACTBL2, actin, beta like 2, [RH, Score=733, Expect=0.0]} {Mouse: ENSMUSG00000029580, Actb, actin, beta, [RH, Score=769, Expect=0.0]; ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [RH, Score=769, Expect=0.0]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [RH, Score=746, Expect=0.0]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [RH, Score=745, Expect=0.0]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [RH, Score=744, Expect=0.0]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [RH, Score=741, Expect=0.0]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [RH, Score=739, Expect=0.0]} {Dmel: FBgn0000042, Act5C, Actin 5C, [RH, Score=770, Expect=0.0]} {Celegans: WBGene00000066, act-4, Actin-4, [RH, Score=769, Expect=0.0]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [RH, Score=759, Expect=0.0]} {RNA1509_819} {RNA1310_20267.2, RNA1509_819} {RNA1509_819, RNA815_4929.3} Mlig455_030941 {REF} {Length: 1755} {Pfam: Actin [PF00022.21, score=499.7]} {Human: ENSG00000184009, ACTG1, actin gamma 1, [RH, Score=769, Expect=0.0]; ENSG00000075624, ACTB, actin beta, [RH, Score=769, Expect=0.0]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [RH, Score=746, Expect=0.0]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [RH, Score=745, Expect=0.0]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [RH, Score=744, Expect=0.0]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [RH, Score=741, Expect=0.0]; ENSG00000169067, ACTBL2, actin, beta like 2, [RH, Score=733, Expect=0.0]} {Mouse: ENSMUSG00000029580, Actb, actin, beta, [RH, Score=769, Expect=0.0]; ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [RH, Score=769, Expect=0.0]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [RH, Score=746, Expect=0.0]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [RH, Score=745, Expect=0.0]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [RH, Score=744, Expect=0.0]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [RH, Score=741, Expect=0.0]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [RH, Score=739, Expect=0.0]} {Dmel: FBgn0000042, Act5C, Actin 5C, [RH, Score=770, Expect=0.0]} {Celegans: WBGene00000066, act-4, Actin-4, [RH, Score=769, Expect=0.0]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [RH, Score=759, Expect=0.0]} {RNA1509_19403, RNA1509_33717, RNA1509_819} {RNA1310_20267.2, RNA1509_19403, RNA1509_33717} {RNA1509_19403, RNA1509_33717, RNA815_4929.3} Mlig455_038743 {REF} {Length: 235} {RNA1310_23291.2} {RNA815_33940} |