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Results for MligTC455_38513

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_38513 2198 45.79 Mlig455_017355, Mlig455_030957

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.995

Mlig455_017355 {REF} {Length: 883} {NoTransDecoderORF} {RNA1509_15214, RNA1509_9249} {RNA1310_44691, RNA1509_15214, RNA1509_9249} {RNA1509_15214, RNA1509_9249, RNA815_20318.1}

Mlig455_030957 {REF} {Length: 881} {NoTransDecoderORF} {RNA1509_15214} {RNA1310_44691} {RNA815_20318.1}

Cumulative graph for MligTC455_38513

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.163 5.776 0.35728 0.99979
RegionR2 -0.328 5.776 0.68306 1.00000
RegionR3 0.099 5.776 0.89641 1.00000
RegionR4 0.025 5.776 0.97626 1.00000
RegionR5 -0.789 5.776 0.29729 0.63148
RegionR6 -0.025 5.776 0.96641 1.00000
RegionR7 0.251 5.776 0.72321 1.00000
RegionR8 -0.396 5.776 0.62635 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.827 5.776 0.25010 0.96639
RegenerationR2 -1.983 5.776 0.04117 0.33476
RegenerationR3 -0.439 5.776 0.63127 0.92074
RegenerationR4 -1.138 5.776 0.20799 0.65494
RegenerationR5 -1.077 5.776 0.23125 0.66477
RegenerationR6 -2.489 5.776 0.01050 0.12665
RegenerationBL -3.436 5.776 0.00118 0.02550
RegenerationTP -2.863 5.776 0.00951 0.16528


Genes with expression patterns similar to MligTC455_38513

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_38513 2198 45.79 Mlig455_017355, Mlig455_030957

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.995

6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_017355 {REF} {Length: 883} {NoTransDecoderORF} {RNA1509_15214, RNA1509_9249} {RNA1310_44691, RNA1509_15214, RNA1509_9249} {RNA1509_15214, RNA1509_9249, RNA815_20318.1}

Mlig455_030957 {REF} {Length: 881} {NoTransDecoderORF} {RNA1509_15214} {RNA1310_44691} {RNA815_20318.1}
2. MligTC455_38512 1313 27.36 Mlig455_017439

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.989

3.676 0.918 0.944 - 0.858 - 0.956 Mlig455_017439 {REF} {Length: 957} {NoTransDecoderORF} {RNA1509_25418, RNA1509_30725, RNA1509_55544} {RNA1310_48921, RNA1509_25418, RNA1509_30725, RNA1509_55544} {RNA1509_25418, RNA1509_30725, RNA1509_55544, RNA815_23196.2}
3. MligTC455_48762 230 4.8 Mlig455_023526

Neo: -

Age: -

Region-enriched R4: 3.151/0.00536
Region-enriched R3: 2.647/0.02199
Region-enriched R5: 2.161/0.03844

2.726 - - 0.969 0.863 - 0.894 Mlig455_023526 {REF} {Length: 2233} {RNA1310_25601.1} {RNA815_24861}
4. MligTC455_48763 227 4.72 Mlig455_023566

Neo: -

Age: logFC(26M/2M)=-0.692

Region-enriched R4: 3.166/0.00991

2.719 - - 0.969 0.855 - 0.895 Mlig455_023566 {REF} {Length: 2191} {RNA1310_31028} {RNA815_24861}
5. MligTC455_53528 378 7.87 Mlig455_040364

Neo: -

Age: logFC(26M/2M)=0.734

Region-enriched R4: 3.457/0.00234
Region-enriched R3: 2.972/0.00183

2.654 - - 0.872 0.801 - 0.981 Mlig455_040364 {REF} {Length: 1576} {TRANSSPLICED} {Pfam: Universal stress protein family [PF00582.28, score=97.2]} {Smed: dd_Smed_v6_985_0_1, dd_Smed_v6_985_0_1, [RH, Score=119, Expect=9e-35]} {RNA1509_7232} {RNA1310_49135, RNA1509_7232} {RNA1509_7232, RNA815_18182.1}
6. MligTC455_18707 1872 38.99 Mlig455_027577

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.006/0.00181

QRICH2 2.593 - - 0.893 - 0.735 0.965 Mlig455_027577 {REF} {Length: 5745} {Human: ENSG00000129646, QRICH2, glutamine rich 2, [Score=74.7, Expect=1e-12]} {Mouse: ENSMUSG00000070331, Qrich2, glutamine rich 2, [Score=103, Expect=1e-21]} {RNA1509_3833} {RNA1310_27824} {RNA815_7635}
7. MligTC455_18657 1027 21.4 Mlig455_057103

Neo: -

Age: -

Region-enriched R4: 2.242/0.00004
Region-enriched R3: 1.563/0.00201

TSPAN11 2.587 - - 0.955 - 0.737 0.895 Mlig455_057103 {REF} {Length: 1976} {Pfam: Tetraspanin family [PF00335.22, score=84.9]} {Human: ENSG00000110900, TSPAN11, tetraspanin 11, [Score=91.7, Expect=3e-21]} {Mouse: ENSMUSG00000030351, Tspan11, tetraspanin 11, [Score=88.2, Expect=3e-20]} {Dmel: FBgn0036769, Tsp74F, Tetraspanin 74F, [Score=78.6, Expect=6e-17]} {Celegans: WBGene00006646, tsp-20, TetraSPanin family, [RH, Score=64.3, Expect=7e-12]} {RNA1509_17216, RNA1509_35890} {RNA1310_9088, RNA1509_17216, RNA1509_35890} {RNA1509_17216, RNA1509_35890, RNA815_16895}
8. MligTC455_16515 328 6.84 Mlig455_025215

Neo: -

Age: Up-Down-Up

Region-specific R4: 3.768

Region-enriched R3: 2.309/0.00099
Region-enriched R4: 1.811/0.02291

2.54 - - 0.955 0.767 - 0.818 Mlig455_025215 {REF} {Length: 1677} {Pfam: N-formylglutamate amidohydrolase [PF05013.14, score=35.8]} {RNA1509_20433} {RNA1310_23627.3} {RNA815_15550}
9. MligTC455_16064 205 4.27 Mlig455_026327

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.743

Region-enriched R3: 2.239/0.00850

SLC39A14 1.855 - - 0.951 - - 0.904 Mlig455_026327 {REF} {Length: 2551} {Pfam: ZIP Zinc transporter [PF02535.24, score=177.4]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=187, Expect=6e-53]; ENSG00000196950, SLC39A10, solute carrier family 39 member 10, [Score=179, Expect=2e-48]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=184, Expect=4e-52]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=144, Expect=3e-37]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=160, Expect=3e-44]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=213, Expect=2e-63]} {RNA1509_16476} {RNA1310_11294, RNA1509_16476} {RNA1509_16476, RNA815_5274}
10. MligTC455_51957 427 8.9 Mlig455_001616

Neo: -

Age: logFC(26M/2M)=0.792

LCK 1.836 - - 0.975 - - 0.861 Mlig455_001616 {REF} {Length: 2834} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=195.1]; Protein kinase domain [PF00069.27, score=130.1]; Variant SH3 domain [PF14604.8, score=43.0]; SH2 domain [PF00017.26, score=42.8]; Variant SH3 domain [PF07653.19, score=36.6]; SH3 domain [PF00018.30, score=35.8]; ABC1 atypical kinase-like domain [PF03109.18, score=28.0]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=251, Expect=7e-78]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=250, Expect=5e-77]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=241, Expect=1e-73]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=255, Expect=4e-79]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=243, Expect=7e-75]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=239, Expect=4e-73]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=213, Expect=5e-64]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=304, Expect=6e-99]} {RNA1509_10615, RNA1509_47356} {RNA1310_9006.1, RNA1509_47356} {RNA1509_47356, RNA815_3005.1}
11. MligTC455_35962 331 6.9 Mlig455_022661

Neo: -

Age: -

1.811 - - 0.827 - - 0.984 Mlig455_022661 {REF} {Length: 220} {NoTransDecoderORF} {RNA1509_19906} {RNA1310_19437} {RNA815_21043}
12. MligTC455_24698 664 13.84 Mlig455_002176

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.133/0.00000
Region-enriched R4: 1.095/0.04769

1.797 - - 0.967 - - 0.830 Mlig455_002176 {REF} {Length: 1826} {TRANSSPLICED} {RNA1509_10156} {RNA1310_5607} {RNA815_1167}
13. MligTC455_28838 84 1.75 Mlig455_007557

Neo: -

Age: -

Region-enriched R4: 3.260/0.01289
Region-enriched R5: 2.662/0.02640

1.796 - - 0.968 - - 0.828 Mlig455_007557 {REF} {Length: 745} {RNA1310_66594.1} {RNA815_40011}
14. MligTC455_14589 388 8.07 Mlig455_011700

Neo: -

Age: Down-Up-Up

Region-enriched R3: 1.689/0.03987

MAP3K15 1.79 - - - 0.955 - 0.835 Mlig455_011700 {REF} {Length: 1298} {Pfam: Protein kinase domain [PF00069.27, score=167.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.1]; ABC1 atypical kinase-like domain [PF03109.18, score=24.5]; Kinase-like [PF14531.8, score=22.2]; Phosphotransferase enzyme family [PF01636.25, score=21.4]} {Human: ENSG00000180815, MAP3K15, mitogen-activated protein kinase kinase kinase 15, [Score=105, Expect=9e-25]; ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=105, Expect=7e-25]; ENSG00000142733, MAP3K6, mitogen-activated protein kinase kinase kinase 6, [Score=102, Expect=9e-24]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=104, Expect=8e-25]; ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=103, Expect=3e-24]; ENSMUSG00000031303, Map3k15, mitogen-activated protein kinase kinase kinase 15, [Score=100, Expect=3e-23]; ENSMUSG00000071369, Map3k5, mitogen-activated protein kinase kinase kinase 5, [Score=99.4, Expect=1e-22]} {Dmel: FBgn0031030, Tao, [Score=102, Expect=6e-24]} {Celegans: WBGene00022603, gck-2, Mitogen-activated protein kinase kinase kinase kinase, [Score=98.2, Expect=1e-22]} {Smed: dd_Smed_v6_5720_0_1, dd_Smed_v6_5720_0_1, [Score=102, Expect=4e-24]} {RNA1509_40003} {RNA1310_23767} {RNA815_9960}
15. MligTC455_36670 7190 149.79 Mlig455_022898

Neo: Int S/G2/M

Age: -

1.769 - - 0.965 - - 0.804 Mlig455_022898 {REF} {Length: 814} {TRANSSPLICED} {Pfam: Deltamethrin resistance [PF16020.7, score=24.4]} {RNA1509_17575, RNA1509_21523, RNA1509_29049, RNA1509_534, RNA1509_9567} {RNA1310_44846.1, RNA1509_17575, RNA1509_21523, RNA1509_29049, RNA1509_534, RNA1509_9567} {RNA1509_17575, RNA1509_21523, RNA1509_29049, RNA1509_534, RNA1509_9567, RNA815_21459}
16. MligTC455_19214 797 16.61 Mlig455_067480, Mlig455_067488

Neo: -

Age: logFC(26M/2M)=0.411

Region-enriched R4: 2.048/0.00458

HSD11B1 1.767 - - - 0.817 - 0.950

Mlig455_067480 {REF} {Length: 1095} {Pfam: short chain dehydrogenase [PF00106.27, score=63.8]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=42.8]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=83.6, Expect=1e-18]} {Mouse: ENSMUSG00000029311, Hsd17b11, hydroxysteroid (17-beta) dehydrogenase 11, [Score=59.7, Expect=2e-10]} {Dmel: FBgn0039043, CG17121, [Score=49.7, Expect=7e-07]} {RNA1509_28182} {RNA1310_27439} {RNA815_13316}

Mlig455_067488 {REF} {Length: 1390} {Pfam: short chain dehydrogenase [PF00106.27, score=128.2]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=83.0]; KR domain [PF08659.12, score=25.0]; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [PF02882.21, score=18.0]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=158, Expect=4e-46]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=151, Expect=1e-43]} {Dmel: FBgn0051548, CG31548, [Score=80.9, Expect=2e-17]} {Celegans: WBGene00019885, R05D8.7, [Score=80.1, Expect=3e-17]} {Smed: dd_Smed_v6_3167_0_1, dd_Smed_v6_3167_0_1, [Score=71.6, Expect=2e-14]} {RNA1509_28182, RNA1509_29712, RNA1509_41682} {RNA1310_27439, RNA1509_28182, RNA1509_29712, RNA1509_41682} {RNA1509_28182, RNA1509_29712, RNA1509_41682, RNA815_13316}
17. MligTC455_36081 1387 28.89 Mlig455_040332

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.740

Region-enriched R3: 3.050/0.00000
Region-enriched R4: 2.803/0.00000
Region-enriched R5: 2.050/0.00000

1.76 - - - - 0.806 0.954 Mlig455_040332 {REF} {Length: 2953} {Pfam: Transforming growth factor beta like domain [PF00019.22, score=44.8]} {RNA1509_5434} {RNA1310_5336} {RNA815_1739.1}
18. MligTC455_48070 1559 32.49 Mlig455_019661

Neo: -

Age: logFC(26M/2M)=-0.328

Region-enriched R3: 1.615/0.01457

HSD11B1 1.757 - - - 0.796 - 0.961 Mlig455_019661 {REF} {Length: 1828} {Pfam: short chain dehydrogenase [PF00106.27, score=125.5]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=75.3]; KR domain [PF08659.12, score=27.1]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=157, Expect=2e-45]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=154, Expect=1e-44]} {Dmel: FBgn0027583, CG7601, [Score=82.0, Expect=1e-17]} {Celegans: WBGene00014093, ZK829.1, [Score=74.3, Expect=4e-15]} {Smed: dd_Smed_v6_3167_0_1, dd_Smed_v6_3167_0_1, [Score=62.8, Expect=2e-11]} {RNA1509_11335, RNA1509_15148} {RNA1310_26648, RNA1509_11335, RNA1509_15148} {RNA1509_11335, RNA1509_15148, RNA815_11342}
19. MligTC455_39889 2060 42.92 Mlig455_033747

Neo: -

Age: -

GDPD1 1.742 - - - 0.773 - 0.969 Mlig455_033747 {REF} {Length: 1632} {Pfam: Glycerophosphoryl diester phosphodiesterase family [PF03009.19, score=130.1]} {Human: ENSG00000153982, GDPD1, glycerophosphodiester phosphodiesterase domain containing 1, [Score=57.4, Expect=4e-09]} {Mouse: ENSMUSG00000061666, Gdpd1, glycerophosphodiester phosphodiesterase domain containing 1, [Score=55.1, Expect=4e-08]} {Celegans: WBGene00021497, Y40C5A.4, [RH, Score=53.9, Expect=5e-08]} {RNA1509_4963, RNA1509_55034, RNA1509_9150} {RNA1310_11037, RNA1509_4963, RNA1509_55034, RNA1509_9150} {RNA1509_4963, RNA1509_55034, RNA1509_9150, RNA815_4734}
20. MligTC455_43763 1548 32.26 Mlig455_009134

Neo: -

Age: -

ETFDH 1.726 - - 0.951 - - 0.775 Mlig455_009134 {REF} {Length: 3198} {TRANSSPLICED} {Pfam: Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S [PF05187.15, score=158.2]; FAD dependent oxidoreductase [PF01266.26, score=34.3]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=32.5]; FAD binding domain [PF00890.26, score=32.1]; Thi4 family [PF01946.19, score=31.3]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=27.3]; FAD-NAD(P)-binding [PF13454.8, score=23.5]; FAD binding domain [PF01494.21, score=19.2]; Alanine dehydrogenase/PNT, C-terminal domain [PF01262.23, score=18.7]; HI0933-like protein [PF03486.16, score=18.2]} {Human: ENSG00000171503, ETFDH, electron transfer flavoprotein dehydrogenase, [RH, Score=814, Expect=0.0]} {Mouse: ENSMUSG00000027809, Etfdh, electron transferring flavoprotein, dehydrogenase, [RH, Score=829, Expect=0.0]} {Dmel: FBgn0033465, Etf-QO, Electron transfer flavoprotein-ubiquinone oxidoreductase, [RH, Score=753, Expect=0.0]} {Celegans: WBGene00002855, let-721, Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial, [RH, Score=745, Expect=0.0]} {Smed: dd_Smed_v6_3785_0_1, dd_Smed_v6_3785_0_1, [RH, Score=872, Expect=0.0]} {RNA1509_2025, RNA1509_6739} {RNA1310_8787, RNA1509_2025, RNA1509_6739} {RNA1509_2025, RNA1509_6739, RNA815_3614}
21. MligTC455_18225 657 13.69 Mlig455_034956

Neo: -

Age: logFC(26M/2M)=0.287

1.71 - - 0.952 - - 0.758 Mlig455_034956 {REF} {Length: 2635} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=45.3]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=40.0]} {Dmel: FBgn0037518, CG2641, [Score=52.4, Expect=4e-07]} {Celegans: WBGene00012464, arrd-7, ARRestin Domain protein, [Score=54.7, Expect=5e-08]} {RNA1509_22116} {RNA1310_8444.1, RNA1509_22116} {RNA1509_22116, RNA815_2910}
22. MligTC455_41503 3372 70.25 Mlig455_015421

Neo: -

Age: -

Region-enriched R3: 1.663/0.00123

1.672 - - - 0.708 - 0.964 Mlig455_015421 {REF} {Length: 3377} {Pfam: Fasciclin domain [PF02469.24, score=41.0]} {Dmel: FBgn0032638, SPH93, Serine protease homolog 93, [Score=61.6, Expect=2e-09]} {RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1310_8987, RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1509_26815, RNA1509_27548, RNA1509_56488, RNA815_3084.1}
23. MligTC455_44530 352 7.33 Mlig455_038035

Neo: -

Age: Down-Up-Up

Region-enriched R3: 1.753/0.00110
Region-enriched R4: 1.598/0.01280
Region-enriched R5: 1.140/0.02561

1.671 - - 0.711 - - 0.960 Mlig455_038035 {REF} {Length: 1762} {Pfam: Universal stress protein family [PF00582.28, score=87.1]} {Smed: dd_Smed_v6_3388_0_1, dd_Smed_v6_3388_0_1, [Score=82.0, Expect=3e-20]} {RNA1509_59467} {RNA1310_35905, RNA1509_59467} {RNA1509_59467, RNA815_18113}
24. MligTC455_53923 413 8.6 Mlig455_031505

Neo: -

Age: -

Region-enriched R3: 2.700/0.00511

MGAM 1.669 - - - 0.702 - 0.967 Mlig455_031505 {REF} {Length: 3805} {Pfam: Glycosyl hydrolases family 31 [PF01055.28, score=338.5]} {Human: ENSG00000282607, MGAM, maltase-glucoamylase, [Score=363, Expect=4e-110]; ENSG00000257335, MGAM, maltase-glucoamylase, [Score=363, Expect=4e-110]; ENSG00000090402, SI, sucrase-isomaltase, [Score=359, Expect=6e-109]; ENSG00000278563, MGAM2, maltase-glucoamylase 2 (putative), [Score=347, Expect=9e-105]; ENSG00000257743, MGAM2, maltase-glucoamylase 2 (putative), [Score=347, Expect=9e-105]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [Score=361, Expect=6e-112]; ENSMUSG00000027790, Sis, sucrase isomaltase (alpha-glucosidase), [Score=353, Expect=4e-107]} {Dmel: FBgn0027588, GCS2alpha, Glucosidase 2 alpha subunit, [Score=150, Expect=6e-38]} {Celegans: WBGene00019895, aagr-2, Acid Alpha Glucosidase Relate, [Score=364, Expect=3e-115]} {Smed: dd_Smed_v6_4668_0_1, dd_Smed_v6_4668_0_1, [Score=333, Expect=6e-104]} {RNA1509_3169} {RNA1310_1135} {RNA815_4014}
25. MligTC455_43764 562 11.71 Mlig455_009581

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.455

ETFDH 1.665 - - 0.951 - - 0.714 Mlig455_009581 {REF} {Length: 2120} {Human: ENSG00000171503, ETFDH, electron transfer flavoprotein dehydrogenase, [Score=169, Expect=2e-49]} {Mouse: ENSMUSG00000027809, Etfdh, electron transferring flavoprotein, dehydrogenase, [Score=171, Expect=1e-50]} {Dmel: FBgn0033465, Etf-QO, Electron transfer flavoprotein-ubiquinone oxidoreductase, [Score=150, Expect=8e-43]} {Celegans: WBGene00002855, let-721, Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial, [Score=162, Expect=3e-47]} {Smed: dd_Smed_v6_3785_0_1, dd_Smed_v6_3785_0_1, [Score=184, Expect=9e-56]} {RNA1509_2025} {RNA1310_8787} {RNA815_3614}
26. MligTC455_35963 222 4.63 Mlig455_022679

Neo: -

Age: logFC(26M/2M)=0.351

Region-enriched R3: 1.680/0.02750

0.984 - - - - - 0.984 Mlig455_022679 {REF} {Length: 3869} {TRANSSPLICED} {Pfam: Glycosyl hydrolase family 63 C-terminal domain [PF03200.18, score=26.0]; Protein of unknown function (DUF4232) [PF14016.8, score=20.8]} {RNA1509_18909, RNA1509_19906, RNA1509_9146} {RNA1310_4028.1, RNA1509_18909, RNA1509_19906, RNA1509_9146} {RNA1509_18909, RNA1509_19906, RNA1509_9146, RNA815_1420}
27. MligTC455_21807 799 16.65 Mlig455_007459

Neo: Neoblast, stringent

Age: -

Region-enriched R4: 2.408/0.00022

CNFN 0.98 - - 0.980 - - - Mlig455_007459 {REF} {Length: 4701} {Pfam: PLAC8 family [PF04749.19, score=53.4]} {Human: ENSG00000105427, CNFN, cornifelin, [Score=53.5, Expect=2e-08]} {Mouse: ENSMUSG00000063651, Cnfn, cornifelin, [Score=56.6, Expect=1e-09]} {Smed: dd_Smed_v6_865_0_1, dd_Smed_v6_865_0_1, [Score=86.3, Expect=4e-20]} {RNA1509_19934} {RNA1310_30308.1} {RNA815_18628.1}
28. MligTC455_19197 67 1.4 Mlig455_007034

Neo: -

Age: -

Region-enriched R4: 3.641/0.00186

0.978 - - 0.978 - - - Mlig455_007034 {REF} {Length: 1592} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_59235} {RNA1310_17424.2} {RNA815_5050}
29. MligTC455_22151 1286 26.78 Mlig455_054961

Neo: -

Age: Down-Up-Down

Region-enriched R4: 2.174/0.00000
Region-enriched R3: 1.898/0.00000
Region-enriched R5: 1.123/0.00549

XDH 0.973 - - - - - 0.973 Mlig455_054961 {REF} {Length: 8931} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=746.5]; [2Fe-2S] binding domain [PF01799.22, score=187.9]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=151.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=115.0]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=110.3]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=28.4]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=490, Expect=1e-144]; ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=472, Expect=2e-138]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=496, Expect=5e-147]; ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=472, Expect=7e-139]} {Dmel: FBgn0038349, AOX3, Aldehyde oxidase 3, [RH, Score=658, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=501, Expect=1e-148]} {RNA1509_48253} {RNA1310_3150.1} {RNA815_224.3}
30. MligTC455_15896 224 4.67 Mlig455_000871

Neo: -

Age: -

Region-enriched R3: 3.079/0.00082

SLC22A5 0.971 - - - - - 0.971 Mlig455_000871 {REF} {Length: 3053} {Pfam: Sugar (and other) transporter [PF00083.26, score=128.9]; Major Facilitator Superfamily [PF07690.18, score=82.2]} {Human: ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=191, Expect=3e-53]; ENSG00000172940, SLC22A13, solute carrier family 22 member 13, [Score=187, Expect=6e-52]} {Mouse: ENSMUSG00000023828, Slc22a3, solute carrier family 22 (organic cation transporter), member 3, [Score=188, Expect=2e-52]; ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=187, Expect=5e-52]; ENSMUSG00000018900, Slc22a5, solute carrier family 22 (organic cation transporter), member 5, [Score=182, Expect=3e-50]} {Dmel: FBgn0086365, Orct2, Organic cation transporter 2, [Score=238, Expect=6e-71]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=183, Expect=6e-51]} {Smed: dd_Smed_v6_10903_0_1, dd_Smed_v6_10903_0_1, [RH, Score=244, Expect=2e-74]} {RNA1509_34392, RNA1509_36858, RNA1509_7569} {RNA1310_6516, RNA1509_34392, RNA1509_36858, RNA1509_7569} {RNA1509_34392, RNA1509_36858, RNA1509_7569, RNA815_4307.1}
31. MligTC455_23758 446 9.29 Mlig455_015280

Neo: S/G2/M, no gonads

Age: -

Region-specific R4: 4.011

Region-enriched R4: 2.914/0.00014

MOCS3 0.971 - - 0.971 - - - Mlig455_015280 {REF} {Length: 5270} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=233.6]; ThiF family [PF00899.23, score=202.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=117.5]; Rhodanese-like domain [PF00581.22, score=28.3]; Kinase-like [PF14531.8, score=18.6]} {Human: ENSG00000124217, MOCS3, molybdenum cofactor synthesis 3, [RH, Score=334, Expect=5e-104]} {Mouse: ENSMUSG00000074576, Mocs3, molybdenum cofactor synthesis 3, [RH, Score=342, Expect=5e-107]} {Dmel: FBgn0032054, Uba4, Ubiquitin activating enzyme 4, [RH, Score=357, Expect=8e-113]} {Celegans: WBGene00018357, moc-3, Adenylyltransferase and sulfurtransferase MOCS3 Molybdopterin-synthase adenylyltransferase Molybdopterin-synthase sulfurtransferase, [RH, Score=316, Expect=3e-98]} {Smed: dd_Smed_v6_5985_0_1, dd_Smed_v6_5985_0_1, [RH, Score=338, Expect=2e-106]} {RNA1509_4475} {RNA1310_10755} {RNA815_4321.1}
32. MligTC455_36082 1063 22.14 Mlig455_040337

Neo: -

Age: logFC(26M/2M)=-0.499

Region-enriched R4: 3.060/0.00000
Region-enriched R3: 2.482/0.00000
Region-enriched R5: 2.159/0.00000

0.971 - - - - - 0.971 Mlig455_040337 {REF} {Length: 3101} {Pfam: Transforming growth factor beta like domain [PF00019.22, score=47.9]} {RNA1509_22478, RNA1509_5434} {RNA1310_5336, RNA1509_22478} {RNA1509_22478, RNA815_1739.1}
33. MligTC455_37238 1196 24.92 Mlig455_049614

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.981

Region-enriched R3: 1.482/0.00582

PANK4 0.971 - - - - - 0.971 Mlig455_049614 {REF} {Length: 1474} {Pfam: Fumble [PF03630.16, score=119.6]} {Human: ENSG00000157881, PANK4, pantothenate kinase 4, [Score=104, Expect=9e-24]; ENSG00000273494, PANK4, pantothenate kinase 4, [Score=104, Expect=9e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=95.9, Expect=4e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=65.1, Expect=3e-11]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=173, Expect=7e-51]} {RNA1509_8444} {RNA1310_20224, RNA1509_8444} {RNA1509_8444, RNA815_7673}
34. MligTC455_53857 179 3.72 Mlig455_001791

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.706

Region-enriched R4: 2.741/0.04948
Region-enriched R5: 2.524/0.03099

0.968 - - 0.968 - - - Mlig455_001791 {REF} {Length: 2180} {RNA1509_13138} {RNA1310_39332} {RNA815_45779}
35. MligTC455_52159 5039 104.98 Mlig455_022930

Neo: -

Age: logFC(26M/2M)=-1.171

Region-enriched R3: 2.011/0.00288

CALM3 0.966 - - - - - 0.966 Mlig455_022930 {REF} {Length: 1221} {Pfam: EF hand [PF00036.34, score=110.8]; EF-hand domain pair [PF13499.8, score=103.6]; EF-hand domain pair [PF13833.8, score=88.4]; EF hand [PF13202.8, score=87.3]; EF-hand domain [PF13405.8, score=76.4]; EF-hand domain [PF14658.8, score=35.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=34.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=32.0]; Dockerin type I domain [PF00404.20, score=27.9]; EF-hand domain [PF08976.13, score=20.6]; GYF domain 2 [PF14237.8, score=19.3]} {Human: ENSG00000160014, CALM3, calmodulin 3, [Score=133, Expect=4e-40]; ENSG00000198668, CALM1, calmodulin 1, [Score=133, Expect=4e-40]; ENSG00000143933, CALM2, calmodulin 2, [Score=133, Expect=4e-40]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=133, Expect=3e-40]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=133, Expect=3e-40]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=133, Expect=3e-40]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=129, Expect=6e-39]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=129, Expect=8e-39]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=129, Expect=6e-39]} {RNA1509_24239, RNA1509_33140, RNA1509_4775, RNA1509_8044} {RNA1310_32140.1, RNA1509_24239, RNA1509_33140, RNA1509_4775, RNA1509_8044} {RNA1509_24239, RNA1509_33140, RNA1509_4775, RNA1509_8044, RNA815_3424.1}
36. MligTC455_26412 639 13.31 Mlig455_048980, Mlig455_067777

Neo: Germline

Age: Up-Down-Down

Region-specific R4: 6.291

Region-enriched R4: 3.563/0.00042
Region-enriched R3: 2.335/0.04900

SUSD2 0.963 - - 0.963 - - -

Mlig455_048980 {REF} {Length: 2836} {Pfam: AMOP domain [PF03782.19, score=46.0]} {Human: ENSG00000099994, SUSD2, sushi domain containing 2, [Score=52.4, Expect=4e-06]} {Mouse: ENSMUSG00000006342, Susd2, sushi domain containing 2, [Score=54.3, Expect=6e-07]} {RNA1509_14135} {RNA1310_6868} {RNA815_3203.1}

Mlig455_067777 {REF} {Length: 2823} {Pfam: AMOP domain [PF03782.19, score=46.3]} {Human: ENSG00000099994, SUSD2, sushi domain containing 2, [Score=52.8, Expect=2e-06]} {Mouse: ENSMUSG00000006342, Susd2, sushi domain containing 2, [Score=53.9, Expect=6e-07]} {RNA1509_14135} {RNA1310_6868} {RNA815_3203.1}
37. MligTC455_27756 2766 57.63 Mlig455_036299, Mlig455_036313

Neo: -

Age: logFC(26M/2M)=0.266

Region-enriched R3: 1.773/0.00001
Region-enriched R4: 1.368/0.00784

AF241726.2, TSPAN7 0.963 - - - - - 0.963

Mlig455_036299 {REF} {Length: 1664} {Pfam: Tetraspanin family [PF00335.22, score=86.9]} {Human: ENSG00000250349, AF241726.2, novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein, [Score=63.2, Expect=7e-11]; ENSG00000156298, TSPAN7, tetraspanin 7, [Score=62.8, Expect=8e-11]} {Mouse: ENSMUSG00000058254, Tspan7, tetraspanin 7, [Score=61.6, Expect=1e-10]; ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=59.3, Expect=7e-10]} {Celegans: WBGene00023491, tsp-21, Tetraspanin, [Score=50.4, Expect=5e-07]} {Smed: dd_Smed_v6_854_1_1, dd_Smed_v6_854_1_1, [Score=109, Expect=3e-28]} {RNA1509_20407} {RNA1310_5241, RNA1509_20407} {RNA1509_20407, RNA815_7978}

Mlig455_036313 {REF} {Length: 3246} {Pfam: Tetraspanin family [PF00335.22, score=139.9]} {Human: ENSG00000156298, TSPAN7, tetraspanin 7, [Score=62.4, Expect=6e-10]; ENSG00000250349, AF241726.2, novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein, [Score=60.5, Expect=3e-09]} {Mouse: ENSMUSG00000058254, Tspan7, tetraspanin 7, [Score=61.6, Expect=6e-10]} {Smed: dd_Smed_v6_854_1_1, dd_Smed_v6_854_1_1, [Score=107, Expect=9e-26]} {RNA1509_20407} {RNA1310_5241} {RNA815_7978}
38. MligTC455_52158 2513 52.35 Mlig455_022825

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.661/0.02974
Region-enriched R3: 1.635/0.02881
Region-enriched R5: 1.518/0.01597

CALM3 0.963 - - - - - 0.963 Mlig455_022825 {REF} {Length: 1438} {Pfam: EF hand [PF00036.34, score=111.3]; EF-hand domain pair [PF13499.8, score=103.6]; EF-hand domain pair [PF13833.8, score=88.5]; EF hand [PF13202.8, score=87.3]; EF-hand domain [PF13405.8, score=76.4]; EF-hand domain [PF14658.8, score=35.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=34.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=32.0]; Dockerin type I domain [PF00404.20, score=27.9]; EF-hand domain [PF08976.13, score=20.6]; GYF domain 2 [PF14237.8, score=19.3]} {Human: ENSG00000160014, CALM3, calmodulin 3, [Score=131, Expect=1e-39]; ENSG00000198668, CALM1, calmodulin 1, [Score=131, Expect=1e-39]; ENSG00000143933, CALM2, calmodulin 2, [Score=131, Expect=1e-39]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=131, Expect=1e-39]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=131, Expect=1e-39]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=131, Expect=1e-39]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=128, Expect=2e-38]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=128, Expect=2e-38]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=128, Expect=1e-38]} {RNA1509_11596, RNA1509_31225, RNA1509_4775, RNA1509_6227} {RNA1310_32140.1, RNA1509_11596, RNA1509_31225, RNA1509_6227} {RNA1509_11596, RNA1509_31225, RNA1509_6227, RNA815_3424.1}
39. MligTC455_09328 39 0.8 Mlig455_032045

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.716

0.962 - - - - - 0.962 Mlig455_032045 {REF} {Length: 2583} {Pfam: Domain of unknown function (DUF4010) [PF13194.8, score=20.4]} {RNA1310_46777} {RNA815_42352}
40. MligTC455_17913 888 18.51 Mlig455_033627, Mlig455_033723

Neo: -

Age: logFC(26M/2M)=0.569

Region-enriched R3: 2.898/0.00022
Region-enriched R4: 2.202/0.04383
Region-enriched R5: 2.128/0.00645

PRR5L 0.962 - - - - - 0.962

Mlig455_033627 {REF} {Length: 1798} {Pfam: HbrB-like [PF08539.13, score=22.1]} {Human: ENSG00000135362, PRR5L, proline rich 5 like, [RH, Score=73.9, Expect=6e-14]; ENSG00000186654, PRR5, proline rich 5, [RH, Score=72.4, Expect=2e-13]} {Mouse: ENSMUSG00000032841, Prr5l, proline rich 5 like, [RH, Score=73.6, Expect=6e-14]; ENSMUSG00000036106, Prr5, proline rich 5 (renal), [RH, Score=73.6, Expect=7e-14]} {RNA1509_12705} {RNA1310_18214, RNA1509_12705} {RNA1509_12705, RNA815_7990}

Mlig455_033723 {REF} {Length: 1737} {Pfam: HbrB-like [PF08539.13, score=22.1]} {Human: ENSG00000135362, PRR5L, proline rich 5 like, [RH, Score=73.9, Expect=7e-14]; ENSG00000186654, PRR5, proline rich 5, [RH, Score=72.4, Expect=2e-13]} {Mouse: ENSMUSG00000036106, Prr5, proline rich 5 (renal), [RH, Score=73.6, Expect=7e-14]; ENSMUSG00000032841, Prr5l, proline rich 5 like, [RH, Score=73.6, Expect=7e-14]} {RNA1509_12705} {RNA1310_18214} {RNA815_7990}
41. MligTC455_18366 547 11.39 Mlig455_026325

Neo: -

Age: Down-Down-Up

Region-enriched R4: 3.044/0.02719
Region-enriched R3: 2.953/0.02551

IFI30 0.962 - - - - - 0.962 Mlig455_026325 {REF} {Length: 1133} {Pfam: Gamma interferon inducible lysosomal thiol reductase (GILT) [PF03227.18, score=101.0]} {Human: ENSG00000216490, IFI30, IFI30, lysosomal thiol reductase, [RH, Score=143, Expect=1e-41]} {Mouse: ENSMUSG00000110777, Ifi30, interferon gamma inducible protein 30, [RH, Score=118, Expect=4e-32]} {Dmel: FBgn0038149, GILT1, Gamma-interferon-inducible lysosomal thiol reductase 1, [Score=95.5, Expect=1e-23]} {Celegans: WBGene00009514, F37H8.5, GILT-like protein F37H8.5, [Score=100, Expect=3e-25]} {Smed: dd_Smed_v6_2024_0_1, dd_Smed_v6_2024_0_1, [Score=104, Expect=8e-28]} {RNA1509_51694} {RNA1310_32351.1} {RNA815_17592}
42. MligTC455_18651 2559 53.32 Mlig455_067661

Neo: -

Age: -

Region-enriched R3: 1.583/0.04334

0.962 - - - - - 0.962 Mlig455_067661 {REF} {Length: 616} {RNA1509_2812} {RNA1310_3353.1, RNA1509_2812} {RNA1509_2812, RNA815_7653}
43. MligTC455_21905 681 14.18 Mlig455_016692, Mlig455_062345

Neo: Germline

Age: logFC(26M/2M)=0.410

Region-enriched R4: 2.760/0.00010

0.961 - - 0.961 - - -

Mlig455_016692 {REF} {Length: 3207} {RNA1509_11497} {RNA1310_2097} {RNA815_6620}

Mlig455_062345 {REF} {Length: 877} {NoTransDecoderORF} {RNA1509_17998} {RNA1310_44069} {RNA815_10763.1}
44. MligTC455_36792 641 13.36 Mlig455_040816, Mlig455_040917, Mlig455_049184

Neo: Germline

Age: Up-Down-Down, logFC(26M/2M)=-0.297

Region-specific R4: 6.507

Region-enriched R4: 5.509/0.00000

ADAM17 0.961 - - 0.961 - - -

Mlig455_040816 {REF} {Length: 3099} {Pfam: Metallo-peptidase family M12 [PF13688.8, score=77.4]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=62.9]; Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=37.9]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=21.6]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=21.2]; Reprolysin family propeptide [PF01562.21, score=20.4]} {Human: ENSG00000151694, ADAM17, ADAM metallopeptidase domain 17, [Score=260, Expect=3e-75]} {Mouse: ENSMUSG00000052593, Adam17, a disintegrin and metallopeptidase domain 17, [Score=257, Expect=4e-74]} {Dmel: FBgn0039734, Tace, [Score=270, Expect=8e-80]} {Celegans: WBGene00000075, adm-4, ADAM (Disintegrin plus metalloprotease) family, [Score=183, Expect=6e-49]} {Smed: dd_Smed_v6_10958_0_1, dd_Smed_v6_10958_0_1, [Score=55.8, Expect=5e-08]} {RNA1509_17096, RNA1509_45736} {RNA1310_6968, RNA1509_17096, RNA1509_45736} {RNA1509_17096, RNA1509_45736, RNA815_7112.1}

Mlig455_040917 {REF} {Length: 3504} {Pfam: Metallo-peptidase family M12 [PF13688.8, score=77.1]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=62.7]; Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=37.6]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=21.4]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=20.7]; Reprolysin family propeptide [PF01562.21, score=20.2]} {Human: ENSG00000151694, ADAM17, ADAM metallopeptidase domain 17, [Score=266, Expect=1e-76]} {Mouse: ENSMUSG00000052593, Adam17, a disintegrin and metallopeptidase domain 17, [Score=258, Expect=3e-74]} {Dmel: FBgn0039734, Tace, [Score=271, Expect=6e-80]} {Celegans: WBGene00000075, adm-4, ADAM (Disintegrin plus metalloprotease) family, [Score=185, Expect=3e-49]} {Smed: dd_Smed_v6_10958_0_1, dd_Smed_v6_10958_0_1, [Score=56.2, Expect=5e-08]} {RNA1509_17096} {RNA1310_6968} {RNA815_7112.1}

Mlig455_049184 {REF} {Length: 2606} {Pfam: Metallo-peptidase family M12 [PF13688.8, score=77.3]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=62.8]; Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=30.6]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=21.6]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=21.3]} {Human: ENSG00000151694, ADAM17, ADAM metallopeptidase domain 17, [Score=217, Expect=8e-60]} {Mouse: ENSMUSG00000052593, Adam17, a disintegrin and metallopeptidase domain 17, [Score=211, Expect=7e-58]} {Dmel: FBgn0039734, Tace, [Score=223, Expect=9e-63]} {Celegans: WBGene00000075, adm-4, ADAM (Disintegrin plus metalloprotease) family, [Score=137, Expect=1e-33]} {RNA1509_45736} {RNA1310_6968} {RNA815_7112.1}
45. MligTC455_48796 3932 81.93 Mlig455_010032, Mlig455_063287

Neo: -

Age: -

Region-enriched R3: 1.371/0.00023

0.961 - - - - - 0.961

Mlig455_010032 {REF} {Length: 3305} {TRANSSPLICED} {Dmel: FBgn0051195, CG31195, [RH, Score=445, Expect=3e-143]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [RH, Score=727, Expect=0.0]} {RNA1509_1610, RNA1509_26475} {RNA1310_2842, RNA1509_1610, RNA1509_26475} {RNA1509_1610, RNA1509_26475, RNA815_1220.1}

Mlig455_063287 {REF} {Length: 3306} {TRANSSPLICED} {Dmel: FBgn0051195, CG31195, [RH, Score=445, Expect=4e-143]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_1610} {RNA1310_2842} {RNA815_1220.1}
46. MligTC455_08915 221 4.59 Mlig455_022738

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.442

Region-enriched R5: 2.593/0.00089

0.96 - - 0.960 - - - Mlig455_022738 {REF} {Length: 2881} {Pfam: Innexin [PF00876.20, score=285.0]} {Dmel: FBgn0265274, Inx3, Innexin 3, [Score=93.2, Expect=2e-20]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=188, Expect=1e-54]} {Smed: dd_Smed_v6_692_0_1, dd_Smed_v6_692_0_1, [Score=310, Expect=9e-102]} {RNA1509_35063, RNA1509_50192} {RNA1310_11561.1, RNA1509_35063, RNA1509_50192} {RNA1509_35063, RNA1509_50192, RNA815_7858}
47. MligTC455_11965 97 2.02 Mlig455_014571, Mlig455_070256

Neo: -

Age: -

Region-enriched R5: 2.636/0.01196

0.959 - - - - - 0.959

Mlig455_014571 {REF} {Length: 457} {NoTransDecoderORF} {RNA1509_52350} {RNA1310_144049} {RNA815_61317}

Mlig455_070256 {REF} {Length: 296} {NoTransDecoderORF} {RNA1310_61832} {RNA815_61317}
48. MligTC455_19239 304 6.34 Mlig455_010496, Mlig455_061882

Neo: Germline

Age: -

Region-specific R4: 4.751

Region-enriched R4: 4.107/0.00000

ZDHHC14 0.959 - - 0.959 - - -

Mlig455_010496 {REF} {Length: 1785} {Pfam: DHHC palmitoyltransferase [PF01529.22, score=117.8]} {Human: ENSG00000175048, ZDHHC14, zinc finger DHHC-type containing 14, [Score=144, Expect=4e-38]; ENSG00000188706, ZDHHC9, zinc finger DHHC-type containing 9, [Score=142, Expect=7e-38]} {Mouse: ENSMUSG00000034265, Zdhhc14, zinc finger, DHHC domain containing 14, [Score=146, Expect=7e-39]; ENSMUSG00000036985, Zdhhc9, zinc finger, DHHC domain containing 9, [Score=142, Expect=5e-38]} {Dmel: FBgn0260941, app, approximated, [Score=148, Expect=2e-40]} {Celegans: WBGene00012948, dhhc-2, Palmitoyltransferase, [Score=115, Expect=3e-28]} {Smed: dd_Smed_v6_9975_0_1, dd_Smed_v6_9975_0_1, [Score=131, Expect=3e-34]} {RNA1509_28960} {RNA1310_14626} {RNA815_18781}

Mlig455_061882 {REF} {Length: 1890} {TRANSSPLICED} {Pfam: DHHC palmitoyltransferase [PF01529.22, score=117.8]} {Human: ENSG00000175048, ZDHHC14, zinc finger DHHC-type containing 14, [Score=143, Expect=2e-37]; ENSG00000188706, ZDHHC9, zinc finger DHHC-type containing 9, [Score=140, Expect=3e-37]} {Mouse: ENSMUSG00000034265, Zdhhc14, zinc finger, DHHC domain containing 14, [Score=145, Expect=3e-38]; ENSMUSG00000036985, Zdhhc9, zinc finger, DHHC domain containing 9, [Score=140, Expect=2e-37]} {Dmel: FBgn0260941, app, approximated, [Score=146, Expect=1e-39]} {Celegans: WBGene00012948, dhhc-2, Palmitoyltransferase, [Score=115, Expect=3e-28]} {Smed: dd_Smed_v6_9975_0_1, dd_Smed_v6_9975_0_1, [Score=132, Expect=2e-34]} {RNA1509_28960} {RNA1310_14626, RNA1509_28960} {RNA1509_28960, RNA815_18781}
49. MligTC455_48498 1066 22.21 Mlig455_007871

Neo: -

Age: logFC(26M/2M)=0.286

Region-enriched R3: 1.717/0.03337

MICU3 0.959 - - - - - 0.959 Mlig455_007871 {REF} {Length: 2576} {Pfam: EF-hand domain pair [PF13499.8, score=34.5]; EF-hand domain [PF13405.8, score=34.4]; EF-hand domain pair [PF13833.8, score=32.0]; EF hand [PF00036.34, score=30.6]; EF hand [PF13202.8, score=22.8]} {Human: ENSG00000155970, MICU3, mitochondrial calcium uptake family member 3, [Score=260, Expect=1e-82]} {Mouse: ENSMUSG00000021973, Micu2, mitochondrial calcium uptake 2, [Score=216, Expect=3e-65]; ENSMUSG00000039478, Micu3, mitochondrial calcium uptake family, member 3, [Score=214, Expect=2e-63]} {Dmel: FBgn0038735, CG4662, [Score=282, Expect=3e-90]} {Celegans: WBGene00008345, C56A3.6, [RH, Score=239, Expect=1e-74]} {Smed: dd_Smed_v6_5430_0_1, dd_Smed_v6_5430_0_1, [Score=204, Expect=9e-61]} {RNA1509_14710, RNA1509_26156} {RNA1310_3702, RNA1509_14710, RNA1509_26156} {RNA1509_14710, RNA1509_26156, RNA815_171.2}
50. MligTC455_12568 248 5.16 Mlig455_004338

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.930/0.00096

0.957 - - - - - 0.957 Mlig455_004338 {REF} {Length: 1045} {RNA1509_26863} {RNA1310_9636.1, RNA1509_26863} {RNA1509_26863, RNA815_47943}
51. MligTC455_15227 8 0.16 Mlig455_010570

Neo: -

Age: -

0.956 - - - - - 0.956 Mlig455_010570 {REF} {Length: 1443} {RNA1509_34628} {RNA1310_104307} {RNA815_3400}
52. MligTC455_22826 607 12.65 Mlig455_006871

Neo: -

Age: -

ATG4C 0.956 - - 0.956 - - - Mlig455_006871 {REF} {Length: 5184} {TRANSSPLICED} {Pfam: Peptidase family C54 [PF03416.21, score=188.3]; Ribosomal protein L6 [PF00347.25, score=41.0]} {Human: ENSG00000125703, ATG4C, autophagy related 4C cysteine peptidase, [Score=142, Expect=2e-36]} {Mouse: ENSMUSG00000028550, Atg4c, autophagy related 4C, cysteine peptidase, [Score=137, Expect=1e-34]; ENSMUSG00000002820, Atg4d, autophagy related 4D, cysteine peptidase, [Score=137, Expect=1e-34]} {Dmel: FBgn0038325, Atg4b, Autophagy-related 4b, [Score=134, Expect=9e-33]} {Celegans: WBGene00013595, atg-4.1, Cysteine protease, [Score=127, Expect=1e-31]} {Smed: dd_Smed_v6_10824_0_1, dd_Smed_v6_10824_0_1, [RH, Score=162, Expect=1e-43]} {RNA1509_29780} {RNA1310_15687.1} {RNA815_37674}
53. MligTC455_27825 356 7.41 Mlig455_007119

Neo: Neoblast, stringent

Age: Up-Down-Down

Region-enriched R4: 1.443/0.04722

SMC4 0.956 - - 0.956 - - - Mlig455_007119 {REF} {Length: 5158} {TRANSSPLICED} {Pfam: RecF/RecN/SMC N terminal domain [PF02463.21, score=134.9]; SMC proteins Flexible Hinge Domain [PF06470.15, score=85.9]; AAA ATPase domain [PF13175.8, score=32.1]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=27.9]; AAA domain [PF13476.8, score=22.9]; P-loop containing region of AAA domain [PF13555.8, score=22.6]} {Human: ENSG00000113810, SMC4, structural maintenance of chromosomes 4, [RH, Score=589, Expect=0.0]} {Mouse: ENSMUSG00000034349, Smc4, structural maintenance of chromosomes 4, [Score=599, Expect=0.0]} {Dmel: FBgn0015391, glu, gluon, [RH, Score=515, Expect=2e-164]} {Celegans: WBGene00004874, smc-4, Structural maintenance of chromosomes protein 4, [RH, Score=329, Expect=8e-96]} {Smed: dd_Smed_v6_5865_0_4, dd_Smed_v6_5865_0_4, [RH, Score=520, Expect=2e-167]} {RNA1509_3181} {RNA1310_1138.1} {RNA815_2120}
54. MligTC455_38075 513 10.69 Mlig455_037147

Neo: -

Age: Down-Down-Up

0.956 - - - - - 0.956 Mlig455_037147 {REF} {Length: 3140} {Pfam: Zona pellucida-like domain [PF00100.25, score=46.9]; Scavenger receptor cysteine-rich domain [PF00530.20, score=43.8]} {RNA1509_39101} {RNA1310_14098} {RNA815_2224.1}
55. MligTC455_20076 286 5.97 Mlig455_007438

Neo: Int S/G2/M

Age: -

0.955 - - 0.955 - - - Mlig455_007438 {REF} {Length: 2184} {TRANSSPLICED} {Pfam: Protein-only RNase P [PF16953.7, score=42.5]} {Smed: dd_Smed_v6_9514_0_2, dd_Smed_v6_9514_0_2, [RH, Score=53.9, Expect=2e-07]} {RNA1509_38344} {RNA1310_10187.1} {RNA815_17698}
56. MligTC455_38573 71 1.47 Mlig455_022072

Neo: -

Age: -

Region-enriched R4: 4.284/0.00046

0.955 - - 0.955 - - - Mlig455_022072 {REF} {Length: 847} {RNA1509_2672} {RNA1310_34757} {RNA815_17394}
57. MligTC455_22813 113 2.35 Mlig455_010801

Neo: Germline

Age: -

Region-specific R4: 6.068

Region-enriched R4: 5.065/0.00000

0.954 - - 0.954 - - - Mlig455_010801 {REF} {Length: 875} {RNA1509_17716} {RNA1310_43674, RNA1509_17716} {RNA1509_17716, RNA815_21234}
58. MligTC455_28939 158 3.3 Mlig455_051092

Neo: Germline

Age: -

Region-specific R4: 6.221

Region-enriched R4: 4.354/0.00000

0.954 - - 0.954 - - - Mlig455_051092 {REF} {Length: 3433} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=62.9]} {RNA1509_17512} {RNA1310_14948} {RNA815_4608.1}
59. MligTC455_45022 194 4.05 Mlig455_024605

Neo: Germline

Age: Up-Down-Down

Region-specific R4: 4.229

Region-enriched R4: 3.297/0.00005

0.954 - - 0.954 - - - Mlig455_024605 {REF} {Length: 3347} {RNA1509_15667} {RNA1310_7650} {RNA815_39665}
60. MligTC455_03976 126 2.63 Mlig455_017286

Neo: Irradiation

Age: -

Region-specific R4: 6.338

Region-enriched R4: 3.931/0.00045

0.953 - - 0.953 - - - Mlig455_017286 {REF} {Length: 568} {Pfam: RNase H [PF00075.26, score=57.3]} {RNA1509_5045} {RNA1310_667.2} {RNA815_8147}
61. MligTC455_28241 177 3.68 Mlig455_027385

Neo: Irradiation

Age: -

0.953 - - 0.953 - - - Mlig455_027385 {REF} {Length: 2566} {RNA1509_57964} {RNA1310_19828} {RNA815_16572}
62. MligTC455_29129 995 20.73 Mlig455_047958

Neo: -

Age: -

Region-enriched R4: 1.435/0.00610

FBXL14 0.953 - - 0.953 - - - Mlig455_047958 {REF} {Length: 2986} {Pfam: Leucine Rich repeat [PF13516.8, score=63.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=49.0]; F-box-like [PF12937.9, score=32.7]; F-box domain [PF00646.35, score=28.0]; F-box [PF18511.3, score=24.6]; Leucine Rich Repeat [PF00560.35, score=19.1]} {Human: ENSG00000171823, FBXL14, F-box and leucine rich repeat protein 14, [Score=69.3, Expect=6e-12]} {Mouse: ENSMUSG00000041679, Lrrc29, leucine rich repeat containing 29, [RH, Score=165, Expect=2e-43]} {Dmel: FBgn0020257, Ppa, Partner of paired, [Score=69.7, Expect=3e-12]} {Smed: dd_Smed_v6_14890_0_1, dd_Smed_v6_14890_0_1, [Score=51.6, Expect=1e-06]} {RNA1509_6920} {RNA1310_7943.3} {RNA815_1954}
63. MligTC455_10014 765 15.94 Mlig455_054784

Neo: -

Age: Up-Down-Up

Region-enriched R3: 3.005/0.00000
Region-enriched R4: 2.552/0.00078
Region-enriched R5: 1.682/0.01840

CYP2C8 0.952 - - - - - 0.952 Mlig455_054784 {REF} {Length: 2267} {Pfam: Cytochrome P450 [PF00067.24, score=286.1]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=228, Expect=1e-68]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=221, Expect=2e-65]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=219, Expect=3e-65]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=219, Expect=3e-65]} {Mouse: ENSMUSG00000022445, Cyp2d26, cytochrome P450, family 2, subfamily d, polypeptide 26, [Score=229, Expect=8e-69]; ENSMUSG00000091867, Cyp2a22, cytochrome P450, family 2, subfamily a, polypeptide 22, [Score=224, Expect=4e-67]; ENSMUSG00000060407, Cyp2a12, cytochrome P450, family 2, subfamily a, polypeptide 12, [Score=222, Expect=2e-66]; ENSMUSG00000003053, Cyp2c29, cytochrome P450, family 2, subfamily c, polypeptide 29, [Score=221, Expect=5e-66]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=221, Expect=7e-66]; ENSMUSG00000061740, Cyp2d22, cytochrome P450, family 2, subfamily d, polypeptide 22, [Score=218, Expect=1e-64]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=192, Expect=1e-54]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=210, Expect=3e-62]} {Smed: dd_Smed_v6_5344_0_6, dd_Smed_v6_5344_0_6, [Score=199, Expect=7e-58]} {RNA1509_10048} {RNA1310_15951} {RNA815_5705}
64. MligTC455_09210 80 1.66 Mlig455_020657

Neo: Germline

Age: -

Region-enriched R4: 4.181/0.00003

0.95 - - 0.950 - - - Mlig455_020657 {REF} {Length: 1090} {RNA1509_48191} {RNA1310_34576} {RNA815_36561}
65. MligTC455_13590 75 1.56 Mlig455_045750

Neo: Irradiation

Age: Up-Down-Down, logFC(26M/2M)=-1.053

Region-enriched R4: 7.095/0.00171

CSNK1G3 0.95 - - 0.950 - - - Mlig455_045750 {REF} {Length: 1955} {Human: ENSG00000151292, CSNK1G3, casein kinase 1 gamma 3, [Score=65.1, Expect=2e-10]} {Mouse: ENSMUSG00000073563, Csnk1g3, casein kinase 1, gamma 3, [Score=62.4, Expect=7e-10]; ENSMUSG00000032384, Csnk1g1, casein kinase 1, gamma 1, [Score=60.1, Expect=4e-09]; ENSMUSG00000003345, Csnk1g2, casein kinase 1, gamma 2, [Score=60.1, Expect=3e-09]} {Dmel: FBgn0250823, gish, gilgamesh, [Score=55.8, Expect=4e-08]} {Smed: dd_Smed_v6_9844_0_1, dd_Smed_v6_9844_0_1, [Score=60.5, Expect=3e-10]} {RNA1509_39087} {RNA1310_5370, RNA1509_39087} {RNA1509_39087, RNA815_1639}
66. MligTC455_15214 67 1.4 Mlig455_054254

Neo: Int S/G2/M

Age: Up-Up-Down, logFC(26M/2M)=1.458

Region-enriched R4: 4.867/0.00000

TPMT 0.95 - - 0.950 - - - Mlig455_054254 {REF} {Length: 1271} {Pfam: Thiopurine S-methyltransferase (TPMT) [PF05724.13, score=80.4]} {Human: ENSG00000137364, TPMT, thiopurine S-methyltransferase, [Score=75.1, Expect=5e-15]} {Mouse: ENSMUSG00000021376, Tpmt, thiopurine methyltransferase, [Score=63.5, Expect=3e-11]} {Smed: dd_Smed_v6_1495_0_1, dd_Smed_v6_1495_0_1, [RH, Score=78.2, Expect=1e-16]} {RNA1509_43164} {RNA1310_29080} {RNA815_13368}
67. MligTC455_16516 338 7.05 Mlig455_025644

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.431

Region-specific R4: 3.189

Region-enriched R4: 2.435/0.00008

0.95 - - 0.950 - - - Mlig455_025644 {REF} {Length: 1509} {Pfam: N-formylglutamate amidohydrolase [PF05013.14, score=35.9]} {RNA1509_20433, RNA1509_49439} {RNA1310_23627.1, RNA1509_20433, RNA1509_49439} {RNA1509_20433, RNA1509_49439, RNA815_15550}

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