Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_39645 | 162 | 3.37 | Mlig455_020209 | Neo: - Age: - |
SCNN1B | Mlig455_020209 {REF} {Length: 3023} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=191.2]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=62.0, Expect=3e-09]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [Score=51.6, Expect=3e-06]; ENSMUSG00000000216, Scnn1g, sodium channel, nonvoltage-gated 1 gamma, [Score=50.8, Expect=6e-06]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=89.4, Expect=4e-18]} {Smed: dd_Smed_v6_22997_0_1, dd_Smed_v6_22997_0_1, [RH, Score=359, Expect=1e-114]} {RNA1509_55954} {RNA1310_12497, RNA1509_55954} {RNA1509_55954, RNA815_17110} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 4.303 | 2.089 | 0.01303 | 0.32181 | |
RegionR2 | 1.359 | 2.089 | 0.18489 | 0.53717 | |
RegionR3 | 0.446 | 2.089 | 0.54665 | 1.00000 | |
RegionR4 | 0.245 | 2.089 | 0.69930 | 0.98823 | |
RegionR5 | -1.039 | 2.089 | 0.98444 | 1.00000 | |
RegionR6 | -1.948 | 2.089 | 0.99869 | 1.00000 | |
RegionR7 | 1.144 | 2.089 | 0.29000 | 0.92368 | |
RegionR8 | -4.51 | 2.089 | 0.17943 | 0.76180 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -2.414 | 2.089 | 0.20575 | 0.94513 | |
RegenerationR2 | -0.249 | 2.089 | 0.64072 | 0.93154 | |
RegenerationR3 | -0.801 | 2.089 | 0.28982 | 0.72161 | |
RegenerationR4 | -0.915 | 2.089 | 0.30734 | 0.74836 | |
RegenerationR5 | 0.308 | 2.089 | 0.70700 | 0.95426 | |
RegenerationR6 | 1.308 | 2.089 | 0.21197 | 0.55546 | |
RegenerationBL | 2.246 | 2.089 | 0.13042 | 0.43044 | |
RegenerationTP | -0.426 | 2.089 | 0.84998 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_39645 | 162 | 3.37 | Mlig455_020209 | Neo: - Age: - |
SCNN1B | 5 | 1.000 | - | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_020209 {REF} {Length: 3023} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=191.2]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=62.0, Expect=3e-09]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [Score=51.6, Expect=3e-06]; ENSMUSG00000000216, Scnn1g, sodium channel, nonvoltage-gated 1 gamma, [Score=50.8, Expect=6e-06]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=89.4, Expect=4e-18]} {Smed: dd_Smed_v6_22997_0_1, dd_Smed_v6_22997_0_1, [RH, Score=359, Expect=1e-114]} {RNA1509_55954} {RNA1310_12497, RNA1509_55954} {RNA1509_55954, RNA815_17110} |
2. | MligTC455_25516 | 623 | 12.97 | Mlig455_036379, Mlig455_054584 | Neo: - Age: - |
4.252 | 0.959 | - | 0.847 | 0.744 | 0.953 | 0.749 | Mlig455_036379 {REF} {Length: 3088} {RNA1509_28479, RNA1509_52708} {RNA1310_4011, RNA1509_52708} {RNA1509_52708, RNA815_18281.1} Mlig455_054584 {REF} {Length: 3410} {RNA1509_28479} {RNA1310_4011} {RNA815_18281.1} |
|
3. | MligTC455_25517 | 301 | 6.28 | Mlig455_036413 | Neo: - Age: Up-Down-Up |
4.214 | 0.960 | - | 0.868 | 0.727 | 0.950 | 0.709 | Mlig455_036413 {REF} {Length: 1873} {RNA1509_52708} {RNA1310_4011} {RNA815_18281.1} | |
4. | MligTC455_46584 | 107 | 2.22 | Mlig455_010128 | Neo: - Age: Up-Down-Down |
KCNC2 | 3.672 | 0.980 | - | 0.974 | - | 0.843 | 0.875 | Mlig455_010128 {REF} {Length: 1706} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=74.3, Expect=3e-15]} {Mouse: ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=74.3, Expect=3e-16]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=114, Expect=3e-29]} {Celegans: WBGene00001202, egl-36, Potassium voltage-gated channel protein egl-36, [Score=100, Expect=1e-24]} {Smed: dd_Smed_v6_17998_0_1, dd_Smed_v6_17998_0_1, [Score=118, Expect=1e-32]} {RNA1310_24374} {RNA815_11270} |
5. | MligTC455_18697 | 281 | 5.85 | Mlig455_009060 | Neo: - Age: Down-Up-Down |
NEK11 | 3.416 | 0.961 | - | 0.854 | 0.788 | - | 0.813 | Mlig455_009060 {REF} {Length: 2783} {Pfam: Protein kinase domain [PF00069.27, score=137.6]; Ankyrin repeats (3 copies) [PF12796.9, score=97.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=97.3]; Ankyrin repeats (many copies) [PF13637.8, score=60.3]; Ankyrin repeat [PF13606.8, score=54.3]; Ankyrin repeat [PF00023.32, score=53.5]; Ankyrin repeats (many copies) [PF13857.8, score=43.8]; Kinase-like [PF14531.8, score=20.0]} {Human: ENSG00000114670, NEK11, NIMA related kinase 11, [Score=151, Expect=8e-39]} {Mouse: ENSMUSG00000035032, Nek11, NIMA (never in mitosis gene a)-related expressed kinase 11, [Score=145, Expect=3e-36]} {Dmel: FBgn0036896, wnd, wallenda, [Score=97.4, Expect=1e-20]} {Celegans: WBGene00021461, nekl-1, NEK (NEver in mitosis Kinase) Like, [Score=108, Expect=4e-24]} {Smed: dd_Smed_v6_10144_0_4, dd_Smed_v6_10144_0_4, [Score=119, Expect=1e-27]} {RNA1310_7330.1} {RNA815_3574} |
6. | MligTC455_29057 | 679 | 14.15 | Mlig455_011099, Mlig455_011100, Mlig455_058074 | Neo: - |
2.714 | 0.958 | - | - | - | 0.891 | 0.865 | Mlig455_011099 {REF} {Length: 418} {NoTransDecoderORF} {RNA1509_12781} {RNA1310_63.1} {RNA815_23.1} Mlig455_011100 {REF} {Length: 2335} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_54862} {RNA1310_63.1, RNA1509_54862} {RNA1509_54862, RNA815_5170.1} Mlig455_058074 {REF} {Length: 5149} {RNA1509_26411} {RNA1310_63.1, RNA1509_26411} {RNA1509_26411, RNA815_23.1} |
|
7. | MligTC455_52538 | 135 | 2.82 | Mlig455_047397 | Neo: - Age: - |
KCNIP3 | 2.698 | 0.948 | - | 0.996 | 0.754 | - | - | Mlig455_047397 {REF} {Length: 1022} {Pfam: EF-hand domain pair [PF13499.8, score=43.4]; EF hand [PF00036.34, score=41.6]; EF-hand domain [PF13405.8, score=37.6]; EF-hand domain pair [PF13833.8, score=27.5]; EF hand [PF13202.8, score=20.3]} {Human: ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=152, Expect=1e-44]; ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=150, Expect=5e-44]; ENSG00000120049, KCNIP2, potassium voltage-gated channel interacting protein 2, [Score=148, Expect=2e-43]; ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=145, Expect=3e-42]} {Mouse: ENSMUSG00000079056, Kcnip3, Kv channel interacting protein 3, calsenilin, [Score=153, Expect=1e-44]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=150, Expect=3e-44]; ENSMUSG00000025221, Kcnip2, Kv channel-interacting protein 2, [Score=149, Expect=2e-43]; ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=146, Expect=7e-43]} {Dmel: FBgn0265595, CG44422, [Score=160, Expect=2e-46]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=132, Expect=3e-38]} {Smed: dd_Smed_v6_9434_0_1, dd_Smed_v6_9434_0_1, [Score=142, Expect=9e-42]} {RNA1509_26771} {RNA1310_17572} {RNA815_13854} |
8. | MligTC455_38112 | 144 | 3 | Mlig455_035800, Mlig455_068307 | Neo: - |
2.665 | - | - | 0.966 | 0.784 | - | 0.915 | Mlig455_035800 {REF} {Length: 440} {NoTransDecoderORF} Mlig455_068307 {REF} {Length: 195} {NoTransDecoderORF} |
|
9. | MligTC455_04162 | 131 | 2.73 | Mlig455_028924 | Neo: - |
HMCN1 | 2.662 | 0.952 | - | 0.965 | - | 0.745 | - | Mlig455_028924 {REF} {Length: 3929} {Pfam: Immunoglobulin domain [PF13927.8, score=144.9]; Immunoglobulin I-set domain [PF07679.18, score=119.8]; Immunoglobulin domain [PF13895.8, score=113.4]; Immunoglobulin domain [PF00047.27, score=102.3]; Immunoglobulin V-set domain [PF07686.19, score=36.7]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=35.3]; Immunoglobulin C1-set domain [PF07654.17, score=23.3]; C17orf99 Ig domain [PF17736.3, score=20.9]; Immunoglobulin domain [PF18452.3, score=19.8]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=103, Expect=2e-21]; ENSG00000148357, HMCN2, hemicentin 2, [Score=100, Expect=8e-21]} {Mouse: ENSMUSG00000051747, Ttn, titin, [Score=107, Expect=5e-23]; ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=103, Expect=7e-22]} {Dmel: FBgn0000547, ed, echinoid, [Score=147, Expect=2e-35]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=100, Expect=3e-21]} {Smed: dd_Smed_v6_13903_0_1, dd_Smed_v6_13903_0_1, [Score=162, Expect=2e-40]} {RNA1310_26618} {RNA815_41641} |
10. | MligTC455_24909 | 81 | 1.68 | Mlig455_068894 | Neo: - Age: Up-Down-Down |
2.658 | 0.968 | - | - | 0.922 | - | 0.768 | Mlig455_068894 {REF} {Length: 2438} {Pfam: Cadherin domain [PF00028.19, score=22.7]} {Smed: dd_Smed_v6_7807_0_1, dd_Smed_v6_7807_0_1, [Score=64.3, Expect=7e-11]} {RNA1509_42240} {RNA1310_35503} {RNA815_25856} | |
11. | MligTC455_30274 | 155 | 3.23 | Mlig455_002414, Mlig455_055113 | Neo: - Age: - Region-enriched R4: 3.282/0.00489 |
2.641 | 0.945 | - | 0.963 | 0.733 | - | - | Mlig455_002414 {REF} {Length: 2399} {Celegans: WBGene00016348, C33E10.6, [RH, Score=276, Expect=4e-80]} {Smed: dd_Smed_v6_9974_1_7, dd_Smed_v6_9974_1_7, [Score=279, Expect=9e-85]} {RNA1509_8946} {RNA1310_3396.1} {RNA815_1342.1} Mlig455_055113 {REF} {Length: 375} {NoTransDecoderORF} {RNA1509_51941} {RNA1310_3396.1} {RNA815_1342.1} |
|
12. | MligTC455_39463 | 228 | 4.76 | Mlig455_025914, Mlig455_025946 | Neo: - Age: - Regeneration-downregulated R4: -3.846 Regeneration-depleted R4: -3.846 |
2.633 | - | - | 0.988 | - | 0.722 | 0.923 | Mlig455_025914 {REF} {Length: 1257} {RNA1310_37139.1} {RNA815_50944} Mlig455_025946 {REF} {Length: 2808} {tRNA: Ala(CGC),pseudo, score=22.1} {Pfam: Lectin C-type domain [PF00059.23, score=35.2]} {Smed: dd_Smed_v6_84586_0_1, dd_Smed_v6_84586_0_1, [RH, Score=53.1, Expect=4e-09]} {RNA1509_4810} {RNA1310_37139.1} {RNA815_40603} |
|
13. | MligTC455_31872 | 115 | 2.4 | Mlig455_031280 | Neo: - Age: - |
2.606 | - | - | 0.975 | - | 0.723 | 0.908 | Mlig455_031280 {REF} {Length: 4437} {RNA1509_44223} {RNA1310_53789} {RNA815_61017} | |
14. | MligTC455_42085 | 234 | 4.88 | Mlig455_003456 | Neo: - Age: - |
KIRREL1 | 2.591 | - | - | 0.963 | 0.763 | - | 0.865 | Mlig455_003456 {REF} {Length: 3845} {TRANSSPLICED} {Pfam: Immunoglobulin domain [PF13927.8, score=111.2]; Immunoglobulin I-set domain [PF07679.18, score=85.2]; Immunoglobulin domain [PF13895.8, score=72.1]; Immunoglobulin domain [PF00047.27, score=68.2]; Immunoglobulin V-set domain [PF07686.19, score=40.7]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=26.0]} {Human: ENSG00000183853, KIRREL1, kirre like nephrin family adhesion molecule 1, [RH, Score=117, Expect=2e-26]; ENSG00000149571, KIRREL3, kirre like nephrin family adhesion molecule 3, [RH, Score=115, Expect=1e-25]} {Mouse: ENSMUSG00000032036, Kirrel3, kirre like nephrin family adhesion molecule 3, [RH, Score=117, Expect=2e-26]; ENSMUSG00000041734, Kirrel, kirre like nephrin family adhesion molecule 1, [RH, Score=116, Expect=5e-26]} {Dmel: FBgn0085420, DIP-delta, Dpr-interacting protein delta, [Score=60.8, Expect=3e-09]} {Celegans: WBGene00006365, syg-1, Synaptogenesis protein syg-1, [RH, Score=99.8, Expect=3e-21]} {Smed: dd_Smed_v6_12118_0_1, dd_Smed_v6_12118_0_1, [RH, Score=226, Expect=8e-62]} {RNA1509_42885} {RNA1310_3333, RNA1509_42885} {RNA1509_42885, RNA815_3466} |
15. | MligTC455_51947 | 234 | 4.87 | Mlig455_048043, Mlig455_048063 | Neo: - Age: Down-Up-Down Regeneration-downregulated R4: -3.965 Regeneration-depleted R4: -3.965 |
NPFFR2 | 2.577 | 0.875 | - | 0.992 | 0.710 | - | - | Mlig455_048043 {REF} {Length: 2655} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=149.4]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=28.0]} {Human: ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=136, Expect=8e-35]; ENSG00000164128, NPY1R, neuropeptide Y receptor Y1, [Score=130, Expect=5e-33]} {Mouse: ENSMUSG00000048337, Npy4r, neuropeptide Y receptor Y4, [Score=134, Expect=2e-34]; ENSMUSG00000035528, Npffr2, neuropeptide FF receptor 2, [Score=134, Expect=3e-34]; ENSMUSG00000036437, Npy1r, neuropeptide Y receptor Y1, [Score=130, Expect=5e-33]; ENSMUSG00000038071, Npy6r, neuropeptide Y receptor Y6, [Score=130, Expect=2e-33]} {Dmel: FBgn0037408, NPFR, Neuropeptide F receptor, [RH, Score=200, Expect=2e-58]} {Celegans: WBGene00016110, npr-11, Putative neuropeptide Y receptor 11, [RH, Score=164, Expect=9e-46]} {Smed: dd_Smed_v6_16725_0_1, dd_Smed_v6_16725_0_1, [RH, Score=266, Expect=8e-84]} {RNA1509_49794} {RNA1310_30047.1} {RNA815_32644} Mlig455_048063 {REF} {Length: 2727} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=149.4]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=28.0]} {Human: ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=136, Expect=7e-35]; ENSG00000164128, NPY1R, neuropeptide Y receptor Y1, [Score=130, Expect=8e-33]} {Mouse: ENSMUSG00000035528, Npffr2, neuropeptide FF receptor 2, [Score=134, Expect=3e-34]; ENSMUSG00000048337, Npy4r, neuropeptide Y receptor Y4, [Score=134, Expect=1e-34]; ENSMUSG00000038071, Npy6r, neuropeptide Y receptor Y6, [Score=130, Expect=2e-33]; ENSMUSG00000036437, Npy1r, neuropeptide Y receptor Y1, [Score=129, Expect=5e-33]} {Dmel: FBgn0037408, NPFR, Neuropeptide F receptor, [RH, Score=200, Expect=3e-58]} {Celegans: WBGene00016110, npr-11, Putative neuropeptide Y receptor 11, [RH, Score=164, Expect=9e-46]} {Smed: dd_Smed_v6_16725_0_1, dd_Smed_v6_16725_0_1, [RH, Score=266, Expect=7e-84]} {RNA1509_49794} {RNA1310_30047.1, RNA1509_49794} {RNA1509_49794, RNA815_32644} |
16. | MligTC455_28189 | 1402 | 29.22 | Mlig455_021454, Mlig455_029274, Mlig455_043974 | Neo: - Age: Down-Up-Down |
2.572 | - | - | - | 0.814 | 0.967 | 0.791 | Mlig455_021454 {REF} {Length: 2869} {TRANSSPLICED} {RNA1509_51272} {RNA1310_143.1} {RNA815_104.1} Mlig455_029274 {REF} {Length: 3704} {RNA1509_51272} {RNA1310_143.1} {RNA815_104.1} Mlig455_043974 {REF} {Length: 5826} {RNA1509_16132} {RNA1310_143.1} {RNA815_104.1} |
|
17. | MligTC455_29546 | 285 | 5.94 | Mlig455_053809 | Neo: - Age: - Regeneration-upregulated BL: 3.366 Regeneration-enriched BL: 3.366 |
2.55 | 0.966 | - | 0.882 | 0.702 | - | - | Mlig455_053809 {REF} {Length: 7083} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=28.7]} {RNA1509_34867} {RNA1310_17404.1} {RNA815_5685.2} | |
18. | MligTC455_21946 | 173 | 3.59 | Mlig455_018218 | Neo: - Age: - Region-enriched R2: 3.881/0.00497 |
CDH18 | 2.548 | 0.959 | - | - | 0.757 | - | 0.832 | Mlig455_018218 {REF} {Length: 4227} {Pfam: Cadherin cytoplasmic region [PF01049.19, score=86.9]; Laminin G domain [PF02210.26, score=84.1]; Laminin G domain [PF00054.25, score=59.1]; EGF-like domain [PF00008.29, score=34.5]; Human growth factor-like EGF [PF12661.9, score=20.0]} {Human: ENSG00000145526, CDH18, cadherin 18, [Score=107, Expect=3e-23]} {Mouse: ENSMUSG00000040420, Cdh18, cadherin 18, [Score=107, Expect=3e-23]; ENSMUSG00000107269, Celsr3, cadherin, EGF LAG seven-pass G-type receptor 3, [Score=105, Expect=1e-22]; ENSMUSG00000023473, Celsr3, cadherin, EGF LAG seven-pass G-type receptor 3, [Score=105, Expect=1e-22]} {Dmel: FBgn0015609, CadN, Cadherin-N, [Score=246, Expect=2e-67]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [Score=94.4, Expect=2e-19]} {Smed: dd_Smed_v6_9254_0_1, dd_Smed_v6_9254_0_1, [RH, Score=72.4, Expect=6e-13]} {RNA1509_55246} {RNA1310_146.1} {RNA815_6414} |
19. | MligTC455_51821 | 207 | 4.32 | Mlig455_034943 | Neo: - Age: - |
ZDHHC17 | 2.539 | 0.956 | - | - | 0.711 | - | 0.872 | Mlig455_034943 {REF} {Length: 2788} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=95.6]; DHHC palmitoyltransferase [PF01529.22, score=88.3]; Ankyrin repeats (many copies) [PF13857.8, score=73.4]; Ankyrin repeats (many copies) [PF13637.8, score=73.3]; Ankyrin repeat [PF13606.8, score=71.9]; Ankyrin repeat [PF00023.32, score=60.9]} {Human: ENSG00000186908, ZDHHC17, zinc finger DHHC-type containing 17, [Score=171, Expect=1e-45]} {Mouse: ENSMUSG00000035798, Zdhhc17, zinc finger, DHHC domain containing 17, [Score=167, Expect=2e-44]} {Dmel: FBgn0029137, Patsas, [Score=347, Expect=1e-112]} {Celegans: WBGene00044071, dhhc-14, Palmitoyltransferase, [Score=110, Expect=1e-25]} {Smed: dd_Smed_v6_16314_0_1, dd_Smed_v6_16314_0_1, [RH, Score=257, Expect=3e-79]} {RNA1509_23644, RNA1509_58425} {RNA1310_10451.2, RNA1509_23644, RNA1509_58425} {RNA1509_23644, RNA1509_58425, RNA815_5451} |
20. | MligTC455_42598 | 125 | 2.61 | Mlig455_046563 | Neo: - Age: Up-Down-Down |
EML1 | 2.536 | - | - | 0.963 | - | 0.716 | 0.857 | Mlig455_046563 {REF} {Length: 4903} {Pfam: HELP motif [PF03451.16, score=64.1]; WD domain, G-beta repeat [PF00400.34, score=32.8]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=29.2]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=25.5]} {Human: ENSG00000066629, EML1, echinoderm microtubule associated protein like 1, [Score=261, Expect=1e-72]; ENSG00000125746, EML2, echinoderm microtubule associated protein like 2, [Score=260, Expect=2e-72]} {Mouse: ENSMUSG00000058070, Eml1, echinoderm microtubule associated protein like 1, [Score=268, Expect=4e-75]; ENSMUSG00000040811, Eml2, echinoderm microtubule associated protein like 2, [Score=267, Expect=1e-74]} {Dmel: FBgn0259099, DCX-EMAP, Doublecortin-domain-containing echinoderm-microtubule-associated protein, [Score=214, Expect=3e-56]} {Celegans: WBGene00001248, elp-1, Echinoderm microtubule-associated protein-like elp-1, [Score=140, Expect=1e-33]} {Smed: dd_Smed_v6_14226_0_1, dd_Smed_v6_14226_0_1, [Score=323, Expect=4e-92]} {RNA1310_20242} {RNA815_18784} |
21. | MligTC455_17393 | 345 | 7.18 | Mlig455_019018, Mlig455_055685 | Neo: - Age: - |
ANKDD1A | 2.521 | - | - | 0.968 | 0.751 | 0.802 | - | Mlig455_019018 {REF} {Length: 2636} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=191.1]; Ankyrin repeats (many copies) [PF13637.8, score=165.7]; Ankyrin repeat [PF13606.8, score=151.2]; Ankyrin repeats (many copies) [PF13857.8, score=149.5]; Ankyrin repeat [PF00023.32, score=143.3]; Death domain [PF00531.24, score=29.5]} {Human: ENSG00000166839, ANKDD1A, ankyrin repeat and death domain containing 1A, [RH, Score=266, Expect=9e-82]} {Mouse: ENSMUSG00000066510, Ankdd1a, ankyrin repeat and death domain containing 1A, [RH, Score=273, Expect=2e-84]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=139, Expect=6e-34]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=131, Expect=1e-31]} {Smed: dd_Smed_v6_7532_0_1, dd_Smed_v6_7532_0_1, [RH, Score=464, Expect=2e-158]} {RNA1509_56207} {RNA1310_4362} {RNA815_20274} Mlig455_055685 {REF} {Length: 2672} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=191.4]; Ankyrin repeats (many copies) [PF13637.8, score=165.4]; Ankyrin repeat [PF13606.8, score=149.6]; Ankyrin repeats (many copies) [PF13857.8, score=148.6]; Ankyrin repeat [PF00023.32, score=142.4]; Death domain [PF00531.24, score=29.5]} {Human: ENSG00000166839, ANKDD1A, ankyrin repeat and death domain containing 1A, [RH, Score=267, Expect=7e-82]} {Mouse: ENSMUSG00000066510, Ankdd1a, ankyrin repeat and death domain containing 1A, [RH, Score=273, Expect=2e-84]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=137, Expect=1e-33]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=131, Expect=1e-31]} {Smed: dd_Smed_v6_7532_0_1, dd_Smed_v6_7532_0_1, [RH, Score=466, Expect=7e-159]} {RNA1509_56207} {RNA1310_4362, RNA1509_56207} {RNA1509_56207, RNA815_20274} |
22. | MligTC455_46052 | 159 | 3.31 | Mlig455_020714 | Neo: - Age: - Region-enriched R2: 2.603/0.01508 |
TRAF5 | 2.508 | 0.980 | - | 0.754 | - | 0.774 | - | Mlig455_020714 {REF} {Length: 919} {Human: ENSG00000082512, TRAF5, TNF receptor associated factor 5, [Score=90.5, Expect=3e-20]} {Mouse: ENSMUSG00000111385, Traf5, TNF receptor-associated factor 5, [Score=88.2, Expect=1e-20]; ENSMUSG00000026637, Traf5, TNF receptor-associated factor 5, [Score=88.2, Expect=1e-20]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=73.6, Expect=8e-15]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [Score=98.6, Expect=1e-23]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [Score=135, Expect=1e-36]} {RNA1310_36792.1} {RNA815_40908} |
23. | MligTC455_33949 | 219 | 4.56 | Mlig455_030087, Mlig455_043225 | Neo: - Age: Down-Down-Down |
THAP9 | 2.507 | 0.953 | - | - | 0.815 | 0.739 | - | Mlig455_030087 {REF} {Length: 5685} {TRANSSPLICED} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=117.4]; Transposase protein [PF12017.10, score=28.9]} {Human: ENSG00000168152, THAP9, THAP domain containing 9, [Score=212, Expect=5e-56]} {RNA1509_45496} {RNA1310_1582} {RNA815_252.1} Mlig455_043225 {REF} {Length: 3516} {RNA1509_29843} {RNA1310_14922.1} {RNA815_27718} |
24. | MligTC455_39896 | 196 | 4.08 | Mlig455_013184 | Neo: - Age: - |
PAK2 | 2.493 | 0.781 | - | 0.965 | 0.747 | - | - | Mlig455_013184 {REF} {Length: 3893} {Pfam: Protein kinase domain [PF00069.27, score=221.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=158.5]; P21-Rho-binding domain [PF00786.30, score=33.1]; Kinase-like [PF14531.8, score=27.7]; ABC1 atypical kinase-like domain [PF03109.18, score=24.0]; Phosphotransferase enzyme family [PF01636.25, score=19.7]} {Human: ENSG00000180370, PAK2, p21 (RAC1) activated kinase 2, [Score=308, Expect=3e-97]; ENSG00000149269, PAK1, p21 (RAC1) activated kinase 1, [Score=307, Expect=1e-96]} {Mouse: ENSMUSG00000030774, Pak1, p21 (RAC1) activated kinase 1, [Score=308, Expect=4e-97]; ENSMUSG00000022781, Pak2, p21 (RAC1) activated kinase 2, [Score=307, Expect=7e-97]} {Dmel: FBgn0267698, Pak, p21-activated kinase, [Score=280, Expect=8e-85]} {Celegans: WBGene00003144, max-2, Serine/threonine-protein kinase max-2, [Score=269, Expect=7e-86]} {Smed: dd_Smed_v6_1765_0_1, dd_Smed_v6_1765_0_1, [Score=331, Expect=2e-107]} {RNA1509_26775} {RNA1310_17385, RNA1509_26775} {RNA1509_26775, RNA815_3384} |
25. | MligTC455_25998 | 449 | 9.36 | Mlig455_057277 | Neo: - Age: logFC(26M/2M)=-0.387 |
DZANK1 | 2.491 | 0.967 | - | - | 0.777 | - | 0.747 | Mlig455_057277 {REF} {Length: 3625} {TRANSSPLICED} {Pfam: Double zinc ribbon [PF12773.9, score=50.6]; Ankyrin repeats (3 copies) [PF12796.9, score=50.0]; Ankyrin repeats (many copies) [PF13637.8, score=46.7]; Fn3 associated [PF13287.8, score=46.4]; Chitobiase/beta-hexosaminidase C-terminal domain [PF13290.8, score=44.9]; Ankyrin repeat [PF00023.32, score=38.8]; Ankyrin repeats (many copies) [PF13857.8, score=36.4]; Ankyrin repeat [PF13606.8, score=35.9]} {Human: ENSG00000089091, DZANK1, double zinc ribbon and ankyrin repeat domains 1, [RH, Score=391, Expect=5e-124]} {Mouse: ENSMUSG00000037259, Dzank1, double zinc ribbon and ankyrin repeat domains 1, [RH, Score=377, Expect=9e-119]} {Dmel: FBgn0263601, mib1, mind bomb 1, [Score=61.2, Expect=3e-09]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=54.7, Expect=2e-07]} {Smed: dd_Smed_v6_9848_0_1, dd_Smed_v6_9848_0_1, [RH, Score=469, Expect=5e-154]} {RNA1509_15711, RNA1509_56817} {RNA1310_7790.1, RNA1509_15711, RNA1509_56817} {RNA1509_15711, RNA1509_56817, RNA815_13429} |
26. | MligTC455_44120 | 125 | 2.61 | Mlig455_041513 | Neo: - Age: Up-Down-Down Region-enriched R2: 7.169/0.00020 |
2.484 | 0.969 | - | - | - | 0.813 | 0.702 | Mlig455_041513 {REF} {Length: 644} {NoTransDecoderORF} {RNA1310_39164} {RNA815_4344} | |
27. | MligTC455_54013 | 602 | 12.55 | Mlig455_013271 | Neo: - Age: Down-Up-Up |
NLRC3 | 2.421 | 0.978 | - | - | 0.738 | 0.705 | - | Mlig455_013271 {REF} {Length: 2160} {Human: ENSG00000167984, NLRC3, NLR family CARD domain containing 3, [Score=71.6, Expect=3e-12]} {Mouse: ENSMUSG00000059114, Lrrc74a, leucine rich repeat containing 74A, [Score=86.7, Expect=1e-17]} {Dmel: FBgn0033212, LRR, Leucine-rich repeat, [Score=67.8, Expect=2e-11]} {Smed: dd_Smed_v6_15909_0_1, dd_Smed_v6_15909_0_1, [Score=84.0, Expect=5e-17]} {RNA1509_4953} {RNA1310_8767.1} {RNA815_3260} |
28. | MligTC455_37343 | 240 | 4.99 | Mlig455_024086 | Neo: - Age: Up-Down-Up Region-enriched R8: 2.659/0.04266 |
2.402 | - | - | 0.978 | 0.723 | 0.701 | - | Mlig455_024086 {REF} {Length: 4209} {RNA1509_36528, RNA1509_59718} {RNA1310_12514, RNA1509_36528, RNA1509_59718} {RNA1509_36528, RNA1509_59718, RNA815_21020} | |
29. | MligTC455_00722 | 98 | 2.04 | Mlig455_029527 | Neo: - Age: - |
1.937 | 0.970 | - | 0.967 | - | - | - | Mlig455_029527 {REF} {Length: 63} {NoTransDecoderORF} | |
30. | MligTC455_10921 | 431 | 8.98 | Mlig455_021841, Mlig455_021917 | Neo: - Age: Up-Down-Down |
GRM5 | 1.934 | 0.944 | - | 0.990 | - | - | - | Mlig455_021841 {REF} {Length: 9007} {Pfam: Receptor family ligand binding region [PF01094.30, score=472.4]} {Human: ENSG00000168959, GRM5, glutamate metabotropic receptor 5, [Score=202, Expect=2e-51]; ENSG00000198822, GRM3, glutamate metabotropic receptor 3, [Score=201, Expect=8e-52]} {Mouse: ENSMUSG00000049583, Grm5, glutamate receptor, metabotropic 5, [Score=201, Expect=3e-51]; ENSMUSG00000003974, Grm3, glutamate receptor, metabotropic 3, [Score=197, Expect=7e-51]} {Dmel: FBgn0050361, mtt, mangetout, [Score=140, Expect=8e-33]} {Celegans: WBGene00003232, mgl-1, Probable metabotropic glutamate receptor mgl-1, [Score=128, Expect=2e-29]} {Smed: dd_Smed_v6_32826_0_1, dd_Smed_v6_32826_0_1, [Score=172, Expect=3e-44]} {RNA1509_2414} {RNA1310_178.1} {RNA815_189} Mlig455_021917 {REF} {Length: 9090} {Pfam: Receptor family ligand binding region [PF01094.30, score=470.8]; 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=81.0]} {Human: ENSG00000168959, GRM5, glutamate metabotropic receptor 5, [Score=204, Expect=6e-52]; ENSG00000198822, GRM3, glutamate metabotropic receptor 3, [Score=201, Expect=7e-52]} {Mouse: ENSMUSG00000049583, Grm5, glutamate receptor, metabotropic 5, [Score=201, Expect=2e-51]; ENSMUSG00000003974, Grm3, glutamate receptor, metabotropic 3, [Score=198, Expect=5e-51]} {Dmel: FBgn0050361, mtt, mangetout, [Score=167, Expect=8e-41]} {Celegans: WBGene00003232, mgl-1, Probable metabotropic glutamate receptor mgl-1, [Score=130, Expect=9e-30]} {Smed: dd_Smed_v6_32826_0_1, dd_Smed_v6_32826_0_1, [Score=172, Expect=3e-44]} {RNA1509_2414} {RNA1310_178.1, RNA1509_2414} {RNA1509_2414, RNA815_189} |
31. | MligTC455_54203 | 182 | 3.79 | Mlig455_061249 | Neo: - Age: - |
MYH7 | 1.912 | - | - | 0.955 | - | 0.957 | - | Mlig455_061249 {REF} {Length: 1536} {Pfam: Myosin tail [PF01576.21, score=90.6]} {Human: ENSG00000092054, MYH7, myosin heavy chain 7, [Score=200, Expect=8e-57]; ENSG00000197616, MYH6, myosin heavy chain 6, [Score=198, Expect=4e-56]; ENSG00000264424, MYH4, myosin heavy chain 4, [Score=191, Expect=2e-53]; ENSG00000125414, MYH2, myosin heavy chain 2, [Score=190, Expect=4e-53]} {Mouse: ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [Score=201, Expect=4e-57]; ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [Score=194, Expect=8e-55]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [Score=192, Expect=3e-54]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [Score=191, Expect=1e-53]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [Score=282, Expect=2e-85]} {Celegans: WBGene00003515, myo-3, Myosin-3, [Score=241, Expect=2e-71]} {Smed: dd_Smed_v6_432_0_1, dd_Smed_v6_432_0_1, [Score=285, Expect=9e-87]} {RNA1509_55838} {RNA1310_1388} {RNA815_21073} |
32. | MligTC455_46391 | 204 | 4.24 | Mlig455_034052, Mlig455_034075 | Neo: - Age: - |
1.911 | 0.968 | - | 0.943 | - | - | - | Mlig455_034052 {REF} {Length: 1129} {TRANSSPLICED} {Pfam: Sleepless protein [PF17064.7, score=37.0]} {Dmel: FBgn0260499, qvr, quiver, [RH, Score=80.5, Expect=2e-19]} {Smed: dd_Smed_v6_16907_0_2, dd_Smed_v6_16907_0_2, [Score=75.1, Expect=1e-17]} {RNA1310_53545} {RNA815_30194} Mlig455_034075 {REF} {Length: 1159} {Pfam: Sleepless protein [PF17064.7, score=36.8]} {Dmel: FBgn0260499, qvr, quiver, [RH, Score=78.6, Expect=9e-19]} {Smed: dd_Smed_v6_16907_0_2, dd_Smed_v6_16907_0_2, [Score=78.6, Expect=6e-19]} {RNA1310_53545} {RNA815_30194} |
|
33. | MligTC455_51011 | 108 | 2.26 | Mlig455_028317 | Neo: Irradiation Age: Up-Down-Down |
RABGAP1 | 1.906 | 0.964 | - | 0.942 | - | - | - | Mlig455_028317 {REF} {Length: 6575} {TRANSSPLICED} {Pfam: Rab-GTPase-TBC domain [PF00566.20, score=168.4]; Kinesin protein [PF12473.10, score=25.5]} {Human: ENSG00000011454, RABGAP1, RAB GTPase activating protein 1, [RH, Score=424, Expect=4e-131]} {Mouse: ENSMUSG00000035437, Rabgap1, RAB GTPase activating protein 1, [RH, Score=444, Expect=1e-138]} {Dmel: FBgn0035879, GAPcenA, GTPase activating protein and centrosome-associated, [RH, Score=335, Expect=5e-99]} {Celegans: WBGene00018075, tbc-11, TBC (Tre-2/Bub2/Cdc16) domain family, [RH, Score=354, Expect=1e-106]} {Smed: dd_Smed_v6_3940_0_3, dd_Smed_v6_3940_0_3, [RH, Score=401, Expect=4e-123]} {RNA1509_58329, RNA1509_8557} {RNA1310_691.1, RNA1509_58329} {RNA1509_58329, RNA815_1795} |
34. | MligTC455_41868 | 289 | 6.02 | Mlig455_041344, Mlig455_056230 | Neo: - Age: - |
ZNF362 | 1.884 | 0.973 | - | - | - | - | 0.911 | Mlig455_041344 {REF} {Length: 2545} {Pfam: Zinc-finger double domain [PF13465.8, score=54.5]; Zinc finger, C2H2 type [PF00096.28, score=35.0]} {Human: ENSG00000160094, ZNF362, zinc finger protein 362, [RH, Score=183, Expect=9e-52]; ENSG00000126746, ZNF384, zinc finger protein 384, [RH, Score=179, Expect=3e-49]} {Mouse: ENSMUSG00000038346, Zfp384, zinc finger protein 384, [RH, Score=183, Expect=1e-50]; ENSMUSG00000028799, Zfp362, zinc finger protein 362, [RH, Score=183, Expect=5e-52]} {Dmel: FBgn0267337, rn, rotund, [RH, Score=187, Expect=7e-51]} {Celegans: WBGene00003015, lin-29, Transcription factor, [RH, Score=163, Expect=2e-44]} {Smed: dd_Smed_v6_18940_0_1, dd_Smed_v6_18940_0_1, [Score=275, Expect=2e-84]} {RNA1509_19836} {RNA1310_5398} {RNA815_17827} Mlig455_056230 {REF} {Length: 1821} {TRANSSPLICED} {Pfam: Zinc-finger double domain [PF13465.8, score=78.5]; Zinc finger, C2H2 type [PF00096.28, score=41.6]; C2H2-type zinc finger [PF13894.8, score=30.9]; Chorion family 2 [PF03964.17, score=19.6]; DSBA-like thioredoxin domain [PF01323.22, score=18.4]} {Human: ENSG00000160094, ZNF362, zinc finger protein 362, [Score=172, Expect=4e-50]; ENSG00000126746, ZNF384, zinc finger protein 384, [Score=167, Expect=2e-47]} {Mouse: ENSMUSG00000028799, Zfp362, zinc finger protein 362, [Score=172, Expect=2e-50]; ENSMUSG00000038346, Zfp384, zinc finger protein 384, [Score=167, Expect=2e-47]} {Dmel: FBgn0267337, rn, rotund, [RH, Score=169, Expect=2e-47]} {Celegans: WBGene00003015, lin-29, Transcription factor, [RH, Score=160, Expect=6e-46]} {Smed: dd_Smed_v6_18940_0_1, dd_Smed_v6_18940_0_1, [Score=255, Expect=5e-80]} {RNA1509_19836} {RNA1310_5398, RNA1509_19836} {RNA1509_19836, RNA815_17827} |
35. | MligTC455_52818 | 520 | 10.84 | Mlig455_022841 | Neo: Int S/G2/M |
IMPDH1 | 1.876 | 0.894 | - | 0.982 | - | - | - | Mlig455_022841 {REF} {Length: 3806} {Pfam: IMP dehydrogenase / GMP reductase domain [PF00478.27, score=449.3]; Nitronate monooxygenase [PF03060.17, score=56.0]; CBS domain [PF00571.30, score=41.5]; FMN-dependent dehydrogenase [PF01070.20, score=40.6]; Histidine biosynthesis protein [PF00977.23, score=27.4]; Thiazole biosynthesis protein ThiG [PF05690.16, score=18.4]} {Human: ENSG00000106348, IMPDH1, inosine monophosphate dehydrogenase 1, [RH, Score=790, Expect=0.0]; ENSG00000178035, IMPDH2, inosine monophosphate dehydrogenase 2, [RH, Score=776, Expect=0.0]} {Mouse: ENSMUSG00000003500, Impdh1, inosine monophosphate dehydrogenase 1, [RH, Score=785, Expect=0.0]; ENSMUSG00000062867, Impdh2, inosine monophosphate dehydrogenase 2, [RH, Score=773, Expect=0.0]} {Dmel: FBgn0003204, ras, raspberry, [RH, Score=709, Expect=0.0]} {Celegans: WBGene00020682, T22D1.3, Inosine-5'-monophosphate dehydrogenase, [RH, Score=543, Expect=0.0]} {Smed: dd_Smed_v6_4321_0_2, dd_Smed_v6_4321_0_2, [RH, Score=755, Expect=0.0]} {RNA1509_4134, RNA1509_47560} {RNA1310_8483.1, RNA1509_47560} {RNA1509_47560, RNA815_4082} |
36. | MligTC455_45300 | 333 | 6.94 | Mlig455_020728 | Neo: - Age: - |
1.866 | - | - | 0.984 | - | - | 0.882 | Mlig455_020728 {REF} {Length: 4245} {Pfam: C2H2-type zinc finger [PF13894.8, score=40.5]; Zinc finger, C2H2 type [PF00096.28, score=26.8]; Cysteine rich domain with multizinc binding regions [PF17979.3, score=23.7]} {Dmel: FBgn0036725, CG18265, [RH, Score=55.5, Expect=3e-07]} {Celegans: WBGene00000995, die-1, Dorsal Intercalation and Elongation defect, [RH, Score=58.9, Expect=2e-08]} {Smed: dd_Smed_v6_34785_0_1, dd_Smed_v6_34785_0_1, [RH, Score=121, Expect=1e-28]} {RNA1509_19455} {RNA1310_2166.1, RNA1509_19455} {RNA1509_19455, RNA815_12667} | |
37. | MligTC455_36609 | 196 | 4.08 | Mlig455_018538 | Neo: - Age: - |
ANKRD18B | 1.863 | 0.974 | - | - | - | 0.889 | - | Mlig455_018538 {REF} {Length: 4748} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=80.9]; Ankyrin repeats (many copies) [PF13637.8, score=66.0]; Ankyrin repeat [PF00023.32, score=58.7]; Ankyrin repeats (many copies) [PF13857.8, score=55.5]; Ankyrin repeat [PF13606.8, score=52.9]} {Human: ENSG00000230453, ANKRD18B, ankyrin repeat domain 18B, [RH, Score=105, Expect=4e-22]} {Mouse: ENSMUSG00000022246, Rai14, retinoic acid induced 14, [Score=100, Expect=8e-21]; ENSMUSG00000020481, Ankrd36, ankyrin repeat domain 36, [Score=96.3, Expect=2e-19]; ENSMUSG00000029517, Ankrd7, ankyrin repeat domain 7, [Score=95.9, Expect=5e-21]} {Dmel: FBgn0037759, CG8526, [Score=68.9, Expect=2e-11]} {Celegans: WBGene00004053, tank-1, Tankyrase-like protein, [Score=72.0, Expect=3e-12]} {Smed: dd_Smed_v6_7813_0_1, dd_Smed_v6_7813_0_1, [Score=82.4, Expect=6e-16]} {RNA1509_17141} {RNA1310_571} {RNA815_5717} |
38. | MligTC455_20558 | 404 | 8.41 | Mlig455_048948 | Neo: - Age: - |
ORAI2 | 1.856 | - | - | 0.977 | 0.879 | - | - | Mlig455_048948 {REF} {Length: 1287} {Pfam: Mediator of CRAC channel activity [PF07856.14, score=191.2]} {Human: ENSG00000160991, ORAI2, ORAI calcium release-activated calcium modulator 2, [RH, Score=179, Expect=1e-55]; ENSG00000276045, ORAI1, ORAI calcium release-activated calcium modulator 1, [RH, Score=179, Expect=9e-55]; ENSG00000285150, ORAI1, ORAI calcium release-activated calcium modulator 1, [RH, Score=179, Expect=1e-55]} {Mouse: ENSMUSG00000039747, Orai2, ORAI calcium release-activated calcium modulator 2, [RH, Score=182, Expect=2e-56]; ENSMUSG00000049686, Orai1, ORAI calcium release-activated calcium modulator 1, [RH, Score=175, Expect=3e-53]} {Dmel: FBgn0041585, olf186-F, [RH, Score=170, Expect=6e-51]} {Celegans: WBGene00015648, orai-1, ORAI (Store-operated calcium channel) homolog, [RH, Score=113, Expect=6e-30]} {Smed: dd_Smed_v6_8774_0_1, dd_Smed_v6_8774_0_1, [RH, Score=174, Expect=2e-54]} {RNA1509_25246} {RNA1310_16799.1} {RNA815_9555.1} |
39. | MligTC455_51126 | 48 | 1.01 | Mlig455_036447 | Neo: - Age: - |
GLRA2 | 1.852 | 0.979 | - | - | 0.873 | - | - | Mlig455_036447 {REF} {Length: 2076} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=154.6]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=110.1]} {Human: ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=318, Expect=6e-103]; ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=316, Expect=5e-102]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=312, Expect=9e-101]} {Mouse: ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=318, Expect=4e-103]; ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=317, Expect=3e-102]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=310, Expect=8e-100]} {Dmel: FBgn0024963, GluClalpha, [Score=291, Expect=2e-92]} {Celegans: WBGene00020767, lgc-40, Ligand-Gated ion Channel, [RH, Score=260, Expect=2e-80]} {Smed: dd_Smed_v6_18238_0_1, dd_Smed_v6_18238_0_1, [Score=258, Expect=3e-80]} {RNA1310_34255} {RNA815_61641} |
40. | MligTC455_13682 | 42 | 0.87 | Mlig455_030673 | Neo: - Age: - |
1.849 | - | - | 0.991 | - | 0.858 | - | Mlig455_030673 {REF} {Length: 2472} {Pfam: gag-polyprotein putative aspartyl protease [PF13975.8, score=21.9]} {RNA1509_51609} {RNA1310_3461} {RNA815_16498} | |
41. | MligTC455_35174 | 342 | 7.13 | Mlig455_009545, Mlig455_054086 | Neo: - Age: Up-Down-Down |
PTPRN2 | 1.847 | 0.890 | - | 0.957 | - | - | - | Mlig455_009545 {REF} {Length: 87} {NoTransDecoderORF} {RNA1509_3577} {RNA1310_173.2} {RNA815_26664} Mlig455_054086 {REF} {Length: 10208} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=222.7]} {Human: ENSG00000155093, PTPRN2, protein tyrosine phosphatase, receptor type N2, [RH, Score=412, Expect=1e-129]} {Mouse: ENSMUSG00000056553, Ptprn2, protein tyrosine phosphatase, receptor type, N polypeptide 2, [RH, Score=407, Expect=7e-128]} {Dmel: FBgn0031294, IA-2, IA-2 protein tyrosine phosphatase, [RH, Score=376, Expect=8e-114]} {Celegans: WBGene00002048, ida-1, IA2; IDA-1 protein; Related to Islet cell Diabetes Autoantigen, [Score=280, Expect=1e-82]} {Smed: dd_Smed_v6_6990_0_1, dd_Smed_v6_6990_0_1, [RH, Score=391, Expect=8e-125]} {RNA1509_34721, RNA1509_41198} {RNA1310_3634, RNA1509_34721, RNA1509_41198} {RNA1509_34721, RNA1509_41198, RNA815_1727.1} |
42. | MligTC455_46120 | 185 | 3.86 | Mlig455_042356 | Neo: - Age: - |
1.845 | - | - | 0.962 | - | - | 0.883 | Mlig455_042356 {REF} {Length: 1296} {RNA1509_23490} {RNA1310_21881} {RNA815_8961} | |
43. | MligTC455_43181 | 570 | 11.88 | Mlig455_000235, Mlig455_058496 | Neo: - Age: Up-Down-Down |
GABRG2 | 1.842 | 0.977 | - | - | 0.865 | - | - | Mlig455_000235 {REF} {Length: 2985} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=28.7]} {Human: ENSG00000113327, GABRG2, gamma-aminobutyric acid type A receptor gamma2 subunit, [Score=71.2, Expect=9e-13]; ENSG00000182256, GABRG3, gamma-aminobutyric acid type A receptor gamma3 subunit, [Score=68.6, Expect=2e-11]; ENSG00000163285, GABRG1, gamma-aminobutyric acid type A receptor gamma1 subunit, [Score=68.6, Expect=2e-11]} {Mouse: ENSMUSG00000055026, Gabrg3, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3, [Score=72.0, Expect=1e-12]; ENSMUSG00000001260, Gabrg1, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1, [Score=70.1, Expect=6e-12]; ENSMUSG00000020436, Gabrg2, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2, [Score=69.7, Expect=7e-12]} {Celegans: WBGene00001512, gab-1, Gamma-aminobutyric acid receptor subunit beta, [Score=51.6, Expect=2e-06]} {Smed: dd_Smed_v6_10171_0_2, dd_Smed_v6_10171_0_2, [Score=440, Expect=3e-144]} {RNA1509_31476} {RNA1310_7448.1} {RNA815_6894} Mlig455_058496 {REF} {Length: 3260} {Smed: dd_Smed_v6_13861_0_2, dd_Smed_v6_13861_0_2, [RH, Score=91.3, Expect=2e-23]} {RNA1509_31476} {RNA1310_7448.1} {RNA815_11721.1} |
44. | MligTC455_23370 | 144 | 3.01 | Mlig455_065633 | Neo: - Age: Down-Up-Up |
1.841 | - | - | 0.956 | - | - | 0.885 | Mlig455_065633 {REF} {Length: 1422} {RNA1509_56375} {RNA1310_29166.1, RNA1509_56375} {RNA1509_56375, RNA815_11123} | |
45. | MligTC455_42088 | 72 | 1.5 | Mlig455_028244 | Neo: - Age: - |
1.838 | - | - | 0.980 | - | 0.858 | - | Mlig455_028244 {REF} {Length: 2632} {RNA1509_40406} {RNA1310_12938} {RNA815_16887} | |
46. | MligTC455_30713 | 277 | 5.78 | Mlig455_044000, Mlig455_050688 | Neo: - Age: - |
TTLL9 | 1.835 | - | - | 0.985 | - | - | 0.850 | Mlig455_044000 {REF} {Length: 2900} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=293.3]; YheC/D like ATP-grasp [PF14398.8, score=28.0]; Sugar-transfer associated ATP-grasp [PF14397.8, score=19.3]} {Human: ENSG00000131044, TTLL9, tubulin tyrosine ligase like 9, [RH, Score=500, Expect=9e-177]} {Mouse: ENSMUSG00000074673, Ttll9, tubulin tyrosine ligase-like family, member 9, [RH, Score=542, Expect=0.0]} {Dmel: FBgn0052238, CG32238, [Score=314, Expect=1e-102]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [RH, Score=383, Expect=9e-131]} {Smed: dd_Smed_v6_13605_0_1, dd_Smed_v6_13605_0_1, [RH, Score=529, Expect=0.0]} {RNA1509_23575, RNA1509_38415, RNA1509_39587} {RNA1310_6106, RNA1509_23575, RNA1509_38415, RNA1509_39587} {RNA1509_23575, RNA1509_38415, RNA1509_39587, RNA815_8243} Mlig455_050688 {REF} {Length: 3812} {TRANSSPLICED} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=291.5]; YheC/D like ATP-grasp [PF14398.8, score=25.9]} {Human: ENSG00000131044, TTLL9, tubulin tyrosine ligase like 9, [RH, Score=509, Expect=3e-175]} {Mouse: ENSMUSG00000074673, Ttll9, tubulin tyrosine ligase-like family, member 9, [RH, Score=553, Expect=0.0]} {Dmel: FBgn0052238, CG32238, [Score=317, Expect=2e-99]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [RH, Score=387, Expect=8e-128]} {Smed: dd_Smed_v6_13605_0_1, dd_Smed_v6_13605_0_1, [RH, Score=539, Expect=0.0]} {RNA1509_38415} {RNA1310_6106} {RNA815_8243} |
47. | MligTC455_09595 | 48 | 1.01 | Mlig455_030009 | Neo: - Age: - |
OPRM1 | 1.832 | - | - | 0.996 | - | 0.836 | - | Mlig455_030009 {REF} {Length: 1508} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=44.4]; Serpentine type 7TM GPCR chemoreceptor Sra [PF02117.18, score=19.7]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=19.6]} {Human: ENSG00000112038, OPRM1, opioid receptor mu 1, [Score=56.2, Expect=5e-08]} {Mouse: ENSMUSG00000000766, Oprm1, opioid receptor, mu 1, [Score=54.7, Expect=9e-08]} {Celegans: WBGene00021510, frpr-19, FMRFamide Peptide Receptor family, [Score=47.8, Expect=7e-06]} {RNA1310_43388} {RNA815_47203} |
48. | MligTC455_33615 | 269 | 5.59 | Mlig455_030953 | Neo: - |
ASAH2 | 1.832 | 0.857 | - | 0.975 | - | - | - | Mlig455_030953 {REF} {Length: 4824} {Pfam: Neutral/alkaline non-lysosomal ceramidase, N-terminal [PF04734.15, score=704.3]; Neutral/alkaline non-lysosomal ceramidase, C-terminal [PF17048.7, score=155.3]; Major Facilitator Superfamily [PF07690.18, score=146.2]} {Human: ENSG00000188611, ASAH2, N-acylsphingosine amidohydrolase 2, [RH, Score=626, Expect=0.0]} {Mouse: ENSMUSG00000024887, Asah2, N-acylsphingosine amidohydrolase 2, [RH, Score=612, Expect=0.0]} {Dmel: FBgn0039774, CDase, Ceramidase, [RH, Score=595, Expect=0.0]} {Celegans: WBGene00011719, T11G6.4, [Score=201, Expect=2e-55]} {Smed: dd_Smed_v6_1726_0_1, dd_Smed_v6_1726_0_1, [RH, Score=664, Expect=0.0]} {RNA1509_4146} {RNA1310_8395.1} {RNA815_2759} |
49. | MligTC455_52647 | 61 | 1.27 | Mlig455_002539 | Neo: - Age: Down-Up-Down Region-enriched R4: 5.918/0.02084 |
1.828 | - | - | 0.986 | - | - | 0.842 | Mlig455_002539 {REF} {Length: 741} {Pfam: EF-hand domain pair [PF13499.8, score=34.4]; EF hand [PF00036.34, score=30.8]; EF-hand domain [PF13405.8, score=27.2]; EF hand [PF13202.8, score=19.2]; EF-hand domain pair [PF13833.8, score=18.4]} {Smed: dd_Smed_v6_824_0_1, dd_Smed_v6_824_0_1, [Score=89.4, Expect=9e-23]} {RNA1509_7584} {RNA1310_31534.2} {RNA815_19135} | |
50. | MligTC455_25005 | 390 | 8.13 | Mlig455_071003 | Neo: - Age: Down-Down-Up |
1.826 | - | - | 0.872 | - | - | 0.954 | Mlig455_071003 {REF} {Length: 5546} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=54.0]; Capsular polysaccharide synthesis protein [PF05704.14, score=23.4]} {Smed: dd_Smed_v6_42389_0_1, dd_Smed_v6_42389_0_1, [RH, Score=141, Expect=2e-39]} {RNA1509_41978} {RNA1310_22525} {RNA815_38804} | |
51. | MligTC455_16801 | 252 | 5.24 | Mlig455_001186 | Neo: Irradiation Age: - |
ERBB3 | 1.825 | - | - | 0.976 | - | - | 0.849 | Mlig455_001186 {REF} {Length: 5931} {Human: ENSG00000065361, ERBB3, erb-b2 receptor tyrosine kinase 3, [Score=61.6, Expect=5e-10]; ENSG00000178568, ERBB4, erb-b2 receptor tyrosine kinase 4, [Score=58.9, Expect=5e-09]} {Mouse: ENSMUSG00000018166, Erbb3, erb-b2 receptor tyrosine kinase 3, [Score=60.1, Expect=2e-09]; ENSMUSG00000062209, Erbb4, erb-b2 receptor tyrosine kinase 4, [Score=58.9, Expect=4e-09]; ENSMUSG00000020122, Egfr, epidermal growth factor receptor, [Score=58.2, Expect=8e-09]} {Smed: dd_Smed_v6_10624_0_1, dd_Smed_v6_10624_0_1, [Score=51.6, Expect=4e-07]} {RNA1509_7929} {RNA1310_1321, RNA1509_7929} {RNA1509_7929, RNA815_2089} |
52. | MligTC455_28174 | 190 | 3.95 | Mlig455_051788 | Neo: - Age: - |
1.818 | 0.960 | - | 0.858 | - | - | - | Mlig455_051788 {REF} {Length: 560} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_30941} {RNA1310_13121} {RNA815_27783} | |
53. | MligTC455_26092 | 67 | 1.39 | Mlig455_048489 | Neo: - Age: Up-Down-Up, logFC(26M/2M)=0.677 Region-enriched R2: 4.303/0.01110 |
1.817 | 0.985 | - | - | - | 0.832 | - | Mlig455_048489 {REF} {Length: 2319} {Pfam: Lectin C-type domain [PF00059.23, score=23.3]} {RNA1509_25383} {RNA1310_27113} {RNA815_24719} | |
54. | MligTC455_07620 | 312 | 6.49 | Mlig455_068229 | Neo: - Age: logFC(26M/2M)=-0.302 |
UNK | 1.815 | - | - | 0.973 | - | - | 0.842 | Mlig455_068229 {REF} {Length: 5152} {Pfam: Unkempt Zinc finger domain 1 (Znf1) [PF18384.3, score=68.1]; Zinc finger C-x8-C-x5-C-x3-H type (and similar) [PF00642.26, score=24.9]} {Human: ENSG00000132478, UNK, unkempt family zinc finger, [RH, Score=436, Expect=2e-140]} {Mouse: ENSMUSG00000020770, Unk, unkempt family zinc finger, [RH, Score=435, Expect=2e-140]} {Dmel: FBgn0004395, unk, unkempt, [RH, Score=414, Expect=6e-134]} {Celegans: WBGene00016407, C34D10.2, [RH, Score=418, Expect=9e-136]} {Smed: dd_Smed_v6_3128_1_1, dd_Smed_v6_3128_1_1, [RH, Score=483, Expect=5e-160]} {RNA1509_46130, RNA1509_54852, RNA1509_7679} {RNA1310_1262.1, RNA1509_46130, RNA1509_54852, RNA1509_7679} {RNA1509_46130, RNA1509_54852, RNA1509_7679, RNA815_4161} |
55. | MligTC455_24523 | 144 | 2.99 | Mlig455_010636, Mlig455_010724 | Neo: - Age: - Region-enriched R2: 9.355/0.00000 |
RGS6 | 1.813 | 0.980 | - | - | - | 0.833 | - | Mlig455_010636 {REF} {Length: 2512} {Pfam: Regulator of G-protein signalling DHEX domain [PF18148.3, score=118.4]; Regulator of G protein signaling domain [PF00615.21, score=116.4]; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) [PF00610.23, score=31.3]} {Human: ENSG00000182732, RGS6, regulator of G protein signaling 6, [Score=301, Expect=3e-95]} {Mouse: ENSMUSG00000021219, Rgs6, regulator of G-protein signaling 6, [Score=299, Expect=2e-94]; ENSMUSG00000026527, Rgs7, regulator of G protein signaling 7, [Score=290, Expect=6e-91]} {Dmel: FBgn0259927, CG42450, [RH, Score=327, Expect=2e-98]} {Celegans: WBGene00001145, eat-16, [Score=217, Expect=1e-63]} {Smed: dd_Smed_v6_5311_0_1, dd_Smed_v6_5311_0_1, [RH, Score=384, Expect=1e-127]} {RNA1509_59108} {RNA1310_13711, RNA1509_59108} {RNA1509_59108, RNA815_9935} Mlig455_010724 {REF} {Length: 2512} {Pfam: Regulator of G-protein signalling DHEX domain [PF18148.3, score=118.4]; Regulator of G protein signaling domain [PF00615.21, score=113.1]; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) [PF00610.23, score=31.3]} {Human: ENSG00000182732, RGS6, regulator of G protein signaling 6, [Score=299, Expect=2e-94]} {Mouse: ENSMUSG00000021219, Rgs6, regulator of G-protein signaling 6, [Score=297, Expect=2e-93]; ENSMUSG00000026527, Rgs7, regulator of G protein signaling 7, [Score=287, Expect=4e-90]} {Dmel: FBgn0259927, CG42450, [RH, Score=324, Expect=1e-97]} {Celegans: WBGene00001145, eat-16, [Score=214, Expect=8e-63]} {Smed: dd_Smed_v6_5311_0_1, dd_Smed_v6_5311_0_1, [RH, Score=382, Expect=8e-127]} {RNA1509_59108} {RNA1310_13711} {RNA815_9935} |
56. | MligTC455_49957 | 119 | 2.47 | Mlig455_005610, Mlig455_014448 | Neo: - Age: - |
1.812 | - | - | 0.977 | - | 0.835 | - | Mlig455_005610 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=66.2, Expect=4e-13]} {RNA1310_45206} {RNA815_28788} Mlig455_014448 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=63.2, Expect=6e-12]} {RNA1310_45206} {RNA815_28788} |
|
57. | MligTC455_26356 | 62 | 1.3 | Mlig455_042551 | Neo: - |
GRIK2 | 1.805 | - | - | 0.987 | - | 0.818 | - | Mlig455_042551 {REF} {Length: 2917} {Pfam: Ligand-gated ion channel [PF00060.28, score=82.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=60.7]; Receptor family ligand binding region [PF01094.30, score=32.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=27.3]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=144, Expect=9e-35]; ENSG00000152208, GRID2, glutamate ionotropic receptor delta type subunit 2, [Score=141, Expect=7e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=143, Expect=1e-34]; ENSMUSG00000071424, Grid2, glutamate receptor, ionotropic, delta 2, [Score=142, Expect=2e-34]} {Dmel: FBgn0051201, GluRIIE, Glutamate receptor IIE, [Score=119, Expect=3e-27]} {Celegans: WBGene00001616, glr-5, GLutamate Receptor family (AMPA), [Score=123, Expect=2e-28]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=247, Expect=4e-74]} {RNA1310_21865} {RNA815_26044} |
58. | MligTC455_43218 | 137 | 2.86 | Mlig455_025977 | Neo: - Age: - |
1.805 | - | - | 0.984 | 0.821 | - | - | Mlig455_025977 {REF} {Length: 1409} {NoTransDecoderORF} {RNA1509_59012} {RNA1310_127643} | |
59. | MligTC455_49690 | 72 | 1.5 | Mlig455_068367 | Neo: - Age: Down-Down-Up |
1.805 | - | - | 0.988 | - | 0.817 | - | Mlig455_068367 {REF} {Length: 1546} {Smed: dd_Smed_v6_8297_0_1, dd_Smed_v6_8297_0_1, [RH, Score=53.1, Expect=2e-09]} {RNA1509_38073} {RNA1310_34998} {RNA815_20391} | |
60. | MligTC455_36667 | 84 | 1.75 | Mlig455_016177 | Neo: - Age: Up-Down-Down, logFC(26M/2M)=-0.440 Region-enriched R2: 4.490/0.00556 |
1.801 | 0.968 | - | - | - | 0.833 | - | Mlig455_016177 {REF} {Length: 3035} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=47.6]; Immunoglobulin domain [PF13927.8, score=47.0]; Immunoglobulin domain [PF00047.27, score=32.1]; Immunoglobulin domain [PF13895.8, score=27.4]; Natural killer cell receptor 2B4 [PF11465.10, score=26.4]; Immunoglobulin V-set domain [PF07686.19, score=23.5]} {Dmel: FBgn0259245, DIP-beta, Dpr-interacting protein beta, [Score=58.9, Expect=3e-09]} {Celegans: WBGene00006985, zig-8, Zwei Ig domain protein zig-8, [RH, Score=57.0, Expect=4e-09]} {Smed: dd_Smed_v6_21969_0_1, dd_Smed_v6_21969_0_1, [Score=72.0, Expect=6e-14]} {RNA1509_49618} {RNA1310_15195} {RNA815_58259} | |
61. | MligTC455_24900 | 764 | 15.91 | Mlig455_042657, Mlig455_042690 | Neo: - Age: - |
PLCB4 | 1.8 | - | - | 0.982 | - | 0.818 | - | Mlig455_042657 {REF} {Length: 6508} {TRANSSPLICED} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=199.3]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=138.6]; PH domain [PF17787.3, score=109.2]; Protein of unknown function (DUF1154) [PF06631.13, score=47.4]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=41.7]; C2 domain [PF00168.32, score=22.8]} {Human: ENSG00000101333, PLCB4, phospholipase C beta 4, [RH, Score=1296, Expect=0.0]} {Mouse: ENSMUSG00000039943, Plcb4, phospholipase C, beta 4, [RH, Score=1170, Expect=0.0]} {Dmel: FBgn0262738, norpA, no receptor potential A, [RH, Score=565, Expect=4e-180]} {Celegans: WBGene00001177, egl-8, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8, [RH, Score=1127, Expect=0.0]} {Smed: dd_Smed_v6_3221_0_1, dd_Smed_v6_3221_0_1, [RH, Score=1510, Expect=0.0]} {RNA1509_3820} {RNA1310_563.1} {RNA815_911.1} Mlig455_042690 {REF} {Length: 550} {TRANSSPLICED} {Pfam: PH domain [PF17787.3, score=62.8]} {Human: ENSG00000101333, PLCB4, phospholipase C beta 4, [RH, Score=89.0, Expect=6e-24]} {Mouse: ENSMUSG00000039943, Plcb4, phospholipase C, beta 4, [Score=88.6, Expect=4e-21]} {Dmel: FBgn0262738, norpA, no receptor potential A, [Score=80.9, Expect=1e-18]} {Celegans: WBGene00001177, egl-8, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8, [Score=73.9, Expect=2e-16]} {Smed: dd_Smed_v6_3221_0_1, dd_Smed_v6_3221_0_1, [Score=144, Expect=6e-41]} {RNA1509_48109} {RNA1310_563.1} {RNA815_18946.1} |
62. | MligTC455_39086 | 622 | 12.97 | Mlig455_040374, Mlig455_050380 | Neo: - Age: - |
CEP164 | 1.8 | 0.950 | - | - | 0.850 | - | - | Mlig455_040374 {REF} {Length: 4167} {TRANSSPLICED} {Pfam: WW domain [PF00397.28, score=26.1]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [RH, Score=139, Expect=9e-33]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [RH, Score=129, Expect=4e-30]} {Dmel: FBgn0030716, CG9170, [RH, Score=88.6, Expect=1e-17]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [RH, Score=136, Expect=6e-33]} {RNA1509_24261} {RNA1310_3091.1, RNA1509_24261} {RNA1509_24261, RNA815_6934.1} Mlig455_050380 {REF} {Length: 4206} {TRANSSPLICED} {Pfam: WW domain [PF00397.28, score=26.0]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [RH, Score=139, Expect=1e-32]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [RH, Score=129, Expect=4e-30]} {Dmel: FBgn0030716, CG9170, [RH, Score=89.0, Expect=1e-17]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [RH, Score=138, Expect=2e-33]} {RNA1509_46898} {RNA1310_3091.1} {RNA815_6934.1} |
63. | MligTC455_45914 | 359 | 7.49 | Mlig455_025337 | Neo: - Age: logFC(26M/2M)=-0.269 |
TRAF3IP1 | 1.799 | - | - | 0.847 | - | - | 0.952 | Mlig455_025337 {REF} {Length: 2762} {TRANSSPLICED} {Pfam: Microtubule-binding protein MIP-T3 C-terminal region [PF17749.3, score=131.6]; Microtubule-binding protein MIP-T3 CH-like domain [PF10243.11, score=42.6]; Takusan [PF04822.15, score=19.2]} {Human: ENSG00000204104, TRAF3IP1, TRAF3 interacting protein 1, [Score=198, Expect=2e-55]} {Mouse: ENSMUSG00000034292, Traf3ip1, TRAF3 interacting protein 1, [RH, Score=189, Expect=2e-52]} {Dmel: FBgn0086707, ncm, nucampholin, [Score=48.9, Expect=1e-05]} {Celegans: WBGene00001127, dyf-11, [Score=67.4, Expect=1e-11]} {Smed: dd_Smed_v6_10562_0_1, dd_Smed_v6_10562_0_1, [Score=168, Expect=1e-45]} {RNA1509_5107} {RNA1310_14186.2} {RNA815_2859} |
64. | MligTC455_39331 | 404 | 8.42 | Mlig455_057236 | Neo: - Age: logFC(26M/2M)=-0.329 |
1.798 | 0.975 | - | - | - | 0.823 | - | Mlig455_057236 {REF} {Length: 2703} {RNA1509_28814} {RNA1310_9674} {RNA815_9245} | |
65. | MligTC455_51862 | 105 | 2.18 | Mlig455_022805 | Neo: - Age: - |
CLIP2 | 1.797 | - | - | 0.981 | - | - | 0.816 | Mlig455_022805 {REF} {Length: 3045} {TRANSSPLICED} {Pfam: CAP-Gly domain [PF01302.27, score=67.0]} {Human: ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=60.1, Expect=1e-08]; ENSG00000135837, CEP350, centrosomal protein 350, [Score=59.7, Expect=2e-08]; ENSG00000105270, CLIP3, CAP-Gly domain containing linker protein 3, [Score=59.3, Expect=2e-08]; ENSG00000130779, CLIP1, CAP-Gly domain containing linker protein 1, [Score=58.5, Expect=4e-08]} {Mouse: ENSMUSG00000013921, Clip3, CAP-GLY domain containing linker protein 3, [Score=59.3, Expect=1e-08]; ENSMUSG00000049550, Clip1, CAP-GLY domain containing linker protein 1, [Score=58.9, Expect=3e-08]; ENSMUSG00000063146, Clip2, CAP-GLY domain containing linker protein 2, [Score=58.5, Expect=3e-08]; ENSMUSG00000033671, Cep350, centrosomal protein 350, [Score=58.2, Expect=5e-08]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=62.0, Expect=2e-09]} {Smed: dd_Smed_v6_12415_0_1, dd_Smed_v6_12415_0_1, [Score=149, Expect=3e-40]} {RNA1509_11181} {RNA1310_5475} {RNA815_398} |
66. | MligTC455_47181 | 555 | 11.55 | Mlig455_012909, Mlig455_012919, Mlig455_039828 | Neo: - Age: - Region-enriched R2: 2.610/0.04973 |
1.796 | 0.977 | - | - | - | 0.819 | - | Mlig455_012909 {REF} {Length: 1504} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=48.7]} {Smed: dd_Smed_v6_9777_0_1, dd_Smed_v6_9777_0_1, [Score=161, Expect=3e-48]} {RNA1310_33903} {RNA815_16003} Mlig455_012919 {REF} {Length: 1506} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=48.0]} {Smed: dd_Smed_v6_9777_0_1, dd_Smed_v6_9777_0_1, [RH, Score=203, Expect=3e-63]} {RNA1310_33903} {RNA815_16003} Mlig455_039828 {REF} {Length: 1505} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=48.0]} {Smed: dd_Smed_v6_9777_0_1, dd_Smed_v6_9777_0_1, [RH, Score=203, Expect=3e-63]} {RNA1310_33903} {RNA815_16003} |
|
67. | MligTC455_18239 | 49 | 1.02 | Mlig455_005306 | Neo: - Age: - |
SSTR5 | 1.791 | - | - | 0.998 | - | 0.793 | - | Mlig455_005306 {REF} {Length: 1637} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=137.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=34.2]; Olfactory receptor [PF13853.8, score=25.8]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=22.6]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=21.2]} {Human: ENSG00000162009, SSTR5, somatostatin receptor 5, [Score=121, Expect=4e-30]; ENSG00000139874, SSTR1, somatostatin receptor 1, [Score=115, Expect=1e-27]} {Mouse: ENSMUSG00000037014, Sstr4, somatostatin receptor 4, [Score=120, Expect=1e-29]; ENSMUSG00000035431, Sstr1, somatostatin receptor 1, [Score=115, Expect=8e-28]; ENSMUSG00000047904, Sstr2, somatostatin receptor 2, [Score=115, Expect=3e-28]} {Dmel: FBgn0036789, AstC-R2, Allatostatin C receptor 2, [Score=132, Expect=4e-33]} {Celegans: WBGene00020086, npr-24, NeuroPeptide Receptor family, [Score=116, Expect=1e-28]} {Smed: dd_Smed_v6_16055_0_1, dd_Smed_v6_16055_0_1, [RH, Score=147, Expect=2e-40]} {RNA1310_89111} |
68. | MligTC455_40935 | 85 | 1.78 | Mlig455_059740 | Neo: - Age: Up-Down-Down |
SLC7A5 | 1.791 | - | - | 0.989 | - | - | 0.802 | Mlig455_059740 {REF} {Length: 4823} {Pfam: Amino acid permease [PF13520.8, score=182.1]; Amino acid permease [PF00324.23, score=97.0]} {Human: ENSG00000103257, SLC7A5, solute carrier family 7 member 5, [Score=377, Expect=8e-126]; ENSG00000155465, SLC7A7, solute carrier family 7 member 7, [Score=362, Expect=8e-120]} {Mouse: ENSMUSG00000040010, Slc7a5, solute carrier family 7 (cationic amino acid transporter, y+ system), member 5, [Score=377, Expect=8e-126]; ENSMUSG00000027737, Slc7a11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, [Score=376, Expect=1e-125]; ENSMUSG00000000958, Slc7a7, solute carrier family 7 (cationic amino acid transporter, y+ system), member 7, [Score=376, Expect=3e-125]} {Dmel: FBgn0039487, gb, genderblind, [RH, Score=385, Expect=5e-129]} {Celegans: WBGene00000004, aat-3, Amino Acid Transporter, [Score=347, Expect=1e-114]} {Smed: dd_Smed_v6_4211_0_1, dd_Smed_v6_4211_0_1, [RH, Score=495, Expect=5e-172]} {RNA1509_24986} {RNA1310_10698, RNA1509_24986} {RNA1509_24986, RNA815_4583} |
69. | MligTC455_29030 | 141 | 2.93 | Mlig455_061986 | Neo: - Age: logFC(26M/2M)=-0.349 Region-enriched R2: 5.117/0.03372 |
FZD5 | 1.789 | 0.975 | - | - | - | - | 0.814 | Mlig455_061986 {REF} {Length: 3701} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=386.1]; Fz domain [PF01392.24, score=95.9]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=582, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=586, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=545, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=388, Expect=7e-127]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [RH, Score=556, Expect=0.0]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1} |
70. | MligTC455_28498 | 3378 | 70.37 | Mlig455_056160, Mlig455_058741 | Neo: - |
NPHP1 | 1.788 | - | - | 0.963 | - | - | 0.825 | Mlig455_056160 {REF} {Length: 3355} {RNA1509_3623} {RNA1310_2702} {RNA815_1647} Mlig455_058741 {REF} {Length: 4029} {Pfam: SH3 domain [PF00018.30, score=32.1]; Variant SH3 domain [PF14604.8, score=31.1]; Variant SH3 domain [PF07653.19, score=31.0]} {Human: ENSG00000144061, NPHP1, nephrocystin 1, [RH, Score=227, Expect=2e-62]} {Mouse: ENSMUSG00000027378, Nphp1, nephronophthisis 1 (juvenile) homolog (human), [RH, Score=221, Expect=2e-60]} {Smed: dd_Smed_v6_9990_0_2, dd_Smed_v6_9990_0_2, [Score=211, Expect=4e-56]} {RNA1509_3623} {RNA1310_2702, RNA1509_3623} {RNA1509_3623, RNA815_1647} |
71. | MligTC455_40915 | 873 | 18.19 | Mlig455_042099 | Neo: - Age: - |
SLC22A24 | 1.787 | - | - | 0.951 | 0.836 | - | - | Mlig455_042099 {REF} {Length: 4000} {Pfam: Sugar (and other) transporter [PF00083.26, score=102.5]; Major Facilitator Superfamily [PF07690.18, score=76.5]} {Human: ENSG00000197658, SLC22A24, solute carrier family 22 member 24, [Score=119, Expect=2e-27]; ENSG00000197901, SLC22A6, solute carrier family 22 member 6, [Score=115, Expect=1e-26]} {Mouse: ENSMUSG00000023828, Slc22a3, solute carrier family 22 (organic cation transporter), member 3, [Score=121, Expect=1e-28]} {Dmel: FBgn0039178, CG6356, [Score=127, Expect=1e-30]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=125, Expect=5e-30]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=85.9, Expect=2e-17]} {RNA1509_14287, RNA1509_8510} {RNA1310_10700.1, RNA1509_14287, RNA1509_8510} {RNA1509_14287, RNA1509_8510, RNA815_2513} |
72. | MligTC455_44727 | 99 | 2.06 | Mlig455_033185 | Neo: - |
CLCN3 | 1.786 | 0.958 | - | - | - | 0.828 | - | Mlig455_033185 {REF} {Length: 4282} {TRANSSPLICED} {Pfam: Voltage gated chloride channel [PF00654.22, score=304.3]; CBS domain [PF00571.30, score=55.0]} {Human: ENSG00000109572, CLCN3, chloride voltage-gated channel 3, [Score=796, Expect=0.0]; ENSG00000073464, CLCN4, chloride voltage-gated channel 4, [Score=766, Expect=0.0]} {Mouse: ENSMUSG00000004319, Clcn3, chloride channel, voltage-sensitive 3, [Score=797, Expect=0.0]; ENSMUSG00000000605, Clcn4, chloride channel, voltage-sensitive 4, [Score=764, Expect=0.0]} {Dmel: FBgn0036566, ClC-c, Chloride channel-c, [Score=783, Expect=0.0]} {Celegans: WBGene00000532, clh-5, Chloride channel protein, [Score=676, Expect=0.0]} {Smed: dd_Smed_v6_4076_1_1, dd_Smed_v6_4076_1_1, [Score=729, Expect=0.0]} {RNA1509_27287} {RNA1310_201.1, RNA1509_27287} {RNA1509_27287, RNA815_6427.1} |
73. | MligTC455_43120 | 247 | 5.15 | Mlig455_025263 | Neo: - Age: Up-Down-Down |
1.784 | - | - | 0.950 | - | - | 0.834 | Mlig455_025263 {REF} {Length: 4290} {RNA1509_20151} {RNA1310_8688.1} {RNA815_9458.1} | |
74. | MligTC455_13927 | 79 | 1.65 | Mlig455_025242, Mlig455_025623 | Neo: - |
KIF1B | 1.783 | - | - | 0.993 | - | 0.790 | - | Mlig455_025242 {REF} {Length: 3364} {Pfam: FHA domain [PF00498.28, score=31.2]; Kinesin protein 1B [PF12423.10, score=29.5]} {Human: ENSG00000054523, KIF1B, kinesin family member 1B, [Score=52.4, Expect=2e-06]; ENSG00000197892, KIF13B, kinesin family member 13B, [Score=51.6, Expect=4e-06]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [Score=160, Expect=5e-41]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=58.2, Expect=2e-08]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [Score=210, Expect=2e-58]} {Smed: dd_Smed_v6_20223_0_1, dd_Smed_v6_20223_0_1, [Score=348, Expect=3e-110]} {RNA1310_9866} {RNA815_27415} Mlig455_025623 {REF} {Length: 4205} {Pfam: Kinesin motor domain [PF00225.25, score=345.1]; Microtubule binding [PF16796.7, score=70.6]; FHA domain [PF00498.28, score=30.2]; Kinesin-associated [PF16183.7, score=29.6]; Kinesin protein 1B [PF12423.10, score=28.9]} {Human: ENSG00000054523, KIF1B, kinesin family member 1B, [Score=464, Expect=6e-145]; ENSG00000130294, KIF1A, kinesin family member 1A, [Score=450, Expect=1e-135]; ENSG00000129250, KIF1C, kinesin family member 1C, [Score=448, Expect=2e-139]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [RH, Score=598, Expect=0.0]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=441, Expect=6e-132]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [Score=703, Expect=0.0]} {Smed: dd_Smed_v6_12573_0_1, dd_Smed_v6_12573_0_1, [Score=806, Expect=0.0]} {RNA1509_18998} {RNA1310_9866} {RNA815_31497} |
75. | MligTC455_41325 | 202 | 4.2 | Mlig455_025012 | Neo: - Age: Up-Down-Up |
CCDC151 | 1.779 | 0.975 | - | - | - | - | 0.804 | Mlig455_025012 {REF} {Length: 2382} {TRANSSPLICED} {Human: ENSG00000198003, CCDC151, coiled-coil domain containing 151, [Score=251, Expect=5e-75]} {Mouse: ENSMUSG00000039632, Ccdc151, coiled-coil domain containing 151, [Score=261, Expect=4e-79]} {Dmel: FBgn0036219, CCDC151, Coiled-coil domain containing protein 151, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_4526_0_1, dd_Smed_v6_4526_0_1, [Score=463, Expect=3e-158]} {RNA1509_18758} {RNA1310_9513.1} {RNA815_24234} |
76. | MligTC455_45944 | 75 | 1.57 | Mlig455_028968 | Neo: - Age: - |
NPR1 | 1.774 | 0.976 | - | - | - | - | 0.798 | Mlig455_028968 {REF} {Length: 2286} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=172.4]; Heme NO binding associated [PF07701.16, score=19.5]} {Human: ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=301, Expect=3e-95]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=297, Expect=4e-94]} {Mouse: ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=301, Expect=1e-95]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=299, Expect=2e-98]} {Dmel: FBgn0036368, CG10738, [Score=275, Expect=3e-85]} {Celegans: WBGene00020131, gcy-28, Receptor-type guanylate cyclase gcy-28, [Score=276, Expect=7e-86]} {Smed: dd_Smed_v6_7619_0_1, dd_Smed_v6_7619_0_1, [Score=325, Expect=2e-104]} {RNA1509_42903} {RNA1310_5627} {RNA815_1811} |
77. | MligTC455_09557 | 33 | 0.68 | Mlig455_059478 | Neo: - Age: Up-Down-Down |
B3GNT4 | 1.772 | 0.986 | - | - | - | 0.786 | - | Mlig455_059478 {REF} {Length: 2800} {Pfam: Galactosyltransferase [PF01762.23, score=72.9]} {Human: ENSG00000176383, B3GNT4, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, [Score=75.9, Expect=2e-14]} {Mouse: ENSMUSG00000074004, B3gnt6, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase), [Score=73.6, Expect=1e-13]} {Smed: dd_Smed_v6_9789_0_1, dd_Smed_v6_9789_0_1, [Score=110, Expect=5e-27]} {RNA1310_43488} |
78. | MligTC455_25135 | 288 | 6 | Mlig455_001749, Mlig455_001771 | Neo: - Age: - Region-enriched R2: 2.329/0.04280 |
P2RX4 | 1.772 | - | - | 0.965 | - | 0.807 | - | Mlig455_001749 {REF} {Length: 2951} {Pfam: ATP P2X receptor [PF00864.21, score=341.3]} {Human: ENSG00000135124, P2RX4, purinergic receptor P2X 4, [Score=247, Expect=3e-75]; ENSG00000187848, P2RX2, purinergic receptor P2X 2, [Score=235, Expect=5e-70]} {Mouse: ENSMUSG00000029470, P2rx4, purinergic receptor P2X, ligand-gated ion channel 4, [Score=248, Expect=1e-75]; ENSMUSG00000029503, P2rx2, purinergic receptor P2X, ligand-gated ion channel, 2, [Score=236, Expect=3e-70]} {Smed: dd_Smed_v6_10968_0_1, dd_Smed_v6_10968_0_1, [Score=316, Expect=7e-101]} {RNA1509_56054} {RNA1310_19416, RNA1509_56054} {RNA1509_56054, RNA815_42167} Mlig455_001771 {REF} {Length: 2484} {Pfam: ATP P2X receptor [PF00864.21, score=341.3]} {Human: ENSG00000135124, P2RX4, purinergic receptor P2X 4, [Score=247, Expect=3e-75]; ENSG00000187848, P2RX2, purinergic receptor P2X 2, [Score=235, Expect=5e-70]} {Mouse: ENSMUSG00000029470, P2rx4, purinergic receptor P2X, ligand-gated ion channel 4, [Score=248, Expect=1e-75]; ENSMUSG00000029503, P2rx2, purinergic receptor P2X, ligand-gated ion channel, 2, [Score=236, Expect=3e-70]} {Smed: dd_Smed_v6_10968_0_1, dd_Smed_v6_10968_0_1, [Score=316, Expect=7e-101]} {RNA1509_56054} {RNA1310_19416} {RNA815_42167} |
79. | MligTC455_28439 | 115 | 2.4 | Mlig455_059064, Mlig455_060465 | Neo: - Age: - |
1.766 | - | - | 0.992 | - | - | 0.774 | Mlig455_059064 {REF} {Length: 833} {NoTransDecoderORF} {RNA1509_43624} {RNA1310_9389.2} {RNA815_12646} Mlig455_060465 {REF} {Length: 320} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_43624} {RNA1310_18898} {RNA815_12646} |
|
80. | MligTC455_23314 | 139 | 2.9 | Mlig455_039680 | Neo: - Age: - |
CACNA2D2 | 1.765 | - | - | - | 0.807 | - | 0.958 | Mlig455_039680 {REF} {Length: 4498} {Pfam: VWA N-terminal [PF08399.13, score=89.9]; Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=86.3]; von Willebrand factor type A domain [PF13768.8, score=38.0]; von Willebrand factor type A domain [PF00092.30, score=36.1]; von Willebrand factor type A domain [PF13519.8, score=31.5]; Cache domain [PF02743.20, score=26.9]} {Human: ENSG00000007402, CACNA2D2, calcium voltage-gated channel auxiliary subunit alpha2delta 2, [RH, Score=340, Expect=6e-98]; ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [RH, Score=328, Expect=3e-94]} {Mouse: ENSMUSG00000010066, Cacna2d2, calcium channel, voltage-dependent, alpha 2/delta subunit 2, [RH, Score=338, Expect=1e-97]; ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [RH, Score=330, Expect=4e-95]} {Dmel: FBgn0028863, CG4587, [RH, Score=234, Expect=2e-62]} {Celegans: WBGene00007041, tag-180, [RH, Score=169, Expect=3e-42]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [Score=155, Expect=5e-38]} {RNA1509_48733} {RNA1310_3844, RNA1509_48733} {RNA1509_48733, RNA815_18071} |
81. | MligTC455_29051 | 484 | 10.08 | Mlig455_064767 | Neo: - Age: - |
TMEM30A | 1.764 | 0.953 | - | - | - | 0.811 | - | Mlig455_064767 {REF} {Length: 2581} {TRANSSPLICED} {Pfam: LEM3 (ligand-effect modulator 3) family / CDC50 family [PF03381.17, score=265.5]} {Human: ENSG00000112697, TMEM30A, transmembrane protein 30A, [RH, Score=234, Expect=7e-73]} {Mouse: ENSMUSG00000032328, Tmem30a, transmembrane protein 30A, [RH, Score=241, Expect=6e-76]} {Dmel: FBgn0030752, CG9947, [RH, Score=294, Expect=8e-97]} {Celegans: WBGene00019946, chat-1, CDC50 family protein chat-1, [Score=246, Expect=3e-78]} {Smed: dd_Smed_v6_6430_0_1, dd_Smed_v6_6430_0_1, [Score=274, Expect=3e-89]} {RNA1509_38539, RNA1509_38955} {RNA1310_9371, RNA1509_38539, RNA1509_38955} {RNA1509_38539, RNA1509_38955, RNA815_12157} |
82. | MligTC455_20719 | 173 | 3.61 | Mlig455_034915 | Neo: - Age: - |
SKIL | 1.763 | - | - | 0.982 | - | - | 0.781 | Mlig455_034915 {REF} {Length: 4545} {Pfam: SKI/SNO/DAC family [PF02437.19, score=103.5]; c-SKI Smad4 binding domain [PF08782.12, score=103.1]} {Human: ENSG00000136603, SKIL, SKI like proto-oncogene, [RH, Score=197, Expect=1e-53]; ENSG00000157933, SKI, SKI proto-oncogene, [RH, Score=192, Expect=2e-51]} {Mouse: ENSMUSG00000027660, Skil, SKI-like, [RH, Score=197, Expect=6e-54]; ENSMUSG00000029050, Ski, ski sarcoma viral oncogene homolog (avian), [RH, Score=194, Expect=1e-52]} {Dmel: FBgn0085450, Snoo, Sno oncogene, [RH, Score=183, Expect=4e-48]} {Smed: dd_Smed_v6_10921_0_1, dd_Smed_v6_10921_0_1, [RH, Score=153, Expect=8e-40]} {RNA1509_57419} {RNA1310_5927, RNA1509_57419} {RNA1509_57419, RNA815_17262} |
83. | MligTC455_50734 | 175 | 3.66 | Mlig455_044294 | Neo: - Age: Down-Up-Up Region-enriched R2: 4.054/0.00263 |
CHRNA3 | 1.761 | 0.988 | - | - | - | 0.773 | - | Mlig455_044294 {REF} {Length: 1830} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=242.4]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=225.5]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=373, Expect=1e-123]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=365, Expect=1e-120]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=360, Expect=9e-119]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=358, Expect=6e-118]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=376, Expect=3e-125]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=374, Expect=4e-124]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=450, Expect=4e-154]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=381, Expect=2e-127]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [RH, Score=651, Expect=0.0]} {RNA1509_45903} {RNA1310_14580} {RNA815_10044.1} |
84. | MligTC455_15506 | 219 | 4.57 | Mlig455_025204 | Neo: - Age: logFC(26M/2M)=-0.337 |
ANKEF1 | 1.758 | - | - | 0.980 | 0.778 | - | - | Mlig455_025204 {REF} {Length: 2950} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=181.3]; Ankyrin repeats (many copies) [PF13637.8, score=145.9]; Ankyrin repeats (many copies) [PF13857.8, score=133.7]; Ankyrin repeat [PF00023.32, score=131.5]; Ankyrin repeat [PF13606.8, score=130.5]} {Human: ENSG00000132623, ANKEF1, ankyrin repeat and EF-hand domain containing 1, [RH, Score=531, Expect=7e-178]} {Mouse: ENSMUSG00000074771, Ankef1, ankyrin repeat and EF-hand domain containing 1, [RH, Score=543, Expect=0.0]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=123, Expect=2e-28]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=120, Expect=1e-27]} {Smed: dd_Smed_v6_12476_0_1, dd_Smed_v6_12476_0_1, [RH, Score=731, Expect=0.0]} {RNA1509_36316, RNA1509_7497} {RNA1310_7884.1, RNA1509_36316, RNA1509_7497} {RNA1509_36316, RNA1509_7497, RNA815_1782} |
85. | MligTC455_33880 | 65 | 1.35 | Mlig455_057597 | Neo: - Age: - |
GRIN2A | 1.758 | 0.980 | - | - | - | 0.778 | - | Mlig455_057597 {REF} {Length: 4580} {Pfam: Ligand-gated ion channel [PF00060.28, score=102.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=74.4]; Receptor family ligand binding region [PF01094.30, score=30.9]} {Human: ENSG00000183454, GRIN2A, glutamate ionotropic receptor NMDA type subunit 2A, [RH, Score=340, Expect=2e-96]; ENSG00000273079, GRIN2B, glutamate ionotropic receptor NMDA type subunit 2B, [RH, Score=335, Expect=8e-95]; ENSG00000105464, GRIN2D, glutamate ionotropic receptor NMDA type subunit 2D, [RH, Score=330, Expect=3e-93]} {Mouse: ENSMUSG00000059003, Grin2a, glutamate receptor, ionotropic, NMDA2A (epsilon 1), [RH, Score=342, Expect=4e-97]; ENSMUSG00000002771, Grin2d, glutamate receptor, ionotropic, NMDA2D (epsilon 4), [RH, Score=335, Expect=2e-95]; ENSMUSG00000030209, Grin2b, glutamate receptor, ionotropic, NMDA2B (epsilon 2), [RH, Score=335, Expect=9e-95]} {Dmel: FBgn0053513, Nmdar2, NMDA receptor 2, [RH, Score=534, Expect=7e-170]} {Celegans: WBGene00003775, nmr-2, NMDA class glutamate Receptor; NMDA-type ionotropic glutamate receptor NMR-2, [RH, Score=478, Expect=6e-150]} {Smed: dd_Smed_v6_11481_0_1, dd_Smed_v6_11481_0_1, [RH, Score=900, Expect=0.0]} {RNA1509_23999} {RNA1310_1305.1, RNA1509_23999} {RNA1509_23999, RNA815_19439} |
86. | MligTC455_23544 | 169 | 3.53 | Mlig455_021925 | Neo: - Age: Up-Down-Down Region-enriched R2: 3.394/0.00033 |
DDR2 | 1.756 | - | - | 0.954 | - | 0.802 | - | Mlig455_021925 {REF} {Length: 4813} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=205.5]; Protein kinase domain [PF00069.27, score=103.7]; F5/8 type C domain [PF00754.27, score=57.5]} {Human: ENSG00000162733, DDR2, discoidin domain receptor tyrosine kinase 2, [Score=249, Expect=1e-68]} {Mouse: ENSMUSG00000026674, Ddr2, discoidin domain receptor family, member 2, [Score=251, Expect=1e-69]} {Dmel: FBgn0053531, Ddr, Discoidin domain receptor, [Score=238, Expect=3e-64]} {Celegans: WBGene00017381, svh-4, Discoidin domain-containing receptor tyrosine kinase B, [Score=176, Expect=3e-45]} {Smed: dd_Smed_v6_22332_0_1, dd_Smed_v6_22332_0_1, [Score=187, Expect=2e-48]} {RNA1509_46581} {RNA1310_21361} {RNA815_21661} |
87. | MligTC455_39561 | 102 | 2.12 | Mlig455_031901 | Neo: - Age: - |
1.756 | - | - | 0.985 | - | - | 0.771 | Mlig455_031901 {REF} {Length: 924} {NoTransDecoderORF} {RNA1509_55593} {RNA1310_40473} {RNA815_20507} | |
88. | MligTC455_33199 | 144 | 3 | Mlig455_068562 | Neo: - Age: - |
CAMKK2 | 1.754 | - | - | 0.983 | - | 0.771 | - | Mlig455_068562 {REF} {Length: 3078} {Pfam: Protein kinase domain [PF00069.27, score=209.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.7]; Kinase-like [PF14531.8, score=30.4]; Fungal protein kinase [PF17667.3, score=19.0]} {Human: ENSG00000110931, CAMKK2, calcium/calmodulin dependent protein kinase kinase 2, [RH, Score=417, Expect=4e-138]} {Mouse: ENSMUSG00000029471, Camkk2, calcium/calmodulin-dependent protein kinase kinase 2, beta, [RH, Score=409, Expect=4e-135]; ENSMUSG00000020785, Camkk1, calcium/calmodulin-dependent protein kinase kinase 1, alpha, [RH, Score=394, Expect=1e-129]} {Dmel: FBgn0040056, CG17698, [RH, Score=402, Expect=1e-130]} {Celegans: WBGene00000518, ckk-1, Calcium/calmodulin-dependent protein kinase kinase, [RH, Score=414, Expect=3e-137]} {Smed: dd_Smed_v6_18437_0_1, dd_Smed_v6_18437_0_1, [RH, Score=367, Expect=3e-118]} {RNA1509_51718} {RNA1310_7593.1} {RNA815_7566} |
89. | MligTC455_41413 | 230 | 4.78 | Mlig455_039643 | Neo: - Age: - |
RBFOX1 | 1.753 | - | - | 0.972 | 0.781 | - | - | Mlig455_039643 {REF} {Length: 2417} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=65.4]} {Human: ENSG00000078328, RBFOX1, RNA binding fox-1 homolog 1, [RH, Score=163, Expect=4e-48]; ENSG00000277564, RBFOX2, RNA binding fox-1 homolog 2, [RH, Score=162, Expect=6e-47]; ENSG00000167281, RBFOX3, RNA binding fox-1 homolog 3, [RH, Score=162, Expect=5e-47]; ENSG00000100320, RBFOX2, RNA binding fox-1 homolog 2, [RH, Score=162, Expect=6e-47]} {Mouse: ENSMUSG00000008658, Rbfox1, RNA binding protein, fox-1 homolog (C. elegans) 1, [RH, Score=163, Expect=3e-47]; ENSMUSG00000025576, Rbfox3, RNA binding protein, fox-1 homolog (C. elegans) 3, [RH, Score=163, Expect=5e-47]; ENSMUSG00000033565, Rbfox2, RNA binding protein, fox-1 homolog (C. elegans) 2, [RH, Score=162, Expect=8e-47]} {Dmel: FBgn0052062, Rbfox1, RNA-binding Fox protein 1, [RH, Score=159, Expect=2e-43]} {Celegans: WBGene00001484, fox-1, Sex determination protein fox-1, [RH, Score=132, Expect=2e-35]} {Smed: dd_Smed_v6_7213_0_1, dd_Smed_v6_7213_0_1, [RH, Score=166, Expect=5e-48]} {RNA1509_10779} {RNA1310_30138} {RNA815_36120} |
90. | MligTC455_20298 | 420 | 8.74 | Mlig455_019372, Mlig455_019594 | Neo: - Age: - Region-enriched R4: 1.730/0.04440 |
SLC17A5 | 1.748 | - | - | 0.952 | 0.796 | - | - | Mlig455_019372 {REF} {Length: 2931} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=144.7]; Uncharacterised MFS-type transporter YbfB [PF06779.16, score=26.7]; Sugar (and other) transporter [PF00083.26, score=20.2]} {Human: ENSG00000119899, SLC17A5, solute carrier family 17 member 5, [Score=186, Expect=2e-53]} {Mouse: ENSMUSG00000049624, Slc17a5, solute carrier family 17 (anion/sugar transporter), member 5, [Score=181, Expect=2e-51]} {Dmel: FBgn0038799, MFS9, Major Facilitator Superfamily Transporter 9, [Score=159, Expect=1e-43]} {Celegans: WBGene00022647, slc-17.1, SLC (SoLute Carrier) homolog, [Score=144, Expect=3e-38]} {Smed: dd_Smed_v6_6845_0_1, dd_Smed_v6_6845_0_1, [RH, Score=494, Expect=2e-174]} {RNA1509_39490} {RNA1310_17100} {RNA815_9623} Mlig455_019594 {REF} {Length: 2935} {Pfam: Major Facilitator Superfamily [PF07690.18, score=144.5]; Uncharacterised MFS-type transporter YbfB [PF06779.16, score=27.0]; Sugar (and other) transporter [PF00083.26, score=18.8]} {Human: ENSG00000119899, SLC17A5, solute carrier family 17 member 5, [Score=186, Expect=4e-53]} {Mouse: ENSMUSG00000049624, Slc17a5, solute carrier family 17 (anion/sugar transporter), member 5, [Score=181, Expect=2e-51]} {Dmel: FBgn0038799, MFS9, Major Facilitator Superfamily Transporter 9, [Score=159, Expect=2e-43]} {Celegans: WBGene00022647, slc-17.1, SLC (SoLute Carrier) homolog, [Score=144, Expect=5e-38]} {Smed: dd_Smed_v6_6845_0_1, dd_Smed_v6_6845_0_1, [RH, Score=493, Expect=7e-174]} {RNA1509_39490} {RNA1310_17100} {RNA815_9623} |
91. | MligTC455_37895 | 245 | 5.1 | Mlig455_050995 | Neo: - |
CBL | 1.747 | 0.959 | - | - | - | 0.788 | - | Mlig455_050995 {REF} {Length: 3237} {Pfam: CBL proto-oncogene N-terminus, EF hand-like domain [PF02761.16, score=73.2]; CBL proto-oncogene N-terminus, SH2-like domain [PF02762.16, score=38.5]; CBL proto-oncogene N-terminal domain 1 [PF02262.18, score=38.3]} {Human: ENSG00000110395, CBL, Cbl proto-oncogene, [Score=149, Expect=5e-37]; ENSG00000114423, CBLB, Cbl proto-oncogene B, [Score=144, Expect=3e-35]} {Mouse: ENSMUSG00000034342, Cbl, Casitas B-lineage lymphoma, [Score=149, Expect=3e-37]; ENSMUSG00000022637, Cblb, Casitas B-lineage lymphoma b, [Score=144, Expect=2e-35]} {Dmel: FBgn0020224, Cbl, Cbl proto-oncogene, [Score=141, Expect=5e-36]} {Celegans: WBGene00004829, sli-1, Sli-1 protein; Suppressor of LIneage defect, [Score=129, Expect=1e-31]} {Smed: dd_Smed_v6_330_0_1, dd_Smed_v6_330_0_1, [Score=141, Expect=2e-35]} {RNA1509_30011} {RNA1310_9554.1, RNA1509_30011} {RNA1509_30011, RNA815_22511} |
92. | MligTC455_14951 | 478 | 9.95 | Mlig455_032947 | Neo: - Age: - |
1.746 | 0.962 | - | 0.784 | - | - | - | Mlig455_032947 {REF} {Length: 1296} {Pfam: PTN/MK heparin-binding protein family, C-terminal domain [PF01091.20, score=25.6]; PTN/MK heparin-binding protein family, N-terminal domain [PF05196.15, score=24.8]; Spondin-like TSP1 domain [PF19028.2, score=20.3]} {RNA1509_34845} {RNA1310_26331.1, RNA1509_34845} {RNA1509_34845, RNA815_23523} | |
93. | MligTC455_43034 | 470 | 9.79 | Mlig455_009703 | Neo: - Age: - |
1.744 | - | - | 0.956 | - | - | 0.788 | Mlig455_009703 {REF} {Length: 4741} {Pfam: NHL repeat [PF01436.23, score=34.6]} {Dmel: FBgn0265356, tn, thin, [Score=53.9, Expect=2e-07]} {RNA1509_22989} {RNA1310_8201.1, RNA1509_22989} {RNA1509_22989, RNA815_27967} | |
94. | MligTC455_34420 | 572 | 11.92 | Mlig455_068596 | Neo: - |
ANK3 | 1.742 | - | - | - | - | 0.950 | 0.792 | Mlig455_068596 {REF} {Length: 3030} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=124.1]; Ankyrin repeats (many copies) [PF13637.8, score=105.9]; Ankyrin repeat [PF13606.8, score=89.2]; Ankyrin repeat [PF00023.32, score=80.3]; Ankyrin repeats (many copies) [PF13857.8, score=73.6]; Calponin homology (CH) domain [PF00307.33, score=24.8]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=114, Expect=1e-24]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=113, Expect=8e-25]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=116, Expect=9e-26]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=101, Expect=2e-21]} {Smed: dd_Smed_v6_10986_0_1, dd_Smed_v6_10986_0_1, [RH, Score=650, Expect=0.0]} {RNA1509_4310} {RNA1310_3592.1} {RNA815_588} |
95. | MligTC455_30365 | 335 | 6.99 | Mlig455_005426 | Neo: - Age: - |
C20orf194 | 1.741 | 0.969 | - | - | - | 0.772 | - | Mlig455_005426 {REF} {Length: 2028} {TRANSSPLICED} {Human: ENSG00000088854, C20orf194, chromosome 20 open reading frame 194, [Score=100, Expect=2e-21]} {Mouse: ENSMUSG00000027309, 4930402H24Rik, RIKEN cDNA 4930402H24 gene, [RH, Score=108, Expect=4e-24]} {Smed: dd_Smed_v6_10121_0_1, dd_Smed_v6_10121_0_1, [Score=88.2, Expect=5e-18]} {RNA1509_29925} {RNA1310_1263.1} {RNA815_15442} |
96. | MligTC455_20418 | 213 | 4.45 | Mlig455_003920 | Neo: - Age: - |
1.74 | 0.959 | - | - | 0.781 | - | - | Mlig455_003920 {REF} {Length: 3500} {Pfam: Ring finger domain [PF13639.8, score=19.8]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=18.9]} {RNA1509_20350, RNA1509_23231} {RNA1310_6875, RNA1509_20350, RNA1509_23231} {RNA1509_20350, RNA1509_23231, RNA815_2399.1} | |
97. | MligTC455_22088 | 35 | 0.73 | Mlig455_049477 | Neo: - Age: logFC(26M/2M)=-0.423 |
1.74 | - | - | - | 0.790 | - | 0.950 | Mlig455_049477 {REF} {Length: 3606} {TRANSSPLICED} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=109.4]; WSC domain [PF01822.21, score=26.7]} {Celegans: WBGene00003174, mec-10, Degenerin mec-10, [Score=55.5, Expect=2e-07]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [Score=60.1, Expect=5e-09]} {RNA1509_30712} {RNA1310_3752.1} {RNA815_1359} | |
98. | MligTC455_41430 | 65 | 1.35 | Mlig455_070915 | Neo: - Age: - |
BHLHE22 | 1.738 | - | - | 0.982 | - | 0.756 | - | Mlig455_070915 {REF} {Length: 1052} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=58.4]} {Human: ENSG00000180828, BHLHE22, basic helix-loop-helix family member e22, [RH, Score=135, Expect=4e-37]} {Mouse: ENSMUSG00000025128, Bhlhe22, basic helix-loop-helix family, member e22, [RH, Score=133, Expect=8e-37]; ENSMUSG00000045493, Bhlhe23, basic helix-loop-helix family, member e23, [RH, Score=129, Expect=1e-36]} {Dmel: FBgn0032651, Oli, Olig family, [RH, Score=135, Expect=4e-39]} {Celegans: WBGene00001961, hlh-17, Helix Loop Helix, [RH, Score=103, Expect=2e-28]} {Smed: dd_Smed_v6_12722_0_1, dd_Smed_v6_12722_0_1, [RH, Score=129, Expect=2e-37]} {RNA1310_107478} |
99. | MligTC455_25560 | 853 | 17.77 | Mlig455_039961, Mlig455_039974 | Neo: - Age: - |
SLC2A3, SLC2A6 | 1.736 | 0.779 | - | 0.957 | - | - | - | Mlig455_039961 {REF} {Length: 2890} {TRANSSPLICED} {Pfam: Sugar (and other) transporter [PF00083.26, score=316.5]; Major Facilitator Superfamily [PF07690.18, score=90.3]; Fungal trichothecene efflux pump (TRI12) [PF06609.15, score=17.2]} {Human: ENSG00000281165, SLC2A6, solute carrier family 2 member 6, [RH, Score=218, Expect=4e-64]; ENSG00000160326, SLC2A6, solute carrier family 2 member 6, [RH, Score=218, Expect=4e-64]; ENSG00000136856, SLC2A8, solute carrier family 2 member 8, [RH, Score=209, Expect=3e-61]} {Mouse: ENSMUSG00000026791, Slc2a8, solute carrier family 2, (facilitated glucose transporter), member 8, [Score=214, Expect=5e-63]} {Dmel: FBgn0033644, Tret1-2, Trehalose transporter 1-2, [RH, Score=216, Expect=7e-64]} {Celegans: WBGene00019207, fgt-1, Facilitated glucose transporter protein 1, [Score=160, Expect=2e-43]} {Smed: dd_Smed_v6_2995_0_1, dd_Smed_v6_2995_0_1, [RH, Score=268, Expect=3e-84]} {RNA1509_17471, RNA1509_33131} {RNA1310_17649, RNA1509_17471, RNA1509_33131} {RNA1509_17471, RNA1509_33131, RNA815_11064.1} Mlig455_039974 {REF} {Length: 3466} {TRANSSPLICED} {Pfam: Sugar (and other) transporter [PF00083.26, score=137.0]; Major Facilitator Superfamily [PF07690.18, score=64.6]; Fungal trichothecene efflux pump (TRI12) [PF06609.15, score=18.7]} {Human: ENSG00000059804, SLC2A3, solute carrier family 2 member 3, [Score=103, Expect=5e-24]} {Mouse: ENSMUSG00000003153, Slc2a3, solute carrier family 2 (facilitated glucose transporter), member 3, [Score=96.3, Expect=1e-21]; ENSMUSG00000028645, Slc2a1, solute carrier family 2 (facilitated glucose transporter), member 1, [Score=94.4, Expect=5e-21]; ENSMUSG00000037490, Slc2a12, solute carrier family 2 (facilitated glucose transporter), member 12, [Score=92.0, Expect=5e-20]} {Dmel: FBgn0033644, Tret1-2, Trehalose transporter 1-2, [Score=91.7, Expect=4e-20]} {Smed: dd_Smed_v6_2995_0_1, dd_Smed_v6_2995_0_1, [Score=154, Expect=5e-43]} {RNA1509_17471, RNA1509_45587} {RNA1310_17649, RNA1509_45587} {RNA1509_45587, RNA815_11064.1} |
100. | MligTC455_29449 | 88 | 1.84 | Mlig455_055134 | Neo: - Age: Up-Down-Down Region-enriched R4: 2.118/0.04706 |
1.733 | - | - | 0.986 | - | - | 0.747 | Mlig455_055134 {REF} {Length: 3438} {Smed: dd_Smed_v6_15433_0_1, dd_Smed_v6_15433_0_1, [Score=42.7, Expect=8e-06]} {RNA1509_50401} {RNA1310_13609} {RNA815_5685.1} |