Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_41636 | 50 | 1.04 | Mlig455_000765 | Neo: - Age: - |
Mlig455_000765 {REF} {Length: 727} {RNA1310_64301} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -3.797 | 0.978 | 1.00000 | 1.00000 | |
RegionR2 | 0.484 | 0.978 | 0.51649 | 0.89205 | |
RegionR3 | 1.754 | 0.978 | 0.08212 | 0.50687 | |
RegionR4 | 0.592 | 0.978 | 0.51630 | 0.84191 | |
RegionR5 | -2.079 | 0.978 | 1.00000 | 1.00000 | |
RegionR6 | -0.171 | 0.978 | 0.73694 | 1.00000 | |
RegionR7 | 1.147 | 0.978 | 0.35785 | 0.99418 | |
RegionR8 | 2.071 | 0.978 | 0.19851 | 0.79542 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.265 | 0.978 | 1.00000 | 1.00000 | |
RegenerationR2 | -0.413 | 0.978 | 0.68481 | 0.95061 | |
RegenerationR3 | -0.37 | 0.978 | 0.69462 | 0.94572 | |
RegenerationR4 | -1.851 | 0.978 | 0.23037 | 0.67940 | |
RegenerationR5 | 0.445 | 0.978 | 0.41530 | 0.80863 | |
RegenerationR6 | -1.066 | 0.978 | 0.56318 | 0.84757 | |
RegenerationBL | -4.209 | 0.978 | 0.11566 | 0.40239 | |
RegenerationTP | 0.223 | 0.978 | 0.91504 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_41636 | 50 | 1.04 | Mlig455_000765 | Neo: - Age: - |
4 | - | - | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_000765 {REF} {Length: 727} {RNA1310_64301} | |
2. | MligTC455_52544 | 250 | 5.21 | Mlig455_030562 | Neo: - Age: Up-Down-Down Region-enriched R8: 3.544/0.00108 |
2.695 | - | - | 0.969 | - | 0.834 | 0.892 | Mlig455_030562 {REF} {Length: 1251} {RNA1310_32103} {RNA815_22028} | |
3. | MligTC455_38826 | 244 | 5.08 | Mlig455_059316 | Neo: - Age: Up-Down-Up Region-enriched R8: 3.511/0.00478 |
RDX | 1.934 | - | - | 0.957 | - | - | 0.977 | Mlig455_059316 {REF} {Length: 3395} {Pfam: Ezrin/radixin/moesin family [PF00769.21, score=106.5]; FERM C-terminal PH-like domain [PF09380.12, score=87.8]; FERM central domain [PF00373.20, score=83.0]; FERM N-terminal domain [PF09379.12, score=66.5]} {Human: ENSG00000137710, RDX, radixin, [RH, Score=589, Expect=0.0]; ENSG00000092820, EZR, ezrin, [RH, Score=577, Expect=0.0]; ENSG00000147065, MSN, moesin, [RH, Score=561, Expect=0.0]} {Mouse: ENSMUSG00000032050, Rdx, radixin, [RH, Score=586, Expect=0.0]; ENSMUSG00000031207, Msn, moesin, [RH, Score=557, Expect=0.0]} {Dmel: FBgn0011661, Moe, Moesin, [RH, Score=514, Expect=5e-174]} {Celegans: WBGene00001333, erm-1, ERM-1B; Ezrin/Radixin/Moesin, [Score=545, Expect=0.0]} {Smed: dd_Smed_v6_8101_0_1, dd_Smed_v6_8101_0_1, [Score=504, Expect=7e-172]} {RNA1509_50666} {RNA1310_19690} {RNA815_6880} |
4. | MligTC455_23946 | 219 | 4.57 | Mlig455_044344 | Neo: - Age: - Region-enriched R8: 3.871/0.00002 Regeneration-downregulated BL: -7.362 Regeneration-depleted BL: -7.362 |
1.932 | - | - | 0.984 | - | - | 0.948 | Mlig455_044344 {REF} {Length: 1011} {RNA1509_17939} {RNA1310_36650.1} {RNA815_9418.1} | |
5. | MligTC455_54115 | 1122 | 23.38 | Mlig455_046735, Mlig455_046741, Mlig455_046761, Mlig455_046824 | Neo: - Age: Up-Down-Down Region-specific R8: 6.242 Region-enriched R8: 6.213/0.00000 Regeneration-downregulated BL: -5.695 Regeneration-depleted BL: -5.695 |
AVIL, VIL1 | 1.917 | - | - | 0.973 | - | - | 0.944 | Mlig455_046735 {REF} {Length: 3237} {TRANSSPLICED} {Pfam: Gelsolin repeat [PF00626.24, score=254.9]; Villin headpiece domain [PF02209.21, score=62.4]} {Human: ENSG00000135407, AVIL, advillin, [RH, Score=668, Expect=0.0]; ENSG00000127831, VIL1, villin 1, [RH, Score=656, Expect=0.0]} {Mouse: ENSMUSG00000025432, Avil, advillin, [RH, Score=655, Expect=0.0]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=339, Expect=4e-104]} {Celegans: WBGene00001443, fli-1, Protein flightless-1 homolog, [Score=157, Expect=3e-39]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [Score=157, Expect=4e-42]} {RNA1509_17120} {RNA1310_1438.1} {RNA815_2416.1} Mlig455_046741 {REF} {Length: 3667} {Pfam: Gelsolin repeat [PF00626.24, score=257.0]; Villin headpiece domain [PF02209.21, score=62.3]} {Human: ENSG00000135407, AVIL, advillin, [RH, Score=690, Expect=0.0]; ENSG00000127831, VIL1, villin 1, [RH, Score=675, Expect=0.0]} {Mouse: ENSMUSG00000025432, Avil, advillin, [RH, Score=681, Expect=0.0]; ENSMUSG00000026175, Vil1, villin 1, [RH, Score=652, Expect=0.0]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=362, Expect=4e-113]} {Celegans: WBGene00010593, gsnl-1, Gelsolin-like protein 1, [Score=196, Expect=2e-54]} {Smed: dd_Smed_v6_929_0_1, dd_Smed_v6_929_0_1, [Score=179, Expect=1e-49]} {RNA1509_17120} {RNA1310_1438.1} {RNA815_5185} Mlig455_046761 {REF} {Length: 1969} {Pfam: Gelsolin repeat [PF00626.24, score=108.4]; Villin headpiece domain [PF02209.21, score=61.9]} {Human: ENSG00000127831, VIL1, villin 1, [Score=389, Expect=1e-130]; ENSG00000135407, AVIL, advillin, [Score=378, Expect=7e-123]} {Mouse: ENSMUSG00000026175, Vil1, villin 1, [Score=375, Expect=1e-121]; ENSMUSG00000025432, Avil, advillin, [Score=359, Expect=1e-115]} {Dmel: FBgn0003187, qua, quail, [Score=169, Expect=3e-45]} {Celegans: WBGene00010593, gsnl-1, Gelsolin-like protein 1, [Score=102, Expect=2e-23]} {Smed: dd_Smed_v6_1673_0_1, dd_Smed_v6_1673_0_1, [Score=104, Expect=2e-24]} {RNA1509_17120} {RNA1310_1438.1} {RNA815_2416.1} Mlig455_046824 {REF} {Length: 3159} {Pfam: Gelsolin repeat [PF00626.24, score=257.2]; Villin headpiece domain [PF02209.21, score=63.9]} {Human: ENSG00000135407, AVIL, advillin, [RH, Score=691, Expect=0.0]; ENSG00000127831, VIL1, villin 1, [RH, Score=674, Expect=0.0]} {Mouse: ENSMUSG00000025432, Avil, advillin, [RH, Score=682, Expect=0.0]; ENSMUSG00000026175, Vil1, villin 1, [RH, Score=652, Expect=0.0]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=365, Expect=3e-114]} {Celegans: WBGene00010593, gsnl-1, Gelsolin-like protein 1, [Score=192, Expect=3e-53]} {Smed: dd_Smed_v6_929_0_1, dd_Smed_v6_929_0_1, [Score=179, Expect=1e-49]} {RNA1509_17120} {RNA1310_1438.1} {RNA815_5185} |
6. | MligTC455_14757 | 726 | 15.12 | Mlig455_043399, Mlig455_043416, Mlig455_043559, Mlig455_043567 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-0.347 Region-specific R8: 6.849 Region-enriched R8: 6.705/0.00000 Regeneration-downregulated BL: -8.524 Regeneration-depleted BL: -8.524 |
1.916 | - | - | 0.946 | - | - | 0.970 | Mlig455_043399 {REF} {Length: 5997} {Dmel: FBgn0010434, cora, coracle, [Score=80.5, Expect=1e-14]} {RNA1509_17394} {RNA1310_20597} {RNA815_24724} Mlig455_043416 {REF} {Length: 6138} {RNA1509_17394} {RNA1310_20597} {RNA815_24724} Mlig455_043559 {REF} {Length: 7159} {RNA1509_17394} {RNA1310_38694} {RNA815_21047} Mlig455_043567 {REF} {Length: 8454} {Dmel: FBgn0010434, cora, coracle, [Score=51.6, Expect=3e-06]} {RNA1509_17394} {RNA1310_20597} {RNA815_24724} |
|
7. | MligTC455_41192 | 356 | 7.42 | Mlig455_007850, Mlig455_007862 | Neo: - Age: - Region-enriched R8: 6.065/0.01332 |
1.914 | - | - | 0.950 | - | - | 0.964 | Mlig455_007850 {REF} {Length: 1184} {RNA1310_28844} {RNA815_36557} Mlig455_007862 {REF} {Length: 1113} {RNA1310_28844} {RNA815_36557} |
|
8. | MligTC455_03038 | 227 | 4.72 | Mlig455_060778 | Neo: - Age: Down-Up-Down Region-enriched R8: 6.261/0.00000 |
1.911 | - | - | 0.956 | - | - | 0.955 | Mlig455_060778 {REF} {Length: 4155} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=27.8} {Mouse: ENSMUSG00000059854, Hydin, HYDIN, axonemal central pair apparatus protein, [Score=55.1, Expect=5e-07]} {RNA1509_16236} {RNA1310_4008} {RNA815_2550} | |
9. | MligTC455_06772 | 238 | 4.96 | Mlig455_048772 | Neo: - Age: - Region-enriched R8: 6.268/0.00000 |
1.91 | - | - | 0.947 | - | - | 0.963 | Mlig455_048772 {REF} {Length: 839} {RNA1310_24767.2} {RNA815_33473} | |
10. | MligTC455_36215 | 359 | 7.47 | Mlig455_060878 | Neo: - Age: - Region-enriched R8: 8.367/0.00000 |
PLG | 1.909 | - | - | 0.951 | - | - | 0.958 | Mlig455_060878 {REF} {Length: 5184} {Pfam: Kringle domain [PF00051.20, score=232.3]} {Human: ENSG00000122194, PLG, plasminogen, [Score=147, Expect=7e-36]} {Mouse: ENSMUSG00000059481, Plg, plasminogen, [Score=157, Expect=3e-39]} {Dmel: FBgn0020391, Nrk, Neurospecific receptor kinase, [Score=67.0, Expect=6e-11]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=66.2, Expect=7e-11]} {Smed: dd_Smed_v6_9220_0_1, dd_Smed_v6_9220_0_1, [RH, Score=247, Expect=5e-68]} {RNA1509_32537} {RNA1310_4321.1} {RNA815_8153} |
11. | MligTC455_06773 | 251 | 5.23 | Mlig455_069732 | Neo: - Age: Down-Up-Down |
1.905 | - | - | 0.946 | - | - | 0.959 | Mlig455_069732 {REF} {Length: 1347} {RNA1310_24767.1} {RNA815_33473} | |
12. | MligTC455_51672 | 157 | 3.26 | Mlig455_014666 | Neo: - Age: - Region-enriched R8: 5.800/0.00000 |
MEP1B | 1.904 | - | - | 0.950 | - | - | 0.954 | Mlig455_014666 {REF} {Length: 1216} {Pfam: Astacin (Peptidase family M12A) [PF01400.26, score=143.8]} {Human: ENSG00000141434, MEP1B, meprin A subunit beta, [Score=103, Expect=4e-24]} {Mouse: ENSMUSG00000024313, Mep1b, meprin 1 beta, [Score=107, Expect=2e-25]} {Dmel: FBgn0028950, CG15255, [Score=111, Expect=1e-28]} {Celegans: WBGene00003534, nas-15, Zinc metalloproteinase nas-15, [RH, Score=122, Expect=4e-31]} {Smed: dd_Smed_v6_85_0_1, dd_Smed_v6_85_0_1, [Score=120, Expect=2e-32]} {RNA1310_41083} {RNA815_28844} |
13. | MligTC455_53694 | 2501 | 52.09 | Mlig455_003991 | Neo: - Age: Down-Up-Up Region-enriched R8: 7.080/0.00000 |
CAV1 | 1.904 | - | - | 0.950 | - | - | 0.954 | Mlig455_003991 {REF} {Length: 3303} {TRANSSPLICED} {Pfam: Caveolin [PF01146.19, score=127.7]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=102, Expect=1e-27]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=103, Expect=4e-28]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=78.6, Expect=3e-18]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=146, Expect=5e-46]} {RNA1509_19152} {RNA1310_47545} {RNA815_23829} |
14. | MligTC455_53695 | 2490 | 51.88 | Mlig455_004074 | Neo: - Age: - Region-enriched R8: 7.100/0.00000 |
CAV1 | 1.903 | - | - | 0.950 | - | - | 0.953 | Mlig455_004074 {REF} {Length: 808} {Pfam: Caveolin [PF01146.19, score=127.7]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=102, Expect=1e-27]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=103, Expect=4e-28]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=78.6, Expect=3e-18]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=146, Expect=5e-46]} {RNA1509_19152} {RNA1310_47545, RNA1509_19152} {RNA1509_19152, RNA815_23829} |
15. | MligTC455_06906 | 1854 | 38.62 | Mlig455_010761 | Neo: - Age: Down-Up-Up Region-specific R8: 8.047 Region-enriched R8: 7.100/0.00000 |
1.899 | - | - | 0.945 | - | - | 0.954 | Mlig455_010761 {REF} {Length: 812} {RNA1509_21716} {RNA1310_48870, RNA1509_21716} {RNA1509_21716, RNA815_12215.2} | |
16. | MligTC455_31518 | 19118 | 398.29 | Mlig455_053864, Mlig455_053878 | Neo: - Age: Down-Down-Up, logFC(26M/2M)=2.053 Region-enriched R8: 7.674/0.00000 |
PI16 | 1.895 | - | - | 0.950 | - | - | 0.945 | Mlig455_053864 {REF} {Length: 1794} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=56.1]; Kringle domain [PF00051.20, score=52.3]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=100, Expect=1e-22]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [Score=99.0, Expect=3e-22]} {Dmel: FBgn0038126, CG8483, [Score=102, Expect=1e-23]} {Celegans: WBGene00011724, scl-18, SCP-Like extracellular protein, [RH, Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_924_0_1, dd_Smed_v6_924_0_1, [RH, Score=128, Expect=3e-35]} {RNA1509_603} {RNA1310_25676} {RNA815_7928} Mlig455_053878 {REF} {Length: 1368} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=56.1]; Kringle domain [PF00051.20, score=52.3]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=100, Expect=1e-22]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [Score=99.0, Expect=3e-22]} {Dmel: FBgn0038126, CG8483, [Score=102, Expect=1e-23]} {Celegans: WBGene00011724, scl-18, SCP-Like extracellular protein, [RH, Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_924_0_1, dd_Smed_v6_924_0_1, [RH, Score=128, Expect=3e-35]} {RNA1509_603} {RNA1310_25676} {RNA815_7928} |
17. | MligTC455_31519 | 9556 | 199.07 | Mlig455_055347 | Neo: - Age: Down-Down-Up, logFC(26M/2M)=-0.365 Region-enriched R8: 7.870/0.00000 |
PI16 | 1.895 | - | - | 0.950 | - | - | 0.945 | Mlig455_055347 {REF} {Length: 1681} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=56.5]; Kringle domain [PF00051.20, score=52.7]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=84.3, Expect=2e-17]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [Score=82.4, Expect=6e-17]} {Dmel: FBgn0038126, CG8483, [Score=97.4, Expect=2e-22]} {Celegans: WBGene00003055, lon-1, LONg, [Score=65.1, Expect=9e-12]} {Smed: dd_Smed_v6_433_0_1, dd_Smed_v6_433_0_1, [Score=111, Expect=3e-29]} {RNA1509_603} {RNA1310_25676} {RNA815_7928} |
18. | MligTC455_09671 | 844 | 17.59 | Mlig455_014682 | Neo: - Age: Down-Up-Down Region-specific R8: 8.130 Region-enriched R8: 7.655/0.00000 |
1.894 | - | - | 0.941 | - | - | 0.953 | Mlig455_014682 {REF} {Length: 1122} {Pfam: PMP-22/EMP/MP20/Claudin tight junction [PF13903.8, score=18.5]} {RNA1509_51461} {RNA1310_45054.1, RNA1509_51461} {RNA1509_51461, RNA815_17340} | |
19. | MligTC455_31520 | 9547 | 198.9 | Mlig455_055402 | Neo: - Age: logFC(26M/2M)=-0.427 Region-enriched R8: 7.718/0.00000 |
PI16 | 1.894 | - | - | 0.950 | - | - | 0.944 | Mlig455_055402 {REF} {Length: 1363} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=27.4]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=69.3, Expect=4e-13]; ENSG00000173401, GLIPR1L1, GLIPR1 like 1, [Score=67.8, Expect=4e-13]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [Score=71.2, Expect=7e-14]} {Dmel: FBgn0038126, CG8483, [Score=55.8, Expect=6e-09]} {Celegans: WBGene00009890, scl-9, SCP-Like extracellular protein, [Score=50.4, Expect=1e-07]} {Smed: dd_Smed_v6_924_0_2, dd_Smed_v6_924_0_2, [Score=87.0, Expect=1e-21]} {RNA1509_603} {RNA1310_25676} {RNA815_7928} |
20. | MligTC455_13746 | 200 | 4.17 | Mlig455_064975, Mlig455_066810 | Neo: - Age: - Region-enriched R8: 8.067/0.00000 |
1.892 | - | - | 0.937 | - | - | 0.955 | Mlig455_064975 {REF} {Length: 2922} {RNA1509_22976} {RNA1310_9502} {RNA815_8881} Mlig455_066810 {REF} {Length: 2922} {RNA1509_22976} {RNA1310_9502} {RNA815_8881} |
|
21. | MligTC455_37220 | 580 | 12.09 | Mlig455_052567, Mlig455_065350 | Neo: - Age: - Region-enriched R8: 7.789/0.00000 |
FMNL1, FMNL3 | 1.89 | - | - | 0.939 | - | - | 0.951 | Mlig455_052567 {REF} {Length: 3222} {Pfam: Formin Homology 2 Domain [PF02181.25, score=164.8]} {Human: ENSG00000161791, FMNL3, formin like 3, [Score=115, Expect=2e-25]; ENSG00000184922, FMNL1, formin like 1, [Score=113, Expect=4e-25]; ENSG00000157827, FMNL2, formin like 2, [Score=112, Expect=1e-24]} {Mouse: ENSMUSG00000055805, Fmnl1, formin-like 1, [Score=121, Expect=1e-27]; ENSMUSG00000023008, Fmnl3, formin-like 3, [Score=118, Expect=2e-26]} {Dmel: FBgn0267795, Frl, Formin-like, [Score=101, Expect=2e-21]} {Celegans: WBGene00021698, frl-1, FRL (Formin Related gene in Leukocytes) homolog, [Score=84.7, Expect=2e-16]} {Smed: dd_Smed_v6_3917_0_2, dd_Smed_v6_3917_0_2, [Score=79.0, Expect=8e-15]} {RNA1509_29857, RNA1509_51590} {RNA1310_4919, RNA1509_29857, RNA1509_51590} {RNA1509_29857, RNA1509_51590, RNA815_9351} Mlig455_065350 {REF} {Length: 3132} {Pfam: Formin Homology 2 Domain [PF02181.25, score=113.1]} {Human: ENSG00000184922, FMNL1, formin like 1, [Score=84.7, Expect=9e-18]; ENSG00000157827, FMNL2, formin like 2, [Score=84.0, Expect=2e-17]; ENSG00000161791, FMNL3, formin like 3, [Score=83.2, Expect=5e-17]} {Mouse: ENSMUSG00000055805, Fmnl1, formin-like 1, [Score=93.6, Expect=1e-20]} {Dmel: FBgn0025641, DAAM, Dishevelled Associated Activator of Morphogenesis, [Score=67.8, Expect=3e-12]} {Smed: dd_Smed_v6_2533_0_1, dd_Smed_v6_2533_0_1, [Score=56.6, Expect=9e-09]} {RNA1509_51590} {RNA1310_4919} {RNA815_16059} |
22. | MligTC455_38616 | 55 | 1.15 | Mlig455_043530 | Neo: - Age: Up-Down-Down |
SLC6A5 | 1.888 | - | - | - | - | 0.958 | 0.930 | Mlig455_043530 {REF} {Length: 3918} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=690.2]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [RH, Score=583, Expect=0.0]; ENSG00000196517, SLC6A9, solute carrier family 6 member 9, [RH, Score=563, Expect=0.0]; ENSG00000011083, SLC6A7, solute carrier family 6 member 7, [RH, Score=554, Expect=0.0]} {Mouse: ENSMUSG00000028542, Slc6a9, solute carrier family 6 (neurotransmitter transporter, glycine), member 9, [RH, Score=558, Expect=0.0]; ENSMUSG00000052026, Slc6a7, solute carrier family 6 (neurotransmitter transporter, L-proline), member 7, [RH, Score=555, Expect=0.0]} {Dmel: FBgn0034911, CG5549, [RH, Score=549, Expect=0.0]} {Celegans: WBGene00004910, snf-11, Transporter, [Score=465, Expect=1e-156]} {Smed: dd_Smed_v6_3642_0_2, dd_Smed_v6_3642_0_2, [Score=525, Expect=4e-180]} {RNA1509_17343} {RNA1310_77174, RNA1509_17343} {RNA1509_17343, RNA815_36520} |
23. | MligTC455_15983 | 668 | 13.92 | Mlig455_018780, Mlig455_018950 | Neo: - Age: Up-Down-Down Region-enriched R8: 4.299/0.00000 |
1.887 | - | - | 0.971 | - | - | 0.916 | Mlig455_018780 {REF} {Length: 1496} {RNA1509_47436} {RNA1310_22809.1} {RNA815_49713} Mlig455_018950 {REF} {Length: 1264} {RNA1509_47436} {RNA1310_22809.1, RNA1509_47436} {RNA1509_47436, RNA815_49713} |
|
24. | MligTC455_23202 | 2035 | 42.39 | Mlig455_049148, Mlig455_049198 | Neo: - Age: Down-Down-Up Region-enriched R3: 7.168/0.00000 |
1.876 | - | - | - | 0.903 | 0.973 | - | Mlig455_049148 {REF} {Length: 686} {Pfam: CUB domain [PF00431.22, score=29.6]} {Celegans: WBGene00008596, clec-54, C-type LECtin, [Score=44.3, Expect=1e-05]} {RNA1509_15319, RNA1509_26181} {RNA1310_56206, RNA1509_15319, RNA1509_26181} {RNA1509_15319, RNA1509_26181, RNA815_28296} Mlig455_049198 {REF} {Length: 687} {Pfam: CUB domain [PF00431.22, score=29.3]} {Celegans: WBGene00008596, clec-54, C-type LECtin, [Score=44.3, Expect=1e-05]} {RNA1509_29109} {RNA1310_56206, RNA1509_29109} {RNA1509_29109, RNA815_28296} |
|
25. | MligTC455_22056 | 44 | 0.91 | Mlig455_002130 | Neo: - Age: Up-Down-Up |
DHX38 | 1.875 | - | - | 0.952 | - | - | 0.923 | Mlig455_002130 {REF} {Length: 5123} {Pfam: WWE domain [PF02825.22, score=85.5]; Helicase conserved C-terminal domain [PF00271.33, score=47.2]; Helicase associated domain (HA2) [PF04408.25, score=27.8]} {Human: ENSG00000140829, DHX38, DEAH-box helicase 38, [Score=258, Expect=2e-70]; ENSG00000067596, DHX8, DEAH-box helicase 8, [Score=248, Expect=6e-67]} {Mouse: ENSMUSG00000037993, Dhx38, DEAH (Asp-Glu-Ala-His) box polypeptide 38, [Score=259, Expect=1e-70]; ENSMUSG00000034931, Dhx8, DEAH (Asp-Glu-Ala-His) box polypeptide 8, [Score=248, Expect=5e-67]} {Dmel: FBgn0086895, pea, peanuts, [Score=243, Expect=1e-65]} {Celegans: WBGene00003389, mog-1, Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1, [Score=265, Expect=4e-73]} {Smed: dd_Smed_v6_9191_0_1, dd_Smed_v6_9191_0_1, [Score=249, Expect=1e-71]} {RNA1509_29316} {RNA1310_42675} {RNA815_24379} |
26. | MligTC455_37780 | 169 | 3.52 | Mlig455_010706 | Neo: - Age: - |
1.875 | - | - | - | - | 0.893 | 0.982 | Mlig455_010706 {REF} {Length: 723} {RNA1310_80804} | |
27. | MligTC455_37085 | 47 | 0.97 | Mlig455_054670 | Neo: - Age: - |
1.856 | - | - | 0.962 | - | - | 0.894 | Mlig455_054670 {REF} {Length: 4438} {RNA1509_44394} {RNA1310_6796} {RNA815_32860} | |
28. | MligTC455_39000 | 222 | 4.62 | Mlig455_055114 | Neo: - Age: - Region-enriched R8: 3.634/0.01137 |
1.852 | - | - | 0.891 | - | - | 0.961 | Mlig455_055114 {REF} {Length: 3533} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=21.4]} {Smed: dd_Smed_v6_14472_0_32, dd_Smed_v6_14472_0_32, [Score=47.8, Expect=5e-09]} {RNA1509_7715} {RNA1310_20361} {RNA815_2054.1} | |
29. | MligTC455_18395 | 39 | 0.8 | Mlig455_053780 | Neo: - Age: - |
MECOM | 1.847 | - | - | - | 0.889 | 0.958 | - | Mlig455_053780 {REF} {Length: 1146} {Pfam: Zinc-finger double domain [PF13465.8, score=63.0]; Zinc finger, C2H2 type [PF00096.28, score=48.8]; C2H2-type zinc finger [PF13894.8, score=33.6]; C2H2-type zinc-finger domain [PF13909.8, score=26.9]; Drought induced 19 protein (Di19), zinc-binding [PF05605.14, score=23.9]; GAGA factor [PF09237.13, score=18.9]} {Human: ENSG00000085276, MECOM, MDS1 and EVI1 complex locus, [Score=133, Expect=6e-34]; ENSG00000142611, PRDM16, PR/SET domain 16, [Score=132, Expect=8e-34]} {Mouse: ENSMUSG00000039410, Prdm16, PR domain containing 16, [Score=133, Expect=5e-34]; ENSMUSG00000027684, Mecom, MDS1 and EVI1 complex locus, [Score=133, Expect=3e-34]} {Dmel: FBgn0032707, CG10348, [Score=132, Expect=3e-34]} {Celegans: WBGene00001207, egl-43, Egl-43, [RH, Score=97.8, Expect=3e-23]} {Smed: dd_Smed_v6_22685_0_1, dd_Smed_v6_22685_0_1, [Score=134, Expect=1e-36]} {RNA1310_48534} {RNA815_4264.1} |
30. | MligTC455_37338 | 40 | 0.84 | Mlig455_035280 | Neo: - Age: - |
1.843 | - | - | - | 0.875 | 0.968 | - | Mlig455_035280 {REF} {Length: 2442} {RNA1310_17149} {RNA815_15957} | |
31. | MligTC455_38827 | 168 | 3.49 | Mlig455_065185 | Neo: - Age: - Region-enriched R8: 3.346/0.01415 |
RDX | 1.841 | - | - | 0.881 | - | - | 0.960 | Mlig455_065185 {REF} {Length: 3409} {Pfam: Ezrin/radixin/moesin family [PF00769.21, score=106.5]; FERM C-terminal PH-like domain [PF09380.12, score=87.8]; FERM central domain [PF00373.20, score=83.0]; FERM N-terminal domain [PF09379.12, score=66.5]} {Human: ENSG00000137710, RDX, radixin, [RH, Score=589, Expect=0.0]; ENSG00000092820, EZR, ezrin, [RH, Score=577, Expect=0.0]; ENSG00000147065, MSN, moesin, [RH, Score=561, Expect=0.0]} {Mouse: ENSMUSG00000032050, Rdx, radixin, [RH, Score=586, Expect=0.0]; ENSMUSG00000031207, Msn, moesin, [RH, Score=557, Expect=0.0]} {Dmel: FBgn0011661, Moe, Moesin, [RH, Score=514, Expect=5e-174]} {Celegans: WBGene00001333, erm-1, ERM-1B; Ezrin/Radixin/Moesin, [Score=545, Expect=0.0]} {Smed: dd_Smed_v6_8101_0_1, dd_Smed_v6_8101_0_1, [Score=504, Expect=7e-172]} {RNA1509_50666} {RNA1310_19690} {RNA815_6880} |
32. | MligTC455_53572 | 2350 | 48.96 | Mlig455_010811 | Neo: - Age: Down-Up-Down Region-enriched R8: 7.256/0.00000 |
LMNB1 | 1.834 | - | - | 0.953 | - | - | 0.881 | Mlig455_010811 {REF} {Length: 2584} {Pfam: Intermediate filament protein [PF00038.23, score=182.9]; Lamin Tail Domain [PF00932.21, score=45.3]; Septation ring formation regulator, EzrA [PF06160.14, score=24.8]} {Human: ENSG00000113368, LMNB1, lamin B1, [Score=182, Expect=7e-49]; ENSG00000160789, LMNA, lamin A/C, [Score=177, Expect=6e-47]} {Mouse: ENSMUSG00000024590, Lmnb1, lamin B1, [Score=180, Expect=2e-48]; ENSMUSG00000028063, Lmna, lamin A, [Score=172, Expect=2e-45]} {Dmel: FBgn0002525, Lam, Lamin, [RH, Score=201, Expect=9e-56]} {Celegans: WBGene00002050, ifa-1, Intermediate filament protein ifa-1, [RH, Score=403, Expect=7e-133]} {Smed: dd_Smed_v6_3871_0_1, dd_Smed_v6_3871_0_1, [RH, Score=578, Expect=0.0]} {RNA1509_3449} {RNA1310_9642} {RNA815_3251.1} |
33. | MligTC455_40482 | 206 | 4.3 | Mlig455_035109, Mlig455_062419 | Neo: - Age: - |
1.83 | - | - | - | 0.868 | 0.962 | - | Mlig455_035109 {REF} {Length: 1527} {Pfam: emp24/gp25L/p24 family/GOLD [PF01105.26, score=20.2]} {RNA1509_41958} {RNA1310_29720, RNA1509_41958} {RNA1509_41958, RNA815_13581.1} Mlig455_062419 {REF} {Length: 1210} {Pfam: emp24/gp25L/p24 family/GOLD [PF01105.26, score=20.4]} {RNA1509_41958} {RNA1310_29720} {RNA815_13581.1} |
|
34. | MligTC455_04170 | 65 | 1.36 | Mlig455_000555, Mlig455_030353 | Neo: - Age: - |
FGG | 1.817 | - | - | - | 0.834 | 0.983 | - | Mlig455_000555 {REF} {Length: 1133} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=125.0]} {Human: ENSG00000171557, FGG, fibrinogen gamma chain, [Score=103, Expect=3e-24]; ENSG00000120332, TNN, tenascin N, [Score=98.2, Expect=3e-22]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=102, Expect=6e-25]; ENSMUSG00000026938, Fcna, ficolin A, [Score=99.4, Expect=1e-23]; ENSMUSG00000033860, Fgg, fibrinogen gamma chain, [Score=98.2, Expect=9e-23]; ENSMUSG00000026725, Tnn, tenascin N, [Score=98.2, Expect=2e-22]} {Dmel: FBgn0051832, CG31832, [Score=88.2, Expect=2e-20]} {Celegans: WBGene00020516, T15B7.1, [Score=62.4, Expect=8e-11]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=72.4, Expect=4e-14]} {RNA1310_33683.2} {RNA815_41841} Mlig455_030353 {REF} {Length: 1214} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=126.3]} {Human: ENSG00000171557, FGG, fibrinogen gamma chain, [Score=103, Expect=3e-24]; ENSG00000120332, TNN, tenascin N, [Score=99.4, Expect=3e-22]; ENSG00000160339, FCN2, ficolin 2, [Score=98.2, Expect=6e-23]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=102, Expect=1e-24]; ENSMUSG00000026938, Fcna, ficolin A, [Score=100, Expect=1e-23]; ENSMUSG00000026725, Tnn, tenascin N, [Score=99.0, Expect=2e-22]; ENSMUSG00000033860, Fgg, fibrinogen gamma chain, [Score=99.0, Expect=9e-23]} {Dmel: FBgn0051832, CG31832, [Score=92.0, Expect=9e-22]} {Celegans: WBGene00020516, T15B7.1, [Score=63.2, Expect=4e-11]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=75.9, Expect=4e-15]} {RNA1310_33683.2} {RNA815_41841} |
35. | MligTC455_40481 | 110 | 2.28 | Mlig455_009942 | Neo: - Age: - |
1.81 | - | - | - | 0.851 | 0.959 | - | Mlig455_009942 {REF} {Length: 2365} {Pfam: emp24/gp25L/p24 family/GOLD [PF01105.26, score=57.8]} {RNA1509_41958} {RNA1310_23710} {RNA815_10791} | |
36. | MligTC455_43297 | 231 | 4.8 | Mlig455_016228, Mlig455_054259 | Neo: - Age: - Regeneration-downregulated BL: -6.831 Regeneration-depleted BL: -6.831 |
CLRN2 | 1.803 | - | - | 0.836 | - | - | 0.967 | Mlig455_016228 {REF} {Length: 1111} {Human: ENSG00000249581, CLRN2, clarin 2, [Score=52.4, Expect=2e-07]} {Mouse: ENSMUSG00000049530, Clrn2, clarin 2, [Score=48.9, Expect=2e-06]} {Dmel: FBgn0037235, CG1103, [Score=48.9, Expect=1e-06]} {RNA1310_36935} {RNA815_22076} Mlig455_054259 {REF} {Length: 1504} {Human: ENSG00000249581, CLRN2, clarin 2, [Score=52.4, Expect=1e-07]} {Mouse: ENSMUSG00000049530, Clrn2, clarin 2, [Score=48.9, Expect=1e-06]} {Dmel: FBgn0037235, CG1103, [Score=49.3, Expect=9e-07]} {RNA1509_16036} {RNA1310_36935} {RNA815_22076} |
37. | MligTC455_47735 | 70 | 1.45 | Mlig455_054644 | Neo: - Age: - Region-enriched R3: 5.950/0.00023 |
1.8 | - | - | - | 0.849 | 0.951 | - | Mlig455_054644 {REF} {Length: 804} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=37.7]} {RNA1509_39145} {RNA1310_42379.1} {RNA815_34286.1} | |
38. | MligTC455_23857 | 179 | 3.73 | Mlig455_011373 | Neo: - Age: - |
KCNN2 | 1.798 | - | - | - | 0.817 | 0.981 | - | Mlig455_011373 {REF} {Length: 4119} {Pfam: Calcium-activated SK potassium channel [PF03530.16, score=144.8]; Calmodulin binding domain [PF02888.18, score=112.8]; Ion channel [PF07885.18, score=51.5]} {Human: ENSG00000080709, KCNN2, potassium calcium-activated channel subfamily N member 2, [RH, Score=541, Expect=4e-180]; ENSG00000143603, KCNN3, potassium calcium-activated channel subfamily N member 3, [RH, Score=534, Expect=5e-179]; ENSG00000105642, KCNN1, potassium calcium-activated channel subfamily N member 1, [RH, Score=514, Expect=4e-174]} {Mouse: ENSMUSG00000054477, Kcnn2, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2, [RH, Score=543, Expect=0.0]; ENSMUSG00000000794, Kcnn3, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3, [RH, Score=533, Expect=7e-179]} {Dmel: FBgn0029761, SK, small conductance calcium-activated potassium channel, [RH, Score=602, Expect=0.0]} {Celegans: WBGene00008570, kcnl-2, KCNL-2 variant; KCNN (Potassium K ChaNNel, calcium activated)-Like, [RH, Score=428, Expect=5e-137]} {Smed: dd_Smed_v6_14006_0_1, dd_Smed_v6_14006_0_1, [RH, Score=552, Expect=0.0]} {RNA1509_39011, RNA1509_39273} {RNA1310_12409, RNA1509_39011, RNA1509_39273} {RNA1509_39011, RNA1509_39273, RNA815_5551} |
39. | MligTC455_13779 | 36 | 0.75 | Mlig455_058271 | Neo: - Age: - |
1.797 | - | - | 0.961 | - | - | 0.836 | Mlig455_058271 {REF} {Length: 579} {NoTransDecoderORF} {RNA1509_56620} {RNA1310_126618} {RNA815_11857} | |
40. | MligTC455_33004 | 291 | 6.07 | Mlig455_035954, Mlig455_058423 | Neo: - Age: Down-Up-Up Region-enriched R8: 3.765/0.00001 |
LRP12 | 1.796 | - | - | 0.968 | - | - | 0.828 | Mlig455_035954 {REF} {Length: 2125} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=37.1]} {Human: ENSG00000147650, LRP12, LDL receptor related protein 12, [Score=49.3, Expect=3e-06]; ENSG00000171208, NETO2, neuropilin and tolloid like 2, [Score=47.4, Expect=1e-05]} {Mouse: ENSMUSG00000022305, Lrp12, low density lipoprotein-related protein 12, [Score=49.7, Expect=2e-06]} {RNA1509_18736} {RNA1310_23783.1} {RNA815_18491} Mlig455_058423 {REF} {Length: 1426} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=37.1]} {Human: ENSG00000147650, LRP12, LDL receptor related protein 12, [Score=49.3, Expect=3e-06]; ENSG00000171208, NETO2, neuropilin and tolloid like 2, [Score=48.5, Expect=6e-06]} {Mouse: ENSMUSG00000022305, Lrp12, low density lipoprotein-related protein 12, [Score=49.7, Expect=2e-06]; ENSMUSG00000036902, Neto2, neuropilin (NRP) and tolloid (TLL)-like 2, [Score=48.5, Expect=4e-06]} {RNA1310_23783.1} {RNA815_18491} |
41. | MligTC455_16780 | 59 | 1.22 | Mlig455_003112, Mlig455_062777 | Neo: - Age: - |
1.788 | - | - | - | 0.795 | 0.993 | - | Mlig455_003112 {REF} {Length: 1644} {Pfam: PAN domain [PF14295.8, score=23.1]} {RNA1509_48973} {RNA1310_82250} {RNA815_43010} Mlig455_062777 {REF} {Length: 1721} {RNA1509_48973} {RNA1310_82250} {RNA815_43010} |
|
42. | MligTC455_26653 | 3263 | 67.97 | Mlig455_049144, Mlig455_049196 | Neo: - Age: Down-Down-Up, logFC(26M/2M)=-0.518 Region-specific R3: 7.699 Region-enriched R3: 6.693/0.00000 |
1.784 | - | - | - | 0.807 | 0.977 | - | Mlig455_049144 {REF} {Length: 862} {Pfam: CUB domain [PF00431.22, score=21.5]} {RNA1509_5316} {RNA1310_45244} {RNA815_23025} Mlig455_049196 {REF} {Length: 3464} {Pfam: CUB domain [PF00431.22, score=21.5]} {RNA1509_23994, RNA1509_5316} {RNA1310_45244, RNA1509_23994, RNA1509_5316} {RNA1509_23994, RNA1509_5316, RNA815_23025} |
|
43. | MligTC455_32613 | 115 | 2.4 | Mlig455_019212 | Neo: - Age: logFC(26M/2M)=-0.399 |
STAC | 1.781 | - | - | 0.818 | - | - | 0.963 | Mlig455_019212 {REF} {Length: 3658} {Pfam: Variant SH3 domain [PF14604.8, score=37.9]; SH3 domain [PF00018.30, score=37.8]; Variant SH3 domain [PF07653.19, score=22.2]} {Human: ENSG00000144681, STAC, SH3 and cysteine rich domain, [Score=64.3, Expect=3e-10]; ENSG00000141750, STAC2, SH3 and cysteine rich domain 2, [Score=63.2, Expect=1e-09]} {Mouse: ENSMUSG00000032502, Stac, src homology three (SH3) and cysteine rich domain, [Score=67.0, Expect=3e-11]} {Dmel: FBgn0263980, CG43729, [RH, Score=97.1, Expect=1e-20]} {Celegans: WBGene00006791, unc-57, Endophilin-A homolog, [Score=49.3, Expect=4e-07]} {Smed: dd_Smed_v6_14652_0_1, dd_Smed_v6_14652_0_1, [RH, Score=185, Expect=2e-48]} {RNA1509_45601} {RNA1310_13004, RNA1509_45601} {RNA1509_45601, RNA815_25263} |
44. | MligTC455_43083 | 230 | 4.79 | Mlig455_010304, Mlig455_010335, Mlig455_065656 | Neo: - Age: - |
AHNAK | 1.772 | - | - | 0.781 | - | 0.991 | - | Mlig455_010304 {REF} {Length: 1799} {TRANSSPLICED} {Human: ENSG00000124942, AHNAK, AHNAK nucleoprotein, [Score=48.9, Expect=3e-06]} {Mouse: ENSMUSG00000069833, Ahnak, AHNAK nucleoprotein (desmoyokin), [Score=54.3, Expect=2e-08]} {RNA1310_47293.1} {RNA815_36129} Mlig455_010335 {REF} {Length: 540} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_47293.1} {RNA815_36129} Mlig455_065656 {REF} {Length: 1733} {TRANSSPLICED} {RNA1310_47293.1} {RNA815_36129} |
45. | MligTC455_07459 | 99 | 2.06 | Mlig455_006481 | Neo: - Age: - Region-enriched R7: 5.737/0.00000 |
1.771 | - | - | 0.812 | - | - | 0.959 | Mlig455_006481 {REF} {Length: 920} {NoTransDecoderORF} {RNA1310_80600} {RNA815_38048.2} | |
46. | MligTC455_51029 | 340 | 7.09 | Mlig455_056736 | Neo: - |
1.768 | - | - | - | 0.809 | 0.959 | - | Mlig455_056736 {REF} {Length: 850} {RNA1509_4527} {RNA1310_27536} {RNA815_19650} | |
47. | MligTC455_26474 | 257 | 5.36 | Mlig455_023312 | Neo: Irradiation Age: Up-Down-Up Region-enriched R3: 5.747/0.00000 |
OTOG | 1.767 | - | - | - | 0.807 | 0.960 | - | Mlig455_023312 {REF} {Length: 3545} {Pfam: Cystine-knot domain [PF00007.24, score=40.6]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=28.4]} {Human: ENSG00000188162, OTOG, otogelin, [Score=53.9, Expect=6e-07]} {Mouse: ENSMUSG00000048191, Muc6, mucin 6, gastric, [Score=50.4, Expect=4e-06]} {Smed: dd_Smed_v6_3185_0_1, dd_Smed_v6_3185_0_1, [Score=210, Expect=6e-62]} {RNA1509_42162} {RNA1310_2753} {RNA815_1083.1} |
48. | MligTC455_52242 | 83 | 1.72 | Mlig455_064773 | Neo: - Age: - |
1.761 | - | - | - | 0.775 | 0.986 | - | Mlig455_064773 {REF} {Length: 2999} {tRNA: Undet(NNN),pseudo, score=21.6} {Pfam: FAM217 family [PF15344.8, score=31.7]} {RNA1509_38818} {RNA1310_9551, RNA1509_38818} {RNA1509_38818, RNA815_15248} | |
49. | MligTC455_32563 | 900 | 18.74 | Mlig455_021721 | Neo: - Age: Down-Down-Up, logFC(26M/2M)=-0.879 Region-enriched R2: 4.965/0.00011 |
1.759 | - | - | - | 0.809 | 0.950 | - | Mlig455_021721 {REF} {Length: 1079} {RNA1509_570} {RNA1310_40828} {RNA815_5866.1} | |
50. | MligTC455_47733 | 81 | 1.69 | Mlig455_044125 | Neo: - Age: logFC(26M/2M)=0.424 Region-enriched R6: 4.050/0.00363 Regeneration-downregulated R6: -6.610 Regeneration-depleted R6: -6.610 |
1.751 | - | - | - | 0.781 | - | 0.970 | Mlig455_044125 {REF} {Length: 4219} {Pfam: Peptidase family M13 [PF05649.15, score=42.8]} {RNA1310_43623} {RNA815_36140} | |
51. | MligTC455_14375 | 163 | 3.4 | Mlig455_056945 | Neo: - Age: - |
1.748 | - | - | - | - | 0.787 | 0.961 | Mlig455_056945 {REF} {Length: 1764} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=49.6]} {Smed: dd_Smed_v6_32358_0_1, dd_Smed_v6_32358_0_1, [Score=94.4, Expect=4e-22]} {RNA1509_48719} {RNA1310_16266.1} {RNA815_10544.2} | |
52. | MligTC455_37658 | 1892 | 39.42 | Mlig455_001025, Mlig455_064203, Mlig455_065673 | Neo: - Age: - Region-enriched R3: 5.362/0.00000 |
TECTA, ZAN | 1.748 | - | - | - | 0.782 | 0.966 | - | Mlig455_001025 {REF} {Length: 14015} {Pfam: von Willebrand factor type A domain [PF00092.30, score=106.5]; von Willebrand factor type A domain [PF13519.8, score=105.1]; von Willebrand factor type D domain [PF00094.27, score=103.2]; Calcium-binding EGF domain [PF07645.17, score=83.3]; Galactose binding lectin domain [PF02140.20, score=68.2]; C8 domain [PF08742.13, score=47.6]; von Willebrand factor type A domain [PF13768.8, score=46.5]; EGF domain [PF12947.9, score=40.8]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=34.2]; Fibronectin type II domain [PF00040.21, score=29.8]; Complement Clr-like EGF-like [PF12662.9, score=20.5]} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=179, Expect=9e-44]; ENSG00000109927, TECTA, tectorin alpha, [Score=178, Expect=2e-43]; ENSG00000281123, FCGBP, Fc fragment of IgG binding protein, [Score=176, Expect=9e-43]; ENSG00000275395, FCGBP, Fc fragment of IgG binding protein, [Score=171, Expect=1e-41]} {Mouse: ENSMUSG00000047730, Fcgbp, Fc fragment of IgG binding protein, [Score=184, Expect=2e-45]; ENSMUSG00000037705, Tecta, tectorin alpha, [Score=179, Expect=8e-44]} {Dmel: FBgn0053196, dpy, dumpy, [Score=141, Expect=1e-32]} {Celegans: WBGene00001403, fbl-1, Fibulin-1, [Score=128, Expect=2e-29]} {Smed: dd_Smed_v6_1748_0_1, dd_Smed_v6_1748_0_1, [RH, Score=530, Expect=1e-155]} {RNA1509_4373} {RNA1310_104.1} {RNA815_50} Mlig455_064203 {REF} {Length: 18445} {Pfam: von Willebrand factor type A domain [PF13519.8, score=150.3]; von Willebrand factor type A domain [PF00092.30, score=130.4]; von Willebrand factor type D domain [PF00094.27, score=103.4]; Calcium-binding EGF domain [PF07645.17, score=81.7]; Galactose binding lectin domain [PF02140.20, score=68.0]; von Willebrand factor type A domain [PF13768.8, score=55.6]; C8 domain [PF08742.13, score=47.3]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=34.0]; EGF domain [PF12947.9, score=32.4]; Fibronectin type II domain [PF00040.21, score=29.5]; Complement Clr-like EGF-like [PF12662.9, score=20.2]} {Human: ENSG00000109927, TECTA, tectorin alpha, [Score=181, Expect=4e-44]; ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=179, Expect=1e-43]; ENSG00000281123, FCGBP, Fc fragment of IgG binding protein, [Score=175, Expect=3e-42]} {Mouse: ENSMUSG00000047730, Fcgbp, Fc fragment of IgG binding protein, [Score=183, Expect=6e-45]; ENSMUSG00000037705, Tecta, tectorin alpha, [Score=181, Expect=1e-44]} {Dmel: FBgn0053196, dpy, dumpy, [Score=141, Expect=3e-32]} {Celegans: WBGene00001403, fbl-1, Fibulin-1, [Score=130, Expect=6e-30]} {Smed: dd_Smed_v6_1748_0_1, dd_Smed_v6_1748_0_1, [Score=525, Expect=7e-154]} {RNA1509_4373} {RNA1310_104.1} {RNA815_50} Mlig455_065673 {REF} {Length: 1867} {RNA1509_3700} {RNA1310_2063.1} {RNA815_470} |
53. | MligTC455_47736 | 1775 | 36.98 | Mlig455_054650 | Neo: - Age: logFC(26M/2M)=-0.375 Region-enriched R3: 5.288/0.00000 |
1.748 | - | - | - | 0.797 | 0.951 | - | Mlig455_054650 {REF} {Length: 1247} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=86.5]} {RNA1509_13769, RNA1509_51431} {RNA1310_40941.1, RNA1509_13769, RNA1509_51431} {RNA1509_13769, RNA1509_51431, RNA815_34286.1} | |
54. | MligTC455_38796 | 1266 | 26.37 | Mlig455_060220, Mlig455_060235 | Neo: - Age: Down-Down-Up Region-enriched R8: 6.521/0.00003 |
BACE1 | 1.747 | - | - | 0.795 | - | - | 0.952 | Mlig455_060220 {REF} {Length: 1841} {Pfam: Eukaryotic aspartyl protease [PF00026.25, score=72.8]; Xylanase inhibitor C-terminal [PF14541.8, score=19.9]} {Human: ENSG00000186318, BACE1, beta-secretase 1, [Score=215, Expect=3e-63]} {Mouse: ENSMUSG00000032086, Bace1, beta-site APP cleaving enzyme 1, [Score=214, Expect=5e-63]} {Dmel: FBgn0032304, CG17134, [Score=56.2, Expect=3e-08]} {Celegans: WBGene00000218, asp-5, ASpartyl Protease, [Score=47.8, Expect=1e-05]} {RNA1509_48153} {RNA1310_17192, RNA1509_48153} {RNA1509_48153, RNA815_50706} Mlig455_060235 {REF} {Length: 1482} {Human: ENSG00000186318, BACE1, beta-secretase 1, [Score=119, Expect=2e-29]} {Mouse: ENSMUSG00000032086, Bace1, beta-site APP cleaving enzyme 1, [Score=118, Expect=1e-28]} {RNA1509_48153} {RNA1310_17192} {RNA815_51940} |
55. | MligTC455_28721 | 5194 | 108.2 | Mlig455_032217 | Neo: - Age: Down-Down-Up, logFC(26M/2M)=0.434 Region-specific R2: 4.415 Region-enriched R2: 3.899/0.00001 |
1.746 | - | - | - | 0.791 | 0.955 | - | Mlig455_032217 {REF} {Length: 1138} {RNA1509_13111, RNA1509_14080, RNA1509_28175, RNA1509_53802, RNA1509_7170} {RNA1310_32043.1, RNA1509_13111, RNA1509_28175, RNA1509_53802, RNA1509_7170} {RNA1509_13111, RNA1509_28175, RNA1509_53802, RNA1509_7170, RNA815_14905} | |
56. | MligTC455_28722 | 5157 | 107.43 | Mlig455_054221 | Neo: - Age: Down-Down-Up Region-specific R2: 4.518 Region-enriched R2: 3.867/0.00001 |
1.744 | - | - | - | 0.783 | 0.961 | - | Mlig455_054221 {REF} {Length: 1624} {RNA1509_14080, RNA1509_47772} {RNA1310_32043.1, RNA1509_47772} {RNA1509_47772, RNA815_14905} | |
57. | MligTC455_45518 | 6058 | 126.2 | Mlig455_035564 | Neo: - Age: Up-Down-Up, logFC(26M/2M)=0.828 Region-enriched R3: 6.058/0.00000 |
1.743 | - | - | - | 0.772 | 0.971 | - | Mlig455_035564 {REF} {Length: 516} {RNA1509_2707} {RNA1310_17478.1} {RNA815_12018.1} | |
58. | MligTC455_04509 | 308 | 6.42 | Mlig455_015097, Mlig455_015215 | Neo: - Age: - Region-enriched R3: 2.768/0.00001 Regeneration-downregulated BL: -7.255 Regeneration-depleted BL: -7.255 |
C1GALT1 | 1.74 | - | - | - | - | 0.976 | 0.764 | Mlig455_015097 {REF} {Length: 1363} {Pfam: Galactosyltransferase [PF01762.23, score=33.1]; Fringe-like [PF02434.18, score=32.5]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=162, Expect=2e-46]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=165, Expect=1e-47]} {Dmel: FBgn0032078, C1GalTA, Core 1 Galactosyltransferase A, [Score=183, Expect=3e-54]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=183, Expect=3e-54]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=188, Expect=1e-56]} {RNA1509_52982} {RNA1310_22738.1} {RNA815_21441} Mlig455_015215 {REF} {Length: 2494} {Pfam: Fringe-like [PF02434.18, score=59.2]; Galactosyltransferase [PF01762.23, score=57.8]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=175, Expect=3e-48]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=172, Expect=1e-47]} {Dmel: FBgn0032078, C1GalTA, Core 1 Galactosyltransferase A, [Score=184, Expect=7e-52]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=183, Expect=2e-51]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=188, Expect=8e-54]} {RNA1509_52982} {RNA1310_22738.1} {RNA815_21441} |
59. | MligTC455_10599 | 140 | 2.91 | Mlig455_000565, Mlig455_030365, Mlig455_030412 | Neo: - Age: logFC(26M/2M)=-0.762 |
GRIK3 | 1.74 | - | - | - | 0.782 | 0.958 | - | Mlig455_000565 {REF} {Length: 2846} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=72.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=56.1]; Ligand-gated ion channel [PF00060.28, score=44.5]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=145, Expect=3e-35]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=142, Expect=3e-34]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=141, Expect=5e-34]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=139, Expect=3e-33]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=144, Expect=5e-35]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=143, Expect=1e-34]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=140, Expect=9e-34]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=139, Expect=2e-33]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=138, Expect=5e-33]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=138, Expect=4e-33]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=130, Expect=1e-30]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=135, Expect=3e-32]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=154, Expect=2e-38]} {RNA1509_59839} {RNA1310_4586} {RNA815_2154.1} Mlig455_030365 {REF} {Length: 2765} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=72.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=57.7]; Ligand-gated ion channel [PF00060.28, score=43.6]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=144, Expect=6e-35]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=140, Expect=2e-33]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=138, Expect=7e-33]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=138, Expect=7e-33]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=137, Expect=2e-32]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=142, Expect=2e-34]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=142, Expect=2e-34]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=138, Expect=4e-33]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=136, Expect=2e-32]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=136, Expect=2e-32]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=130, Expect=6e-31]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=131, Expect=3e-31]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=155, Expect=7e-39]} {RNA1509_59839} {RNA1310_4586} {RNA815_2154.1} Mlig455_030412 {REF} {Length: 2615} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=72.2]; Ligand-gated ion channel [PF00060.28, score=45.1]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=36.1]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=125, Expect=6e-29]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=122, Expect=6e-28]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=121, Expect=1e-27]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=125, Expect=4e-29]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=124, Expect=6e-29]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=120, Expect=2e-27]} {Dmel: FBgn0026255, clumsy, [Score=117, Expect=9e-27]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=117, Expect=7e-27]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=135, Expect=1e-32]} {RNA1509_59839} {RNA1310_4586} {RNA815_2154.1} |
60. | MligTC455_53260 | 241 | 5.03 | Mlig455_000055 | Neo: - Age: - Regeneration-downregulated BL: -7.534 Regeneration-depleted BL: -7.534 |
CALM2 | 1.735 | - | - | - | 0.767 | - | 0.968 | Mlig455_000055 {REF} {Length: 1296} {Pfam: EF hand [PF00036.34, score=104.3]; EF-hand domain pair [PF13499.8, score=101.0]; EF-hand domain [PF13405.8, score=85.6]; EF-hand domain pair [PF13833.8, score=69.9]; EF hand [PF13202.8, score=68.0]; EF-hand domain [PF14658.8, score=45.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=32.6]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=26.3]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=181, Expect=4e-58]; ENSG00000178363, CALML3, calmodulin like 3, [Score=177, Expect=6e-57]; ENSG00000198668, CALM1, calmodulin 1, [Score=176, Expect=8e-57]; ENSG00000160014, CALM3, calmodulin 3, [Score=176, Expect=8e-57]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=180, Expect=3e-58]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=178, Expect=6e-57]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=176, Expect=6e-57]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=176, Expect=6e-57]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=175, Expect=2e-56]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=174, Expect=3e-56]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=174, Expect=2e-56]} {RNA1509_31596} {RNA1310_27659.1, RNA1509_31596} {RNA1509_31596, RNA815_12079.1} |
61. | MligTC455_52432 | 75 | 1.56 | Mlig455_019213 | Neo: - |
1.73 | - | - | - | 0.776 | - | 0.954 | Mlig455_019213 {REF} {Length: 3040} {RNA1310_29981} {RNA815_46279} | |
62. | MligTC455_19872 | 164 | 3.42 | Mlig455_043990, Mlig455_050696 | Neo: - Age: - Region-enriched R2: 4.725/0.00457 |
1.729 | - | - | - | 0.951 | 0.778 | - | Mlig455_043990 {REF} {Length: 836} {RNA1310_51250} Mlig455_050696 {REF} {Length: 951} {RNA1310_51250} |
|
63. | MligTC455_45517 | 5935 | 123.64 | Mlig455_019215 | Neo: - Age: logFC(26M/2M)=0.286 Region-enriched R3: 6.104/0.00000 |
1.728 | - | - | - | 0.757 | 0.971 | - | Mlig455_019215 {REF} {Length: 894} {RNA1509_2707, RNA1509_2771} {RNA1310_17478.1, RNA1509_2707, RNA1509_2771} {RNA1509_2707, RNA1509_2771, RNA815_12018.1} | |
64. | MligTC455_13917 | 50 | 1.05 | Mlig455_006935, Mlig455_017950 | Neo: - Age: - |
1.722 | - | - | - | - | 0.986 | 0.736 | Mlig455_006935 {REF} {Length: 1553} {RNA1310_24840} {RNA815_41829} Mlig455_017950 {REF} {Length: 1661} {RNA1310_24840} {RNA815_41829} |
|
65. | MligTC455_22400 | 2410 | 50.2 | Mlig455_049145 | Neo: - Age: logFC(26M/2M)=0.314 Region-enriched R3: 6.393/0.00000 |
1.72 | - | - | - | 0.766 | 0.954 | - | Mlig455_049145 {REF} {Length: 929} {RNA1509_6763, RNA1509_7997} {RNA1310_46088, RNA1509_6763, RNA1509_7997} {RNA1509_6763, RNA1509_7997, RNA815_22985} | |
66. | MligTC455_11713 | 8 | 0.16 | Mlig455_030060 | Neo: - Age: - |
1.712 | - | - | - | 0.726 | 0.986 | - | Mlig455_030060 {REF} {Length: 1189} {RNA1310_40798} {RNA815_26160} | |
67. | MligTC455_13098 | 19 | 0.4 | Mlig455_020992 | Neo: - Age: - |
C1GALT1 | 1.712 | - | - | - | 0.755 | 0.957 | - | Mlig455_020992 {REF} {Length: 1108} {Pfam: Galactosyltransferase [PF01762.23, score=27.6]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=160, Expect=3e-46]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=162, Expect=1e-46]} {Dmel: FBgn0032078, C1GalTA, Core 1 Galactosyltransferase A, [Score=138, Expect=8e-38]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=165, Expect=4e-48]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=185, Expect=3e-56]} {RNA1310_125941} |
68. | MligTC455_50827 | 107 | 2.22 | Mlig455_037867 | Neo: - |
WSCD2 | 1.711 | - | - | - | 0.727 | 0.984 | - | Mlig455_037867 {REF} {Length: 912} {Pfam: WSC domain [PF01822.21, score=58.4]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.8, Expect=1e-07]; ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=50.4, Expect=5e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=53.9, Expect=4e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.9, Expect=2e-08]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=46.2, Expect=8e-06]} {RNA1509_59284} {RNA1310_52794.1} {RNA815_21749.1} |
69. | MligTC455_50389 | 19 | 0.39 | Mlig455_059799 | Neo: - Age: - |
1.707 | - | - | - | 0.753 | 0.954 | - | Mlig455_059799 {REF} {Length: 1159} {Pfam: LIM domain [PF00412.24, score=54.9]} {Dmel: FBgn0085354, CG34325, [Score=55.1, Expect=6e-09]} {RNA1310_54844} {RNA815_43129} | |
70. | MligTC455_53956 | 68 | 1.41 | Mlig455_046324 | Neo: - Age: - |
1.704 | - | - | 0.731 | - | 0.973 | - | Mlig455_046324 {REF} {Length: 3358} {RNA1310_18298} {RNA815_25523} | |
71. | MligTC455_25184 | 563 | 11.72 | Mlig455_005207 | Neo: - |
1.703 | - | - | - | 0.733 | 0.970 | - | Mlig455_005207 {REF} {Length: 3047} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=136.2]} {Celegans: WBGene00009073, delm-1, DEgenerin Linked to Mechanosensation, [Score=49.7, Expect=5e-06]} {Smed: dd_Smed_v6_20466_0_2, dd_Smed_v6_20466_0_2, [Score=84.3, Expect=5e-17]} {RNA1509_9013} {RNA1310_7298, RNA1509_9013} {RNA1509_9013, RNA815_2337} | |
72. | MligTC455_22399 | 3614 | 75.29 | Mlig455_049143 | Neo: - Age: Down-Down-Up Region-enriched R3: 6.448/0.00000 |
1.696 | - | - | - | 0.729 | 0.967 | - | Mlig455_049143 {REF} {Length: 1035} {RNA1509_3861, RNA1509_6763} {RNA1310_46088, RNA1509_3861} {RNA1509_3861, RNA815_22985} | |
73. | MligTC455_33878 | 51 | 1.06 | Mlig455_060557 | Neo: - Age: Up-Down-Down |
PKD1L1 | 1.694 | - | - | - | 0.708 | 0.986 | - | Mlig455_060557 {REF} {Length: 10235} {Pfam: Polycystin cation channel [PF08016.14, score=213.7]; PLAT/LH2 domain [PF01477.25, score=42.6]} {Human: ENSG00000158683, PKD1L1, polycystin 1 like 1, transient receptor potential channel interacting, [Score=161, Expect=2e-39]; ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [Score=157, Expect=2e-38]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=195, Expect=3e-50]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=89.0, Expect=1e-17]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=117, Expect=7e-27]} {Smed: dd_Smed_v6_15525_0_1, dd_Smed_v6_15525_0_1, [Score=306, Expect=9e-87]} {RNA1509_40400} {RNA1310_24325} {RNA815_27769} |
74. | MligTC455_53396 | 62 | 1.28 | Mlig455_015104 | Neo: - Age: Down-Up-Down Region-enriched R3: 5.872/0.01335 |
1.692 | - | - | - | 0.721 | 0.971 | - | Mlig455_015104 {REF} {Length: 524} {RNA1310_47413} {RNA815_29456.2} | |
75. | MligTC455_36286 | 2583 | 53.81 | Mlig455_049146 | Neo: - Age: Down-Down-Up Region-enriched R3: 6.207/0.00000 |
1.691 | - | - | - | 0.722 | 0.969 | - | Mlig455_049146 {REF} {Length: 746} {Pfam: CUB domain [PF00431.22, score=28.0]} {RNA1509_1672} {RNA1310_53620, RNA1509_1672} {RNA1509_1672, RNA815_26829} | |
76. | MligTC455_14583 | 33 | 0.69 | Mlig455_008303, Mlig455_008334 | Neo: - Age: - |
ADAM33, ADAM9 | 1.686 | - | - | - | 0.721 | - | 0.965 | Mlig455_008303 {REF} {Length: 2620} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=143.0]; Metallo-peptidase family M12 [PF13688.8, score=76.4]; Disintegrin [PF00200.25, score=72.2]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=45.7]; ADAM cysteine-rich [PF08516.14, score=45.0]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=41.2]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=37.2]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=249, Expect=1e-71]; ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=242, Expect=7e-68]} {Mouse: ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [Score=258, Expect=4e-74]} {Dmel: FBgn0265140, Meltrin, [Score=273, Expect=1e-78]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=233, Expect=6e-65]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=201, Expect=1e-53]} {RNA1509_45880} {RNA1310_77182} {RNA815_37786} Mlig455_008334 {REF} {Length: 2763} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=125.2]; Disintegrin [PF00200.25, score=72.6]; Metallo-peptidase family M12 [PF13688.8, score=64.4]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=46.3]; ADAM cysteine-rich [PF08516.14, score=44.9]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=40.6]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=32.8]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=224, Expect=4e-63]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=221, Expect=1e-62]; ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=219, Expect=7e-61]; ENSG00000134007, ADAM20, ADAM metallopeptidase domain 20, [Score=216, Expect=2e-60]; ENSG00000143537, ADAM15, ADAM metallopeptidase domain 15, [Score=215, Expect=5e-60]} {Mouse: ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [Score=229, Expect=6e-65]; ENSMUSG00000054555, Adam12, a disintegrin and metallopeptidase domain 12 (meltrin alpha), [Score=221, Expect=5e-62]; ENSMUSG00000025473, Adam8, a disintegrin and metallopeptidase domain 8, [Score=219, Expect=6e-62]} {Dmel: FBgn0265140, Meltrin, [Score=247, Expect=7e-71]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=218, Expect=7e-61]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=194, Expect=2e-52]} {RNA1509_45880} {RNA1310_77182} {RNA815_1440.1} |
77. | MligTC455_43728 | 1742 | 36.29 | Mlig455_031260 | Neo: - Age: Down-Down-Down, logFC(26M/2M)=-1.389 Region-enriched R3: 7.314/0.00000 |
1.681 | - | - | - | 0.703 | 0.978 | - | Mlig455_031260 {REF} {Length: 660} {RNA1509_4671} {RNA1310_89218} {RNA815_13649.1} | |
78. | MligTC455_43729 | 1693 | 35.28 | Mlig455_031321 | Neo: - Age: Down-Down-Up, logFC(26M/2M)=-0.820 Region-enriched R3: 7.339/0.00000 |
1.677 | - | - | - | 0.701 | 0.976 | - | Mlig455_031321 {REF} {Length: 727} {RNA1509_14236, RNA1509_25603, RNA1509_4671} {RNA1310_89218, RNA1509_14236, RNA1509_25603} {RNA1509_14236, RNA1509_25603, RNA815_13649.1} | |
79. | MligTC455_47737 | 3850 | 80.21 | Mlig455_057642, Mlig455_060148 | Neo: - Age: - Region-enriched R3: 5.960/0.00000 |
1.671 | - | - | - | 0.711 | 0.960 | - | Mlig455_057642 {REF} {Length: 1075} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=81.5]} {RNA1509_32190, RNA1509_39145, RNA1509_51431} {RNA1310_40941.1, RNA1509_32190, RNA1509_39145} {RNA1509_32190, RNA1509_39145, RNA815_34286.1} Mlig455_060148 {REF} {Length: 1301} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=122.2]} {RNA1509_39145} {RNA1310_40941.1} {RNA815_34286.1} |
|
80. | MligTC455_47221 | 2304 | 47.99 | Mlig455_053054 | Neo: - Age: - |
PCSK4 | 1.669 | - | - | - | 0.719 | 0.950 | - | Mlig455_053054 {REF} {Length: 2790} {Pfam: Subtilase family [PF00082.24, score=113.4]; Proprotein convertase P-domain [PF01483.22, score=45.5]} {Human: ENSG00000115257, PCSK4, proprotein convertase subtilisin/kexin type 4, [Score=304, Expect=1e-94]} {Mouse: ENSMUSG00000020131, Pcsk4, proprotein convertase subtilisin/kexin type 4, [Score=290, Expect=1e-90]; ENSMUSG00000024713, Pcsk5, proprotein convertase subtilisin/kexin type 5, [Score=288, Expect=3e-85]; ENSMUSG00000030530, Furin, furin (paired basic amino acid cleaving enzyme), [Score=280, Expect=2e-85]} {Dmel: FBgn0004509, Fur1, Furin 1, [Score=266, Expect=7e-80]} {Celegans: WBGene00002232, kpc-1, Furin-like protease kpc-1, [Score=301, Expect=1e-94]} {Smed: dd_Smed_v6_8406_0_2, dd_Smed_v6_8406_0_2, [Score=264, Expect=3e-81]} {RNA1509_21248, RNA1509_3476} {RNA1310_9937, RNA1509_21248} {RNA1509_21248, RNA815_2907} |
81. | MligTC455_19254 | 90 | 1.88 | Mlig455_004591 | Neo: - Age: - |
1 | - | - | - | - | 1.000 | - | Mlig455_004591 {REF} {Length: 710} {RNA1509_31473} {RNA1310_57601} {RNA815_20563} | |
82. | MligTC455_10353 | 3 | 0.06 | Mlig455_056181 | Neo: - |
STOM | 0.997 | - | - | - | - | 0.997 | - | Mlig455_056181 {REF} {Length: 2762} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=115.3]; SPFH domain-Band 7 family [PF13421.8, score=21.1]} {Human: ENSG00000148175, STOM, stomatin, [RH, Score=360, Expect=7e-125]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [RH, Score=351, Expect=8e-122]} {Dmel: FBgn0260657, CG42540, [Score=363, Expect=2e-123]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [RH, Score=385, Expect=1e-133]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [RH, Score=433, Expect=2e-154]} {RNA1509_58730} {RNA1310_19440.1, RNA1509_58730} {RNA1509_58730, RNA815_9049.1} |
83. | MligTC455_20112 | 2 | 0.04 | Mlig455_028978 | Neo: - Age: - |
IGSF9 | 0.997 | - | - | - | - | 0.997 | - | Mlig455_028978 {REF} {Length: 3575} {Pfam: Immunoglobulin domain [PF13927.8, score=128.1]; Immunoglobulin I-set domain [PF07679.18, score=87.9]; Immunoglobulin domain [PF13895.8, score=82.0]; Immunoglobulin domain [PF00047.27, score=71.2]; Immunoglobulin V-set domain [PF07686.19, score=67.0]; Fibronectin type III domain [PF00041.23, score=35.3]; Izumo-like Immunoglobulin domain [PF16706.7, score=26.8]; Immunoglobulin domain [PF18452.3, score=21.8]} {Human: ENSG00000085552, IGSF9, immunoglobulin superfamily member 9, [Score=144, Expect=2e-34]; ENSG00000080854, IGSF9B, immunoglobulin superfamily member 9B, [Score=139, Expect=1e-32]} {Mouse: ENSMUSG00000037995, Igsf9, immunoglobulin superfamily, member 9, [Score=144, Expect=1e-34]} {Dmel: FBgn0028482, bdl, borderless, [Score=122, Expect=2e-28]} {Celegans: WBGene00020130, igcm-2, ImmunoGlobulin-like Cell adhesion Molecule family, [Score=138, Expect=2e-33]} {Smed: dd_Smed_v6_17743_0_1, dd_Smed_v6_17743_0_1, [Score=142, Expect=2e-34]} {RNA1310_20896} {RNA815_31205} |
84. | MligTC455_16837 | 11 | 0.24 | Mlig455_030150 | Neo: - Age: - |
0.995 | - | - | - | - | 0.995 | - | Mlig455_030150 {REF} {Length: 1228} {RNA1310_40798} {RNA815_26160} | |
85. | MligTC455_12683 | 4 | 0.08 | Mlig455_013681 | Neo: - Age: - |
CASKIN1 | 0.994 | - | - | - | - | 0.994 | - | Mlig455_013681 {REF} {Length: 1211} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=125.4]; Ankyrin repeats (many copies) [PF13637.8, score=124.7]; Ankyrin repeat [PF00023.32, score=101.7]; Ankyrin repeats (many copies) [PF13857.8, score=98.5]; Ankyrin repeat [PF13606.8, score=97.6]} {Human: ENSG00000167971, CASKIN1, CASK interacting protein 1, [Score=174, Expect=4e-47]; ENSG00000177303, CASKIN2, CASK interacting protein 2, [Score=172, Expect=2e-46]} {Mouse: ENSMUSG00000033597, Caskin1, CASK interacting protein 1, [Score=174, Expect=2e-47]; ENSMUSG00000034471, Caskin2, CASK-interacting protein 2, [Score=169, Expect=1e-45]} {Dmel: FBgn0039075, CG4393, [Score=122, Expect=1e-29]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=102, Expect=4e-23]} {Smed: dd_Smed_v6_2072_0_26, dd_Smed_v6_2072_0_26, [Score=110, Expect=4e-26]} {RNA1310_1281} |
86. | MligTC455_52730 | 38 | 0.79 | Mlig455_070287 | Neo: - Age: - |
PRKCB | 0.993 | - | - | - | - | 0.993 | - | Mlig455_070287 {REF} {Length: 3656} {Pfam: Protein kinase domain [PF00069.27, score=223.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=132.1]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=116.7]; C2 domain [PF00168.32, score=103.6]; Protein kinase C terminal domain [PF00433.26, score=33.3]; C1 domain [PF03107.18, score=21.6]} {Human: ENSG00000166501, PRKCB, protein kinase C beta, [RH, Score=993, Expect=0.0]; ENSG00000154229, PRKCA, protein kinase C alpha, [RH, Score=969, Expect=0.0]} {Mouse: ENSMUSG00000052889, Prkcb, protein kinase C, beta, [RH, Score=992, Expect=0.0]; ENSMUSG00000050965, Prkca, protein kinase C, alpha, [RH, Score=972, Expect=0.0]} {Dmel: FBgn0003091, Pkc53E, Protein C kinase 53E, [RH, Score=967, Expect=0.0]} {Celegans: WBGene00004033, pkc-2, Protein kinase C-like 2, [RH, Score=952, Expect=0.0]} {Smed: dd_Smed_v6_4244_0_2, dd_Smed_v6_4244_0_2, [RH, Score=1057, Expect=0.0]} {RNA1509_44778} {RNA1310_40887} {RNA815_2012.1} |
87. | MligTC455_07277 | 53 | 1.1 | Mlig455_011764 | Neo: - Age: Down-Up-Down |
CHTF8 | 0.992 | - | - | - | - | 0.992 | - | Mlig455_011764 {REF} {Length: 560} {TRANSSPLICED} {Pfam: Ctf8 [PF09696.12, score=31.4]} {Human: ENSG00000168802, CHTF8, chromosome transmission fidelity factor 8, [RH, Score=73.2, Expect=3e-17]} {Mouse: ENSMUSG00000046691, Chtf8, CTF8, chromosome transmission fidelity factor 8, [RH, Score=75.1, Expect=4e-18]} {Dmel: FBgn0054001, CG34001, [RH, Score=69.7, Expect=8e-16]} {Celegans: WBGene00011915, T22C1.4, [RH, Score=43.9, Expect=2e-06]} {Smed: dd_Smed_v6_15527_0_1, dd_Smed_v6_15527_0_1, [RH, Score=59.3, Expect=2e-12]} {RNA1509_6270} {RNA1310_2848.1} {RNA815_4953.1} |
88. | MligTC455_09328 | 39 | 0.8 | Mlig455_032045 | Neo: - |
0.99 | - | - | - | - | 0.990 | - | Mlig455_032045 {REF} {Length: 2583} {Pfam: Domain of unknown function (DUF4010) [PF13194.8, score=20.4]} {RNA1310_46777} {RNA815_42352} | |
89. | MligTC455_33983 | 103 | 2.15 | Mlig455_013705, Mlig455_013722, Mlig455_013724 | Neo: - Age: - Region-enriched R4: 10.836/0.00000 |
0.988 | - | - | - | - | 0.988 | - | Mlig455_013705 {REF} {Length: 1120} {RNA1310_17183} {RNA815_21186} Mlig455_013722 {REF} {Length: 2283} {RNA1310_17183} {RNA815_21186} Mlig455_013724 {REF} {Length: 1641} {RNA1310_17183} {RNA815_21186} |
|
90. | MligTC455_10153 | 61 | 1.27 | Mlig455_068250, Mlig455_068270 | Neo: - Age: - |
ERBB4 | 0.987 | - | - | - | - | 0.987 | - | Mlig455_068250 {REF} {Length: 5331} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=269.3]; Protein kinase domain [PF00069.27, score=110.9]; Receptor L domain [PF01030.26, score=51.2]; Growth factor receptor domain IV [PF14843.8, score=47.2]; Furin-like cysteine rich region [PF00757.22, score=45.7]} {Human: ENSG00000178568, ERBB4, erb-b2 receptor tyrosine kinase 4, [Score=307, Expect=1e-85]; ENSG00000146648, EGFR, epidermal growth factor receptor, [Score=296, Expect=1e-82]} {Mouse: ENSMUSG00000062209, Erbb4, erb-b2 receptor tyrosine kinase 4, [Score=309, Expect=2e-86]; ENSMUSG00000020122, Egfr, epidermal growth factor receptor, [Score=295, Expect=4e-82]} {Dmel: FBgn0003731, Egfr, Epidermal growth factor receptor, [Score=311, Expect=7e-87]} {Celegans: WBGene00002299, let-23, Receptor tyrosine-protein kinase let-23, [Score=209, Expect=2e-54]} {Smed: dd_Smed_v6_11310_0_1, dd_Smed_v6_11310_0_1, [Score=303, Expect=3e-84]} {RNA1509_1271} {RNA1310_65071} {RNA815_42809} Mlig455_068270 {REF} {Length: 5369} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=271.6]; Protein kinase domain [PF00069.27, score=111.6]} {Human: ENSG00000178568, ERBB4, erb-b2 receptor tyrosine kinase 4, [Score=303, Expect=3e-89]; ENSG00000146648, EGFR, epidermal growth factor receptor, [Score=293, Expect=7e-86]} {Mouse: ENSMUSG00000062209, Erbb4, erb-b2 receptor tyrosine kinase 4, [Score=305, Expect=4e-90]; ENSMUSG00000020122, Egfr, epidermal growth factor receptor, [Score=291, Expect=2e-85]} {Dmel: FBgn0003731, Egfr, Epidermal growth factor receptor, [Score=288, Expect=5e-84]} {Celegans: WBGene00002299, let-23, Receptor tyrosine-protein kinase let-23, [Score=207, Expect=3e-56]} {Smed: dd_Smed_v6_11310_0_1, dd_Smed_v6_11310_0_1, [Score=300, Expect=5e-88]} {RNA1509_1271} {RNA1310_65071} {RNA815_42809} |
91. | MligTC455_00360 | 3 | 0.06 | Mlig455_003350 | Neo: - Age: - |
0.986 | - | - | - | - | 0.986 | - | Mlig455_003350 {REF} {Length: 572} {NoTransDecoderORF} {RNA1509_37106} {RNA1310_20119} {RNA815_32661} | |
92. | MligTC455_00893 | 1 | 0.02 | Mlig455_044599 | Neo: - Age: - |
CUBN | 0.986 | - | - | - | - | 0.986 | - | Mlig455_044599 {REF} {Length: 872} {Pfam: CUB domain [PF00431.22, score=55.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=58.2, Expect=3e-09]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=53.1, Expect=9e-08]} {Smed: dd_Smed_v6_69474_0_1, dd_Smed_v6_69474_0_1, [Score=44.3, Expect=3e-06]} {RNA1310_66805} |
93. | MligTC455_01855 | 5 | 0.1 | Mlig455_019884 | Neo: Germline Age: - |
0.986 | - | - | - | - | 0.986 | - | Mlig455_019884 {REF} {Length: 837} {RNA1310_46030.1} {RNA815_34666} | |
94. | MligTC455_01972 | 8 | 0.17 | Mlig455_065411 | Neo: - Age: - |
0.986 | - | - | - | - | 0.986 | - | Mlig455_065411 {REF} {Length: 646} {RNA1310_149608} | |
95. | MligTC455_02383 | 3 | 0.07 | Mlig455_006775 | Neo: - Age: - |
0.986 | - | - | - | - | 0.986 | - | Mlig455_006775 {REF} {Length: 1124} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=95.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=86.3]; Aspartyl protease [PF13650.8, score=20.6]; gag-polyprotein putative aspartyl protease [PF13975.8, score=19.6]} {Smed: dd_Smed_v6_15498_0_18, dd_Smed_v6_15498_0_18, [Score=79.3, Expect=2e-16]} {RNA1509_44038} {RNA1310_11212} {RNA815_45036} | |
96. | MligTC455_03210 | 1 | 0.02 | Mlig455_026190 | Neo: - Age: - |
0.986 | - | - | - | - | 0.986 | - | Mlig455_026190 {REF} {Length: 673} {NoTransDecoderORF} | |
97. | MligTC455_03368 | 10 | 0.21 | Mlig455_056536 | Neo: - Age: - |
HTR3A | 0.986 | - | - | - | - | 0.986 | - | Mlig455_056536 {REF} {Length: 1346} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=109.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=82.9]} {Human: ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=132, Expect=1e-33]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=126, Expect=1e-31]} {Mouse: ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=137, Expect=3e-35]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=122, Expect=5e-30]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=137, Expect=2e-35]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=126, Expect=1e-31]} {RNA1509_7752} {RNA1310_1750.2} {RNA815_6234} |
98. | MligTC455_03483 | 14 | 0.29 | Mlig455_004066, Mlig455_004118, Mlig455_060442 | Neo: - |
0.986 | - | - | - | - | 0.986 | - | Mlig455_004066 {REF} {Length: 399} {NoTransDecoderORF} {RNA1509_9966} {RNA1310_27634} {RNA815_4490.1} Mlig455_004118 {REF} {Length: 567} {NoTransDecoderORF} {RNA1509_9966} {RNA1310_12692.1} {RNA815_4490.1} Mlig455_060442 {REF} {Length: 536} {NoTransDecoderORF} {RNA1509_9966} {RNA1310_12692.1} {RNA815_4490.1} |
|
99. | MligTC455_04465 | 2 | 0.04 | Mlig455_019145 | Neo: - Age: - |
0.986 | - | - | - | - | 0.986 | - | Mlig455_019145 {REF} {Length: 352} {NoTransDecoderORF} {RNA1310_89330} | |
100. | MligTC455_04679 | 2 | 0.04 | Mlig455_058054 | Neo: - Age: Up-Down-Down |
0.986 | - | - | - | - | 0.986 | - | Mlig455_058054 {REF} {Length: 1496} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=50.2]} {Smed: dd_Smed_v6_9783_0_1, dd_Smed_v6_9783_0_1, [Score=92.4, Expect=1e-20]} {RNA1509_4484} {RNA1310_25467} {RNA815_39314} |