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Results for MligTC455_41907

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_41907 14 0.30 Mlig455_020658

Neo: -

Age: Up-Down-Down

 CADPS Mlig455_020658 {REF} {Length: 4466} {TRANSSPLICED} {Pfam: MUN domain [PF06292.19, score=403.4]; PH domain [PF00169.31, score=33.8]; C2 domain [PF00168.32, score=20.9]} {Human: ENSG00000163618, CADPS, calcium dependent secretion activator, [Score=1257, Expect=0.0]; ENSG00000081803, CADPS2, calcium dependent secretion activator 2, [Score=1224, Expect=0.0]} {Mouse: ENSMUSG00000054423, Cadps, Ca2+-dependent secretion activator, [Score=1243, Expect=0.0]; ENSMUSG00000017978, Cadps2, Ca2+-dependent activator protein for secretion 2, [Score=1224, Expect=0.0]} {Dmel: FBgn0053653, Cadps, Calcium-dependent secretion activator, [Score=1279, Expect=0.0]} {Celegans: WBGene00006767, unc-31, Calcium-dependent secretion activator, [Score=1090, Expect=0.0]} {Smed: dd_Smed_v6_11725_0_1, dd_Smed_v6_11725_0_1, [Score=1281, Expect=0.0]} {RNA1509_26708} {RNA1310_4475, RNA1509_26708} {RNA1509_26708, RNA815_2341}

Cumulative graph for MligTC455_41907

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.057 0.795 1.00000 1.00000
RegionR2 -2.448 0.795 1.00000 1.00000
RegionR3 -1.464 0.795 0.99971 1.00000
RegionR4 5.803 0.795 0.01871 0.09723
RegionR5 2.026 0.795 0.16692 0.43315
RegionR6 -1.512 0.795 1.00000 1.00000
RegionR7 -1.465 0.795 0.99972 1.00000
RegionR8 -0.997 0.795 1.00000 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.795 0.795 1.00000 1.00000
RegenerationR2 0.62 0.795 0.65860 0.94061
RegenerationR3 1.969 0.795 0.91641 1.00000
RegenerationR4 -4.028 0.795 0.07633 0.43959
RegenerationR5 -0.361 0.795 0.36274 0.77385
RegenerationR6 -1.402 0.795 0.99986 1.00000
RegenerationBL -0.924 0.795 1.00000 1.00000
RegenerationTP -1.512 0.795 0.99966 1.00000


Genes with expression patterns similar to MligTC455_41907

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_41907 14 0.3 Mlig455_020658

Neo: -

Age: Up-Down-Down

 CADPS 3 - - 1.000 - 1.000 1.000 Mlig455_020658 {REF} {Length: 4466} {TRANSSPLICED} {Pfam: MUN domain [PF06292.19, score=403.4]; PH domain [PF00169.31, score=33.8]; C2 domain [PF00168.32, score=20.9]} {Human: ENSG00000163618, CADPS, calcium dependent secretion activator, [Score=1257, Expect=0.0]; ENSG00000081803, CADPS2, calcium dependent secretion activator 2, [Score=1224, Expect=0.0]} {Mouse: ENSMUSG00000054423, Cadps, Ca2+-dependent secretion activator, [Score=1243, Expect=0.0]; ENSMUSG00000017978, Cadps2, Ca2+-dependent activator protein for secretion 2, [Score=1224, Expect=0.0]} {Dmel: FBgn0053653, Cadps, Calcium-dependent secretion activator, [Score=1279, Expect=0.0]} {Celegans: WBGene00006767, unc-31, Calcium-dependent secretion activator, [Score=1090, Expect=0.0]} {Smed: dd_Smed_v6_11725_0_1, dd_Smed_v6_11725_0_1, [Score=1281, Expect=0.0]} {RNA1509_26708} {RNA1310_4475, RNA1509_26708} {RNA1509_26708, RNA815_2341}
2. MligTC455_38556 168 3.5 Mlig455_049546

Neo: -

Age: logFC(26M/2M)=-0.547

Region-enriched R3: 4.481/0.00055

 AMY1C 1.66 - - 0.703 - 0.957 - Mlig455_049546 {REF} {Length: 2273} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=54.2]; Alpha amylase, C-terminal all-beta domain [PF02806.20, score=41.8]} {Human: ENSG00000187733, AMY1C, amylase, alpha 1C (salivary), [RH, Score=592, Expect=0.0]; ENSG00000237763, AMY1A, amylase, alpha 1A (salivary), [RH, Score=592, Expect=0.0]; ENSG00000174876, AMY1B, amylase, alpha 1B (salivary), [RH, Score=592, Expect=0.0]; ENSG00000240038, AMY2B, amylase, alpha 2B (pancreatic), [RH, Score=591, Expect=0.0]; ENSG00000243480, AMY2A, amylase, alpha 2A (pancreatic), [RH, Score=588, Expect=0.0]} {Mouse: ENSMUSG00000074264, Amy1, amylase 1, salivary, [RH, Score=584, Expect=0.0]; ENSMUSG00000096770, Amy2a4, amylase 2a4, [RH, Score=575, Expect=0.0]; ENSMUSG00000096569, Amy2a2, amylase 2a2, [RH, Score=575, Expect=0.0]; ENSMUSG00000093931, Amy2a3, amylase 2a3, [RH, Score=575, Expect=0.0]; ENSMUSG00000074268, Amy2a5, amylase 2a5, [RH, Score=575, Expect=0.0]} {Dmel: FBgn0000078, Amy-d, Amylase distal, [RH, Score=492, Expect=5e-171]} {Celegans: WBGene00008220, C50B6.7, Alpha-amylase, [Score=359, Expect=2e-116]} {RNA1509_1421} {RNA1310_11165, RNA1509_1421} {RNA1509_1421, RNA815_3708.1}
3. MligTC455_02266 8 0.16 Mlig455_069150

Neo: -

Age: -

 1 - - - - 1.000 - Mlig455_069150 {REF} {Length: 532} {RNA1509_43209} {RNA1310_129145} {RNA815_24538}
4. MligTC455_06444 29 0.61 Mlig455_009655

Neo: -

Age: -

 1 - - - - 1.000 - Mlig455_009655 {REF} {Length: 2004} {RNA1310_35837.1} {RNA815_50334}
5. MligTC455_24311 5 0.1 Mlig455_040354

Neo: -

Age: -

 1 - - - - 1.000 - Mlig455_040354 {REF} {Length: 526} {NoTransDecoderORF} {RNA1310_89152} {RNA815_41473}
6. MligTC455_38173 4 0.09 Mlig455_041306

Neo: -

Age: Up-Down-Down

 DNAH17 0.999 - - - - 0.999 - Mlig455_041306 {REF} {Length: 2376} {Pfam: Dynein heavy chain C-terminal domain [PF18199.3, score=349.5]; Dynein heavy chain AAA lid domain [PF18198.3, score=175.6]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=131.3]} {Human: ENSG00000187775, DNAH17, dynein axonemal heavy chain 17, [Score=1108, Expect=0.0]; ENSG00000007174, DNAH9, dynein axonemal heavy chain 9, [Score=1103, Expect=0.0]} {Mouse: ENSMUSG00000033987, Dnah17, dynein, axonemal, heavy chain 17, [Score=1120, Expect=0.0]; ENSMUSG00000056752, Dnah9, dynein, axonemal, heavy chain 9, [Score=1097, Expect=0.0]} {Dmel: FBgn0013812, Dhc93AB, Dynein heavy chain at 93AB, [Score=1077, Expect=0.0]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=212, Expect=1e-57]} {Smed: dd_Smed_v6_3670_0_1, dd_Smed_v6_3670_0_1, [Score=1254, Expect=0.0]} {RNA1509_140} {RNA1310_286} {RNA815_831}
7. MligTC455_02760 16 0.32 Mlig455_019892

Neo: -

Age: -

 0.998 - - - - 0.998 - Mlig455_019892 {REF} {Length: 2308} {NoTransDecoderORF}
8. MligTC455_05930 7 0.14 Mlig455_024449

Neo: -

Age: -

 0.998 - - - - 0.998 - Mlig455_024449 {REF} {Length: 721} {RNA1310_116165}
9. MligTC455_26982 6 0.13 Mlig455_012994

Neo: -

Age: -

 ANKRD50 0.991 - - - - 0.991 - Mlig455_012994 {REF} {Length: 5592} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=123.6]; Ankyrin repeat [PF00023.32, score=81.6]; Ankyrin repeats (many copies) [PF13857.8, score=78.7]; Ankyrin repeats (many copies) [PF13637.8, score=75.9]; Ankyrin repeat [PF13606.8, score=69.3]; Mab-21 protein [PF03281.16, score=35.4]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=85.9, Expect=4e-16]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=84.3, Expect=9e-16]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=80.1, Expect=1e-14]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=64.7, Expect=5e-10]} {Smed: dd_Smed_v6_4322_0_1, dd_Smed_v6_4322_0_1, [Score=67.0, Expect=6e-11]} {RNA1509_2705} {RNA1310_4888.2} {RNA815_10746}
10. MligTC455_01018 4 0.07 Mlig455_020251

Neo: -

Age: -

 0.99 - - - - 0.990 - Mlig455_020251 {REF} {Length: 428} {NoTransDecoderORF} {RNA1310_50543}
11. MligTC455_06763 10 0.21 Mlig455_010608

Neo: -

Age: -

 0.99 - - - - 0.990 - Mlig455_010608 {REF} {Length: 981} {NoTransDecoderORF} {RNA1509_21079} {RNA1310_142796}
12. MligTC455_44707 2674 55.7 Mlig455_060882

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=3.903

Region-enriched R3: 5.097/0.00000

 TLL1 0.99 - - - - 0.990 - Mlig455_060882 {REF} {Length: 934} {Pfam: Astacin (Peptidase family M12A) [PF01400.26, score=170.1]} {Human: ENSG00000038295, TLL1, tolloid like 1, [Score=118, Expect=9e-31]; ENSG00000188886, ASTL, astacin like metalloendopeptidase, [Score=117, Expect=5e-30]; ENSG00000141434, MEP1B, meprin A subunit beta, [Score=115, Expect=1e-28]; ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=114, Expect=1e-28]} {Mouse: ENSMUSG00000053626, Tll1, tolloid-like, [Score=119, Expect=3e-30]; ENSMUSG00000024313, Mep1b, meprin 1 beta, [Score=117, Expect=1e-29]; ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=114, Expect=1e-28]} {Dmel: FBgn0028948, CG15253, [RH, Score=152, Expect=2e-45]} {Celegans: WBGene00003523, nas-4, Zinc metalloproteinase nas-4, [Score=129, Expect=5e-36]} {Smed: dd_Smed_v6_961_0_1, dd_Smed_v6_961_0_1, [Score=109, Expect=4e-29]} {RNA1509_58597} {RNA1310_40274} {RNA815_19279.1}
13. MligTC455_56713 3 0.07 Mlig455_000328

Neo: -

Age: -

 0.99 - - - - 0.990 - Mlig455_000328 {REF} {Length: 393} {NoTransDecoderORF}
14. MligTC455_10659 3 0.05 Mlig455_021883

Neo: -

Age: -

 0.988 - - - - 0.988 - Mlig455_021883 {REF} {Length: 232} {NoTransDecoderORF} {RNA1310_77982} {RNA815_38187}
15. MligTC455_25289 6532 136.09 Mlig455_038419

Neo: -

Age: Down-Up-Up

Region-specific R3: 6.513

Region-enriched R3: 6.333/0.00000

 TNN 0.987 - - - - 0.987 - Mlig455_038419 {REF} {Length: 1476} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=129.4]} {Human: ENSG00000120332, TNN, tenascin N, [Score=120, Expect=4e-29]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=119, Expect=5e-29]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=116, Expect=3e-28]} {Mouse: ENSMUSG00000026725, Tnn, tenascin N, [Score=124, Expect=3e-30]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=120, Expect=1e-29]; ENSMUSG00000026938, Fcna, ficolin A, [Score=119, Expect=4e-30]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=119, Expect=2e-29]} {Dmel: FBgn0051832, CG31832, [Score=105, Expect=4e-26]} {Celegans: WBGene00020516, T15B7.1, [Score=66.2, Expect=8e-12]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=85.9, Expect=5e-18]} {RNA1509_45498, RNA1509_740} {RNA1310_24610.1, RNA1509_45498, RNA1509_740} {RNA1509_45498, RNA1509_740, RNA815_8978.2}
16. MligTC455_34879 33 0.68 Mlig455_006955

Neo: -

Age: Up-Down-Down

 0.986 - - - - 0.986 - Mlig455_006955 {REF} {Length: 5084} {RNA1509_31973} {RNA1310_5137.1} {RNA815_39446}
17. MligTC455_33936 62 1.29 Mlig455_061181

Neo: -

Age: Down-Down-Up

Region-enriched R3: 4.766/0.00000

 0.985 - - - - 0.985 - Mlig455_061181 {REF} {Length: 2443} {Pfam: Fibronectin type II domain [PF00040.21, score=54.5]} {Mouse: ENSMUSG00000054580, Pla2r1, phospholipase A2 receptor 1, [Score=50.1, Expect=2e-06]} {RNA1310_23349.1} {RNA815_44226.1}
18. MligTC455_36331 1502 31.28 Mlig455_013523, Mlig455_013524, Mlig455_061355, Mlig455_061362

Neo: -

Age: logFC(26M/2M)=1.048

Region-specific R3: 5.547

Region-enriched R3: 6.000/0.00000

 KREMEN2 0.982 - - - - 0.982 -

Mlig455_013523 {REF} {Length: 404} {Pfam: F5/8 type C domain [PF00754.27, score=62.5]; Small zinc finger protein HVO_2753-like, Zn-binding pocket [PF07754.13, score=19.8]} {Smed: dd_Smed_v6_52492_0_1, dd_Smed_v6_52492_0_1, [Score=52.4, Expect=5e-08]} {RNA1509_2195} {RNA1310_4987.1} {RNA815_612.1}

Mlig455_013524 {REF} {Length: 932} {Pfam: F5/8 type C domain [PF00754.27, score=31.2]} {Smed: dd_Smed_v6_52492_0_1, dd_Smed_v6_52492_0_1, [Score=52.0, Expect=2e-08]} {RNA1509_21733} {RNA1310_11857} {RNA815_612.1}

Mlig455_061355 {REF} {Length: 1985} {Pfam: F5/8 type C domain [PF00754.27, score=62.5]; Small zinc finger protein HVO_2753-like, Zn-binding pocket [PF07754.13, score=19.8]} {Smed: dd_Smed_v6_52492_0_1, dd_Smed_v6_52492_0_1, [Score=52.4, Expect=5e-08]} {RNA1509_21733} {RNA1310_11857} {RNA815_612.1}

Mlig455_061362 {REF} {Length: 6001} {Pfam: F5/8 type C domain [PF00754.27, score=149.8]; WSC domain [PF01822.21, score=62.9]; Clip-domain serine protease homolog Scarface [PF18399.3, score=38.7]; Phostensin PP1-binding and SH3-binding region [PF13914.8, score=28.9]; Influenza A Proapoptotic protein [PF11986.10, score=22.3]; NgoBV restriction endonuclease [PF09564.12, score=20.4]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [RH, Score=66.2, Expect=3e-10]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [RH, Score=65.5, Expect=4e-10]} {Smed: dd_Smed_v6_52492_0_1, dd_Smed_v6_52492_0_1, [Score=56.2, Expect=6e-09]} {RNA1509_15294, RNA1509_21733} {RNA1310_11815, RNA1509_21733} {RNA1509_21733, RNA815_612.1}
19. MligTC455_21798 400 8.34 Mlig455_030373

Neo: -

Age: Up-Down-Down

Region-specific R3: 7.095

Region-enriched R3: 6.951/0.00000

 HMCN2 0.978 - - - - 0.978 - Mlig455_030373 {REF} {Length: 4938} {Pfam: WSC domain [PF01822.21, score=501.5]; von Willebrand factor type A domain [PF13519.8, score=70.0]; LCCL domain [PF03815.21, score=47.0]; von Willebrand factor type A domain [PF13768.8, score=44.2]; Histone deacetylation protein Rxt3 [PF08642.12, score=23.7]} {Human: ENSG00000148357, HMCN2, hemicentin 2, [Score=78.6, Expect=1e-13]; ENSG00000143341, HMCN1, hemicentin 1, [Score=75.5, Expect=8e-13]; ENSG00000075035, WSCD2, WSC domain containing 2, [Score=75.5, Expect=5e-13]} {Mouse: ENSMUSG00000055632, Hmcn2, hemicentin 2, [Score=77.8, Expect=1e-13]; ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=77.0, Expect=9e-14]; ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=76.6, Expect=3e-13]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=57.8, Expect=8e-08]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=92.0, Expect=3e-18]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=93.2, Expect=1e-18]} {RNA1509_14078, RNA1509_51440} {RNA1310_11605.2, RNA1509_51440} {RNA1509_51440, RNA815_1633.1}
20. MligTC455_21799 403 8.4 Mlig455_030420

Neo: -

Age: Up-Down-Down

Region-specific R3: 6.931

Region-enriched R3: 6.913/0.00000

 HMCN2 0.978 - - - - 0.978 - Mlig455_030420 {REF} {Length: 1479} {Pfam: WSC domain [PF01822.21, score=113.5]; von Willebrand factor type A domain [PF13519.8, score=34.1]; von Willebrand factor type A domain [PF00092.30, score=27.0]; von Willebrand factor type A domain [PF13768.8, score=20.5]} {Human: ENSG00000148357, HMCN2, hemicentin 2, [Score=79.0, Expect=8e-15]; ENSG00000143341, HMCN1, hemicentin 1, [Score=75.1, Expect=1e-13]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=76.3, Expect=3e-14]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=73.9, Expect=9e-14]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=77.4, Expect=6e-15]} {RNA1509_14078, RNA1509_53874} {RNA1310_11605.2, RNA1509_53874} {RNA1509_53874, RNA815_1633.1}
21. MligTC455_12384 30 0.62 Mlig455_014121, Mlig455_014129

Neo: -

Age: -

Regeneration-downregulated R2: -5.903

Regeneration-depleted R2: -5.903

 MARK3, MARK4 0.977 - - - - 0.977 -

Mlig455_014121 {REF} {Length: 3626} {Pfam: Protein kinase domain [PF00069.27, score=234.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=140.0]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=28.3]; Kinase-like [PF14531.8, score=26.9]; ABC1 atypical kinase-like domain [PF03109.18, score=21.4]; Ternary complex associated domain 9 [PF19974.1, score=18.3]} {Human: ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=219, Expect=7e-60]; ENSG00000072518, MARK2, microtubule affinity regulating kinase 2, [Score=215, Expect=2e-58]; ENSG00000075413, MARK3, microtubule affinity regulating kinase 3, [Score=212, Expect=2e-57]} {Mouse: ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=217, Expect=4e-59]; ENSMUSG00000024969, Mark2, MAP/microtubule affinity regulating kinase 2, [Score=215, Expect=1e-58]; ENSMUSG00000007411, Mark3, MAP/microtubule affinity regulating kinase 3, [Score=213, Expect=1e-57]} {Dmel: FBgn0026063, KP78b, [Score=218, Expect=1e-60]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=220, Expect=5e-59]} {Smed: dd_Smed_v6_14823_0_1, dd_Smed_v6_14823_0_1, [Score=414, Expect=7e-133]} {RNA1310_41210} {RNA815_38347}

Mlig455_014129 {REF} {Length: 3531} {Pfam: Protein kinase domain [PF00069.27, score=107.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=69.2]} {Human: ENSG00000075413, MARK3, microtubule affinity regulating kinase 3, [Score=93.2, Expect=3e-19]} {Mouse: ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=86.7, Expect=3e-17]; ENSMUSG00000009772, Nuak2, NUAK family, SNF1-like kinase, 2, [Score=84.0, Expect=2e-16]; ENSMUSG00000024969, Mark2, MAP/microtubule affinity regulating kinase 2, [Score=83.2, Expect=4e-16]} {Dmel: FBgn0262103, Sik3, Salt-inducible kinase 3, [Score=87.4, Expect=2e-17]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=86.3, Expect=3e-17]} {Smed: dd_Smed_v6_14823_0_1, dd_Smed_v6_14823_0_1, [Score=151, Expect=1e-38]} {RNA1310_80369} {RNA815_38347}
22. MligTC455_10889 200 4.16 Mlig455_017218, Mlig455_048197

Neo: Germline

Age: -

Region-specific R4: 6.029

Region-enriched R4: 3.071/0.00130

 LPP, TRIP6 0.976 - - 0.976 - - -

Mlig455_017218 {REF} {Length: 1930} {Pfam: LIM domain [PF00412.24, score=35.1]} {Human: ENSG00000145012, LPP, LIM domain containing preferred translocation partner in lipoma, [Score=47.4, Expect=1e-05]} {Mouse: ENSMUSG00000023348, Trip6, thyroid hormone receptor interactor 6, [Score=47.0, Expect=1e-05]} {RNA1509_53902} {RNA1310_18696.1} {RNA815_17618}

Mlig455_048197 {REF} {Length: 1931} {Pfam: LIM domain [PF00412.24, score=49.4]} {Human: ENSG00000087077, TRIP6, thyroid hormone receptor interactor 6, [Score=61.6, Expect=1e-09]} {Mouse: ENSMUSG00000023348, Trip6, thyroid hormone receptor interactor 6, [Score=60.5, Expect=2e-09]} {RNA1509_53902} {RNA1310_18696.1} {RNA815_17618}
23. MligTC455_18221 376 7.84 Mlig455_040783, Mlig455_040836, Mlig455_064618

Neo: Germline

Age: -

Region-specific R4: 7.373

Region-enriched R4: 4.742/0.00012

 0.976 - - 0.976 - - -

Mlig455_040783 {REF} {Length: 873} {RNA1509_43061} {RNA1310_100464} {RNA815_25180}

Mlig455_040836 {REF} {Length: 460} {RNA1509_43061} {RNA1310_100464} {RNA815_25180}

Mlig455_064618 {REF} {Length: 459} {RNA1509_37906, RNA1509_43061} {RNA1310_100464, RNA1509_37906, RNA1509_43061} {RNA1509_37906, RNA1509_43061, RNA815_25180}
24. MligTC455_45074 9 0.19 Mlig455_067112

Neo: -

Age: -

 ASIC5 0.976 - - - - 0.976 - Mlig455_067112 {REF} {Length: 2924} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=199.0]} {Human: ENSG00000256394, ASIC5, acid sensing ion channel subunit family member 5, [Score=63.5, Expect=9e-10]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=61.6, Expect=2e-09]} {Celegans: WBGene00010278, F58G6.8, [Score=56.6, Expect=6e-09]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [RH, Score=441, Expect=1e-145]} {RNA1509_30695} {RNA1310_7174.1} {RNA815_3961}
25. MligTC455_45629 24 0.49 Mlig455_032109

Neo: -

Age: -

 0.976 - - - - 0.976 - Mlig455_032109 {REF} {Length: 788} {Pfam: Pancreatic hormone peptide [PF00159.20, score=28.0]} {RNA1509_59316} {RNA1310_91502} {RNA815_61453}
26. MligTC455_29796 153 3.19 Mlig455_010669, Mlig455_010764

Neo: -

Age: -

Region-enriched R3: 5.387/0.00000

 0.974 - - - - 0.974 -

Mlig455_010669 {REF} {Length: 1453} {NoTransDecoderORF} {RNA1509_450} {RNA1310_96673} {RNA815_20805}

Mlig455_010764 {REF} {Length: 97} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_450} {RNA1310_43615} {RNA815_20805}
27. MligTC455_12892 6 0.12 Mlig455_010510, Mlig455_061868

Neo: -

Age: -

 0.972 - - - - 0.972 -

Mlig455_010510 {REF} {Length: 421} {NoTransDecoderORF} {RNA1310_125495}

Mlig455_061868 {REF} {Length: 231} {NoTransDecoderORF} {RNA1310_125495}
28. MligTC455_08126 61 1.28 Mlig455_019453

Neo: Germline

Age: Up-Down-Down

Region-enriched R4: 4.567/0.00165

 0.971 - - 0.971 - - - Mlig455_019453 {REF} {Length: 620} {RNA1509_54069} {RNA1310_34680.2} {RNA815_15951}
29. MligTC455_20267 11467 238.9 Mlig455_009795, Mlig455_010377

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.495

Region-enriched R3: 1.040/0.00004

 EIF4EBP2 0.971 - - - - 0.971 -

Mlig455_009795 {REF} {Length: 1589} {TRANSSPLICED} {Pfam: Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) [PF05456.13, score=139.0]} {Human: ENSG00000148730, EIF4EBP2, eukaryotic translation initiation factor 4E binding protein 2, [RH, Score=107, Expect=4e-31]} {Mouse: ENSMUSG00000020091, Eif4ebp2, eukaryotic translation initiation factor 4E binding protein 2, [RH, Score=108, Expect=2e-31]} {Dmel: FBgn0261560, Thor, [RH, Score=73.9, Expect=3e-18]} {Smed: dd_Smed_v6_1204_0_1, dd_Smed_v6_1204_0_1, [RH, Score=85.1, Expect=6e-23]} {RNA1509_10337, RNA1509_27103, RNA1509_38027, RNA1509_47490, RNA1509_48163, RNA1509_58432} {RNA1310_20180.1, RNA1509_10337, RNA1509_27103, RNA1509_38027, RNA1509_47490, RNA1509_48163, RNA1509_58432} {RNA1509_10337, RNA1509_27103, RNA1509_38027, RNA1509_47490, RNA1509_48163, RNA1509_58432, RNA815_7917}

Mlig455_010377 {REF} {Length: 1592} {TRANSSPLICED} {Pfam: Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) [PF05456.13, score=139.0]} {Human: ENSG00000148730, EIF4EBP2, eukaryotic translation initiation factor 4E binding protein 2, [RH, Score=107, Expect=4e-31]} {Mouse: ENSMUSG00000020091, Eif4ebp2, eukaryotic translation initiation factor 4E binding protein 2, [RH, Score=108, Expect=2e-31]} {Dmel: FBgn0261560, Thor, [RH, Score=73.9, Expect=3e-18]} {Smed: dd_Smed_v6_1204_0_1, dd_Smed_v6_1204_0_1, [RH, Score=85.1, Expect=6e-23]} {RNA1509_27504, RNA1509_45764, RNA1509_48163, RNA1509_5688, RNA1509_59841} {RNA1310_20180.1, RNA1509_27504, RNA1509_45764, RNA1509_5688, RNA1509_59841} {RNA1509_27504, RNA1509_45764, RNA1509_5688, RNA1509_59841, RNA815_7917}
30. MligTC455_33080 814 16.95 Mlig455_049373

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.494

Region-specific R3: 6.455

Region-enriched R3: 6.051/0.00000

 FN1 0.97 - - - - 0.970 - Mlig455_049373 {REF} {Length: 1253} {Pfam: Fibronectin type II domain [PF00040.21, score=92.6]; Calcium-binding EGF domain [PF07645.17, score=30.5]} {Human: ENSG00000115414, FN1, fibronectin 1, [RH, Score=83.6, Expect=7e-18]} {Mouse: ENSMUSG00000026193, Fn1, fibronectin 1, [RH, Score=85.5, Expect=1e-18]} {Celegans: WBGene00007170, B0393.5, [Score=51.2, Expect=2e-07]} {Smed: dd_Smed_v6_14558_0_1, dd_Smed_v6_14558_0_1, [Score=52.0, Expect=5e-08]} {RNA1509_35441, RNA1509_9115} {RNA1310_32646.1, RNA1509_35441, RNA1509_9115} {RNA1509_35441, RNA1509_9115, RNA815_14924.1}
31. MligTC455_10268 5 0.11 Mlig455_016541, Mlig455_016598

Neo: -

Age: Down-Up-Down

 ANK3 0.969 - - - - 0.969 -

Mlig455_016541 {REF} {Length: 2799} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=58.3]; Ankyrin repeat [PF13606.8, score=55.6]; Ankyrin repeats (many copies) [PF13637.8, score=55.3]; Ankyrin repeats (many copies) [PF13857.8, score=51.9]; Ankyrin repeat [PF00023.32, score=42.9]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=66.6, Expect=5e-11]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=66.2, Expect=6e-11]; ENSG00000029534, ANK1, ankyrin 1, [Score=65.9, Expect=9e-11]; ENSG00000183475, ASB7, ankyrin repeat and SOCS box containing 7, [Score=63.9, Expect=1e-10]; ENSG00000170209, ANKK1, ankyrin repeat and kinase domain containing 1, [Score=63.9, Expect=3e-10]; ENSG00000107854, TNKS2, tankyrase 2, [Score=63.9, Expect=3e-10]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=69.7, Expect=3e-12]; ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=68.2, Expect=1e-11]} {Dmel: FBgn0035113, pyx, pyrexia, [Score=77.4, Expect=7e-15]} {Celegans: WBGene00019257, dhhc-13, Palmitoyltransferase, [Score=59.3, Expect=3e-09]} {Smed: dd_Smed_v6_7379_0_13, dd_Smed_v6_7379_0_13, [Score=61.6, Expect=7e-11]} {RNA1509_44381} {RNA1310_2160.1} {RNA815_6791}

Mlig455_016598 {REF} {Length: 3520} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=86.8]; Ankyrin repeats (many copies) [PF13637.8, score=70.1]; Ankyrin repeat [PF13606.8, score=54.9]; Ankyrin repeats (many copies) [PF13857.8, score=48.0]; Ankyrin repeat [PF00023.32, score=42.3]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=74.7, Expect=7e-13]; ENSG00000170921, TANC2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=71.2, Expect=6e-12]; ENSG00000145362, ANK2, ankyrin 2, [Score=71.2, Expect=8e-12]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=77.0, Expect=9e-14]; ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=73.2, Expect=1e-12]} {Dmel: FBgn0035113, pyx, pyrexia, [Score=78.2, Expect=2e-14]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=65.5, Expect=2e-10]} {Smed: dd_Smed_v6_8382_0_1, dd_Smed_v6_8382_0_1, [Score=145, Expect=3e-35]} {RNA1509_44381} {RNA1310_2160.1} {RNA815_6791}
32. MligTC455_19267 801 16.69 Mlig455_030283

Neo: -

Age: Down-Up-Up

Region-specific R3: 7.265

Region-enriched R3: 7.560/0.00000
Region-enriched R2: 3.641/0.04465

 0.968 - - - - 0.968 - Mlig455_030283 {REF} {Length: 1789} {Pfam: Fibronectin type II domain [PF00040.21, score=55.6]} {RNA1509_26955, RNA1509_33093} {RNA1310_16169, RNA1509_33093} {RNA1509_33093, RNA815_17685}
33. MligTC455_38018 3083 64.24 Mlig455_045082

Neo: -

Age: Up-Down-Down

Region-specific R3: 6.880

Region-enriched R3: 6.761/0.00000

 HMCN1 0.967 - - - - 0.967 - Mlig455_045082 {REF} {Length: 16670} {Pfam: Galactose binding lectin domain [PF02140.20, score=169.4]; von Willebrand factor type A domain [PF13519.8, score=37.4]; von Willebrand factor type A domain [PF00092.30, score=29.5]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=103, Expect=5e-21]; ENSG00000148357, HMCN2, hemicentin 2, [Score=102, Expect=9e-21]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=103, Expect=4e-21]} {Dmel: FBgn0033313, Cirl, Calcium-independent receptor for alpha-latrotoxin, [RH, Score=73.2, Expect=4e-12]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=85.1, Expect=6e-16]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=97.4, Expect=9e-20]} {RNA1509_18605, RNA1509_262} {RNA1310_79.1, RNA1509_18605} {RNA1509_18605, RNA815_38}
34. MligTC455_15966 5454 113.63 Mlig455_003058, Mlig455_003264, Mlig455_062835

Neo: -

Age: -

Region-specific R3: 6.443

Region-enriched R3: 6.417/0.00000

 LPA 0.966 - - - - 0.966 -

Mlig455_003058 {REF} {Length: 3386} {Pfam: F5/8 type C domain [PF00754.27, score=107.6]; Kringle domain [PF00051.20, score=41.3]; Fascin domain [PF06268.15, score=35.9]; Eukaryotic initiation factor 4E [PF01652.20, score=21.9]} {Human: ENSG00000198670, LPA, lipoprotein(a), [Score=55.5, Expect=3e-07]} {Mouse: ENSMUSG00000059481, Plg, plasminogen, [Score=56.2, Expect=1e-07]} {Smed: dd_Smed_v6_10257_0_1, dd_Smed_v6_10257_0_1, [Score=51.2, Expect=2e-06]} {RNA1509_1148} {RNA1310_4281.1} {RNA815_1448}

Mlig455_003264 {REF} {Length: 2972} {Pfam: F5/8 type C domain [PF00754.27, score=134.3]; Kringle domain [PF00051.20, score=40.8]; Fascin domain [PF06268.15, score=35.7]; Homotrimeric ring hydroxylase [PF11723.10, score=22.8]; Eukaryotic initiation factor 4E [PF01652.20, score=21.8]} {Human: ENSG00000198670, LPA, lipoprotein(a), [Score=55.5, Expect=4e-07]} {Mouse: ENSMUSG00000059481, Plg, plasminogen, [Score=56.2, Expect=2e-07]} {Smed: dd_Smed_v6_13385_0_1, dd_Smed_v6_13385_0_1, [Score=51.6, Expect=2e-06]} {RNA1509_1148} {RNA1310_4281.1} {RNA815_1448}

Mlig455_062835 {REF} {Length: 3978} {Pfam: F5/8 type C domain [PF00754.27, score=107.6]; Kringle domain [PF00051.20, score=41.3]; Fascin domain [PF06268.15, score=35.9]; Eukaryotic initiation factor 4E [PF01652.20, score=21.9]} {Human: ENSG00000198670, LPA, lipoprotein(a), [Score=55.5, Expect=3e-07]} {Mouse: ENSMUSG00000059481, Plg, plasminogen, [Score=56.2, Expect=1e-07]} {Smed: dd_Smed_v6_10257_0_1, dd_Smed_v6_10257_0_1, [Score=51.2, Expect=2e-06]} {RNA1509_1148, RNA1509_8252} {RNA1310_4281.1, RNA1509_8252} {RNA1509_8252, RNA815_1448}
35. MligTC455_36828 350 7.3 Mlig455_019540

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.696

Region-specific R3: 7.604

Region-enriched R3: 8.268/0.00000

 0.966 - - - - 0.966 - Mlig455_019540 {REF} {Length: 632} {RNA1509_23357, RNA1509_59583} {RNA1310_46363.1, RNA1509_23357} {RNA1509_23357, RNA815_23794}
36. MligTC455_28753 64 1.32 Mlig455_018409, Mlig455_067736, Mlig455_069521

Neo: -

Age: -

 0.964 - - - - 0.964 -

Mlig455_018409 {REF} {Length: 979} {RNA1509_27801} {RNA1310_32897} {RNA815_15953.2}

Mlig455_067736 {REF} {Length: 1136} {RNA1509_13494} {RNA1310_32897} {RNA815_15953.1}

Mlig455_069521 {REF} {Length: 982} {RNA1509_27801} {RNA1310_32897} {RNA815_15953.2}
37. MligTC455_12948 219 4.56 Mlig455_063764

Neo: Germline

Age: Up-Down-Down

Region-specific R4: 4.758

Region-enriched R4: 2.552/0.00199

 0.962 - - 0.962 - - - Mlig455_063764 {REF} {Length: 1457} {RNA1509_21657} {RNA1310_23948, RNA1509_21657} {RNA1509_21657, RNA815_10279}
38. MligTC455_15448 1109 23.1 Mlig455_051485

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=2.807

Region-enriched R3: 5.610/0.00000
Region-enriched R4: 4.154/0.00029

 MEP1B 0.962 - - - - 0.962 - Mlig455_051485 {REF} {Length: 966} {Pfam: Astacin (Peptidase family M12A) [PF01400.26, score=152.5]} {Human: ENSG00000141434, MEP1B, meprin A subunit beta, [Score=105, Expect=3e-25]; ENSG00000188886, ASTL, astacin like metalloendopeptidase, [Score=100, Expect=7e-24]} {Mouse: ENSMUSG00000024313, Mep1b, meprin 1 beta, [Score=104, Expect=4e-25]; ENSMUSG00000023914, Mep1a, meprin 1 alpha, [Score=102, Expect=2e-24]; ENSMUSG00000053626, Tll1, tolloid-like, [Score=99.4, Expect=2e-23]} {Dmel: FBgn0028949, CG15254, [Score=119, Expect=3e-32]} {Celegans: WBGene00003523, nas-4, Zinc metalloproteinase nas-4, [Score=119, Expect=4e-32]} {Smed: dd_Smed_v6_51_1_2, dd_Smed_v6_51_1_2, [RH, Score=148, Expect=7e-44]} {RNA1509_16597, RNA1509_2724} {RNA1310_37686, RNA1509_16597, RNA1509_2724} {RNA1509_16597, RNA1509_2724, RNA815_17836}
39. MligTC455_29880 6 0.13 Mlig455_032204

Neo: -

Age: -

 TMEM26 0.962 - - - - 0.962 - Mlig455_032204 {REF} {Length: 2863} {Pfam: Transmembrane protein 26 [PF09772.11, score=248.5]; Ankyrin repeats (many copies) [PF13637.8, score=46.6]; Ankyrin repeats (many copies) [PF13857.8, score=46.0]; Ankyrin repeats (3 copies) [PF12796.9, score=43.5]; Ankyrin repeat [PF13606.8, score=36.8]; Ankyrin repeat [PF00023.32, score=33.8]} {Human: ENSG00000196932, TMEM26, transmembrane protein 26, [Score=109, Expect=2e-25]} {Mouse: ENSMUSG00000060044, Tmem26, transmembrane protein 26, [Score=111, Expect=3e-26]} {Dmel: FBgn0039429, CG14238, [Score=149, Expect=2e-38]} {Celegans: WBGene00022469, Y119C1B.3, [Score=125, Expect=1e-30]} {Smed: dd_Smed_v6_30929_0_1, dd_Smed_v6_30929_0_1, [Score=119, Expect=6e-29]} {RNA1509_44391} {RNA1310_35836} {RNA815_14435}
40. MligTC455_10114 8 0.17 Mlig455_054091

Neo: -

Age: -

 0.961 - - - - 0.961 - Mlig455_054091 {REF} {Length: 1230} {NoTransDecoderORF} {RNA1310_19175} {RNA815_22011}
41. MligTC455_53725 4033 84.02 Mlig455_018435

Neo: -

Age: logFC(26M/2M)=0.835

Region-enriched R3: 3.251/0.00000
Region-enriched R4: 1.601/0.04839

 LCT 0.96 - - - - 0.960 - Mlig455_018435 {REF} {Length: 2415} {Pfam: Glycosyl hydrolase family 1 [PF00232.20, score=536.9]} {Human: ENSG00000115850, LCT, lactase, [RH, Score=441, Expect=2e-138]} {Mouse: ENSMUSG00000026354, Lct, lactase, [RH, Score=438, Expect=2e-137]} {Dmel: FBgn0036659, CG9701, [RH, Score=408, Expect=2e-137]} {Celegans: WBGene00016848, klo-1, KLOtho (Mammalian aging-associated protein) homolog, [RH, Score=333, Expect=7e-109]} {RNA1509_24508, RNA1509_405} {RNA1310_10431.1, RNA1509_24508, RNA1509_405} {RNA1509_24508, RNA1509_405, RNA815_3875.1}
42. MligTC455_21509 178 3.71 Mlig455_020862, Mlig455_020986

Neo: -

Age: Up-Up-Down

 0.955 - - 0.955 - - -

Mlig455_020862 {REF} {Length: 1411} {NoTransDecoderORF} {RNA1509_23985} {RNA1310_2424} {RNA815_39326}

Mlig455_020986 {REF} {Length: 2736} {NoTransDecoderORF} {RNA1509_23985} {RNA1310_2424} {RNA815_39326}
43. MligTC455_45462 20 0.41 Mlig455_069728

Neo: -

Age: -

 0.955 - - - - 0.955 - Mlig455_069728 {REF} {Length: 2502} {RNA1509_17147} {RNA1310_99424} {RNA815_51076}
44. MligTC455_07434 11 0.23 Mlig455_000460

Neo: -

Age: -

 0.953 - - - - - 0.953 Mlig455_000460 {REF} {Length: 396} {NoTransDecoderORF}
45. MligTC455_50325 106 2.21 Mlig455_039014

Neo: -

Age: Down-Up-Down

 0.952 - - - - 0.952 - Mlig455_039014 {REF} {Length: 3687} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=28.4]; Ankyrin repeats (many copies) [PF13637.8, score=21.9]} {RNA1509_48933, RNA1509_5355, RNA1509_59135} {RNA1310_787.1, RNA1509_48933, RNA1509_59135} {RNA1509_48933, RNA1509_59135, RNA815_223}
46. MligTC455_14480 9 0.19 Mlig455_057564

Neo: -

Age: -

 0.951 - - - - 0.951 - Mlig455_057564 {REF} {Length: 2088} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=20.0]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [Score=146, Expect=2e-37]} {RNA1310_34907} {RNA815_42361}
47. MligTC455_11005 58 1.21 Mlig455_016552

Neo: Int S/G2/M

Age: Up-Down-Down

Region-enriched R4: 4.838/0.00052

 TIMM50 0.95 - - 0.950 - - - Mlig455_016552 {REF} {Length: 1307} {Pfam: NLI interacting factor-like phosphatase [PF03031.20, score=68.9]} {Human: ENSG00000105197, TIMM50, translocase of inner mitochondrial membrane 50, [Score=49.3, Expect=4e-06]} {Mouse: ENSMUSG00000003438, Timm50, translocase of inner mitochondrial membrane 50, [Score=49.3, Expect=2e-06]} {RNA1509_50253} {RNA1310_32792, RNA1509_50253} {RNA1509_50253, RNA815_34377}
48. MligTC455_27249 48 1 Mlig455_070833

Neo: -

Age: -

 ZBTB11 0.95 - - - - 0.950 - Mlig455_070833 {REF} {Length: 6386} {Pfam: C2H2-type zinc-finger domain [PF13909.8, score=66.0]; Zinc-finger double domain [PF13465.8, score=35.9]; Zinc finger C2H2-type, 3 repeats [PF18868.3, score=28.6]; Zinc finger, C2H2 type [PF00096.28, score=21.3]} {Human: ENSG00000066422, ZBTB11, zinc finger and BTB domain containing 11, [Score=82.4, Expect=4e-15]} {Mouse: ENSMUSG00000022601, Zbtb11, zinc finger and BTB domain containing 11, [Score=79.7, Expect=2e-14]; ENSMUSG00000070495, Ctcfl, CCCTC-binding factor (zinc finger protein)-like, [Score=77.0, Expect=7e-14]} {Dmel: FBgn0031573, CG3407, [Score=79.3, Expect=1e-14]} {Celegans: WBGene00021846, ztf-23, Zinc finger putative Transcription Factor family, [Score=63.5, Expect=5e-10]} {Smed: dd_Smed_v6_5177_0_1, dd_Smed_v6_5177_0_1, [RH, Score=201, Expect=3e-52]} {RNA1509_11185} {RNA1310_1102.2} {RNA815_1398}

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