Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_42605 | 857 | 17.85 | Mlig455_028176 | Neo: - Age: - Region-enriched R6: 2.763/0.00006 Regeneration-downregulated BL: -2.101 Regeneration-depleted BL: -2.101 |
Mlig455_028176 {REF} {Length: 1295} {Pfam: Immunoreceptor tyrosine-based activation motif [PF02189.17, score=45.3]} {RNA1509_19563} {RNA1310_42765.2} {RNA815_22214} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -8.038 | 4.343 | 0.00516 | 0.22622 | |
RegionR2 | 0.48 | 4.343 | 0.60150 | 0.95162 | |
RegionR3 | -0.153 | 4.343 | 0.89395 | 1.00000 | |
RegionR4 | 0.487 | 4.343 | 0.59467 | 0.90865 | |
RegionR5 | 0.323 | 4.343 | 0.69170 | 1.00000 | |
RegionR6 | 2.763 | 4.343 | 0.00000 | 0.00006 | |
RegionR7 | 2.606 | 4.343 | 0.00001 | 0.00071 | |
RegionR8 | 1.532 | 4.343 | 0.07909 | 0.53581 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.437 | 4.343 | 1.00000 | 1.00000 | |
RegenerationR2 | 0.404 | 4.343 | 0.40940 | 0.81994 | |
RegenerationR3 | -0.936 | 4.343 | 0.11465 | 0.52855 | |
RegenerationR4 | -0.166 | 4.343 | 0.76092 | 0.97306 | |
RegenerationR5 | -0.566 | 4.343 | 0.30433 | 0.73162 | |
RegenerationR6 | -0.298 | 4.343 | 0.53604 | 0.83038 | |
RegenerationBL | -2.101 | 4.343 | 0.00029 | 0.00969 | Specific for BL: -2.101 |
RegenerationTP | -0.2 | 4.343 | 0.70875 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_42605 | 857 | 17.85 | Mlig455_028176 | Neo: - Age: - Region-enriched R6: 2.763/0.00006 Regeneration-downregulated BL: -2.101 Regeneration-depleted BL: -2.101 |
6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_028176 {REF} {Length: 1295} {Pfam: Immunoreceptor tyrosine-based activation motif [PF02189.17, score=45.3]} {RNA1509_19563} {RNA1310_42765.2} {RNA815_22214} | |
2. | MligTC455_46110 | 114 | 2.38 | Mlig455_007399, Mlig455_007500 | Neo: - Age: - |
1.838 | - | - | 0.886 | - | 0.952 | - | Mlig455_007399 {REF} {Length: 2703} {RNA1509_46950} {RNA1310_23153} {RNA815_19248} Mlig455_007500 {REF} {Length: 2693} {RNA1509_46950} {RNA1310_23153} {RNA815_19248} |
|
3. | MligTC455_33602 | 99 | 2.06 | Mlig455_025373, Mlig455_025421 | Neo: - Age: Down-Up-Down |
1.678 | 0.728 | - | - | - | - | 0.950 | Mlig455_025373 {REF} {Length: 1900} {RNA1310_26653} {RNA815_18547} Mlig455_025421 {REF} {Length: 1816} {RNA1310_26653} {RNA815_18547} |
|
4. | MligTC455_49337 | 141 | 2.94 | Mlig455_004942 | Neo: - Age: - Region-enriched R2: 4.260/0.00004 |
CA7 | 0.982 | - | - | - | - | - | 0.982 | Mlig455_004942 {REF} {Length: 2623} {Pfam: Eukaryotic-type carbonic anhydrase [PF00194.23, score=206.7]} {Human: ENSG00000168748, CA7, carbonic anhydrase 7, [Score=157, Expect=2e-45]} {Mouse: ENSMUSG00000031883, Car7, carbonic anhydrase 7, [Score=156, Expect=2e-45]} {Dmel: FBgn0027844, CAH1, Carbonic anhydrase 1, [Score=129, Expect=8e-35]} {Celegans: WBGene00000283, cah-5, Putative carbonic anhydrase 5, [Score=89.4, Expect=4e-20]} {Smed: dd_Smed_v6_11683_0_1, dd_Smed_v6_11683_0_1, [Score=160, Expect=1e-46]} {RNA1509_43765} {RNA1310_22186} {RNA815_18428} |
5. | MligTC455_25824 | 372 | 7.76 | Mlig455_010952, Mlig455_033109 | Neo: - Age: - |
AP1G1 | 0.978 | - | - | - | - | 0.978 | - | Mlig455_010952 {REF} {Length: 4898} {Pfam: Adaptin N terminal region [PF01602.22, score=450.7]; Adaptin C-terminal domain [PF02883.22, score=80.3]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=30.5]; HEAT repeats [PF13646.8, score=19.2]} {Human: ENSG00000166747, AP1G1, adaptor related protein complex 1 subunit gamma 1, [RH, Score=882, Expect=0.0]} {Mouse: ENSMUSG00000031731, Ap1g1, adaptor protein complex AP-1, gamma 1 subunit, [RH, Score=882, Expect=0.0]} {Dmel: FBgn0030089, AP-1gamma, Adaptor Protein complex 1, gamma subunit, [RH, Score=772, Expect=0.0]} {Celegans: WBGene00000158, apg-1, AdaPtin, Gamma chain (Clathrin associated complex), [RH, Score=761, Expect=0.0]} {Smed: dd_Smed_v6_2681_0_1, dd_Smed_v6_2681_0_1, [RH, Score=904, Expect=0.0]} {RNA1509_2475} {RNA1310_5519} {RNA815_631.1} Mlig455_033109 {REF} {Length: 5005} {TRANSSPLICED} {Pfam: Adaptin N terminal region [PF01602.22, score=450.9]; Adaptin C-terminal domain [PF02883.22, score=80.2]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=27.2]; HEAT repeats [PF13646.8, score=19.4]} {Human: ENSG00000166747, AP1G1, adaptor related protein complex 1 subunit gamma 1, [RH, Score=877, Expect=0.0]} {Mouse: ENSMUSG00000031731, Ap1g1, adaptor protein complex AP-1, gamma 1 subunit, [RH, Score=877, Expect=0.0]} {Dmel: FBgn0030089, AP-1gamma, Adaptor Protein complex 1, gamma subunit, [RH, Score=768, Expect=0.0]} {Celegans: WBGene00000158, apg-1, AdaPtin, Gamma chain (Clathrin associated complex), [RH, Score=756, Expect=0.0]} {Smed: dd_Smed_v6_2681_0_1, dd_Smed_v6_2681_0_1, [RH, Score=905, Expect=0.0]} {RNA1509_2475} {RNA1310_5519} {RNA815_631.1} |
6. | MligTC455_18714 | 33 | 0.69 | Mlig455_011367 | Neo: - |
0.977 | - | - | - | - | - | 0.977 | Mlig455_011367 {REF} {Length: 790} {RNA1509_44264} {RNA1310_44221.1} {RNA815_23574} | |
7. | MligTC455_11473 | 248 | 5.17 | Mlig455_009711, Mlig455_071036 | Neo: - Age: Down-Up-Down |
CHRNA3 | 0.974 | - | - | - | - | - | 0.974 | Mlig455_009711 {REF} {Length: 2402} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=241.4]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=222.9]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=391, Expect=2e-130]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=379, Expect=6e-126]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=375, Expect=2e-124]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=390, Expect=2e-130]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=375, Expect=2e-124]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [RH, Score=499, Expect=9e-173]} {Celegans: WBGene00000043, acr-3, Acetylcholine receptor subunit beta-type acr-3, [RH, Score=426, Expect=6e-145]} {Smed: dd_Smed_v6_12146_0_1, dd_Smed_v6_12146_0_1, [Score=510, Expect=1e-176]} {RNA1509_48201} {RNA1310_10118} {RNA815_29940} Mlig455_071036 {REF} {Length: 746} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=28.1]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [Score=63.5, Expect=2e-13]} {Celegans: WBGene00000042, acr-2, Acetylcholine receptor subunit beta-type acr-2, [Score=63.9, Expect=9e-14]} {Smed: dd_Smed_v6_12535_0_1, dd_Smed_v6_12535_0_1, [Score=64.3, Expect=6e-14]} {RNA1310_21182} {RNA815_29940} |
8. | MligTC455_47219 | 259 | 5.4 | Mlig455_036855 | Neo: - Age: logFC(26M/2M)=-0.291 |
PCSK4 | 0.967 | - | - | - | - | - | 0.967 | Mlig455_036855 {REF} {Length: 3656} {TRANSSPLICED} {Pfam: Subtilase family [PF00082.24, score=139.0]; Proprotein convertase P-domain [PF01483.22, score=44.8]; Peptidase S8 pro-domain [PF16470.7, score=30.4]} {Human: ENSG00000115257, PCSK4, proprotein convertase subtilisin/kexin type 4, [Score=370, Expect=1e-116]; ENSG00000175426, PCSK1, proprotein convertase subtilisin/kexin type 1, [Score=353, Expect=3e-110]} {Mouse: ENSMUSG00000020131, Pcsk4, proprotein convertase subtilisin/kexin type 4, [Score=357, Expect=3e-113]; ENSMUSG00000021587, Pcsk1, proprotein convertase subtilisin/kexin type 1, [Score=351, Expect=2e-109]; ENSMUSG00000027419, Pcsk2, proprotein convertase subtilisin/kexin type 2, [Score=341, Expect=3e-107]} {Dmel: FBgn0004509, Fur1, Furin 1, [Score=327, Expect=1e-99]} {Celegans: WBGene00002232, kpc-1, Furin-like protease kpc-1, [Score=360, Expect=7e-114]} {Smed: dd_Smed_v6_8406_0_3, dd_Smed_v6_8406_0_3, [Score=317, Expect=3e-98]} {RNA1509_13233, RNA1509_24679, RNA1509_3476, RNA1509_57220} {RNA1310_9937, RNA1509_13233, RNA1509_24679, RNA1509_57220} {RNA1509_13233, RNA1509_24679, RNA1509_57220, RNA815_2907} |
9. | MligTC455_52447 | 60 | 1.24 | Mlig455_031650 | Neo: - Age: - |
0.962 | - | - | - | - | - | 0.962 | Mlig455_031650 {REF} {Length: 2445} {RNA1310_119345} | |
10. | MligTC455_28069 | 186 | 3.87 | Mlig455_005133 | Neo: - Age: - |
0.961 | - | - | - | 0.961 | - | - | Mlig455_005133 {REF} {Length: 967} {NoTransDecoderORF} {RNA1509_38430} {RNA1310_48089} {RNA815_51074} | |
11. | MligTC455_33051 | 144 | 3.01 | Mlig455_023086 | Neo: - Age: Up-Down-Up |
0.957 | - | - | - | - | - | 0.957 | Mlig455_023086 {REF} {Length: 1003} {RNA1509_43754} {RNA1310_42744.1} {RNA815_15153} | |
12. | MligTC455_54086 | 101 | 2.11 | Mlig455_006583, Mlig455_006693, Mlig455_006744 | Neo: - Age: - |
CACNA2D1, CACNA2D2 | 0.955 | - | - | - | - | - | 0.955 | Mlig455_006583 {REF} {Length: 4206} {Pfam: VWA N-terminal [PF08399.13, score=65.5]; Cache domain [PF02743.20, score=54.1]; von Willebrand factor type A domain [PF13519.8, score=35.8]; von Willebrand factor type A domain [PF00092.30, score=33.2]; von Willebrand factor type A domain [PF13768.8, score=26.9]} {Human: ENSG00000007402, CACNA2D2, calcium voltage-gated channel auxiliary subunit alpha2delta 2, [Score=169, Expect=5e-42]; ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=168, Expect=1e-41]; ENSG00000157445, CACNA2D3, calcium voltage-gated channel auxiliary subunit alpha2delta 3, [Score=164, Expect=2e-40]} {Mouse: ENSMUSG00000010066, Cacna2d2, calcium channel, voltage-dependent, alpha 2/delta subunit 2, [Score=171, Expect=1e-42]; ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [Score=169, Expect=3e-42]; ENSMUSG00000021991, Cacna2d3, calcium channel, voltage-dependent, alpha2/delta subunit 3, [Score=166, Expect=4e-41]} {Dmel: FBgn0028863, CG4587, [Score=146, Expect=5e-35]} {Celegans: WBGene00007041, tag-180, [Score=98.6, Expect=1e-20]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [RH, Score=1425, Expect=0.0]} {RNA1509_47212} {RNA1310_2302} {RNA815_5037} Mlig455_006693 {REF} {Length: 4381} {Pfam: VWA N-terminal [PF08399.13, score=64.3]; Cache domain [PF02743.20, score=55.6]; von Willebrand factor type A domain [PF13519.8, score=35.8]; von Willebrand factor type A domain [PF00092.30, score=33.2]; von Willebrand factor type A domain [PF13768.8, score=26.9]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=169, Expect=8e-42]; ENSG00000007402, CACNA2D2, calcium voltage-gated channel auxiliary subunit alpha2delta 2, [Score=169, Expect=5e-42]; ENSG00000157445, CACNA2D3, calcium voltage-gated channel auxiliary subunit alpha2delta 3, [Score=166, Expect=8e-41]} {Mouse: ENSMUSG00000010066, Cacna2d2, calcium channel, voltage-dependent, alpha 2/delta subunit 2, [Score=171, Expect=7e-43]; ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [Score=169, Expect=5e-42]; ENSMUSG00000021991, Cacna2d3, calcium channel, voltage-dependent, alpha2/delta subunit 3, [Score=167, Expect=2e-41]} {Dmel: FBgn0028863, CG4587, [Score=146, Expect=4e-35]} {Celegans: WBGene00007041, tag-180, [Score=98.6, Expect=2e-20]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [RH, Score=1422, Expect=0.0]} {RNA1509_47212} {RNA1310_2302, RNA1509_47212} {RNA1509_47212, RNA815_5037} Mlig455_006744 {REF} {Length: 4200} {Pfam: VWA N-terminal [PF08399.13, score=65.5]; Cache domain [PF02743.20, score=54.1]; von Willebrand factor type A domain [PF13519.8, score=35.8]; von Willebrand factor type A domain [PF00092.30, score=33.2]; von Willebrand factor type A domain [PF13768.8, score=26.9]} {Human: ENSG00000007402, CACNA2D2, calcium voltage-gated channel auxiliary subunit alpha2delta 2, [Score=169, Expect=6e-42]; ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=168, Expect=1e-41]; ENSG00000157445, CACNA2D3, calcium voltage-gated channel auxiliary subunit alpha2delta 3, [Score=164, Expect=2e-40]} {Mouse: ENSMUSG00000010066, Cacna2d2, calcium channel, voltage-dependent, alpha 2/delta subunit 2, [Score=171, Expect=2e-42]; ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [Score=169, Expect=3e-42]; ENSMUSG00000021991, Cacna2d3, calcium channel, voltage-dependent, alpha2/delta subunit 3, [Score=166, Expect=4e-41]} {Dmel: FBgn0028863, CG4587, [Score=146, Expect=5e-35]} {Celegans: WBGene00007041, tag-180, [Score=98.6, Expect=1e-20]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [RH, Score=1425, Expect=0.0]} {RNA1509_47212} {RNA1310_2302} {RNA815_5037} |
13. | MligTC455_06255 | 49 | 1.01 | Mlig455_034370, Mlig455_043880 | Neo: - Age: - |
NCKIPSD | 0.952 | - | - | - | - | 0.952 | - | Mlig455_034370 {REF} {Length: 1014} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=21.6]; Plasmodium vivax Vir protein [PF05795.13, score=19.8]; Protein of unknown function (DUF2722) [PF10846.10, score=19.4]; Spt20 family [PF12090.10, score=18.4]} {Smed: dd_Smed_v6_12159_0_1, dd_Smed_v6_12159_0_1, [Score=67.8, Expect=2e-14]} {RNA1509_25720} {RNA1310_30100} {RNA815_32844} Mlig455_043880 {REF} {Length: 8735} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=22.7]} {Human: ENSG00000213672, NCKIPSD, NCK interacting protein with SH3 domain, [RH, Score=47.4, Expect=1e-05]} {Mouse: ENSMUSG00000107055, Nckipsd, NCK interacting protein with SH3 domain, [Score=50.1, Expect=7e-06]; ENSMUSG00000032598, Nckipsd, NCK interacting protein with SH3 domain, [Score=50.1, Expect=7e-06]} {RNA1509_25720} {RNA1310_9154} {RNA815_5863} |