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Results for MligTC455_43038

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_43038 44 0.92 Mlig455_015669

Neo: -

Age: -

Mlig455_015669 {REF} {Length: 1488} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=94.0, Expect=2e-22]} {RNA1310_25409} {RNA815_23260}

Cumulative graph for MligTC455_43038

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -2.165 1.421 0.99977 1.00000
RegionR2 2.556 1.421 0.08435 0.35680
RegionR3 1.974 1.421 0.08404 0.51351
RegionR4 -0.34 1.421 0.63054 0.93886
RegionR5 -1.603 1.421 0.99985 1.00000
RegionR6 -1.988 1.421 0.99987 1.00000
RegionR7 -1.991 1.421 0.99991 1.00000
RegionR8 3.557 1.421 0.06287 0.48748

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.623 1.421 1.00000 1.00000
RegenerationR2 1.352 1.421 0.21490 0.66227
RegenerationR3 1.964 1.421 0.19669 0.63200
RegenerationR4 0.639 1.421 0.66978 0.94237
RegenerationR5 -0.668 1.421 0.99992 1.00000
RegenerationR6 -0.608 1.421 0.99995 1.00000
RegenerationBL -2.284 1.421 0.99987 1.00000
RegenerationTP -2.751 1.421 0.99988 1.00000


Genes with expression patterns similar to MligTC455_43038

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_43038 44 0.92 Mlig455_015669

Neo: -

Age: -

4 - - 1.000 1.000 1.000 1.000 Mlig455_015669 {REF} {Length: 1488} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=94.0, Expect=2e-22]} {RNA1310_25409} {RNA815_23260}
2. MligTC455_41762 102 2.13 Mlig455_032244

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.902

KREMEN2 3.645 - - 0.973 0.807 0.965 0.900 Mlig455_032244 {REF} {Length: 1054} {Pfam: WSC domain [PF01822.21, score=60.0]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.0, Expect=3e-07]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=51.2, Expect=4e-07]; ENSMUSG00000020811, Wscd1, WSC domain containing 1, [Score=50.4, Expect=8e-07]; ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=48.9, Expect=3e-06]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=57.4, Expect=4e-09]} {RNA1509_59284} {RNA1310_42674} {RNA815_21749.1}
3. MligTC455_46046 18 0.37 Mlig455_042344

Neo: -

Age: -

ASL 3.608 - - 0.984 0.850 0.869 0.905 Mlig455_042344 {REF} {Length: 1218} {Pfam: Lyase [PF00206.22, score=41.7]; WSC domain [PF01822.21, score=31.1]} {Human: ENSG00000126522, ASL, argininosuccinate lyase, [Score=77.8, Expect=4e-16]} {Mouse: ENSMUSG00000025533, Asl, argininosuccinate lyase, [Score=76.3, Expect=8e-16]} {Dmel: FBgn0032076, CG9510, [Score=70.5, Expect=6e-14]} {Smed: dd_Smed_v6_3792_0_1, dd_Smed_v6_3792_0_1, [Score=86.7, Expect=9e-20]} {RNA1509_17568} {RNA1310_77268} {RNA815_37535}
4. MligTC455_43561 47 0.98 Mlig455_019076, Mlig455_064291

Neo: -

Age: -

ASIC3 3.571 - - 0.829 0.961 0.876 0.905

Mlig455_019076 {REF} {Length: 2496} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=274.8]} {Human: ENSG00000213199, ASIC3, acid sensing ion channel subunit 3, [RH, Score=122, Expect=5e-29]} {Mouse: ENSMUSG00000020704, Asic2, acid-sensing (proton-gated) ion channel 2, [Score=114, Expect=1e-26]} {Dmel: FBgn0030795, ppk28, pickpocket 28, [Score=58.5, Expect=9e-09]} {Celegans: WBGene00012137, asic-2, Degenerin-like protein asic-2, [Score=133, Expect=5e-33]} {Smed: dd_Smed_v6_17021_0_1, dd_Smed_v6_17021_0_1, [Score=127, Expect=4e-31]} {RNA1509_37765} {RNA1310_15854} {RNA815_39159}

Mlig455_064291 {REF} {Length: 2206} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=52.6]} {Celegans: WBGene00012137, asic-2, Degenerin-like protein asic-2, [Score=46.6, Expect=1e-06]} {Smed: dd_Smed_v6_26469_0_1, dd_Smed_v6_26469_0_1, [Score=47.8, Expect=1e-07]} {RNA1509_37765} {RNA1310_15854} {RNA815_28789}
5. MligTC455_13503 70 1.46 Mlig455_010582, Mlig455_010601

Neo: -

Age: -

TRHR 3.566 - - 0.916 0.907 0.775 0.968

Mlig455_010582 {REF} {Length: 2404} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=41.0]} {Human: ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=53.1, Expect=4e-07]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=57.8, Expect=1e-08]} {Dmel: FBgn0029723, Proc-R, Proctolin receptor, [Score=66.2, Expect=2e-11]} {Celegans: WBGene00016265, trhr-1, Thyrotropin-Releasing Hormone Receptor, [Score=55.1, Expect=4e-08]} {Smed: dd_Smed_v6_25364_0_1, dd_Smed_v6_25364_0_1, [Score=167, Expect=2e-47]} {RNA1310_120532}

Mlig455_010601 {REF} {Length: 2481} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=52.6]} {Human: ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=56.2, Expect=5e-08]} {Mouse: ENSMUSG00000038760, Trhr, thyrotropin releasing hormone receptor, [Score=57.0, Expect=2e-08]; ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=57.0, Expect=2e-08]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=74.3, Expect=6e-14]} {Celegans: WBGene00020069, R13H7.2, [Score=54.7, Expect=6e-08]} {Smed: dd_Smed_v6_13560_0_1, dd_Smed_v6_13560_0_1, [RH, Score=177, Expect=3e-51]} {RNA1310_92274}
6. MligTC455_50827 107 2.22 Mlig455_037867

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.688

WSCD2 3.555 - - 0.961 0.839 0.850 0.905 Mlig455_037867 {REF} {Length: 912} {Pfam: WSC domain [PF01822.21, score=58.4]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.8, Expect=1e-07]; ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=50.4, Expect=5e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=53.9, Expect=4e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.9, Expect=2e-08]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=46.2, Expect=8e-06]} {RNA1509_59284} {RNA1310_52794.1} {RNA815_21749.1}
7. MligTC455_16780 59 1.22 Mlig455_003112, Mlig455_062777

Neo: -

Age: -

3.545 - - 0.976 0.873 0.809 0.887

Mlig455_003112 {REF} {Length: 1644} {Pfam: PAN domain [PF14295.8, score=23.1]} {RNA1509_48973} {RNA1310_82250} {RNA815_43010}

Mlig455_062777 {REF} {Length: 1721} {RNA1509_48973} {RNA1310_82250} {RNA815_43010}
8. MligTC455_18539 1250 26.03 Mlig455_003030

Neo: -

Age: logFC(26M/2M)=-0.308

Region-specific R2: 5.210

Region-enriched R2: 4.715/0.00000
Region-enriched R3: 3.959/0.00000

SFRP2 3.54 - - 0.818 0.953 0.875 0.894 Mlig455_003030 {REF} {Length: 2108} {Pfam: Fz domain [PF01392.24, score=88.0]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [RH, Score=166, Expect=7e-48]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [RH, Score=165, Expect=2e-47]; ENSMUSG00000031548, Sfrp1, secreted frizzled-related protein 1, [RH, Score=157, Expect=2e-44]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=100, Expect=2e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=6e-47]} {Smed: dd_Smed_v6_8832_0_1, dd_Smed_v6_8832_0_1, [RH, Score=153, Expect=4e-43]} {RNA1509_32854, RNA1509_44148, RNA1509_5709} {RNA1310_15264, RNA1509_32854, RNA1509_44148, RNA1509_5709} {RNA1509_32854, RNA1509_44148, RNA1509_5709, RNA815_7067}
9. MligTC455_18540 1213 25.28 Mlig455_003235

Neo: -

Age: -

Region-specific R2: 5.238

Region-enriched R2: 4.787/0.00000
Region-enriched R3: 3.982/0.00000

SFRP2 3.529 - - 0.831 0.950 0.855 0.893 Mlig455_003235 {REF} {Length: 1691} {TRANSSPLICED} {Pfam: Fz domain [PF01392.24, score=86.0]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [RH, Score=167, Expect=4e-46]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [RH, Score=165, Expect=2e-45]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=101, Expect=8e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=1e-44]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [RH, Score=157, Expect=1e-42]} {RNA1509_5709} {RNA1310_15264} {RNA815_7067}
10. MligTC455_51200 66 1.37 Mlig455_057090

Neo: -

Age: -

3.525 - - 0.929 0.874 0.724 0.998 Mlig455_057090 {REF} {Length: 988} {RNA1310_63663} {RNA815_36272}
11. MligTC455_36372 925 19.28 Mlig455_005680

Neo: -

Age: logFC(26M/2M)=2.101

Region-enriched R2: 7.233/0.00006
Region-enriched R3: 5.803/0.00007

3.518 - - 0.835 0.810 0.912 0.961 Mlig455_005680 {REF} {Length: 1993} {RNA1509_18409, RNA1509_31432} {RNA1310_82233, RNA1509_18409, RNA1509_31432} {RNA1509_18409, RNA1509_31432, RNA815_42934}
12. MligTC455_43750 799 16.65 Mlig455_060601, Mlig455_060642

Neo: -

Age: logFC(26M/2M)=0.548

Region-specific R2: 5.695

Region-enriched R2: 4.415/0.00001

3.505 - - 0.854 0.762 0.918 0.971

Mlig455_060601 {REF} {Length: 722} {RNA1509_23811, RNA1509_48787} {RNA1310_60850, RNA1509_23811, RNA1509_48787} {RNA1509_23811, RNA1509_48787, RNA815_31279}

Mlig455_060642 {REF} {Length: 646} {RNA1509_23811} {RNA1310_60850} {RNA815_31279}
13. MligTC455_43224 3195 66.56 Mlig455_035023, Mlig455_053445

Neo: -

Age: logFC(26M/2M)=-1.026

Region-enriched R2: 9.114/0.00000
Region-enriched R3: 6.264/0.00000

ELSPBP1 3.497 - - 0.968 0.752 0.827 0.950

Mlig455_035023 {REF} {Length: 1139} {Pfam: Fibronectin type II domain [PF00040.21, score=74.2]; Calcium-binding EGF domain [PF07645.17, score=23.1]} {Human: ENSG00000169393, ELSPBP1, epididymal sperm binding protein 1, [RH, Score=64.7, Expect=2e-12]} {Mouse: ENSMUSG00000031740, Mmp2, matrix metallopeptidase 2, [Score=65.9, Expect=6e-12]} {Smed: dd_Smed_v6_1748_0_1, dd_Smed_v6_1748_0_1, [Score=49.7, Expect=8e-07]} {RNA1509_10278} {RNA1310_30498} {RNA815_14035}

Mlig455_053445 {REF} {Length: 1153} {Pfam: Fibronectin type II domain [PF00040.21, score=74.7]; Calcium-binding EGF domain [PF07645.17, score=25.5]} {Human: ENSG00000169393, ELSPBP1, epididymal sperm binding protein 1, [RH, Score=64.7, Expect=2e-12]} {Mouse: ENSMUSG00000031740, Mmp2, matrix metallopeptidase 2, [Score=65.9, Expect=7e-12]} {Smed: dd_Smed_v6_1748_0_1, dd_Smed_v6_1748_0_1, [Score=49.7, Expect=9e-07]} {RNA1509_10278} {RNA1310_30498, RNA1509_10278} {RNA1509_10278, RNA815_14035}
14. MligTC455_04170 65 1.36 Mlig455_000555, Mlig455_030353

Neo: -

Age: -

FGG 3.49 - - 0.970 0.798 0.846 0.876

Mlig455_000555 {REF} {Length: 1133} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=125.0]} {Human: ENSG00000171557, FGG, fibrinogen gamma chain, [Score=103, Expect=3e-24]; ENSG00000120332, TNN, tenascin N, [Score=98.2, Expect=3e-22]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=102, Expect=6e-25]; ENSMUSG00000026938, Fcna, ficolin A, [Score=99.4, Expect=1e-23]; ENSMUSG00000033860, Fgg, fibrinogen gamma chain, [Score=98.2, Expect=9e-23]; ENSMUSG00000026725, Tnn, tenascin N, [Score=98.2, Expect=2e-22]} {Dmel: FBgn0051832, CG31832, [Score=88.2, Expect=2e-20]} {Celegans: WBGene00020516, T15B7.1, [Score=62.4, Expect=8e-11]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=72.4, Expect=4e-14]} {RNA1310_33683.2} {RNA815_41841}

Mlig455_030353 {REF} {Length: 1214} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=126.3]} {Human: ENSG00000171557, FGG, fibrinogen gamma chain, [Score=103, Expect=3e-24]; ENSG00000120332, TNN, tenascin N, [Score=99.4, Expect=3e-22]; ENSG00000160339, FCN2, ficolin 2, [Score=98.2, Expect=6e-23]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=102, Expect=1e-24]; ENSMUSG00000026938, Fcna, ficolin A, [Score=100, Expect=1e-23]; ENSMUSG00000026725, Tnn, tenascin N, [Score=99.0, Expect=2e-22]; ENSMUSG00000033860, Fgg, fibrinogen gamma chain, [Score=99.0, Expect=9e-23]} {Dmel: FBgn0051832, CG31832, [Score=92.0, Expect=9e-22]} {Celegans: WBGene00020516, T15B7.1, [Score=63.2, Expect=4e-11]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=75.9, Expect=4e-15]} {RNA1310_33683.2} {RNA815_41841}
15. MligTC455_14126 1888 39.32 Mlig455_031057

Neo: Irradiation

Age: Up-Down-Down, logFC(26M/2M)=-1.763

Region-specific R2: 6.685

Region-enriched R2: 8.246/0.00000
Region-enriched R3: 3.831/0.00174

Regeneration-downregulated R2: -3.933

Regeneration-depleted R2: -3.933

SSPO 3.487 - - 0.971 0.886 0.895 0.735 Mlig455_031057 {REF} {Length: 3178} {Pfam: Spondin-like TSP1 domain [PF19028.2, score=118.7]; Thrombospondin type 1 domain [PF00090.21, score=76.9]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=46.2]; CCN3 Nov like TSP1 domain [PF19035.2, score=19.7]} {Human: ENSG00000197558, SSPO, SCO-spondin, [Score=115, Expect=2e-25]} {Mouse: ENSMUSG00000029797, Sspo, SCO-spondin, [Score=113, Expect=9e-25]} {Dmel: FBgn0026721, fat-spondin, [Score=65.5, Expect=2e-10]} {Celegans: WBGene00006893, spon-1, SPONdin (Extracellular matrix glycoprotein) family, [Score=74.3, Expect=3e-13]} {Smed: dd_Smed_v6_628_0_1, dd_Smed_v6_628_0_1, [RH, Score=487, Expect=3e-156]} {RNA1509_2451} {RNA1310_3554.1} {RNA815_1109}
16. MligTC455_48358 291 6.07 Mlig455_009342, Mlig455_036996

Neo: -

Age: -

Region-specific R2: 6.920

Region-enriched R2: 5.581/0.00062

FOXA2 3.467 - - 0.969 0.835 0.776 0.887

Mlig455_009342 {REF} {Length: 3571} {Pfam: Forkhead domain [PF00250.20, score=129.1]} {Human: ENSG00000125798, FOXA2, forkhead box A2, [RH, Score=237, Expect=2e-71]; ENSG00000129514, FOXA1, forkhead box A1, [RH, Score=231, Expect=3e-69]} {Mouse: ENSMUSG00000037025, Foxa2, forkhead box A2, [RH, Score=243, Expect=5e-74]; ENSMUSG00000035451, Foxa1, forkhead box A1, [RH, Score=231, Expect=2e-69]} {Dmel: FBgn0000659, fkh, fork head, [RH, Score=245, Expect=1e-72]} {Celegans: WBGene00004013, pha-4, Defective pharyngeal development protein 4, [RH, Score=204, Expect=6e-59]} {Smed: dd_Smed_v6_10718_0_3, dd_Smed_v6_10718_0_3, [RH, Score=246, Expect=3e-75]} {RNA1509_57651} {RNA1310_8486.1} {RNA815_24959.1}

Mlig455_036996 {REF} {Length: 3801} {Pfam: Forkhead domain [PF00250.20, score=129.0]} {Human: ENSG00000125798, FOXA2, forkhead box A2, [RH, Score=237, Expect=1e-71]; ENSG00000129514, FOXA1, forkhead box A1, [RH, Score=231, Expect=3e-69]} {Mouse: ENSMUSG00000037025, Foxa2, forkhead box A2, [RH, Score=243, Expect=5e-74]; ENSMUSG00000035451, Foxa1, forkhead box A1, [RH, Score=231, Expect=2e-69]} {Dmel: FBgn0000659, fkh, fork head, [RH, Score=245, Expect=1e-72]} {Celegans: WBGene00004013, pha-4, Defective pharyngeal development protein 4, [RH, Score=204, Expect=7e-59]} {Smed: dd_Smed_v6_10718_0_3, dd_Smed_v6_10718_0_3, [RH, Score=246, Expect=3e-75]} {RNA1509_57651} {RNA1310_8486.1, RNA1509_57651} {RNA1509_57651, RNA815_24959.1}
17. MligTC455_34693 336 7 Mlig455_017459

Neo: -

Age: -

Region-enriched R2: 6.024/0.00000
Region-enriched R3: 3.452/0.00414

FZD4 3.46 - - 0.732 0.929 0.809 0.990 Mlig455_017459 {REF} {Length: 3882} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=335.8]; Fz domain [PF01392.24, score=90.0]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=424, Expect=3e-141]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=423, Expect=3e-141]} {Dmel: FBgn0001085, fz, frizzled, [Score=306, Expect=2e-95]} {Celegans: WBGene00003006, lin-17, Transmembrane receptor LIN-17, [RH, Score=271, Expect=1e-82]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=473, Expect=3e-160]} {RNA1509_10294} {RNA1310_2672} {RNA815_3209}
18. MligTC455_22501 73 1.51 Mlig455_036417

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.645

SLC6A4 3.458 - - 0.979 0.718 0.770 0.991 Mlig455_036417 {REF} {Length: 3681} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=681.8]} {Human: ENSG00000108576, SLC6A4, solute carrier family 6 member 4, [RH, Score=610, Expect=0.0]} {Mouse: ENSMUSG00000020838, Slc6a4, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, [RH, Score=599, Expect=0.0]} {Dmel: FBgn0010414, SerT, Serotonin transporter, [RH, Score=631, Expect=0.0]} {Celegans: WBGene00003387, mod-5, Transporter, [RH, Score=559, Expect=0.0]} {Smed: dd_Smed_v6_12700_0_1, dd_Smed_v6_12700_0_1, [RH, Score=691, Expect=0.0]} {RNA1509_33614} {RNA1310_10815, RNA1509_33614} {RNA1509_33614, RNA815_8003}
19. MligTC455_50828 27 0.57 Mlig455_037962

Neo: -

Age: -

WSCD2 3.449 - - 0.975 0.751 0.818 0.905 Mlig455_037962 {REF} {Length: 911} {Pfam: WSC domain [PF01822.21, score=58.4]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.8, Expect=1e-07]; ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=50.8, Expect=5e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=53.9, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=55.5, Expect=7e-09]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=46.2, Expect=8e-06]} {RNA1509_59284} {RNA1310_52794.1} {RNA815_21749.1}
20. MligTC455_27186 28 0.57 Mlig455_010236

Neo: -

Age: logFC(26M/2M)=-1.855

3.418 - - 0.978 0.788 0.843 0.809 Mlig455_010236 {REF} {Length: 486} {RNA1509_7146} {RNA1310_76234.2} {RNA815_34947.2}
21. MligTC455_40341 106 2.2 Mlig455_060207, Mlig455_070456

Neo: -

Age: Down-Down-Up

Region-enriched R2: 6.703/0.00648
Region-enriched R3: 4.045/0.03110

NPY2R 3.417 - - 0.980 0.813 0.748 0.876

Mlig455_060207 {REF} {Length: 3062} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=177.2]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=47.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=29.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=18.6]} {Human: ENSG00000185149, NPY2R, neuropeptide Y receptor Y2, [RH, Score=178, Expect=9e-51]} {Mouse: ENSMUSG00000028004, Npy2r, neuropeptide Y receptor Y2, [RH, Score=176, Expect=3e-50]; ENSMUSG00000031932, Gpr83, G protein-coupled receptor 83, [RH, Score=176, Expect=1e-49]} {Dmel: FBgn0036934, sNPF-R, short neuropeptide F receptor, [Score=245, Expect=4e-74]} {Celegans: WBGene00009619, npr-6, NeuroPeptide Receptor family, [RH, Score=215, Expect=5e-65]} {Smed: dd_Smed_v6_15335_0_1, dd_Smed_v6_15335_0_1, [RH, Score=313, Expect=2e-103]} {RNA1310_18147.1} {RNA815_7986}

Mlig455_070456 {REF} {Length: 3569} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=176.7]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=46.8]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=29.2]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=18.3]} {Human: ENSG00000185149, NPY2R, neuropeptide Y receptor Y2, [RH, Score=177, Expect=8e-50]} {Mouse: ENSMUSG00000028004, Npy2r, neuropeptide Y receptor Y2, [RH, Score=175, Expect=3e-49]; ENSMUSG00000031932, Gpr83, G protein-coupled receptor 83, [RH, Score=174, Expect=2e-48]} {Dmel: FBgn0035610, Lkr, Leucokinin receptor, [RH, Score=166, Expect=2e-44]} {Celegans: WBGene00009619, npr-6, NeuroPeptide Receptor family, [Score=215, Expect=4e-64]} {Smed: dd_Smed_v6_15335_0_1, dd_Smed_v6_15335_0_1, [RH, Score=315, Expect=8e-103]} {RNA1310_18147.1} {RNA815_7986}
22. MligTC455_22502 209 4.36 Mlig455_003008, Mlig455_054590

Neo: -

Age: Up-Down-Down

SLC6A4 3.41 - - 0.997 0.715 0.777 0.921

Mlig455_003008 {REF} {Length: 3661} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=681.8]} {Human: ENSG00000108576, SLC6A4, solute carrier family 6 member 4, [RH, Score=610, Expect=0.0]} {Mouse: ENSMUSG00000020838, Slc6a4, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, [RH, Score=599, Expect=0.0]} {Dmel: FBgn0010414, SerT, Serotonin transporter, [RH, Score=631, Expect=0.0]} {Celegans: WBGene00003387, mod-5, Transporter, [RH, Score=559, Expect=0.0]} {Smed: dd_Smed_v6_12700_0_1, dd_Smed_v6_12700_0_1, [RH, Score=691, Expect=0.0]} {RNA1509_33614} {RNA1310_10815} {RNA815_8003}

Mlig455_054590 {REF} {Length: 3660} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=387.2]} {Human: ENSG00000108576, SLC6A4, solute carrier family 6 member 4, [Score=345, Expect=6e-114]} {Mouse: ENSMUSG00000020838, Slc6a4, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, [Score=339, Expect=9e-112]} {Dmel: FBgn0010414, SerT, Serotonin transporter, [Score=336, Expect=6e-111]} {Celegans: WBGene00003387, mod-5, Transporter, [Score=332, Expect=7e-109]} {Smed: dd_Smed_v6_12700_0_1, dd_Smed_v6_12700_0_1, [Score=357, Expect=2e-118]} {RNA1509_33614} {RNA1310_10815} {RNA815_8003}
23. MligTC455_51260 90 1.88 Mlig455_009349

Neo: -

Age: -

3.402 - - 0.974 0.776 0.749 0.903 Mlig455_009349 {REF} {Length: 1657} {Pfam: Universal stress protein family [PF00582.28, score=83.5]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=97.8, Expect=2e-24]} {RNA1310_30400} {RNA815_28361}
24. MligTC455_40011 150 3.12 Mlig455_004436, Mlig455_004448

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.676

3.364 - - 0.806 0.846 0.752 0.960

Mlig455_004436 {REF} {Length: 595} {RNA1310_81676}

Mlig455_004448 {REF} {Length: 1192} {RNA1310_81676}
25. MligTC455_19872 164 3.42 Mlig455_043990, Mlig455_050696

Neo: -

Age: -

Region-enriched R2: 4.725/0.00457

2.831 - - - 0.898 0.935 0.998

Mlig455_043990 {REF} {Length: 836} {RNA1310_51250}

Mlig455_050696 {REF} {Length: 951} {RNA1310_51250}
26. MligTC455_34692 37 0.77 Mlig455_017379

Neo: -

Age: -

2.81 - - 0.882 0.944 - 0.984 Mlig455_017379 {REF} {Length: 579} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_10294} {RNA1310_2672} {RNA815_25099}
27. MligTC455_15332 44 0.93 Mlig455_062622, Mlig455_067527

Neo: -

Age: -

Region-enriched R2: 7.516/0.00418

ASIC4 2.803 - - 0.968 0.858 - 0.977

Mlig455_062622 {REF} {Length: 2228} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=73.0]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=47.4, Expect=7e-06]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=51.6, Expect=2e-07]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=55.8, Expect=3e-09]} {Smed: dd_Smed_v6_19727_0_1, dd_Smed_v6_19727_0_1, [Score=53.1, Expect=2e-08]} {RNA1310_17847} {RNA815_27317}

Mlig455_067527 {REF} {Length: 1916} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=147.3]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=50.1, Expect=1e-05]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=50.8, Expect=3e-06]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=54.7, Expect=1e-07]} {Smed: dd_Smed_v6_19727_0_1, dd_Smed_v6_19727_0_1, [Score=53.5, Expect=2e-07]} {RNA1310_17847} {RNA815_27317}
28. MligTC455_46004 40 0.83 Mlig455_053399

Neo: -

Age: -

2.755 - - 0.957 0.827 - 0.971 Mlig455_053399 {REF} {Length: 583} {NoTransDecoderORF} {RNA1310_66147} {RNA815_35487}
29. MligTC455_14125 432 9.01 Mlig455_031050

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-1.941

Region-specific R2: 7.318

Region-enriched R2: 7.339/0.00000
Region-enriched R3: 3.316/0.02772

OTOG 2.749 - - 0.989 0.896 0.864 - Mlig455_031050 {REF} {Length: 2951} {Pfam: Spondin-like TSP1 domain [PF19028.2, score=32.8]; Pacifastin inhibitor (LCMII) [PF05375.15, score=25.4]} {Human: ENSG00000188162, OTOG, otogelin, [Score=49.3, Expect=6e-06]} {Mouse: ENSMUSG00000029797, Sspo, SCO-spondin, [Score=53.9, Expect=1e-07]} {Smed: dd_Smed_v6_628_0_1, dd_Smed_v6_628_0_1, [Score=117, Expect=3e-29]} {RNA1509_2451} {RNA1310_3554.1} {RNA815_1109}
30. MligTC455_09115 8 0.17 Mlig455_062552

Neo: -

Age: -

2.718 - - 1.000 0.813 0.905 - Mlig455_062552 {REF} {Length: 2058} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=143.1]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=57.8, Expect=1e-08]} {Smed: dd_Smed_v6_15195_0_1, dd_Smed_v6_15195_0_1, [Score=52.0, Expect=6e-07]} {RNA1310_85150} {RNA815_45687}
31. MligTC455_16471 45 0.94 Mlig455_042944

Neo: -

Age: -

NKX2-3 2.712 - - 1.000 0.845 - 0.867 Mlig455_042944 {REF} {Length: 1426} {Pfam: Homeodomain [PF00046.31, score=67.5]} {Human: ENSG00000119919, NKX2-3, NK2 homeobox 3, [RH, Score=122, Expect=1e-31]} {Mouse: ENSMUSG00000044220, Nkx2-3, NK2 homeobox 3, [RH, Score=122, Expect=2e-31]} {Dmel: FBgn0028993, scro, scarecrow, [Score=106, Expect=3e-26]} {Celegans: WBGene00000450, ceh-28, C. Elegans Homeobox; NK-2 family homeodomain protein CEH-28, [RH, Score=97.8, Expect=4e-24]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [Score=109, Expect=3e-27]} {RNA1310_91075}
32. MligTC455_36826 28 0.58 Mlig455_013198

Neo: -

Age: -

Region-enriched R2: 5.359/0.01396

HSPB6 2.71 - - 1.000 0.853 - 0.857 Mlig455_013198 {REF} {Length: 2372} {Pfam: Hsp20/alpha crystallin family [PF00011.23, score=56.3]} {Human: ENSG00000004776, HSPB6, heat shock protein family B (small) member 6, [RH, Score=55.5, Expect=8e-09]} {Mouse: ENSMUSG00000036854, Hspb6, heat shock protein, alpha-crystallin-related, B6, [RH, Score=58.5, Expect=7e-10]} {Dmel: FBgn0011296, l(2)efl, lethal (2) essential for life, [Score=57.8, Expect=1e-09]} {Smed: dd_Smed_v6_15128_0_1, dd_Smed_v6_15128_0_1, [RH, Score=81.3, Expect=3e-17]} {RNA1310_41920} {RNA815_42079}
33. MligTC455_29224 3570 74.37 Mlig455_049141

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.673

Region-enriched R2: 5.907/0.00019
Region-enriched R3: 5.624/0.00000

2.705 - - - 0.941 0.811 0.953 Mlig455_049141 {REF} {Length: 672} {RNA1509_16346} {RNA1310_46172} {RNA815_23439}
34. MligTC455_11713 8 0.16 Mlig455_030060

Neo: -

Age: -

2.704 - - 1.000 0.869 0.835 - Mlig455_030060 {REF} {Length: 1189} {RNA1310_40798} {RNA815_26160}
35. MligTC455_13259 11 0.23 Mlig455_026238, Mlig455_042504

Neo: -

Age: -

KREMEN1 2.7 - - 0.968 0.827 - 0.905

Mlig455_026238 {REF} {Length: 468}

Mlig455_042504 {REF} {Length: 806} {Pfam: WSC domain [PF01822.21, score=46.2]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=51.6, Expect=3e-07]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=49.3, Expect=9e-07]} {RNA1310_57841} {RNA815_19006.2}
36. MligTC455_14752 17 0.36 Mlig455_009102

Neo: -

Age: -

2.694 - - 0.960 0.830 0.904 - Mlig455_009102 {REF} {Length: 1690} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=50.9]; Capsular polysaccharide synthesis protein [PF05704.14, score=18.3]} {Smed: dd_Smed_v6_9783_0_1, dd_Smed_v6_9783_0_1, [Score=89.7, Expect=1e-19]} {RNA1509_4484} {RNA1310_25467} {RNA815_39314}
37. MligTC455_29223 4140 86.24 Mlig455_049112

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.584

Region-enriched R3: 5.676/0.00000
Region-enriched R2: 5.572/0.00000

2.689 - - - 0.964 0.833 0.892 Mlig455_049112 {REF} {Length: 1072} {RNA1509_1747} {RNA1310_46172} {RNA815_23439}
38. MligTC455_09126 12 0.25 Mlig455_051248

Neo: -

Age: Up-Down-Down

TBX2 2.683 - - 1.000 0.800 - 0.883 Mlig455_051248 {REF} {Length: 2894} {Pfam: T-box [PF00907.24, score=269.9]} {Human: ENSG00000121068, TBX2, T-box 2, [RH, Score=364, Expect=3e-116]; ENSG00000135111, TBX3, T-box 3, [RH, Score=356, Expect=6e-113]} {Mouse: ENSMUSG00000018604, Tbx3, T-box 3, [RH, Score=365, Expect=1e-116]; ENSMUSG00000000093, Tbx2, T-box 2, [RH, Score=363, Expect=9e-116]} {Dmel: FBgn0000179, bi, bifid, [RH, Score=357, Expect=5e-111]} {Celegans: WBGene00006543, tbx-2, T-box protein 2, [RH, Score=318, Expect=3e-102]} {Smed: dd_Smed_v6_11693_0_1, dd_Smed_v6_11693_0_1, [RH, Score=395, Expect=2e-129]} {RNA1509_33164} {RNA1310_57171} {RNA815_39333}
39. MligTC455_12037 183 3.81 Mlig455_016647, Mlig455_016711

Neo: -

Age: Down-Up-Up

DYNLL1 2.677 - - 0.991 0.862 - 0.824

Mlig455_016647 {REF} {Length: 879} {Pfam: Dynein light chain type 1 [PF01221.20, score=69.4]} {Human: ENSG00000088986, DYNLL1, dynein light chain LC8-type 1, [Score=62.8, Expect=7e-14]; ENSG00000264364, DYNLL2, dynein light chain LC8-type 2, [Score=60.1, Expect=7e-13]} {Mouse: ENSMUSG00000009013, Dynll1, dynein light chain LC8-type 1, [Score=62.8, Expect=4e-14]; ENSMUSG00000020483, Dynll2, dynein light chain LC8-type 2, [Score=60.1, Expect=5e-13]} {Dmel: FBgn0011760, ctp, cut up, [Score=60.5, Expect=2e-13]} {Celegans: WBGene00001005, dlc-1, Dynein light chain 1, cytoplasmic, [Score=59.3, Expect=6e-13]} {Smed: dd_Smed_v6_10084_0_2, dd_Smed_v6_10084_0_2, [Score=65.9, Expect=1e-15]} {RNA1509_36890} {RNA1310_30005} {RNA815_41098}

Mlig455_016711 {REF} {Length: 890} {Pfam: Dynein light chain type 1 [PF01221.20, score=69.4]} {Human: ENSG00000088986, DYNLL1, dynein light chain LC8-type 1, [Score=62.8, Expect=5e-14]; ENSG00000264364, DYNLL2, dynein light chain LC8-type 2, [Score=60.1, Expect=7e-13]} {Mouse: ENSMUSG00000009013, Dynll1, dynein light chain LC8-type 1, [Score=62.8, Expect=4e-14]; ENSMUSG00000020483, Dynll2, dynein light chain LC8-type 2, [Score=60.1, Expect=5e-13]} {Dmel: FBgn0011760, ctp, cut up, [Score=60.8, Expect=2e-13]} {Celegans: WBGene00001005, dlc-1, Dynein light chain 1, cytoplasmic, [Score=59.3, Expect=5e-13]} {Smed: dd_Smed_v6_10084_0_5, dd_Smed_v6_10084_0_5, [Score=65.9, Expect=1e-15]} {RNA1509_36890} {RNA1310_30005} {RNA815_41098}
40. MligTC455_45314 24 0.5 Mlig455_043345

Neo: -

Age: -

2.656 - - 1.000 0.749 - 0.907 Mlig455_043345 {REF} {Length: 1422} {Pfam: Pancreatic hormone peptide [PF00159.20, score=27.9]} {RNA1310_91502} {RNA815_61453}
41. MligTC455_01243 37 0.77 Mlig455_055650

Neo: -

Age: -

2.647 - - 0.994 0.751 - 0.902 Mlig455_055650 {REF} {Length: 625} {Pfam: Universal stress protein family [PF00582.28, score=20.0]} {RNA1310_33871} {RNA815_28361}
42. MligTC455_36373 2360 49.17 Mlig455_008690

Neo: -

Age: -

Region-enriched R2: 7.147/0.00000
Region-enriched R3: 5.693/0.00001

2.628 - - - 0.739 0.903 0.986 Mlig455_008690 {REF} {Length: 1552} {RNA1509_2189} {RNA1310_71597} {RNA815_31926.1}
43. MligTC455_36565 119 2.47 Mlig455_049229

Neo: -

Age: -

2.624 - - - 0.794 0.861 0.969 Mlig455_049229 {REF} {Length: 2217} {Pfam: Lectin C-type domain [PF00059.23, score=25.9]} {RNA1509_20526} {RNA1310_3134} {RNA815_16425}
44. MligTC455_06678 10 0.22 Mlig455_051040

Neo: -

Age: -

SLC7A1 2.619 - - 0.745 0.963 0.911 - Mlig455_051040 {REF} {Length: 1969} {Pfam: Amino acid permease [PF13520.8, score=122.2]; Amino acid permease [PF00324.23, score=107.8]; C-terminus of AA_permease [PF13906.8, score=56.1]} {Human: ENSG00000139514, SLC7A1, solute carrier family 7 member 1, [Score=297, Expect=3e-92]} {Mouse: ENSMUSG00000041313, Slc7a1, solute carrier family 7 (cationic amino acid transporter, y+ system), member 1, [Score=300, Expect=2e-93]; ENSMUSG00000022756, Slc7a4, solute carrier family 7 (cationic amino acid transporter, y+ system), member 4, [Score=297, Expect=3e-92]; ENSMUSG00000054753, AU018091, expressed sequence AU018091, [Score=290, Expect=5e-89]; ENSMUSG00000107871, AU018091, expressed sequence AU018091, [Score=290, Expect=5e-89]} {Dmel: FBgn0036984, CG13248, [Score=290, Expect=1e-89]} {Celegans: WBGene00016806, C50D2.2, [Score=293, Expect=1e-91]} {Smed: dd_Smed_v6_8652_0_4, dd_Smed_v6_8652_0_4, [Score=436, Expect=3e-147]} {RNA1310_82370} {RNA815_51664}
45. MligTC455_40648 60 1.24 Mlig455_034479

Neo: -

Age: Down-Up-Up

2.616 - - 0.747 0.906 - 0.963 Mlig455_034479 {REF} {Length: 2499} {RNA1310_42980.1} {RNA815_47590}
46. MligTC455_42841 550 11.45 Mlig455_019999

Neo: -

Age: logFC(26M/2M)=-0.374

Region-specific R2: 6.903

Region-enriched R2: 6.896/0.00000

DDC 2.615 - - 0.966 0.882 - 0.767 Mlig455_019999 {REF} {Length: 3000} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=395.1]} {Human: ENSG00000132437, DDC, dopa decarboxylase, [Score=444, Expect=3e-151]} {Mouse: ENSMUSG00000020182, Ddc, dopa decarboxylase, [Score=436, Expect=5e-148]} {Dmel: FBgn0050446, Tdc2, Tyrosine decarboxylase 2, [Score=457, Expect=2e-154]} {Celegans: WBGene00006562, tdc-1, Tyrosine decarboxylase, [Score=445, Expect=1e-149]} {Smed: dd_Smed_v6_11320_0_1, dd_Smed_v6_11320_0_1, [Score=449, Expect=3e-153]} {RNA1509_57403} {RNA1310_9852} {RNA815_3388.1}
47. MligTC455_45556 34 0.7 Mlig455_054696

Neo: -

Age: -

TNN 2.613 - - 1.000 0.837 0.776 - Mlig455_054696 {REF} {Length: 1070} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=59.7]; PAN domain [PF00024.28, score=25.5]} {Human: ENSG00000120332, TNN, tenascin N, [Score=65.5, Expect=2e-11]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=62.8, Expect=1e-10]} {Mouse: ENSMUSG00000026725, Tnn, tenascin N, [Score=63.9, Expect=4e-11]} {Dmel: FBgn0034160, CG5550, [Score=53.1, Expect=4e-08]} {RNA1310_49192} {RNA815_37160}
48. MligTC455_43686 326 6.79 Mlig455_022166, Mlig455_055777

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.570

Region-enriched R3: 6.671/0.00000
Region-enriched R2: 5.224/0.01307

2.612 - - - 0.745 0.967 0.900

Mlig455_022166 {REF} {Length: 612} {RNA1310_23536} {RNA815_45816}

Mlig455_055777 {REF} {Length: 584} {RNA1310_23536} {RNA815_45816}
49. MligTC455_20225 18 0.38 Mlig455_042403

Neo: -

Age: -

2.605 - - 0.993 0.777 0.835 - Mlig455_042403 {REF} {Length: 1402} {Pfam: WSC domain [PF01822.21, score=50.0]; PAN domain [PF00024.28, score=21.0]} {RNA1310_77268} {RNA815_27180}
50. MligTC455_10396 50 1.05 Mlig455_046206

Neo: -

Age: -

Region-enriched R3: 5.170/0.02090

2.604 - - - 0.794 0.851 0.959 Mlig455_046206 {REF} {Length: 650} {RNA1310_75011.2} {RNA815_47673}
51. MligTC455_38775 266 5.54 Mlig455_066758, Mlig455_069705

Neo: -

Age: -

Region-specific R2: 6.147

Region-enriched R2: 5.505/0.02411

WNT6 2.602 - - 0.953 0.909 - 0.740

Mlig455_066758 {REF} {Length: 2739} {Pfam: wnt family [PF00110.21, score=158.2]} {Human: ENSG00000115596, WNT6, Wnt family member 6, [Score=77.4, Expect=9e-15]; ENSG00000134245, WNT2B, Wnt family member 2B, [Score=74.3, Expect=1e-13]} {Mouse: ENSMUSG00000033227, Wnt6, wingless-type MMTV integration site family, member 6, [Score=74.3, Expect=6e-14]; ENSMUSG00000027840, Wnt2b, wingless-type MMTV integration site family, member 2B, [Score=74.3, Expect=9e-14]} {Dmel: FBgn0031902, Wnt6, Wnt oncogene analog 6, [Score=70.9, Expect=9e-13]} {Celegans: WBGene00000857, cwn-1, [Score=73.9, Expect=4e-14]} {Smed: dd_Smed_v6_13487_0_1, dd_Smed_v6_13487_0_1, [Score=71.2, Expect=3e-13]} {RNA1509_23528} {RNA1310_12823.2} {RNA815_8552}

Mlig455_069705 {REF} {Length: 2713} {Pfam: wnt family [PF00110.21, score=158.2]} {Human: ENSG00000115596, WNT6, Wnt family member 6, [Score=77.4, Expect=1e-14]; ENSG00000134245, WNT2B, Wnt family member 2B, [Score=74.3, Expect=1e-13]} {Mouse: ENSMUSG00000033227, Wnt6, wingless-type MMTV integration site family, member 6, [Score=74.3, Expect=7e-14]; ENSMUSG00000027840, Wnt2b, wingless-type MMTV integration site family, member 2B, [Score=73.9, Expect=1e-13]} {Dmel: FBgn0031902, Wnt6, Wnt oncogene analog 6, [Score=70.9, Expect=9e-13]} {Celegans: WBGene00000857, cwn-1, [Score=73.6, Expect=6e-14]} {Smed: dd_Smed_v6_13487_0_1, dd_Smed_v6_13487_0_1, [Score=70.9, Expect=3e-13]} {RNA1509_23528} {RNA1310_12823.1, RNA1509_23528} {RNA1509_23528, RNA815_8552}
52. MligTC455_31463 20 0.42 Mlig455_057169

Neo: -

Age: -

2.597 - - 1.000 0.819 0.778 - Mlig455_057169 {REF} {Length: 1647} {Pfam: Methyltransferase FkbM domain [PF05050.14, score=39.0]} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=82.4, Expect=3e-18]} {RNA1509_6604} {RNA1310_43619} {RNA815_6128.2}
53. MligTC455_52194 4 0.07 Mlig455_042343

Neo: -

Age: -

2.589 - - 1.000 0.718 - 0.871 Mlig455_042343 {REF} {Length: 1597} {Pfam: PAN domain [PF00024.28, score=19.6]} {RNA1310_77268} {RNA815_27180}
54. MligTC455_31462 23 0.48 Mlig455_000844

Neo: -

Age: -

2.588 - - 1.000 0.809 0.779 - Mlig455_000844 {REF} {Length: 2564} {Pfam: Methyltransferase FkbM domain [PF05050.14, score=39.1]} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=81.6, Expect=5e-18]} {RNA1509_6604} {RNA1310_43619} {RNA815_6128.2}
55. MligTC455_24244 290 6.04 Mlig455_062623, Mlig455_067528, Mlig455_070336

Neo: -

Age: Down-Up-Down

Region-enriched R2: 6.603/0.00020

2.578 - - 0.997 0.873 - 0.708

Mlig455_062623 {REF} {Length: 1154} {Pfam: Putative Interleukin 2 receptor, gamma chain [PF15874.7, score=68.1]} {Smed: dd_Smed_v6_15167_0_1, dd_Smed_v6_15167_0_1, [RH, Score=71.6, Expect=3e-16]} {RNA1310_40891} {RNA815_16565}

Mlig455_067528 {REF} {Length: 1190} {Pfam: Putative Interleukin 2 receptor, gamma chain [PF15874.7, score=67.0]} {Smed: dd_Smed_v6_15167_0_1, dd_Smed_v6_15167_0_1, [RH, Score=72.4, Expect=1e-16]} {RNA1310_40891} {RNA815_16565}

Mlig455_070336 {REF} {Length: 859} {Pfam: Putative Interleukin 2 receptor, gamma chain [PF15874.7, score=67.7]} {Smed: dd_Smed_v6_15167_0_1, dd_Smed_v6_15167_0_1, [Score=57.4, Expect=1e-10]} {RNA1310_40891} {RNA815_16565}
56. MligTC455_11862 13 0.26 Mlig455_024721

Neo: -

Age: -

DLG4 2.57 - - 1.000 - 0.764 0.806 Mlig455_024721 {REF} {Length: 1968} {Pfam: PDZ domain [PF00595.26, score=63.1]; PDZ domain [PF17820.3, score=49.6]; PDZ domain [PF13180.8, score=31.6]} {Human: ENSG00000132535, DLG4, discs large MAGUK scaffold protein 4, [Score=71.6, Expect=6e-14]; ENSG00000132849, PATJ, PATJ, crumbs cell polarity complex component, [Score=68.9, Expect=3e-12]} {Mouse: ENSMUSG00000016520, Lnx2, ligand of numb-protein X 2, [Score=71.6, Expect=2e-13]; ENSMUSG00000020886, Dlg4, discs large MAGUK scaffold protein 4, [Score=70.9, Expect=7e-14]} {Dmel: FBgn0263289, scrib, scribbled, [Score=69.7, Expect=7e-13]} {Celegans: WBGene00001006, dlg-1, Drosophila Discs LarGe homolog; MAGUK protein DLG-1; SAP97-like protein DLG-1, [Score=55.8, Expect=2e-08]} {Smed: dd_Smed_v6_8994_0_1, dd_Smed_v6_8994_0_1, [Score=104, Expect=7e-25]} {RNA1509_45931} {RNA1310_25435.2} {RNA815_1460.1}
57. MligTC455_16199 114 2.37 Mlig455_041013, Mlig455_041178

Neo: Irradiation

Age: -

Region-enriched R2: 9.007/0.00037

2.57 - - 0.999 0.814 0.757 -

Mlig455_041013 {REF} {Length: 3381} {RNA1509_42904} {RNA1310_20434} {RNA815_22064}

Mlig455_041178 {REF} {Length: 2722} {RNA1509_42904} {RNA1310_20004} {RNA815_22064}
58. MligTC455_19938 250 5.2 Mlig455_063706

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.458

Region-enriched R3: 3.513/0.03723

NKX2-2 2.557 - - 0.737 0.958 - 0.862 Mlig455_063706 {REF} {Length: 2739} {Pfam: Homeodomain [PF00046.31, score=72.6]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [Score=119, Expect=3e-31]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [Score=119, Expect=1e-31]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [Score=112, Expect=2e-27]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=95.9, Expect=8e-23]} {Smed: dd_Smed_v6_2716_0_4, dd_Smed_v6_2716_0_4, [Score=118, Expect=4e-30]} {RNA1509_27298} {RNA1310_16689.1, RNA1509_27298} {RNA1509_27298, RNA815_30453}
59. MligTC455_33538 789 16.45 Mlig455_051129, Mlig455_051205

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.262

Region-specific R2: 4.638

Region-enriched R2: 3.952/0.00052

LRRIQ4 2.545 - - 0.973 0.796 0.776 -

Mlig455_051129 {REF} {Length: 1662} {Pfam: Leucine rich repeat [PF13855.8, score=77.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=61.4]} {Human: ENSG00000188306, LRRIQ4, leucine rich repeats and IQ motif containing 4, [Score=95.5, Expect=6e-21]; ENSG00000240720, LRRD1, leucine rich repeats and death domain containing 1, [Score=93.6, Expect=4e-20]; ENSG00000130224, LRCH2, leucine rich repeats and calponin homology domain containing 2, [Score=93.2, Expect=4e-20]; ENSG00000163827, LRRC2, leucine rich repeat containing 2, [Score=92.4, Expect=2e-20]; ENSG00000033122, LRRC7, leucine rich repeat containing 7, [Score=91.7, Expect=2e-19]} {Mouse: ENSMUSG00000070056, Mfhas1, malignant fibrous histiocytoma amplified sequence 1, [Score=115, Expect=9e-28]} {Dmel: FBgn0033984, Lap1, [Score=86.3, Expect=4e-18]} {Celegans: WBGene00002632, let-413, [Score=90.5, Expect=1e-19]} {Smed: dd_Smed_v6_17742_0_1, dd_Smed_v6_17742_0_1, [RH, Score=360, Expect=1e-124]} {RNA1509_30762} {RNA1310_31301} {RNA815_15435}

Mlig455_051205 {REF} {Length: 2514} {Pfam: Leucine rich repeat [PF13855.8, score=72.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=59.1]} {Human: ENSG00000188306, LRRIQ4, leucine rich repeats and IQ motif containing 4, [Score=94.7, Expect=1e-20]; ENSG00000130224, LRCH2, leucine rich repeats and calponin homology domain containing 2, [Score=93.2, Expect=4e-20]; ENSG00000240720, LRRD1, leucine rich repeats and death domain containing 1, [Score=92.8, Expect=6e-20]; ENSG00000163827, LRRC2, leucine rich repeat containing 2, [Score=92.4, Expect=2e-20]; ENSG00000033122, LRRC7, leucine rich repeat containing 7, [Score=91.3, Expect=3e-19]} {Mouse: ENSMUSG00000070056, Mfhas1, malignant fibrous histiocytoma amplified sequence 1, [Score=115, Expect=1e-27]} {Dmel: FBgn0033984, Lap1, [Score=85.5, Expect=9e-18]} {Celegans: WBGene00002632, let-413, [Score=90.5, Expect=1e-19]} {Smed: dd_Smed_v6_17742_0_1, dd_Smed_v6_17742_0_1, [RH, Score=362, Expect=2e-125]} {RNA1509_30762} {RNA1310_31301, RNA1509_30762} {RNA1509_30762, RNA815_15435}
60. MligTC455_35446 75 1.56 Mlig455_031433

Neo: -

Age: Down-Up-Up

2.531 - - 0.963 0.708 0.860 - Mlig455_031433 {REF} {Length: 1430} {NoTransDecoderORF} {RNA1310_35373} {RNA815_22739}
61. MligTC455_49676 6477 134.94 Mlig455_061478

Neo: -

Age: -

Region-enriched R2: 5.226/0.00000
Region-enriched R3: 5.025/0.00000

ZAN 2.5 - - - 0.761 0.755 0.984 Mlig455_061478 {REF} {Length: 1308} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=81.3, Expect=5e-16]} {Mouse: ENSMUSG00000049008, BB014433, expressed sequence BB014433, [Score=61.2, Expect=5e-10]} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=77.4, Expect=2e-15]} {RNA1509_4179} {RNA1310_50528} {RNA815_21638.1}
62. MligTC455_37991 22 0.46 Mlig455_018140

Neo: -

Age: -

2.495 - - 0.955 0.705 0.835 - Mlig455_018140 {REF} {Length: 2598} {Pfam: EF-hand domain pair [PF13499.8, score=36.8]; EF-hand domain [PF13405.8, score=31.2]; EF hand [PF00036.34, score=29.3]; EF-hand domain pair [PF13833.8, score=20.5]; EF hand [PF13202.8, score=19.4]} {Smed: dd_Smed_v6_1010_0_1, dd_Smed_v6_1010_0_1, [Score=104, Expect=1e-26]} {RNA1310_31713.2} {RNA815_36423}
63. MligTC455_11788 20 0.41 Mlig455_043729, Mlig455_043819, Mlig455_047429

Neo: -

Age: -

ANGPTL1 2.494 - - - 0.718 0.812 0.964

Mlig455_043729 {REF} {Length: 1137} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=144.4]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=131, Expect=2e-34]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=129, Expect=9e-34]; ENSG00000130812, ANGPTL6, angiopoietin like 6, [Score=127, Expect=5e-33]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=134, Expect=9e-36]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=131, Expect=8e-35]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=129, Expect=8e-34]} {Dmel: FBgn0003326, sca, scabrous, [Score=119, Expect=4e-30]} {Celegans: WBGene00017013, ensh-1, [Score=46.6, Expect=1e-05]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=110, Expect=4e-27]} {RNA1509_26827} {RNA1310_41424} {RNA815_48855}

Mlig455_043819 {REF} {Length: 1111} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=143.1]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=129, Expect=1e-33]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=127, Expect=4e-33]; ENSG00000130812, ANGPTL6, angiopoietin like 6, [Score=125, Expect=2e-32]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=132, Expect=5e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=130, Expect=3e-34]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=127, Expect=4e-33]} {Dmel: FBgn0003326, sca, scabrous, [Score=117, Expect=2e-29]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=108, Expect=2e-26]} {RNA1509_26827} {RNA1310_41424} {RNA815_48855}

Mlig455_047429 {REF} {Length: 1072} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=143.1]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=129, Expect=1e-33]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=127, Expect=4e-33]; ENSG00000130812, ANGPTL6, angiopoietin like 6, [Score=125, Expect=2e-32]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=132, Expect=5e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=130, Expect=3e-34]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=127, Expect=4e-33]} {Dmel: FBgn0003326, sca, scabrous, [Score=117, Expect=2e-29]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=108, Expect=2e-26]} {RNA1509_26827} {RNA1310_41424} {RNA815_48855}
64. MligTC455_25412 199 4.15 Mlig455_008720, Mlig455_063581

Neo: -

Age: -

Region-enriched R2: 7.484/0.00035

CNBD2 2.487 - - 0.991 0.782 - 0.714

Mlig455_008720 {REF} {Length: 2602} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=82.1]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [Score=52.4, Expect=3e-06]} {Smed: dd_Smed_v6_13623_0_1, dd_Smed_v6_13623_0_1, [Score=241, Expect=1e-69]} {RNA1509_50931} {RNA1310_3304} {RNA815_12767}

Mlig455_063581 {REF} {Length: 2668} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=82.3]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [Score=52.4, Expect=3e-06]} {Smed: dd_Smed_v6_13623_0_1, dd_Smed_v6_13623_0_1, [Score=241, Expect=7e-70]} {RNA1509_50931} {RNA1310_3304} {RNA815_12767}
65. MligTC455_43192 420 8.75 Mlig455_010853, Mlig455_010884

Neo: -

Age: -

Region-enriched R3: 5.568/0.01380

2.486 - - - 0.783 0.747 0.956

Mlig455_010853 {REF} {Length: 897} {RNA1310_121983}

Mlig455_010884 {REF} {Length: 898} {RNA1310_121983}
66. MligTC455_12452 172 3.59 Mlig455_043512

Neo: -

Age: -

Region-enriched R2: 6.359/0.00008

2.458 - - 0.983 0.715 0.760 - Mlig455_043512 {REF} {Length: 678} {RNA1310_67692} {RNA815_34969}
67. MligTC455_53759 2456 51.16 Mlig455_016120

Neo: -

Age: logFC(26M/2M)=-1.068

Region-enriched R2: 6.391/0.00020
Region-enriched R3: 3.793/0.01131

2.378 - - 0.959 0.719 0.700 - Mlig455_016120 {REF} {Length: 573} {RNA1509_10966, RNA1509_2075, RNA1509_23631, RNA1509_5413, RNA1509_5649} {RNA1310_97571, RNA1509_2075, RNA1509_23631, RNA1509_5413, RNA1509_5649} {RNA1509_2075, RNA1509_23631, RNA1509_5413, RNA1509_5649, RNA815_8445.4}
68. MligTC455_44662 76 1.57 Mlig455_038241

Neo: -

Age: logFC(26M/2M)=-0.868

ANO7 1.891 - - 0.917 - 0.974 - Mlig455_038241 {REF} {Length: 3705} {Pfam: Calcium-activated chloride channel [PF04547.14, score=457.8]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=572, Expect=0.0]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=561, Expect=0.0]} {Dmel: FBgn0038721, subdued, [Score=420, Expect=3e-137]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=165, Expect=1e-43]} {Smed: dd_Smed_v6_19189_0_1, dd_Smed_v6_19189_0_1, [Score=659, Expect=0.0]} {RNA1509_46639} {RNA1310_1412.2} {RNA815_15650}
69. MligTC455_19304 36 0.76 Mlig455_036451

Neo: -

Age: -

1.89 - - - 0.919 - 0.971 Mlig455_036451 {REF} {Length: 1603} {Smed: dd_Smed_v6_16261_0_1, dd_Smed_v6_16261_0_1, [RH, Score=266, Expect=8e-87]} {RNA1310_117429}
70. MligTC455_09748 23 0.48 Mlig455_021244

Neo: -

Age: -

1.889 - - 0.971 0.918 - - Mlig455_021244 {REF} {Length: 1248} {RNA1310_73799} {RNA815_52728}
71. MligTC455_24951 220 4.58 Mlig455_052169

Neo: -

Age: -

Region-specific R2: 4.554

Region-enriched R2: 4.264/0.00008

Regeneration-downregulated R2: -1.743

Regeneration-depleted R2: -1.743

CCDC169 1.877 - - 0.970 0.907 - - Mlig455_052169 {REF} {Length: 1369} {Pfam: Domain of unknown function (DUF4600) [PF15372.8, score=97.2]} {Human: ENSG00000242715, CCDC169, coiled-coil domain containing 169, [RH, Score=82.8, Expect=6e-19]} {Mouse: ENSMUSG00000048655, Ccdc169, coiled-coil domain containing 169, [RH, Score=94.0, Expect=3e-23]} {Smed: dd_Smed_v6_12011_0_1, dd_Smed_v6_12011_0_1, [RH, Score=207, Expect=9e-68]} {RNA1509_8270} {RNA1310_23029} {RNA815_11545}
72. MligTC455_41448 192 4.01 Mlig455_066626

Neo: -

Age: -

Region-specific R2: 6.449

Region-enriched R2: 4.988/0.02499

1.864 - - 0.988 0.876 - - Mlig455_066626 {REF} {Length: 987} {Pfam: F5/8 type C domain [PF00754.27, score=25.0]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [Score=52.4, Expect=8e-09]} {RNA1509_36923} {RNA1310_37535} {RNA815_20943}
73. MligTC455_27332 6690 139.38 Mlig455_034839, Mlig455_034841, Mlig455_034842

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.609

Region-specific R2: 8.988

Region-enriched R2: 9.169/0.00000

Regeneration-depleted R2: -8.701
Regeneration-depleted R3: -5.339

1.862 - - 0.991 0.871 - -

Mlig455_034839 {REF} {Length: 551} {RNA1509_2874} {RNA1310_102625.1} {RNA815_20834}

Mlig455_034841 {REF} {Length: 529} {RNA1509_2874} {RNA1310_102625.1, RNA1509_2874} {RNA1509_2874, RNA815_20834}

Mlig455_034842 {REF} {Length: 557} {RNA1509_2874} {RNA1310_102625.1} {RNA815_20834}
74. MligTC455_16487 12 0.24 Mlig455_004173

Neo: -

Age: -

1.855 - - 0.858 - - 0.997 Mlig455_004173 {REF} {Length: 716} {NoTransDecoderORF} {RNA1310_87874}
75. MligTC455_50734 175 3.66 Mlig455_044294

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.054/0.00263
Region-enriched R3: 3.364/0.00377

CHRNA3 1.855 - - - 0.970 - 0.885 Mlig455_044294 {REF} {Length: 1830} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=242.4]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=225.5]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=373, Expect=1e-123]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=365, Expect=1e-120]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=360, Expect=9e-119]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=358, Expect=6e-118]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=376, Expect=3e-125]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=374, Expect=4e-124]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=450, Expect=4e-154]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=381, Expect=2e-127]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [RH, Score=651, Expect=0.0]} {RNA1509_45903} {RNA1310_14580} {RNA815_10044.1}
76. MligTC455_31079 1616 33.66 Mlig455_009819

Neo: -

Age: logFC(26M/2M)=-1.498

Region-enriched R2: 6.662/0.00000

1.852 - - 0.953 - - 0.899 Mlig455_009819 {REF} {Length: 622} {RNA1509_31702} {RNA1310_37423.2} {RNA815_20834}
77. MligTC455_26092 67 1.39 Mlig455_048489

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.677

Region-enriched R2: 4.303/0.01110

1.851 - - 0.963 0.888 - - Mlig455_048489 {REF} {Length: 2319} {Pfam: Lectin C-type domain [PF00059.23, score=23.3]} {RNA1509_25383} {RNA1310_27113} {RNA815_24719}
78. MligTC455_48127 47 0.97 Mlig455_037173

Neo: -

Age: -

1.85 - - 0.995 0.855 - - Mlig455_037173 {REF} {Length: 1938} {RNA1310_42908} {RNA815_22744}
79. MligTC455_54106 87 1.81 Mlig455_046338, Mlig455_068234

Neo: Int S/G2/M

Age: Up-Down-Down

PLCB1, PLCB3 1.85 - - 0.957 0.893 - -

Mlig455_046338 {REF} {Length: 4577} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=201.8]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=127.9]; PH domain [PF17787.3, score=69.3]; Protein of unknown function (DUF1154) [PF06631.13, score=28.5]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=27.5]} {Human: ENSG00000182621, PLCB1, phospholipase C beta 1, [Score=797, Expect=0.0]; ENSG00000149782, PLCB3, phospholipase C beta 3, [Score=796, Expect=0.0]} {Mouse: ENSMUSG00000051177, Plcb1, phospholipase C, beta 1, [Score=801, Expect=0.0]; ENSMUSG00000024960, Plcb3, phospholipase C, beta 3, [Score=784, Expect=0.0]} {Dmel: FBgn0004611, Plc21C, Phospholipase C at 21C, [Score=418, Expect=4e-125]} {Celegans: WBGene00001177, egl-8, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8, [Score=671, Expect=0.0]} {Smed: dd_Smed_v6_3221_0_1, dd_Smed_v6_3221_0_1, [Score=702, Expect=0.0]} {RNA1509_50989} {RNA1310_17477} {RNA815_25811}

Mlig455_068234 {REF} {Length: 4646} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=201.7]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=127.9]; PH domain [PF17787.3, score=123.2]; Protein of unknown function (DUF1154) [PF06631.13, score=28.5]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=27.4]} {Human: ENSG00000149782, PLCB3, phospholipase C beta 3, [RH, Score=837, Expect=0.0]; ENSG00000182621, PLCB1, phospholipase C beta 1, [RH, Score=831, Expect=0.0]} {Mouse: ENSMUSG00000051177, Plcb1, phospholipase C, beta 1, [RH, Score=830, Expect=0.0]; ENSMUSG00000024960, Plcb3, phospholipase C, beta 3, [RH, Score=827, Expect=0.0]} {Dmel: FBgn0004611, Plc21C, Phospholipase C at 21C, [Score=444, Expect=7e-134]} {Celegans: WBGene00001177, egl-8, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8, [Score=684, Expect=0.0]} {Smed: dd_Smed_v6_3221_0_2, dd_Smed_v6_3221_0_2, [Score=716, Expect=0.0]} {RNA1509_50989} {RNA1310_17477, RNA1509_50989} {RNA1509_50989, RNA815_25811}
80. MligTC455_33264 88 1.84 Mlig455_055165

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-1.707

SLC17A8 1.849 - - 0.983 - - 0.866 Mlig455_055165 {REF} {Length: 2530} {Pfam: Major Facilitator Superfamily [PF07690.18, score=65.4]} {Human: ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [Score=129, Expect=5e-31]; ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [Score=128, Expect=6e-31]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [Score=124, Expect=1e-29]} {Mouse: ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [Score=130, Expect=1e-31]; ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [Score=130, Expect=2e-31]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [Score=130, Expect=1e-31]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=112, Expect=6e-26]} {Celegans: WBGene00017681, slc-17.5, SLC (SoLute Carrier) homolog, [Score=66.6, Expect=2e-11]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [Score=125, Expect=3e-30]} {RNA1509_54006} {RNA1310_10685, RNA1509_54006} {RNA1509_54006, RNA815_25744}
81. MligTC455_17153 99 2.07 Mlig455_012529

Neo: -

Age: -

CD63 1.848 - - - 0.981 - 0.867 Mlig455_012529 {REF} {Length: 1590} {Pfam: Tetraspanin family [PF00335.22, score=91.4]} {Human: ENSG00000135404, CD63, CD63 molecule, [RH, Score=83.2, Expect=2e-19]} {Mouse: ENSMUSG00000058254, Tspan7, tetraspanin 7, [Score=60.8, Expect=1e-10]} {Dmel: FBgn0033129, Tsp42Eh, Tetraspanin 42Eh, [Score=51.6, Expect=1e-07]} {Celegans: WBGene00006633, tsp-7, Tetraspanin, [Score=59.7, Expect=1e-10]} {Smed: dd_Smed_v6_6981_0_1, dd_Smed_v6_6981_0_1, [RH, Score=115, Expect=2e-31]} {RNA1509_52202} {RNA1310_38549} {RNA815_11397}
82. MligTC455_11698 105 2.19 Mlig455_024131, Mlig455_054470

Neo: -

Age: -

Region-enriched R2: 12.016/0.00001

1.846 - - 1.000 - 0.846 -

Mlig455_024131 {REF} {Length: 399} {RNA1509_2588} {RNA1310_120080} {RNA815_53081}

Mlig455_054470 {REF} {Length: 369} {RNA1509_2588} {RNA1310_120080} {RNA815_53081}
83. MligTC455_48720 1367 28.48 Mlig455_017034

Neo: -

Age: -

Region-specific R2: 4.593

Region-enriched R2: 3.164/0.00157

1.844 - - 0.954 0.890 - - Mlig455_017034 {REF} {Length: 866} {RNA1509_17554, RNA1509_28146} {RNA1310_40772, RNA1509_28146} {RNA1509_28146, RNA815_29897}
84. MligTC455_46777 1781 37.1 Mlig455_004263, Mlig455_004313, Mlig455_004332

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.342

Region-specific R2: 8.084

Region-enriched R2: 11.704/0.00000

1.84 - - 0.996 - 0.844 -

Mlig455_004263 {REF} {Length: 893} {RNA1509_28081} {RNA1310_35014} {RNA815_16619}

Mlig455_004313 {REF} {Length: 901} {RNA1509_15156} {RNA1310_35014} {RNA815_16619}

Mlig455_004332 {REF} {Length: 1003} {RNA1509_15156, RNA1509_28081} {RNA1310_35014, RNA1509_15156, RNA1509_28081} {RNA1509_15156, RNA1509_28081, RNA815_16619}
85. MligTC455_12113 72 1.5 Mlig455_001687, Mlig455_071131

Neo: -

Age: -

1.837 - - 0.991 0.846 - -

Mlig455_001687 {REF} {Length: 809} {RNA1310_67367} {RNA815_37220}

Mlig455_071131 {REF} {Length: 452} {RNA1509_45496} {RNA1310_67367} {RNA815_37220}
86. MligTC455_18888 63 1.31 Mlig455_011646, Mlig455_049904

Neo: -

Age: Up-Up-Down

1.835 - - 1.000 - 0.835 -

Mlig455_011646 {REF} {Length: 92} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_37293} {RNA1310_21789} {RNA815_13092}

Mlig455_049904 {REF} {Length: 92} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_37293} {RNA1310_21789} {RNA815_13092}
87. MligTC455_39392 3 0.05 Mlig455_042341

Neo: -

Age: -

1.835 - - 1.000 - 0.835 - Mlig455_042341 {REF} {Length: 943} {Pfam: PAN domain [PF00024.28, score=20.9]} {RNA1509_56220} {RNA1310_77268} {RNA815_27180}
88. MligTC455_20114 4655 96.97 Mlig455_032750

Neo: -

Age: -

Region-enriched R2: 6.812/0.00000
Region-enriched R3: 5.878/0.00000

ADAMTS7 1.834 - - - 0.881 - 0.953 Mlig455_032750 {REF} {Length: 1794} {Pfam: Metallo-peptidase family M12 [PF13688.8, score=51.5]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=44.0]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=39.8]; Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=37.0]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=26.8]; ADAM cysteine-rich domain [PF17771.3, score=26.3]; Astacin (Peptidase family M12A) [PF01400.26, score=18.3]} {Human: ENSG00000136378, ADAMTS7, ADAM metallopeptidase with thrombospondin type 1 motif 7, [Score=72.4, Expect=1e-12]; ENSG00000134917, ADAMTS8, ADAM metallopeptidase with thrombospondin type 1 motif 8, [Score=72.0, Expect=1e-12]} {Mouse: ENSMUSG00000058145, Adamts17, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17, [Score=70.5, Expect=3e-12]; ENSMUSG00000031994, Adamts8, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8, [Score=70.1, Expect=3e-12]; ENSMUSG00000046169, Adamts6, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6, [Score=69.7, Expect=4e-12]; ENSMUSG00000049538, Adamts16, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16, [Score=68.2, Expect=1e-11]; ENSMUSG00000006403, Adamts4, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4, [Score=67.4, Expect=2e-11]} {Dmel: FBgn0029791, CG4096, [Score=74.3, Expect=1e-13]} {Celegans: WBGene00003248, mig-17, ADAM family mig-17, [Score=58.5, Expect=6e-09]} {RNA1509_811} {RNA1310_18102.1, RNA1509_811} {RNA1509_811, RNA815_7066}
89. MligTC455_20113 4626 96.37 Mlig455_032728

Neo: -

Age: -

Region-enriched R2: 7.104/0.00000
Region-enriched R3: 6.207/0.00000

ADAMTS4 1.833 - - - 0.881 - 0.952 Mlig455_032728 {REF} {Length: 1834} {Pfam: Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=34.1]; Metallo-peptidase family M12 [PF13688.8, score=30.1]} {Human: ENSG00000158859, ADAMTS4, ADAM metallopeptidase with thrombospondin type 1 motif 4, [Score=50.1, Expect=3e-06]; ENSG00000154734, ADAMTS1, ADAM metallopeptidase with thrombospondin type 1 motif 1, [Score=48.1, Expect=3e-06]} {Mouse: ENSMUSG00000006403, Adamts4, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4, [Score=50.1, Expect=2e-06]} {RNA1509_811} {RNA1310_18102.1} {RNA815_7066}
90. MligTC455_37988 67 1.41 Mlig455_008561

Neo: -

Age: -

Region-enriched R2: 8.988/0.00000

1.832 - - 0.974 0.858 - - Mlig455_008561 {REF} {Length: 3146} {Pfam: EF-hand domain pair [PF13499.8, score=36.5]; EF-hand domain [PF13405.8, score=31.2]; EF hand [PF00036.34, score=29.3]; EF-hand domain pair [PF13833.8, score=20.4]; EF hand [PF13202.8, score=19.4]} {Smed: dd_Smed_v6_1010_0_1, dd_Smed_v6_1010_0_1, [Score=104, Expect=1e-26]} {RNA1310_31713.1} {RNA815_36423}
91. MligTC455_40791 75 1.56 Mlig455_013501

Neo: -

Age: -

Region-enriched R2: 7.804/0.01222

1.822 - - 0.963 0.859 - - Mlig455_013501 {REF} {Length: 2310} {Pfam: WSC domain [PF01822.21, score=57.5]; F5/8 type C domain [PF00754.27, score=52.4]; Clip-domain serine protease homolog Scarface [PF18399.3, score=20.3]} {Smed: dd_Smed_v6_52492_0_1, dd_Smed_v6_52492_0_1, [Score=58.5, Expect=2e-10]} {RNA1509_16751} {RNA1310_14302.1} {RNA815_6113.1}
92. MligTC455_46903 255 5.3 Mlig455_040553

Neo: -

Age: -

Region-enriched R2: 9.597/0.00026

1.818 - - 0.991 0.827 - - Mlig455_040553 {REF} {Length: 562} {RNA1509_45949} {RNA1310_70304, RNA1509_45949} {RNA1509_45949, RNA815_37653}
93. MligTC455_46502 168 3.5 Mlig455_010557

Neo: -

Age: -

1.816 - - 0.983 0.833 - - Mlig455_010557 {REF} {Length: 557} {Pfam: HalX domain [PF08663.12, score=24.3]} {RNA1509_57107} {RNA1310_80026, RNA1509_57107} {RNA1509_57107, RNA815_41799}
94. MligTC455_31114 53 1.1 Mlig455_017272

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.386

SLC10A2 1.813 - - 0.970 - 0.843 - Mlig455_017272 {REF} {Length: 2348} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=113.6]; SBF-like CPA transporter family (DUF4137) [PF13593.8, score=38.7]} {Human: ENSG00000125255, SLC10A2, solute carrier family 10 member 2, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [RH, Score=155, Expect=7e-43]} {Dmel: FBgn0030638, CG11655, [Score=157, Expect=7e-43]} {Celegans: WBGene00044650, Y71G10AR.4, [Score=180, Expect=9e-51]} {Smed: dd_Smed_v6_14676_0_1, dd_Smed_v6_14676_0_1, [Score=260, Expect=5e-82]} {RNA1509_52848} {RNA1310_31875.1} {RNA815_14501}
95. MligTC455_03731 113 2.35 Mlig455_066791

Neo: -

Age: -

1.807 - - 0.989 0.818 - - Mlig455_066791 {REF} {Length: 1679} {Smed: dd_Smed_v6_13648_0_1, dd_Smed_v6_13648_0_1, [RH, Score=79.7, Expect=2e-16]} {RNA1509_58026} {RNA1310_23180, RNA1509_58026} {RNA1509_58026, RNA815_34008}
96. MligTC455_41571 277 5.77 Mlig455_024103

Neo: -

Age: -

Region-enriched R2: 6.275/0.00003

SULT1C3 1.805 - - 0.955 - 0.850 - Mlig455_024103 {REF} {Length: 1438} {TRANSSPLICED} {Pfam: Sulfotransferase domain [PF00685.29, score=136.6]; Sulfotransferase family [PF13469.8, score=29.1]} {Human: ENSG00000196228, SULT1C3, sulfotransferase family 1C member 3, [Score=119, Expect=8e-31]; ENSG00000197165, SULT1A2, sulfotransferase family 1A member 2, [Score=118, Expect=1e-30]; ENSG00000138068, SULT6B1, sulfotransferase family 6B member 1, [Score=118, Expect=2e-30]; ENSG00000198203, SULT1C2, sulfotransferase family 1C member 2, [Score=115, Expect=2e-29]} {Mouse: ENSMUSG00000038045, Sult6b1, sulfotransferase family, cytosolic, 6B, member 1, [RH, Score=125, Expect=2e-33]} {Dmel: FBgn0037665, St2, Sulfotransferase 2, [Score=108, Expect=5e-27]} {Celegans: WBGene00013748, ssu-1, Suppressor of Stomatin mutant Uncoordination, [Score=109, Expect=5e-27]} {Smed: dd_Smed_v6_38079_0_1, dd_Smed_v6_38079_0_1, [Score=102, Expect=3e-25]} {RNA1509_50382, RNA1509_59532} {RNA1310_7046.1, RNA1509_50382, RNA1509_59532} {RNA1509_50382, RNA1509_59532, RNA815_2250.1}
97. MligTC455_51429 110 2.29 Mlig455_024820, Mlig455_024899

Neo: -

Age: Up-Down-Down

KCNK18 1.805 - - 0.985 0.820 - -

Mlig455_024820 {REF} {Length: 2654} {Pfam: Ion channel [PF07885.18, score=117.7]; Ion transport protein [PF00520.33, score=25.7]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [RH, Score=102, Expect=6e-23]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=7e-23]; ENSMUSG00000033854, Kcnk10, potassium channel, subfamily K, member 10, [Score=97.8, Expect=3e-21]} {Dmel: FBgn0033257, sand, sandman, [RH, Score=159, Expect=1e-43]} {Celegans: WBGene00010784, twk-48, TWiK family of potassium channels, [Score=171, Expect=4e-48]} {Smed: dd_Smed_v6_19825_0_1, dd_Smed_v6_19825_0_1, [RH, Score=333, Expect=5e-110]} {RNA1509_56216} {RNA1310_14699.1, RNA1509_56216} {RNA1509_56216, RNA815_23055}

Mlig455_024899 {REF} {Length: 3465} {Pfam: Ion channel [PF07885.18, score=115.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=113.8]; Ion transport protein [PF00520.33, score=23.7]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [RH, Score=101, Expect=2e-22]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=2e-22]; ENSMUSG00000033854, Kcnk10, potassium channel, subfamily K, member 10, [Score=97.4, Expect=1e-20]} {Dmel: FBgn0033257, sand, sandman, [RH, Score=159, Expect=3e-42]} {Celegans: WBGene00010784, twk-48, TWiK family of potassium channels, [Score=170, Expect=2e-46]} {Smed: dd_Smed_v6_19825_0_1, dd_Smed_v6_19825_0_1, [RH, Score=333, Expect=3e-106]} {RNA1509_56216} {RNA1310_14699.1} {RNA815_252.1}
98. MligTC455_32575 62 1.29 Mlig455_024198

Neo: -

Age: logFC(26M/2M)=-0.353

FAT4 1.798 - - 0.979 0.819 - - Mlig455_024198 {REF} {Length: 7971} {Pfam: Cadherin domain [PF00028.19, score=704.5]; Cadherin-like [PF16184.7, score=77.6]; Cadherin-like [PF08266.14, score=39.5]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=501, Expect=3e-142]; ENSG00000107736, CDH23, cadherin related 23, [Score=498, Expect=1e-141]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=514, Expect=1e-146]; ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=504, Expect=1e-143]} {Dmel: FBgn0284247, ds, dachsous, [Score=457, Expect=3e-129]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=277, Expect=2e-74]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=276, Expect=8e-74]} {RNA1509_24504} {RNA1310_3168, RNA1509_24504} {RNA1509_24504, RNA815_13217}
99. MligTC455_02258 14 0.29 Mlig455_004819, Mlig455_004888, Mlig455_004900

Neo: -

Age: -

SLC9B2 1.797 - - 1.000 0.797 - -

Mlig455_004819 {REF} {Length: 2596} {Pfam: Sodium/hydrogen exchanger family [PF00999.23, score=54.1]} {Human: ENSG00000164038, SLC9B2, solute carrier family 9 member B2, [Score=125, Expect=5e-31]; ENSG00000164037, SLC9B1, solute carrier family 9 member B1, [Score=119, Expect=4e-29]} {Mouse: ENSMUSG00000050150, Slc9b1, solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1, [Score=128, Expect=4e-32]; ENSMUSG00000037994, Slc9b2, solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2, [Score=128, Expect=3e-32]} {Dmel: FBgn0031865, Nha1, Na[+]/H[+] hydrogen antiporter 1, [Score=115, Expect=1e-27]} {Celegans: WBGene00009618, F41E7.2, [Score=52.8, Expect=3e-07]} {Smed: dd_Smed_v6_7736_0_1, dd_Smed_v6_7736_0_1, [Score=126, Expect=1e-33]} {RNA1310_33802}

Mlig455_004888 {REF} {Length: 2402} {Pfam: Sodium/hydrogen exchanger family [PF00999.23, score=115.6]} {Human: ENSG00000164038, SLC9B2, solute carrier family 9 member B2, [Score=325, Expect=5e-102]} {Mouse: ENSMUSG00000050150, Slc9b1, solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1, [RH, Score=326, Expect=6e-102]} {Dmel: FBgn0031865, Nha1, Na[+]/H[+] hydrogen antiporter 1, [RH, Score=289, Expect=1e-86]} {Celegans: WBGene00009618, F41E7.2, [Score=138, Expect=3e-34]} {Smed: dd_Smed_v6_7736_0_2, dd_Smed_v6_7736_0_2, [RH, Score=361, Expect=1e-116]} {RNA1310_33802}

Mlig455_004900 {REF} {Length: 3013} {Pfam: Sodium/hydrogen exchanger family [PF00999.23, score=115.6]} {Human: ENSG00000164038, SLC9B2, solute carrier family 9 member B2, [Score=325, Expect=6e-102]} {Mouse: ENSMUSG00000050150, Slc9b1, solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1, [RH, Score=326, Expect=5e-102]} {Dmel: FBgn0031865, Nha1, Na[+]/H[+] hydrogen antiporter 1, [RH, Score=289, Expect=2e-86]} {Celegans: WBGene00009618, F41E7.2, [Score=139, Expect=2e-34]} {Smed: dd_Smed_v6_7736_0_2, dd_Smed_v6_7736_0_2, [RH, Score=361, Expect=2e-116]} {RNA1509_37253} {RNA1310_95649} {RNA815_29346.1}
100. MligTC455_53633 1960 40.84 Mlig455_043831, Mlig455_047417, Mlig455_070992

Neo: -

Age: -

Region-specific R2: 8.211

Region-enriched R2: 9.874/0.00000

1.797 - - 0.998 0.799 - -

Mlig455_043831 {REF} {Length: 1456} {RNA1509_16856} {RNA1310_25970.1, RNA1509_16856} {RNA1509_16856, RNA815_11970}

Mlig455_047417 {REF} {Length: 1354} {RNA1509_16856} {RNA1310_25970.1} {RNA815_11970}

Mlig455_070992 {REF} {Length: 1455} {RNA1509_16856} {RNA1310_25970.1} {RNA815_11970}

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