Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_44241 | 669 | 13.93 | Mlig455_036732 | Neo: - Age: - Region-enriched R2: 1.413/0.00826 |
Mlig455_036732 {REF} {Length: 1678} {Pfam: Universal stress protein family [PF00582.28, score=92.2]} {Smed: dd_Smed_v6_1092_0_1, dd_Smed_v6_1092_0_1, [Score=111, Expect=1e-31]} {RNA1509_25843} {RNA1310_29557.1} {RNA815_18242} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -1.255 | 4.018 | 0.33912 | 0.98424 | |
RegionR2 | 1.413 | 4.018 | 0.00027 | 0.00826 | |
RegionR3 | 0.167 | 4.018 | 0.63030 | 1.00000 | |
RegionR4 | -0.45 | 4.018 | 0.33427 | 0.65294 | |
RegionR5 | -1.135 | 4.018 | 0.00955 | 0.05577 | |
RegionR6 | -0.199 | 4.018 | 0.61796 | 1.00000 | |
RegionR7 | 1.049 | 4.018 | 0.01035 | 0.17498 | |
RegionR8 | 0.41 | 4.018 | 0.44379 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -5.65 | 4.018 | 0.28087 | 0.98107 | |
RegenerationR2 | -0.509 | 4.018 | 0.08465 | 0.46728 | |
RegenerationR3 | -0.468 | 4.018 | 0.22685 | 0.66196 | |
RegenerationR4 | -0.02 | 4.018 | 0.96235 | 1.00000 | |
RegenerationR5 | 0.086 | 4.018 | 0.83834 | 1.00000 | |
RegenerationR6 | 0.292 | 4.018 | 0.48282 | 0.79348 | |
RegenerationBL | 0.393 | 4.018 | 0.36335 | 0.73184 | |
RegenerationTP | 0.314 | 4.018 | 0.47385 | 0.88338 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_44241 | 669 | 13.93 | Mlig455_036732 | Neo: - Age: - Region-enriched R2: 1.413/0.00826 |
6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_036732 {REF} {Length: 1678} {Pfam: Universal stress protein family [PF00582.28, score=92.2]} {Smed: dd_Smed_v6_1092_0_1, dd_Smed_v6_1092_0_1, [Score=111, Expect=1e-31]} {RNA1509_25843} {RNA1310_29557.1} {RNA815_18242} | |
2. | MligTC455_40882 | 435 | 9.07 | Mlig455_059173 | Neo: - Age: - |
GAD1 | 2.676 | - | 0.960 | 0.836 | - | - | 0.880 | Mlig455_059173 {REF} {Length: 3488} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=391.1]} {Human: ENSG00000128683, GAD1, glutamate decarboxylase 1, [RH, Score=659, Expect=0.0]} {Mouse: ENSMUSG00000070880, Gad1, glutamate decarboxylase 1, [RH, Score=659, Expect=0.0]} {Dmel: FBgn0004516, Gad1, Glutamic acid decarboxylase 1, [RH, Score=558, Expect=0.0]} {Celegans: WBGene00006762, unc-25, Glutamic acid decarboxylase, [RH, Score=595, Expect=0.0]} {Smed: dd_Smed_v6_12653_0_1, dd_Smed_v6_12653_0_1, [RH, Score=666, Expect=0.0]} {RNA1509_17310} {RNA1310_9376} {RNA815_16779} |
3. | MligTC455_35294 | 1547 | 32.23 | Mlig455_001167, Mlig455_001326, Mlig455_070580 | Neo: - Age: Down-Up-Up Region-enriched R8: 1.741/0.00233 |
GRIA2, GRID1 | 2.633 | - | 0.846 | 0.974 | 0.813 | - | - | Mlig455_001167 {REF} {Length: 3625} {Pfam: Ligand-gated ion channel [PF00060.28, score=89.8]; Universal stress protein family [PF00582.28, score=80.5]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=33.4]; Receptor family ligand binding region [PF01094.30, score=23.9]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.3]} {Human: ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=123, Expect=6e-28]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=120, Expect=3e-27]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=117, Expect=5e-26]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=123, Expect=3e-28]; ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=117, Expect=4e-26]} {Dmel: FBgn0038837, CG3822, [Score=124, Expect=9e-29]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=113, Expect=2e-25]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=220, Expect=2e-63]} {RNA1509_17988} {RNA1310_23557} {RNA815_11623.1} Mlig455_001326 {REF} {Length: 3494} {Pfam: Ligand-gated ion channel [PF00060.28, score=92.1]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=33.4]; Receptor family ligand binding region [PF01094.30, score=23.1]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.8]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=121, Expect=2e-27]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=118, Expect=2e-26]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=124, Expect=2e-28]} {Dmel: FBgn0038840, Grik, [Score=125, Expect=7e-29]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=114, Expect=1e-25]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=220, Expect=9e-64]} {RNA1509_17988} {RNA1310_23557} {RNA815_11623.1} Mlig455_070580 {REF} {Length: 3686} {Pfam: Ligand-gated ion channel [PF00060.28, score=92.1]; Universal stress protein family [PF00582.28, score=80.3]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=33.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=33.2]; Receptor family ligand binding region [PF01094.30, score=22.8]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=125, Expect=1e-28]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=128, Expect=1e-29]} {Dmel: FBgn0038837, CG3822, [Score=135, Expect=4e-32]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=119, Expect=4e-27]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=237, Expect=2e-69]} {RNA1509_17988} {RNA1310_23557} {RNA815_11623.1} |
4. | MligTC455_18787 | 963 | 20.06 | Mlig455_014022 | Neo: - Age: - Region-enriched R2: 1.334/0.03482 |
STRC | 2.455 | 0.761 | - | 0.956 | - | - | 0.738 | Mlig455_014022 {REF} {Length: 5754} {Human: ENSG00000242866, STRC, stereocilin, [RH, Score=76.3, Expect=4e-13]} {Mouse: ENSMUSG00000033498, Strc, stereocilin, [RH, Score=80.9, Expect=1e-14]} {RNA1509_4378} {RNA1310_1493.1, RNA1509_4378} {RNA1509_4378, RNA815_804} |
5. | MligTC455_51314 | 525 | 10.93 | Mlig455_017296, Mlig455_045285 | Neo: - Age: - Region-enriched R2: 2.314/0.04004 |
2.435 | 0.720 | 0.739 | - | - | - | 0.976 | Mlig455_017296 {REF} {Length: 2087} {RNA1310_34789} {RNA815_64894} Mlig455_045285 {REF} {Length: 1644} {RNA1310_34789} {RNA815_64894} |
|
6. | MligTC455_07623 | 797 | 16.6 | Mlig455_048459 | Neo: - Age: Down-Up-Down |
STOM | 1.898 | - | 0.954 | - | - | - | 0.944 | Mlig455_048459 {REF} {Length: 2249} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=40.3]} {Human: ENSG00000148175, STOM, stomatin, [Score=157, Expect=4e-48]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=159, Expect=3e-49]} {Dmel: FBgn0260657, CG42540, [Score=158, Expect=1e-47]} {Celegans: WBGene00006068, sto-6, STOmatin, [Score=159, Expect=5e-49]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=185, Expect=1e-59]} {RNA1509_9137} {RNA1310_11482.1} {RNA815_6842} |
7. | MligTC455_40653 | 608 | 12.66 | Mlig455_001674 | Neo: - Age: - Region-enriched R2: 1.468/0.01853 |
1.855 | - | 0.872 | - | - | - | 0.983 | Mlig455_001674 {REF} {Length: 2361} {TRANSSPLICED} {Pfam: Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=51.2]; Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=48.0]} {Smed: dd_Smed_v6_8715_0_1, dd_Smed_v6_8715_0_1, [Score=50.8, Expect=1e-06]} {RNA1509_19981, RNA1509_43006} {RNA1310_9812, RNA1509_19981, RNA1509_43006} {RNA1509_19981, RNA1509_43006, RNA815_12879} | |
8. | MligTC455_52325 | 682 | 14.2 | Mlig455_061124 | Neo: - Age: logFC(26M/2M)=-0.271 Regeneration-downregulated BL: -1.826 Regeneration-depleted BL: -1.826 |
1.827 | - | 0.952 | - | - | - | 0.875 | Mlig455_061124 {REF} {Length: 9447} {Pfam: Fibrinogen binding protein [PF08017.13, score=176.9]} {RNA1509_13352, RNA1509_42393, RNA1509_55215, RNA1509_58455} {RNA1310_7913, RNA1509_13352, RNA1509_42393, RNA1509_55215, RNA1509_58455} {RNA1509_13352, RNA1509_42393, RNA1509_55215, RNA1509_58455, RNA815_2288} | |
9. | MligTC455_23269 | 1700 | 35.41 | Mlig455_058823 | Neo: - Age: - Region-enriched R8: 1.965/0.00066 |
SYT1 | 1.823 | - | 0.851 | - | - | - | 0.972 | Mlig455_058823 {REF} {Length: 3328} {Pfam: C2 domain [PF00168.32, score=181.3]; CEP76 C2 domain [PF15627.8, score=21.0]; Phosphoinositide 3-kinase C2 [PF00792.26, score=20.4]} {Human: ENSG00000067715, SYT1, synaptotagmin 1, [RH, Score=436, Expect=4e-151]} {Mouse: ENSMUSG00000035864, Syt1, synaptotagmin I, [RH, Score=435, Expect=4e-151]} {Dmel: FBgn0004242, Syt1, Synaptotagmin 1, [Score=496, Expect=1e-174]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=432, Expect=6e-150]} {Smed: dd_Smed_v6_6730_0_1, dd_Smed_v6_6730_0_1, [Score=542, Expect=0.0]} {RNA1509_10517, RNA1509_25740, RNA1509_36281, RNA1509_40080} {RNA1310_21689, RNA1509_10517, RNA1509_25740, RNA1509_36281, RNA1509_40080} {RNA1509_10517, RNA1509_25740, RNA1509_36281, RNA1509_40080, RNA815_10622.1} |
10. | MligTC455_44264 | 1135 | 23.65 | Mlig455_048455, Mlig455_062720 | Neo: - Age: - Region-specific R2: 2.470 Region-enriched R2: 1.517/0.00960 |
1.752 | - | 0.802 | 0.950 | - | - | - | Mlig455_048455 {REF} {Length: 2873} {Pfam: Borrelia P83/100 protein [PF05262.13, score=18.8]} {Smed: dd_Smed_v6_19428_0_1, dd_Smed_v6_19428_0_1, [RH, Score=76.6, Expect=5e-15]} {RNA1509_14284} {RNA1310_10721, RNA1509_14284} {RNA1509_14284, RNA815_3648} Mlig455_062720 {REF} {Length: 2364} {Pfam: Borrelia P83/100 protein [PF05262.13, score=19.7]} {Smed: dd_Smed_v6_19428_0_1, dd_Smed_v6_19428_0_1, [RH, Score=78.2, Expect=2e-15]} {RNA1509_14284, RNA1509_52018} {RNA1310_10721, RNA1509_52018} {RNA1509_52018, RNA815_3648} |
|
11. | MligTC455_42967 | 296 | 6.17 | Mlig455_002749, Mlig455_011489 | Neo: - |
1.683 | 0.711 | - | - | - | - | 0.972 | Mlig455_002749 {REF} {Length: 1700} {RNA1509_21752} {RNA1310_30402.1} {RNA815_26388} Mlig455_011489 {REF} {Length: 1762} {RNA1509_21752, RNA1509_6543} {RNA1310_30402.1, RNA1509_6543} {RNA1509_6543, RNA815_26388} |
|
12. | MligTC455_46583 | 1098 | 22.87 | Mlig455_067509 | Neo: - Age: logFC(26M/2M)=-0.318 Region-enriched R8: 2.830/0.00000 Regeneration-depleted TP: -3.677 |
0.963 | - | - | - | - | - | 0.963 | Mlig455_067509 {REF} {Length: 1536} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=25.3]} {Dmel: FBgn0051221, CG31221, [Score=62.8, Expect=5e-12]} {Celegans: WBGene00010290, F58H1.7, [RH, Score=66.6, Expect=1e-13]} {Smed: dd_Smed_v6_2598_0_1, dd_Smed_v6_2598_0_1, [RH, Score=173, Expect=3e-55]} {RNA1509_59060} {RNA1310_28256} {RNA815_15141.1} | |
13. | MligTC455_20838 | 235 | 4.89 | Mlig455_022987 | Neo: - Age: - |
H6PD | 0.959 | - | - | - | - | - | 0.959 | Mlig455_022987 {REF} {Length: 2684} {TRANSSPLICED} {Pfam: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase [PF01182.22, score=105.1]; Glucose-6-phosphate dehydrogenase, C-terminal domain [PF02781.18, score=96.2]; Glucose-6-phosphate dehydrogenase, NAD binding domain [PF00479.24, score=82.3]} {Human: ENSG00000049239, H6PD, hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase, [Score=210, Expect=1e-56]} {Mouse: ENSMUSG00000028980, H6pd, hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase), [Score=222, Expect=5e-61]} {Dmel: FBgn0004057, Zw, Zwischenferment, [Score=142, Expect=3e-35]} {Celegans: WBGene00007108, gspd-1, Glucose-6-phosphate 1-dehydrogenase, [Score=133, Expect=1e-32]} {Smed: dd_Smed_v6_2965_0_1, dd_Smed_v6_2965_0_1, [Score=132, Expect=2e-32]} {RNA1509_16416} {RNA1310_9105, RNA1509_16416} {RNA1509_16416, RNA815_2264.1} |
14. | MligTC455_43643 | 2324 | 48.41 | Mlig455_065102 | Neo: - Age: - Region-specific R2: 2.496 Region-enriched R2: 1.834/0.00001 Regeneration-downregulated R6: -1.642 Regeneration-depleted R6: -1.642 |
0.958 | - | - | 0.958 | - | - | - | Mlig455_065102 {REF} {Length: 850} {RNA1509_16353, RNA1509_24268} {RNA1310_47277.1, RNA1509_24268} {RNA1509_24268, RNA815_19145.2} | |
15. | MligTC455_38341 | 247 | 5.16 | Mlig455_063905 | Neo: - Age: logFC(26M/2M)=0.521 |
0.957 | - | - | - | - | - | 0.957 | Mlig455_063905 {REF} {Length: 3946} {Mouse: ENSMUSG00000026579, F5, coagulation factor V, [Score=50.8, Expect=3e-06]} {RNA1509_22375} {RNA1310_52447} {RNA815_8374.2} | |
16. | MligTC455_13764 | 175 | 3.65 | Mlig455_010818 | Neo: - Age: - |
0.953 | - | - | - | - | - | 0.953 | Mlig455_010818 {REF} {Length: 1953} {RNA1509_22845} {RNA1310_11632} {RNA815_10000} | |
17. | MligTC455_15531 | 235 | 4.89 | Mlig455_047388 | Neo: - Age: - Region-enriched R2: 3.376/0.02120 |
PCDH1 | 0.951 | - | - | - | 0.951 | - | - | Mlig455_047388 {REF} {Length: 4578} {Pfam: Cadherin domain [PF00028.19, score=151.1]; Cadherin-like [PF16184.7, score=34.7]} {Human: ENSG00000156453, PCDH1, protocadherin 1, [Score=194, Expect=2e-49]} {Mouse: ENSMUSG00000051375, Pcdh1, protocadherin 1, [Score=194, Expect=7e-50]} {Dmel: FBgn0024836, stan, starry night, [Score=166, Expect=6e-41]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=127, Expect=5e-29]} {Smed: dd_Smed_v6_21207_0_1, dd_Smed_v6_21207_0_1, [Score=266, Expect=2e-73]} {RNA1509_29466} {RNA1310_2382, RNA1509_29466} {RNA1509_29466, RNA815_20993} |