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Results for MligTC455_44416

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_44416 201 4.18 Mlig455_024126, Mlig455_054466

Neo: Neoblast, stringent

Age: -

Regeneration-upregulated R6: 2.683

Regeneration-enriched R6: 2.683

 TOP2A

Mlig455_024126 {REF} {Length: 5435} {TRANSSPLICED} {Pfam: DNA gyrase/topoisomerase IV, subunit A [PF00521.22, score=407.2]; C-terminal associated domain of TOPRIM [PF16898.7, score=149.4]; DNA gyrase B [PF00204.27, score=73.4]; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase [PF02518.28, score=57.0]; Toprim domain [PF01751.24, score=32.9]} {Human: ENSG00000131747, TOP2A, DNA topoisomerase II alpha, [Score=1313, Expect=0.0]; ENSG00000077097, TOP2B, DNA topoisomerase II beta, [Score=1296, Expect=0.0]} {Mouse: ENSMUSG00000020914, Top2a, topoisomerase (DNA) II alpha, [Score=1323, Expect=0.0]; ENSMUSG00000017485, Top2b, topoisomerase (DNA) II beta, [Score=1293, Expect=0.0]} {Dmel: FBgn0284220, Top2, Topoisomerase 2, [Score=1226, Expect=0.0]} {Celegans: WBGene00010785, top-2, Probable DNA topoisomerase 2, [Score=1201, Expect=0.0]} {Smed: dd_Smed_v6_1626_0_2, dd_Smed_v6_1626_0_2, [Score=1205, Expect=0.0]} {RNA1509_2428} {RNA1310_1442} {RNA815_409}

Mlig455_054466 {REF} {Length: 540} {TRANSSPLICED} {Human: ENSG00000131747, TOP2A, DNA topoisomerase II alpha, [Score=160, Expect=1e-45]} {Mouse: ENSMUSG00000020914, Top2a, topoisomerase (DNA) II alpha, [Score=161, Expect=4e-46]} {Dmel: FBgn0284220, Top2, Topoisomerase 2, [Score=142, Expect=2e-39]} {Celegans: WBGene00010785, top-2, Probable DNA topoisomerase 2, [Score=147, Expect=3e-41]} {Smed: dd_Smed_v6_1626_0_3, dd_Smed_v6_1626_0_3, [Score=130, Expect=1e-35]} {RNA1509_2428} {RNA1310_1442} {RNA815_409}

Cumulative graph for MligTC455_44416

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.394 2.594 0.75859 1.00000
RegionR2 -0.498 2.594 0.93872 1.00000
RegionR3 0.744 2.594 0.36613 0.90081
RegionR4 2.067 2.594 0.00942 0.05835
RegionR5 1.236 2.594 0.09618 0.29727
RegionR6 0.378 2.594 0.61458 1.00000
RegionR7 0.852 2.594 0.42376 1.00000
RegionR8 -5.174 2.594 0.08966 0.56644

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -4.701 2.594 0.44332 1.00000
RegenerationR2 0.113 2.594 0.89528 1.00000
RegenerationR3 1.052 2.594 0.10937 0.52126
RegenerationR4 0.81 2.594 0.19070 0.63488
RegenerationR5 1.612 2.594 0.00248 0.08691
RegenerationR6 2.683 2.594 0.00006 0.00622 Specific for R6: 2.683
RegenerationBL 3.45 2.594 0.00268 0.04372
RegenerationTP 3.552 2.594 0.03193 0.29964


Genes with expression patterns similar to MligTC455_44416

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_44416 201 4.18 Mlig455_024126, Mlig455_054466

Neo: Neoblast, stringent

Age: -

Regeneration-upregulated R6: 2.683

Regeneration-enriched R6: 2.683

 TOP2A 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_024126 {REF} {Length: 5435} {TRANSSPLICED} {Pfam: DNA gyrase/topoisomerase IV, subunit A [PF00521.22, score=407.2]; C-terminal associated domain of TOPRIM [PF16898.7, score=149.4]; DNA gyrase B [PF00204.27, score=73.4]; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase [PF02518.28, score=57.0]; Toprim domain [PF01751.24, score=32.9]} {Human: ENSG00000131747, TOP2A, DNA topoisomerase II alpha, [Score=1313, Expect=0.0]; ENSG00000077097, TOP2B, DNA topoisomerase II beta, [Score=1296, Expect=0.0]} {Mouse: ENSMUSG00000020914, Top2a, topoisomerase (DNA) II alpha, [Score=1323, Expect=0.0]; ENSMUSG00000017485, Top2b, topoisomerase (DNA) II beta, [Score=1293, Expect=0.0]} {Dmel: FBgn0284220, Top2, Topoisomerase 2, [Score=1226, Expect=0.0]} {Celegans: WBGene00010785, top-2, Probable DNA topoisomerase 2, [Score=1201, Expect=0.0]} {Smed: dd_Smed_v6_1626_0_2, dd_Smed_v6_1626_0_2, [Score=1205, Expect=0.0]} {RNA1509_2428} {RNA1310_1442} {RNA815_409}

Mlig455_054466 {REF} {Length: 540} {TRANSSPLICED} {Human: ENSG00000131747, TOP2A, DNA topoisomerase II alpha, [Score=160, Expect=1e-45]} {Mouse: ENSMUSG00000020914, Top2a, topoisomerase (DNA) II alpha, [Score=161, Expect=4e-46]} {Dmel: FBgn0284220, Top2, Topoisomerase 2, [Score=142, Expect=2e-39]} {Celegans: WBGene00010785, top-2, Probable DNA topoisomerase 2, [Score=147, Expect=3e-41]} {Smed: dd_Smed_v6_1626_0_3, dd_Smed_v6_1626_0_3, [Score=130, Expect=1e-35]} {RNA1509_2428} {RNA1310_1442} {RNA815_409}
2. MligTC455_44414 594 12.38 Mlig455_054465

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.220/0.00367
Region-enriched R4: 1.175/0.03476

Regeneration-upregulated R6: 1.867

Regeneration-enriched R6: 1.867

 TOP2A 5.226 0.808 0.916 0.714 0.950 0.887 0.951 Mlig455_054465 {REF} {Length: 4574} {Pfam: DNA gyrase/topoisomerase IV, subunit A [PF00521.22, score=407.9]; C-terminal associated domain of TOPRIM [PF16898.7, score=149.7]; DNA gyrase B [PF00204.27, score=73.7]; Toprim domain [PF01751.24, score=33.3]} {Human: ENSG00000131747, TOP2A, DNA topoisomerase II alpha, [Score=1059, Expect=0.0]; ENSG00000077097, TOP2B, DNA topoisomerase II beta, [Score=1051, Expect=0.0]} {Mouse: ENSMUSG00000020914, Top2a, topoisomerase (DNA) II alpha, [Score=1072, Expect=0.0]; ENSMUSG00000017485, Top2b, topoisomerase (DNA) II beta, [Score=1047, Expect=0.0]} {Dmel: FBgn0284220, Top2, Topoisomerase 2, [Score=981, Expect=0.0]} {Celegans: WBGene00010785, top-2, Probable DNA topoisomerase 2, [Score=969, Expect=0.0]} {Smed: dd_Smed_v6_1626_0_2, dd_Smed_v6_1626_0_2, [Score=983, Expect=0.0]} {RNA1509_2428} {RNA1310_1442} {RNA815_409}
3. MligTC455_46987 185 3.85 Mlig455_026500

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.555

 2.409 - - - 0.720 0.738 0.951 Mlig455_026500 {REF} {Length: 1602} {RNA1310_24230.1} {RNA815_12415}
4. MligTC455_11239 440 9.17 Mlig455_061960

Neo: -

Age: -

 PDCD6 0.965 - - - 0.965 - - Mlig455_061960 {REF} {Length: 1775} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=78.9]; EF-hand domain pair [PF13833.8, score=78.7]; EF-hand domain pair [PF13499.8, score=76.6]; EF-hand domain [PF13405.8, score=73.8]; EF hand [PF13202.8, score=51.4]; EF-hand domain [PF14658.8, score=23.0]} {Human: ENSG00000249915, PDCD6, programmed cell death 6, [RH, Score=229, Expect=6e-77]} {Mouse: ENSMUSG00000021576, Pdcd6, programmed cell death 6, [RH, Score=228, Expect=1e-76]} {Dmel: FBgn0086378, Alg-2, Apoptosis-linked gene-2, [RH, Score=244, Expect=3e-83]} {Celegans: WBGene00019770, M04F3.4, [RH, Score=207, Expect=5e-69]} {Smed: dd_Smed_v6_3585_0_1, dd_Smed_v6_3585_0_1, [RH, Score=253, Expect=3e-87]} {RNA1509_12324} {RNA1310_41711, RNA1509_12324} {RNA1509_12324, RNA815_22756}
5. MligTC455_30043 144 3 Mlig455_067016

Neo: -

Age: Up-Down-Up

 TMEM94 0.962 - - - 0.962 - - Mlig455_067016 {REF} {Length: 5329} {Human: ENSG00000177728, TMEM94, transmembrane protein 94, [RH, Score=206, Expect=6e-53]} {Mouse: ENSMUSG00000020747, Tmem94, transmembrane protein 94, [RH, Score=205, Expect=6e-53]} {Dmel: FBgn0022153, l(2)k05819, lethal (2) k05819, [RH, Score=400, Expect=5e-117]} {Celegans: WBGene00017010, D1007.15, [RH, Score=189, Expect=2e-48]} {Smed: dd_Smed_v6_12358_0_1, dd_Smed_v6_12358_0_1, [RH, Score=325, Expect=5e-93]} {RNA1509_7674} {RNA1310_1886.2} {RNA815_651}
6. MligTC455_41860 7703 160.49 Mlig455_015322, Mlig455_015364, Mlig455_068750

Neo: Neoblast

Age: Down-Up-Up

Regeneration-upregulated BL: 1.222

Regeneration-enriched BL: 1.222

 EIF4A3 0.962 - - - - - 0.962

Mlig455_015322 {REF} {Length: 2393} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=149.7]; Helicase conserved C-terminal domain [PF00271.33, score=108.1]; AAA domain [PF13604.8, score=32.1]; AAA domain [PF13245.8, score=26.6]; Type III restriction enzyme, res subunit [PF04851.17, score=23.4]} {Human: ENSG00000141543, EIF4A3, eukaryotic translation initiation factor 4A3, [RH, Score=691, Expect=0.0]} {Mouse: ENSMUSG00000025580, Eif4a3, eukaryotic translation initiation factor 4A3, [RH, Score=691, Expect=0.0]; ENSMUSG00000107906, Gm5580, predicted pseudogene 5580, [RH, Score=679, Expect=0.0]; ENSMUSG00000094973, Gm8994, predicted gene 8994, [RH, Score=677, Expect=0.0]} {Dmel: FBgn0037573, CG7483, [RH, Score=687, Expect=0.0]} {Celegans: WBGene00022029, Y65B4A.6, [RH, Score=676, Expect=0.0]} {Smed: dd_Smed_v6_737_0_1, dd_Smed_v6_737_0_1, [RH, Score=643, Expect=0.0]} {RNA1509_4083} {RNA1310_16202} {RNA815_5196}

Mlig455_015364 {REF} {Length: 2394} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=149.7]; Helicase conserved C-terminal domain [PF00271.33, score=108.1]; AAA domain [PF13604.8, score=32.1]; AAA domain [PF13245.8, score=26.6]; Type III restriction enzyme, res subunit [PF04851.17, score=23.4]} {Human: ENSG00000141543, EIF4A3, eukaryotic translation initiation factor 4A3, [RH, Score=691, Expect=0.0]} {Mouse: ENSMUSG00000025580, Eif4a3, eukaryotic translation initiation factor 4A3, [RH, Score=691, Expect=0.0]; ENSMUSG00000107906, Gm5580, predicted pseudogene 5580, [RH, Score=679, Expect=0.0]; ENSMUSG00000094973, Gm8994, predicted gene 8994, [RH, Score=678, Expect=0.0]} {Dmel: FBgn0037573, CG7483, [RH, Score=687, Expect=0.0]} {Celegans: WBGene00022029, Y65B4A.6, [RH, Score=676, Expect=0.0]} {Smed: dd_Smed_v6_737_0_1, dd_Smed_v6_737_0_1, [RH, Score=643, Expect=0.0]} {RNA1509_4083} {RNA1310_16202} {RNA815_5196}

Mlig455_068750 {REF} {Length: 1722} {TRANSSPLICED} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=149.8]; Helicase conserved C-terminal domain [PF00271.33, score=108.2]; AAA domain [PF13604.8, score=32.2]; AAA domain [PF13245.8, score=26.7]; Type III restriction enzyme, res subunit [PF04851.17, score=23.5]} {Human: ENSG00000141543, EIF4A3, eukaryotic translation initiation factor 4A3, [RH, Score=691, Expect=0.0]} {Mouse: ENSMUSG00000025580, Eif4a3, eukaryotic translation initiation factor 4A3, [RH, Score=690, Expect=0.0]; ENSMUSG00000107906, Gm5580, predicted pseudogene 5580, [RH, Score=679, Expect=0.0]; ENSMUSG00000094973, Gm8994, predicted gene 8994, [RH, Score=678, Expect=0.0]} {Dmel: FBgn0037573, CG7483, [RH, Score=687, Expect=0.0]} {Celegans: WBGene00022029, Y65B4A.6, [RH, Score=676, Expect=0.0]} {Smed: dd_Smed_v6_737_0_1, dd_Smed_v6_737_0_1, [RH, Score=643, Expect=0.0]} {RNA1509_4083} {RNA1310_16202, RNA1509_4083} {RNA1509_4083, RNA815_5196}
7. MligTC455_48048 304 6.34 Mlig455_065143

Neo: Irradiation

Age: Up-Down-Down

 0.952 - - - - - 0.952 Mlig455_065143 {REF} {Length: 4336} {TRANSSPLICED} {RNA1509_46828} {RNA1310_6402.1, RNA1509_46828} {RNA1509_46828, RNA815_12174}

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