M. lignano Tomo-Seq
Mlig455 transcriptome Search Regeneration Regions Sections Download

Data search


search
Exact
Search

Results for MligTC455_44449

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_44449 1235 25.73 Mlig455_046782, Mlig455_046804, Mlig455_069958

Neo: -

Age: -

Mlig455_046782 {REF} {Length: 3844} {TRANSSPLICED} {Pfam: Coiled-coil protein 142 [PF14923.8, score=60.9]} {Smed: dd_Smed_v6_17993_0_1, dd_Smed_v6_17993_0_1, [RH, Score=174, Expect=2e-44]} {RNA1509_21784} {RNA1310_7746} {RNA815_16917.1}

Mlig455_046804 {REF} {Length: 3964} {TRANSSPLICED} {Pfam: Coiled-coil protein 142 [PF14923.8, score=60.0]} {Smed: dd_Smed_v6_17993_0_1, dd_Smed_v6_17993_0_1, [Score=99.8, Expect=5e-21]} {RNA1509_21784} {RNA1310_7746, RNA1509_21784} {RNA1509_21784, RNA815_16917.1}

Mlig455_069958 {REF} {Length: 3952} {TRANSSPLICED} {Pfam: Coiled-coil protein 142 [PF14923.8, score=60.7]} {Smed: dd_Smed_v6_17993_0_1, dd_Smed_v6_17993_0_1, [Score=97.1, Expect=3e-20]} {RNA1509_21784} {RNA1310_7746} {RNA815_16917.1}

Cumulative graph for MligTC455_44449

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.4 4.887 0.09070 0.64788
RegionR2 0.12 4.887 0.81980 1.00000
RegionR3 -0.129 4.887 0.77239 1.00000
RegionR4 0.489 4.887 0.36089 0.68382
RegionR5 -0.328 4.887 0.45482 0.81689
RegionR6 -0.758 4.887 0.10825 0.60141
RegionR7 -1.342 4.887 0.02676 0.30776
RegionR8 0.547 4.887 0.38810 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -3.522 4.887 0.01388 0.49837
RegenerationR2 0.648 4.887 0.18872 0.63233
RegenerationR3 0.201 4.887 0.70659 0.95015
RegenerationR4 -0.519 4.887 0.36221 0.78842
RegenerationR5 0.634 4.887 0.22856 0.66298
RegenerationR6 0.312 4.887 0.57169 0.85262
RegenerationBL 0.161 4.887 0.76824 1.00000
RegenerationTP -1.045 4.887 0.12816 0.54040


Genes with expression patterns similar to MligTC455_44449

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_44449 1235 25.73 Mlig455_046782, Mlig455_046804, Mlig455_069958

Neo: -

Age: -

 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_046782 {REF} {Length: 3844} {TRANSSPLICED} {Pfam: Coiled-coil protein 142 [PF14923.8, score=60.9]} {Smed: dd_Smed_v6_17993_0_1, dd_Smed_v6_17993_0_1, [RH, Score=174, Expect=2e-44]} {RNA1509_21784} {RNA1310_7746} {RNA815_16917.1}

Mlig455_046804 {REF} {Length: 3964} {TRANSSPLICED} {Pfam: Coiled-coil protein 142 [PF14923.8, score=60.0]} {Smed: dd_Smed_v6_17993_0_1, dd_Smed_v6_17993_0_1, [Score=99.8, Expect=5e-21]} {RNA1509_21784} {RNA1310_7746, RNA1509_21784} {RNA1509_21784, RNA815_16917.1}

Mlig455_069958 {REF} {Length: 3952} {TRANSSPLICED} {Pfam: Coiled-coil protein 142 [PF14923.8, score=60.7]} {Smed: dd_Smed_v6_17993_0_1, dd_Smed_v6_17993_0_1, [Score=97.1, Expect=3e-20]} {RNA1509_21784} {RNA1310_7746} {RNA815_16917.1}
2. MligTC455_48506 710 14.8 Mlig455_030058

Neo: -

Age: Down-Up-Down

 TMEM232 3.407 - - 0.824 0.972 0.835 0.776 Mlig455_030058 {REF} {Length: 2808} {TRANSSPLICED} {Pfam: Transmembrane protein family 232 [PF15877.7, score=258.6]} {Human: ENSG00000186952, TMEM232, transmembrane protein 232, [RH, Score=171, Expect=2e-44]} {Mouse: ENSMUSG00000045036, Tmem232, transmembrane protein 232, [RH, Score=181, Expect=6e-48]} {Smed: dd_Smed_v6_15138_0_1, dd_Smed_v6_15138_0_1, [RH, Score=163, Expect=1e-42]} {RNA1509_11088} {RNA1310_8942.1, RNA1509_11088} {RNA1509_11088, RNA815_6522}
3. MligTC455_53091 542 11.29 Mlig455_061253

Neo: -

Age: -

 SPATA1 3.296 0.750 - - 0.953 0.836 0.757 Mlig455_061253 {REF} {Length: 3411} {Pfam: Spermatogenesis-associated C-terminus [PF15743.7, score=145.3]} {Human: ENSG00000122432, SPATA1, spermatogenesis associated 1, [Score=108, Expect=2e-24]} {Mouse: ENSMUSG00000028188, Spata1, spermatogenesis associated 1, [Score=110, Expect=4e-25]} {Smed: dd_Smed_v6_15381_0_1, dd_Smed_v6_15381_0_1, [RH, Score=174, Expect=1e-46]} {RNA1509_56521} {RNA1310_8534} {RNA815_3401.1}
4. MligTC455_29437 897 18.69 Mlig455_049319, Mlig455_049403

Neo: -

Age: -

Region-enriched R8: 2.720/0.00033
Region-enriched R7: 1.911/0.02272

Regeneration-depleted TP: -2.721

 PKDREJ 2.632 - - - 0.814 0.976 0.842

Mlig455_049319 {REF} {Length: 10561} {Pfam: Polycystin cation channel [PF08016.14, score=289.6]; PLAT/LH2 domain [PF01477.25, score=81.7]; Ion transport protein [PF00520.33, score=61.2]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=294, Expect=1e-81]} {Mouse: ENSMUSG00000052496, Pkdrej, polycystin (PKD) family receptor for egg jelly, [Score=266, Expect=1e-72]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=137, Expect=9e-33]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=156, Expect=3e-39]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=445, Expect=1e-132]} {RNA1509_2125} {RNA1310_81.1} {RNA815_193}

Mlig455_049403 {REF} {Length: 11572} {Pfam: Polycystin cation channel [PF08016.14, score=288.0]; PLAT/LH2 domain [PF01477.25, score=80.0]; Ion transport protein [PF00520.33, score=59.0]; PKD domain [PF18911.2, score=38.5]; PKD domain [PF00801.22, score=23.6]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=286, Expect=2e-76]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=271, Expect=7e-72]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=142, Expect=2e-33]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=150, Expect=1e-36]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=486, Expect=6e-138]} {RNA1509_2125} {RNA1310_81.1} {RNA815_193}
5. MligTC455_30137 264 5.5 Mlig455_038940

Neo: -

Age: logFC(26M/2M)=-0.387

 HEATR4 2.615 - - - 0.973 0.776 0.866 Mlig455_038940 {REF} {Length: 4881} {TRANSSPLICED} {Pfam: HEAT repeats [PF13646.8, score=79.1]; HEAT repeat [PF02985.24, score=44.0]; HEAT-like repeat [PF13513.8, score=24.2]} {Human: ENSG00000187105, HEATR4, HEAT repeat containing 4, [RH, Score=335, Expect=6e-97]} {Mouse: ENSMUSG00000090843, Heatr4, HEAT repeat containing 4, [RH, Score=328, Expect=5e-95]} {Smed: dd_Smed_v6_16127_0_1, dd_Smed_v6_16127_0_1, [RH, Score=460, Expect=5e-141]} {RNA1509_8516} {RNA1310_8186} {RNA815_1423.1}
6. MligTC455_44113 3565 74.27 Mlig455_032730, Mlig455_032753

Neo: -

Age: -

 CFAP97 2.545 - - - 0.762 0.951 0.832

Mlig455_032730 {REF} {Length: 2200} {Pfam: Hemingway/CFA97 [PF13879.8, score=36.8]} {Human: ENSG00000164323, CFAP97, cilia and flagella associated protein 97, [RH, Score=73.6, Expect=2e-13]} {Mouse: ENSMUSG00000031631, Cfap97, cilia and flagella associated protein 97, [RH, Score=73.6, Expect=1e-13]} {RNA1509_4299} {RNA1310_12911, RNA1509_4299} {RNA1509_4299, RNA815_4525.1}

Mlig455_032753 {REF} {Length: 2143} {Pfam: Hemingway/CFA97 [PF13879.8, score=36.8]} {Human: ENSG00000164323, CFAP97, cilia and flagella associated protein 97, [RH, Score=75.5, Expect=4e-14]} {Mouse: ENSMUSG00000031631, Cfap97, cilia and flagella associated protein 97, [RH, Score=75.5, Expect=3e-14]} {RNA1509_4299} {RNA1310_12911} {RNA815_4525.1}
7. MligTC455_41933 519 10.82 Mlig455_034108

Neo: -

Age: Down-Down-Up

 1.848 - - 0.968 0.880 - - Mlig455_034108 {REF} {Length: 2442} {RNA1509_22399} {RNA1310_1594.1} {RNA815_19978}
8. MligTC455_08176 295 6.14 Mlig455_003066

Neo: -

Age: Down-Up-Down

 ANK3 1.816 - - - 0.858 0.958 - Mlig455_003066 {REF} {Length: 1910} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=77.5]; Ankyrin repeat [PF00023.32, score=60.5]; Ankyrin repeats (many copies) [PF13637.8, score=47.3]; Ankyrin repeats (many copies) [PF13857.8, score=44.4]; Ankyrin repeat [PF13606.8, score=43.5]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=57.4, Expect=5e-08]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=53.1, Expect=7e-07]; ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=53.1, Expect=6e-07]; ENSMUSG00000047117, Ankdd1b, ankyrin repeat and death domain containing 1B, [Score=51.6, Expect=1e-06]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=50.8, Expect=3e-06]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=58.9, Expect=6e-09]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=53.5, Expect=3e-07]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=51.2, Expect=1e-06]} {RNA1509_10786} {RNA1310_15894, RNA1509_10786} {RNA1509_10786, RNA815_6009}
9. MligTC455_47783 422 8.78 Mlig455_031120

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.635

 1.797 - - 0.953 0.844 - - Mlig455_031120 {REF} {Length: 2684} {Pfam: Mab-21 protein [PF03281.16, score=59.6]} {Smed: dd_Smed_v6_43442_0_1, dd_Smed_v6_43442_0_1, [RH, Score=63.2, Expect=1e-10]} {RNA1509_15607} {RNA1310_11311} {RNA815_5452}
10. MligTC455_53683 2280 47.51 Mlig455_008125, Mlig455_008133

Neo: -

Age: -

 ERICH6 1.78 - - - 0.963 0.817 -

Mlig455_008125 {REF} {Length: 2384} {Pfam: FAM194 protein [PF14977.8, score=172.8]; Protein of unknown function (DUF429) [PF04250.15, score=20.3]} {Human: ENSG00000163645, ERICH6, glutamate rich 6, [Score=159, Expect=2e-41]} {Mouse: ENSMUSG00000070471, Erich6, glutamate rich 6, [Score=114, Expect=7e-26]} {Smed: dd_Smed_v6_11097_0_1, dd_Smed_v6_11097_0_1, [RH, Score=229, Expect=3e-66]} {RNA1509_13316} {RNA1310_9580.2} {RNA815_3023.1}

Mlig455_008133 {REF} {Length: 2411} {Pfam: FAM194 protein [PF14977.8, score=172.2]} {Human: ENSG00000163645, ERICH6, glutamate rich 6, [RH, Score=162, Expect=2e-42]} {Mouse: ENSMUSG00000070471, Erich6, glutamate rich 6, [Score=112, Expect=3e-25]} {Smed: dd_Smed_v6_11097_0_1, dd_Smed_v6_11097_0_1, [RH, Score=230, Expect=1e-66]} {RNA1509_15088} {RNA1310_8374} {RNA815_3023.1}
11. MligTC455_45856 1272 26.49 Mlig455_059174

Neo: -

Age: logFC(26M/2M)=-0.206

Region-enriched R2: 1.425/0.00231

 SEMA5A 1.778 - - - 0.826 0.952 - Mlig455_059174 {REF} {Length: 5250} {Pfam: Sema domain [PF01403.21, score=180.0]; Thrombospondin type 1 domain [PF00090.21, score=87.3]; Spondin-like TSP1 domain [PF19028.2, score=64.1]} {Human: ENSG00000112902, SEMA5A, semaphorin 5A, [RH, Score=346, Expect=1e-99]; ENSG00000082684, SEMA5B, semaphorin 5B, [RH, Score=342, Expect=1e-97]} {Mouse: ENSMUSG00000052133, Sema5b, sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B, [RH, Score=349, Expect=6e-101]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [RH, Score=315, Expect=4e-89]} {Celegans: WBGene00000082, adt-1, ADAMTS family; ADT-1, [Score=119, Expect=1e-26]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=159, Expect=5e-39]} {RNA1509_3299} {RNA1310_897, RNA1509_3299} {RNA1509_3299, RNA815_4837}
12. MligTC455_41880 1136 23.67 Mlig455_013517

Neo: -

Age: -

 1.774 - - 0.819 0.955 - - Mlig455_013517 {REF} {Length: 2631} {Smed: dd_Smed_v6_13043_0_1, dd_Smed_v6_13043_0_1, [RH, Score=299, Expect=4e-91]} {RNA1509_15478, RNA1509_18670} {RNA1310_7739.1, RNA1509_15478, RNA1509_18670} {RNA1509_15478, RNA1509_18670, RNA815_2588}
13. MligTC455_53774 2623 54.65 Mlig455_039561, Mlig455_051366

Neo: -

Age: logFC(26M/2M)=-0.322

Region-enriched R4: 1.262/0.01773

 SPATA6 1.771 - - - 0.965 0.806 -

Mlig455_039561 {REF} {Length: 2532} {TRANSSPLICED} {Pfam: Spermatogenesis-assoc protein 6 [PF14909.8, score=115.4]} {Human: ENSG00000132122, SPATA6, spermatogenesis associated 6, [RH, Score=105, Expect=4e-24]} {Mouse: ENSMUSG00000034401, Spata6, spermatogenesis associated 6, [RH, Score=99.0, Expect=4e-22]} {Smed: dd_Smed_v6_10543_0_1, dd_Smed_v6_10543_0_1, [Score=184, Expect=5e-55]} {RNA1509_28452, RNA1509_48064, RNA1509_8673} {RNA1310_20192, RNA1509_28452, RNA1509_48064} {RNA1509_28452, RNA1509_48064, RNA815_23278}

Mlig455_051366 {REF} {Length: 2585} {TRANSSPLICED} {Pfam: Spermatogenesis-assoc protein 6 [PF14909.8, score=114.8]} {Human: ENSG00000132122, SPATA6, spermatogenesis associated 6, [RH, Score=105, Expect=5e-24]} {Mouse: ENSMUSG00000034401, Spata6, spermatogenesis associated 6, [RH, Score=95.5, Expect=6e-21]} {Smed: dd_Smed_v6_10543_0_1, dd_Smed_v6_10543_0_1, [Score=184, Expect=6e-55]} {RNA1509_32010, RNA1509_32967, RNA1509_8673} {RNA1310_20192, RNA1509_32010, RNA1509_32967, RNA1509_8673} {RNA1509_32010, RNA1509_32967, RNA1509_8673, RNA815_17748}
14. MligTC455_18603 3778 78.7 Mlig455_050242

Neo: -

Age: -

 CCDC39 1.77 - - - 0.957 0.813 - Mlig455_050242 {REF} {Length: 3281} {Human: ENSG00000284862, CCDC39, coiled-coil domain containing 39, [RH, Score=698, Expect=0.0]} {Mouse: ENSMUSG00000027676, Ccdc39, coiled-coil domain containing 39, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0037276, CG17387, [RH, Score=157, Expect=4e-39]} {Smed: dd_Smed_v6_5955_0_1, dd_Smed_v6_5955_0_1, [RH, Score=779, Expect=0.0]} {RNA1509_738} {RNA1310_4021} {RNA815_1219}
15. MligTC455_35942 1134 23.63 Mlig455_048067

Neo: -

Age: logFC(26M/2M)=-0.435

 DCDC2C 1.753 - - - 0.953 - 0.800 Mlig455_048067 {REF} {Length: 3258} {Pfam: Doublecortin [PF03607.19, score=93.4]} {Human: ENSG00000214866, DCDC2C, doublecortin domain containing 2C, [RH, Score=100, Expect=7e-23]; ENSG00000146038, DCDC2, doublecortin domain containing 2, [RH, Score=100, Expect=3e-22]} {Mouse: ENSMUSG00000035910, Dcdc2a, doublecortin domain containing 2a, [RH, Score=105, Expect=2e-24]} {Celegans: WBGene00007374, C06C3.3, [RH, Score=52.4, Expect=4e-07]} {Smed: dd_Smed_v6_20159_0_1, dd_Smed_v6_20159_0_1, [RH, Score=187, Expect=9e-55]} {RNA1509_40680} {RNA1310_11042} {RNA815_6202}
16. MligTC455_38918 3484 72.59 Mlig455_016984

Neo: -

Age: -

 SPAG17 1.751 - - - 0.957 0.794 - Mlig455_016984 {REF} {Length: 7773} {Human: ENSG00000155761, SPAG17, sperm associated antigen 17, [Score=555, Expect=8e-162]} {Mouse: ENSMUSG00000027867, Spag17, sperm associated antigen 17, [Score=283, Expect=3e-76]} {Celegans: WBGene00015646, mlt-10, [RH, Score=177, Expect=1e-45]} {Smed: dd_Smed_v6_9301_0_1, dd_Smed_v6_9301_0_1, [Score=543, Expect=8e-159]} {RNA1509_1598} {RNA1310_263.1} {RNA815_1526.1}
17. MligTC455_20525 835 17.4 Mlig455_011504

Neo: -

Age: Up-Down-Down

 KMT2C 1.738 - - - - 0.964 0.774 Mlig455_011504 {REF} {Length: 14333} {TRANSSPLICED} {Pfam: PHD-finger [PF00628.31, score=101.1]; F/Y rich C-terminus [PF05965.16, score=82.0]; SET domain [PF00856.30, score=71.8]; F/Y-rich N-terminus [PF05964.16, score=63.3]; PHD-zinc-finger like domain [PF13832.8, score=56.8]; PHD-like zinc-binding domain [PF13771.8, score=49.6]; PHD-finger [PF13831.8, score=18.4]} {Human: ENSG00000055609, KMT2C, lysine methyltransferase 2C, [RH, Score=647, Expect=0.0]} {Mouse: ENSMUSG00000038056, Kmt2c, lysine (K)-specific methyltransferase 2C, [RH, Score=642, Expect=0.0]} {Dmel: FBgn0023518, trr, trithorax-related, [RH, Score=573, Expect=3e-165]} {Celegans: WBGene00011729, set-16, Histone-lysine N-methyltransferase, [RH, Score=227, Expect=8e-59]} {Smed: dd_Smed_v6_6838_0_1, dd_Smed_v6_6838_0_1, [Score=570, Expect=8e-172]} {RNA1509_12609} {RNA1310_2188} {RNA815_5011}
18. MligTC455_40318 4414 91.96 Mlig455_056386

Neo: -

Age: -

 LRRC23 1.737 - - 0.953 - - 0.784 Mlig455_056386 {REF} {Length: 1457} {TRANSSPLICED} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=98.6]; Leucine-rich repeat [PF14580.8, score=60.6]; Leucine rich repeat [PF13855.8, score=58.7]; Leucine Rich repeat [PF13516.8, score=38.0]; Leucine Rich Repeat [PF00560.35, score=23.0]} {Human: ENSG00000010626, LRRC23, leucine rich repeat containing 23, [RH, Score=288, Expect=4e-95]} {Mouse: ENSMUSG00000030125, Lrrc23, leucine rich repeat containing 23, [RH, Score=321, Expect=2e-108]} {Dmel: FBgn0085440, Lgr4, Leucine-rich repeat-containing G protein-coupled receptor 4, [Score=54.3, Expect=1e-07]} {Celegans: WBGene00015516, C06A8.6, [Score=102, Expect=1e-24]} {Smed: dd_Smed_v6_8299_0_1, dd_Smed_v6_8299_0_1, [RH, Score=286, Expect=9e-95]} {RNA1509_2421} {RNA1310_22202.1} {RNA815_8780.1}
19. MligTC455_16521 398 8.3 Mlig455_039107, Mlig455_042793

Neo: Irradiation

Age: logFC(26M/2M)=0.475

 AASS 1.696 - - - 0.741 - 0.955

Mlig455_039107 {REF} {Length: 3630} {Pfam: Saccharopine dehydrogenase C-terminal domain [PF16653.7, score=260.3]; Alanine dehydrogenase/PNT, N-terminal domain [PF05222.17, score=96.4]; Saccharopine dehydrogenase NADP binding domain [PF03435.20, score=66.7]; Alanine dehydrogenase/PNT, C-terminal domain [PF01262.23, score=34.3]} {Human: ENSG00000008311, AASS, aminoadipate-semialdehyde synthase, [RH, Score=952, Expect=0.0]} {Mouse: ENSMUSG00000029695, Aass, aminoadipate-semialdehyde synthase, [RH, Score=966, Expect=0.0]} {Dmel: FBgn0025687, LKRSDH, Lysine ketoglutarate reductase/saccharopine dehydrogenase, [RH, Score=1025, Expect=0.0]} {Celegans: WBGene00019819, R02D3.1, [RH, Score=953, Expect=0.0]} {Smed: dd_Smed_v6_2894_0_1, dd_Smed_v6_2894_0_1, [RH, Score=1134, Expect=0.0]} {RNA1509_22582} {RNA1310_3292.1} {RNA815_810.1}

Mlig455_042793 {REF} {Length: 3691} {Pfam: Saccharopine dehydrogenase C-terminal domain [PF16653.7, score=260.3]; Alanine dehydrogenase/PNT, N-terminal domain [PF05222.17, score=97.3]; Saccharopine dehydrogenase NADP binding domain [PF03435.20, score=66.8]; Alanine dehydrogenase/PNT, C-terminal domain [PF01262.23, score=34.3]} {Human: ENSG00000008311, AASS, aminoadipate-semialdehyde synthase, [RH, Score=952, Expect=0.0]} {Mouse: ENSMUSG00000029695, Aass, aminoadipate-semialdehyde synthase, [RH, Score=965, Expect=0.0]} {Dmel: FBgn0025687, LKRSDH, Lysine ketoglutarate reductase/saccharopine dehydrogenase, [RH, Score=1025, Expect=0.0]} {Celegans: WBGene00019819, R02D3.1, [RH, Score=954, Expect=0.0]} {Smed: dd_Smed_v6_2894_0_1, dd_Smed_v6_2894_0_1, [RH, Score=1134, Expect=0.0]} {RNA1509_22582} {RNA1310_3292.1, RNA1509_22582} {RNA1509_22582, RNA815_810.1}
20. MligTC455_12685 123 2.56 Mlig455_016759

Neo: -

Age: -

 CACNA1C 1.681 - - - 0.731 - 0.950 Mlig455_016759 {REF} {Length: 8335} {Pfam: Ion transport protein [PF00520.33, score=554.7]; Voltage gated calcium channel IQ domain [PF08763.13, score=101.9]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=91.1]; Polycystin cation channel [PF08016.14, score=22.2]} {Human: ENSG00000151067, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=1386, Expect=0.0]; ENSG00000285479, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=1386, Expect=0.0]; ENSG00000157388, CACNA1D, calcium voltage-gated channel subunit alpha1 D, [Score=1350, Expect=0.0]; ENSG00000081248, CACNA1S, calcium voltage-gated channel subunit alpha1 S, [Score=1324, Expect=0.0]} {Mouse: ENSMUSG00000051331, Cacna1c, calcium channel, voltage-dependent, L type, alpha 1C subunit, [Score=1393, Expect=0.0]; ENSMUSG00000015968, Cacna1d, calcium channel, voltage-dependent, L type, alpha 1D subunit, [Score=1343, Expect=0.0]} {Dmel: FBgn0001991, Ca-alpha1D, Ca[2+]-channel protein alpha[[1]] subunit D, [Score=1474, Expect=0.0]} {Celegans: WBGene00001187, egl-19, Voltage-dependent L-type calcium channel subunit alpha, [Score=1386, Expect=0.0]} {Smed: dd_Smed_v6_8899_0_23, dd_Smed_v6_8899_0_23, [Score=1537, Expect=0.0]} {RNA1509_7565} {RNA1310_601} {RNA815_3074}
21. MligTC455_26016 505 10.52 Mlig455_037068

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.264

 NR1I2 1.677 - - - 0.717 - 0.960 Mlig455_037068 {REF} {Length: 2140} {TRANSSPLICED} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=60.8]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=82.0, Expect=3e-16]; ENSG00000143257, NR1I3, nuclear receptor subfamily 1 group I member 3, [Score=79.7, Expect=1e-15]} {Mouse: ENSMUSG00000005677, Nr1i3, nuclear receptor subfamily 1, group I, member 3, [Score=80.1, Expect=5e-16]; ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=79.7, Expect=1e-15]} {Dmel: FBgn0261239, Hr39, Hormone receptor-like in 39, [Score=82.4, Expect=2e-16]} {Celegans: WBGene00003607, nhr-8, Nuclear hormone receptor family member nhr-8, [Score=87.8, Expect=2e-18]} {Smed: dd_Smed_v6_14067_0_2, dd_Smed_v6_14067_0_2, [RH, Score=90.9, Expect=3e-19]} {RNA1509_11585, RNA1509_27608} {RNA1310_7469, RNA1509_11585, RNA1509_27608} {RNA1509_11585, RNA1509_27608, RNA815_3672.2}
22. MligTC455_40424 474 9.88 Mlig455_029322

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.888

 CALM2 1.654 - - 0.953 - 0.701 - Mlig455_029322 {REF} {Length: 1020} {Pfam: EF-hand domain pair [PF13833.8, score=26.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=69.7, Expect=2e-14]; ENSG00000160014, CALM3, calmodulin 3, [Score=68.9, Expect=2e-14]; ENSG00000198668, CALM1, calmodulin 1, [Score=68.9, Expect=2e-14]; ENSG00000178363, CALML3, calmodulin like 3, [Score=68.2, Expect=3e-14]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=70.5, Expect=1e-14]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=68.9, Expect=1e-14]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=68.9, Expect=1e-14]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=67.4, Expect=3e-14]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=67.8, Expect=2e-14]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=67.8, Expect=2e-14]} {RNA1509_16604} {RNA1310_33121} {RNA815_17390}
23. MligTC455_49623 1254 26.13 Mlig455_005003, Mlig455_005044, Mlig455_005273

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.089/0.03938

 MAPRE1 0.989 - - 0.989 - - -

Mlig455_005003 {REF} {Length: 1466} {TRANSSPLICED} {Pfam: EB1-like C-terminal motif [PF03271.19, score=48.5]; Calponin homology (CH) domain [PF00307.33, score=45.4]} {Human: ENSG00000101367, MAPRE1, microtubule associated protein RP/EB family member 1, [RH, Score=256, Expect=1e-84]; ENSG00000084764, MAPRE3, microtubule associated protein RP/EB family member 3, [RH, Score=247, Expect=5e-81]} {Mouse: ENSMUSG00000027479, Mapre1, microtubule-associated protein, RP/EB family, member 1, [RH, Score=255, Expect=2e-84]; ENSMUSG00000029166, Mapre3, microtubule-associated protein, RP/EB family, member 3, [RH, Score=244, Expect=5e-80]} {Dmel: FBgn0027066, Eb1, [RH, Score=258, Expect=1e-85]} {Celegans: WBGene00013344, ebp-1, Microtubule End Binding Protein, [RH, Score=218, Expect=2e-69]} {Smed: dd_Smed_v6_1322_0_2, dd_Smed_v6_1322_0_2, [RH, Score=309, Expect=3e-105]} {RNA1509_15908} {RNA1310_22066} {RNA815_24384}

Mlig455_005044 {REF} {Length: 1464} {TRANSSPLICED} {Pfam: EB1-like C-terminal motif [PF03271.19, score=48.5]; Calponin homology (CH) domain [PF00307.33, score=45.4]} {Human: ENSG00000101367, MAPRE1, microtubule associated protein RP/EB family member 1, [RH, Score=256, Expect=1e-84]; ENSG00000084764, MAPRE3, microtubule associated protein RP/EB family member 3, [RH, Score=247, Expect=5e-81]} {Mouse: ENSMUSG00000027479, Mapre1, microtubule-associated protein, RP/EB family, member 1, [RH, Score=255, Expect=2e-84]; ENSMUSG00000029166, Mapre3, microtubule-associated protein, RP/EB family, member 3, [RH, Score=244, Expect=5e-80]} {Dmel: FBgn0027066, Eb1, [RH, Score=258, Expect=1e-85]} {Celegans: WBGene00013344, ebp-1, Microtubule End Binding Protein, [RH, Score=218, Expect=2e-69]} {Smed: dd_Smed_v6_1322_0_2, dd_Smed_v6_1322_0_2, [RH, Score=309, Expect=3e-105]} {RNA1509_15908} {RNA1310_22066} {RNA815_24384}

Mlig455_005273 {REF} {Length: 1471} {TRANSSPLICED} {Pfam: EB1-like C-terminal motif [PF03271.19, score=48.5]; Calponin homology (CH) domain [PF00307.33, score=45.4]} {Human: ENSG00000101367, MAPRE1, microtubule associated protein RP/EB family member 1, [RH, Score=256, Expect=1e-84]; ENSG00000084764, MAPRE3, microtubule associated protein RP/EB family member 3, [RH, Score=247, Expect=5e-81]} {Mouse: ENSMUSG00000027479, Mapre1, microtubule-associated protein, RP/EB family, member 1, [RH, Score=255, Expect=2e-84]; ENSMUSG00000029166, Mapre3, microtubule-associated protein, RP/EB family, member 3, [RH, Score=244, Expect=5e-80]} {Dmel: FBgn0027066, Eb1, [RH, Score=258, Expect=1e-85]} {Celegans: WBGene00013344, ebp-1, Microtubule End Binding Protein, [RH, Score=218, Expect=2e-69]} {Smed: dd_Smed_v6_1322_0_2, dd_Smed_v6_1322_0_2, [RH, Score=309, Expect=3e-105]} {RNA1509_15908} {RNA1310_22066} {RNA815_24384}
24. MligTC455_18570 1029 21.43 Mlig455_053836, Mlig455_068506

Neo: -

Age: -

 TDG 0.975 - - - - 0.975 -

Mlig455_053836 {REF} {Length: 3374} {TRANSSPLICED} {Pfam: Uracil DNA glycosylase superfamily [PF03167.21, score=61.7]} {Human: ENSG00000139372, TDG, thymine DNA glycosylase, [Score=200, Expect=6e-57]} {Mouse: ENSMUSG00000034674, Tdg, thymine DNA glycosylase, [Score=205, Expect=7e-59]} {Dmel: FBgn0026869, Thd1, [Score=249, Expect=3e-70]} {Smed: dd_Smed_v6_4053_0_1, dd_Smed_v6_4053_0_1, [RH, Score=342, Expect=2e-109]} {RNA1509_17434, RNA1509_31261} {RNA1310_4364, RNA1509_17434, RNA1509_31261} {RNA1509_17434, RNA1509_31261, RNA815_5870.1}

Mlig455_068506 {REF} {Length: 3371} {TRANSSPLICED} {Pfam: Uracil DNA glycosylase superfamily [PF03167.21, score=61.6]} {Human: ENSG00000139372, TDG, thymine DNA glycosylase, [Score=200, Expect=4e-57]} {Mouse: ENSMUSG00000034674, Tdg, thymine DNA glycosylase, [Score=205, Expect=6e-59]} {Dmel: FBgn0026869, Thd1, [Score=250, Expect=3e-70]} {Smed: dd_Smed_v6_4053_0_1, dd_Smed_v6_4053_0_1, [RH, Score=343, Expect=1e-109]} {RNA1509_17434, RNA1509_44433} {RNA1310_4364, RNA1509_44433} {RNA1509_44433, RNA815_5870.1}
25. MligTC455_25354 849 17.68 Mlig455_024735

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.352

Region-enriched R3: 1.182/0.04139

 AK5 0.968 - - - 0.968 - - Mlig455_024735 {REF} {Length: 2695} {TRANSSPLICED} {Pfam: Adenylate kinase [PF00406.24, score=66.5]; AAA domain [PF13207.8, score=57.7]; AAA domain [PF13238.8, score=27.5]; AAA domain [PF13245.8, score=22.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=20.0]; IQ calmodulin-binding motif [PF00612.29, score=19.0]} {Human: ENSG00000154027, AK5, adenylate kinase 5, [Score=157, Expect=8e-41]} {Mouse: ENSMUSG00000039058, Ak5, adenylate kinase 5, [Score=155, Expect=1e-40]} {Dmel: FBgn0032083, CG9541, [Score=84.0, Expect=9e-17]} {Celegans: WBGene00008746, F13E6.2, [Score=103, Expect=6e-23]} {Smed: dd_Smed_v6_5119_0_2, dd_Smed_v6_5119_0_2, [Score=217, Expect=1e-61]} {RNA1509_10957, RNA1509_17379, RNA1509_9162} {RNA1310_5460.2, RNA1509_10957, RNA1509_17379, RNA1509_9162} {RNA1509_10957, RNA1509_17379, RNA1509_9162, RNA815_2389}
26. MligTC455_19869 157 3.27 Mlig455_046439, Mlig455_046468

Neo: -

Age: -

 ZNF324 0.964 - - - - - 0.964

Mlig455_046439 {REF} {Length: 4053} {TRANSSPLICED} {Pfam: C2H2-type zinc finger [PF13894.8, score=58.9]; Zinc finger, C2H2 type [PF00096.28, score=53.6]; Zinc-finger double domain [PF13465.8, score=37.8]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=25.6]} {Human: ENSG00000083812, ZNF324, zinc finger protein 324, [Score=101, Expect=2e-21]} {Mouse: ENSMUSG00000004500, Zfp324, zinc finger protein 324, [Score=102, Expect=3e-22]} {Dmel: FBgn0033934, CG17385, [Score=82.8, Expect=6e-17]} {Celegans: WBGene00011066, ztf-15, Zinc finger putative Transcription Factor family, [RH, Score=67.0, Expect=4e-11]} {Smed: dd_Smed_v6_26394_0_1, dd_Smed_v6_26394_0_1, [Score=83.2, Expect=1e-17]} {RNA1509_14607} {RNA1310_8185} {RNA815_15544}

Mlig455_046468 {REF} {Length: 1996} {TRANSSPLICED} {Pfam: C2H2-type zinc finger [PF13894.8, score=69.8]; Zinc finger, C2H2 type [PF00096.28, score=62.0]; Zinc-finger double domain [PF13465.8, score=46.4]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=36.2]; Drought induced 19 protein (Di19), zinc-binding [PF05605.14, score=25.2]} {Human: ENSG00000083812, ZNF324, zinc finger protein 324, [Score=96.3, Expect=4e-22]; ENSG00000116809, ZBTB17, zinc finger and BTB domain containing 17, [Score=92.0, Expect=3e-20]; ENSG00000189180, ZNF33A, zinc finger protein 33A, [Score=92.0, Expect=3e-20]; ENSG00000249471, ZNF324B, zinc finger protein 324B, [Score=91.7, Expect=3e-20]; ENSG00000188321, ZNF559, zinc finger protein 559, [Score=91.7, Expect=3e-20]} {Mouse: ENSMUSG00000045519, Zfp560, zinc finger protein 560, [Score=97.4, Expect=3e-22]; ENSMUSG00000004500, Zfp324, zinc finger protein 324, [Score=96.3, Expect=5e-22]} {Dmel: FBgn0037617, nom, numerous disordered muscles, [Score=77.0, Expect=8e-16]} {Celegans: WBGene00011066, ztf-15, Zinc finger putative Transcription Factor family, [RH, Score=67.4, Expect=2e-12]} {Smed: dd_Smed_v6_14824_0_1, dd_Smed_v6_14824_0_1, [Score=73.6, Expect=6e-15]} {RNA1509_40166, RNA1509_56111} {RNA1310_14502, RNA1509_40166, RNA1509_56111} {RNA1509_40166, RNA1509_56111, RNA815_25948}
27. MligTC455_13877 78 1.63 Mlig455_008183

Neo: -

Age: logFC(26M/2M)=-0.935

 0.963 - - - - - 0.963 Mlig455_008183 {REF} {Length: 2362} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=22.0]} {Mouse: ENSMUSG00000036557, Stpg4, sperm tail PG rich repeat containing 4, [RH, Score=87.8, Expect=2e-20]} {RNA1509_25741, RNA1509_39148, RNA1509_40547, RNA1509_41492, RNA1509_49543, RNA1509_58011} {RNA1310_16702.1, RNA1509_25741, RNA1509_39148, RNA1509_40547, RNA1509_41492, RNA1509_49543, RNA1509_58011} {RNA1509_25741, RNA1509_39148, RNA1509_40547, RNA1509_41492, RNA1509_49543, RNA1509_58011, RNA815_7507.1}
28. MligTC455_49010 1913 39.85 Mlig455_020240

Neo: -

Age: logFC(26M/2M)=-0.260

 NEK7 0.963 - - - 0.963 - - Mlig455_020240 {REF} {Length: 3119} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=217.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=155.4]; Fungal protein kinase [PF17667.3, score=24.6]; Kinase-like [PF14531.8, score=24.1]; ABC1 atypical kinase-like domain [PF03109.18, score=19.3]} {Human: ENSG00000151414, NEK7, NIMA related kinase 7, [RH, Score=486, Expect=5e-174]; ENSG00000119408, NEK6, NIMA related kinase 6, [RH, Score=466, Expect=5e-166]} {Mouse: ENSMUSG00000026393, Nek7, NIMA (never in mitosis gene a)-related expressed kinase 7, [RH, Score=488, Expect=5e-175]; ENSMUSG00000026749, Nek6, NIMA (never in mitosis gene a)-related expressed kinase 6, [RH, Score=467, Expect=1e-166]} {Dmel: FBgn0029970, Nek2, [Score=186, Expect=7e-53]} {Celegans: WBGene00008956, nekl-3, Serine/threonine-protein kinase nekl-3, [RH, Score=433, Expect=9e-154]} {Smed: dd_Smed_v6_8347_0_2, dd_Smed_v6_8347_0_2, [RH, Score=448, Expect=1e-159]} {RNA1509_56262, RNA1509_56413, RNA1509_8536} {RNA1310_10308.1, RNA1509_56262, RNA1509_56413, RNA1509_8536} {RNA1509_56262, RNA1509_56413, RNA1509_8536, RNA815_10804.1}
29. MligTC455_26488 1000 20.84 Mlig455_006000

Neo: -

Age: -

 0.96 - - - - 0.960 - Mlig455_006000 {REF} {Length: 7297} {RNA1509_20686, RNA1509_23623, RNA1509_3283, RNA1509_38835, RNA1509_49135, RNA1509_49876} {RNA1310_2487, RNA1509_20686, RNA1509_23623, RNA1509_3283, RNA1509_38835, RNA1509_49135, RNA1509_49876} {RNA1509_20686, RNA1509_23623, RNA1509_3283, RNA1509_38835, RNA1509_49135, RNA1509_49876, RNA815_6150.1}
30. MligTC455_22439 124 2.58 Mlig455_002461

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.387

Region-enriched R2: 3.193/0.01798

 0.959 - - - - - 0.959 Mlig455_002461 {REF} {Length: 3179} {TRANSSPLICED} {Pfam: TIR domain [PF13676.8, score=78.5]; Protein of unknown function (DUF775) [PF05603.14, score=20.1]} {Smed: dd_Smed_v6_9242_0_1, dd_Smed_v6_9242_0_1, [Score=160, Expect=3e-41]} {RNA1509_15390, RNA1509_53623} {RNA1310_4628, RNA1509_15390, RNA1509_53623} {RNA1509_15390, RNA1509_53623, RNA815_1374}
31. MligTC455_15942 908 18.92 Mlig455_035020, Mlig455_053446

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.273

 NR1I2 0.954 - - - - 0.954 -

Mlig455_035020 {REF} {Length: 4424} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.8]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=87.4, Expect=1e-17]} {Mouse: ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=84.3, Expect=6e-17]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=81.3, Expect=6e-16]} {Dmel: FBgn0003720, tll, tailless, [Score=82.0, Expect=3e-16]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=99.4, Expect=2e-21]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=91.3, Expect=3e-19]} {RNA1509_8358} {RNA1310_9876} {RNA815_22592}

Mlig455_053446 {REF} {Length: 4372} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.7]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=87.0, Expect=2e-17]} {Mouse: ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=84.0, Expect=9e-17]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=80.9, Expect=8e-16]; ENSMUSG00000002393, Nr2f6, nuclear receptor subfamily 2, group F, member 6, [Score=80.1, Expect=1e-15]} {Dmel: FBgn0003720, tll, tailless, [Score=82.4, Expect=3e-16]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=99.8, Expect=1e-21]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=91.3, Expect=2e-19]} {RNA1509_8358} {RNA1310_9876} {RNA815_22592}
32. MligTC455_42516 171 3.55 Mlig455_054052

Neo: -

Age: -

 PLXDC2 0.954 - - - 0.954 - - Mlig455_054052 {REF} {Length: 3561} {Human: ENSG00000120594, PLXDC2, plexin domain containing 2, [RH, Score=174, Expect=4e-48]; ENSG00000161381, PLXDC1, plexin domain containing 1, [RH, Score=173, Expect=4e-48]} {Mouse: ENSMUSG00000026748, Plxdc2, plexin domain containing 2, [RH, Score=183, Expect=8e-52]; ENSMUSG00000017417, Plxdc1, plexin domain containing 1, [RH, Score=177, Expect=2e-49]} {Dmel: FBgn0028331, l(1)G0289, lethal (1) G0289, [RH, Score=161, Expect=3e-43]} {Celegans: WBGene00007982, pxd-1, PleXin Domain containing, [RH, Score=162, Expect=3e-44]} {Smed: dd_Smed_v6_68203_0_1, dd_Smed_v6_68203_0_1, [RH, Score=95.1, Expect=4e-23]} {RNA1509_4680} {RNA1310_14519.1} {RNA815_6406.1}
33. MligTC455_36497 307 6.4 Mlig455_027376

Neo: -

Age: -

 ANKRD28 0.952 - - 0.952 - - - Mlig455_027376 {REF} {Length: 4258} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=387.1]; Ankyrin repeats (many copies) [PF13637.8, score=338.0]; Ankyrin repeat [PF00023.32, score=278.6]; Ankyrin repeats (many copies) [PF13857.8, score=266.3]; Ankyrin repeat [PF13606.8, score=249.8]} {Human: ENSG00000206560, ANKRD28, ankyrin repeat domain 28, [Score=572, Expect=0.0]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=550, Expect=2e-177]} {Mouse: ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=573, Expect=0.0]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=231, Expect=5e-61]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=211, Expect=3e-55]} {Smed: dd_Smed_v6_7952_0_1, dd_Smed_v6_7952_0_1, [Score=392, Expect=6e-118]} {RNA1509_34578} {RNA1310_5778.1, RNA1509_34578} {RNA1509_34578, RNA815_24866}

Refine r cutoff to:    Show

Berezikov Lab - 2020-2021 © ERIBA