Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_44452 | 288 | 6.01 | Mlig455_042439 | Neo: - |
HDHD2 | Mlig455_042439 {REF} {Length: 1234} {TRANSSPLICED} {Pfam: HAD-hyrolase-like [PF13242.8, score=58.4]; Haloacid dehalogenase-like hydrolase [PF13344.8, score=45.8]; Haloacid dehalogenase-like hydrolase [PF13419.8, score=19.4]} {Human: ENSG00000167220, HDHD2, haloacid dehalogenase like hydrolase domain containing 2, [Score=196, Expect=9e-62]} {Mouse: ENSMUSG00000025421, Hdhd2, haloacid dehalogenase-like hydrolase domain containing 2, [RH, Score=195, Expect=2e-61]} {Dmel: FBgn0032032, CG17294, [RH, Score=189, Expect=2e-59]} {Celegans: WBGene00019522, K08B12.3, [RH, Score=173, Expect=3e-53]} {Smed: dd_Smed_v6_8083_0_2, dd_Smed_v6_8083_0_2, [Score=111, Expect=3e-29]} {RNA1509_58503} {RNA1310_40641, RNA1509_58503} {RNA1509_58503, RNA815_47576} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 1.41 | 2.996 | 0.29255 | 0.94460 | |
RegionR2 | -0.052 | 2.996 | 0.93209 | 1.00000 | |
RegionR3 | -0.574 | 2.996 | 0.25042 | 0.79426 | |
RegionR4 | 0.367 | 2.996 | 0.49102 | 0.81783 | |
RegionR5 | -0.674 | 2.996 | 0.13763 | 0.38062 | |
RegionR6 | -1.131 | 2.996 | 0.04669 | 0.40399 | |
RegionR7 | 0.976 | 2.996 | 0.11345 | 0.63855 | |
RegionR8 | -0.322 | 2.996 | 0.75129 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -7.044 | 2.996 | 0.10080 | 0.81804 | |
RegenerationR2 | -0.162 | 2.996 | 0.71447 | 0.96157 | |
RegenerationR3 | 0.88 | 2.996 | 0.09205 | 0.48918 | |
RegenerationR4 | 0.478 | 2.996 | 0.33261 | 0.76632 | |
RegenerationR5 | 0.839 | 2.996 | 0.07398 | 0.42590 | |
RegenerationR6 | 1.244 | 2.996 | 0.03548 | 0.23603 | |
RegenerationBL | 1.255 | 2.996 | 0.04021 | 0.22763 | |
RegenerationTP | 0.408 | 2.996 | 0.57646 | 0.94760 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_44452 | 288 | 6.01 | Mlig455_042439 | Neo: - |
HDHD2 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_042439 {REF} {Length: 1234} {TRANSSPLICED} {Pfam: HAD-hyrolase-like [PF13242.8, score=58.4]; Haloacid dehalogenase-like hydrolase [PF13344.8, score=45.8]; Haloacid dehalogenase-like hydrolase [PF13419.8, score=19.4]} {Human: ENSG00000167220, HDHD2, haloacid dehalogenase like hydrolase domain containing 2, [Score=196, Expect=9e-62]} {Mouse: ENSMUSG00000025421, Hdhd2, haloacid dehalogenase-like hydrolase domain containing 2, [RH, Score=195, Expect=2e-61]} {Dmel: FBgn0032032, CG17294, [RH, Score=189, Expect=2e-59]} {Celegans: WBGene00019522, K08B12.3, [RH, Score=173, Expect=3e-53]} {Smed: dd_Smed_v6_8083_0_2, dd_Smed_v6_8083_0_2, [Score=111, Expect=3e-29]} {RNA1509_58503} {RNA1310_40641, RNA1509_58503} {RNA1509_58503, RNA815_47576} |
2. | MligTC455_37724 | 781 | 16.28 | Mlig455_065465 | Neo: - |
ROR1 | 1.808 | 0.854 | - | 0.954 | - | - | - | Mlig455_065465 {REF} {Length: 4059} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=240.2]; Protein kinase domain [PF00069.27, score=101.6]; Immunoglobulin I-set domain [PF07679.18, score=45.2]; Immunoglobulin domain [PF13927.8, score=42.8]; Fz domain [PF01392.24, score=34.0]; Immunoglobulin domain [PF13895.8, score=32.3]; Immunoglobulin domain [PF00047.27, score=24.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=398, Expect=5e-123]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=402, Expect=6e-125]} {Dmel: FBgn0010407, Ror, [Score=276, Expect=1e-80]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=220, Expect=1e-59]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=398, Expect=3e-124]} {RNA1509_15729, RNA1509_49184} {RNA1310_2781.1, RNA1509_15729, RNA1509_49184} {RNA1509_15729, RNA1509_49184, RNA815_11745} |
3. | MligTC455_43824 | 958 | 19.97 | Mlig455_044228, Mlig455_044247 | Neo: - Age: - |
SF3B2 | 1.793 | - | - | 0.954 | - | - | 0.839 | Mlig455_044228 {REF} {Length: 2484} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF382) [PF04037.15, score=190.9]; PSP [PF04046.18, score=66.7]} {Human: ENSG00000087365, SF3B2, splicing factor 3b subunit 2, [RH, Score=478, Expect=7e-159]} {Mouse: ENSMUSG00000024853, Sf3b2, splicing factor 3b, subunit 2, [RH, Score=476, Expect=5e-158]} {Dmel: FBgn0031493, Sf3b2, Splicing factor 3b subunit 2, [RH, Score=464, Expect=2e-155]} {Celegans: WBGene00021004, sftb-2, Splicing Factor ThreeB (3b) Subunit homolog, [RH, Score=410, Expect=2e-136]} {Smed: dd_Smed_v6_2932_0_1, dd_Smed_v6_2932_0_1, [RH, Score=439, Expect=2e-148]} {RNA1509_3603} {RNA1310_8711} {RNA815_178.1} Mlig455_044247 {REF} {Length: 2482} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF382) [PF04037.15, score=190.9]; PSP [PF04046.18, score=66.6]} {Human: ENSG00000087365, SF3B2, splicing factor 3b subunit 2, [RH, Score=478, Expect=5e-159]} {Mouse: ENSMUSG00000024853, Sf3b2, splicing factor 3b, subunit 2, [RH, Score=475, Expect=6e-158]} {Dmel: FBgn0031493, Sf3b2, Splicing factor 3b subunit 2, [RH, Score=464, Expect=2e-155]} {Celegans: WBGene00021004, sftb-2, Splicing Factor ThreeB (3b) Subunit homolog, [RH, Score=410, Expect=2e-136]} {Smed: dd_Smed_v6_2932_0_1, dd_Smed_v6_2932_0_1, [RH, Score=438, Expect=4e-148]} {RNA1509_3603} {RNA1310_8711, RNA1509_3603} {RNA1509_3603, RNA815_178.1} |
4. | MligTC455_22920 | 196 | 4.08 | Mlig455_039387 | Neo: - Age: - |
TRPC4 | 1.786 | - | - | 0.956 | - | - | 0.830 | Mlig455_039387 {REF} {Length: 2289} {Human: ENSG00000133107, TRPC4, transient receptor potential cation channel subfamily C member 4, [Score=62.4, Expect=2e-10]} {Mouse: ENSMUSG00000027748, Trpc4, transient receptor potential cation channel, subfamily C, member 4, [Score=63.5, Expect=6e-11]} {Dmel: FBgn0032593, Trpgamma, Transient receptor potential cation channel gamma, [Score=98.6, Expect=6e-23]} {Smed: dd_Smed_v6_20495_0_1, dd_Smed_v6_20495_0_1, [Score=155, Expect=1e-42]} {RNA1509_26602} {RNA1310_3579} {RNA815_924} |
5. | MligTC455_27923 | 318 | 6.64 | Mlig455_037735 | Neo: - Age: - |
1.769 | - | - | 0.970 | - | - | 0.799 | Mlig455_037735 {REF} {Length: 2740} {Pfam: Noggin [PF05806.14, score=33.9]} {Smed: dd_Smed_v6_7999_0_1, dd_Smed_v6_7999_0_1, [Score=77.4, Expect=1e-16]} {RNA1509_58515} {RNA1310_28925, RNA1509_58515} {RNA1509_58515, RNA815_419.1} | |
6. | MligTC455_12252 | 153 | 3.18 | Mlig455_007987 | Neo: - Age: - |
1.732 | - | - | 0.950 | - | - | 0.782 | Mlig455_007987 {REF} {Length: 516} {NoTransDecoderORF} {RNA1509_52260} {RNA1310_51099} | |
7. | MligTC455_44386 | 437 | 9.1 | Mlig455_012895 | Neo: - Age: logFC(26M/2M)=-0.237 |
ITK | 1.705 | - | - | 0.953 | - | - | 0.752 | Mlig455_012895 {REF} {Length: 6093} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=267.7]; Protein kinase domain [PF00069.27, score=135.1]; SH2 domain [PF00017.26, score=82.8]; PH domain [PF00169.31, score=51.1]; BTK motif [PF00779.21, score=37.2]; SH3 domain [PF00018.30, score=32.1]; Variant SH3 domain [PF14604.8, score=28.1]; Variant SH3 domain [PF07653.19, score=19.5]} {Human: ENSG00000113263, ITK, IL2 inducible T cell kinase, [RH, Score=452, Expect=6e-151]; ENSG00000010671, BTK, Bruton tyrosine kinase, [RH, Score=450, Expect=2e-149]; ENSG00000135605, TEC, tec protein tyrosine kinase, [RH, Score=439, Expect=3e-145]} {Mouse: ENSMUSG00000031264, Btk, Bruton agammaglobulinemia tyrosine kinase, [RH, Score=450, Expect=2e-149]; ENSMUSG00000029217, Tec, tec protein tyrosine kinase, [RH, Score=439, Expect=1e-145]; ENSMUSG00000020395, Itk, IL2 inducible T cell kinase, [RH, Score=439, Expect=7e-146]} {Dmel: FBgn0003502, Btk29A, Btk family kinase at 29A, [RH, Score=439, Expect=7e-144]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=314, Expect=2e-99]} {Smed: dd_Smed_v6_4818_0_1, dd_Smed_v6_4818_0_1, [RH, Score=663, Expect=0.0]} {RNA1509_14118, RNA1509_20637, RNA1509_33645, RNA1509_41278, RNA1509_43358} {RNA1310_11225, RNA1509_14118, RNA1509_20637, RNA1509_33645, RNA1509_41278, RNA1509_43358} {RNA1509_14118, RNA1509_20637, RNA1509_33645, RNA1509_41278, RNA1509_43358, RNA815_1375.1} |
8. | MligTC455_43877 | 2496 | 52.01 | Mlig455_014455 | Neo: - |
SELENOT | 1.685 | - | - | - | - | 0.960 | 0.725 | Mlig455_014455 {REF} {Length: 1680} {TRANSSPLICED} {Pfam: Rdx family [PF10262.11, score=36.8]} {Human: ENSG00000198843, SELENOT, selenoprotein T, [Score=90.1, Expect=8e-24]} {Mouse: ENSMUSG00000075700, Selenot, selenoprotein T, [Score=90.1, Expect=7e-24]} {Dmel: FBgn0031670, CG3887, [Score=94.0, Expect=2e-25]} {Celegans: WBGene00007955, selt-1.1, Putative selT-like protein C35C5.3, [Score=83.2, Expect=4e-21]} {Smed: dd_Smed_v6_969_0_1, dd_Smed_v6_969_0_1, [RH, Score=104, Expect=2e-30]} {RNA1509_4381, RNA1509_7204} {RNA1310_55836.1, RNA1509_7204} {RNA1509_7204, RNA815_9707.1} |
9. | MligTC455_53775 | 449 | 9.35 | Mlig455_012089 | Neo: Int S/G2/M Age: - |
1.685 | - | - | 0.952 | - | - | 0.733 | Mlig455_012089 {REF} {Length: 2012} {NoTransDecoderORF} {RNA1509_35827} {RNA1310_45584} {RNA815_12875} | |
10. | MligTC455_25264 | 1074 | 22.38 | Mlig455_009112 | Neo: - Age: logFC(26M/2M)=-0.304 Region-enriched R3: 1.128/0.04871 |
VPS37B | 1.683 | - | - | - | 0.728 | 0.955 | - | Mlig455_009112 {REF} {Length: 1615} {TRANSSPLICED} {Pfam: Modifier of rudimentary (Mod(r)) protein [PF07200.15, score=82.5]} {Human: ENSG00000139722, VPS37B, VPS37B, ESCRT-I subunit, [RH, Score=79.3, Expect=5e-17]} {Mouse: ENSMUSG00000048832, Vps37c, vacuolar protein sorting 37C, [RH, Score=67.4, Expect=1e-12]; ENSMUSG00000066278, Vps37b, vacuolar protein sorting 37B, [RH, Score=66.2, Expect=2e-12]} {Dmel: FBgn0037299, Vps37B, Vacuolar protein sorting 37B, [Score=55.5, Expect=4e-09]} {RNA1509_4762} {RNA1310_1499.1} {RNA815_9957} |
11. | MligTC455_45215 | 353 | 7.36 | Mlig455_018358 | Neo: - |
SRC | 0.966 | - | - | 0.966 | - | - | - | Mlig455_018358 {REF} {Length: 4483} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=315.0]; Protein kinase domain [PF00069.27, score=159.7]; SH2 domain [PF00017.26, score=78.3]; SH3 domain [PF00018.30, score=38.7]; Variant SH3 domain [PF14604.8, score=33.8]; Haspin like kinase domain [PF12330.10, score=23.3]; ABC1 atypical kinase-like domain [PF03109.18, score=20.6]; Variant SH3 domain [PF07653.19, score=19.3]} {Human: ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [RH, Score=474, Expect=3e-162]} {Mouse: ENSMUSG00000027646, Src, Rous sarcoma oncogene, [RH, Score=473, Expect=8e-162]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=479, Expect=1e-164]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [RH, Score=464, Expect=9e-159]} {Smed: dd_Smed_v6_6272_0_1, dd_Smed_v6_6272_0_1, [RH, Score=537, Expect=0.0]} {RNA1509_8558} {RNA1310_4765} {RNA815_99} |
12. | MligTC455_29698 | 153 | 3.19 | Mlig455_038104 | Neo: - Age: logFC(26M/2M)=-0.330 |
ANKRD17 | 0.962 | - | - | 0.962 | - | - | - | Mlig455_038104 {REF} {Length: 7732} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=444.0]; Ankyrin repeats (many copies) [PF13637.8, score=254.7]; Ankyrin repeats (many copies) [PF13857.8, score=146.5]; Ankyrin repeat [PF13606.8, score=141.2]; Transcription factor BRX N-terminal domain [PF13713.8, score=129.7]; Ankyrin repeat [PF00023.32, score=103.7]; Domain of unknown function (DUF4476) [PF14771.8, score=54.5]; Mab-21 protein [PF03281.16, score=36.7]; HEAT repeats [PF13646.8, score=20.0]; Protein of unknown function (DUF3307) [PF11750.10, score=18.9]} {Human: ENSG00000132466, ANKRD17, ankyrin repeat domain 17, [Score=167, Expect=1e-40]} {Mouse: ENSMUSG00000055204, Ankrd17, ankyrin repeat domain 17, [Score=166, Expect=2e-40]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=114, Expect=7e-25]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=120, Expect=8e-27]} {Smed: dd_Smed_v6_5303_0_2, dd_Smed_v6_5303_0_2, [Score=160, Expect=2e-39]} {RNA1509_27730, RNA1509_55013} {RNA1310_21755.1, RNA1509_55013} {RNA1509_55013, RNA815_2426.1} |
13. | MligTC455_27642 | 279 | 5.82 | Mlig455_006426 | Neo: - Age: - Region-enriched R4: 1.960/0.00696 |
NOTCH1 | 0.959 | - | - | 0.959 | - | - | - | Mlig455_006426 {REF} {Length: 4913} {TRANSSPLICED} {Pfam: EGF-like domain [PF00008.29, score=151.4]; Human growth factor-like EGF [PF12661.9, score=74.2]} {Human: ENSG00000148400, NOTCH1, notch 1, [Score=290, Expect=1e-81]} {Mouse: ENSMUSG00000026923, Notch1, notch 1, [Score=295, Expect=3e-83]} {Dmel: FBgn0259685, crb, crumbs, [Score=256, Expect=2e-70]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=214, Expect=8e-57]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=220, Expect=5e-59]} {RNA1509_33949, RNA1509_39530, RNA1509_42581, RNA1509_43325} {RNA1310_10126, RNA1509_39530, RNA1509_42581, RNA1509_43325} {RNA1509_39530, RNA1509_42581, RNA1509_43325, RNA815_693.1} |
14. | MligTC455_53400 | 345 | 7.18 | Mlig455_011902 | Neo: - |
0.957 | - | - | 0.957 | - | - | - | Mlig455_011902 {REF} {Length: 1541} {RNA1509_4217} {RNA1310_16120} {RNA815_27428} | |
15. | MligTC455_47196 | 826 | 17.21 | Mlig455_032049 | Neo: - Age: logFC(26M/2M)=-0.232 |
0.955 | - | - | 0.955 | - | - | - | Mlig455_032049 {REF} {Length: 2910} {TRANSSPLICED} {Pfam: AN1-like Zinc finger [PF01428.18, score=22.3]} {RNA1509_32678, RNA1509_50490, RNA1509_59424} {RNA1310_5881, RNA1509_32678, RNA1509_50490, RNA1509_59424} {RNA1509_32678, RNA1509_50490, RNA1509_59424, RNA815_13594} | |
16. | MligTC455_49780 | 780 | 16.24 | Mlig455_053889 | Neo: - Age: Down-Up-Down |
TAX1BP3 | 0.955 | - | - | 0.955 | - | - | - | Mlig455_053889 {REF} {Length: 1679} {TRANSSPLICED} {Pfam: PDZ domain [PF00595.26, score=47.9]; PDZ domain [PF17820.3, score=42.3]; PDZ domain [PF13180.8, score=29.5]} {Human: ENSG00000213977, TAX1BP3, Tax1 binding protein 3, [RH, Score=69.7, Expect=1e-15]} {Mouse: ENSMUSG00000040158, Tax1bp3, Tax1 (human T cell leukemia virus type I) binding protein 3, [RH, Score=69.7, Expect=9e-16]} {Dmel: FBgn0035148, CG3402, [RH, Score=88.2, Expect=4e-23]} {Celegans: WBGene00016678, C45G9.7, [RH, Score=92.0, Expect=1e-24]} {Smed: dd_Smed_v6_7732_0_1, dd_Smed_v6_7732_0_1, [Score=47.8, Expect=4e-07]} {RNA1509_46994, RNA1509_56445} {RNA1310_49427.1, RNA1509_56445} {RNA1509_56445, RNA815_26268.2} |
17. | MligTC455_44381 | 50 | 1.04 | Mlig455_034187 | Neo: - Age: - |
0.954 | - | - | 0.954 | - | - | - | Mlig455_034187 {REF} {Length: 1133} {Pfam: WSC domain [PF01822.21, score=41.3]} {RNA1310_44307} {RNA815_33128} | |
18. | MligTC455_25521 | 83 | 1.73 | Mlig455_003486, Mlig455_015573 | Neo: - Age: Up-Down-Down |
0.95 | - | - | 0.950 | - | - | - | Mlig455_003486 {REF} {Length: 1884} {RNA1310_20102} {RNA815_31096} Mlig455_015573 {REF} {Length: 1889} {RNA1310_20102} {RNA815_31096} |
|
19. | MligTC455_26413 | 528 | 11.01 | Mlig455_070891 | Neo: - |
EPS8 | 0.95 | - | - | 0.950 | - | - | - | Mlig455_070891 {REF} {Length: 3874} {TRANSSPLICED} {Pfam: SH3 domain [PF00018.30, score=22.5]; Variant SH3 domain [PF07653.19, score=20.3]} {Human: ENSG00000151491, EPS8, epidermal growth factor receptor pathway substrate 8, [RH, Score=145, Expect=8e-37]} {Mouse: ENSMUSG00000015766, Eps8, epidermal growth factor receptor pathway substrate 8, [Score=154, Expect=3e-40]} {Dmel: FBgn0029095, aru, arouser, [RH, Score=140, Expect=4e-35]} {Celegans: WBGene00001330, eps-8, EPS (Human endocytosis) related; Epidermal growth factor receptor pathway substrate 8 splice variant A, [Score=204, Expect=4e-57]} {Smed: dd_Smed_v6_8993_0_1, dd_Smed_v6_8993_0_1, [RH, Score=74.3, Expect=6e-14]} {RNA1509_27030, RNA1509_45513, RNA1509_55389, RNA1509_59954, RNA1509_7172} {RNA1310_7150.1, RNA1509_27030, RNA1509_45513, RNA1509_55389, RNA1509_59954, RNA1509_7172} {RNA1509_27030, RNA1509_45513, RNA1509_55389, RNA1509_59954, RNA1509_7172, RNA815_2475.1} |