Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_44698 | 264 | 5.49 | Mlig455_048394 | Neo: - Age: - Region-enriched R3: 3.473/0.00001 Regeneration-downregulated R3: -2.124 Regeneration-depleted R3: -2.124 |
SLC10A2 | Mlig455_048394 {REF} {Length: 2470} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=57.4]} {Human: ENSG00000125255, SLC10A2, solute carrier family 10 member 2, [Score=89.0, Expect=5e-20]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=93.2, Expect=9e-22]; ENSMUSG00000029321, Slc10a6, solute carrier family 10 (sodium/bile acid cotransporter family), member 6, [Score=93.2, Expect=1e-21]} {Dmel: FBgn0030638, CG11655, [Score=82.4, Expect=8e-18]} {Celegans: WBGene00044650, Y71G10AR.4, [Score=126, Expect=2e-33]} {Smed: dd_Smed_v6_11330_0_1, dd_Smed_v6_11330_0_1, [Score=199, Expect=3e-61]} {RNA1509_40196} {RNA1310_16142.1} {RNA815_16613} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -4.637 | 3.184 | 0.99958 | 1.00000 | |
RegionR2 | -1.236 | 3.184 | 0.94763 | 1.00000 | |
RegionR3 | 3.473 | 3.184 | 0.00000 | 0.00001 | |
RegionR4 | 3.001 | 3.184 | 0.00009 | 0.00141 | |
RegionR5 | 2.605 | 3.184 | 0.00016 | 0.00241 | |
RegionR6 | 1.714 | 3.184 | 0.06794 | 0.48675 | |
RegionR7 | -0.535 | 3.184 | 0.87427 | 1.00000 | |
RegionR8 | -4.385 | 3.184 | 1.00000 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 4.173 | 3.184 | 0.47452 | 1.00000 | |
RegenerationR2 | -0.572 | 3.184 | 0.56079 | 0.89885 | |
RegenerationR3 | -2.124 | 3.184 | 0.00000 | 0.00021 | Specific for R3: -2.124 |
RegenerationR4 | -1.139 | 3.184 | 0.00815 | 0.13390 | |
RegenerationR5 | -1.074 | 3.184 | 0.00363 | 0.10762 | |
RegenerationR6 | 0.438 | 3.184 | 0.33725 | 0.68363 | |
RegenerationBL | 2.01 | 3.184 | 0.14196 | 0.44920 | |
RegenerationTP | 2.384 | 3.184 | 0.25110 | 0.69848 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_44698 | 264 | 5.49 | Mlig455_048394 | Neo: - Age: - Region-enriched R3: 3.473/0.00001 Regeneration-downregulated R3: -2.124 Regeneration-depleted R3: -2.124 |
SLC10A2 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_048394 {REF} {Length: 2470} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=57.4]} {Human: ENSG00000125255, SLC10A2, solute carrier family 10 member 2, [Score=89.0, Expect=5e-20]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=93.2, Expect=9e-22]; ENSMUSG00000029321, Slc10a6, solute carrier family 10 (sodium/bile acid cotransporter family), member 6, [Score=93.2, Expect=1e-21]} {Dmel: FBgn0030638, CG11655, [Score=82.4, Expect=8e-18]} {Celegans: WBGene00044650, Y71G10AR.4, [Score=126, Expect=2e-33]} {Smed: dd_Smed_v6_11330_0_1, dd_Smed_v6_11330_0_1, [Score=199, Expect=3e-61]} {RNA1509_40196} {RNA1310_16142.1} {RNA815_16613} |
2. | MligTC455_18868 | 1328 | 27.67 | Mlig455_067483 | Neo: - Age: - Region-enriched R3: 1.928/0.00492 |
4.136 | 0.791 | 0.952 | - | 0.853 | 0.740 | 0.800 | Mlig455_067483 {REF} {Length: 405} {RNA1509_5037} {RNA1310_19379} {RNA815_6182.1} | |
3. | MligTC455_18869 | 1346 | 28.04 | Mlig455_067491 | Neo: - Age: - Region-enriched R3: 1.933/0.00397 |
4.125 | 0.789 | 0.950 | - | 0.850 | 0.738 | 0.798 | Mlig455_067491 {REF} {Length: 2320} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=72.5]; GDP-mannose 4,6 dehydratase [PF16363.7, score=51.3]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=46.4]; Male sterility protein [PF07993.14, score=42.2]; NAD(P)H-binding [PF13460.8, score=39.3]; Polysaccharide biosynthesis protein [PF02719.17, score=30.0]; KR domain [PF08659.12, score=29.5]; NmrA-like family [PF05368.15, score=28.0]; short chain dehydrogenase [PF00106.27, score=19.3]} {Celegans: WBGene00017429, F13D11.4, [RH, Score=213, Expect=4e-66]} {RNA1509_20033, RNA1509_5037} {RNA1310_19379, RNA1509_20033, RNA1509_5037} {RNA1509_20033, RNA1509_5037, RNA815_6182.1} | |
4. | MligTC455_43496 | 1498 | 31.21 | Mlig455_029024 | Neo: Int S/G2/M Age: - Region-enriched R4: 1.717/0.01619 |
AGMO | 2.663 | - | - | - | 0.908 | 0.794 | 0.961 | Mlig455_029024 {REF} {Length: 1741} {Pfam: Fatty acid hydroxylase superfamily [PF04116.15, score=95.8]} {Human: ENSG00000187546, AGMO, alkylglycerol monooxygenase, [Score=324, Expect=3e-106]} {Mouse: ENSMUSG00000050103, Agmo, alkylglycerol monooxygenase, [Score=325, Expect=4e-107]} {Celegans: WBGene00007210, agmo-1, Alkylglycerol monooxygenase, [Score=248, Expect=2e-76]} {Smed: dd_Smed_v6_3673_0_1, dd_Smed_v6_3673_0_1, [Score=311, Expect=1e-102]} {RNA1509_15122} {RNA1310_18131, RNA1509_15122} {RNA1509_15122, RNA815_6945} |
5. | MligTC455_41954 | 117 | 2.44 | Mlig455_030295 | Neo: - Age: Up-Down-Up |
1.79 | - | - | - | 0.965 | - | 0.825 | Mlig455_030295 {REF} {Length: 548} {NoTransDecoderORF} {RNA1509_38678} {RNA1310_19204} {RNA815_26429} | |
6. | MligTC455_42343 | 1304 | 27.17 | Mlig455_063169 | Neo: Germline Age: - Region-enriched R4: 1.890/0.00018 |
SCP2 | 1.776 | - | - | - | 0.815 | - | 0.961 | Mlig455_063169 {REF} {Length: 1895} {TRANSSPLICED} {Pfam: SCP-2 sterol transfer family [PF02036.19, score=88.8]; MDMPI C-terminal domain [PF07398.13, score=21.2]; Sterol carrier protein domain [PF13530.8, score=19.3]; Alkyl sulfatase C-terminal [PF14864.8, score=19.2]} {Human: ENSG00000116171, SCP2, sterol carrier protein 2, [Score=104, Expect=3e-29]} {Mouse: ENSMUSG00000028603, Scp2, sterol carrier protein 2, liver, [Score=105, Expect=6e-27]} {Dmel: FBgn0015808, ScpX, Sterol carrier protein X-related thiolase, [Score=108, Expect=4e-28]} {Smed: dd_Smed_v6_1403_0_1, dd_Smed_v6_1403_0_1, [RH, Score=130, Expect=8e-40]} {RNA1509_20094, RNA1509_53670} {RNA1310_43575.1, RNA1509_20094, RNA1509_53670} {RNA1509_20094, RNA1509_53670, RNA815_23129} |
7. | MligTC455_15582 | 934 | 19.46 | Mlig455_007361, Mlig455_066677 | Neo: - Age: - |
1.67 | - | - | - | - | 0.968 | 0.702 | Mlig455_007361 {REF} {Length: 1553} {RNA1509_53067} {RNA1310_37733} {RNA815_26178} Mlig455_066677 {REF} {Length: 1285} {RNA1509_53067} {RNA1310_37733, RNA1509_53067} {RNA1509_53067, RNA815_26178} |
|
8. | MligTC455_21445 | 13458 | 280.38 | Mlig455_038347 | Neo: Neoblast Age: - |
RAN | 1.669 | - | - | - | 0.712 | 0.957 | - | Mlig455_038347 {REF} {Length: 1519} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=172.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=110.3]; ADP-ribosylation factor family [PF00025.23, score=44.0]; 50S ribosome-binding GTPase [PF01926.25, score=23.9]; RNA helicase [PF00910.24, score=22.7]; RsgA GTPase [PF03193.18, score=19.3]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.2]; G-protein alpha subunit [PF00503.22, score=18.2]} {Human: ENSG00000132341, RAN, RAN, member RAS oncogene family, [RH, Score=381, Expect=5e-136]} {Mouse: ENSMUSG00000029430, Ran, RAN, member RAS oncogene family, [RH, Score=381, Expect=4e-136]; ENSMUSG00000028287, 1700009N14Rik, RIKEN cDNA 1700009N14 gene, [RH, Score=373, Expect=4e-133]; ENSMUSG00000083649, Rasl2-9, RAS-like, family 2, locus 9, [RH, Score=362, Expect=1e-128]} {Dmel: FBgn0020255, Ran, [RH, Score=366, Expect=3e-130]} {Celegans: WBGene00004302, ran-1, GTP-binding nuclear protein ran-1, [RH, Score=369, Expect=2e-131]} {Smed: dd_Smed_v6_330_0_1, dd_Smed_v6_330_0_1, [RH, Score=380, Expect=4e-136]} {RNA1509_15492, RNA1509_845} {RNA1310_21472.1, RNA1509_15492, RNA1509_845} {RNA1509_15492, RNA1509_845, RNA815_8699} |
9. | MligTC455_40311 | 795 | 16.57 | Mlig455_005646 | Neo: - Age: logFC(26M/2M)=-1.077 Region-enriched R4: 2.244/0.00079 |
CYP2J2 | 0.966 | - | - | - | - | - | 0.966 | Mlig455_005646 {REF} {Length: 2326} {Pfam: Cytochrome P450 [PF00067.24, score=345.0]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=303, Expect=4e-97]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=280, Expect=2e-88]; ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=1e-88]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=278, Expect=3e-87]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=276, Expect=8e-87]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=3e-85]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=271, Expect=1e-84]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=1e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=270, Expect=2e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=2e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=6e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=223, Expect=5e-66]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=249, Expect=1e-76]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=260, Expect=8e-81]} {RNA1509_32472} {RNA1310_10280} {RNA815_4805} |
10. | MligTC455_21941 | 57 | 1.2 | Mlig455_005337, Mlig455_008287, Mlig455_042435, Mlig455_042486 | Neo: - Age: Down-Up-Down |
0.964 | - | - | 0.964 | - | - | - | Mlig455_005337 {REF} {Length: 1085} {RNA1310_43853} {RNA815_33228} Mlig455_008287 {REF} {Length: 716} {Pfam: Phage integrase family [PF00589.24, score=27.0]} {RNA1310_43853} {RNA815_33228} Mlig455_042435 {REF} {Length: 1075} {Pfam: Phage integrase family [PF00589.24, score=24.5]} {RNA1310_28668} {RNA815_33228} Mlig455_042486 {REF} {Length: 1073} {Pfam: Phage integrase family [PF00589.24, score=24.5]} {RNA1509_29315} {RNA1310_28668} {RNA815_33228} |
|
11. | MligTC455_53529 | 2550 | 53.12 | Mlig455_050344, Mlig455_050358 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.066 Region-enriched R3: 2.938/0.00005 |
0.96 | - | 0.960 | - | - | - | - | Mlig455_050344 {REF} {Length: 1567} {TRANSSPLICED} {Pfam: Universal stress protein family [PF00582.28, score=66.6]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=90.9, Expect=3e-24]} {RNA1509_7232} {RNA1310_40756} {RNA815_18182.1} Mlig455_050358 {REF} {Length: 1565} {TRANSSPLICED} {Pfam: Universal stress protein family [PF00582.28, score=99.8]} {Smed: dd_Smed_v6_985_0_1, dd_Smed_v6_985_0_1, [RH, Score=118, Expect=1e-34]} {RNA1509_7232} {RNA1310_40756} {RNA815_18182.2} |
|
12. | MligTC455_45434 | 932 | 19.42 | Mlig455_035818 | Neo: - Age: - Regeneration-enriched R5: 2.662 |
CNDP2 | 0.956 | - | - | - | - | - | 0.956 | Mlig455_035818 {REF} {Length: 2188} {TRANSSPLICED} {Pfam: Peptidase family M20/M25/M40 [PF01546.30, score=124.7]; Peptidase dimerisation domain [PF07687.16, score=59.0]} {Human: ENSG00000133313, CNDP2, carnosine dipeptidase 2, [RH, Score=636, Expect=0.0]} {Mouse: ENSMUSG00000024644, Cndp2, CNDP dipeptidase 2 (metallopeptidase M20 family), [RH, Score=640, Expect=0.0]} {Dmel: FBgn0259979, CG17337, [RH, Score=584, Expect=0.0]} {Celegans: WBGene00022176, Y71H2AM.11, [RH, Score=542, Expect=0.0]} {Smed: dd_Smed_v6_38736_0_1, dd_Smed_v6_38736_0_1, [RH, Score=122, Expect=1e-32]} {RNA1509_17346, RNA1509_2276, RNA1509_7153} {RNA1310_11591, RNA1509_17346, RNA1509_2276, RNA1509_7153} {RNA1509_17346, RNA1509_2276, RNA1509_7153, RNA815_4031.1} |
13. | MligTC455_21807 | 799 | 16.65 | Mlig455_007459 | Neo: Neoblast, stringent Age: - Region-enriched R4: 2.408/0.00022 |
CNFN | 0.954 | - | - | - | - | 0.954 | - | Mlig455_007459 {REF} {Length: 4701} {Pfam: PLAC8 family [PF04749.19, score=53.4]} {Human: ENSG00000105427, CNFN, cornifelin, [Score=53.5, Expect=2e-08]} {Mouse: ENSMUSG00000063651, Cnfn, cornifelin, [Score=56.6, Expect=1e-09]} {Smed: dd_Smed_v6_865_0_1, dd_Smed_v6_865_0_1, [Score=86.3, Expect=4e-20]} {RNA1509_19934} {RNA1310_30308.1} {RNA815_18628.1} |
14. | MligTC455_30308 | 112 | 2.34 | Mlig455_064892 | Neo: - Age: Up-Down-Down, logFC(26M/2M)=-0.615 Region-enriched R3: 4.002/0.00001 |
ANKRD28 | 0.953 | - | - | 0.953 | - | - | - | Mlig455_064892 {REF} {Length: 5718} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=153.9]; Ankyrin repeats (many copies) [PF13637.8, score=105.2]; Ankyrin repeats (many copies) [PF13857.8, score=66.3]; Ankyrin repeat [PF13606.8, score=56.3]; Ankyrin repeat [PF00023.32, score=52.9]; Ankyrin ubiquitin-binding domain [PF18418.3, score=28.5]} {Human: ENSG00000206560, ANKRD28, ankyrin repeat domain 28, [Score=64.3, Expect=5e-10]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=63.9, Expect=7e-10]; ENSG00000139645, ANKRD52, ankyrin repeat domain 52, [Score=62.4, Expect=2e-09]} {Mouse: ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=77.4, Expect=4e-14]} {Dmel: FBgn0029137, Patsas, [Score=52.8, Expect=9e-07]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=72.4, Expect=7e-13]} {Smed: dd_Smed_v6_21003_0_1, dd_Smed_v6_21003_0_1, [Score=49.7, Expect=6e-06]} {RNA1509_40476, RNA1509_49250, RNA1509_51982} {RNA1310_19601.2, RNA1509_40476, RNA1509_51982} {RNA1509_40476, RNA1509_51982, RNA815_2803.1} |
15. | MligTC455_08784 | 74 | 1.55 | Mlig455_018978 | Neo: - Age: - Region-enriched R4: 3.721/0.00921 |
0.95 | - | - | - | - | - | 0.950 | Mlig455_018978 {REF} {Length: 741} {RNA1310_46406} | |
16. | MligTC455_22802 | 375 | 7.81 | Mlig455_057869 | Neo: Neoblast, stringent Age: logFC(26M/2M)=0.211 Region-enriched R5: 2.321/0.00758 |
MCM7 | 0.95 | - | - | - | - | 0.950 | - | Mlig455_057869 {REF} {Length: 3104} {Pfam: MCM P-loop domain [PF00493.25, score=325.4]; MCM OB domain [PF17207.5, score=119.7]; MCM AAA-lid domain [PF17855.3, score=73.6]; MCM N-terminal domain [PF14551.8, score=58.8]; Magnesium chelatase, subunit ChlI [PF01078.23, score=25.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=21.2]} {Human: ENSG00000166508, MCM7, minichromosome maintenance complex component 7, [RH, Score=868, Expect=0.0]} {Mouse: ENSMUSG00000029730, Mcm7, minichromosome maintenance complex component 7, [RH, Score=866, Expect=0.0]} {Dmel: FBgn0020633, Mcm7, Minichromosome maintenance 7, [RH, Score=829, Expect=0.0]} {Celegans: WBGene00003159, mcm-7, DNA helicase, [RH, Score=639, Expect=0.0]} {Smed: dd_Smed_v6_4712_0_1, dd_Smed_v6_4712_0_1, [RH, Score=724, Expect=0.0]} {RNA1509_14333} {RNA1310_4893.2} {RNA815_1611} |