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Results for MligTC455_44809

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_44809 88 1.83 Mlig455_035938

Neo: -

Age: -

Mlig455_035938 {REF} {Length: 1369} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}

Cumulative graph for MligTC455_44809

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.328 1.712 0.99979 1.00000
RegionR2 5.046 1.712 0.02040 0.15506
RegionR3 0.473 1.712 0.48039 0.98275
RegionR4 0.23 1.712 0.69595 0.98615
RegionR5 0.204 1.712 0.54062 0.90362
RegionR6 -2.434 1.712 0.99981 1.00000
RegionR7 -2.014 1.712 0.99985 1.00000
RegionR8 -1.833 1.712 0.99984 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 5.21 1.712 0.46367 1.00000
RegenerationR2 -0.356 1.712 0.58392 0.90846
RegenerationR3 -1.167 1.712 0.41941 0.81444
RegenerationR4 -0.554 1.712 0.92969 1.00000
RegenerationR5 -2.494 1.712 0.07392 0.42590
RegenerationR6 2.386 1.712 0.20964 0.55274
RegenerationBL -0.276 1.712 0.99999 1.00000
RegenerationTP 0.598 1.712 0.70608 1.00000


Genes with expression patterns similar to MligTC455_44809

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_44809 88 1.83 Mlig455_035938

Neo: -

Age: -

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_035938 {REF} {Length: 1369} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}
2. MligTC455_44810 226 4.72 Mlig455_013293, Mlig455_035940, Mlig455_058406, Mlig455_058409

Neo: -

Age: -

Region-specific R2: 6.204

Region-enriched R2: 5.509/0.00501

4.783 0.799 - 0.991 0.995 0.998 1.000

Mlig455_013293 {REF} {Length: 1362} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=56.6, Expect=2e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_035940 {REF} {Length: 1652} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_058406 {REF} {Length: 991} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=4e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_058409 {REF} {Length: 1311} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}
3. MligTC455_18614 342 7.13 Mlig455_021102

Neo: -

Age: logFC(26M/2M)=1.052

Region-specific R2: 6.427

Region-enriched R2: 5.869/0.00003

4.67 0.881 - 0.941 0.984 0.983 0.881 Mlig455_021102 {REF} {Length: 1417} {RNA1509_43477} {RNA1310_26398} {RNA815_11119}
4. MligTC455_53682 393 8.18 Mlig455_064952, Mlig455_066834

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.926

Region-enriched R2: 4.442/0.00896

4.55 0.886 - 0.919 0.920 0.855 0.970

Mlig455_064952 {REF} {Length: 1573} {Pfam: PAN domain [PF00024.28, score=20.0]} {RNA1310_33258} {RNA815_17150}

Mlig455_066834 {REF} {Length: 1573} {Pfam: PAN domain [PF00024.28, score=20.0]} {RNA1310_33258} {RNA815_17150}
5. MligTC455_35259 2265 47.19 Mlig455_040978

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.606

Region-enriched R2: 1.588/0.00387

ADGRL2 4.45 0.911 - 0.842 0.955 0.753 0.989 Mlig455_040978 {REF} {Length: 10808} {TRANSSPLICED} {Pfam: PDZ domain [PF00595.26, score=86.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=76.2]; PDZ domain [PF17820.3, score=67.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=52.3]; PDZ domain [PF13180.8, score=36.4]; ZU5 domain [PF00791.22, score=30.8]; Guanylate kinase [PF00625.23, score=22.4]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [RH, Score=174, Expect=1e-42]} {Mouse: ENSMUSG00000034917, Tjp3, tight junction protein 3, [RH, Score=172, Expect=9e-43]} {Dmel: FBgn0262614, pyd, polychaetoid, [RH, Score=232, Expect=8e-61]} {Celegans: WBGene00013683, zoo-1, ZO-1 (Zonula Occludens tight junctional protein) Ortholog, [Score=174, Expect=4e-43]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [RH, Score=833, Expect=0.0]} {RNA1509_17602, RNA1509_52679, RNA1509_58629} {RNA1310_236.2, RNA1509_17602, RNA1509_58629} {RNA1509_17602, RNA1509_58629, RNA815_77.1}
6. MligTC455_47712 80 1.66 Mlig455_044833

Neo: -

Age: -

4.45 0.917 - 0.976 0.754 0.812 0.991 Mlig455_044833 {REF} {Length: 564} {RNA1509_55855} {RNA1310_87612} {RNA815_50831}
7. MligTC455_42994 1521 31.7 Mlig455_035840

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.356

Region-enriched R2: 1.854/0.00052

4.45 0.843 - 0.957 0.910 0.760 0.980 Mlig455_035840 {REF} {Length: 1436} {RNA1509_29485, RNA1509_42231} {RNA1310_26640, RNA1509_29485, RNA1509_42231} {RNA1509_29485, RNA1509_42231, RNA815_37260}
8. MligTC455_53239 733 15.27 Mlig455_025537

Neo: -

Age: -

Region-specific R2: 4.434

Region-enriched R2: 3.108/0.00000

4.401 0.776 - 0.881 0.848 0.932 0.964 Mlig455_025537 {REF} {Length: 964} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=28.0]} {Dmel: FBgn0051221, CG31221, [RH, Score=70.9, Expect=5e-15]} {Celegans: WBGene00010290, F58H1.7, [Score=63.9, Expect=8e-13]} {Smed: dd_Smed_v6_5576_0_1, dd_Smed_v6_5576_0_1, [RH, Score=168, Expect=2e-53]} {RNA1509_58542} {RNA1310_40950} {RNA815_19778.1}
9. MligTC455_46394 8810 183.54 Mlig455_054818, Mlig455_054826

Neo: -

Age: -

Region-specific R2: 1.771

Region-enriched R2: 1.255/0.00038

PKD2 4.392 0.870 - 0.857 0.982 0.708 0.975

Mlig455_054818 {REF} {Length: 2992} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=747, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=380, Expect=6e-120]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [Score=733, Expect=0.0]} {RNA1509_1615} {RNA1310_21296.2, RNA1509_1615} {RNA1509_1615, RNA815_3158.1}

Mlig455_054826 {REF} {Length: 3118} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.4]; EF hand [PF00036.34, score=32.6]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=754, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=751, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=2e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=1e-122]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
10. MligTC455_36985 363 7.57 Mlig455_046905

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.516

SCNN1A 4.391 0.818 - 0.721 0.964 0.894 0.994 Mlig455_046905 {REF} {Length: 2490} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=171.1]} {Human: ENSG00000111319, SCNN1A, sodium channel epithelial 1 alpha subunit, [Score=68.6, Expect=2e-11]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=67.0, Expect=3e-11]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=58.2, Expect=1e-08]} {Smed: dd_Smed_v6_29341_0_1, dd_Smed_v6_29341_0_1, [Score=100, Expect=2e-22]} {RNA1509_33610} {RNA1310_13314.1, RNA1509_33610} {RNA1509_33610, RNA815_4277}
11. MligTC455_42579 1841 38.34 Mlig455_061617

Neo: -

Age: -

Region-enriched R7: 1.560/0.01513

Regeneration-downregulated BL: -2.445

Regeneration-depleted BL: -2.445

CAV2 4.38 0.763 - 0.877 0.991 0.777 0.972 Mlig455_061617 {REF} {Length: 4295} {Pfam: Caveolin [PF01146.19, score=121.3]} {Human: ENSG00000105971, CAV2, caveolin 2, [Score=87.4, Expect=2e-22]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [Score=90.1, Expect=1e-23]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=73.2, Expect=1e-16]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [Score=144, Expect=2e-45]} {RNA1509_24227} {RNA1310_41576, RNA1509_24227} {RNA1509_24227, RNA815_20166}
12. MligTC455_36014 1671 34.81 Mlig455_004210

Neo: -

Age: Up-Up-Down

Region-enriched R2: 2.167/0.00118

PLA2G3 4.355 0.797 0.904 0.911 0.765 - 0.978 Mlig455_004210 {REF} {Length: 1631} {Pfam: Phospholipase A2 [PF05826.14, score=106.6]} {Human: ENSG00000100078, PLA2G3, phospholipase A2 group III, [RH, Score=97.4, Expect=6e-23]} {Mouse: ENSMUSG00000034579, Pla2g3, phospholipase A2, group III, [RH, Score=99.4, Expect=5e-24]} {Dmel: FBgn0030013, GIIIspla2, Phospholipase A2 group III, [RH, Score=97.8, Expect=5e-25]} {Smed: dd_Smed_v6_3851_0_2, dd_Smed_v6_3851_0_2, [RH, Score=103, Expect=4e-27]} {RNA1509_17589, RNA1509_26075, RNA1509_28230, RNA1509_8881} {RNA1310_22647, RNA1509_17589, RNA1509_26075, RNA1509_28230, RNA1509_8881} {RNA1509_17589, RNA1509_26075, RNA1509_28230, RNA1509_8881, RNA815_9445}
13. MligTC455_45666 652 13.58 Mlig455_013011, Mlig455_013040

Neo: -

Age: Up-Down-Up

Region-specific R2: 4.509

Region-enriched R2: 3.140/0.01108

4.311 0.769 0.953 0.892 0.714 - 0.983

Mlig455_013011 {REF} {Length: 1193} {RNA1509_13068} {RNA1310_46610} {RNA815_23273}

Mlig455_013040 {REF} {Length: 923} {RNA1509_13068} {RNA1310_46610, RNA1509_13068} {RNA1509_13068, RNA815_23273}
14. MligTC455_14831 280 5.83 Mlig455_067864

Neo: -

Age: Up-Down-Up

Region-enriched R2: 3.261/0.00352

SSUH2 4.244 0.906 - 0.910 0.757 0.705 0.966 Mlig455_067864 {REF} {Length: 1575} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=184, Expect=6e-54]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=148, Expect=7e-41]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=118, Expect=1e-29]} {RNA1509_46058} {RNA1310_5028.1} {RNA815_5650}
15. MligTC455_19339 1746 36.37 Mlig455_055775

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.338

Region-specific R2: 3.573

Region-enriched R2: 2.166/0.00065

4.239 0.709 - 0.818 0.869 0.970 0.873 Mlig455_055775 {REF} {Length: 1701} {TRANSSPLICED} {RNA1509_28058, RNA1509_53885} {RNA1310_50737, RNA1509_28058, RNA1509_53885} {RNA1509_28058, RNA1509_53885, RNA815_26880}
16. MligTC455_27938 137 2.85 Mlig455_033961

Neo: -

Age: -

3.865 - - 0.898 0.995 0.984 0.988 Mlig455_033961 {REF} {Length: 3296} {Pfam: Glycine rich protein [PF12810.9, score=20.4]} {RNA1310_28736.1} {RNA815_45605}
17. MligTC455_40610 165 3.43 Mlig455_064484

Neo: -

Age: -

Region-enriched R2: 5.617/0.00105

3.835 - - 0.989 0.953 0.896 0.997 Mlig455_064484 {REF} {Length: 2931} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=24.9]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [Score=154, Expect=2e-40]} {RNA1509_26568} {RNA1310_9342.1, RNA1509_26568} {RNA1509_26568, RNA815_7018}
18. MligTC455_35258 2779 57.89 Mlig455_040964

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.469

Region-enriched R2: 1.501/0.00133

3.766 0.901 - 0.949 0.929 - 0.987 Mlig455_040964 {REF} {Length: 8259} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=543, Expect=9e-160]} {RNA1509_16633, RNA1509_52679} {RNA1310_236.2, RNA1509_16633} {RNA1509_16633, RNA815_77.1}
19. MligTC455_41540 190 3.96 Mlig455_060056

Neo: -

Age: -

Region-enriched R2: 6.605/0.00196

GLUL 3.766 0.812 - 0.963 0.995 - 0.996 Mlig455_060056 {REF} {Length: 1355} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=57.3]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=47.5]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=511, Expect=1e-180]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=511, Expect=0.0]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=511, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=515, Expect=0.0]} {Smed: dd_Smed_v6_896_0_1, dd_Smed_v6_896_0_1, [RH, Score=545, Expect=0.0]} {RNA1509_47000} {RNA1310_22329.2} {RNA815_4116.6}
20. MligTC455_53681 335 6.99 Mlig455_064921

Neo: -

Age: -

Region-enriched R2: 6.469/0.00000

3.763 0.899 - 0.966 0.994 0.904 - Mlig455_064921 {REF} {Length: 1504} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1310_33258} {RNA815_17150}
21. MligTC455_48561 779 16.24 Mlig455_034702, Mlig455_034755

Neo: -

Age: -

FABP4 3.758 - - 0.953 0.972 0.913 0.920

Mlig455_034702 {REF} {Length: 723} {Human: ENSG00000170323, FABP4, fatty acid binding protein 4, [Score=43.9, Expect=8e-06]} {RNA1509_39777} {RNA1310_54956} {RNA815_27929.1}

Mlig455_034755 {REF} {Length: 924} {Human: ENSG00000170323, FABP4, fatty acid binding protein 4, [Score=43.9, Expect=8e-06]} {RNA1509_39777} {RNA1310_54956, RNA1509_39777} {RNA1509_39777, RNA815_27929.1}
22. MligTC455_49926 50 1.04 Mlig455_062317

Neo: -

Age: -

VSX1 3.756 - - 0.859 0.947 0.962 0.988 Mlig455_062317 {REF} {Length: 1610} {Pfam: Homeodomain [PF00046.31, score=79.8]} {Human: ENSG00000100987, VSX1, visual system homeobox 1, [RH, Score=202, Expect=4e-61]; ENSG00000119614, VSX2, visual system homeobox 2, [RH, Score=201, Expect=1e-60]} {Mouse: ENSMUSG00000021239, Vsx2, visual system homeobox 2, [RH, Score=201, Expect=8e-61]; ENSMUSG00000033080, Vsx1, visual system homeobox 1, [RH, Score=198, Expect=2e-59]} {Dmel: FBgn0263512, Vsx2, Visual system homeobox 2, [RH, Score=208, Expect=6e-61]} {Celegans: WBGene00000435, ceh-10, Homeobox protein ceh-10, [RH, Score=210, Expect=1e-64]} {Smed: dd_Smed_v6_19286_0_1, dd_Smed_v6_19286_0_1, [RH, Score=212, Expect=1e-65]} {RNA1310_39008} {RNA815_19602}
23. MligTC455_45495 988 20.58 Mlig455_010003

Neo: -

Age: logFC(26M/2M)=0.384

Region-enriched R2: 2.517/0.00003

CAV2 3.753 0.882 - 0.908 0.972 - 0.991 Mlig455_010003 {REF} {Length: 748} {Pfam: Caveolin [PF01146.19, score=125.0]} {Human: ENSG00000105971, CAV2, caveolin 2, [Score=85.5, Expect=3e-21]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [Score=89.4, Expect=7e-23]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=79.0, Expect=2e-18]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=153, Expect=1e-48]} {RNA1509_20287} {RNA1310_50581.1} {RNA815_31873}
24. MligTC455_18682 1190 24.79 Mlig455_037756

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.877

Region-enriched R2: 4.609/0.00000

3.751 0.876 - 0.948 0.930 - 0.997 Mlig455_037756 {REF} {Length: 1188} {RNA1509_25826} {RNA1310_42757} {RNA815_23874}
25. MligTC455_46605 388 8.08 Mlig455_032055

Neo: -

Age: -

Region-specific R2: 4.152

3.74 0.914 - 0.884 0.977 - 0.965 Mlig455_032055 {REF} {Length: 1416} {RNA1310_44339} {RNA815_20624}
26. MligTC455_19266 1038 21.61 Mlig455_004528, Mlig455_028530

Neo: -

Age: -

Region-specific R2: 2.706

Region-enriched R2: 1.766/0.00005

NCALD 3.704 0.890 - 0.938 0.967 - 0.909

Mlig455_004528 {REF} {Length: 3958} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_14564} {RNA1310_18405, RNA1509_14564} {RNA1509_14564, RNA815_10180.1}

Mlig455_028530 {REF} {Length: 3453} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_13995, RNA1509_14564, RNA1509_30926} {RNA1310_18405, RNA1509_13995, RNA1509_30926} {RNA1509_13995, RNA1509_30926, RNA815_10180.1}
27. MligTC455_18683 419 8.74 Mlig455_069928

Neo: -

Age: -

Region-specific R2: 6.066

Region-enriched R2: 4.921/0.00217

3.7 0.804 - 0.948 0.950 - 0.998 Mlig455_069928 {REF} {Length: 845} {RNA1509_25826} {RNA1310_42757} {RNA815_23874}
28. MligTC455_43173 392 8.16 Mlig455_037383

Neo: -

Age: Up-Down-Down

Regeneration-downregulated TP: -5.031

Regeneration-depleted TP: -5.031

C2orf16 3.693 0.935 - 0.934 0.834 - 0.990 Mlig455_037383 {REF} {Length: 2450} {Pfam: Cornifin (SPRR) family [PF02389.17, score=23.4]} {Human: ENSG00000221843, C2orf16, chromosome 2 open reading frame 16, [Score=80.1, Expect=7e-15]} {RNA1509_52401} {RNA1310_14622.1} {RNA815_17994}
29. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

3.668 0.711 - 0.995 0.966 - 0.996 Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
30. MligTC455_41028 108 2.26 Mlig455_033278

Neo: -

Age: -

3.662 - - 0.841 0.976 0.859 0.986 Mlig455_033278 {REF} {Length: 1134} {Pfam: PAN domain [PF00024.28, score=19.4]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=9e-14]} {RNA1310_31986} {RNA815_17816.2}
31. MligTC455_19114 79 1.64 Mlig455_045107

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.813

3.66 - - 0.866 0.910 0.891 0.993 Mlig455_045107 {REF} {Length: 1513} {Pfam: F5/8 type C domain [PF00754.27, score=20.0]} {RNA1509_57504} {RNA1310_27303.2} {RNA815_32964}
32. MligTC455_38682 102 2.12 Mlig455_039641

Neo: -

Age: -

Region-enriched R2: 6.138/0.02363

SLC18A3 3.658 0.719 - 0.981 0.992 - 0.966 Mlig455_039641 {REF} {Length: 3925} {Pfam: Major Facilitator Superfamily [PF07690.18, score=147.1]; Sugar (and other) transporter [PF00083.26, score=29.0]; LacY proton/sugar symporter [PF01306.21, score=20.2]} {Human: ENSG00000187714, SLC18A3, solute carrier family 18 member A3, [RH, Score=469, Expect=9e-161]} {Mouse: ENSMUSG00000100241, Slc18a3, solute carrier family 18 (vesicular monoamine), member 3, [RH, Score=469, Expect=1e-160]} {Dmel: FBgn0270928, VAChT, Vesicular acetylcholine transporter, [RH, Score=513, Expect=2e-177]} {Celegans: WBGene00006756, unc-17, Vesicular acetylcholine transporter unc-17, [RH, Score=486, Expect=2e-167]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [RH, Score=563, Expect=0.0]} {RNA1310_28397} {RNA815_32284.1}
33. MligTC455_36842 340 7.08 Mlig455_056552

Neo: -

Age: -

Region-enriched R2: 2.409/0.00668

SYT11 3.657 - 0.981 0.917 0.858 - 0.901 Mlig455_056552 {REF} {Length: 3533} {Pfam: C2 domain [PF00168.32, score=153.6]} {Human: ENSG00000132718, SYT11, synaptotagmin 11, [RH, Score=310, Expect=7e-102]} {Mouse: ENSMUSG00000068923, Syt11, synaptotagmin XI, [RH, Score=309, Expect=8e-102]} {Dmel: FBgn0028400, Syt4, Synaptotagmin 4, [RH, Score=355, Expect=3e-119]} {Celegans: WBGene00004924, snt-4, SyNapTotagmin, [RH, Score=237, Expect=1e-74]} {Smed: dd_Smed_v6_7243_0_1, dd_Smed_v6_7243_0_1, [Score=372, Expect=4e-127]} {RNA1509_16916, RNA1509_47189} {RNA1310_9964.1, RNA1509_16916, RNA1509_47189} {RNA1509_16916, RNA1509_47189, RNA815_17687}
34. MligTC455_35701 66 1.37 Mlig455_010067, Mlig455_063254, Mlig455_063279

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.716/0.02468

3.656 - - 0.947 0.974 0.747 0.988

Mlig455_010067 {REF} {Length: 2624} {Pfam: Polycystin cation channel [PF08016.14, score=46.7]} {RNA1310_62521}

Mlig455_063254 {REF} {Length: 2738} {Pfam: Polycystin cation channel [PF08016.14, score=43.3]; Lipopolysaccharide assembly protein A domain [PF06305.13, score=18.4]} {RNA1509_7418} {RNA1310_62521} {RNA815_3659}

Mlig455_063279 {REF} {Length: 2677} {Pfam: Polycystin cation channel [PF08016.14, score=46.0]} {RNA1310_62521}
35. MligTC455_39988 83 1.73 Mlig455_062081

Neo: -

Age: -

3.646 0.720 - 0.983 0.945 - 0.998 Mlig455_062081 {REF} {Length: 447} {NoTransDecoderORF} {RNA1509_50426} {RNA1310_88257} {RNA815_17173.4}
36. MligTC455_34499 65 1.36 Mlig455_025160, Mlig455_063937

Neo: -

Age: -

3.642 0.701 - 0.953 0.993 - 0.995

Mlig455_025160 {REF} {Length: 942} {RNA1310_54940} {RNA815_33690.1}

Mlig455_063937 {REF} {Length: 995} {RNA1310_54940} {RNA815_33690.1}
37. MligTC455_20015 52 1.09 Mlig455_026589

Neo: -

Age: -

3.64 - - 0.962 0.963 0.741 0.974 Mlig455_026589 {REF} {Length: 611} {RNA1310_66647} {RNA815_33955}
38. MligTC455_03841 920 19.16 Mlig455_018790, Mlig455_048140

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.474

Region-enriched R2: 5.915/0.00081

NKX2-1, NKX2-4 3.634 0.961 - 0.761 0.991 - 0.921

Mlig455_018790 {REF} {Length: 2203} {Pfam: Homeodomain [PF00046.31, score=72.7]} {Human: ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]; ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=2e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=8e-47]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=134, Expect=2e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=191, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401} {RNA815_21584}

Mlig455_048140 {REF} {Length: 2218} {Pfam: Homeodomain [PF00046.31, score=72.5]} {Human: ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=3e-39]; ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=144, Expect=6e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=2e-46]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=136, Expect=1e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=193, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401, RNA1509_12761} {RNA1509_12761, RNA815_21584}
39. MligTC455_19708 304 6.32 Mlig455_009784

Neo: -

Age: -

Region-enriched R2: 6.355/0.00039

3.634 0.910 - 0.898 0.834 - 0.992 Mlig455_009784 {REF} {Length: 826} {Pfam: Pancreatic hormone peptide [PF00159.20, score=43.3]} {RNA1509_54211} {RNA1310_54505.1, RNA1509_54211} {RNA1509_54211, RNA815_29389}
40. MligTC455_17021 49 1.02 Mlig455_030263

Neo: -

Age: -

3.633 0.710 - 0.967 0.963 - 0.993 Mlig455_030263 {REF} {Length: 566} {TRANSSPLICED} {Pfam: Galactosyltransferase [PF01762.23, score=23.7]} {Dmel: FBgn0000221, brn, brainiac, [Score=45.8, Expect=1e-06]} {RNA1310_35735} {RNA815_59866}
41. MligTC455_04786 26 0.55 Mlig455_043817, Mlig455_047431

Neo: -

Age: -

3.63 0.711 - 0.931 0.988 - 1.000

Mlig455_043817 {REF} {Length: 319} {NoTransDecoderORF} {RNA1310_64690}

Mlig455_047431 {REF} {Length: 2194} {Pfam: Glycine rich protein [PF12810.9, score=25.3]} {RNA1509_16377} {RNA1310_33363.2} {RNA815_25152}
42. MligTC455_31163 72 1.51 Mlig455_045625

Neo: -

Age: Up-Down-Down

3.629 0.714 - 0.979 0.956 - 0.980 Mlig455_045625 {REF} {Length: 1957} {RNA1509_21720} {RNA1310_14760, RNA1509_21720} {RNA1509_21720, RNA815_24583}
43. MligTC455_31164 572 11.91 Mlig455_029609, Mlig455_045673

Neo: -

Age: -

3.626 - - 0.942 0.977 0.732 0.975

Mlig455_029609 {REF} {Length: 746} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=39.4]} {Smed: dd_Smed_v6_22533_0_1, dd_Smed_v6_22533_0_1, [Score=48.5, Expect=1e-06]} {RNA1310_96354} {RNA815_44390}

Mlig455_045673 {REF} {Length: 2025} {RNA1509_21720} {RNA1310_14760} {RNA815_24583}
44. MligTC455_34115 6573 136.93 Mlig455_017846, Mlig455_047865

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.581

Region-enriched R2: 4.896/0.00130

3.622 0.817 - 0.893 0.955 - 0.957

Mlig455_017846 {REF} {Length: 1260} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1310_63880, RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701, RNA815_12890.1}

Mlig455_047865 {REF} {Length: 1135} {RNA1509_4845} {RNA1310_63880} {RNA815_12890.1}
45. MligTC455_41870 67 1.39 Mlig455_042417

Neo: -

Age: Up-Down-Up

ANGPTL1 3.618 - - 0.979 0.810 0.853 0.976 Mlig455_042417 {REF} {Length: 1469} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=110.4]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=102, Expect=6e-24]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=99.8, Expect=3e-23]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=104, Expect=6e-25]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=99.4, Expect=4e-23]} {Dmel: FBgn0003326, sca, scabrous, [Score=89.4, Expect=1e-19]} {Celegans: WBGene00017013, ensh-1, [Score=55.1, Expect=2e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=73.6, Expect=1e-14]} {RNA1509_28467} {RNA1310_67810} {RNA815_18070.1}
46. MligTC455_39890 162 3.37 Mlig455_047281, Mlig455_047331, Mlig455_069333

Neo: -

Age: -

Region-enriched R2: 6.097/0.00148

PLSCR1 3.616 0.708 - 0.940 0.971 - 0.997

Mlig455_047281 {REF} {Length: 1404} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_047331 {REF} {Length: 1395} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_069333 {REF} {Length: 1416} {Pfam: Scramblase [PF03803.17, score=248.7]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=226, Expect=1e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=228, Expect=2e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=223, Expect=1e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=224, Expect=2e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=4e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=304, Expect=2e-103]} {RNA1310_29769} {RNA815_41335}
47. MligTC455_43979 188 3.92 Mlig455_000082, Mlig455_063749

Neo: -

Age: -

GHSR 3.613 0.711 - 0.937 0.969 - 0.996

Mlig455_000082 {REF} {Length: 1342} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=53.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=18.2]} {Human: ENSG00000121853, GHSR, growth hormone secretagogue receptor, [Score=52.0, Expect=7e-07]} {Mouse: ENSMUSG00000051136, Ghsr, growth hormone secretagogue receptor, [Score=50.4, Expect=2e-06]} {Celegans: WBGene00018798, gnrr-1, GoNadotropin-Releasing hormone Receptor (GnRHR) related, [Score=48.9, Expect=3e-06]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=160, Expect=9e-47]} {RNA1310_30553}

Mlig455_063749 {REF} {Length: 1323} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.3]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.4]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=157, Expect=1e-45]} {RNA1310_30553}
48. MligTC455_37793 353 7.36 Mlig455_066109, Mlig455_068663

Neo: -

Age: Up-Down-Down

HMCN1 3.605 0.772 - 0.923 0.917 - 0.993

Mlig455_066109 {REF} {Length: 7924} {Pfam: Thrombospondin type 1 domain [PF00090.21, score=408.1]; Spondin-like TSP1 domain [PF19028.2, score=285.5]; Polycystin cation channel [PF08016.14, score=239.7]; PLAT/LH2 domain [PF01477.25, score=86.7]; Thrombospondin type 1 domain [PF19030.2, score=78.4]; Ion transport protein [PF00520.33, score=42.7]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=360, Expect=8e-99]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=363, Expect=7e-100]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [Score=199, Expect=5e-51]} {Celegans: WBGene00000082, adt-1, ADAMTS family; ADT-1, [RH, Score=306, Expect=4e-84]} {Smed: dd_Smed_v6_13975_0_1, dd_Smed_v6_13975_0_1, [RH, Score=944, Expect=0.0]} {RNA1509_9601} {RNA1310_488} {RNA815_1711}

Mlig455_068663 {REF} {Length: 7866} {Pfam: Thrombospondin type 1 domain [PF00090.21, score=423.7]; Spondin-like TSP1 domain [PF19028.2, score=299.7]; Thrombospondin type 1 domain [PF19030.2, score=92.3]; PLAT/LH2 domain [PF01477.25, score=23.1]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=338, Expect=1e-94]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=341, Expect=9e-96]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [Score=189, Expect=2e-48]} {Celegans: WBGene00000082, adt-1, ADAMTS family; ADT-1, [RH, Score=303, Expect=2e-84]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=282, Expect=3e-77]} {RNA1509_9601} {RNA1310_488} {RNA815_1711}
49. MligTC455_41035 366 7.62 Mlig455_000866

Neo: -

Age: logFC(26M/2M)=-0.773

Region-specific R2: 5.029

Region-enriched R2: 4.768/0.00000

3.591 0.865 - 0.952 0.790 - 0.984 Mlig455_000866 {REF} {Length: 1126} {Pfam: Pancreatic hormone peptide [PF00159.20, score=41.6]} {RNA1509_27581} {RNA1310_74103, RNA1509_27581} {RNA1509_27581, RNA815_38377}
50. MligTC455_16096 69 1.44 Mlig455_059809

Neo: -

Age: -

ANGPTL1 3.577 - 0.942 0.792 0.846 - 0.997 Mlig455_059809 {REF} {Length: 1391} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=117.9]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=109, Expect=1e-26]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=106, Expect=2e-25]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=110, Expect=3e-27]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=105, Expect=2e-25]} {Dmel: FBgn0003326, sca, scabrous, [Score=91.3, Expect=3e-20]} {Celegans: WBGene00017013, ensh-1, [Score=61.2, Expect=1e-10]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=77.8, Expect=5e-16]} {RNA1509_28467} {RNA1310_47262} {RNA815_18070.1}
51. MligTC455_42840 147 3.06 Mlig455_003645

Neo: -

Age: -

3.577 - - 0.966 0.980 0.755 0.876 Mlig455_003645 {REF} {Length: 1270} {RNA1509_48973} {RNA1310_36721} {RNA815_36286}
52. MligTC455_29915 50 1.04 Mlig455_027934

Neo: -

Age: Down-Up-Up

Region-enriched R2: 6.881/0.04464

ANGPTL1 3.572 0.708 - 0.932 0.933 - 0.999 Mlig455_027934 {REF} {Length: 2265} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=43.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=48.9, Expect=9e-06]} {Dmel: FBgn0031804, CG9500, [Score=53.1, Expect=9e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=49.7, Expect=1e-06]} {RNA1509_53291} {RNA1310_38229.1} {RNA815_10579.1}
53. MligTC455_19775 36 0.74 Mlig455_060359

Neo: -

Age: -

FCN1 3.57 0.711 - 0.929 0.983 - 0.947 Mlig455_060359 {REF} {Length: 1109} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.9]} {Human: ENSG00000085265, FCN1, ficolin 1, [Score=99.0, Expect=2e-23]; ENSG00000142748, FCN3, ficolin 3, [Score=99.0, Expect=1e-23]; ENSG00000160339, FCN2, ficolin 2, [Score=98.2, Expect=2e-23]} {Mouse: ENSMUSG00000026938, Fcna, ficolin A, [Score=100, Expect=3e-24]} {Dmel: FBgn0034160, CG5550, [Score=97.8, Expect=7e-24]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=90.1, Expect=4e-20]} {RNA1310_67383} {RNA815_45536}
54. MligTC455_12512 80 1.68 Mlig455_017689

Neo: -

Age: -

3.564 0.711 - 0.921 0.940 - 0.992 Mlig455_017689 {REF} {Length: 934} {RNA1310_37507} {RNA815_32171}
55. MligTC455_51334 326 6.78 Mlig455_011442, Mlig455_061180

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.828

3.564 0.858 - 0.977 0.734 - 0.995

Mlig455_011442 {REF} {Length: 742} {RNA1310_57576.1} {RNA815_29867}

Mlig455_061180 {REF} {Length: 769} {RNA1310_57576.1} {RNA815_29867}
56. MligTC455_27107 112 2.34 Mlig455_063632

Neo: -

Age: Up-Down-Down

3.562 - - 0.969 0.928 0.805 0.860 Mlig455_063632 {REF} {Length: 6095} {Pfam: TIR domain [PF13676.8, score=156.9]; Death domain [PF00531.24, score=29.6]; TIR domain [PF01582.22, score=27.3]} {Smed: dd_Smed_v6_12177_0_1, dd_Smed_v6_12177_0_1, [RH, Score=637, Expect=0.0]} {RNA1509_29883} {RNA1310_6245} {RNA815_1037}
57. MligTC455_46395 870 18.13 Mlig455_069471

Neo: -

Age: logFC(26M/2M)=0.458

PKD2 3.557 0.793 - 0.866 0.927 - 0.971 Mlig455_069471 {REF} {Length: 3122} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.8]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=750, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=8e-123]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
58. MligTC455_18099 24 0.51 Mlig455_036525

Neo: -

Age: -

PPA1 3.557 0.711 - 0.933 0.925 - 0.988 Mlig455_036525 {REF} {Length: 1911} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1310_57333.1} {RNA815_22340}
59. MligTC455_39097 57 1.18 Mlig455_051961

Neo: -

Age: -

Region-enriched R4: 5.550/0.02060

3.555 - - 0.967 0.772 0.824 0.992 Mlig455_051961 {REF} {Length: 1972} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=65.0]} {RNA1509_13138} {RNA1310_34740} {RNA815_15663}
60. MligTC455_45021 381 7.95 Mlig455_046686

Neo: -

Age: Down-Up-Up

Region-enriched R2: 3.428/0.03156

AVP 3.551 0.817 - 0.969 0.778 - 0.987 Mlig455_046686 {REF} {Length: 1388} {Pfam: Neurohypophysial hormones, C-terminal Domain [PF00184.19, score=36.2]} {Human: ENSG00000101200, AVP, arginine vasopressin, [Score=54.3, Expect=2e-09]} {Mouse: ENSMUSG00000037727, Avp, arginine vasopressin, [Score=53.1, Expect=3e-09]} {RNA1509_50574} {RNA1310_38922} {RNA815_23813}
61. MligTC455_40989 801 16.68 Mlig455_016294

Neo: -

Age: logFC(26M/2M)=0.270

PKD2 3.548 0.814 - 0.947 0.788 - 0.999 Mlig455_016294 {REF} {Length: 3179} {Pfam: Polycystin cation channel [PF08016.14, score=486.5]; Ion transport protein [PF00520.33, score=90.3]; EF hand [PF00036.34, score=23.7]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=718, Expect=0.0]; ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [RH, Score=712, Expect=0.0]} {Mouse: ENSMUSG00000037578, Pkd2l1, polycystic kidney disease 2-like 1, [RH, Score=704, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [RH, Score=310, Expect=2e-91]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [RH, Score=370, Expect=7e-116]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_14023, RNA1509_24240} {RNA1310_4836.1, RNA1509_14023, RNA1509_24240} {RNA1509_14023, RNA1509_24240, RNA815_4677}
62. MligTC455_49919 745 15.52 Mlig455_017182, Mlig455_048150

Neo: -

Age: -

Region-specific R2: 7.180

Region-enriched R2: 7.978/0.00000

Regeneration-downregulated R2: -4.649

Regeneration-depleted R2: -4.649

3.548 0.866 - 0.955 0.732 - 0.995

Mlig455_017182 {REF} {Length: 576} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1310_60849, RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1509_35830, RNA1509_49816, RNA1509_53987, RNA815_31347}

Mlig455_048150 {REF} {Length: 574} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830} {RNA1310_60849} {RNA815_31347}
63. MligTC455_33463 240 4.99 Mlig455_023684

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.110/0.00054

PKD1L2 3.542 - - 0.892 0.871 0.782 0.997 Mlig455_023684 {REF} {Length: 12137} {Pfam: Polycystin cation channel [PF08016.14, score=271.5]; PKD domain [PF00801.22, score=88.3]; PLAT/LH2 domain [PF01477.25, score=72.6]; PKD domain [PF18911.2, score=49.9]; Ion transport protein [PF00520.33, score=46.0]; F5/8 type C domain [PF00754.27, score=33.9]} {Human: ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [RH, Score=263, Expect=2e-69]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=272, Expect=3e-72]} {Dmel: FBgn0050048, CG30048, [Score=57.4, Expect=3e-07]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=144, Expect=2e-33]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=518, Expect=3e-147]} {RNA1509_5488} {RNA1310_100} {RNA815_3211}
64. MligTC455_48034 2940 61.24 Mlig455_019197

Neo: -

Age: Down-Up-Down

Region-specific R2: 3.626

Region-enriched R2: 3.016/0.00000

3.532 0.960 - 0.858 0.814 - 0.900 Mlig455_019197 {REF} {Length: 837} {TRANSSPLICED} {RNA1509_18675, RNA1509_21674, RNA1509_29285, RNA1509_6143} {RNA1310_17472, RNA1509_18675, RNA1509_21674, RNA1509_29285, RNA1509_6143} {RNA1509_18675, RNA1509_21674, RNA1509_29285, RNA1509_6143, RNA815_19105}
65. MligTC455_29050 162 3.38 Mlig455_004578

Neo: -

Age: -

TMEM30A 3.525 - - 0.966 0.703 0.894 0.962 Mlig455_004578 {REF} {Length: 3215} {TRANSSPLICED} {Pfam: LEM3 (ligand-effect modulator 3) family / CDC50 family [PF03381.17, score=266.2]} {Human: ENSG00000112697, TMEM30A, transmembrane protein 30A, [Score=210, Expect=3e-64]} {Mouse: ENSMUSG00000032328, Tmem30a, transmembrane protein 30A, [Score=214, Expect=4e-66]} {Dmel: FBgn0030752, CG9947, [Score=253, Expect=1e-81]} {Celegans: WBGene00019946, chat-1, CDC50 family protein chat-1, [Score=218, Expect=8e-68]} {Smed: dd_Smed_v6_6430_0_1, dd_Smed_v6_6430_0_1, [Score=258, Expect=9e-84]} {RNA1509_38539} {RNA1310_9371} {RNA815_12157}
66. MligTC455_19524 100 2.09 Mlig455_010263

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.437/0.01311

3.525 - - 0.792 0.928 0.836 0.969 Mlig455_010263 {REF} {Length: 2969} {RNA1310_11925.1} {RNA815_27110}
67. MligTC455_46313 525 10.93 Mlig455_061072, Mlig455_061118

Neo: -

Age: Down-Up-Down

3.522 - 0.977 0.898 0.715 - 0.932

Mlig455_061072 {REF} {Length: 1336} {Pfam: Stathmin family [PF00836.21, score=30.8]} {Smed: dd_Smed_v6_512_0_1, dd_Smed_v6_512_0_1, [Score=63.2, Expect=3e-14]} {RNA1509_8850} {RNA1310_39143} {RNA815_16363}

Mlig455_061118 {REF} {Length: 1813} {Pfam: Stathmin family [PF00836.21, score=27.4]} {Smed: dd_Smed_v6_512_0_1, dd_Smed_v6_512_0_1, [Score=63.5, Expect=2e-14]} {RNA1509_8850} {RNA1310_39143} {RNA815_16363}
68. MligTC455_50355 38 0.79 Mlig455_057631

Neo: -

Age: -

Region-enriched R2: 7.639/0.01837

3.522 0.705 - 0.966 0.858 - 0.993 Mlig455_057631 {REF} {Length: 1003} {Pfam: WSC domain [PF01822.21, score=45.2]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=6e-06]} {RNA1310_44307} {RNA815_33128}
69. MligTC455_46067 548 11.42 Mlig455_054518, Mlig455_055436, Mlig455_055448

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.305/0.04262

GRIK3, GRIK4 3.521 0.848 - 0.725 0.957 - 0.991

Mlig455_054518 {REF} {Length: 4725} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=91.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.2]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=222, Expect=5e-60]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=222, Expect=6e-60]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=218, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=3e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=215, Expect=1e-57]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=9e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=213, Expect=9e-57]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=224, Expect=2e-60]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=224, Expect=9e-61]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=220, Expect=2e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=215, Expect=1e-57]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=296, Expect=6e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=312, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_14215, RNA1509_40992} {RNA1310_5620.1, RNA1509_14215, RNA1509_40992} {RNA1509_14215, RNA1509_40992, RNA815_1965}

Mlig455_055436 {REF} {Length: 4732} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=6e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=7e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=7e-59]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=9e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=211, Expect=2e-56]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=226, Expect=3e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_40992} {RNA1310_5620.1} {RNA815_1965}

Mlig455_055448 {REF} {Length: 4726} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=9e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=9e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=8e-59]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=217, Expect=2e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=7e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=6e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=225, Expect=4e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=217, Expect=9e-59]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=5e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_32892, RNA1509_40992} {RNA1310_5620.1, RNA1509_32892} {RNA1509_32892, RNA815_1965}
70. MligTC455_41339 61 1.27 Mlig455_021120

Neo: -

Age: -

3.515 - - 0.968 0.730 0.823 0.994 Mlig455_021120 {REF} {Length: 294} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_118897} {RNA815_62550}
71. MligTC455_23567 109 2.27 Mlig455_013185

Neo: -

Age: Down-Up-Down

BCHE 3.514 0.769 - 0.932 0.979 0.834 - Mlig455_013185 {REF} {Length: 4455} {Pfam: Carboxylesterase family [PF00135.30, score=432.1]; alpha/beta hydrolase fold [PF07859.15, score=35.5]} {Human: ENSG00000114200, BCHE, butyrylcholinesterase, [Score=317, Expect=9e-99]; ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=312, Expect=2e-96]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [Score=324, Expect=3e-101]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=249, Expect=8e-73]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=327, Expect=2e-102]} {Smed: dd_Smed_v6_15930_0_1, dd_Smed_v6_15930_0_1, [RH, Score=412, Expect=4e-134]} {RNA1509_26775} {RNA1310_8383.1} {RNA815_10983}
72. MligTC455_43072 81 1.68 Mlig455_042521

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.590/0.02161

3.513 0.787 - 0.964 0.774 - 0.988 Mlig455_042521 {REF} {Length: 1049} {RNA1509_46101} {RNA1310_32444} {RNA815_30668}
73. MligTC455_19410 194 4.04 Mlig455_047838

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.170

Region-enriched R2: 5.689/0.00000

3.507 - 0.981 0.733 - 0.850 0.943 Mlig455_047838 {REF} {Length: 724} {TRANSSPLICED} {RNA1509_54915} {RNA1310_53549} {RNA815_27051}
74. MligTC455_29045 127 2.65 Mlig455_056054

Neo: -

Age: -

Region-enriched R2: 4.858/0.00652

FZD5 3.499 0.719 - - 0.866 0.918 0.996 Mlig455_056054 {REF} {Length: 3655} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=389.0]; Fz domain [PF01392.24, score=85.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=554, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [Score=561, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=516, Expect=5e-176]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=368, Expect=3e-120]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [Score=522, Expect=7e-178]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
75. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 3.496 0.717 - 0.944 0.854 - 0.981 Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
76. MligTC455_39544 611 12.73 Mlig455_001809, Mlig455_001836, Mlig455_062227, Mlig455_062236

Neo: -

Age: -

Region-specific R2: 8.576

Region-enriched R2: 8.112/0.00016

3.49 0.855 - 0.955 - 0.774 0.906

Mlig455_001809 {REF} {Length: 1067} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}

Mlig455_001836 {REF} {Length: 1065} {RNA1509_52939} {RNA1310_72581, RNA1509_52939} {RNA1509_52939, RNA815_24546}

Mlig455_062227 {REF} {Length: 3520} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}

Mlig455_062236 {REF} {Length: 620} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}
77. MligTC455_41036 281 5.86 Mlig455_057198

Neo: -

Age: -

Region-specific R2: 5.284

Region-enriched R2: 4.243/0.00075

3.49 0.860 - 0.826 0.812 - 0.992 Mlig455_057198 {REF} {Length: 538} {Pfam: Pancreatic hormone peptide [PF00159.20, score=41.9]} {RNA1509_42071} {RNA1310_74103, RNA1509_42071} {RNA1509_42071, RNA815_38377}
78. MligTC455_17701 1279 26.65 Mlig455_051483

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.592

Region-enriched R2: 6.602/0.00000
Region-enriched R3: 2.598/0.04295

3.484 0.851 - 0.966 0.928 - 0.739 Mlig455_051483 {REF} {Length: 1833} {RNA1509_14131} {RNA1310_69964.2, RNA1509_14131} {RNA1509_14131, RNA815_35453.1}
79. MligTC455_21755 70 1.47 Mlig455_021213

Neo: -

Age: -

3.484 0.700 - 0.855 0.937 - 0.992 Mlig455_021213 {REF} {Length: 4215} {Pfam: F5/8 type C domain [PF00754.27, score=55.5]} {RNA1509_2515} {RNA1310_33166} {RNA815_14716}
80. MligTC455_32644 41 0.86 Mlig455_043770, Mlig455_043786

Neo: -

Age: -

Region-enriched R2: 6.705/0.00336

3.484 0.702 - 0.953 0.834 - 0.995

Mlig455_043770 {REF} {Length: 1011} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.8, Expect=3e-11]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}

Mlig455_043786 {REF} {Length: 1348} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
81. MligTC455_29914 44 0.91 Mlig455_027923

Neo: -

Age: Down-Up-Down

Region-enriched R2: 8.096/0.00455

ANGPTL3 3.476 0.706 - 0.949 0.840 - 0.981 Mlig455_027923 {REF} {Length: 1663} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=70.5]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=60.5, Expect=9e-10]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=59.3, Expect=2e-09]; ENSG00000120332, TNN, tenascin N, [Score=58.9, Expect=3e-09]} {Mouse: ENSMUSG00000015829, Tnr, tenascin R, [Score=62.4, Expect=2e-10]} {Dmel: FBgn0031804, CG9500, [Score=76.3, Expect=6e-16]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=51.2, Expect=3e-07]} {RNA1509_53291} {RNA1310_58974} {RNA815_43288.3}
82. MligTC455_29118 467 9.72 Mlig455_040411

Neo: -

Age: -

Region-specific R2: 6.456

Region-enriched R2: 5.344/0.00023

3.474 0.980 - 0.970 0.793 - 0.731 Mlig455_040411 {REF} {Length: 599} {TRANSSPLICED} {RNA1509_53840} {RNA1310_67192, RNA1509_53840} {RNA1509_53840, RNA815_27042}
83. MligTC455_19279 4576 95.33 Mlig455_057411

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.654

Region-specific R2: 5.173

Region-enriched R2: 4.585/0.00000
Region-enriched R3: 2.611/0.00003

CHRNA10 3.473 - - 0.841 0.909 0.763 0.960 Mlig455_057411 {REF} {Length: 1075} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=85.3]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=91.3, Expect=1e-20]} {Mouse: ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=92.0, Expect=7e-21]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=88.2, Expect=1e-19]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=110, Expect=2e-27]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=120, Expect=4e-31]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=96.3, Expect=8e-23]} {RNA1509_1306} {RNA1310_34970} {RNA815_15305.1}
84. MligTC455_38288 5006 104.28 Mlig455_045260, Mlig455_069180

Neo: -

Age: logFC(26M/2M)=0.302

Region-specific R2: 4.563

Region-enriched R2: 3.648/0.00002

RNF217 3.464 - - 0.921 0.956 0.878 0.709

Mlig455_045260 {REF} {Length: 2327} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=53.3]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=129, Expect=8e-31]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=124, Expect=1e-29]} {Dmel: FBgn0031857, LUBEL, Linear Ubiquitin E3 ligase, [Score=56.2, Expect=1e-07]} {Smed: dd_Smed_v6_7110_0_1, dd_Smed_v6_7110_0_1, [Score=114, Expect=1e-26]} {RNA1509_27317} {RNA1310_23955} {RNA815_6068}

Mlig455_069180 {REF} {Length: 2719} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=54.2]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=130, Expect=3e-31]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=125, Expect=4e-30]} {Dmel: FBgn0031857, LUBEL, Linear Ubiquitin E3 ligase, [Score=55.8, Expect=1e-07]} {Smed: dd_Smed_v6_7110_0_1, dd_Smed_v6_7110_0_1, [Score=113, Expect=3e-26]} {RNA1509_27317} {RNA1310_23955} {RNA815_6068}
85. MligTC455_50253 44 0.92 Mlig455_031495

Neo: -

Age: -

GABRB2 3.459 0.705 - 0.959 0.798 - 0.997 Mlig455_031495 {REF} {Length: 2129} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=58.3]} {Human: ENSG00000145864, GABRB2, gamma-aminobutyric acid type A receptor beta2 subunit, [Score=71.2, Expect=6e-14]} {Mouse: ENSMUSG00000007653, Gabrb2, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2, [Score=67.8, Expect=1e-12]; ENSMUSG00000029212, Gabrb1, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1, [Score=67.4, Expect=1e-12]} {Dmel: FBgn0024963, GluClalpha, [Score=54.3, Expect=3e-08]} {Celegans: WBGene00001594, glc-4, Glutamate-gated ChLoride channel, [Score=66.6, Expect=2e-12]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=70.1, Expect=9e-14]} {RNA1310_46931} {RNA815_25428}
86. MligTC455_27106 105 2.18 Mlig455_022612

Neo: -

Age: Up-Down-Down

3.456 - - 0.962 0.876 0.777 0.841 Mlig455_022612 {REF} {Length: 6144} {TRANSSPLICED} {Pfam: TIR domain [PF13676.8, score=157.1]; TIR domain [PF01582.22, score=29.6]; Death domain [PF00531.24, score=29.1]} {Smed: dd_Smed_v6_12177_0_1, dd_Smed_v6_12177_0_1, [RH, Score=638, Expect=0.0]} {RNA1509_29883, RNA1509_42445, RNA1509_47365} {RNA1310_6245, RNA1509_29883, RNA1509_42445, RNA1509_47365} {RNA1509_29883, RNA1509_42445, RNA1509_47365, RNA815_1037}
87. MligTC455_53190 105 2.18 Mlig455_013516

Neo: -

Age: -

SCNN1B 3.456 0.721 - 0.851 0.976 - 0.908 Mlig455_013516 {REF} {Length: 2819} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=290.8]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=158, Expect=8e-41]} {Mouse: ENSMUSG00000000216, Scnn1g, sodium channel, nonvoltage-gated 1 gamma, [Score=149, Expect=1e-37]} {Dmel: FBgn0051105, ppk22, pickpocket 22, [RH, Score=60.1, Expect=3e-09]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [RH, Score=166, Expect=2e-43]} {Smed: dd_Smed_v6_17021_0_1, dd_Smed_v6_17021_0_1, [RH, Score=186, Expect=1e-51]} {RNA1509_18670} {RNA1310_20526} {RNA815_9932}
88. MligTC455_34952 124 2.59 Mlig455_012890

Neo: -

Age: Up-Down-Down

Region-enriched R7: 3.857/0.02491

ANGPTL7 3.445 - - 0.846 0.853 0.973 0.773 Mlig455_012890 {REF} {Length: 1624} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=123.8]} {Human: ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=102, Expect=1e-24]; ENSG00000120332, TNN, tenascin N, [Score=101, Expect=3e-23]; ENSG00000101280, ANGPT4, angiopoietin 4, [Score=98.2, Expect=2e-22]} {Mouse: ENSMUSG00000028989, Angptl7, angiopoietin-like 7, [Score=100, Expect=4e-24]; ENSMUSG00000026725, Tnn, tenascin N, [Score=97.4, Expect=4e-22]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=97.1, Expect=2e-22]} {Dmel: FBgn0034160, CG5550, [Score=107, Expect=2e-27]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=108, Expect=2e-26]} {RNA1509_54507} {RNA1310_26965} {RNA815_12335}
89. MligTC455_16873 645 13.43 Mlig455_006290

Neo: -

Age: Down-Up-Up

Region-enriched R2: 2.543/0.01560

3.438 0.792 - - 0.910 0.784 0.952 Mlig455_006290 {REF} {Length: 699} {RNA1310_48111} {RNA815_24753}
90. MligTC455_42645 144 3 Mlig455_012431

Neo: -

Age: -

KRT8 3.432 0.763 - 0.973 - 0.929 0.767 Mlig455_012431 {REF} {Length: 3911} {Pfam: Intermediate filament protein [PF00038.23, score=141.4]; BRE1 E3 ubiquitin ligase [PF08647.13, score=19.8]; Protein of unknown function (DUF3450) [PF11932.10, score=18.3]} {Human: ENSG00000170421, KRT8, keratin 8, [RH, Score=109, Expect=9e-25]; ENSG00000185640, KRT79, keratin 79, [RH, Score=105, Expect=2e-23]} {Mouse: ENSMUSG00000063661, Krt73, keratin 73, [RH, Score=104, Expect=2e-23]} {Dmel: FBgn0010397, LamC, Lamin C, [Score=138, Expect=2e-34]} {Celegans: WBGene00002050, ifa-1, Intermediate filament protein ifa-1, [Score=246, Expect=3e-74]} {Smed: dd_Smed_v6_3871_0_1, dd_Smed_v6_3871_0_1, [Score=271, Expect=9e-84]} {RNA1310_10400} {RNA815_12264}
91. MligTC455_50664 138 2.87 Mlig455_035152

Neo: -

Age: -

Region-enriched R2: 3.712/0.01441

LRRC74A 3.429 - - 0.776 0.790 0.904 0.959 Mlig455_035152 {REF} {Length: 2523} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=68.7]; Leucine Rich Repeat [PF00560.35, score=35.6]; Leucine Rich repeats (2 copies) [PF12799.9, score=31.8]; Leucine rich repeat [PF13855.8, score=22.7]} {Human: ENSG00000100565, LRRC74A, leucine rich repeat containing 74A, [Score=146, Expect=1e-37]; ENSG00000187905, LRRC74B, leucine rich repeat containing 74B, [Score=144, Expect=1e-37]} {Mouse: ENSMUSG00000059114, Lrrc74a, leucine rich repeat containing 74A, [Score=147, Expect=5e-38]; ENSMUSG00000022759, Lrrc74b, leucine rich repeat containing 74B, [Score=144, Expect=1e-37]} {Dmel: FBgn0033212, LRR, Leucine-rich repeat, [Score=51.6, Expect=2e-06]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=55.5, Expect=8e-08]} {Smed: dd_Smed_v6_14506_0_1, dd_Smed_v6_14506_0_1, [Score=147, Expect=6e-38]} {RNA1509_21228} {RNA1310_12842} {RNA815_17243}
92. MligTC455_05098 127 2.65 Mlig455_009525, Mlig455_009531

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.095/0.01821

KCNH7 3.429 0.731 - 0.961 0.918 - 0.819

Mlig455_009525 {REF} {Length: 2109} {Pfam: Ion transport protein [PF00520.33, score=111.8]; Ion channel [PF07885.18, score=46.1]; Cyclic nucleotide-binding domain [PF00027.31, score=36.3]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=29.8]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=528, Expect=4e-176]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=509, Expect=2e-170]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=505, Expect=9e-167]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=527, Expect=4e-175]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=510, Expect=3e-171]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=504, Expect=9e-167]} {Dmel: FBgn0003353, sei, seizure, [Score=507, Expect=2e-171]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=496, Expect=1e-169]} {Smed: dd_Smed_v6_12978_0_1, dd_Smed_v6_12978_0_1, [Score=608, Expect=0.0]} {RNA1509_56964} {RNA1310_41939} {RNA815_5858.1}

Mlig455_009531 {REF} {Length: 3631} {Pfam: Ion transport protein [PF00520.33, score=110.4]; Ion channel [PF07885.18, score=45.2]; Cyclic nucleotide-binding domain [PF00027.31, score=43.3]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=619, Expect=0.0]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=597, Expect=0.0]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=596, Expect=0.0]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=617, Expect=0.0]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=602, Expect=0.0]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=596, Expect=0.0]} {Dmel: FBgn0003353, sei, seizure, [Score=591, Expect=0.0]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=579, Expect=0.0]} {Smed: dd_Smed_v6_12978_0_4, dd_Smed_v6_12978_0_4, [RH, Score=716, Expect=0.0]} {RNA1509_56964} {RNA1310_23186, RNA1509_56964} {RNA1509_56964, RNA815_5858.2}
93. MligTC455_52629 472 9.83 Mlig455_059435

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.775

Region-enriched R2: 6.727/0.00002

3.427 0.744 - 0.983 0.704 - 0.996 Mlig455_059435 {REF} {Length: 726} {RNA1509_48505} {RNA1310_62885} {RNA815_39881}
94. MligTC455_53240 1601 33.35 Mlig455_025555

Neo: -

Age: -

Region-specific R2: 4.178

Region-enriched R2: 2.883/0.00000

3.426 - - 0.784 0.892 0.770 0.980 Mlig455_025555 {REF} {Length: 2163} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=28.0]} {Dmel: FBgn0051221, CG31221, [RH, Score=69.7, Expect=2e-14]} {Celegans: WBGene00010290, F58H1.7, [Score=64.7, Expect=4e-13]} {Smed: dd_Smed_v6_2598_0_1, dd_Smed_v6_2598_0_1, [RH, Score=168, Expect=3e-53]} {RNA1509_58542} {RNA1310_40950, RNA1509_58542} {RNA1509_58542, RNA815_19778.1}
95. MligTC455_24302 149 3.11 Mlig455_035632

Neo: -

Age: Up-Down-Up

KCNQ5 3.424 - - 0.901 0.795 0.740 0.988 Mlig455_035632 {REF} {Length: 2263} {Pfam: KCNQ voltage-gated potassium channel [PF03520.16, score=124.6]} {Human: ENSG00000185760, KCNQ5, potassium voltage-gated channel subfamily Q member 5, [Score=122, Expect=1e-28]; ENSG00000117013, KCNQ4, potassium voltage-gated channel subfamily Q member 4, [Score=121, Expect=2e-28]} {Mouse: ENSMUSG00000028033, Kcnq5, potassium voltage-gated channel, subfamily Q, member 5, [Score=121, Expect=1e-28]; ENSMUSG00000028631, Kcnq4, potassium voltage-gated channel, subfamily Q, member 4, [Score=119, Expect=4e-28]} {Dmel: FBgn0033494, KCNQ, KCNQ potassium channel, [Score=175, Expect=1e-46]} {Celegans: WBGene00002235, kqt-3, KQT-3 potassium channel; Potassium channel, KvQLT family, [Score=110, Expect=1e-25]} {Smed: dd_Smed_v6_17359_0_2, dd_Smed_v6_17359_0_2, [Score=186, Expect=2e-52]} {RNA1509_34272} {RNA1310_3730.1} {RNA815_2787}
96. MligTC455_13963 31 0.64 Mlig455_052027

Neo: -

Age: Down-Up-Down

3.421 0.711 - 0.921 0.793 - 0.996 Mlig455_052027 {REF} {Length: 1717} {RNA1509_48973} {RNA1310_34931} {RNA815_59614}
97. MligTC455_51933 583 12.15 Mlig455_024511

Neo: -

Age: logFC(26M/2M)=-0.429

Region-enriched R2: 2.089/0.00081

CBSL 3.413 0.780 0.951 0.833 - - 0.849 Mlig455_024511 {REF} {Length: 1959} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=138.0]; CBS domain [PF00571.30, score=48.9]} {Human: ENSG00000274276, CBSL, cystathionine-beta-synthase like, [Score=463, Expect=3e-160]; ENSG00000160200, CBS, cystathionine-beta-synthase, [Score=463, Expect=3e-160]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [Score=467, Expect=6e-162]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [Score=327, Expect=2e-107]} {Celegans: WBGene00013866, cbs-1, Cystathionine Beta-Synthase, [Score=264, Expect=2e-81]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [Score=511, Expect=6e-180]} {RNA1509_36721} {RNA1310_10809} {RNA815_3797.1}
98. MligTC455_18499 24 0.5 Mlig455_012628

Neo: -

Age: -

3.409 0.703 - 0.910 0.827 - 0.969 Mlig455_012628 {REF} {Length: 1340} {Smed: dd_Smed_v6_500_0_1, dd_Smed_v6_500_0_1, [Score=60.5, Expect=1e-10]} {RNA1310_107419} {RNA815_46554}
99. MligTC455_46430 62 1.29 Mlig455_057117, Mlig455_069301

Neo: -

Age: -

GUCY2F 3.408 0.705 - 0.940 0.772 - 0.991

Mlig455_057117 {REF} {Length: 2651} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=196.0]; Nitrate and nitrite sensing [PF08376.12, score=82.5]; Heme NO binding associated [PF07701.16, score=28.2]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=247, Expect=9e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=242, Expect=3e-68]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=238, Expect=5e-67]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=246, Expect=7e-70]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=242, Expect=2e-68]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=241, Expect=7e-68]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=239, Expect=3e-67]} {Dmel: FBgn0053958, CG33958, [Score=266, Expect=4e-79]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=235, Expect=3e-66]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=238, Expect=4e-67]} {RNA1509_38781} {RNA1310_35456} {RNA815_22108}

Mlig455_069301 {REF} {Length: 2370} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=178.1]; Nitrate and nitrite sensing [PF08376.12, score=82.3]; Heme NO binding associated [PF07701.16, score=28.0]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=232, Expect=2e-64]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=232, Expect=1e-64]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=225, Expect=5e-62]} {Dmel: FBgn0053958, CG33958, [Score=250, Expect=5e-73]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=223, Expect=1e-61]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=221, Expect=4e-61]} {RNA1509_38781} {RNA1310_35456} {RNA815_24181}
100. MligTC455_15949 37 0.76 Mlig455_059880

Neo: -

Age: -

3.403 0.720 - 0.975 0.737 - 0.971 Mlig455_059880 {REF} {Length: 1226} {Pfam: Lectin C-type domain [PF00059.23, score=39.5]} {Dmel: FBgn0031373, CG15358, [Score=52.8, Expect=4e-08]} {RNA1310_120903}

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