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Results for MligTC455_45627

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_45627 651 13.56 Mlig455_061482

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.553

Mlig455_061482 {REF} {Length: 1575} {TRANSSPLICED} {RNA1509_20102, RNA1509_52016, RNA1509_54334} {RNA1310_14542, RNA1509_20102, RNA1509_52016, RNA1509_54334} {RNA1509_20102, RNA1509_52016, RNA1509_54334, RNA815_8538.2}

Cumulative graph for MligTC455_45627

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.313 3.898 0.75920 1.00000
RegionR2 0.994 3.898 0.06591 0.31111
RegionR3 0.099 3.898 0.83734 1.00000
RegionR4 -0.17 3.898 0.75896 1.00000
RegionR5 -0.567 3.898 0.24891 0.56437
RegionR6 0.261 3.898 0.59359 1.00000
RegionR7 -0.44 3.898 0.48104 1.00000
RegionR8 0.136 3.898 0.84372 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.601 3.898 0.04582 0.68092
RegenerationR2 0.306 3.898 0.56441 0.90062
RegenerationR3 -1.088 3.898 0.06449 0.42796
RegenerationR4 -1.044 3.898 0.08189 0.45231
RegenerationR5 -0.62 3.898 0.30558 0.73293
RegenerationR6 -1.167 3.898 0.06444 0.31884
RegenerationBL -0.271 3.898 0.66519 0.99905
RegenerationTP 0.918 3.898 0.14185 0.56151


Genes with expression patterns similar to MligTC455_45627

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_45627 651 13.56 Mlig455_061482

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.553

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_061482 {REF} {Length: 1575} {TRANSSPLICED} {RNA1509_20102, RNA1509_52016, RNA1509_54334} {RNA1310_14542, RNA1509_20102, RNA1509_52016, RNA1509_54334} {RNA1509_20102, RNA1509_52016, RNA1509_54334, RNA815_8538.2}
2. MligTC455_42188 714 14.88 Mlig455_004983

Neo: -

Age: -

4.259 0.798 - 0.912 0.764 0.956 0.829 Mlig455_004983 {REF} {Length: 958} {RNA1509_36666, RNA1509_48333} {RNA1310_81420, RNA1509_36666, RNA1509_48333} {RNA1509_36666, RNA1509_48333, RNA815_25950}
3. MligTC455_46347 760 15.83 Mlig455_023024

Neo: -

Age: Down-Up-Up

ELOF1 3.478 - - 0.855 0.900 0.957 0.766 Mlig455_023024 {REF} {Length: 1056} {TRANSSPLICED} {Pfam: Transcription elongation factor Elf1 like [PF05129.15, score=104.0]} {Human: ENSG00000130165, ELOF1, elongation factor 1 homolog, [RH, Score=102, Expect=2e-29]} {Mouse: ENSMUSG00000013822, Elof1, ELF1 homolog, elongation factor 1, [RH, Score=101, Expect=1e-29]} {Dmel: FBgn0063670, CG40228, [RH, Score=133, Expect=2e-42]} {Celegans: WBGene00013219, Y54G11A.11, Transcription elongation factor 1 homolog, [RH, Score=134, Expect=6e-43]} {Smed: dd_Smed_v6_3505_0_1, dd_Smed_v6_3505_0_1, [RH, Score=122, Expect=2e-38]} {RNA1509_44595, RNA1509_9167} {RNA1310_32925, RNA1509_44595} {RNA1509_44595, RNA815_15186.1}
4. MligTC455_44186 185 3.85 Mlig455_052492

Neo: -

Age: -

3.448 0.849 - 0.928 - 0.953 0.718 Mlig455_052492 {REF} {Length: 959} {Pfam: Lectin C-type domain [PF00059.23, score=33.2]} {RNA1509_20946} {RNA1310_41618} {RNA815_32434}
5. MligTC455_27901 200 4.17 Mlig455_028860

Neo: -

Age: -

RNF213 3.404 0.750 0.791 - 0.889 0.974 - Mlig455_028860 {REF} {Length: 7501} {Human: ENSG00000173821, RNF213, ring finger protein 213, [Score=81.6, Expect=2e-15]} {Mouse: ENSMUSG00000070327, Rnf213, ring finger protein 213, [Score=72.8, Expect=7e-13]} {RNA1509_4697} {RNA1310_300.1} {RNA815_205.1}
6. MligTC455_17678 121 2.53 Mlig455_036741

Neo: -

Age: -

Region-enriched R2: 3.030/0.00234

Regeneration-downregulated R4: -3.160

Regeneration-depleted R4: -3.160

TNNC2 3.354 0.806 - - 0.854 0.973 0.721 Mlig455_036741 {REF} {Length: 924} {Pfam: EF-hand domain pair [PF13499.8, score=100.6]; EF-hand domain [PF13405.8, score=75.3]; EF hand [PF00036.34, score=73.4]; EF-hand domain pair [PF13833.8, score=55.4]; EF hand [PF13202.8, score=44.0]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=23.7]; EF-hand domain [PF14658.8, score=20.3]} {Human: ENSG00000101470, TNNC2, troponin C2, fast skeletal type, [Score=74.7, Expect=4e-17]} {Mouse: ENSMUSG00000017300, Tnnc2, troponin C2, fast, [Score=74.7, Expect=3e-17]} {Dmel: FBgn0040351, CG11638, [Score=68.6, Expect=5e-14]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=72.0, Expect=3e-16]} {Smed: dd_Smed_v6_4669_0_1, dd_Smed_v6_4669_0_1, [Score=68.2, Expect=4e-15]} {RNA1310_42119} {RNA815_21011}
7. MligTC455_23082 1608 33.5 Mlig455_024173

Neo: -

Age: -

FAT4 3.25 - 0.707 - 0.782 0.970 0.791 Mlig455_024173 {REF} {Length: 8284} {Pfam: Cadherin domain [PF00028.19, score=731.9]; Cadherin-like [PF16184.7, score=111.8]; Cadherin-like [PF08266.14, score=26.5]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=544, Expect=2e-155]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=514, Expect=2e-146]} {Dmel: FBgn0284247, ds, dachsous, [Score=463, Expect=8e-131]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=276, Expect=4e-74]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=279, Expect=7e-75]} {RNA1509_848} {RNA1310_296} {RNA815_105}
8. MligTC455_41695 251 5.23 Mlig455_044756

Neo: -

Age: logFC(26M/2M)=-0.724

Regeneration-downregulated R4: -3.389

Regeneration-depleted R4: -3.389

SSUH2 3.116 0.739 0.714 - - 0.958 0.705 Mlig455_044756 {REF} {Length: 1704} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=186, Expect=9e-55]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=157, Expect=2e-44]} {RNA1509_35286} {RNA1310_22184} {RNA815_11262}
9. MligTC455_37753 410 8.54 Mlig455_054901, Mlig455_065604

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.475

Region-enriched R2: 4.050/0.00069

2.783 0.871 - - 0.946 0.966 -

Mlig455_054901 {REF} {Length: 2445} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=23.2]} {Celegans: WBGene00010315, F59B2.13, Putative G-protein coupled receptor F59B2.13, [RH, Score=58.5, Expect=6e-09]} {Smed: dd_Smed_v6_28468_0_1, dd_Smed_v6_28468_0_1, [Score=88.6, Expect=1e-18]} {RNA1509_30384} {RNA1310_34563.1} {RNA815_18979}

Mlig455_065604 {REF} {Length: 2387} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=22.9]} {Celegans: WBGene00010315, F59B2.13, Putative G-protein coupled receptor F59B2.13, [Score=55.1, Expect=9e-08]} {Smed: dd_Smed_v6_28468_0_1, dd_Smed_v6_28468_0_1, [Score=85.5, Expect=2e-17]} {RNA1509_30384} {RNA1310_34563.1} {RNA815_18979}
10. MligTC455_23621 323 6.72 Mlig455_039694, Mlig455_039749

Neo: -

Age: -

Region-enriched R2: 2.235/0.02499

2.751 0.953 - - 0.857 0.941 -

Mlig455_039694 {REF} {Length: 2054} {RNA1509_29694} {RNA1310_14789} {RNA815_12997}

Mlig455_039749 {REF} {Length: 1751} {RNA1509_29694} {RNA1310_14789, RNA1509_29694} {RNA1509_29694, RNA815_12997}
11. MligTC455_20026 3020 62.91 Mlig455_007228

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.365

Regeneration-depleted BL: -1.678
Regeneration-depleted R6: -1.165

GCLM 2.73 - 0.798 - 0.952 0.980 - Mlig455_007228 {REF} {Length: 2210} {Human: ENSG00000023909, GCLM, glutamate-cysteine ligase modifier subunit, [RH, Score=120, Expect=4e-32]} {Mouse: ENSMUSG00000028124, Gclm, glutamate-cysteine ligase, modifier subunit, [RH, Score=121, Expect=1e-32]} {Dmel: FBgn0046114, Gclm, Glutamate-cysteine ligase modifier subunit, [RH, Score=80.5, Expect=2e-17]} {Celegans: WBGene00017084, E01A2.1, [RH, Score=80.5, Expect=1e-17]} {Smed: dd_Smed_v6_487_0_1, dd_Smed_v6_487_0_1, [Score=105, Expect=4e-27]} {RNA1509_2089} {RNA1310_10444.1, RNA1509_2089} {RNA1509_2089, RNA815_4215}
12. MligTC455_54052 326 6.79 Mlig455_003203

Neo: -

Age: Down-Down-Down

Region-enriched R2: 3.038/0.00157

ETHE1 2.699 - 0.803 - 0.968 0.928 - Mlig455_003203 {REF} {Length: 1391} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=52.2]} {Human: ENSG00000105755, ETHE1, ETHE1, persulfide dioxygenase, [Score=304, Expect=9e-105]} {Mouse: ENSMUSG00000064254, Ethe1, ethylmalonic encephalopathy 1, [RH, Score=306, Expect=8e-106]} {Dmel: FBgn0050022, CG30022, [RH, Score=306, Expect=1e-105]} {Celegans: WBGene00007886, ethe-1, ETHE1 (Human ETHylmalonic Encephalopathy) homolog, [RH, Score=282, Expect=9e-97]} {Smed: dd_Smed_v6_944_0_1, dd_Smed_v6_944_0_1, [RH, Score=313, Expect=5e-109]} {RNA1509_6544} {RNA1310_29246} {RNA815_15142}
13. MligTC455_25458 4684 97.58 Mlig455_050151

Neo: -

Age: logFC(26M/2M)=0.292

URGCP 2.681 - 0.794 - 0.982 0.905 - Mlig455_050151 {REF} {Length: 9696} {Pfam: 50S ribosome-binding GTPase [PF01926.25, score=19.3]} {Human: ENSG00000106608, URGCP, upregulator of cell proliferation, [Score=162, Expect=1e-39]} {Mouse: ENSMUSG00000045868, Gvin1, GTPase, very large interferon inducible 1, [Score=420, Expect=8e-118]; ENSMUSG00000078606, Gm4070, predicted gene 4070, [Score=419, Expect=1e-117]} {RNA1509_12379, RNA1509_52869, RNA1509_56156, RNA1509_6781} {RNA1310_204.1, RNA1509_12379, RNA1509_52869, RNA1509_56156, RNA1509_6781} {RNA1509_12379, RNA1509_52869, RNA1509_56156, RNA1509_6781, RNA815_119.1}
14. MligTC455_32685 505 10.53 Mlig455_057075

Neo: -

Age: Up-Down-Up

2.669 0.896 - 0.821 - 0.952 - Mlig455_057075 {REF} {Length: 7466} {Pfam: REJ domain [PF02010.17, score=62.8]} {RNA1509_14190, RNA1509_21224, RNA1509_37446, RNA1509_40150} {RNA1310_402.1, RNA1509_14190, RNA1509_21224, RNA1509_37446, RNA1509_40150} {RNA1509_14190, RNA1509_21224, RNA1509_37446, RNA1509_40150, RNA815_93.1}
15. MligTC455_26585 173 3.61 Mlig455_061024

Neo: -

Age: -

2.666 0.816 - - - 0.983 0.867 Mlig455_061024 {REF} {Length: 2825} {RNA1509_19437} {RNA1310_38787} {RNA815_16416}
16. MligTC455_26015 1794 37.37 Mlig455_009233

Neo: -

Age: -

NR1I2 2.638 - 0.747 - 0.939 0.952 - Mlig455_009233 {REF} {Length: 2115} {TRANSSPLICED} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=60.8]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=82.4, Expect=2e-16]; ENSG00000143257, NR1I3, nuclear receptor subfamily 1 group I member 3, [Score=79.7, Expect=1e-15]} {Mouse: ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=80.1, Expect=9e-16]; ENSMUSG00000005677, Nr1i3, nuclear receptor subfamily 1, group I, member 3, [Score=79.7, Expect=7e-16]} {Dmel: FBgn0015240, Hr96, Hormone receptor-like in 96, [Score=82.4, Expect=2e-16]} {Celegans: WBGene00003638, nhr-48, Nuclear hormone receptor family member nhr-48, [Score=88.6, Expect=2e-18]} {Smed: dd_Smed_v6_14067_0_2, dd_Smed_v6_14067_0_2, [RH, Score=90.9, Expect=3e-19]} {RNA1509_45292, RNA1509_9871} {RNA1310_7620, RNA1509_45292} {RNA1509_45292, RNA815_3672.1}
17. MligTC455_41580 574 11.95 Mlig455_001194

Neo: -

Age: -

RBPMS 2.622 0.725 - - - 0.960 0.937 Mlig455_001194 {REF} {Length: 2007} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=63.4]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=23.1]} {Human: ENSG00000157110, RBPMS, RNA binding protein, mRNA processing factor, [RH, Score=135, Expect=2e-38]; ENSG00000166831, RBPMS2, RNA binding protein, mRNA processing factor 2, [RH, Score=134, Expect=1e-37]} {Mouse: ENSMUSG00000032387, Rbpms2, RNA binding protein with multiple splicing 2, [RH, Score=138, Expect=2e-39]; ENSMUSG00000031586, Rbpms, RNA binding protein gene with multiple splicing, [RH, Score=133, Expect=1e-37]} {Dmel: FBgn0263995, cpo, couch potato, [RH, Score=203, Expect=1e-59]} {Celegans: WBGene00003172, mec-8, Mec-8 protein, [RH, Score=144, Expect=5e-41]} {Smed: dd_Smed_v6_4296_0_3, dd_Smed_v6_4296_0_3, [RH, Score=161, Expect=2e-47]} {RNA1509_12950} {RNA1310_3819.2} {RNA815_19117.1}
18. MligTC455_33156 242 5.04 Mlig455_009077

Neo: -

Age: -

2.615 - - - 0.960 0.943 0.712 Mlig455_009077 {REF} {Length: 1532} {RNA1509_51204} {RNA1310_20216} {RNA815_16273.1}
19. MligTC455_48558 141 2.94 Mlig455_046385

Neo: -

Age: -

2.61 - - - 0.947 0.953 0.710 Mlig455_046385 {REF} {Length: 1458} {RNA1310_43065} {RNA815_11099}
20. MligTC455_33158 236 4.92 Mlig455_058103

Neo: -

Age: -

2.6 - - - 0.953 0.943 0.704 Mlig455_058103 {REF} {Length: 2616} {RNA1509_51204} {RNA1310_18006.1} {RNA815_6624}
21. MligTC455_19085 95 1.98 Mlig455_021540

Neo: -

Age: -

2.595 - - - 0.847 0.986 0.762 Mlig455_021540 {REF} {Length: 2045} {RNA1509_39251} {RNA1310_9860} {RNA815_3403}
22. MligTC455_42798 138 2.86 Mlig455_005345, Mlig455_005460

Neo: -

Age: logFC(26M/2M)=0.617

CLEC3A 2.59 - - 0.912 - 0.955 0.723

Mlig455_005345 {REF} {Length: 1469} {Pfam: Lectin C-type domain [PF00059.23, score=22.7]} {RNA1509_35720} {RNA1310_2191.3} {RNA815_1425.1}

Mlig455_005460 {REF} {Length: 722} {Pfam: Lectin C-type domain [PF00059.23, score=25.6]} {Human: ENSG00000166509, CLEC3A, C-type lectin domain family 3 member A, [Score=47.8, Expect=3e-06]} {RNA1509_35720} {RNA1310_2191.3} {RNA815_1425.1}
23. MligTC455_37894 129 2.7 Mlig455_070642

Neo: -

Age: Down-Up-Up

Region-enriched R7: 2.704/0.01368
Region-enriched R2: 2.685/0.01546

2.586 0.840 - - 0.770 0.976 - Mlig455_070642 {REF} {Length: 1246} {TRANSSPLICED} {Pfam: WSC domain [PF01822.21, score=46.7]} {RNA1310_35396.1} {RNA815_31795}
24. MligTC455_13095 40 0.82 Mlig455_036239

Neo: -

Age: -

2.583 0.877 - - - 0.989 0.717 Mlig455_036239 {REF} {Length: 2786} {RNA1509_41201} {RNA1310_51044} {RNA815_51130}
25. MligTC455_49334 86 1.78 Mlig455_037751

Neo: -

Age: -

2.574 0.865 - 0.725 - 0.984 - Mlig455_037751 {REF} {Length: 708} {RNA1509_25826} {RNA1310_47741} {RNA815_23874}
26. MligTC455_19337 1925 40.11 Mlig455_019013, Mlig455_055690

Neo: -

Age: -

FAT4 2.571 - - - 0.780 0.972 0.819

Mlig455_019013 {REF} {Length: 5843} {Pfam: Cadherin domain [PF00028.19, score=416.2]; Cadherin-like [PF16184.7, score=51.1]; Cadherin-like [PF08266.14, score=37.4]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=337, Expect=8e-93]; ENSG00000107736, CDH23, cadherin related 23, [Score=323, Expect=3e-88]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=340, Expect=7e-94]} {Dmel: FBgn0037963, Cad87A, Cadherin 87A, [RH, Score=565, Expect=1e-169]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=224, Expect=2e-58]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=285, Expect=1e-77]} {RNA1509_10894, RNA1509_28143} {RNA1310_769, RNA1509_10894, RNA1509_28143} {RNA1509_10894, RNA1509_28143, RNA815_221.1}

Mlig455_055690 {REF} {Length: 5861} {Pfam: Cadherin domain [PF00028.19, score=416.3]; Cadherin-like [PF16184.7, score=51.2]; Cadherin-like [PF08266.14, score=37.1]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=339, Expect=2e-93]; ENSG00000107736, CDH23, cadherin related 23, [Score=328, Expect=8e-90]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=345, Expect=3e-95]} {Dmel: FBgn0037963, Cad87A, Cadherin 87A, [RH, Score=561, Expect=2e-168]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=221, Expect=1e-57]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=278, Expect=3e-75]} {RNA1509_28056, RNA1509_38617, RNA1509_4473} {RNA1310_769, RNA1509_28056, RNA1509_38617, RNA1509_4473} {RNA1509_28056, RNA1509_38617, RNA1509_4473, RNA815_221.1}
27. MligTC455_36730 165 3.44 Mlig455_056961

Neo: -

Age: Up-Down-Down

2.571 - - 0.894 - 0.962 0.715 Mlig455_056961 {REF} {Length: 4865} {Pfam: Lipoma HMGIC fusion partner-like protein [PF10242.11, score=57.3]} {RNA1310_49374} {RNA815_39552}
28. MligTC455_41608 65 1.36 Mlig455_039948

Neo: -

Age: Down-Up-Down

2.544 0.888 - - - 0.951 0.705 Mlig455_039948 {REF} {Length: 4005} {RNA1310_25006} {RNA815_53385}
29. MligTC455_41891 8767 182.64 Mlig455_000086

Neo: -

Age: -

Regeneration-downregulated BL: -1.617

Regeneration-depleted BL: -1.617

TTPAL 2.537 - - - 0.953 0.845 0.739 Mlig455_000086 {REF} {Length: 1586} {Pfam: CRAL/TRIO domain [PF00650.22, score=66.8]} {Human: ENSG00000124120, TTPAL, alpha tocopherol transfer protein like, [Score=117, Expect=1e-29]} {Mouse: ENSMUSG00000017679, Ttpal, tocopherol (alpha) transfer protein-like, [Score=115, Expect=5e-29]} {Dmel: FBgn0053966, CG33966, [Score=117, Expect=2e-30]} {Celegans: WBGene00011962, T23G5.2, CRAL-TRIO domain-containing protein T23G5.2, [Score=50.1, Expect=1e-06]} {Smed: dd_Smed_v6_2760_0_1, dd_Smed_v6_2760_0_1, [Score=222, Expect=2e-70]} {RNA1509_3153, RNA1509_43327, RNA1509_46435, RNA1509_896} {RNA1310_28769.1, RNA1509_3153, RNA1509_43327, RNA1509_46435, RNA1509_896} {RNA1509_3153, RNA1509_43327, RNA1509_46435, RNA1509_896, RNA815_2361}
30. MligTC455_40727 251 5.23 Mlig455_035865, Mlig455_035903

Neo: -

Age: logFC(26M/2M)=-0.563

2.536 0.797 - - - 0.987 0.752

Mlig455_035865 {REF} {Length: 1198} {Pfam: Linker region of enhancer of mRNA-decapping protein 3 [PF16598.7, score=19.4]} {RNA1310_40952} {RNA815_53592}

Mlig455_035903 {REF} {Length: 1199} {Pfam: Linker region of enhancer of mRNA-decapping protein 3 [PF16598.7, score=19.4]} {RNA1310_40952} {RNA815_53592}
31. MligTC455_47244 216 4.49 Mlig455_016130

Neo: -

Age: -

Region-enriched R2: 3.391/0.02151
Region-enriched R6: 2.922/0.03099

2.528 0.847 - - - 0.953 0.728 Mlig455_016130 {REF} {Length: 3312} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=27.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=20.5]} {Smed: dd_Smed_v6_24733_0_1, dd_Smed_v6_24733_0_1, [RH, Score=231, Expect=1e-71]} {RNA1509_41111} {RNA1310_18481.1} {RNA815_10445}
32. MligTC455_16005 97 2.02 Mlig455_018551, Mlig455_019423, Mlig455_058389

Neo: -

Age: -

2.527 - - 0.850 - 0.962 0.715

Mlig455_018551 {REF} {Length: 3430} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=24.1]} {RNA1509_42342} {RNA1310_4557} {RNA815_16034.1}

Mlig455_019423 {REF} {Length: 2545} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=24.1]} {RNA1509_42342} {RNA1310_4557} {RNA815_16034.1}

Mlig455_058389 {REF} {Length: 3494} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=24.1]} {RNA1509_42342} {RNA1310_4557} {RNA815_16034.1}
33. MligTC455_40845 589 12.26 Mlig455_026868

Neo: -

Age: logFC(26M/2M)=-0.459

Region-enriched R2: 1.780/0.00896

KCNMA1 2.51 0.747 - - - 0.955 0.808 Mlig455_026868 {REF} {Length: 4484} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=87.9]; Ion channel [PF07885.18, score=46.7]; Ion transport protein [PF00520.33, score=25.3]; TrkA-N domain [PF02254.20, score=24.9]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=469, Expect=2e-145]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=468, Expect=1e-145]} {Dmel: FBgn0003429, slo, slowpoke, [Score=483, Expect=2e-151]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=450, Expect=2e-139]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=466, Expect=1e-145]} {RNA1509_12064} {RNA1310_2763} {RNA815_792.1}
34. MligTC455_15662 187 3.89 Mlig455_030386

Neo: -

Age: -

Region-enriched R2: 3.832/0.01388

Regeneration-upregulated BL: 4.705

Regeneration-enriched BL: 4.705

NR2E1 2.506 0.807 - - - 0.955 0.744 Mlig455_030386 {REF} {Length: 2439} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=98.4]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=73.9]} {Human: ENSG00000112333, NR2E1, nuclear receptor subfamily 2 group E member 1, [RH, Score=190, Expect=8e-54]} {Mouse: ENSMUSG00000019803, Nr2e1, nuclear receptor subfamily 2, group E, member 1, [Score=190, Expect=2e-54]} {Dmel: FBgn0003720, tll, tailless, [RH, Score=205, Expect=3e-59]} {Celegans: WBGene00003657, nhr-67, Nuclear hormone receptor family member nhr-67, [RH, Score=194, Expect=1e-55]} {Smed: dd_Smed_v6_21347_0_1, dd_Smed_v6_21347_0_1, [RH, Score=189, Expect=4e-54]} {RNA1509_39776} {RNA1310_21550} {RNA815_27099.1}
35. MligTC455_40152 71 1.48 Mlig455_044652

Neo: -

Age: -

CALML3 2.493 0.779 - - - 0.953 0.761 Mlig455_044652 {REF} {Length: 973} {Pfam: EF hand [PF00036.34, score=85.2]; EF-hand domain pair [PF13499.8, score=84.3]; EF-hand domain [PF13405.8, score=70.9]; EF-hand domain pair [PF13833.8, score=61.0]; EF hand [PF13202.8, score=51.9]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=36.6]; EF-hand domain [PF14658.8, score=21.5]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=94.0, Expect=2e-24]} {Mouse: ENSMUSG00000033765, Calm4, calmodulin 4, [Score=86.3, Expect=1e-21]} {Dmel: FBgn0033238, azot, ahuizotl, [Score=76.3, Expect=7e-18]} {Celegans: WBGene00006583, tnc-2, Troponin C, isoform 2, [Score=63.5, Expect=4e-13]} {Smed: dd_Smed_v6_11942_0_1, dd_Smed_v6_11942_0_1, [Score=96.3, Expect=1e-25]} {RNA1310_41156} {RNA815_20058}
36. MligTC455_46708 362 7.53 Mlig455_045334

Neo: -

Age: -

Region-enriched R2: 2.783/0.01800

2.489 0.740 - - - 0.973 0.776 Mlig455_045334 {REF} {Length: 1243} {RNA1509_51601} {RNA1310_43115.2, RNA1509_51601} {RNA1509_51601, RNA815_21402.1}
37. MligTC455_00873 4331 90.22 Mlig455_021477

Neo: -

Age: Down-Down-Up

2.488 - - - 0.825 0.952 0.711 Mlig455_021477 {REF} {Length: 796} {RNA1509_1530} {RNA1310_43551.1} {RNA815_23356}
38. MligTC455_43225 1135 23.64 Mlig455_028905

Neo: -

Age: Down-Up-Up

GRM3 2.476 - - - 0.759 0.980 0.737 Mlig455_028905 {REF} {Length: 3858} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=107.1]; Receptor family ligand binding region [PF01094.30, score=53.1]} {Human: ENSG00000198822, GRM3, glutamate metabotropic receptor 3, [Score=121, Expect=1e-27]} {Mouse: ENSMUSG00000003974, Grm3, glutamate receptor, metabotropic 3, [Score=122, Expect=8e-28]} {Dmel: FBgn0050361, mtt, mangetout, [Score=131, Expect=9e-31]} {Celegans: WBGene00003233, mgl-2, Metabotropic GLutamate receptor family, [Score=64.3, Expect=3e-10]} {Smed: dd_Smed_v6_32826_0_1, dd_Smed_v6_32826_0_1, [Score=66.6, Expect=4e-11]} {RNA1509_36690, RNA1509_57807, RNA1509_8888} {RNA1310_2635, RNA1509_36690, RNA1509_57807, RNA1509_8888} {RNA1509_36690, RNA1509_57807, RNA1509_8888, RNA815_904}
39. MligTC455_33807 5328 111 Mlig455_009549

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.374

MOXD1 2.468 - - - 0.706 0.952 0.810 Mlig455_009549 {REF} {Length: 2314} {TRANSSPLICED} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=92.6]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=67.9]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=120, Expect=4e-28]; ENSG00000123454, DBH, dopamine beta-hydroxylase, [Score=117, Expect=6e-27]} {Mouse: ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=135, Expect=4e-33]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=127, Expect=1e-30]} {Celegans: WBGene00006541, tbh-1, Tyramine beta-hydroxylase, [Score=137, Expect=3e-34]} {Smed: dd_Smed_v6_42610_0_1, dd_Smed_v6_42610_0_1, [Score=117, Expect=1e-28]} {RNA1509_127, RNA1509_16513, RNA1509_19891, RNA1509_42226} {RNA1310_10830.1, RNA1509_127, RNA1509_16513, RNA1509_19891, RNA1509_42226} {RNA1509_127, RNA1509_16513, RNA1509_19891, RNA1509_42226, RNA815_4383.2}
40. MligTC455_19042 3679 76.64 Mlig455_030661

Neo: -

Age: logFC(26M/2M)=0.480

Region-specific R2: 2.811

Region-enriched R2: 1.755/0.00003

CAV1 2.464 - - - 0.721 0.970 0.773 Mlig455_030661 {REF} {Length: 1257} {Pfam: Caveolin [PF01146.19, score=124.8]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=105, Expect=2e-29]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=105, Expect=2e-29]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=81.6, Expect=8e-20]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=144, Expect=1e-45]} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1310_31540, RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522, RNA815_14585}
41. MligTC455_44301 1697 35.36 Mlig455_000545

Neo: -

Age: -

2.439 - 0.760 - 0.708 0.971 - Mlig455_000545 {REF} {Length: 1706} {TRANSSPLICED} {Smed: dd_Smed_v6_6108_0_1, dd_Smed_v6_6108_0_1, [RH, Score=190, Expect=9e-63]} {RNA1509_16536, RNA1509_27118, RNA1509_9934} {RNA1310_30744, RNA1509_16536, RNA1509_27118, RNA1509_9934} {RNA1509_16536, RNA1509_27118, RNA1509_9934, RNA815_13864}
42. MligTC455_33599 990 20.63 Mlig455_059026

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.377

CPLANE1 2.436 - 0.750 - 0.730 0.956 - Mlig455_059026 {REF} {Length: 10323} {TRANSSPLICED} {Pfam: Joubert syndrome-associated [PF15392.8, score=19.1]} {Human: ENSG00000197603, CPLANE1, ciliogenesis and planar polarity effector 1, [RH, Score=136, Expect=6e-31]} {Mouse: ENSMUSG00000039801, Cplane1, ciliogenesis and planar polarity effector 1, [RH, Score=138, Expect=1e-31]} {RNA1509_1312, RNA1509_13367, RNA1509_16834, RNA1509_24724} {RNA1310_343.1, RNA1509_1312, RNA1509_13367, RNA1509_16834, RNA1509_24724} {RNA1509_1312, RNA1509_13367, RNA1509_16834, RNA1509_24724, RNA815_482.1}
43. MligTC455_21523 317 6.61 Mlig455_029394

Neo: -

Age: -

Region-enriched R6: 2.246/0.01608

Regeneration-downregulated R6: -3.517

Regeneration-depleted R6: -3.517

MYL4 2.435 - - - 0.723 0.965 0.747 Mlig455_029394 {REF} {Length: 861} {Pfam: EF-hand domain pair [PF13499.8, score=40.0]; EF hand [PF00036.34, score=25.2]; EF-hand domain pair [PF13833.8, score=24.8]; EF-hand domain [PF13405.8, score=22.4]} {Human: ENSG00000198336, MYL4, myosin light chain 4, [Score=57.4, Expect=7e-10]; ENSG00000160808, MYL3, myosin light chain 3, [Score=55.5, Expect=4e-09]} {Mouse: ENSMUSG00000059741, Myl3, myosin, light polypeptide 3, [Score=57.4, Expect=5e-10]; ENSMUSG00000061086, Myl4, myosin, light polypeptide 4, [Score=56.6, Expect=7e-10]} {Dmel: FBgn0004687, Mlc-c, Myosin light chain cytoplasmic, [Score=70.1, Expect=3e-15]} {Celegans: WBGene00011734, mlc-5, Myosin-2 essential light chain, [Score=61.6, Expect=3e-12]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=48.5, Expect=6e-07]} {RNA1509_43205} {RNA1310_45370, RNA1509_43205} {RNA1509_43205, RNA815_24120.1}
44. MligTC455_51032 968 20.16 Mlig455_048104

Neo: -

Age: -

Region-enriched R8: 2.057/0.00119

CAV1 2.429 - - - 0.976 0.735 0.718 Mlig455_048104 {REF} {Length: 1164} {Pfam: Caveolin [PF01146.19, score=119.2]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=107, Expect=7e-29]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=107, Expect=4e-29]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=81.6, Expect=6e-19]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=142, Expect=1e-43]} {RNA1509_58612} {RNA1310_36937.1} {RNA815_17384.1}
45. MligTC455_36507 1422 29.63 Mlig455_038156, Mlig455_038261

Neo: -

Age: logFC(26M/2M)=-0.241

DNAI2 2.427 0.707 - - - 0.963 0.757

Mlig455_038156 {REF} {Length: 2699} {TRANSSPLICED} {Human: ENSG00000171595, DNAI2, dynein axonemal intermediate chain 2, [Score=534, Expect=0.0]} {Mouse: ENSMUSG00000034706, Dnaic2, dynein, axonemal, intermediate chain 2, [Score=513, Expect=1e-178]} {Dmel: FBgn0036195, Dnai2, dynein, axonemal, intermediate chain 2, [Score=386, Expect=4e-129]} {Smed: dd_Smed_v6_2644_0_1, dd_Smed_v6_2644_0_1, [Score=612, Expect=0.0]} {RNA1509_8245} {RNA1310_9583.1} {RNA815_3264}

Mlig455_038261 {REF} {Length: 2387} {TRANSSPLICED} {Human: ENSG00000171595, DNAI2, dynein axonemal intermediate chain 2, [RH, Score=756, Expect=0.0]} {Mouse: ENSMUSG00000034706, Dnaic2, dynein, axonemal, intermediate chain 2, [RH, Score=740, Expect=0.0]} {Dmel: FBgn0036195, Dnai2, dynein, axonemal, intermediate chain 2, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_2644_0_1, dd_Smed_v6_2644_0_1, [RH, Score=867, Expect=0.0]} {RNA1509_8245} {RNA1310_9583.1} {RNA815_3264}
46. MligTC455_47414 197 4.09 Mlig455_039028

Neo: -

Age: logFC(26M/2M)=-0.558

2.391 0.722 - - - 0.964 0.705 Mlig455_039028 {REF} {Length: 2399} {Pfam: Integrase core domain [PF00665.28, score=45.7]} {Smed: dd_Smed_v6_94688_0_1, dd_Smed_v6_94688_0_1, [Score=58.5, Expect=4e-11]} {RNA1509_33291} {RNA1310_1940.1} {RNA815_1595}
47. MligTC455_20027 1159 24.14 Mlig455_007217, Mlig455_007451

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.831

GCLM 1.914 - - - 0.965 0.949 -

Mlig455_007217 {REF} {Length: 2261} {Human: ENSG00000023909, GCLM, glutamate-cysteine ligase modifier subunit, [RH, Score=120, Expect=7e-32]} {Mouse: ENSMUSG00000028124, Gclm, glutamate-cysteine ligase, modifier subunit, [RH, Score=120, Expect=3e-32]} {Dmel: FBgn0046114, Gclm, Glutamate-cysteine ligase modifier subunit, [Score=78.6, Expect=9e-17]} {Celegans: WBGene00017084, E01A2.1, [RH, Score=78.6, Expect=8e-17]} {Smed: dd_Smed_v6_487_0_1, dd_Smed_v6_487_0_1, [Score=107, Expect=9e-28]} {RNA1509_2089} {RNA1310_10444.1} {RNA815_4215}

Mlig455_007451 {REF} {Length: 2259} {Human: ENSG00000023909, GCLM, glutamate-cysteine ligase modifier subunit, [RH, Score=120, Expect=7e-32]} {Mouse: ENSMUSG00000028124, Gclm, glutamate-cysteine ligase, modifier subunit, [RH, Score=120, Expect=3e-32]} {Dmel: FBgn0046114, Gclm, Glutamate-cysteine ligase modifier subunit, [Score=78.6, Expect=9e-17]} {Celegans: WBGene00017084, E01A2.1, [RH, Score=78.6, Expect=8e-17]} {Smed: dd_Smed_v6_487_0_1, dd_Smed_v6_487_0_1, [Score=107, Expect=9e-28]} {RNA1509_2089} {RNA1310_10444.1} {RNA815_4215}
48. MligTC455_35943 122 2.55 Mlig455_062123

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.634

FEZF2 1.889 - - 0.904 - 0.985 - Mlig455_062123 {REF} {Length: 3163} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=87.7]; Zinc-finger double domain [PF13465.8, score=71.3]; C2H2-type zinc finger [PF13894.8, score=56.0]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=25.4]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=23.1]; C2H2-type zinc finger [PF13912.8, score=21.6]} {Human: ENSG00000153266, FEZF2, FEZ family zinc finger 2, [RH, Score=337, Expect=3e-107]; ENSG00000128610, FEZF1, FEZ family zinc finger 1, [RH, Score=330, Expect=6e-105]} {Mouse: ENSMUSG00000021743, Fezf2, Fez family zinc finger 2, [RH, Score=341, Expect=7e-109]; ENSMUSG00000029697, Fezf1, Fez family zinc finger 1, [RH, Score=330, Expect=1e-104]} {Dmel: FBgn0031375, erm, earmuff, [RH, Score=343, Expect=2e-107]} {Celegans: WBGene00012639, fezf-1, FEZ Family zinc finger protein, [RH, Score=293, Expect=5e-94]} {Smed: dd_Smed_v6_26394_0_1, dd_Smed_v6_26394_0_1, [RH, Score=287, Expect=9e-92]} {RNA1310_14572} {RNA815_32467}
49. MligTC455_46858 43 0.89 Mlig455_027443

Neo: -

Age: Up-Down-Up

TJP1 1.889 - - - 0.972 0.917 - Mlig455_027443 {REF} {Length: 3643} {Pfam: PDZ domain [PF00595.26, score=44.0]; PDZ domain [PF17820.3, score=28.6]; ZU5 domain [PF00791.22, score=27.8]; Guanylate kinase [PF00625.23, score=22.9]; PDZ domain [PF13180.8, score=20.5]} {Human: ENSG00000104067, TJP1, tight junction protein 1, [Score=165, Expect=7e-42]; ENSG00000277401, TJP1, tight junction protein 1, [Score=165, Expect=7e-42]; ENSG00000119139, TJP2, tight junction protein 2, [Score=157, Expect=3e-40]} {Mouse: ENSMUSG00000030516, Tjp1, tight junction protein 1, [Score=167, Expect=1e-42]} {Dmel: FBgn0262614, pyd, polychaetoid, [Score=184, Expect=3e-48]} {Celegans: WBGene00013683, zoo-1, ZO-1 (Zonula Occludens tight junctional protein) Ortholog, [Score=157, Expect=1e-39]} {Smed: dd_Smed_v6_7374_0_1, dd_Smed_v6_7374_0_1, [Score=51.2, Expect=2e-06]} {RNA1509_35829} {RNA1310_1784} {RNA815_1919}
50. MligTC455_45492 58 1.21 Mlig455_034276

Neo: -

Age: -

1.885 - - 0.916 - 0.969 - Mlig455_034276 {REF} {Length: 2718} {RNA1509_59550} {RNA1310_17865.1} {RNA815_34375}
51. MligTC455_52528 145 3.03 Mlig455_025895

Neo: -

Age: logFC(26M/2M)=-0.670

FLVCR2 1.88 - - - 0.952 0.928 - Mlig455_025895 {REF} {Length: 2218} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=82.0]; Sugar (and other) transporter [PF00083.26, score=18.7]} {Human: ENSG00000119686, FLVCR2, feline leukemia virus subgroup C cellular receptor family member 2, [RH, Score=364, Expect=4e-119]} {Mouse: ENSMUSG00000034258, Flvcr2, feline leukemia virus subgroup C cellular receptor 2, [RH, Score=368, Expect=2e-120]} {Dmel: FBgn0033196, CG1358, [RH, Score=350, Expect=1e-114]} {Celegans: WBGene00015632, C09D4.1, Uncharacterized MFS-type transporter C09D4.1, [RH, Score=358, Expect=2e-116]} {Smed: dd_Smed_v6_7578_0_1, dd_Smed_v6_7578_0_1, [Score=335, Expect=3e-109]} {RNA1509_31725} {RNA1310_8852.1, RNA1509_31725} {RNA1509_31725, RNA815_14234}
52. MligTC455_46654 2137 44.52 Mlig455_051380

Neo: -

Age: Down-Up-Down

EPS8L2 1.87 - 0.903 - - 0.967 - Mlig455_051380 {REF} {Length: 3696} {TRANSSPLICED} {Pfam: Phosphotyrosine-binding domain [PF08416.15, score=42.1]; SH3 domain [PF00018.30, score=23.9]} {Human: ENSG00000177106, EPS8L2, EPS8 like 2, [RH, Score=158, Expect=5e-40]; ENSG00000151491, EPS8, epidermal growth factor receptor pathway substrate 8, [RH, Score=153, Expect=5e-38]} {Mouse: ENSMUSG00000015766, Eps8, epidermal growth factor receptor pathway substrate 8, [RH, Score=159, Expect=6e-40]; ENSMUSG00000025504, Eps8l2, EPS8-like 2, [RH, Score=154, Expect=8e-39]} {Dmel: FBgn0029095, aru, arouser, [RH, Score=161, Expect=4e-41]} {Celegans: WBGene00001330, eps-8, EPS (Human endocytosis) related; Epidermal growth factor receptor pathway substrate 8 splice variant A, [RH, Score=215, Expect=7e-60]} {Smed: dd_Smed_v6_4256_0_1, dd_Smed_v6_4256_0_1, [RH, Score=79.0, Expect=4e-15]} {RNA1509_4398} {RNA1310_3514} {RNA815_6294}
53. MligTC455_17997 249 5.18 Mlig455_031355

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.965

Regeneration-downregulated R6: -3.161

Regeneration-depleted R6: -3.161

ANK2 1.864 - - 0.889 - 0.975 - Mlig455_031355 {REF} {Length: 3392} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=225.1]; Ankyrin repeats (many copies) [PF13637.8, score=151.6]; Ankyrin repeat [PF00023.32, score=151.0]; Ankyrin repeat [PF13606.8, score=136.9]; Ankyrin repeats (many copies) [PF13857.8, score=128.5]; Caspase domain [PF00656.24, score=64.0]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=117, Expect=3e-26]; ENSG00000151150, ANK3, ankyrin 3, [Score=113, Expect=7e-25]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=127, Expect=2e-29]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=130, Expect=1e-30]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=120, Expect=1e-27]} {Smed: dd_Smed_v6_2072_0_24, dd_Smed_v6_2072_0_24, [Score=115, Expect=5e-26]} {RNA1509_59314, RNA1509_6998} {RNA1310_4219, RNA1509_59314, RNA1509_6998} {RNA1509_59314, RNA1509_6998, RNA815_1303}
54. MligTC455_33157 281 5.86 Mlig455_009092

Neo: -

Age: -

1.861 - - - 0.963 0.898 - Mlig455_009092 {REF} {Length: 5302} {RNA1509_51204} {RNA1310_20216} {RNA815_6624}
55. MligTC455_40846 835 17.39 Mlig455_030827, Mlig455_047790

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.236

KCNMA1 1.859 - - - 0.898 0.961 -

Mlig455_030827 {REF} {Length: 3985} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=88.0]; Ion channel [PF07885.18, score=46.9]; Ion transport protein [PF00520.33, score=25.2]; TrkA-N domain [PF02254.20, score=24.3]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=482, Expect=1e-151]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=481, Expect=3e-151]} {Dmel: FBgn0003429, slo, slowpoke, [Score=339, Expect=4e-99]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=459, Expect=8e-144]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=479, Expect=1e-151]} {RNA1509_12064, RNA1509_38332} {RNA1310_2763, RNA1509_38332} {RNA1509_38332, RNA815_792.1}

Mlig455_047790 {REF} {Length: 4417} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=87.7]; Ion channel [PF07885.18, score=46.7]; TrkA-N domain [PF02254.20, score=23.6]; Ion transport protein [PF00520.33, score=21.9]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=479, Expect=1e-148]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=478, Expect=7e-149]} {Dmel: FBgn0003429, slo, slowpoke, [Score=340, Expect=2e-98]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=455, Expect=1e-140]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=475, Expect=3e-148]} {RNA1509_38332, RNA1509_48456} {RNA1310_2763, RNA1509_48456} {RNA1509_48456, RNA815_792.1}
56. MligTC455_46438 147 3.07 Mlig455_021783

Neo: -

Age: Up-Down-Down

1.857 0.890 - - - 0.967 - Mlig455_021783 {REF} {Length: 2899} {RNA1509_36156} {RNA1310_17582, RNA1509_36156} {RNA1509_36156, RNA815_32277}
57. MligTC455_48559 64 1.33 Mlig455_046411

Neo: -

Age: -

1.848 - - - 0.886 0.962 - Mlig455_046411 {REF} {Length: 1333} {TRANSSPLICED} {RNA1310_43065} {RNA815_11099}
58. MligTC455_11146 70 1.46 Mlig455_068743

Neo: -

Age: Down-Up-Down

C11orf65 1.846 0.896 - - - 0.950 - Mlig455_068743 {REF} {Length: 1750} {Human: ENSG00000166323, C11orf65, chromosome 11 open reading frame 65, [RH, Score=226, Expect=4e-72]} {Mouse: ENSMUSG00000005131, 4930550C14Rik, RIKEN cDNA 4930550C14 gene, [RH, Score=214, Expect=2e-67]} {Smed: dd_Smed_v6_13591_0_1, dd_Smed_v6_13591_0_1, [RH, Score=237, Expect=9e-77]} {RNA1310_22540.1} {RNA815_13464}
59. MligTC455_24940 3175 66.14 Mlig455_011276, Mlig455_011374

Neo: -

Age: Down-Up-Up

1.846 - - - - 0.985 0.861

Mlig455_011276 {REF} {Length: 3380} {Pfam: Reeler domain [PF02014.18, score=50.9]; Eukaryotic cytochrome b561 [PF03188.18, score=38.4]} {Celegans: WBGene00007339, C05D12.1, [Score=68.2, Expect=9e-12]} {Smed: dd_Smed_v6_13311_0_1, dd_Smed_v6_13311_0_1, [Score=155, Expect=4e-40]} {RNA1509_34604, RNA1509_36747, RNA1509_52003, RNA1509_58766} {RNA1310_16616, RNA1509_36747, RNA1509_52003, RNA1509_58766} {RNA1509_36747, RNA1509_52003, RNA1509_58766, RNA815_3087.1}

Mlig455_011374 {REF} {Length: 4099} {Pfam: Reeler domain [PF02014.18, score=51.0]; Eukaryotic cytochrome b561 [PF03188.18, score=38.1]} {Celegans: WBGene00007339, C05D12.1, [Score=68.2, Expect=8e-12]} {Smed: dd_Smed_v6_13311_0_1, dd_Smed_v6_13311_0_1, [Score=153, Expect=2e-39]} {RNA1509_25592, RNA1509_34604, RNA1509_41623, RNA1509_55699} {RNA1310_16616, RNA1509_25592, RNA1509_34604, RNA1509_41623, RNA1509_55699} {RNA1509_25592, RNA1509_34604, RNA1509_41623, RNA1509_55699, RNA815_3087.1}
60. MligTC455_41581 438 9.13 Mlig455_001354

Neo: -

Age: -

RBPMS 1.846 - - - - 0.958 0.888 Mlig455_001354 {REF} {Length: 2343} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=63.4]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=23.1]} {Human: ENSG00000157110, RBPMS, RNA binding protein, mRNA processing factor, [RH, Score=135, Expect=2e-38]; ENSG00000166831, RBPMS2, RNA binding protein, mRNA processing factor 2, [RH, Score=134, Expect=1e-37]} {Mouse: ENSMUSG00000032387, Rbpms2, RNA binding protein with multiple splicing 2, [RH, Score=138, Expect=2e-39]; ENSMUSG00000031586, Rbpms, RNA binding protein gene with multiple splicing, [RH, Score=133, Expect=1e-37]} {Dmel: FBgn0263995, cpo, couch potato, [RH, Score=203, Expect=1e-59]} {Celegans: WBGene00003172, mec-8, Mec-8 protein, [RH, Score=144, Expect=5e-41]} {Smed: dd_Smed_v6_4296_0_3, dd_Smed_v6_4296_0_3, [RH, Score=161, Expect=2e-47]} {RNA1509_12950} {RNA1310_3819.2} {RNA815_19117.1}
61. MligTC455_39515 27644 575.93 Mlig455_031388

Neo: -

Age: -

CAV3 1.842 - - - 0.887 0.955 - Mlig455_031388 {REF} {Length: 1882} {Pfam: Caveolin [PF01146.19, score=124.4]} {Human: ENSG00000182533, CAV3, caveolin 3, [Score=94.4, Expect=5e-25]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [RH, Score=92.4, Expect=2e-24]} {Celegans: WBGene00000302, cav-2, Caveolin-2, [RH, Score=73.9, Expect=2e-17]} {Smed: dd_Smed_v6_877_0_1, dd_Smed_v6_877_0_1, [RH, Score=127, Expect=1e-38]} {RNA1509_1284, RNA1509_15662, RNA1509_257} {RNA1310_50452, RNA1509_1284, RNA1509_15662, RNA1509_257} {RNA1509_1284, RNA1509_15662, RNA1509_257, RNA815_18477}
62. MligTC455_43663 88 1.83 Mlig455_070157

Neo: -

Age: Up-Down-Up

1.839 - - 0.849 - 0.990 - Mlig455_070157 {REF} {Length: 2611} {RNA1310_65373} {RNA815_37965}
63. MligTC455_04786 26 0.55 Mlig455_043817, Mlig455_047431

Neo: -

Age: -

1.838 0.849 - - - 0.989 -

Mlig455_043817 {REF} {Length: 319} {NoTransDecoderORF} {RNA1310_64690}

Mlig455_047431 {REF} {Length: 2194} {Pfam: Glycine rich protein [PF12810.9, score=25.3]} {RNA1509_16377} {RNA1310_33363.2} {RNA815_25152}
64. MligTC455_09903 33 0.68 Mlig455_051109

Neo: Irradiation

Age: Up-Down-Down

WNT5A 1.838 - - 0.868 - 0.970 - Mlig455_051109 {REF} {Length: 3244} {Pfam: wnt family [PF00110.21, score=260.2]} {Human: ENSG00000114251, WNT5A, Wnt family member 5A, [Score=247, Expect=1e-73]; ENSG00000111186, WNT5B, Wnt family member 5B, [Score=243, Expect=3e-72]} {Mouse: ENSMUSG00000021994, Wnt5a, wingless-type MMTV integration site family, member 5A, [Score=247, Expect=8e-74]; ENSMUSG00000030170, Wnt5b, wingless-type MMTV integration site family, member 5B, [Score=245, Expect=4e-73]} {Dmel: FBgn0010194, Wnt5, Wnt oncogene analog 5, [RH, Score=160, Expect=4e-40]} {Celegans: WBGene00000858, cwn-2, [Score=221, Expect=1e-64]} {Smed: dd_Smed_v6_15469_0_1, dd_Smed_v6_15469_0_1, [Score=243, Expect=9e-73]} {RNA1509_24293} {RNA1310_13535} {RNA815_8371}
65. MligTC455_50344 24 0.51 Mlig455_054355

Neo: -

Age: -

1.83 0.849 - - - 0.981 - Mlig455_054355 {REF} {Length: 1376} {RNA1310_56750}
66. MligTC455_16875 42 0.88 Mlig455_028243

Neo: -

Age: Up-Down-Down

KCNK16 1.828 0.838 - - - 0.990 - Mlig455_028243 {REF} {Length: 2676} {Pfam: Ion channel [PF07885.18, score=116.8]; Ion transport protein [PF00520.33, score=28.8]; Protein of unknown function (DUF3112) [PF11309.10, score=19.5]} {Human: ENSG00000095981, KCNK16, potassium two pore domain channel subfamily K member 16, [Score=97.8, Expect=5e-22]; ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [Score=97.4, Expect=2e-21]; ENSG00000100433, KCNK10, potassium two pore domain channel subfamily K member 10, [Score=94.4, Expect=6e-20]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=102, Expect=4e-23]; ENSMUSG00000023387, Kcnk16, potassium channel, subfamily K, member 16, [Score=98.2, Expect=2e-22]} {Dmel: FBgn0033257, sand, sandman, [Score=150, Expect=2e-40]} {Celegans: WBGene00010784, twk-48, TWiK family of potassium channels, [Score=162, Expect=5e-45]} {Smed: dd_Smed_v6_17586_0_1, dd_Smed_v6_17586_0_1, [Score=340, Expect=2e-113]} {RNA1509_39975} {RNA1310_18301.1, RNA1509_39975} {RNA1509_39975, RNA815_12440}
67. MligTC455_46216 1117 23.28 Mlig455_057440

Neo: -

Age: -

Region-enriched R7: 2.350/0.00017
Region-enriched R8: 2.312/0.00270

RBPMS2 1.827 - - - - 0.872 0.955 Mlig455_057440 {REF} {Length: 4543} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=53.4]} {Human: ENSG00000166831, RBPMS2, RNA binding protein, mRNA processing factor 2, [RH, Score=128, Expect=2e-35]} {Mouse: ENSMUSG00000031586, Rbpms, RNA binding protein gene with multiple splicing, [RH, Score=125, Expect=3e-35]} {Dmel: FBgn0263995, cpo, couch potato, [Score=164, Expect=7e-46]} {Celegans: WBGene00003172, mec-8, Mec-8 protein, [Score=124, Expect=4e-33]} {Smed: dd_Smed_v6_4296_0_4, dd_Smed_v6_4296_0_4, [Score=150, Expect=3e-43]} {RNA1509_30119} {RNA1310_16586.1} {RNA815_23894}
68. MligTC455_17237 20 0.42 Mlig455_045097

Neo: -

Age: -

1.824 0.845 - - - 0.979 - Mlig455_045097 {REF} {Length: 1126} {NoTransDecoderORF} {RNA1310_82726} {RNA815_53241.1}
69. MligTC455_43581 177 3.68 Mlig455_042725, Mlig455_042827, Mlig455_063146

Neo: -

Age: Up-Down-Down

GRIA2 1.823 0.847 - - - 0.976 -

Mlig455_042725 {REF} {Length: 3074} {Pfam: Ligand-gated ion channel [PF00060.28, score=104.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.7]; Receptor family ligand binding region [PF01094.30, score=33.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=153, Expect=1e-37]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=149, Expect=2e-36]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=147, Expect=7e-36]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=152, Expect=2e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=148, Expect=3e-36]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=147, Expect=8e-36]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=2e-35]} {Dmel: FBgn0038837, CG3822, [Score=140, Expect=5e-34]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=253, Expect=2e-76]} {RNA1310_25150} {RNA815_13942}

Mlig455_042827 {REF} {Length: 2869} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.9]; Receptor family ligand binding region [PF01094.30, score=49.8]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.3]; Iron-containing alcohol dehydrogenase [PF13685.8, score=18.6]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=125, Expect=6e-29]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=122, Expect=5e-28]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=121, Expect=7e-28]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=120, Expect=2e-27]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=125, Expect=5e-29]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=122, Expect=4e-28]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=121, Expect=1e-27]; ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=120, Expect=1e-27]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=119, Expect=3e-27]} {Dmel: FBgn0039927, CG11155, [Score=127, Expect=7e-30]} {Celegans: WBGene00001612, glr-1, Glutamate receptor 1, [Score=103, Expect=1e-22]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=217, Expect=2e-63]} {RNA1310_25150} {RNA815_13942}

Mlig455_063146 {REF} {Length: 2444} {Pfam: Receptor family ligand binding region [PF01094.30, score=35.8]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=82.4, Expect=1e-16]} {RNA1310_25150} {RNA815_13999}
70. MligTC455_18499 24 0.5 Mlig455_012628

Neo: -

Age: -

1.821 0.848 - - - 0.973 - Mlig455_012628 {REF} {Length: 1340} {Smed: dd_Smed_v6_500_0_1, dd_Smed_v6_500_0_1, [Score=60.5, Expect=1e-10]} {RNA1310_107419} {RNA815_46554}
71. MligTC455_38595 3288 68.49 Mlig455_010873

Neo: -

Age: Down-Up-Up

1.821 - - - 0.959 0.862 - Mlig455_010873 {REF} {Length: 1973} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=19.0]} {RNA1509_19874, RNA1509_50086} {RNA1310_24247.2, RNA1509_19874, RNA1509_50086} {RNA1509_19874, RNA1509_50086, RNA815_10484}
72. MligTC455_35894 23 0.48 Mlig455_029906

Neo: -

Age: -

RYK 1.819 0.838 - - - 0.981 - Mlig455_029906 {REF} {Length: 3571} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=210.1]; WIF domain [PF02019.20, score=110.2]; Protein kinase domain [PF00069.27, score=79.8]} {Human: ENSG00000163785, RYK, receptor-like tyrosine kinase, [Score=202, Expect=7e-57]} {Mouse: ENSMUSG00000032547, Ryk, receptor-like tyrosine kinase, [Score=202, Expect=9e-57]} {Dmel: FBgn0015380, drl, derailed, [RH, Score=241, Expect=7e-71]} {Celegans: WBGene00003007, lin-18, Inactive tyrosine-protein kinase RYK, [RH, Score=179, Expect=9e-49]} {Smed: dd_Smed_v6_12594_0_3, dd_Smed_v6_12594_0_3, [Score=201, Expect=2e-56]} {RNA1509_58811} {RNA1310_6671.2, RNA1509_58811} {RNA1509_58811, RNA815_41921}
73. MligTC455_50355 38 0.79 Mlig455_057631

Neo: -

Age: -

Region-enriched R2: 7.639/0.01837

1.819 0.847 - - - 0.972 - Mlig455_057631 {REF} {Length: 1003} {Pfam: WSC domain [PF01822.21, score=45.2]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=6e-06]} {RNA1310_44307} {RNA815_33128}
74. MligTC455_43315 118 2.46 Mlig455_022312, Mlig455_069884

Neo: -

Age: logFC(26M/2M)=0.730

KREMEN2 1.816 - - - 0.861 0.955 -

Mlig455_022312 {REF} {Length: 2816} {Pfam: WSC domain [PF01822.21, score=54.1]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.0, Expect=2e-07]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=50.1, Expect=5e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=63.9, Expect=1e-11]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=47.4, Expect=3e-06]} {RNA1509_40165} {RNA1310_40900} {RNA815_15848}

Mlig455_069884 {REF} {Length: 2143} {Pfam: WSC domain [PF01822.21, score=54.1]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.0, Expect=2e-07]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=50.1, Expect=5e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=63.9, Expect=1e-11]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=47.4, Expect=3e-06]} {RNA1509_40165} {RNA1310_40900} {RNA815_15848}
75. MligTC455_16874 38 0.8 Mlig455_028170

Neo: -

Age: -

KCNK18 1.812 0.845 - - - 0.967 - Mlig455_028170 {REF} {Length: 2452} {Pfam: Ion channel [PF07885.18, score=103.1]; Protein of unknown function (DUF3112) [PF11309.10, score=20.2]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [Score=96.7, Expect=1e-21]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=2e-23]} {Dmel: FBgn0033257, sand, sandman, [Score=129, Expect=2e-33]} {Celegans: WBGene00006680, twk-28, TWiK family of potassium channels, [Score=144, Expect=3e-38]} {Smed: dd_Smed_v6_17586_0_1, dd_Smed_v6_17586_0_1, [Score=270, Expect=2e-87]} {RNA1509_39975} {RNA1310_18301.1} {RNA815_12440}
76. MligTC455_34499 65 1.36 Mlig455_025160, Mlig455_063937

Neo: -

Age: -

1.81 0.845 - - - 0.965 -

Mlig455_025160 {REF} {Length: 942} {RNA1310_54940} {RNA815_33690.1}

Mlig455_063937 {REF} {Length: 995} {RNA1310_54940} {RNA815_33690.1}
77. MligTC455_10351 12 0.25 Mlig455_058454

Neo: -

Age: -

1.808 0.857 - - - 0.951 - Mlig455_058454 {REF} {Length: 1338} {RNA1310_148920}
78. MligTC455_39179 44 0.91 Mlig455_052012

Neo: -

Age: Down-Up-Up

TCTE3 1.805 0.849 - - - 0.956 - Mlig455_052012 {REF} {Length: 1042} {Pfam: Tctex-1 family [PF03645.15, score=42.5]} {Human: ENSG00000184786, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=65.9, Expect=8e-13]; ENSG00000275368, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=65.9, Expect=8e-13]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [Score=61.6, Expect=1e-11]} {Smed: dd_Smed_v6_9036_0_1, dd_Smed_v6_9036_0_1, [Score=92.8, Expect=1e-23]} {RNA1509_34873} {RNA1310_34743} {RNA815_18661}
79. MligTC455_21755 70 1.47 Mlig455_021213

Neo: -

Age: -

1.804 0.848 - - - 0.956 - Mlig455_021213 {REF} {Length: 4215} {Pfam: F5/8 type C domain [PF00754.27, score=55.5]} {RNA1509_2515} {RNA1310_33166} {RNA815_14716}
80. MligTC455_18035 45 0.94 Mlig455_000834

Neo: -

Age: -

1.801 - - - 0.959 0.842 - Mlig455_000834 {REF} {Length: 433} {NoTransDecoderORF} {RNA1509_37916} {RNA1310_32119.2} {RNA815_40336}
81. MligTC455_20105 19 0.39 Mlig455_031770

Neo: -

Age: -

GEM 1.8 0.832 - - - 0.968 - Mlig455_031770 {REF} {Length: 3348} {Pfam: Ras family [PF00071.24, score=56.4]} {Human: ENSG00000164949, GEM, GTP binding protein overexpressed in skeletal muscle, [Score=84.7, Expect=4e-18]; ENSG00000166592, RRAD, RRAD, Ras related glycolysis inhibitor and calcium channel regulator, [Score=82.0, Expect=5e-17]} {Mouse: ENSMUSG00000028214, Gem, GTP binding protein (gene overexpressed in skeletal muscle), [Score=84.3, Expect=5e-18]; ENSMUSG00000000359, Rem1, rad and gem related GTP binding protein 1, [Score=81.3, Expect=6e-17]} {Dmel: FBgn0085419, Rgk2, Rad, Gem/Kir family member 2, [Score=107, Expect=3e-25]} {Celegans: WBGene00021027, W04C9.5, [RH, Score=67.4, Expect=3e-12]} {Smed: dd_Smed_v6_11010_0_1, dd_Smed_v6_11010_0_1, [Score=147, Expect=9e-41]} {RNA1310_124922}
82. MligTC455_09697 52 1.08 Mlig455_009478, Mlig455_061921

Neo: -

Age: -

CD207 1.794 0.814 - - - 0.980 -

Mlig455_009478 {REF} {Length: 1068} {Pfam: Lectin C-type domain [PF00059.23, score=39.5]} {Human: ENSG00000116031, CD207, CD207 molecule, [Score=48.5, Expect=5e-06]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=1e-13]} {RNA1310_33496.1} {RNA815_23317}

Mlig455_061921 {REF} {Length: 776} {Pfam: Lectin C-type domain [PF00059.23, score=35.3]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=69.7, Expect=4e-14]} {RNA1310_33496.1} {RNA815_23317}
83. MligTC455_17412 44 0.91 Mlig455_069737

Neo: -

Age: -

Region-enriched R2: 5.062/0.00923

1.792 - - - 0.832 0.960 - Mlig455_069737 {REF} {Length: 1628} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=42.8]} {Smed: dd_Smed_v6_31564_0_1, dd_Smed_v6_31564_0_1, [Score=72.8, Expect=3e-14]} {RNA1310_45758} {RNA815_42912}
84. MligTC455_42510 125 2.6 Mlig455_025998, Mlig455_070424

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.702

1.79 0.828 - - - 0.962 -

Mlig455_025998 {REF} {Length: 1369} {RNA1310_73875.1}

Mlig455_070424 {REF} {Length: 1082} {RNA1310_73875.1}
85. MligTC455_40852 128 2.66 Mlig455_042301

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.671

Region-enriched R2: 6.158/0.00357

PKDREJ 1.785 0.795 - - - 0.990 - Mlig455_042301 {REF} {Length: 11184} {Pfam: Polycystin cation channel [PF08016.14, score=273.5]; PKD domain [PF00801.22, score=86.2]; PLAT/LH2 domain [PF01477.25, score=67.1]; REJ domain [PF02010.17, score=66.8]; PKD domain [PF18911.2, score=62.3]; Ion transport protein [PF00520.33, score=45.4]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=283, Expect=2e-75]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=273, Expect=2e-72]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=158, Expect=3e-38]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=254, Expect=4e-67]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=514, Expect=2e-146]} {RNA1509_8046} {RNA1310_93, RNA1509_8046} {RNA1509_8046, RNA815_1216}
86. MligTC455_44646 193 4.01 Mlig455_013515

Neo: -

Age: Down-Up-Down

SCNN1B 1.78 0.797 - - - 0.983 - Mlig455_013515 {REF} {Length: 2272} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=308.7]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [RH, Score=191, Expect=3e-52]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [RH, Score=188, Expect=3e-51]} {Dmel: FBgn0030795, ppk28, pickpocket 28, [Score=68.2, Expect=1e-11]} {Celegans: WBGene00012137, asic-2, Degenerin-like protein asic-2, [Score=143, Expect=2e-36]} {Smed: dd_Smed_v6_17021_0_1, dd_Smed_v6_17021_0_1, [Score=175, Expect=2e-47]} {RNA1509_52917} {RNA1310_12013.1, RNA1509_52917} {RNA1509_52917, RNA815_4777}
87. MligTC455_42659 2799 58.31 Mlig455_009046, Mlig455_058134

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.179

PACSIN2 1.779 - - 0.806 - 0.973 -

Mlig455_009046 {REF} {Length: 3055} {TRANSSPLICED} {Pfam: Variant SH3 domain [PF14604.8, score=54.6]; SH3 domain [PF00018.30, score=51.8]; Fes/CIP4, and EFC/F-BAR homology domain [PF00611.25, score=51.0]; Variant SH3 domain [PF07653.19, score=34.2]} {Human: ENSG00000100266, PACSIN2, protein kinase C and casein kinase substrate in neurons 2, [Score=325, Expect=5e-105]} {Mouse: ENSMUSG00000016664, Pacsin2, protein kinase C and casein kinase substrate in neurons 2, [RH, Score=335, Expect=2e-109]} {Dmel: FBgn0053094, Synd, Syndapin, [Score=285, Expect=4e-90]} {Celegans: WBGene00018467, sdpn-1, SynDaPiN (Synaptic dynamin binding protein) homolog, [Score=219, Expect=6e-65]} {Smed: dd_Smed_v6_7987_0_1, dd_Smed_v6_7987_0_1, [Score=351, Expect=1e-115]} {RNA1509_22117, RNA1509_37584} {RNA1310_9530, RNA1509_22117} {RNA1509_22117, RNA815_8193}

Mlig455_058134 {REF} {Length: 3083} {TRANSSPLICED} {Pfam: Variant SH3 domain [PF14604.8, score=54.5]; SH3 domain [PF00018.30, score=51.7]; Fes/CIP4, and EFC/F-BAR homology domain [PF00611.25, score=50.9]; Variant SH3 domain [PF07653.19, score=34.1]} {Human: ENSG00000100266, PACSIN2, protein kinase C and casein kinase substrate in neurons 2, [Score=322, Expect=1e-103]} {Mouse: ENSMUSG00000016664, Pacsin2, protein kinase C and casein kinase substrate in neurons 2, [Score=329, Expect=9e-107]} {Dmel: FBgn0053094, Synd, Syndapin, [Score=286, Expect=5e-90]} {Celegans: WBGene00018467, sdpn-1, SynDaPiN (Synaptic dynamin binding protein) homolog, [Score=187, Expect=7e-53]} {Smed: dd_Smed_v6_7987_0_1, dd_Smed_v6_7987_0_1, [Score=337, Expect=4e-110]} {RNA1509_37584} {RNA1310_9122.1} {RNA815_8193}
88. MligTC455_34896 906 18.87 Mlig455_041044, Mlig455_070071

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.259

Region-enriched R2: 2.266/0.02183

1.777 - 0.806 - - 0.971 -

Mlig455_041044 {REF} {Length: 7002} {TRANSSPLICED} {Pfam: Fibronectin type III domain [PF00041.23, score=34.4]; Scramblase [PF03803.17, score=18.5]} {Smed: dd_Smed_v6_66647_0_1, dd_Smed_v6_66647_0_1, [Score=113, Expect=8e-28]} {RNA1509_18182} {RNA1310_652.1} {RNA815_333}

Mlig455_070071 {REF} {Length: 6980} {TRANSSPLICED} {Pfam: Fibronectin type III domain [PF00041.23, score=34.6]; Scramblase [PF03803.17, score=18.4]} {Smed: dd_Smed_v6_66647_0_1, dd_Smed_v6_66647_0_1, [Score=113, Expect=8e-28]} {RNA1509_18182} {RNA1310_652.1} {RNA815_333}
89. MligTC455_37792 210 4.38 Mlig455_024774

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.926

Region-enriched R2: 6.055/0.00271

PKD1L2 1.775 - - - - 0.984 0.791 Mlig455_024774 {REF} {Length: 6374} {Pfam: Polycystin cation channel [PF08016.14, score=224.6]; PLAT/LH2 domain [PF01477.25, score=66.8]; Ion transport protein [PF00520.33, score=30.8]} {Human: ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [Score=179, Expect=9e-45]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=187, Expect=3e-47]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=109, Expect=1e-23]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=187, Expect=2e-47]} {Smed: dd_Smed_v6_13975_0_1, dd_Smed_v6_13975_0_1, [Score=902, Expect=0.0]} {RNA1509_46134} {RNA1310_488} {RNA815_1711}
90. MligTC455_16014 135 2.81 Mlig455_057808

Neo: -

Age: -

SLC6A3 1.773 - - - - 0.959 0.814 Mlig455_057808 {REF} {Length: 3595} {tRNA: Undet(NNN),pseudo, score=28.6} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=586.5]} {Human: ENSG00000142319, SLC6A3, solute carrier family 6 member 3, [Score=521, Expect=1e-177]; ENSG00000276996, SLC6A3, solute carrier family 6 member 3, [Score=521, Expect=1e-177]; ENSG00000103546, SLC6A2, solute carrier family 6 member 2, [Score=505, Expect=1e-171]} {Mouse: ENSMUSG00000021609, Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, [Score=523, Expect=1e-178]; ENSMUSG00000055368, Slc6a2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, [Score=511, Expect=3e-174]} {Dmel: FBgn0010414, SerT, Serotonin transporter, [Score=468, Expect=2e-157]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=433, Expect=4e-144]} {Smed: dd_Smed_v6_22486_0_1, dd_Smed_v6_22486_0_1, [RH, Score=571, Expect=0.0]} {RNA1509_41282} {RNA1310_11169, RNA1509_41282} {RNA1509_41282, RNA815_3966}
91. MligTC455_17688 323 6.72 Mlig455_015433, Mlig455_032147

Neo: -

Age: Up-Down-Down

PLRG1 1.772 - 0.812 - - 0.960 -

Mlig455_015433 {REF} {Length: 2963} {Pfam: F-box-like [PF12937.9, score=21.7]} {Human: ENSG00000171566, PLRG1, pleiotropic regulator 1, [Score=58.2, Expect=2e-08]} {Mouse: ENSMUSG00000027998, Plrg1, pleiotropic regulator 1, [Score=56.2, Expect=7e-08]} {Dmel: FBgn0030365, Tango4, Transport and Golgi organization 4, [Score=53.5, Expect=3e-07]} {Smed: dd_Smed_v6_13495_0_1, dd_Smed_v6_13495_0_1, [RH, Score=112, Expect=2e-26]} {RNA1310_25949} {RNA815_29895}

Mlig455_032147 {REF} {Length: 3089} {TRANSSPLICED} {Pfam: F-box-like [PF12937.9, score=21.7]} {Human: ENSG00000171566, PLRG1, pleiotropic regulator 1, [Score=58.2, Expect=2e-08]} {Mouse: ENSMUSG00000027998, Plrg1, pleiotropic regulator 1, [Score=56.2, Expect=6e-08]} {Dmel: FBgn0030365, Tango4, Transport and Golgi organization 4, [Score=53.5, Expect=3e-07]} {Smed: dd_Smed_v6_13495_0_1, dd_Smed_v6_13495_0_1, [RH, Score=111, Expect=3e-26]} {RNA1310_25949} {RNA815_29895}
92. MligTC455_54301 10407 216.81 Mlig455_061141

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.453

1.769 - - - 0.806 - 0.963 Mlig455_061141 {REF} {Length: 896} {RNA1509_4003} {RNA1310_87474} {RNA815_2608.1}
93. MligTC455_03587 28 0.59 Mlig455_032271, Mlig455_068492

Neo: -

Age: -

Region-enriched R4: 6.165/0.03605

1.766 0.803 - - - 0.963 -

Mlig455_032271 {REF} {Length: 453} {NoTransDecoderORF}

Mlig455_068492 {REF} {Length: 473} {NoTransDecoderORF}
94. MligTC455_49365 148 3.08 Mlig455_017917

Neo: -

Age: logFC(26M/2M)=-0.372

1.765 - - - 0.810 0.955 - Mlig455_017917 {REF} {Length: 1359} {RNA1310_37310.3} {RNA815_21947}
95. MligTC455_22505 333 6.93 Mlig455_024720

Neo: -

Age: Up-Down-Down

FAT4 1.758 - - - 0.807 0.951 - Mlig455_024720 {REF} {Length: 8220} {Pfam: Cadherin domain [PF00028.19, score=772.9]; Cadherin-like [PF16184.7, score=85.1]; Cadherin-like [PF08266.14, score=59.8]; RET Cadherin like domain 1 [PF17756.3, score=41.7]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=610, Expect=9e-177]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=608, Expect=5e-176]} {Dmel: FBgn0001075, ft, fat, [Score=536, Expect=2e-153]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=323, Expect=2e-88]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=288, Expect=1e-77]} {RNA1509_477} {RNA1310_252.2} {RNA815_84}
96. MligTC455_22568 756 15.74 Mlig455_006710

Neo: -

Age: Up-Down-Down

TRPM3 1.756 0.804 - - - 0.952 - Mlig455_006710 {REF} {Length: 6137} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=107.2]; Ankyrin repeats (3 copies) [PF12796.9, score=92.9]; Ankyrin repeat [PF00023.32, score=63.3]; Ankyrin repeats (many copies) [PF13857.8, score=59.6]; Ankyrin repeat [PF13606.8, score=58.2]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=111, Expect=7e-24]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=111, Expect=5e-24]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=105, Expect=3e-22]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=64.3, Expect=6e-10]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=120, Expect=3e-27]} {RNA1509_12598} {RNA1310_943.1} {RNA815_2516.1}
97. MligTC455_12812 58 1.21 Mlig455_027688, Mlig455_047749

Neo: -

Age: Up-Down-Down

1.755 - - - 0.776 0.979 -

Mlig455_027688 {REF} {Length: 2289} {Pfam: Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=18.6]} {RNA1509_59038} {RNA1310_64936.1, RNA1509_59038}

Mlig455_047749 {REF} {Length: 2332} {RNA1509_59038} {RNA1310_67234}
98. MligTC455_40851 132 2.76 Mlig455_042077

Neo: -

Age: logFC(26M/2M)=0.724

Region-enriched R2: 3.969/0.02676

PKD1L2 1.748 0.756 - - - 0.992 - Mlig455_042077 {REF} {Length: 4836} {Pfam: PLAT/LH2 domain [PF01477.25, score=68.6]; Polycystin cation channel [PF08016.14, score=53.9]} {Human: ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [Score=220, Expect=3e-58]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=212, Expect=7e-56]} {Dmel: FBgn0050048, CG30048, [Score=55.8, Expect=2e-07]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=122, Expect=1e-27]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=328, Expect=2e-94]} {RNA1509_8046} {RNA1310_93} {RNA815_1216}
99. MligTC455_45977 2671 55.65 Mlig455_023593, Mlig455_068112

Neo: -

Age: logFC(26M/2M)=-0.892

Region-enriched R2: 2.870/0.00031

MUC4 1.747 - - - - 0.970 0.777

Mlig455_023593 {REF} {Length: 6716} {TRANSSPLICED} {Pfam: Calcium-binding EGF domain [PF07645.17, score=81.4]; EGF-like domain [PF00008.29, score=74.6]; EGF domain [PF12947.9, score=64.6]; Complement Clr-like EGF-like [PF12662.9, score=58.7]; von Willebrand factor type D domain [PF00094.27, score=54.6]; Coagulation Factor Xa inhibitory site [PF14670.8, score=40.9]; Human growth factor-like EGF [PF12661.9, score=38.7]; Nidogen-like [PF06119.16, score=25.5]} {Human: ENSG00000278303, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000145113, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000277585, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000273822, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000273984, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000276613, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000278468, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=6e-31]} {Mouse: ENSMUSG00000079620, Muc4, mucin 4, [RH, Score=112, Expect=6e-24]} {Dmel: FBgn0004647, N, Notch, [Score=103, Expect=2e-21]} {Celegans: WBGene00000792, crb-1, Drosophila CRumBs homolog, [Score=94.0, Expect=1e-18]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=92.0, Expect=3e-18]} {RNA1509_5446} {RNA1310_1366} {RNA815_327.2}

Mlig455_068112 {REF} {Length: 6638} {TRANSSPLICED} {Pfam: Calcium-binding EGF domain [PF07645.17, score=82.1]; EGF-like domain [PF00008.29, score=75.3]; EGF domain [PF12947.9, score=65.2]; Complement Clr-like EGF-like [PF12662.9, score=59.4]; von Willebrand factor type D domain [PF00094.27, score=54.7]; Coagulation Factor Xa inhibitory site [PF14670.8, score=41.6]; Human growth factor-like EGF [PF12661.9, score=39.4]; Nidogen-like [PF06119.16, score=25.6]} {Human: ENSG00000273822, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000277585, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000276613, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000273984, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000278303, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000145113, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=7e-31]; ENSG00000278468, MUC4, mucin 4, cell surface associated, [RH, Score=133, Expect=3e-30]} {Mouse: ENSMUSG00000079620, Muc4, mucin 4, [RH, Score=110, Expect=2e-23]} {Dmel: FBgn0004647, N, Notch, [Score=103, Expect=2e-21]} {Celegans: WBGene00000792, crb-1, Drosophila CRumBs homolog, [Score=93.6, Expect=1e-18]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=92.4, Expect=3e-18]} {RNA1509_20713, RNA1509_53794, RNA1509_5446} {RNA1310_1366, RNA1509_20713, RNA1509_53794} {RNA1509_20713, RNA1509_53794, RNA815_327.2}
100. MligTC455_26255 126 2.63 Mlig455_053706

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.424/0.00107
Region-enriched R4: 3.360/0.04239

FZD5 1.742 0.787 - - - 0.955 - Mlig455_053706 {REF} {Length: 3671} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=393.1]; Fz domain [PF01392.24, score=105.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [RH, Score=607, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=600, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [RH, Score=562, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [RH, Score=412, Expect=5e-137]} {Smed: dd_Smed_v6_11823_0_1, dd_Smed_v6_11823_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_49831} {RNA1310_28187, RNA1509_49831} {RNA1509_49831, RNA815_16996}

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