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Results for MligTC455_46155

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_46155 116 2.42 Mlig455_027239

Neo: -

Age: -

Region-enriched R2: 4.163/0.03818

 GRK3 Mlig455_027239 {REF} {Length: 2919} {Pfam: Protein kinase domain [PF00069.27, score=226.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=100.5]; Regulator of G protein signaling domain [PF00615.21, score=48.3]} {Human: ENSG00000100077, GRK3, G protein-coupled receptor kinase 3, [Score=845, Expect=0.0]; ENSG00000173020, GRK2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Mouse: ENSMUSG00000042249, Grk3, G protein-coupled receptor kinase 3, [Score=838, Expect=0.0]; ENSMUSG00000024858, Grk2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Dmel: FBgn0260798, Gprk1, G protein-coupled receptor kinase 1, [Score=842, Expect=0.0]} {Celegans: WBGene00001709, grk-2, G protein-coupled receptor kinase 2, [Score=819, Expect=0.0]} {Smed: dd_Smed_v6_6480_0_1, dd_Smed_v6_6480_0_1, [Score=949, Expect=0.0]} {RNA1509_7002} {RNA1310_16658} {RNA815_28070}

Cumulative graph for MligTC455_46155

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.831 2.207 1.00000 1.00000
RegionR2 4.163 2.207 0.00226 0.03818
RegionR3 -0.103 2.207 0.71975 1.00000
RegionR4 1.121 2.207 0.33911 0.65872
RegionR5 -0.339 2.207 0.76144 1.00000
RegionR6 1.864 2.207 0.13403 0.65849
RegionR7 -2.748 2.207 0.99974 1.00000
RegionR8 -2.126 2.207 0.99970 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.533 2.207 0.99991 1.00000
RegenerationR2 0.293 2.207 0.62604 0.92538
RegenerationR3 1.844 2.207 0.09362 0.49208
RegenerationR4 0.537 2.207 0.61608 0.91933
RegenerationR5 0.784 2.207 0.41090 0.80620
RegenerationR6 -0.404 2.207 0.62275 0.88249
RegenerationBL 1.486 2.207 0.40443 0.77343
RegenerationTP 3.234 2.207 0.21531 0.65808


Genes with expression patterns similar to MligTC455_46155

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_46155 116 2.42 Mlig455_027239

Neo: -

Age: -

Region-enriched R2: 4.163/0.03818

 GRK3 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_027239 {REF} {Length: 2919} {Pfam: Protein kinase domain [PF00069.27, score=226.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=100.5]; Regulator of G protein signaling domain [PF00615.21, score=48.3]} {Human: ENSG00000100077, GRK3, G protein-coupled receptor kinase 3, [Score=845, Expect=0.0]; ENSG00000173020, GRK2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Mouse: ENSMUSG00000042249, Grk3, G protein-coupled receptor kinase 3, [Score=838, Expect=0.0]; ENSMUSG00000024858, Grk2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Dmel: FBgn0260798, Gprk1, G protein-coupled receptor kinase 1, [Score=842, Expect=0.0]} {Celegans: WBGene00001709, grk-2, G protein-coupled receptor kinase 2, [Score=819, Expect=0.0]} {Smed: dd_Smed_v6_6480_0_1, dd_Smed_v6_6480_0_1, [Score=949, Expect=0.0]} {RNA1509_7002} {RNA1310_16658} {RNA815_28070}
2. MligTC455_19249 90 1.86 Mlig455_054092

Neo: -

Age: Down-Up-Up

Region-enriched R2: 7.298/0.00139

 5.343 0.971 0.850 0.835 0.892 0.932 0.863 Mlig455_054092 {REF} {Length: 667} {TRANSSPLICED} {RNA1509_57448} {RNA1310_51394, RNA1509_57448} {RNA1509_57448, RNA815_26076}
3. MligTC455_17363 62 1.28 Mlig455_003936

Neo: -

Age: -

 5.299 0.945 0.918 0.819 0.848 0.950 0.819 Mlig455_003936 {REF} {Length: 1252} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=45.9]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=26.4]} {RNA1310_47889} {RNA815_24646}
4. MligTC455_12102 59 1.23 Mlig455_041538, Mlig455_053099

Neo: -

Age: -

Region-enriched R2: 6.626/0.00371

 DEGS2 5.252 0.959 0.909 0.848 0.976 0.740 0.820

Mlig455_041538 {REF} {Length: 1966} {Pfam: Fatty acid desaturase [PF00487.26, score=87.9]; Sphingolipid Delta4-desaturase (DES) [PF08557.12, score=57.6]} {Human: ENSG00000168350, DEGS2, delta 4-desaturase, sphingolipid 2, [Score=319, Expect=2e-107]; ENSG00000143753, DEGS1, delta 4-desaturase, sphingolipid 1, [Score=315, Expect=5e-106]} {Mouse: ENSMUSG00000038633, Degs1, delta(4)-desaturase, sphingolipid 1, [Score=308, Expect=2e-103]; ENSMUSG00000021263, Degs2, delta(4)-desaturase, sphingolipid 2, [Score=307, Expect=6e-103]} {Dmel: FBgn0001941, ifc, infertile crescent, [Score=345, Expect=5e-118]} {Celegans: WBGene00017996, F33D4.4, Putative sphingolipid delta(4)-desaturase, [Score=318, Expect=4e-107]} {Smed: dd_Smed_v6_7414_0_1, dd_Smed_v6_7414_0_1, [RH, Score=409, Expect=7e-143]} {RNA1310_20672.2} {RNA815_19986}

Mlig455_053099 {REF} {Length: 2009} {Pfam: Fatty acid desaturase [PF00487.26, score=87.9]; Sphingolipid Delta4-desaturase (DES) [PF08557.12, score=57.5]} {Human: ENSG00000168350, DEGS2, delta 4-desaturase, sphingolipid 2, [Score=319, Expect=2e-107]; ENSG00000143753, DEGS1, delta 4-desaturase, sphingolipid 1, [Score=315, Expect=4e-106]} {Mouse: ENSMUSG00000038633, Degs1, delta(4)-desaturase, sphingolipid 1, [Score=309, Expect=7e-104]; ENSMUSG00000021263, Degs2, delta(4)-desaturase, sphingolipid 2, [Score=307, Expect=5e-103]} {Dmel: FBgn0001941, ifc, infertile crescent, [Score=345, Expect=4e-118]} {Celegans: WBGene00017996, F33D4.4, Putative sphingolipid delta(4)-desaturase, [Score=318, Expect=3e-107]} {Smed: dd_Smed_v6_7414_0_1, dd_Smed_v6_7414_0_1, [RH, Score=409, Expect=4e-143]} {RNA1310_20672.1} {RNA815_19986}
5. MligTC455_11558 137 2.85 Mlig455_058259

Neo: -

Age: logFC(26M/2M)=-0.792

 5.194 0.936 0.770 0.798 0.878 0.963 0.849 Mlig455_058259 {REF} {Length: 896} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=19.9]} {RNA1509_58923} {RNA1310_41706, RNA1509_58923} {RNA1509_58923, RNA815_20876}
6. MligTC455_44966 574 11.95 Mlig455_036578, Mlig455_057773

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.756

Region-specific R2: 7.016

Region-enriched R2: 7.690/0.00000

 5.174 0.948 0.812 0.770 0.860 0.960 0.824

Mlig455_036578 {REF} {Length: 1101} {RNA1509_34765} {RNA1310_57079} {RNA815_29388}

Mlig455_057773 {REF} {Length: 629} {RNA1509_34765} {RNA1310_57079, RNA1509_34765} {RNA1509_34765, RNA815_29388}
7. MligTC455_13902 400 8.32 Mlig455_011022, Mlig455_011835, Mlig455_013117

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.562

Region-specific R2: 6.064

Region-enriched R2: 5.080/0.00072

 5.136 0.773 0.922 0.765 0.855 0.970 0.851

Mlig455_011022 {REF} {Length: 631} {RNA1509_28527} {RNA1310_38436.1} {RNA815_28856}

Mlig455_011835 {REF} {Length: 2387} {RNA1509_28527} {RNA1310_38436.1} {RNA815_28856}

Mlig455_013117 {REF} {Length: 1663} {NoTransDecoderORF} {RNA1310_40518} {RNA815_20411.2}
8. MligTC455_46430 62 1.29 Mlig455_057117, Mlig455_069301

Neo: -

Age: -

 GUCY2F 5.103 0.967 0.737 0.768 0.836 0.981 0.814

Mlig455_057117 {REF} {Length: 2651} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=196.0]; Nitrate and nitrite sensing [PF08376.12, score=82.5]; Heme NO binding associated [PF07701.16, score=28.2]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=247, Expect=9e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=242, Expect=3e-68]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=238, Expect=5e-67]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=246, Expect=7e-70]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=242, Expect=2e-68]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=241, Expect=7e-68]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=239, Expect=3e-67]} {Dmel: FBgn0053958, CG33958, [Score=266, Expect=4e-79]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=235, Expect=3e-66]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=238, Expect=4e-67]} {RNA1509_38781} {RNA1310_35456} {RNA815_22108}

Mlig455_069301 {REF} {Length: 2370} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=178.1]; Nitrate and nitrite sensing [PF08376.12, score=82.3]; Heme NO binding associated [PF07701.16, score=28.0]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=232, Expect=2e-64]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=232, Expect=1e-64]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=225, Expect=5e-62]} {Dmel: FBgn0053958, CG33958, [Score=250, Expect=5e-73]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=223, Expect=1e-61]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=221, Expect=4e-61]} {RNA1509_38781} {RNA1310_35456} {RNA815_24181}
9. MligTC455_21182 238 4.96 Mlig455_000068, Mlig455_063733

Neo: -

Age: Down-Up-Up

Region-enriched R4: 5.301/0.04587

 5.066 0.948 0.791 0.829 0.965 0.803 0.730

Mlig455_000068 {REF} {Length: 468} {Pfam: Pancreatic hormone peptide [PF00159.20, score=23.7]} {RNA1310_81800.1} {RNA815_55075}

Mlig455_063733 {REF} {Length: 531} {Pfam: Pancreatic hormone peptide [PF00159.20, score=20.7]} {RNA1310_81800.1} {RNA815_55075}
10. MligTC455_52656 121 2.51 Mlig455_062381, Mlig455_062408

Neo: -

Age: Down-Up-Down

 5.004 0.957 0.742 0.702 0.942 0.838 0.823

Mlig455_062381 {REF} {Length: 2245} {RNA1310_26272} {RNA815_22826}

Mlig455_062408 {REF} {Length: 2277} {RNA1310_26272} {RNA815_37592}
11. MligTC455_44712 665 13.86 Mlig455_017186

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.471

Region-specific R2: 4.141

Region-enriched R2: 3.536/0.00000

 4.993 0.731 0.724 0.786 0.953 0.934 0.865 Mlig455_017186 {REF} {Length: 1018} {RNA1509_34252} {RNA1310_54269.1} {RNA815_55074}
12. MligTC455_48756 622 12.96 Mlig455_054772, Mlig455_054799, Mlig455_054893

Neo: -

Age: -

Region-specific R2: 7.873

Region-enriched R2: 9.003/0.00000

 4.906 0.728 0.762 0.818 0.828 0.952 0.818

Mlig455_054772 {REF} {Length: 716} {RNA1509_41507} {RNA1310_49516} {RNA815_28703}

Mlig455_054799 {REF} {Length: 625} {RNA1509_41507} {RNA1310_49516} {RNA815_28703}

Mlig455_054893 {REF} {Length: 947} {RNA1509_41507} {RNA1310_49516, RNA1509_41507} {RNA1509_41507, RNA815_28703}
13. MligTC455_19328 99 2.06 Mlig455_062531

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.972/0.00232

 4.825 0.953 0.724 0.802 0.702 0.903 0.741 Mlig455_062531 {REF} {Length: 1929} {NoTransDecoderORF} {RNA1509_36058} {RNA1310_3092} {RNA815_16673}
14. MligTC455_42484 246 5.12 Mlig455_046416

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.313

Region-enriched R2: 2.983/0.00930

 4.623 0.958 0.847 - 0.924 0.973 0.921 Mlig455_046416 {REF} {Length: 1006} {RNA1310_40237.1} {RNA815_18246}
15. MligTC455_44713 661 13.77 Mlig455_048154

Neo: -

Age: logFC(26M/2M)=0.569

Region-specific R2: 3.883

Region-enriched R2: 3.422/0.00000

 4.566 0.938 - 0.836 0.954 0.942 0.896 Mlig455_048154 {REF} {Length: 1173} {RNA1509_34252} {RNA1310_54269.1} {RNA815_55074}
16. MligTC455_15184 33 0.69 Mlig455_065087

Neo: -

Age: -

 4.531 0.948 - 0.836 0.961 0.970 0.816 Mlig455_065087 {REF} {Length: 2555} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=183.3]} {Mouse: ENSMUSG00000030340, Scnn1a, sodium channel, nonvoltage-gated 1 alpha, [Score=48.5, Expect=1e-05]} {Celegans: WBGene00009073, delm-1, DEgenerin Linked to Mechanosensation, [Score=68.2, Expect=1e-11]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [RH, Score=125, Expect=3e-30]} {RNA1310_11413} {RNA815_11497}
17. MligTC455_14483 140 2.92 Mlig455_028240

Neo: -

Age: -

Region-enriched R2: 6.203/0.04837

 4.468 0.945 0.868 - 0.864 0.982 0.809 Mlig455_028240 {REF} {Length: 728} {RNA1310_111517} {RNA815_9716}
18. MligTC455_16908 161 3.35 Mlig455_046916

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.397

Region-enriched R2: 2.938/0.02849

 SLC17A6 4.456 0.947 0.878 - 0.954 0.835 0.842 Mlig455_046916 {REF} {Length: 3198} {Pfam: Major Facilitator Superfamily [PF07690.18, score=172.0]; Uncharacterised MFS-type transporter YbfB [PF06779.16, score=19.6]} {Human: ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=548, Expect=0.0]; ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=542, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=536, Expect=0.0]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=551, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=547, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=543, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=482, Expect=6e-163]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=479, Expect=7e-163]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=591, Expect=0.0]} {RNA1509_38152} {RNA1310_23072, RNA1509_38152} {RNA1509_38152, RNA815_14894}
19. MligTC455_43602 1418 29.54 Mlig455_053986

Neo: -

Age: -

Region-specific R2: 4.626

Region-enriched R2: 3.844/0.00000

Regeneration-downregulated R2: -2.432

Regeneration-depleted R2: -2.432

 4.419 0.835 - 0.818 0.910 0.951 0.905 Mlig455_053986 {REF} {Length: 2161} {RNA1509_15576} {RNA1310_12096.1} {RNA815_32931}
20. MligTC455_19329 90 1.88 Mlig455_068578

Neo: -

Age: -

Region-enriched R2: 3.988/0.02701

 CHAT 4.417 0.977 0.815 0.822 0.853 0.950 - Mlig455_068578 {REF} {Length: 3661} {TRANSSPLICED} {Pfam: Choline/Carnitine o-acyltransferase [PF00755.22, score=556.7]} {Human: ENSG00000070748, CHAT, choline O-acetyltransferase, [RH, Score=519, Expect=2e-177]} {Mouse: ENSMUSG00000021919, Chat, choline acetyltransferase, [RH, Score=520, Expect=7e-178]} {Dmel: FBgn0000303, ChAT, Choline acetyltransferase, [RH, Score=488, Expect=1e-164]} {Celegans: WBGene00000481, cha-1, Choline O-acetyltransferase, [RH, Score=363, Expect=2e-117]} {Smed: dd_Smed_v6_6208_0_1, dd_Smed_v6_6208_0_1, [RH, Score=601, Expect=0.0]} {RNA1509_36058} {RNA1310_3092, RNA1509_36058} {RNA1509_36058, RNA815_2435.1}
21. MligTC455_47420 218 4.54 Mlig455_017159, Mlig455_048110

Neo: -

Age: -

Region-specific R2: 6.469

Region-enriched R2: 5.851/0.00135

 4.417 0.929 - 0.792 0.898 0.969 0.829

Mlig455_017159 {REF} {Length: 1062} {RNA1509_35349} {RNA1310_81586}

Mlig455_048110 {REF} {Length: 527} {RNA1310_81586}
22. MligTC455_53546 130 2.72 Mlig455_013326, Mlig455_013334

Neo: -

Age: -

Region-enriched R2: 6.753/0.01892

 MMP9 4.416 0.743 - 0.905 0.949 0.965 0.854

Mlig455_013326 {REF} {Length: 1449} {Pfam: Fibronectin type II domain [PF00040.21, score=92.5]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=87.8, Expect=3e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=82.4, Expect=1e-16]; ENSMUSG00000031740, Mmp2, matrix metallopeptidase 2, [RH, Score=78.6, Expect=2e-15]} {Smed: dd_Smed_v6_14558_0_1, dd_Smed_v6_14558_0_1, [RH, Score=138, Expect=3e-38]} {RNA1310_38631} {RNA815_51136}

Mlig455_013334 {REF} {Length: 1398} {Pfam: Fibronectin type II domain [PF00040.21, score=92.1]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=89.4, Expect=1e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=84.0, Expect=4e-17]} {Smed: dd_Smed_v6_12601_0_1, dd_Smed_v6_12601_0_1, [RH, Score=140, Expect=2e-38]} {RNA1310_38631} {RNA815_51136}
23. MligTC455_20953 115 2.4 Mlig455_002904

Neo: -

Age: -

Region-enriched R2: 5.041/0.00953

 4.401 - 0.781 0.893 0.937 0.990 0.800 Mlig455_002904 {REF} {Length: 1514} {RNA1310_19276} {RNA815_20827}
24. MligTC455_50694 602 12.54 Mlig455_058794, Mlig455_070066

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.478

Region-enriched R2: 3.805/0.01454

 4.389 0.897 - 0.804 0.863 0.981 0.844

Mlig455_058794 {REF} {Length: 776} {RNA1310_76208} {RNA815_49041}

Mlig455_070066 {REF} {Length: 781} {RNA1310_76208} {RNA815_49041}
25. MligTC455_50172 243 5.05 Mlig455_067182

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.036

Region-enriched R2: 6.524/0.00000

 4.37 0.775 - 0.864 0.939 0.951 0.841 Mlig455_067182 {REF} {Length: 638} {Pfam: Pancreatic hormone peptide [PF00159.20, score=47.5]} {RNA1509_60030} {RNA1310_56761, RNA1509_60030} {RNA1509_60030, RNA815_31877.1}
26. MligTC455_54282 74 1.54 Mlig455_020191

Neo: -

Age: -

 4.367 - 0.909 0.832 0.816 0.965 0.845 Mlig455_020191 {REF} {Length: 937} {RNA1509_48973} {RNA1310_40738.2} {RNA815_31898}
27. MligTC455_44328 858 17.88 Mlig455_026172

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.714

Region-enriched R2: 4.385/0.00000

 4.351 0.777 - 0.804 0.964 0.978 0.828 Mlig455_026172 {REF} {Length: 661} {RNA1509_32102, RNA1509_34635} {RNA1310_60068, RNA1509_32102, RNA1509_34635} {RNA1509_32102, RNA1509_34635, RNA815_37486}
28. MligTC455_45350 92 1.93 Mlig455_024760, Mlig455_058317, Mlig455_068656

Neo: -

Age: Up-Down-Down

 SLC17A6, SLC17A8 4.351 0.905 - 0.823 0.862 0.956 0.805

Mlig455_024760 {REF} {Length: 2935} {Pfam: Major Facilitator Superfamily [PF07690.18, score=158.2]} {Human: ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=522, Expect=5e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=530, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=527, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=487, Expect=1e-165]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=474, Expect=3e-161]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=583, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}

Mlig455_058317 {REF} {Length: 2971} {Pfam: Major Facilitator Superfamily [PF07690.18, score=157.7]} {Human: ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=534, Expect=0.0]; ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=521, Expect=8e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=531, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=526, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=485, Expect=1e-164]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [Score=474, Expect=7e-162]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [Score=585, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}

Mlig455_068656 {REF} {Length: 3034} {Pfam: Major Facilitator Superfamily [PF07690.18, score=158.2]} {Human: ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=522, Expect=5e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=530, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=527, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=487, Expect=1e-165]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=474, Expect=3e-161]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=583, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}
29. MligTC455_32164 149 3.11 Mlig455_028109

Neo: -

Age: -

 4.346 0.906 0.727 0.852 - 0.990 0.871 Mlig455_028109 {REF} {Length: 205} {NoTransDecoderORF} {RNA1310_31190} {RNA815_49804}
30. MligTC455_32165 302 6.3 Mlig455_028110, Mlig455_045231, Mlig455_069146

Neo: -

Age: -

 4.341 0.905 0.727 0.853 - 0.990 0.866

Mlig455_028110 {REF} {Length: 668} {Pfam: PMP-22/EMP/MP20/Claudin family [PF00822.22, score=31.4]; PMP-22/EMP/MP20/Claudin tight junction [PF13903.8, score=19.9]} {Smed: dd_Smed_v6_7982_0_1, dd_Smed_v6_7982_0_1, [Score=69.7, Expect=4e-14]} {RNA1310_31139.2} {RNA815_42018}

Mlig455_045231 {REF} {Length: 2983} {Pfam: PMP-22/EMP/MP20/Claudin family [PF00822.22, score=46.7]} {Smed: dd_Smed_v6_7982_0_1, dd_Smed_v6_7982_0_1, [RH, Score=115, Expect=4e-29]} {RNA1509_55345} {RNA1310_31139.1} {RNA815_42018}

Mlig455_069146 {REF} {Length: 1639} {Pfam: PMP-22/EMP/MP20/Claudin family [PF00822.22, score=40.1]} {Smed: dd_Smed_v6_16515_0_1, dd_Smed_v6_16515_0_1, [RH, Score=99.0, Expect=7e-25]} {RNA1310_31190} {RNA815_42018}
31. MligTC455_46543 178 3.7 Mlig455_000344, Mlig455_067946

Neo: -

Age: -

Region-specific R2: 6.098

Region-enriched R2: 6.851/0.00000

 4.333 0.827 - 0.834 0.931 0.974 0.767

Mlig455_000344 {REF} {Length: 1920} {RNA1310_82457} {RNA815_33120}

Mlig455_067946 {REF} {Length: 1217} {RNA1310_99435}
32. MligTC455_45811 216 4.5 Mlig455_015628

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.807/0.00004

 4.318 - 0.922 0.732 0.859 0.980 0.825 Mlig455_015628 {REF} {Length: 1061} {RNA1310_43338} {RNA815_24238}
33. MligTC455_34524 155 3.22 Mlig455_021291

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.905

Region-enriched R2: 4.200/0.01842

 4.31 0.971 - 0.832 0.874 0.832 0.801 Mlig455_021291 {REF} {Length: 1478} {NoTransDecoderORF} {RNA1509_56543} {RNA1310_26920, RNA1509_56543} {RNA1509_56543, RNA815_11718}
34. MligTC455_21502 36 0.75 Mlig455_018529

Neo: -

Age: -

Region-enriched R2: 5.380/0.01311

 4.303 0.949 - 0.708 0.811 0.980 0.855 Mlig455_018529 {REF} {Length: 1004} {Pfam: Fas apoptotic inhibitory molecule (FAIM1) [PF06905.15, score=43.7]} {Mouse: ENSMUSG00000032463, Faim, Fas apoptotic inhibitory molecule, [Score=54.7, Expect=2e-09]} {Smed: dd_Smed_v6_4798_0_1, dd_Smed_v6_4798_0_1, [RH, Score=75.1, Expect=7e-18]} {RNA1310_42034} {RNA815_19884}
35. MligTC455_25073 1271 26.47 Mlig455_015905

Neo: -

Age: logFC(26M/2M)=-0.947

Region-specific R2: 3.291

Region-enriched R2: 2.110/0.00052

 PI16 4.3 0.832 0.834 - 0.956 0.882 0.796 Mlig455_015905 {REF} {Length: 2189} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=71.8]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=111, Expect=1e-26]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [RH, Score=115, Expect=7e-28]} {Dmel: FBgn0038126, CG8483, [Score=95.1, Expect=2e-21]} {Celegans: WBGene00011462, vap-2, Venom-Allergen-like Protein, [RH, Score=85.5, Expect=3e-18]} {Smed: dd_Smed_v6_2512_0_1, dd_Smed_v6_2512_0_1, [Score=140, Expect=2e-39]} {RNA1509_36129, RNA1509_46021, RNA1509_5027} {RNA1310_1356.1, RNA1509_36129, RNA1509_46021} {RNA1509_36129, RNA1509_46021, RNA815_4508}
36. MligTC455_34525 52 1.08 Mlig455_021566

Neo: -

Age: Down-Up-Down

 GNAI1 4.295 0.953 - 0.826 0.891 0.827 0.798 Mlig455_021566 {REF} {Length: 3532} {Pfam: G-protein alpha subunit [PF00503.22, score=404.9]; ADP-ribosylation factor family [PF00025.23, score=56.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=20.1]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.4]} {Human: ENSG00000127955, GNAI1, G protein subunit alpha i1, [Score=486, Expect=2e-171]; ENSG00000114353, GNAI2, G protein subunit alpha i2, [Score=481, Expect=3e-169]; ENSG00000065135, GNAI3, G protein subunit alpha i3, [Score=474, Expect=1e-166]} {Mouse: ENSMUSG00000057614, Gnai1, guanine nucleotide binding protein (G protein), alpha inhibiting 1, [Score=486, Expect=2e-171]; ENSMUSG00000032562, Gnai2, guanine nucleotide binding protein (G protein), alpha inhibiting 2, [Score=475, Expect=5e-167]; ENSMUSG00000000001, Gnai3, guanine nucleotide binding protein (G protein), alpha inhibiting 3, [Score=474, Expect=1e-166]} {Dmel: FBgn0001104, Galphai, G protein alpha i subunit, [Score=468, Expect=2e-164]} {Celegans: WBGene00001648, goa-1, Guanine nucleotide-binding protein G(o) subunit alpha, [Score=446, Expect=5e-156]} {Smed: dd_Smed_v6_12112_0_1, dd_Smed_v6_12112_0_1, [RH, Score=598, Expect=0.0]} {RNA1509_45426} {RNA1310_26920, RNA1509_45426} {RNA1509_45426, RNA815_11718}
37. MligTC455_18333 273 5.7 Mlig455_010935

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.059/0.00307

 4.291 0.940 0.801 - 0.877 0.965 0.708 Mlig455_010935 {REF} {Length: 510} {RNA1310_33328.2} {RNA815_15093.1}
38. MligTC455_29586 237 4.95 Mlig455_024687, Mlig455_024712

Neo: -

Age: -

Region-specific R2: 5.384

Region-enriched R2: 6.584/0.00000

 4.283 0.773 0.772 0.901 0.854 0.983 -

Mlig455_024687 {REF} {Length: 1636} {RNA1509_26262} {RNA1310_30838} {RNA815_35621}

Mlig455_024712 {REF} {Length: 1612} {RNA1509_26262} {RNA1310_30838} {RNA815_35621}
39. MligTC455_49073 824 17.17 Mlig455_063174

Neo: -

Age: Down-Down-Up

Region-specific R2: 4.151

Region-enriched R2: 3.105/0.00023
Region-enriched R4: 2.141/0.03568
Region-enriched R3: 2.031/0.03195

 4.274 0.886 0.782 0.856 0.967 0.783 - Mlig455_063174 {REF} {Length: 1083} {RNA1509_9056} {RNA1310_56777} {RNA815_24608}
40. MligTC455_44120 125 2.61 Mlig455_041513

Neo: -

Age: Up-Down-Down

Region-enriched R2: 7.169/0.00020

 4.27 - 0.741 0.879 0.831 0.971 0.848 Mlig455_041513 {REF} {Length: 644} {NoTransDecoderORF} {RNA1310_39164} {RNA815_4344}
41. MligTC455_20350 434 9.05 Mlig455_002780, Mlig455_066934

Neo: -

Age: -

Region-enriched R2: 3.513/0.00619

 SYT12 4.268 0.711 - 0.857 0.960 0.927 0.813

Mlig455_002780 {REF} {Length: 2380} {Pfam: C2 domain [PF00168.32, score=69.7]} {Human: ENSG00000173227, SYT12, synaptotagmin 12, [Score=214, Expect=3e-64]} {Mouse: ENSMUSG00000049303, Syt12, synaptotagmin XII, [Score=207, Expect=1e-61]} {Dmel: FBgn0261085, Syt12, Synaptotagmin 12, [Score=182, Expect=3e-50]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=142, Expect=2e-37]} {Smed: dd_Smed_v6_8032_0_1, dd_Smed_v6_8032_0_1, [Score=234, Expect=3e-72]} {RNA1310_10982.1} {RNA815_10652.1}

Mlig455_066934 {REF} {Length: 2274} {Pfam: C2 domain [PF00168.32, score=69.7]} {Human: ENSG00000173227, SYT12, synaptotagmin 12, [Score=214, Expect=3e-64]} {Mouse: ENSMUSG00000049303, Syt12, synaptotagmin XII, [Score=206, Expect=1e-61]} {Dmel: FBgn0261085, Syt12, Synaptotagmin 12, [Score=182, Expect=3e-50]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=142, Expect=2e-37]} {Smed: dd_Smed_v6_8032_0_1, dd_Smed_v6_8032_0_1, [Score=234, Expect=2e-72]} {RNA1310_10982.1} {RNA815_10652.1}
42. MligTC455_30463 95 1.98 Mlig455_000250, Mlig455_058521, Mlig455_058532

Neo: -

Age: -

 4.267 0.828 - 0.819 0.851 0.951 0.818

Mlig455_000250 {REF} {Length: 1994} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=19.7]} {RNA1310_59451} {RNA815_40085}

Mlig455_058521 {REF} {Length: 1237} {RNA1310_56656} {RNA815_40085}

Mlig455_058532 {REF} {Length: 1973} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=19.5]} {RNA1310_59451} {RNA815_40085}
43. MligTC455_30160 55 1.15 Mlig455_035128

Neo: -

Age: -

Region-enriched R2: 5.270/0.01686

 TCF7L1 4.258 0.896 0.801 - 0.797 0.971 0.793 Mlig455_035128 {REF} {Length: 2946} {Pfam: HMG (high mobility group) box [PF00505.21, score=79.2]; HMG-box domain [PF09011.12, score=34.5]} {Human: ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=161, Expect=1e-42]; ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=158, Expect=7e-43]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=156, Expect=2e-41]} {Mouse: ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=161, Expect=8e-43]; ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=158, Expect=9e-44]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=155, Expect=1e-42]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=156, Expect=1e-40]} {Celegans: WBGene00004077, pop-1, [Score=108, Expect=2e-25]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=166, Expect=6e-48]} {RNA1509_46571} {RNA1310_11181} {RNA815_36690}
44. MligTC455_14898 41 0.86 Mlig455_011988

Neo: -

Age: -

 4.242 0.914 - 0.829 0.730 0.950 0.819 Mlig455_011988 {REF} {Length: 858} {Pfam: Lectin C-type domain [PF00059.23, score=28.2]} {RNA1509_20946} {RNA1310_48952} {RNA815_4785.1}
45. MligTC455_17218 37 0.78 Mlig455_053853

Neo: -

Age: -

 4.24 0.969 - 0.741 0.845 0.866 0.819 Mlig455_053853 {REF} {Length: 1743} {RNA1310_61921}
46. MligTC455_49824 466 9.71 Mlig455_036536

Neo: -

Age: -

Region-specific R2: 4.841

Region-enriched R2: 3.862/0.00010

 4.237 - 0.736 0.782 0.905 0.976 0.838 Mlig455_036536 {REF} {Length: 1139} {Pfam: Nucleoporin FG repeat region [PF13634.8, score=21.2]} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [RH, Score=49.3, Expect=7e-08]} {RNA1509_18714, RNA1509_59524} {RNA1310_41906, RNA1509_18714, RNA1509_59524} {RNA1509_18714, RNA1509_59524, RNA815_24488}
47. MligTC455_02855 144 3 Mlig455_000237

Neo: -

Age: -

 B3GALT2 4.226 - 0.768 0.723 0.955 0.886 0.894 Mlig455_000237 {REF} {Length: 757} {Pfam: Galactosyltransferase [PF01762.23, score=48.0]} {Human: ENSG00000162630, B3GALT2, beta-1,3-galactosyltransferase 2, [Score=48.5, Expect=8e-07]} {Mouse: ENSMUSG00000033849, B3galt2, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2, [Score=48.5, Expect=6e-07]} {Dmel: FBgn0035558, CG11357, [Score=61.6, Expect=1e-11]} {Smed: dd_Smed_v6_4748_0_1, dd_Smed_v6_4748_0_1, [Score=88.2, Expect=2e-21]} {RNA1509_17403} {RNA1310_48383} {RNA815_28728}
48. MligTC455_29914 44 0.91 Mlig455_027923

Neo: -

Age: Down-Up-Down

Region-enriched R2: 8.096/0.00455

 ANGPTL3 4.223 0.961 - 0.819 0.786 0.803 0.854 Mlig455_027923 {REF} {Length: 1663} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=70.5]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=60.5, Expect=9e-10]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=59.3, Expect=2e-09]; ENSG00000120332, TNN, tenascin N, [Score=58.9, Expect=3e-09]} {Mouse: ENSMUSG00000015829, Tnr, tenascin R, [Score=62.4, Expect=2e-10]} {Dmel: FBgn0031804, CG9500, [Score=76.3, Expect=6e-16]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=51.2, Expect=3e-07]} {RNA1509_53291} {RNA1310_58974} {RNA815_43288.3}
49. MligTC455_38949 105 2.19 Mlig455_065209

Neo: -

Age: -

Region-specific R2: 7.633

Region-enriched R2: 10.088/0.00000

 4.213 0.952 - 0.764 0.878 0.799 0.820 Mlig455_065209 {REF} {Length: 591} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=23.2]} {RNA1509_44618} {RNA1310_63839, RNA1509_44618} {RNA1509_44618, RNA815_35329}
50. MligTC455_45912 1103 22.98 Mlig455_006912

Neo: -

Age: -

Region-specific R2: 3.366

Region-enriched R2: 1.790/0.00307

 4.21 0.822 - 0.742 0.908 0.965 0.773 Mlig455_006912 {REF} {Length: 1066} {RNA1509_32903, RNA1509_42927} {RNA1310_38334, RNA1509_42927} {RNA1509_42927, RNA815_18393}
51. MligTC455_10953 148 3.08 Mlig455_060864, Mlig455_063528

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.497/0.01237
Region-enriched R5: 3.064/0.03185

 KCNH7 4.206 0.824 0.769 0.784 0.837 0.992 -

Mlig455_060864 {REF} {Length: 7144} {Pfam: Ion transport protein [PF00520.33, score=117.5]; Cyclic nucleotide-binding domain [PF00027.31, score=52.7]; Ion channel [PF07885.18, score=45.4]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=777, Expect=0.0]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=760, Expect=0.0]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=751, Expect=0.0]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=776, Expect=0.0]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=761, Expect=0.0]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=751, Expect=0.0]} {Dmel: FBgn0003353, sei, seizure, [Score=741, Expect=0.0]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=712, Expect=0.0]} {Smed: dd_Smed_v6_12621_0_1, dd_Smed_v6_12621_0_1, [Score=798, Expect=0.0]} {RNA1509_40124} {RNA1310_4074} {RNA815_8044}

Mlig455_063528 {REF} {Length: 734} {NoTransDecoderORF}
52. MligTC455_40340 201 4.19 Mlig455_021026, Mlig455_021062

Neo: -

Age: -

 4.202 0.836 0.724 0.763 0.913 0.966 -

Mlig455_021026 {REF} {Length: 1609} {RNA1310_21018} {RNA815_22069}

Mlig455_021062 {REF} {Length: 1582} {RNA1310_21018} {RNA815_22069}
53. MligTC455_29119 68 1.42 Mlig455_050458

Neo: -

Age: -

Region-enriched R2: 5.525/0.01281

 4.2 0.956 - 0.766 0.820 0.828 0.830 Mlig455_050458 {REF} {Length: 624} {RNA1509_53840} {RNA1310_67192} {RNA815_27042}
54. MligTC455_38942 10049 209.36 Mlig455_006199, Mlig455_059287, Mlig455_065208

Neo: -

Age: Down-Up-Up

Region-specific R2: 3.098

Region-enriched R2: 2.386/0.00000

Regeneration-downregulated BL: -1.590

Regeneration-depleted BL: -1.590

 4.182 - 0.750 0.757 0.897 0.957 0.821

Mlig455_006199 {REF} {Length: 1471} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.5]; PBCV-specific basic adaptor domain [PF08789.12, score=19.4]} {RNA1509_46453} {RNA1310_48530} {RNA815_23319.1}

Mlig455_059287 {REF} {Length: 4862} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=25.9]} {RNA1509_58881} {RNA1310_67941, RNA1509_58881} {RNA1509_58881, RNA815_23357}

Mlig455_065208 {REF} {Length: 981} {Pfam: Pheromone biosynthesis activating neuropeptide (PBAN) [PF05874.13, score=24.3]} {RNA1509_18071, RNA1509_58881} {RNA1310_48530, RNA1509_18071} {RNA1509_18071, RNA815_23319.1}
55. MligTC455_22323 68 1.42 Mlig455_000713, Mlig455_000766

Neo: -

Age: -

 HCN4 4.159 0.885 - 0.786 0.776 0.952 0.760

Mlig455_000713 {REF} {Length: 3555} {Pfam: Ion transport protein N-terminal [PF08412.12, score=83.6]; Cyclic nucleotide-binding domain [PF00027.31, score=70.8]; Ion transport protein [PF00520.33, score=62.7]} {Human: ENSG00000138622, HCN4, hyperpolarization activated cyclic nucleotide gated potassium channel 4, [Score=581, Expect=0.0]; ENSG00000099822, HCN2, hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2, [Score=568, Expect=0.0]} {Mouse: ENSMUSG00000032338, Hcn4, hyperpolarization-activated, cyclic nucleotide-gated K+ 4, [Score=579, Expect=0.0]; ENSMUSG00000020331, Hcn2, hyperpolarization-activated, cyclic nucleotide-gated K+ 2, [Score=563, Expect=0.0]} {Dmel: FBgn0263397, Ih, I[[h]] channel, [RH, Score=512, Expect=1e-161]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [Score=133, Expect=8e-32]} {Smed: dd_Smed_v6_16523_0_1, dd_Smed_v6_16523_0_1, [Score=859, Expect=0.0]} {RNA1509_59211} {RNA1310_33761} {RNA815_15561.1}

Mlig455_000766 {REF} {Length: 4037} {Pfam: Ion transport protein N-terminal [PF08412.12, score=83.5]; Cyclic nucleotide-binding domain [PF00027.31, score=70.7]; Ion transport protein [PF00520.33, score=62.6]} {Human: ENSG00000138622, HCN4, hyperpolarization activated cyclic nucleotide gated potassium channel 4, [Score=566, Expect=0.0]; ENSG00000099822, HCN2, hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2, [Score=553, Expect=0.0]} {Mouse: ENSMUSG00000032338, Hcn4, hyperpolarization-activated, cyclic nucleotide-gated K+ 4, [Score=564, Expect=0.0]; ENSMUSG00000020331, Hcn2, hyperpolarization-activated, cyclic nucleotide-gated K+ 2, [Score=548, Expect=3e-180]} {Dmel: FBgn0263397, Ih, I[[h]] channel, [Score=502, Expect=4e-166]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [Score=133, Expect=8e-32]} {Smed: dd_Smed_v6_16523_0_1, dd_Smed_v6_16523_0_1, [Score=844, Expect=0.0]} {RNA1509_59211} {RNA1310_33761} {RNA815_15561.1}
56. MligTC455_50750 137 2.86 Mlig455_004587

Neo: -

Age: -

 GNB5 4.159 0.847 0.761 0.824 - 0.762 0.965 Mlig455_004587 {REF} {Length: 6245} {Pfam: WD domain, G-beta repeat [PF00400.34, score=96.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=48.4]; Eukaryotic translation initiation factor eIF2A [PF08662.13, score=26.3]; WD40-like domain [PF17005.7, score=24.1]} {Human: ENSG00000069966, GNB5, G protein subunit beta 5, [Score=411, Expect=2e-144]} {Mouse: ENSMUSG00000032192, Gnb5, guanine nucleotide binding protein (G protein), beta 5, [Score=412, Expect=9e-145]} {Dmel: FBgn0030011, Gbeta5, [Score=430, Expect=4e-152]} {Celegans: WBGene00001680, gpb-2, Guanine nucleotide-binding protein subunit beta-2, [Score=402, Expect=6e-141]} {Smed: dd_Smed_v6_10481_0_1, dd_Smed_v6_10481_0_1, [Score=476, Expect=9e-171]} {RNA1509_51468} {RNA1310_13844.1} {RNA815_14582}
57. MligTC455_19449 235 4.9 Mlig455_048896

Neo: -

Age: logFC(26M/2M)=-0.470

Region-enriched R2: 3.185/0.00006

 4.122 0.899 - 0.803 0.971 0.724 0.725 Mlig455_048896 {REF} {Length: 1819} {Pfam: Innexin [PF00876.20, score=25.6]} {RNA1509_47060} {RNA1310_19756.1, RNA1509_47060} {RNA1509_47060, RNA815_16217}
58. MligTC455_46517 122 2.54 Mlig455_051299

Neo: -

Age: -

Region-enriched R2: 3.450/0.03846

 ERC2 4.031 0.801 - 0.734 0.956 0.765 0.775 Mlig455_051299 {REF} {Length: 6303} {TRANSSPLICED} {Pfam: RIM-binding protein of the cytomatrix active zone [PF10174.11, score=167.4]; Tropomyosin like [PF12718.9, score=22.2]; Autophagy protein 16 (ATG16) [PF08614.13, score=20.7]} {Human: ENSG00000187672, ERC2, ELKS/RAB6-interacting/CAST family member 2, [Score=143, Expect=1e-33]} {Mouse: ENSMUSG00000040640, Erc2, ELKS/RAB6-interacting/CAST family member 2, [Score=143, Expect=6e-34]} {Dmel: FBgn0259246, brp, bruchpilot, [Score=117, Expect=1e-25]} {Smed: dd_Smed_v6_12278_0_1, dd_Smed_v6_12278_0_1, [Score=211, Expect=9e-55]} {RNA1509_45174, RNA1509_45537} {RNA1310_5220.1, RNA1509_45537} {RNA1509_45537, RNA815_13350}
59. MligTC455_48714 132 2.74 Mlig455_037041

Neo: -

Age: -

Region-enriched R2: 4.531/0.00493

 3.975 0.879 - 0.723 0.700 0.956 0.717 Mlig455_037041 {REF} {Length: 1099} {RNA1509_35038} {RNA1310_72135} {RNA815_37404}
60. MligTC455_50362 295 6.16 Mlig455_012011

Neo: -

Age: logFC(26M/2M)=1.080

Region-enriched R2: 3.396/0.00236

 3.961 0.764 - 0.701 0.964 0.755 0.777 Mlig455_012011 {REF} {Length: 947} {RNA1509_58656} {RNA1310_57201.1} {RNA815_30531.1}
61. MligTC455_54305 43 0.89 Mlig455_035878, Mlig455_035917

Neo: -

Age: -

 ZC3H10 3.712 0.928 - 0.860 0.977 0.947 -

Mlig455_035878 {REF} {Length: 2474} {tRNA: Val(CAC),pseudo, score=28.9} {Pfam: Zinc finger C-x8-C-x5-C-x3-H type (and similar) [PF00642.26, score=25.6]; CCCH-type zinc finger [PF18044.3, score=20.1]; Zinc-finger containing family [PF15663.7, score=19.3]; Mediator complex subunit 3 fungal [PF11593.10, score=18.0]} {Human: ENSG00000135482, ZC3H10, zinc finger CCCH-type containing 10, [Score=149, Expect=2e-40]} {Mouse: ENSMUSG00000039810, Zc3h10, zinc finger CCCH type containing 10, [Score=149, Expect=2e-40]} {Smed: dd_Smed_v6_7175_0_2, dd_Smed_v6_7175_0_2, [Score=119, Expect=4e-29]} {RNA1509_47157} {RNA1310_87786} {RNA815_46414}

Mlig455_035917 {REF} {Length: 2428} {tRNA: Val(CAC),pseudo, score=30.2} {Pfam: Zinc finger C-x8-C-x5-C-x3-H type (and similar) [PF00642.26, score=25.6]; CCCH-type zinc finger [PF18044.3, score=20.1]; Zinc-finger containing family [PF15663.7, score=19.3]; Mediator complex subunit 3 fungal [PF11593.10, score=18.0]} {Human: ENSG00000135482, ZC3H10, zinc finger CCCH-type containing 10, [Score=149, Expect=2e-40]} {Mouse: ENSMUSG00000039810, Zc3h10, zinc finger CCCH type containing 10, [Score=149, Expect=2e-40]} {Smed: dd_Smed_v6_7175_0_2, dd_Smed_v6_7175_0_2, [Score=119, Expect=4e-29]} {RNA1509_47157} {RNA1310_87786} {RNA815_46414}
62. MligTC455_10228 50 1.05 Mlig455_023553

Neo: -

Age: -

 3.704 0.955 0.906 - 0.893 0.950 - Mlig455_023553 {REF} {Length: 1195} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=20.0]} {RNA1310_22533.1} {RNA815_23050}
63. MligTC455_10226 119 2.48 Mlig455_023508, Mlig455_023518, Mlig455_023617

Neo: -

Age: -

 3.699 0.960 0.906 - 0.883 0.950 -

Mlig455_023508 {REF} {Length: 1311} {RNA1310_22533.2} {RNA815_23050}

Mlig455_023518 {REF} {Length: 1413} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=21.5]} {RNA1310_22533.2} {RNA815_23050}

Mlig455_023617 {REF} {Length: 1414} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=19.6]} {RNA1310_22533.2} {RNA815_23050}
64. MligTC455_09510 314 6.55 Mlig455_001134, Mlig455_042048

Neo: -

Age: -

Region-specific R2: 5.291

Region-enriched R2: 5.151/0.00029

 3.694 0.939 - 0.905 0.900 0.950 -

Mlig455_001134 {REF} {Length: 485} {Pfam: Fingers domain of DNA polymerase lambda [PF10391.11, score=26.9]} {RNA1310_8738.1} {RNA815_21682.1}

Mlig455_042048 {REF} {Length: 1550} {Pfam: Fingers domain of DNA polymerase lambda [PF10391.11, score=32.1]} {Dmel: FBgn0036416, CG7924, [RH, Score=61.2, Expect=1e-10]} {RNA1509_51261} {RNA1310_8738.1} {RNA815_21682.1}
65. MligTC455_41854 80 1.67 Mlig455_034307, Mlig455_067305, Mlig455_067321

Neo: -

Age: -

 3.681 0.959 0.849 - 0.923 0.950 -

Mlig455_034307 {REF} {Length: 459} {RNA815_51696.1}

Mlig455_067305 {REF} {Length: 466} {RNA815_51696.1}

Mlig455_067321 {REF} {Length: 95} {TRANSSPLICED} {NoTransDecoderORF} {RNA815_51696.1}
66. MligTC455_16329 1019 21.23 Mlig455_007993

Neo: -

Age: -

Region-specific R2: 3.685

Region-enriched R2: 3.576/0.00000
Region-enriched R7: 1.704/0.00652

 3.67 - - 0.845 0.957 0.962 0.906 Mlig455_007993 {REF} {Length: 635} {RNA1509_22236} {RNA1310_84275, RNA1509_22236} {RNA1509_22236, RNA815_43046}
67. MligTC455_40040 365 7.61 Mlig455_008332

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.784

Region-specific R2: 6.834

Region-enriched R2: 5.705/0.00005

 3.667 0.962 0.914 - 0.836 0.955 - Mlig455_008332 {REF} {Length: 707} {RNA1509_39735} {RNA1310_73916, RNA1509_39735} {RNA1509_39735, RNA815_42730.2}
68. MligTC455_27678 355 7.4 Mlig455_070610

Neo: -

Age: -

Region-specific R2: 4.724

Region-enriched R2: 3.766/0.00062

 3.657 - 0.925 0.816 0.972 0.944 - Mlig455_070610 {REF} {Length: 725} {RNA1509_17468, RNA1509_34237} {RNA1310_59474, RNA1509_17468, RNA1509_34237} {RNA1509_17468, RNA1509_34237, RNA815_28024}
69. MligTC455_23220 56 1.18 Mlig455_060190

Neo: -

Age: -

 ACKR3 3.652 - 0.901 0.889 0.894 0.968 - Mlig455_060190 {REF} {Length: 2108} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=106.0]} {Human: ENSG00000144476, ACKR3, atypical chemokine receptor 3, [RH, Score=99.0, Expect=1e-22]} {Mouse: ENSMUSG00000026180, Cxcr2, chemokine (C-X-C motif) receptor 2, [Score=112, Expect=1e-27]} {Dmel: FBgn0266429, AstA-R1, Allatostatin A receptor 1, [Score=102, Expect=4e-24]} {Celegans: WBGene00021439, ckr-2, CholecystoKinin Receptor homolog; Cholecystokinin receptor 2 splice isoform b, [Score=68.2, Expect=2e-12]} {Smed: dd_Smed_v6_10325_0_1, dd_Smed_v6_10325_0_1, [Score=81.6, Expect=5e-17]} {RNA1310_66504} {RNA815_39432}
70. MligTC455_18748 104 2.17 Mlig455_024985, Mlig455_024999

Neo: -

Age: -

Region-enriched R2: 6.002/0.00016
Region-enriched R4: 3.433/0.02745

 GRIK4 3.623 0.961 - - 0.866 0.985 0.811

Mlig455_024985 {REF} {Length: 1514} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_47299} {RNA815_38321}

Mlig455_024999 {REF} {Length: 3567} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_7578, RNA1509_35538} {RNA1509_35538, RNA815_4987}
71. MligTC455_48604 173 3.6 Mlig455_031074

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.490

 3.619 0.940 0.852 - 0.867 0.960 - Mlig455_031074 {REF} {Length: 652} {RNA1310_66509}
72. MligTC455_50778 36 0.76 Mlig455_042296

Neo: -

Age: -

 GPR50 3.615 - - 0.840 0.969 0.985 0.821 Mlig455_042296 {REF} {Length: 1415} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=116.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=40.0]; Olfactory receptor [PF13853.8, score=34.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=33.9]} {Human: ENSG00000102195, GPR50, G protein-coupled receptor 50, [Score=124, Expect=4e-31]; ENSG00000134640, MTNR1B, melatonin receptor 1B, [Score=119, Expect=2e-30]} {Mouse: ENSMUSG00000054764, Mtnr1a, melatonin receptor 1A, [Score=120, Expect=4e-31]; ENSMUSG00000056380, Gpr50, G-protein-coupled receptor 50, [Score=119, Expect=2e-29]; ENSMUSG00000050901, Mtnr1b, melatonin receptor 1B, [Score=118, Expect=5e-30]} {Dmel: FBgn0038980, Octbeta1R, Octopamine beta1 receptor, [Score=92.0, Expect=1e-20]} {Celegans: WBGene00006428, tkr-3, TachyKinin Receptor family, [Score=69.7, Expect=4e-13]} {Smed: dd_Smed_v6_65999_0_1, dd_Smed_v6_65999_0_1, [Score=84.7, Expect=1e-18]} {RNA1310_66047} {RNA815_34066}
73. MligTC455_50777 40 0.83 Mlig455_042072

Neo: -

Age: -

 MTNR1B 3.611 - - 0.855 0.967 0.984 0.805 Mlig455_042072 {REF} {Length: 2881} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=78.0]; Olfactory receptor [PF13853.8, score=24.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=22.0]} {Human: ENSG00000134640, MTNR1B, melatonin receptor 1B, [Score=94.4, Expect=2e-21]; ENSG00000168412, MTNR1A, melatonin receptor 1A, [Score=90.1, Expect=5e-20]} {Mouse: ENSMUSG00000050901, Mtnr1b, melatonin receptor 1B, [Score=94.0, Expect=2e-21]; ENSMUSG00000054764, Mtnr1a, melatonin receptor 1A, [Score=89.4, Expect=6e-20]} {Dmel: FBgn0004514, Oct-TyrR, Octopamine-Tyramine receptor, [Score=57.0, Expect=7e-09]} {Celegans: WBGene00006428, tkr-3, TachyKinin Receptor family, [Score=52.0, Expect=2e-07]} {Smed: dd_Smed_v6_19535_0_1, dd_Smed_v6_19535_0_1, [Score=95.5, Expect=2e-22]} {RNA1310_66047} {RNA815_34066}
74. MligTC455_32392 63 1.31 Mlig455_048146

Neo: -

Age: -

 SDCBP2 3.596 - 0.790 0.888 0.965 0.953 - Mlig455_048146 {REF} {Length: 895} {Pfam: PDZ domain [PF00595.26, score=47.3]; PDZ domain [PF17820.3, score=35.5]; PDZ domain [PF13180.8, score=31.4]} {Human: ENSG00000125775, SDCBP2, syndecan binding protein 2, [Score=60.1, Expect=1e-10]} {Mouse: ENSMUSG00000027456, Sdcbp2, syndecan binding protein (syntenin) 2, [Score=61.2, Expect=3e-11]} {Dmel: FBgn0263289, scrib, scribbled, [Score=46.6, Expect=4e-06]} {Celegans: WBGene00016678, C45G9.7, [Score=44.3, Expect=4e-06]} {Smed: dd_Smed_v6_11951_0_1, dd_Smed_v6_11951_0_1, [Score=90.5, Expect=1e-21]} {RNA1310_28491} {RNA815_52955}
75. MligTC455_50927 254 5.29 Mlig455_070541, Mlig455_070562

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.296

Region-enriched R2: 7.883/0.00008
Region-enriched R3: 4.441/0.03979

 FZD4 3.587 - - 0.834 0.957 0.951 0.845

Mlig455_070541 {REF} {Length: 3522} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=471, Expect=6e-159]} {RNA1509_15834} {RNA1310_3800, RNA1509_15834} {RNA1509_15834, RNA815_19571}

Mlig455_070562 {REF} {Length: 3527} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=2e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=470, Expect=8e-159]} {RNA1509_15834} {RNA1310_3800} {RNA815_19571}
76. MligTC455_44025 591 12.31 Mlig455_050980

Neo: -

Age: -

Region-specific R2: 5.366

Region-enriched R2: 5.986/0.00000

 3.585 0.888 - 0.834 0.905 0.958 - Mlig455_050980 {REF} {Length: 587} {Smed: dd_Smed_v6_2575_0_1, dd_Smed_v6_2575_0_1, [Score=49.7, Expect=7e-09]} {RNA1509_52032} {RNA1310_52449.2} {RNA815_56904}
77. MligTC455_34987 27 0.56 Mlig455_031823, Mlig455_047624, Mlig455_047675

Neo: -

Age: -

 KREMEN2 3.583 - 0.878 0.814 0.940 0.951 -

Mlig455_031823 {REF} {Length: 873} {Pfam: WSC domain [PF01822.21, score=52.7]; PAN domain [PF00024.28, score=21.9]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.4, Expect=2e-07]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=50.4, Expect=4e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=60.1, Expect=2e-10]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=47.8, Expect=2e-06]} {RNA1509_53783} {RNA1310_52135.1} {RNA815_24434}

Mlig455_047624 {REF} {Length: 824} {Pfam: WSC domain [PF01822.21, score=55.0]; PAN domain [PF00024.28, score=22.2]; PAN domain [PF14295.8, score=19.1]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=56.2, Expect=5e-09]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=63.5, Expect=1e-11]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=49.7, Expect=4e-07]} {RNA1509_53783} {RNA1310_52135.1} {RNA815_24434}

Mlig455_047675 {REF} {Length: 2718} {Pfam: WSC domain [PF01822.21, score=53.8]; PAN domain [PF00024.28, score=21.8]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=56.2, Expect=6e-09]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=65.5, Expect=4e-12]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=49.7, Expect=6e-07]} {RNA1509_53783} {RNA1310_52135.1} {RNA815_24434}
78. MligTC455_26519 183 3.82 Mlig455_030983, Mlig455_069440

Neo: -

Age: -

 3.567 0.886 - 0.794 0.897 0.990 -

Mlig455_030983 {REF} {Length: 688} {RNA1509_12904} {RNA1310_62229} {RNA815_56172}

Mlig455_069440 {REF} {Length: 1096} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=54.9]} {RNA1509_35362} {RNA1310_21423.2} {RNA815_13686}
79. MligTC455_33280 127 2.64 Mlig455_010523

Neo: -

Age: Down-Up-Up

 3.566 0.950 - 0.909 0.960 0.747 - Mlig455_010523 {REF} {Length: 587} {RNA1509_48963} {RNA1310_65789} {RNA815_23468}
80. MligTC455_26356 62 1.3 Mlig455_042551

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.548

 GRIK2 3.563 0.947 - - 0.814 0.983 0.819 Mlig455_042551 {REF} {Length: 2917} {Pfam: Ligand-gated ion channel [PF00060.28, score=82.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=60.7]; Receptor family ligand binding region [PF01094.30, score=32.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=27.3]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=144, Expect=9e-35]; ENSG00000152208, GRID2, glutamate ionotropic receptor delta type subunit 2, [Score=141, Expect=7e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=143, Expect=1e-34]; ENSMUSG00000071424, Grid2, glutamate receptor, ionotropic, delta 2, [Score=142, Expect=2e-34]} {Dmel: FBgn0051201, GluRIIE, Glutamate receptor IIE, [Score=119, Expect=3e-27]} {Celegans: WBGene00001616, glr-5, GLutamate Receptor family (AMPA), [Score=123, Expect=2e-28]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=247, Expect=4e-74]} {RNA1310_21865} {RNA815_26044}
81. MligTC455_44999 2214 46.12 Mlig455_067394, Mlig455_069538

Neo: -

Age: Down-Up-Up

Region-enriched R2: 2.840/0.00027

 3.558 - - 0.883 0.960 0.926 0.789

Mlig455_067394 {REF} {Length: 401} {RNA1509_52966} {RNA1310_68651, RNA1509_52966} {RNA1509_52966, RNA815_33112.1}

Mlig455_069538 {REF} {Length: 1759} {Celegans: WBGene00001446, flp-3, FMRFamide-like neuropeptides 3 SPLGTMRF-amide TPLGTMRF-amide SAEPFGTMRF-amide NPENDTPFGTMRF-amide ASEDALFGTMRF-amide EAEEPLGTMRF-amide SADDSAPFGTMRF-amide NPLGTMRF-amide, [Score=45.8, Expect=1e-06]} {RNA1509_13671} {RNA1310_56061} {RNA815_33112.1}
82. MligTC455_16358 1175 24.47 Mlig455_039878

Neo: -

Age: -

Region-specific R2: 4.659

Region-enriched R2: 4.310/0.00000

 3.542 0.855 - 0.868 0.869 0.950 - Mlig455_039878 {REF} {Length: 1188} {RNA1509_60020} {RNA1310_35099.1, RNA1509_60020} {RNA1509_60020, RNA815_1356.1}
83. MligTC455_25701 31 0.65 Mlig455_017477

Neo: -

Age: -

 3.542 0.945 - 0.758 0.870 0.969 - Mlig455_017477 {REF} {Length: 664} {RNA1310_52753} {RNA815_26527}
84. MligTC455_53415 319 6.64 Mlig455_053444

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.862

Region-enriched R2: 4.179/0.00011

 RP1 3.539 - - 0.866 0.859 0.953 0.861 Mlig455_053444 {REF} {Length: 4944} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.3]; Doublecortin [PF03607.19, score=100.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.5]; Fibroblast growth factor [PF00167.20, score=18.6]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=471, Expect=6e-145]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=453, Expect=3e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.9, Expect=1e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=691, Expect=0.0]} {RNA1509_59703} {RNA1310_2710} {RNA815_17469}
85. MligTC455_25072 4443 92.56 Mlig455_015899

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.175

Region-enriched R2: 4.389/0.00000

 PI16 3.537 - 0.798 - 0.952 0.921 0.866 Mlig455_015899 {REF} {Length: 2017} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=71.8]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=112, Expect=1e-26]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [RH, Score=115, Expect=5e-28]} {Dmel: FBgn0038126, CG8483, [Score=95.5, Expect=2e-21]} {Celegans: WBGene00011462, vap-2, Venom-Allergen-like Protein, [RH, Score=85.5, Expect=5e-18]} {Smed: dd_Smed_v6_2512_0_1, dd_Smed_v6_2512_0_1, [Score=140, Expect=2e-39]} {RNA1509_5027} {RNA1310_1356.1} {RNA815_4508}
86. MligTC455_03110 58 1.2 Mlig455_069260

Neo: -

Age: -

 GABBR2 3.536 - 0.837 0.886 0.859 0.954 - Mlig455_069260 {REF} {Length: 6190} {TRANSSPLICED} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=150.8]; Receptor family ligand binding region [PF01094.30, score=121.6]} {Human: ENSG00000136928, GABBR2, gamma-aminobutyric acid type B receptor subunit 2, [Score=259, Expect=1e-73]} {Mouse: ENSMUSG00000039809, Gabbr2, gamma-aminobutyric acid (GABA) B receptor, 2, [Score=255, Expect=2e-72]} {Dmel: FBgn0027575, GABA-B-R2, metabotropic GABA-B receptor subtype 2, [Score=238, Expect=4e-66]} {Celegans: WBGene00021528, gbb-1, GABA B receptor subunit; GABAB1 receptor subunit, [Score=223, Expect=8e-62]} {Smed: dd_Smed_v6_59890_0_1, dd_Smed_v6_59890_0_1, [Score=112, Expect=1e-28]} {RNA1509_59815} {RNA1310_19655} {RNA815_19308}
87. MligTC455_31853 516 10.74 Mlig455_014495, Mlig455_014514, Mlig455_054434

Neo: -

Age: -

 3.528 0.928 - 0.840 - 0.964 0.796

Mlig455_014495 {REF} {Length: 3100} {RNA1509_20117} {RNA1310_5956.1, RNA1509_20117} {RNA1509_20117, RNA815_18508}

Mlig455_014514 {REF} {Length: 3051} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.7, Expect=2e-19]} {RNA1509_20117} {RNA1310_5956.1} {RNA815_18508}

Mlig455_054434 {REF} {Length: 4026} {Pfam: Late embryogenesis abundant protein [PF03242.15, score=21.0]} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.4, Expect=2e-20]} {RNA1509_20117} {RNA1310_8165} {RNA815_23492}
88. MligTC455_31163 72 1.51 Mlig455_045625

Neo: -

Age: Up-Down-Down

 3.526 0.974 - 0.755 - 0.988 0.809 Mlig455_045625 {REF} {Length: 1957} {RNA1509_21720} {RNA1310_14760, RNA1509_21720} {RNA1509_21720, RNA815_24583}
89. MligTC455_35802 114 2.38 Mlig455_051876, Mlig455_051902, Mlig455_053140

Neo: -

Age: -

 CACNA2D1 3.523 - 0.857 - 0.951 0.888 0.827

Mlig455_051876 {REF} {Length: 3144} {Pfam: Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=89.1]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=84.7, Expect=2e-16]} {RNA1509_55590} {RNA1310_60852} {RNA815_15380}

Mlig455_051902 {REF} {Length: 4662} {Pfam: VWA N-terminal [PF08399.13, score=90.4]; Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=87.6]; von Willebrand factor type A domain [PF00092.30, score=38.6]; Cache domain [PF02743.20, score=27.5]; von Willebrand factor type A domain [PF13519.8, score=26.5]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [RH, Score=326, Expect=8e-94]} {Mouse: ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [RH, Score=326, Expect=7e-94]} {Dmel: FBgn0261041, stj, straightjacket, [Score=229, Expect=7e-61]} {Celegans: WBGene00006772, unc-36, Voltage-dependent calcium channel unc-36, [Score=141, Expect=9e-34]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [Score=153, Expect=1e-37]} {RNA1509_55590} {RNA1310_7325.1, RNA1509_55590} {RNA1509_55590, RNA815_14878}

Mlig455_053140 {REF} {Length: 3265} {Pfam: Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=87.9]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=87.0, Expect=8e-17]} {Mouse: ENSMUSG00000021991, Cacna2d3, calcium channel, voltage-dependent, alpha2/delta subunit 3, [Score=50.4, Expect=9e-06]} {RNA1509_55590} {RNA1310_7325.1} {RNA815_14878}
90. MligTC455_29915 50 1.04 Mlig455_027934

Neo: -

Age: Down-Up-Up

Region-enriched R2: 6.881/0.04464

 ANGPTL1 3.521 0.964 - 0.845 - 0.867 0.845 Mlig455_027934 {REF} {Length: 2265} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=43.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=48.9, Expect=9e-06]} {Dmel: FBgn0031804, CG9500, [Score=53.1, Expect=9e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=49.7, Expect=1e-06]} {RNA1509_53291} {RNA1310_38229.1} {RNA815_10579.1}
91. MligTC455_44904 1501 31.27 Mlig455_021814

Neo: -

Age: Down-Up-Up

Region-specific R2: 3.865

Region-enriched R2: 3.792/0.00000

 3.52 - - 0.783 0.963 0.943 0.831 Mlig455_021814 {REF} {Length: 959} {RNA1509_15805} {RNA1310_67099.1, RNA1509_15805} {RNA1509_15805, RNA815_17533}
92. MligTC455_19876 135 2.82 Mlig455_024520, Mlig455_024523

Neo: -

Age: -

 3.519 - - 0.856 0.826 0.967 0.870

Mlig455_024520 {REF} {Length: 2352} {Pfam: CD20-like family [PF04103.17, score=40.9]} {Mouse: ENSMUSG00000048004, Tmem196, transmembrane protein 196, [Score=63.5, Expect=2e-12]} {Smed: dd_Smed_v6_14043_0_1, dd_Smed_v6_14043_0_1, [Score=184, Expect=5e-59]} {RNA1509_25506} {RNA1310_9338} {RNA815_23744}

Mlig455_024523 {REF} {Length: 2311} {Smed: dd_Smed_v6_14043_0_1, dd_Smed_v6_14043_0_1, [Score=153, Expect=3e-47]} {RNA1509_25506} {RNA1310_9338} {RNA815_23744}
93. MligTC455_30159 107 2.22 Mlig455_008465, Mlig455_009916

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.961/0.00498

 TCF7L1 3.516 - 0.779 - 0.902 0.983 0.852

Mlig455_008465 {REF} {Length: 2454} {Pfam: HMG (high mobility group) box [PF00505.21, score=81.3]; HMG-box domain [PF09011.12, score=34.6]} {Human: ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=161, Expect=7e-43]; ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=3e-43]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=156, Expect=8e-42]} {Mouse: ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=161, Expect=4e-43]; ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=4e-44]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=155, Expect=6e-43]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=157, Expect=4e-41]} {Celegans: WBGene00004077, pop-1, [Score=108, Expect=2e-25]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=166, Expect=2e-48]} {RNA1310_11181} {RNA815_36690}

Mlig455_009916 {REF} {Length: 2137} {Pfam: HMG (high mobility group) box [PF00505.21, score=81.4]; HMG-box domain [PF09011.12, score=34.7]} {Human: ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=161, Expect=4e-43]; ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=2e-43]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=157, Expect=5e-42]} {Mouse: ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=162, Expect=2e-43]; ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=3e-44]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=155, Expect=4e-43]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=157, Expect=3e-41]} {Celegans: WBGene00004077, pop-1, [Score=108, Expect=2e-25]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=166, Expect=1e-48]} {RNA1310_11181} {RNA815_36690}
94. MligTC455_44861 2493 51.93 Mlig455_012204, Mlig455_069065

Neo: -

Age: -

Region-specific R2: 2.926

Region-enriched R2: 2.403/0.00000

Regeneration-downregulated BL: -1.850

Regeneration-depleted BL: -1.850

 QPCT 3.516 - 0.769 0.849 0.943 0.955 -

Mlig455_012204 {REF} {Length: 1746} {Pfam: Peptidase family M28 [PF04389.19, score=139.1]} {Human: ENSG00000115828, QPCT, glutaminyl-peptide cyclotransferase, [RH, Score=186, Expect=7e-56]; ENSG00000011478, QPCTL, glutaminyl-peptide cyclotransferase like, [RH, Score=181, Expect=2e-53]} {Mouse: ENSMUSG00000030407, Qpctl, glutaminyl-peptide cyclotransferase-like, [RH, Score=184, Expect=6e-55]; ENSMUSG00000024084, Qpct, glutaminyl-peptide cyclotransferase (glutaminyl cyclase), [RH, Score=184, Expect=2e-55]} {Dmel: FBgn0036999, isoQC, iso Glutaminyl cyclase, [RH, Score=208, Expect=8e-65]} {Celegans: WBGene00010418, H27A22.1, [Score=183, Expect=2e-55]} {Smed: dd_Smed_v6_4861_0_2, dd_Smed_v6_4861_0_2, [Score=162, Expect=3e-47]} {RNA1509_15042} {RNA1310_21925} {RNA815_8635.2}

Mlig455_069065 {REF} {Length: 1718} {Pfam: Peptidase family M28 [PF04389.19, score=83.4]} {Human: ENSG00000115828, QPCT, glutaminyl-peptide cyclotransferase, [Score=133, Expect=1e-36]; ENSG00000011478, QPCTL, glutaminyl-peptide cyclotransferase like, [Score=128, Expect=1e-34]} {Mouse: ENSMUSG00000024084, Qpct, glutaminyl-peptide cyclotransferase (glutaminyl cyclase), [Score=138, Expect=1e-38]; ENSMUSG00000030407, Qpctl, glutaminyl-peptide cyclotransferase-like, [Score=135, Expect=2e-37]} {Dmel: FBgn0036999, isoQC, iso Glutaminyl cyclase, [Score=157, Expect=3e-46]} {Celegans: WBGene00010418, H27A22.1, [Score=148, Expect=9e-43]} {Smed: dd_Smed_v6_4861_0_1, dd_Smed_v6_4861_0_1, [Score=119, Expect=8e-32]} {RNA1509_15042} {RNA1310_21925} {RNA815_8635.2}
95. MligTC455_52527 28 0.58 Mlig455_025836

Neo: -

Age: -

 FLVCR2 3.515 0.872 0.884 0.787 - 0.972 - Mlig455_025836 {REF} {Length: 2177} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=81.4]; Sugar (and other) transporter [PF00083.26, score=18.7]} {Human: ENSG00000119686, FLVCR2, feline leukemia virus subgroup C cellular receptor family member 2, [RH, Score=364, Expect=5e-119]} {Mouse: ENSMUSG00000034258, Flvcr2, feline leukemia virus subgroup C cellular receptor 2, [RH, Score=367, Expect=3e-120]} {Dmel: FBgn0033196, CG1358, [RH, Score=350, Expect=1e-114]} {Celegans: WBGene00015632, C09D4.1, Uncharacterized MFS-type transporter C09D4.1, [RH, Score=358, Expect=1e-116]} {Smed: dd_Smed_v6_7578_0_1, dd_Smed_v6_7578_0_1, [Score=335, Expect=3e-109]} {RNA1509_31725} {RNA1310_8852.1} {RNA815_14234}
96. MligTC455_18099 24 0.51 Mlig455_036525

Neo: -

Age: -

 PPA1 3.51 0.945 - - 0.775 0.987 0.803 Mlig455_036525 {REF} {Length: 1911} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1310_57333.1} {RNA815_22340}
97. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

 3.498 0.945 - 0.764 - 0.970 0.819 Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
98. MligTC455_09472 23 0.47 Mlig455_059329

Neo: -

Age: -

 NGB 3.492 0.945 - - 0.954 0.796 0.797 Mlig455_059329 {REF} {Length: 2110} {Pfam: Globin [PF00042.24, score=52.9]} {Human: ENSG00000165553, NGB, neuroglobin, [RH, Score=48.5, Expect=8e-07]} {Mouse: ENSMUSG00000021032, Ngb, neuroglobin, [RH, Score=50.4, Expect=1e-07]} {RNA1310_93460} {RNA815_18392}
99. MligTC455_25921 329 6.86 Mlig455_006703

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-2.996

Region-enriched R2: 6.614/0.00492

 3.492 0.953 0.878 - 0.858 0.803 - Mlig455_006703 {REF} {Length: 664} {RNA1509_22927} {RNA1310_80445} {RNA815_41771.1}
100. MligTC455_19041 54 1.12 Mlig455_030662

Neo: -

Age: -

Region-enriched R2: 9.337/0.00002
Region-enriched R3: 6.044/0.00168

 CAV1 3.491 0.956 - 0.818 0.918 0.799 - Mlig455_030662 {REF} {Length: 940} {Pfam: Caveolin [PF01146.19, score=117.8]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=98.2, Expect=1e-26]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=99.4, Expect=3e-27]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=73.9, Expect=6e-17]} {Smed: dd_Smed_v6_6535_0_1, dd_Smed_v6_6535_0_1, [RH, Score=133, Expect=6e-41]} {RNA1509_53325} {RNA1310_97043} {RNA815_32565}

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