Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_46242 | 1273 | 26.52 | Mlig455_023425, Mlig455_023451 | Neo: - Age: - |
SMO | Mlig455_023425 {REF} {Length: 5086} {TRANSSPLICED} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=93.7]; Fz domain [PF01392.24, score=33.9]} {Human: ENSG00000128602, SMO, smoothened, frizzled class receptor, [Score=125, Expect=2e-28]} {Mouse: ENSMUSG00000001761, Smo, smoothened, frizzled class receptor, [Score=121, Expect=2e-27]} {Dmel: FBgn0003444, smo, smoothened, [Score=122, Expect=8e-28]} {RNA1509_38445, RNA1509_49220, RNA1509_7027} {RNA1310_1187.1, RNA1509_38445, RNA1509_49220, RNA1509_7027} {RNA1509_38445, RNA1509_49220, RNA1509_7027, RNA815_2620} Mlig455_023451 {REF} {Length: 5069} {TRANSSPLICED} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=93.6]; Fz domain [PF01392.24, score=33.9]} {Human: ENSG00000128602, SMO, smoothened, frizzled class receptor, [Score=126, Expect=5e-29]} {Mouse: ENSMUSG00000001761, Smo, smoothened, frizzled class receptor, [Score=122, Expect=7e-28]} {Dmel: FBgn0003444, smo, smoothened, [Score=122, Expect=9e-28]} {RNA1509_7027} {RNA1310_1187.1} {RNA815_2620} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.74 | 4.873 | 0.38014 | 1.00000 | |
RegionR2 | 0.418 | 4.873 | 0.43699 | 0.82663 | |
RegionR3 | 0.056 | 4.873 | 0.90398 | 1.00000 | |
RegionR4 | -0.729 | 4.873 | 0.18320 | 0.45476 | |
RegionR5 | 1.096 | 4.873 | 0.00996 | 0.05754 | |
RegionR6 | 0.733 | 4.873 | 0.10484 | 0.59397 | |
RegionR7 | -0.405 | 4.873 | 0.45356 | 1.00000 | |
RegionR8 | -0.429 | 4.873 | 0.48422 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -1.307 | 4.873 | 0.30832 | 1.00000 | |
RegenerationR2 | -0.709 | 4.873 | 0.23402 | 0.68152 | |
RegenerationR3 | -0.664 | 4.873 | 0.27119 | 0.70536 | |
RegenerationR4 | -0.11 | 4.873 | 0.85865 | 1.00000 | |
RegenerationR5 | -0.741 | 4.873 | 0.20006 | 0.63268 | |
RegenerationR6 | -1.284 | 4.873 | 0.03132 | 0.22123 | |
RegenerationBL | -0.463 | 4.873 | 0.42698 | 0.79530 | |
RegenerationTP | 0.507 | 4.873 | 0.41274 | 0.83876 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_46242 | 1273 | 26.52 | Mlig455_023425, Mlig455_023451 | Neo: - Age: - |
SMO | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_023425 {REF} {Length: 5086} {TRANSSPLICED} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=93.7]; Fz domain [PF01392.24, score=33.9]} {Human: ENSG00000128602, SMO, smoothened, frizzled class receptor, [Score=125, Expect=2e-28]} {Mouse: ENSMUSG00000001761, Smo, smoothened, frizzled class receptor, [Score=121, Expect=2e-27]} {Dmel: FBgn0003444, smo, smoothened, [Score=122, Expect=8e-28]} {RNA1509_38445, RNA1509_49220, RNA1509_7027} {RNA1310_1187.1, RNA1509_38445, RNA1509_49220, RNA1509_7027} {RNA1509_38445, RNA1509_49220, RNA1509_7027, RNA815_2620} Mlig455_023451 {REF} {Length: 5069} {TRANSSPLICED} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=93.6]; Fz domain [PF01392.24, score=33.9]} {Human: ENSG00000128602, SMO, smoothened, frizzled class receptor, [Score=126, Expect=5e-29]} {Mouse: ENSMUSG00000001761, Smo, smoothened, frizzled class receptor, [Score=122, Expect=7e-28]} {Dmel: FBgn0003444, smo, smoothened, [Score=122, Expect=9e-28]} {RNA1509_7027} {RNA1310_1187.1} {RNA815_2620} |
2. | MligTC455_19976 | 1008 | 21 | Mlig455_006463 | Neo: - Age: logFC(26M/2M)=-0.227 |
NGEF | 2.432 | - | - | 0.951 | - | 0.758 | 0.723 | Mlig455_006463 {REF} {Length: 5393} {Pfam: RhoGEF domain [PF00621.22, score=103.1]; SH3 domain [PF00018.30, score=45.6]; Variant SH3 domain [PF07653.19, score=43.7]; Variant SH3 domain [PF14604.8, score=38.2]} {Human: ENSG00000066248, NGEF, neuronal guanine nucleotide exchange factor, [RH, Score=226, Expect=3e-64]; ENSG00000130762, ARHGEF16, Rho guanine nucleotide exchange factor 16, [RH, Score=224, Expect=1e-62]; ENSG00000114790, ARHGEF26, Rho guanine nucleotide exchange factor 26, [RH, Score=218, Expect=9e-60]; ENSG00000277101, ARHGEF26, Rho guanine nucleotide exchange factor 26, [RH, Score=218, Expect=9e-60]} {Mouse: ENSMUSG00000026259, Ngef, neuronal guanine nucleotide exchange factor, [RH, Score=231, Expect=2e-65]} {Dmel: FBgn0261547, Exn, Ephexin, [RH, Score=214, Expect=2e-58]} {Celegans: WBGene00019487, ephx-1, EPHeXin (Eph-interacting GEF) homolog, [Score=215, Expect=2e-60]} {Smed: dd_Smed_v6_1847_0_10, dd_Smed_v6_1847_0_10, [RH, Score=184, Expect=3e-49]} {RNA1509_5926} {RNA1310_1816.1} {RNA815_898.1} |
3. | MligTC455_39652 | 1049 | 21.85 | Mlig455_036203 | Neo: - Age: Up-Up-Down Regeneration-downregulated BL: -1.979 Regeneration-depleted BL: -1.979 |
RNF217 | 1.743 | - | - | - | 0.961 | - | 0.782 | Mlig455_036203 {REF} {Length: 5439} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=50.6]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=166, Expect=1e-44]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=163, Expect=5e-44]} {Dmel: FBgn0025186, ari-2, ariadne 2, [Score=68.6, Expect=5e-12]} {Celegans: WBGene00016156, C27A12.6, [Score=72.0, Expect=3e-13]} {Smed: dd_Smed_v6_7110_0_1, dd_Smed_v6_7110_0_1, [Score=128, Expect=8e-32]} {RNA1509_19339, RNA1509_41201, RNA1509_57487} {RNA1310_11553.2, RNA1509_19339, RNA1509_41201, RNA1509_57487} {RNA1509_19339, RNA1509_41201, RNA1509_57487, RNA815_5548} |
4. | MligTC455_25802 | 373 | 7.77 | Mlig455_020238, Mlig455_040926, Mlig455_040927, Mlig455_043949 | Neo: - Age: Up-Down-Up Region-enriched R4: 2.322/0.03456 |
NYNRIN | 0.956 | - | - | - | - | - | 0.956 | Mlig455_020238 {REF} {Length: 2535} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=110.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=101.9]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=85.5]; Integrase zinc binding domain [PF17921.3, score=59.5]; Integrase core domain [PF00665.28, score=54.8]; H2C2 zinc finger [PF09337.12, score=19.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=76.6, Expect=2e-13]} {Mouse: ENSMUSG00000098639, Rtl1, retrotransposon Gaglike 1, [Score=89.7, Expect=9e-18]; ENSMUSG00000085925, Rtl1, retrotransposon Gaglike 1, [Score=89.7, Expect=9e-18]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=299, Expect=9e-88]} {RNA1509_41126} {RNA1310_3178} {RNA815_42463} Mlig455_040926 {REF} {Length: 3407} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=110.3]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=101.4]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=84.9]; Integrase zinc binding domain [PF17921.3, score=60.1]; Integrase core domain [PF00665.28, score=54.5]; gag-polyprotein putative aspartyl protease [PF13975.8, score=25.7]; H2C2 zinc finger [PF09337.12, score=23.0]; Retroviral aspartyl protease [PF00077.22, score=21.7]; Aspartyl protease [PF13650.8, score=21.3]; Integrase core domain [PF13683.8, score=20.7]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=78.2, Expect=6e-14]} {Mouse: ENSMUSG00000085925, Rtl1, retrotransposon Gaglike 1, [Score=91.3, Expect=5e-18]; ENSMUSG00000098639, Rtl1, retrotransposon Gaglike 1, [Score=91.3, Expect=5e-18]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=324, Expect=5e-95]} {RNA1509_41126} {RNA1310_3178} {RNA815_42463} Mlig455_040927 {REF} {Length: 2674} {TRANSSPLICED} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=126.2]; Endonuclease-reverse transcriptase [PF14529.8, score=76.5]} {RNA1509_32599} {RNA1310_1659} {RNA815_252.1} Mlig455_043949 {REF} {Length: 2236} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=111.4]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=102.4]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=85.1]} {Mouse: ENSMUSG00000085925, Rtl1, retrotransposon Gaglike 1, [Score=89.4, Expect=6e-18]; ENSMUSG00000098639, Rtl1, retrotransposon Gaglike 1, [Score=89.4, Expect=6e-18]} {Smed: dd_Smed_v6_1574_6_44, dd_Smed_v6_1574_6_44, [Score=249, Expect=9e-75]} {RNA1509_41126} {RNA1310_3178} {RNA815_42463} |
5. | MligTC455_34271 | 673 | 14.01 | Mlig455_025745, Mlig455_025747, Mlig455_025774 | Neo: - Age: Down-Up-Down |
USP12 | 0.955 | - | - | - | - | - | 0.955 | Mlig455_025745 {REF} {Length: 866} {Human: ENSG00000152484, USP12, ubiquitin specific peptidase 12, [Score=47.8, Expect=3e-07]; ENSG00000109189, USP46, ubiquitin specific peptidase 46, [Score=45.8, Expect=2e-06]} {Mouse: ENSMUSG00000029640, Usp12, ubiquitin specific peptidase 12, [Score=48.1, Expect=2e-07]; ENSMUSG00000054814, Usp46, ubiquitin specific peptidase 46, [Score=45.8, Expect=1e-06]} {Dmel: FBgn0039025, Usp12-46, Ubiquitin-specific protease 12/46, [Score=45.8, Expect=8e-07]} {Celegans: WBGene00011216, usp-46, Ubiquitin carboxyl-terminal hydrolase 46, [Score=46.2, Expect=5e-07]} {Smed: dd_Smed_v6_6911_0_2, dd_Smed_v6_6911_0_2, [Score=45.1, Expect=8e-07]} {RNA1509_6725} {RNA1310_9715} {RNA815_4428} Mlig455_025747 {REF} {Length: 775} {NoTransDecoderORF} {RNA1509_34917} {RNA1310_43504} {RNA815_28201} Mlig455_025774 {REF} {Length: 4536} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=211.0]; Ubiquitin carboxyl-terminal hydrolase [PF13423.8, score=91.3]} {Human: ENSG00000152484, USP12, ubiquitin specific peptidase 12, [RH, Score=468, Expect=3e-164]; ENSG00000109189, USP46, ubiquitin specific peptidase 46, [RH, Score=466, Expect=1e-163]} {Mouse: ENSMUSG00000029640, Usp12, ubiquitin specific peptidase 12, [RH, Score=472, Expect=5e-166]; ENSMUSG00000054814, Usp46, ubiquitin specific peptidase 46, [RH, Score=466, Expect=8e-164]} {Dmel: FBgn0039025, Usp12-46, Ubiquitin-specific protease 12/46, [RH, Score=457, Expect=1e-159]} {Celegans: WBGene00011216, usp-46, Ubiquitin carboxyl-terminal hydrolase 46, [RH, Score=450, Expect=7e-157]} {Smed: dd_Smed_v6_6911_0_2, dd_Smed_v6_6911_0_2, [RH, Score=486, Expect=2e-171]} {RNA1509_59209, RNA1509_6725} {RNA1310_9715, RNA1509_59209} {RNA1509_59209, RNA815_4428} |
6. | MligTC455_42673 | 862 | 17.96 | Mlig455_017086 | Neo: - Age: Down-Down-Up |
0.95 | - | - | 0.950 | - | - | - | Mlig455_017086 {REF} {Length: 1828} {Pfam: Baculovirus polyhedron envelope protein, PEP, C terminus [PF04513.14, score=40.6]; TATA element modulatory factor 1 DNA binding [PF12329.10, score=31.9]; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 [PF10473.11, score=31.8]; Laminin Domain II [PF06009.14, score=31.1]; Crescentin protein [PF19220.2, score=30.6]; Bacterial protein of unknown function (DUF948) [PF06103.13, score=30.4]; Formin Homology 2 Domain [PF02181.25, score=30.2]; Intra-flagellar transport protein 57 [PF10498.11, score=29.8]; Protein of unknown function (DUF1664) [PF07889.14, score=28.6]; Growth-arrest specific micro-tubule binding [PF13851.8, score=28.6]; Domain of unknown function (DUF4201) [PF13870.8, score=27.2]; Autophagy protein 16 (ATG16) [PF08614.13, score=25.7]; Septation ring formation regulator, EzrA [PF06160.14, score=25.2]; Myelin regulatory factor ICA domain [PF13887.8, score=24.9]; TPR/MLP1/MLP2-like protein [PF07926.14, score=24.8]; Biogenesis of lysosome-related organelles complex-1 subunit 2 [PF10046.11, score=24.7]; BRE1 E3 ubiquitin ligase [PF08647.13, score=24.6]; Haemolysin XhlA [PF10779.11, score=24.6]; AAA domain [PF13166.8, score=24.6]; Seryl-tRNA synthetase N-terminal domain [PF02403.24, score=23.9]; Vps51/Vps67 [PF08700.13, score=23.9]; Domain of unknown function (DUF2935) [PF11155.10, score=23.9]; Vps53-like, N-terminal [PF04100.14, score=23.3]; Protein of unknown function (DUF713) [PF05218.16, score=23.3]; BAR domain of APPL family [PF16746.7, score=23.2]; Apolipoprotein A1/A4/E domain [PF01442.20, score=22.9]; Cholesterol uptake porter CUP1 of Mce4, putative [PF11887.10, score=22.7]; Exonuclease VII, large subunit [PF02601.17, score=22.3]; Uncharacterized conserved protein [PF10241.11, score=22.2]; Initiation control protein YabA [PF06156.15, score=22.1]; Protein of unknown function (DUF3829) [PF12889.9, score=21.9]; Flagellar FliJ protein [PF02050.18, score=21.7]; Apg6 coiled-coil region [PF17675.3, score=21.7]; Golgi transport complex subunit 5 [PF10392.11, score=21.4]; Inhibitor of growth proteins N-terminal histone-binding [PF12998.9, score=21.3]; COG (conserved oligomeric Golgi) complex component, COG2 [PF06148.13, score=21.2]; Autophagy protein ATG17-like domain [PF04108.14, score=21.0]; Prefoldin subunit [PF01920.22, score=20.6]; Zinc finger-containing protein [PF10146.11, score=20.6]; Hydrophobic surface binding protein A [PF12296.10, score=20.5]; Protein of unknown function (DUF3450) [PF11932.10, score=20.4]; TATA element modulatory factor 1 TATA binding [PF12325.10, score=20.1]; Fungal N-terminal domain of STAND proteins [PF17111.7, score=19.9]; Cell division protein ZapB [PF06005.14, score=19.8]; Tape measure protein [PF20155.1, score=19.8]; Spc7 kinetochore protein [PF08317.13, score=19.4]; Afadin- and alpha -actinin-Binding [PF11559.10, score=19.4]; Fez1 [PF06818.17, score=19.3]; Uncharacterized conserved protein (DUF2203) [PF09969.11, score=19.3]; Protein of unknown function (DUF745) [PF05335.15, score=19.2]; RNA polymerase II transcription mediator complex subunit 9 [PF07544.15, score=19.2]; DASH complex subunit Dam1 [PF08653.12, score=19.2]; TMPIT-like protein [PF07851.15, score=19.0]; Spindle and kinetochore-associated protein 1 [PF07160.14, score=18.8]; Calcium binding and coiled-coil domain (CALCOCO1) like [PF07888.13, score=18.2]; Prominin [PF05478.13, score=17.8]; Myosin tail [PF01576.21, score=17.4]} {Mouse: ENSMUSG00000043183, Simc1, SUMO-interacting motifs containing 1, [Score=74.7, Expect=4e-16]} {RNA1509_46691} {RNA1310_4498.2, RNA1509_46691} {RNA1509_46691, RNA815_1649} |