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Results for MligTC455_46821

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_46821 774 16.12 Mlig455_001266, Mlig455_001267

Neo: -

Age: logFC(26M/2M)=-0.676

Mlig455_001266 {REF} {Length: 1556} {RNA1509_53831} {RNA1310_22633.1} {RNA815_35538.1}

Mlig455_001267 {REF} {Length: 1534} {RNA1509_53831} {RNA1310_21024.1} {RNA815_35538.1}

Cumulative graph for MligTC455_46821

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.063 4.21 0.95077 1.00000
RegionR2 -0.763 4.21 0.23929 0.61366
RegionR3 -1.199 4.21 0.04709 0.38001
RegionR4 1.512 4.21 0.03780 0.15964
RegionR5 -0.337 4.21 0.56928 0.92818
RegionR6 -1.063 4.21 0.08436 0.53557
RegionR7 0.903 4.21 0.13618 0.69268
RegionR8 1.01 4.21 0.21139 0.81530

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.389 4.21 0.83741 1.00000
RegenerationR2 0.367 4.21 0.55845 0.89779
RegenerationR3 0.747 4.21 0.27335 0.70775
RegenerationR4 -0.269 4.21 0.69502 0.95185
RegenerationR5 0.318 4.21 0.62282 0.91988
RegenerationR6 0.27 4.21 0.70266 0.92593
RegenerationBL 0.031 4.21 0.96789 1.00000
RegenerationTP -0.449 4.21 0.50795 0.90542


Genes with expression patterns similar to MligTC455_46821

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_46821 774 16.12 Mlig455_001266, Mlig455_001267

Neo: -

Age: logFC(26M/2M)=-0.676

 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_001266 {REF} {Length: 1556} {RNA1509_53831} {RNA1310_22633.1} {RNA815_35538.1}

Mlig455_001267 {REF} {Length: 1534} {RNA1509_53831} {RNA1310_21024.1} {RNA815_35538.1}
2. MligTC455_40290 58 1.21 Mlig455_058728

Neo: -

Age: -

Region-enriched R2: 4.464/0.00807
Region-enriched R7: 3.833/0.03206

 3.331 0.818 0.951 - 0.735 0.827 - Mlig455_058728 {REF} {Length: 1351} {Pfam: CUB domain [PF00431.22, score=48.4]} {RNA1310_48745} {RNA815_23305}
3. MligTC455_47875 72 1.5 Mlig455_067941

Neo: -

Age: -

 3.288 0.732 0.970 - 0.831 0.755 - Mlig455_067941 {REF} {Length: 1399} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.8, Expect=7e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
4. MligTC455_47874 67 1.4 Mlig455_000340

Neo: -

Age: -

 3.241 0.732 0.970 - 0.784 0.755 - Mlig455_000340 {REF} {Length: 1412} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.4, Expect=9e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
5. MligTC455_44176 89 1.85 Mlig455_022911

Neo: -

Age: -

 TNKS 2.656 - 0.959 - 0.879 0.818 - Mlig455_022911 {REF} {Length: 1883} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=67.0]; Ankyrin repeats (3 copies) [PF12796.9, score=64.6]; Ankyrin repeats (many copies) [PF13857.8, score=59.2]; Ankyrin repeat [PF13606.8, score=50.9]; Ankyrin repeat [PF00023.32, score=50.1]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=57.8, Expect=3e-08]; ENSG00000285372, AC270292.3, tankyrase, [Score=56.6, Expect=7e-08]; ENSG00000236759, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000238134, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000204371, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000206376, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000227333, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000232045, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000224143, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000029534, ANK1, ankyrin 1, [Score=55.5, Expect=2e-07]} {Mouse: ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=57.8, Expect=1e-08]; ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=57.8, Expect=1e-08]; ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=57.8, Expect=2e-08]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=57.4, Expect=1e-08]; ENSMUSG00000013787, Ehmt2, euchromatic histone lysine N-methyltransferase 2, [Score=55.8, Expect=9e-08]; ENSMUSG00000063932, Poteg, POTE ankyrin domain family, member G, [Score=55.5, Expect=8e-08]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=55.5, Expect=1e-07]; ENSMUSG00000110591, Gm31371, predicted gene, 31371, [Score=55.5, Expect=4e-08]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=55.1, Expect=8e-08]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=55.1, Expect=8e-08]} {Dmel: FBgn0040752, Prosap, [Score=58.9, Expect=6e-09]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=53.5, Expect=2e-07]} {Smed: dd_Smed_v6_2072_0_22, dd_Smed_v6_2072_0_22, [Score=62.0, Expect=4e-10]} {RNA1509_39040} {RNA1310_19494} {RNA815_14632}
6. MligTC455_46444 201 4.19 Mlig455_001021

Neo: -

Age: -

 2.655 - 0.981 - 0.814 0.860 - Mlig455_001021 {REF} {Length: 629} {RNA1509_14730} {RNA1310_23260} {RNA815_18139}
7. MligTC455_41368 369 7.68 Mlig455_007683, Mlig455_020872, Mlig455_020918, Mlig455_020998

Neo: -

Age: -

 2.637 - 0.972 - 0.841 0.824 -

Mlig455_007683 {REF} {Length: 1379} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020872 {REF} {Length: 1217} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020918 {REF} {Length: 1220} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020998 {REF} {Length: 1235} {RNA1310_25040.1} {RNA815_12562.1}
8. MligTC455_28693 60 1.26 Mlig455_022354

Neo: -

Age: -

 2.62 - 0.968 - 0.805 0.847 - Mlig455_022354 {REF} {Length: 816} {Pfam: WSC domain [PF01822.21, score=53.0]; PAN domain [PF00024.28, score=20.6]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=48.1, Expect=2e-06]} {RNA1509_43359} {RNA1310_59466.1} {RNA815_19988}
9. MligTC455_31933 105 2.18 Mlig455_062083

Neo: -

Age: -

 ANGPTL1 2.603 - 0.950 - 0.828 0.825 - Mlig455_062083 {REF} {Length: 1024} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=156.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=135, Expect=7e-36]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=132, Expect=2e-34]; ENSG00000101280, ANGPT4, angiopoietin 4, [Score=132, Expect=9e-35]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=137, Expect=1e-36]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=132, Expect=4e-35]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=131, Expect=1e-34]} {Dmel: FBgn0034160, CG5550, [Score=130, Expect=2e-36]} {Celegans: WBGene00020516, T15B7.1, [Score=73.9, Expect=9e-15]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=126, Expect=2e-32]} {RNA1509_14033} {RNA1310_32107.2} {RNA815_17173.3}
10. MligTC455_44307 53 1.1 Mlig455_006144

Neo: -

Age: -

Region-enriched R2: 7.453/0.02887

 2.599 - 0.986 - 0.820 0.793 - Mlig455_006144 {REF} {Length: 1270} {Pfam: F5/8 type C domain [PF00754.27, score=27.0]} {Smed: dd_Smed_v6_46759_0_1, dd_Smed_v6_46759_0_1, [RH, Score=47.0, Expect=1e-06]} {RNA1509_2129} {RNA1310_49415} {RNA815_42540}
11. MligTC455_34115 6573 136.93 Mlig455_017846, Mlig455_047865

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.581

Region-enriched R2: 4.896/0.00130

 2.592 - 0.965 - 0.823 0.804 -

Mlig455_017846 {REF} {Length: 1260} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1310_63880, RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701, RNA815_12890.1}

Mlig455_047865 {REF} {Length: 1135} {RNA1509_4845} {RNA1310_63880} {RNA815_12890.1}
12. MligTC455_41226 44 0.92 Mlig455_019357, Mlig455_059122

Neo: -

Age: -

 GALNT1 2.588 - 0.972 - 0.782 0.834 -

Mlig455_019357 {REF} {Length: 1606} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=97.5]; Glycosyltransferase like family 2 [PF13641.8, score=38.9]; N-terminal domain of galactosyltransferase [PF02709.16, score=29.1]; Glycosyltransferase like family 2 [PF10111.11, score=18.5]} {Human: ENSG00000141429, GALNT1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=318, Expect=2e-103]; ENSG00000139629, GALNT6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=311, Expect=4e-100]; ENSG00000257594, GALNT4, polypeptide N-acetylgalactosaminyltransferase 4, [Score=305, Expect=3e-98]; ENSG00000259075, POC1B-GALNT4, POC1B-GALNT4 readthrough, [Score=305, Expect=3e-98]} {Mouse: ENSMUSG00000000420, Galnt1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=316, Expect=1e-102]; ENSMUSG00000037280, Galnt6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=308, Expect=9e-99]; ENSMUSG00000060988, Galnt13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=302, Expect=3e-97]} {Dmel: FBgn0050463, CG30463, [Score=345, Expect=5e-113]} {Celegans: WBGene00001630, gly-5, Polypeptide N-acetylgalactosaminyltransferase 5, [Score=350, Expect=3e-115]} {Smed: dd_Smed_v6_8580_0_1, dd_Smed_v6_8580_0_1, [Score=353, Expect=1e-117]} {RNA1310_25598} {RNA815_36943}

Mlig455_059122 {REF} {Length: 2150} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=96.4]; Glycosyltransferase like family 2 [PF13641.8, score=35.9]; N-terminal domain of galactosyltransferase [PF02709.16, score=29.5]} {Human: ENSG00000141429, GALNT1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=313, Expect=2e-101]; ENSG00000139629, GALNT6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=307, Expect=2e-98]; ENSG00000257594, GALNT4, polypeptide N-acetylgalactosaminyltransferase 4, [Score=300, Expect=6e-96]; ENSG00000259075, POC1B-GALNT4, POC1B-GALNT4 readthrough, [Score=299, Expect=7e-96]; ENSG00000144278, GALNT13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=298, Expect=1e-95]} {Mouse: ENSMUSG00000000420, Galnt1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=311, Expect=1e-100]; ENSMUSG00000037280, Galnt6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=305, Expect=1e-97]; ENSMUSG00000060988, Galnt13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=298, Expect=8e-96]; ENSMUSG00000026994, Galnt3, polypeptide N-acetylgalactosaminyltransferase 3, [Score=296, Expect=5e-94]; ENSMUSG00000026828, Galnt5, polypeptide N-acetylgalactosaminyltransferase 5, [Score=296, Expect=2e-91]} {Dmel: FBgn0050463, CG30463, [Score=340, Expect=3e-111]} {Celegans: WBGene00001630, gly-5, Polypeptide N-acetylgalactosaminyltransferase 5, [Score=344, Expect=3e-113]} {Smed: dd_Smed_v6_8580_0_1, dd_Smed_v6_8580_0_1, [Score=350, Expect=3e-116]} {RNA1310_25598} {RNA815_36943}
13. MligTC455_16370 2203 45.9 Mlig455_030628, Mlig455_031013

Neo: -

Age: logFC(26M/2M)=-0.323

 ARMC3 2.564 - - 0.718 0.956 0.890 -

Mlig455_030628 {REF} {Length: 2931} {TRANSSPLICED} {Pfam: Ethylene-responsive protein kinase Le-CTR1 [PF14381.8, score=96.4]; Armadillo/beta-catenin-like repeat [PF00514.25, score=81.7]; HEAT repeats [PF13646.8, score=63.8]; HEAT-like repeat [PF13513.8, score=49.3]; V-ATPase subunit H [PF11698.10, score=49.2]; HEAT repeat [PF02985.24, score=38.5]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=29.0]} {Human: ENSG00000165309, ARMC3, armadillo repeat containing 3, [Score=496, Expect=2e-162]} {Mouse: ENSMUSG00000037683, Armc3, armadillo repeat containing 3, [Score=471, Expect=7e-153]} {Dmel: FBgn0033794, CG13326, [RH, Score=62.8, Expect=1e-09]} {Smed: dd_Smed_v6_9679_0_1, dd_Smed_v6_9679_0_1, [Score=665, Expect=0.0]} {RNA1509_7762} {RNA1310_5967} {RNA815_1775.1}

Mlig455_031013 {REF} {Length: 2952} {TRANSSPLICED} {Pfam: Ethylene-responsive protein kinase Le-CTR1 [PF14381.8, score=96.8]; Armadillo/beta-catenin-like repeat [PF00514.25, score=80.8]; HEAT repeats [PF13646.8, score=63.8]; V-ATPase subunit H [PF11698.10, score=50.9]; HEAT-like repeat [PF13513.8, score=48.4]; HEAT repeat [PF02985.24, score=40.7]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=31.6]; Required for nuclear transport of RNA pol II C-terminus 1 [PF10363.11, score=18.7]} {Human: ENSG00000165309, ARMC3, armadillo repeat containing 3, [Score=474, Expect=3e-154]} {Mouse: ENSMUSG00000037683, Armc3, armadillo repeat containing 3, [Score=335, Expect=1e-101]} {Dmel: FBgn0033794, CG13326, [RH, Score=62.8, Expect=1e-09]} {Smed: dd_Smed_v6_9679_0_1, dd_Smed_v6_9679_0_1, [Score=643, Expect=0.0]} {RNA1509_7762} {RNA1310_5967} {RNA815_1775.1}
14. MligTC455_44022 2840 59.17 Mlig455_027438

Neo: -

Age: Down-Down-Down

 STYXL1 2.564 - - 0.809 0.971 0.784 - Mlig455_027438 {REF} {Length: 1257} {Pfam: Dual specificity phosphatase, catalytic domain [PF00782.22, score=65.4]; Rhodanese-like domain [PF00581.22, score=29.2]} {Human: ENSG00000127952, STYXL1, serine/threonine/tyrosine interacting like 1, [RH, Score=196, Expect=9e-61]} {Mouse: ENSMUSG00000019178, Styxl1, serine/threonine/tyrosine interacting-like 1, [RH, Score=187, Expect=2e-57]} {Dmel: FBgn0039742, CG15528, [Score=52.8, Expect=6e-08]} {Celegans: WBGene00017428, F13D11.3, [Score=55.8, Expect=2e-09]} {Smed: dd_Smed_v6_11358_0_1, dd_Smed_v6_11358_0_1, [RH, Score=251, Expect=7e-83]} {RNA1509_4392} {RNA1310_10767.2} {RNA815_8325.1}
15. MligTC455_36985 363 7.57 Mlig455_046905

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.516

 SCNN1A 2.553 - 0.985 - 0.822 0.746 - Mlig455_046905 {REF} {Length: 2490} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=171.1]} {Human: ENSG00000111319, SCNN1A, sodium channel epithelial 1 alpha subunit, [Score=68.6, Expect=2e-11]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=67.0, Expect=3e-11]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=58.2, Expect=1e-08]} {Smed: dd_Smed_v6_29341_0_1, dd_Smed_v6_29341_0_1, [Score=100, Expect=2e-22]} {RNA1509_33610} {RNA1310_13314.1, RNA1509_33610} {RNA1509_33610, RNA815_4277}
16. MligTC455_17568 33 0.68 Mlig455_059349, Mlig455_065584

Neo: -

Age: -

 2.546 - 0.982 - 0.782 0.782 -

Mlig455_059349 {REF} {Length: 1132} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}

Mlig455_065584 {REF} {Length: 1132} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}
17. MligTC455_23150 3195 66.56 Mlig455_009524, Mlig455_009530

Neo: -

Age: -

Region-enriched R2: 3.504/0.00000
Region-enriched R3: 1.656/0.02560

 CDK16 2.522 - 0.966 - 0.749 0.807 -

Mlig455_009524 {REF} {Length: 3287} {Pfam: Protein kinase domain [PF00069.27, score=218.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.2]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [RH, Score=463, Expect=7e-159]; ENSG00000059758, CDK17, cyclin dependent kinase 17, [RH, Score=447, Expect=2e-151]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [RH, Score=464, Expect=2e-158]; ENSMUSG00000020015, Cdk17, cyclin-dependent kinase 17, [RH, Score=449, Expect=2e-152]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=362, Expect=2e-118]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [RH, Score=417, Expect=3e-138]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [RH, Score=449, Expect=6e-151]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}

Mlig455_009530 {REF} {Length: 3384} {Pfam: Protein kinase domain [PF00069.27, score=208.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [Score=432, Expect=5e-147]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [Score=431, Expect=4e-146]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=329, Expect=9e-107]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [Score=392, Expect=2e-130]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [Score=411, Expect=6e-137]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}
18. MligTC455_38416 576 12.01 Mlig455_055909

Neo: -

Age: logFC(26M/2M)=-0.455

 2.518 - - 0.794 0.959 0.765 - Mlig455_055909 {REF} {Length: 2549} {TRANSSPLICED} {RNA1509_23555} {RNA1310_17205.1, RNA1509_23555} {RNA1509_23555, RNA815_8113}
19. MligTC455_31901 18 0.38 Mlig455_022355

Neo: -

Age: -

 2.517 - 0.982 - 0.768 0.767 - Mlig455_022355 {REF} {Length: 541} {Pfam: PAN domain [PF00024.28, score=19.0]} {RNA1310_125793} {RNA815_23776.1}
20. MligTC455_46445 169 3.51 Mlig455_065678

Neo: -

Age: Down-Down-Up

 2.515 - 0.981 - 0.816 0.718 - Mlig455_065678 {REF} {Length: 599} {RNA1509_44880} {RNA1310_1166} {RNA815_18139}
21. MligTC455_46067 548 11.42 Mlig455_054518, Mlig455_055436, Mlig455_055448

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.305/0.04262

 GRIK3, GRIK4 2.512 - 0.984 - 0.755 0.773 -

Mlig455_054518 {REF} {Length: 4725} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=91.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.2]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=222, Expect=5e-60]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=222, Expect=6e-60]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=218, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=3e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=215, Expect=1e-57]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=9e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=213, Expect=9e-57]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=224, Expect=2e-60]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=224, Expect=9e-61]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=220, Expect=2e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=215, Expect=1e-57]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=296, Expect=6e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=312, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_14215, RNA1509_40992} {RNA1310_5620.1, RNA1509_14215, RNA1509_40992} {RNA1509_14215, RNA1509_40992, RNA815_1965}

Mlig455_055436 {REF} {Length: 4732} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=6e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=7e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=7e-59]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=9e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=211, Expect=2e-56]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=226, Expect=3e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_40992} {RNA1310_5620.1} {RNA815_1965}

Mlig455_055448 {REF} {Length: 4726} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=9e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=9e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=8e-59]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=217, Expect=2e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=7e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=6e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=225, Expect=4e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=217, Expect=9e-59]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=5e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_32892, RNA1509_40992} {RNA1310_5620.1, RNA1509_32892} {RNA1509_32892, RNA815_1965}
22. MligTC455_41540 190 3.96 Mlig455_060056

Neo: -

Age: -

Region-enriched R2: 6.605/0.00196

 GLUL 2.506 - 0.950 - 0.825 0.731 - Mlig455_060056 {REF} {Length: 1355} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=57.3]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=47.5]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=511, Expect=1e-180]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=511, Expect=0.0]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=511, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=515, Expect=0.0]} {Smed: dd_Smed_v6_896_0_1, dd_Smed_v6_896_0_1, [RH, Score=545, Expect=0.0]} {RNA1509_47000} {RNA1310_22329.2} {RNA815_4116.6}
23. MligTC455_40119 114 2.37 Mlig455_034596

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.158/0.00258

 KCNIP1 2.492 0.723 0.963 - - 0.806 - Mlig455_034596 {REF} {Length: 1987} {Pfam: EF-hand domain pair [PF13499.8, score=42.4]; EF hand [PF00036.34, score=38.6]; EF-hand domain [PF13405.8, score=33.5]; EF hand [PF13202.8, score=31.2]; EF-hand domain pair [PF13833.8, score=28.7]} {Human: ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=122, Expect=3e-32]; ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=122, Expect=2e-32]; ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=119, Expect=1e-30]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=124, Expect=5e-33]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=122, Expect=1e-32]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=100, Expect=6e-25]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=103, Expect=6e-26]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=122, Expect=7e-33]} {RNA1310_43225} {RNA815_33406}
24. MligTC455_48714 132 2.74 Mlig455_037041

Neo: -

Age: -

Region-enriched R2: 4.531/0.00493

 2.484 - 0.977 - 0.729 0.778 - Mlig455_037041 {REF} {Length: 1099} {RNA1509_35038} {RNA1310_72135} {RNA815_37404}
25. MligTC455_41608 65 1.36 Mlig455_039948

Neo: -

Age: Down-Up-Down

 2.474 0.779 0.967 - 0.728 - - Mlig455_039948 {REF} {Length: 4005} {RNA1310_25006} {RNA815_53385}
26. MligTC455_07624 777 16.19 Mlig455_062715

Neo: -

Age: Up-Down-Up

 STOM 2.466 - - - 0.953 0.787 0.726 Mlig455_062715 {REF} {Length: 3417} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=112.9]} {Human: ENSG00000148175, STOM, stomatin, [RH, Score=365, Expect=3e-126]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [RH, Score=362, Expect=2e-125]} {Dmel: FBgn0260657, CG42540, [RH, Score=384, Expect=9e-131]} {Celegans: WBGene00006064, sto-2, Stomatin-2, [RH, Score=393, Expect=2e-136]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=379, Expect=3e-132]} {RNA1509_47159, RNA1509_9137} {RNA1310_11482.1, RNA1509_47159, RNA1509_9137} {RNA1509_47159, RNA1509_9137, RNA815_6842}
27. MligTC455_38288 5006 104.28 Mlig455_045260, Mlig455_069180

Neo: -

Age: logFC(26M/2M)=0.302

Region-specific R2: 4.563

Region-enriched R2: 3.648/0.00002

 RNF217 2.454 - 0.958 - 0.726 0.770 -

Mlig455_045260 {REF} {Length: 2327} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=53.3]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=129, Expect=8e-31]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=124, Expect=1e-29]} {Dmel: FBgn0031857, LUBEL, Linear Ubiquitin E3 ligase, [Score=56.2, Expect=1e-07]} {Smed: dd_Smed_v6_7110_0_1, dd_Smed_v6_7110_0_1, [Score=114, Expect=1e-26]} {RNA1509_27317} {RNA1310_23955} {RNA815_6068}

Mlig455_069180 {REF} {Length: 2719} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=54.2]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=130, Expect=3e-31]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=125, Expect=4e-30]} {Dmel: FBgn0031857, LUBEL, Linear Ubiquitin E3 ligase, [Score=55.8, Expect=1e-07]} {Smed: dd_Smed_v6_7110_0_1, dd_Smed_v6_7110_0_1, [Score=113, Expect=3e-26]} {RNA1509_27317} {RNA1310_23955} {RNA815_6068}
28. MligTC455_17299 538 11.21 Mlig455_036559, Mlig455_057787

Neo: -

Age: -

Region-enriched R2: 5.046/0.00000
Region-enriched R3: 3.527/0.00004

 2.428 - 0.986 - 0.713 0.729 -

Mlig455_036559 {REF} {Length: 718} {RNA1509_57277} {RNA1310_52579, RNA1509_57277} {RNA1509_57277, RNA815_26706}

Mlig455_057787 {REF} {Length: 741} {RNA1509_57277} {RNA1310_52579} {RNA815_26706}
29. MligTC455_31291 845 17.6 Mlig455_013887, Mlig455_057722

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.442

Region-enriched R8: 1.865/0.01323

 GRIA2 2.422 - - - 0.968 0.734 0.720

Mlig455_013887 {REF} {Length: 2798} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=81.4]; Ligand-gated ion channel [PF00060.28, score=67.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=62.5]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=178, Expect=5e-47]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=177, Expect=1e-46]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=173, Expect=3e-45]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=178, Expect=4e-47]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=177, Expect=8e-47]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=173, Expect=2e-45]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=2e-41]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=156, Expect=4e-40]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=171, Expect=4e-45]} {RNA1509_15014} {RNA1310_5818.1} {RNA815_1723}

Mlig455_057722 {REF} {Length: 3577} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=77.9]; Ligand-gated ion channel [PF00060.28, score=65.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=61.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=177, Expect=2e-45]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=176, Expect=4e-45]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=172, Expect=9e-44]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=177, Expect=2e-45]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=175, Expect=5e-45]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=172, Expect=6e-44]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=1e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=154, Expect=2e-38]} {Smed: dd_Smed_v6_22973_0_1, dd_Smed_v6_22973_0_1, [Score=176, Expect=1e-45]} {RNA1509_15014} {RNA1310_5818.1, RNA1509_15014} {RNA1509_15014, RNA815_1723}
30. MligTC455_20442 14887 310.15 Mlig455_023972, Mlig455_066251

Neo: -

Age: Down-Up-Up

 TSPAN16 2.386 - - 0.716 0.950 0.720 -

Mlig455_023972 {REF} {Length: 2924} {Pfam: Tetraspanin family [PF00335.22, score=77.6]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=49.3, Expect=2e-06]} {Mouse: ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=48.1, Expect=4e-06]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=67.0, Expect=1e-12]} {Smed: dd_Smed_v6_3175_0_1, dd_Smed_v6_3175_0_1, [RH, Score=105, Expect=2e-26]} {RNA1509_1984} {RNA1310_20011} {RNA815_7057.1}

Mlig455_066251 {REF} {Length: 2553} {Pfam: Tetraspanin family [PF00335.22, score=77.6]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=49.3, Expect=2e-06]} {Mouse: ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=48.1, Expect=4e-06]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=67.0, Expect=1e-12]} {Smed: dd_Smed_v6_3175_0_1, dd_Smed_v6_3175_0_1, [RH, Score=105, Expect=2e-26]} {RNA1509_18769, RNA1509_1984, RNA1509_20386} {RNA1310_20011, RNA1509_18769, RNA1509_20386} {RNA1509_18769, RNA1509_20386, RNA815_7057.1}
31. MligTC455_17412 44 0.91 Mlig455_069737

Neo: -

Age: -

Region-enriched R2: 5.062/0.00923

 1.872 - 0.962 - 0.910 - - Mlig455_069737 {REF} {Length: 1628} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=42.8]} {Smed: dd_Smed_v6_31564_0_1, dd_Smed_v6_31564_0_1, [Score=72.8, Expect=3e-14]} {RNA1310_45758} {RNA815_42912}
32. MligTC455_17044 502 10.46 Mlig455_015598

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.701

 PUF60 1.852 - - - 0.957 - 0.895 Mlig455_015598 {REF} {Length: 4506} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=145.2]; RNA recognition motif [PF16367.7, score=26.9]} {Human: ENSG00000274081, PUF60, poly(U) binding splicing factor 60, [Score=308, Expect=4e-97]; ENSG00000179950, PUF60, poly(U) binding splicing factor 60, [Score=308, Expect=7e-97]} {Mouse: ENSMUSG00000002524, Puf60, poly-U binding splicing factor 60, [Score=310, Expect=2e-97]} {Dmel: FBgn0028577, hfp, half pint, [RH, Score=225, Expect=2e-64]} {Celegans: WBGene00004389, rnp-6, RNP (RRM RNA binding domain) containing, [RH, Score=229, Expect=4e-69]} {Smed: dd_Smed_v6_3853_0_3, dd_Smed_v6_3853_0_3, [Score=350, Expect=6e-114]} {RNA1509_18272, RNA1509_23731} {RNA1310_20367.1, RNA1509_23731} {RNA1509_23731, RNA815_10999}
33. MligTC455_29173 380 7.93 Mlig455_031607

Neo: -

Age: -

 ANKRD42 1.842 - - - 0.950 0.892 - Mlig455_031607 {REF} {Length: 7774} {TRANSSPLICED} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=128.5]; Ankyrin repeats (3 copies) [PF12796.9, score=121.4]; Ankyrin repeats (many copies) [PF13857.8, score=115.0]; Ankyrin repeat [PF13606.8, score=88.5]; Ankyrin repeat [PF00023.32, score=78.1]} {Human: ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [RH, Score=501, Expect=9e-174]} {Mouse: ENSMUSG00000041343, Ankrd42, ankyrin repeat domain 42, [RH, Score=497, Expect=4e-172]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=144, Expect=7e-36]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=129, Expect=3e-31]} {Smed: dd_Smed_v6_10615_0_1, dd_Smed_v6_10615_0_1, [RH, Score=623, Expect=0.0]} {RNA1509_19358} {RNA1310_610.2} {RNA815_2353.1}
34. MligTC455_30540 1159 24.14 Mlig455_048840

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.427

 1.828 - - - 0.959 0.869 - Mlig455_048840 {REF} {Length: 3299} {TRANSSPLICED} {Smed: dd_Smed_v6_6429_0_1, dd_Smed_v6_6429_0_1, [RH, Score=123, Expect=2e-30]} {RNA1509_3399} {RNA1310_7154.1} {RNA815_2838.1}
35. MligTC455_43683 520 10.83 Mlig455_029440

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.407

 1.822 - - - 0.957 0.865 - Mlig455_029440 {REF} {Length: 1842} {RNA1509_21217} {RNA1310_16933.1, RNA1509_21217} {RNA1509_21217, RNA815_7959}
36. MligTC455_45496 144 2.99 Mlig455_010048

Neo: -

Age: Up-Down-Up

Region-enriched R2: 3.720/0.00332

 CAV2 1.822 - 0.980 - 0.842 - - Mlig455_010048 {REF} {Length: 2607} {Pfam: Caveolin [PF01146.19, score=125.0]} {Human: ENSG00000105971, CAV2, caveolin 2, [Score=85.5, Expect=3e-21]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [Score=89.4, Expect=7e-23]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=79.0, Expect=2e-18]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=153, Expect=1e-48]} {RNA1509_20287} {RNA1310_50581.1, RNA1509_20287} {RNA1509_20287, RNA815_31873}
37. MligTC455_40655 452 9.42 Mlig455_059219

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.334

 CHRNA3 1.817 - - - 0.860 0.957 - Mlig455_059219 {REF} {Length: 2292} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=202.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=188.5]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=337, Expect=7e-110]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=330, Expect=2e-107]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=325, Expect=4e-105]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=338, Expect=1e-110]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=338, Expect=2e-110]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=392, Expect=7e-132]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=342, Expect=4e-112]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=493, Expect=1e-171]} {RNA1509_27513, RNA1509_30398} {RNA1310_13981, RNA1509_27513, RNA1509_30398} {RNA1509_27513, RNA1509_30398, RNA815_5602}
38. MligTC455_27938 137 2.85 Mlig455_033961

Neo: -

Age: -

 1.816 - 0.988 - 0.828 - - Mlig455_033961 {REF} {Length: 3296} {Pfam: Glycine rich protein [PF12810.9, score=20.4]} {RNA1310_28736.1} {RNA815_45605}
39. MligTC455_39858 79 1.66 Mlig455_038520

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.278

 NECAB1 1.816 - 0.975 - 0.841 - - Mlig455_038520 {REF} {Length: 1812} {Pfam: EF-hand domain [PF13405.8, score=35.3]; EF hand [PF00036.34, score=33.1]; EF-hand domain pair [PF13499.8, score=27.7]; EF-hand domain pair [PF13833.8, score=27.4]; Antibiotic biosynthesis monooxygenase [PF03992.18, score=26.7]; EF hand [PF13202.8, score=23.2]} {Human: ENSG00000123119, NECAB1, N-terminal EF-hand calcium binding protein 1, [Score=187, Expect=2e-55]} {Mouse: ENSMUSG00000040536, Necab1, N-terminal EF-hand calcium binding protein 1, [Score=181, Expect=2e-53]} {RNA1310_5770} {RNA815_27367}
40. MligTC455_42379 521 10.85 Mlig455_027421

Neo: -

Age: Down-Up-Down

 1.812 - - - 0.970 - 0.842 Mlig455_027421 {REF} {Length: 1480} {Smed: dd_Smed_v6_15589_0_1, dd_Smed_v6_15589_0_1, [Score=81.3, Expect=4e-17]} {RNA1509_13870, RNA1509_44294} {RNA1310_12385.1, RNA1509_44294} {RNA1509_44294, RNA815_4422}
41. MligTC455_52232 92 1.92 Mlig455_007894, Mlig455_008001

Neo: -

Age: logFC(26M/2M)=0.549

 1.811 - 0.982 - 0.829 - -

Mlig455_007894 {REF} {Length: 1500} {RNA1310_22136} {RNA815_18832}

Mlig455_008001 {REF} {Length: 1450} {Pfam: PAN domain [PF00024.28, score=18.9]} {RNA1310_22136} {RNA815_18832}
42. MligTC455_40751 206 4.29 Mlig455_045754

Neo: -

Age: Down-Up-Down

 1.809 - 0.985 - 0.824 - - Mlig455_045754 {REF} {Length: 1094} {Pfam: Lectin C-type domain [PF00059.23, score=30.3]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=55.1, Expect=4e-09]} {RNA1310_36556.1} {RNA815_16968}
43. MligTC455_46831 32 0.66 Mlig455_000140

Neo: -

Age: -

 1.808 - 0.978 - 0.830 - - Mlig455_000140 {REF} {Length: 1100}
44. MligTC455_43072 81 1.68 Mlig455_042521

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.590/0.02161

 1.807 - 0.982 - - 0.825 - Mlig455_042521 {REF} {Length: 1049} {RNA1509_46101} {RNA1310_32444} {RNA815_30668}
45. MligTC455_19775 36 0.74 Mlig455_060359

Neo: -

Age: -

 FCN1 1.804 - 0.982 - 0.822 - - Mlig455_060359 {REF} {Length: 1109} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.9]} {Human: ENSG00000085265, FCN1, ficolin 1, [Score=99.0, Expect=2e-23]; ENSG00000142748, FCN3, ficolin 3, [Score=99.0, Expect=1e-23]; ENSG00000160339, FCN2, ficolin 2, [Score=98.2, Expect=2e-23]} {Mouse: ENSMUSG00000026938, Fcna, ficolin A, [Score=100, Expect=3e-24]} {Dmel: FBgn0034160, CG5550, [Score=97.8, Expect=7e-24]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=90.1, Expect=4e-20]} {RNA1310_67383} {RNA815_45536}
46. MligTC455_45020 386 8.05 Mlig455_012422

Neo: -

Age: -

Region-enriched R2: 4.067/0.00066
Region-enriched R3: 2.869/0.01291

 AVP 1.803 - 0.957 - - 0.846 - Mlig455_012422 {REF} {Length: 1252} {Pfam: Neurohypophysial hormones, C-terminal Domain [PF00184.19, score=36.0]} {Human: ENSG00000101200, AVP, arginine vasopressin, [Score=50.4, Expect=4e-08]} {Mouse: ENSMUSG00000037727, Avp, arginine vasopressin, [Score=52.0, Expect=7e-09]} {RNA1509_50574} {RNA1310_26737, RNA1509_50574} {RNA1509_50574, RNA815_23813}
47. MligTC455_50704 36 0.74 Mlig455_007321, Mlig455_068329

Neo: -

Age: -

 1.799 - 0.968 - 0.831 - -

Mlig455_007321 {REF} {Length: 1784} {RNA815_63232}

Mlig455_068329 {REF} {Length: 1748} {RNA815_63232}
48. MligTC455_39890 162 3.37 Mlig455_047281, Mlig455_047331, Mlig455_069333

Neo: -

Age: -

Region-enriched R2: 6.097/0.00148

 PLSCR1 1.798 - 0.975 - 0.823 - -

Mlig455_047281 {REF} {Length: 1404} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_047331 {REF} {Length: 1395} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_069333 {REF} {Length: 1416} {Pfam: Scramblase [PF03803.17, score=248.7]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=226, Expect=1e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=228, Expect=2e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=223, Expect=1e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=224, Expect=2e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=4e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=304, Expect=2e-103]} {RNA1310_29769} {RNA815_41335}
49. MligTC455_18501 200 4.16 Mlig455_031954

Neo: -

Age: Down-Up-Up

 1.793 - - - 0.957 0.836 - Mlig455_031954 {REF} {Length: 1030} {RNA1509_49054} {RNA1310_32906} {RNA815_15169}
50. MligTC455_50287 702 14.63 Mlig455_038725, Mlig455_068419

Neo: -

Age: -

 1.789 0.830 - - 0.959 - -

Mlig455_038725 {REF} {Length: 2591} {RNA1509_31365, RNA1509_59711} {RNA1310_22555.1, RNA1509_31365, RNA1509_59711} {RNA1509_31365, RNA1509_59711, RNA815_13269}

Mlig455_068419 {REF} {Length: 2512} {RNA1509_42248, RNA1509_59711} {RNA1310_22555.1, RNA1509_42248} {RNA1509_42248, RNA815_13269}
51. MligTC455_17021 49 1.02 Mlig455_030263

Neo: -

Age: -

 1.788 - 0.980 - 0.808 - - Mlig455_030263 {REF} {Length: 566} {TRANSSPLICED} {Pfam: Galactosyltransferase [PF01762.23, score=23.7]} {Dmel: FBgn0000221, brn, brainiac, [Score=45.8, Expect=1e-06]} {RNA1310_35735} {RNA815_59866}
52. MligTC455_18451 118 2.46 Mlig455_031824, Mlig455_047676

Neo: -

Age: -

 WSCD2 1.788 - 0.975 - 0.813 - -

Mlig455_031824 {REF} {Length: 1015} {Pfam: WSC domain [PF01822.21, score=53.3]; PAN domain [PF00024.28, score=21.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=63.2, Expect=6e-11]} {RNA1509_53783} {RNA1310_58580.1} {RNA815_46263}

Mlig455_047676 {REF} {Length: 926} {Pfam: WSC domain [PF01822.21, score=57.9]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=64.3, Expect=2e-11]} {Mouse: ENSMUSG00000020811, Wscd1, WSC domain containing 1, [Score=49.3, Expect=1e-06]} {RNA1310_58580.1}
53. MligTC455_18683 419 8.74 Mlig455_069928

Neo: -

Age: -

Region-specific R2: 6.066

Region-enriched R2: 4.921/0.00217

 1.786 - 0.952 - 0.834 - - Mlig455_069928 {REF} {Length: 845} {RNA1509_25826} {RNA1310_42757} {RNA815_23874}
54. MligTC455_21580 101 2.11 Mlig455_032452

Neo: -

Age: -

 WSCD2 1.785 - 0.955 - 0.830 - - Mlig455_032452 {REF} {Length: 945} {Pfam: WSC domain [PF01822.21, score=57.3]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.0, Expect=3e-07]; ENSG00000179314, WSCD1, WSC domain containing 1, [Score=51.2, Expect=6e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=53.1, Expect=9e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=52.8, Expect=9e-08]} {RNA1310_78298} {RNA815_49767}
55. MligTC455_19708 304 6.32 Mlig455_009784

Neo: -

Age: -

Region-enriched R2: 6.355/0.00039

 1.784 - 0.982 - - 0.802 - Mlig455_009784 {REF} {Length: 826} {Pfam: Pancreatic hormone peptide [PF00159.20, score=43.3]} {RNA1509_54211} {RNA1310_54505.1, RNA1509_54211} {RNA1509_54211, RNA815_29389}
56. MligTC455_19709 221 4.6 Mlig455_010385

Neo: -

Age: -

Region-enriched R2: 4.689/0.03280

 1.78 - 0.983 - - 0.797 - Mlig455_010385 {REF} {Length: 903} {Pfam: Pancreatic hormone peptide [PF00159.20, score=43.2]} {RNA1509_54211} {RNA1310_54505.2} {RNA815_29389}
57. MligTC455_45487 110 2.3 Mlig455_004129, Mlig455_060457

Neo: -

Age: -

 1.778 - 0.982 - - 0.796 -

Mlig455_004129 {REF} {Length: 1131} {Pfam: PAN domain [PF00024.28, score=18.8]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1310_37660} {RNA815_17816.1}

Mlig455_060457 {REF} {Length: 1507} {Pfam: PAN domain [PF00024.28, score=19.5]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_54623} {RNA1310_33480} {RNA815_17816.1}
58. MligTC455_45208 929 19.35 Mlig455_070298

Neo: -

Age: logFC(26M/2M)=-0.334

 1.776 - - 0.799 0.977 - - Mlig455_070298 {REF} {Length: 1543} {RNA1509_21491, RNA1509_35528} {RNA1310_3497.1, RNA1509_21491, RNA1509_35528} {RNA1509_21491, RNA1509_35528, RNA815_14551}
59. MligTC455_15679 88 1.82 Mlig455_057219

Neo: -

Age: Down-Up-Up

 WSCD2 1.772 - 0.982 - 0.790 - - Mlig455_057219 {REF} {Length: 1035} {Pfam: WSC domain [PF01822.21, score=55.1]; PAN domain [PF00024.28, score=27.0]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.8, Expect=2e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=51.6, Expect=3e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.5, Expect=5e-08]} {RNA1509_46267} {RNA1310_46146} {RNA815_32275.1}
60. MligTC455_10899 46 0.95 Mlig455_013784, Mlig455_013915

Neo: -

Age: -

 1.77 - 0.982 - - 0.788 -

Mlig455_013784 {REF} {Length: 1362} {Pfam: Glycine rich protein [PF12810.9, score=20.8]} {RNA1509_28715} {RNA1310_91773} {RNA815_35307}

Mlig455_013915 {REF} {Length: 1516} {Pfam: Glycine rich protein [PF12810.9, score=20.3]} {RNA1509_28715} {RNA1310_91773} {RNA815_35307}
61. MligTC455_12511 68 1.42 Mlig455_017662

Neo: -

Age: -

 1.769 - 0.985 - 0.784 - - Mlig455_017662 {REF} {Length: 906} {RNA1310_37507} {RNA815_32171}
62. MligTC455_41328 417 8.68 Mlig455_057091

Neo: -

Age: Down-Up-Down

Region-enriched R2: 6.162/0.00002

 1.764 - 0.964 - - 0.800 - Mlig455_057091 {REF} {Length: 854} {RNA1310_89414} {RNA815_40489.2}
63. MligTC455_44144 1917 39.94 Mlig455_013403

Neo: -

Age: logFC(26M/2M)=-0.387

 TNKS 1.763 - - - 0.968 0.795 - Mlig455_013403 {REF} {Length: 3109} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=73.2]; Ankyrin repeats (many copies) [PF13857.8, score=57.0]; Ankyrin repeats (many copies) [PF13637.8, score=54.5]; Ion transport protein [PF00520.33, score=51.4]; Ankyrin repeat [PF00023.32, score=50.9]; Ankyrin repeat [PF13606.8, score=46.3]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=88.6, Expect=3e-17]; ENSG00000285372, AC270292.3, tankyrase, [Score=87.4, Expect=7e-17]; ENSG00000107854, TNKS2, tankyrase 2, [Score=84.3, Expect=6e-16]} {Mouse: ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=87.4, Expect=4e-17]; ENSMUSG00000024811, Tnks2, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, [Score=84.0, Expect=5e-16]} {Dmel: FBgn0004647, N, Notch, [Score=80.1, Expect=7e-15]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=82.8, Expect=6e-16]} {Smed: dd_Smed_v6_8547_0_1, dd_Smed_v6_8547_0_1, [Score=79.3, Expect=6e-15]} {RNA1509_2994} {RNA1310_1688.1, RNA1509_2994} {RNA1509_2994, RNA815_1415.1}
64. MligTC455_32644 41 0.86 Mlig455_043770, Mlig455_043786

Neo: -

Age: -

Region-enriched R2: 6.705/0.00336

 1.762 - 0.976 - 0.786 - -

Mlig455_043770 {REF} {Length: 1011} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.8, Expect=3e-11]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}

Mlig455_043786 {REF} {Length: 1348} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
65. MligTC455_44596 3708 77.26 Mlig455_017126

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.194/0.00002

 1.752 - 0.976 - 0.776 - - Mlig455_017126 {REF} {Length: 833} {RNA1509_16537, RNA1509_37651} {RNA1310_50770, RNA1509_37651} {RNA1509_37651, RNA815_21068.1}
66. MligTC455_11765 292 6.08 Mlig455_032580, Mlig455_032642

Neo: -

Age: -

Region-specific R2: 6.434

Region-enriched R2: 4.662/0.03055

 1.75 - 0.983 - - 0.767 -

Mlig455_032580 {REF} {Length: 565} {RNA1509_42630} {RNA1310_64208} {RNA815_32993}

Mlig455_032642 {REF} {Length: 663} {RNA1509_42630} {RNA1310_64208} {RNA815_32993}
67. MligTC455_15112 80 1.67 Mlig455_038148

Neo: -

Age: -

Region-enriched R2: 4.134/0.00646
Region-enriched R7: 3.497/0.03308

 1.75 - 0.963 - - 0.787 - Mlig455_038148 {REF} {Length: 836}
68. MligTC455_20149 191 3.98 Mlig455_000246, Mlig455_058518

Neo: -

Age: -

Region-enriched R2: 4.445/0.03524

 HPCAL4, NCALD 1.745 - 0.971 - 0.774 - -

Mlig455_000246 {REF} {Length: 978} {Human: ENSG00000116983, HPCAL4, hippocalcin like 4, [Score=79.0, Expect=2e-17]; ENSG00000104490, NCALD, neurocalcin delta, [Score=79.0, Expect=2e-17]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=77.8, Expect=5e-17]; ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=75.5, Expect=1e-15]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=79.0, Expect=1e-17]; ENSMUSG00000046093, Hpcal4, hippocalcin-like 4, [Score=79.0, Expect=1e-17]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=77.0, Expect=7e-17]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=75.5, Expect=8e-16]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=83.2, Expect=3e-19]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=67.8, Expect=1e-13]} {Smed: dd_Smed_v6_2568_0_1, dd_Smed_v6_2568_0_1, [Score=72.0, Expect=2e-15]} {RNA1310_101382}

Mlig455_058518 {REF} {Length: 1176} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=82.0, Expect=2e-18]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=81.3, Expect=3e-18]; ENSG00000116983, HPCAL4, hippocalcin like 4, [Score=80.1, Expect=7e-18]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=82.0, Expect=8e-19]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=80.5, Expect=4e-18]; ENSMUSG00000046093, Hpcal4, hippocalcin-like 4, [Score=80.1, Expect=5e-18]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=84.0, Expect=1e-19]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=67.0, Expect=2e-13]} {Smed: dd_Smed_v6_2568_0_1, dd_Smed_v6_2568_0_1, [Score=73.2, Expect=8e-16]} {RNA1310_101382}
69. MligTC455_50347 549 11.43 Mlig455_012382

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.390

Region-enriched R2: 6.623/0.00000

 1.745 - 0.951 - - 0.794 - Mlig455_012382 {REF} {Length: 797} {RNA1509_48155} {RNA1310_70969.2, RNA1509_48155} {RNA1509_48155, RNA815_39712}
70. MligTC455_40993 817 17.03 Mlig455_037436, Mlig455_037459

Neo: -

Age: Down-Up-Up

Region-specific R2: 3.184

Region-enriched R2: 1.942/0.00090

 GNG3, GNG7 1.744 - 0.975 - - 0.769 -

Mlig455_037436 {REF} {Length: 861} {Pfam: GGL domain [PF00631.24, score=53.3]} {Human: ENSG00000176533, GNG7, G protein subunit gamma 7, [Score=48.5, Expect=2e-08]; ENSG00000172380, GNG12, G protein subunit gamma 12, [Score=47.0, Expect=1e-07]} {Mouse: ENSMUSG00000071658, Gng3, guanine nucleotide binding protein (G protein), gamma 3, [RH, Score=45.8, Expect=2e-07]} {Dmel: FBgn0263029, CG43324, [RH, Score=61.6, Expect=7e-14]} {Celegans: WBGene00001681, gpc-1, Guanine nucleotide-binding protein subunit gamma, [RH, Score=55.1, Expect=2e-11]} {Smed: dd_Smed_v6_1237_0_1, dd_Smed_v6_1237_0_1, [RH, Score=109, Expect=5e-33]} {RNA1509_46825} {RNA1310_42481} {RNA815_22956}

Mlig455_037459 {REF} {Length: 817} {Pfam: GGL domain [PF00631.24, score=53.6]} {Human: ENSG00000162188, GNG3, G protein subunit gamma 3, [RH, Score=46.2, Expect=1e-07]} {Mouse: ENSMUSG00000071658, Gng3, guanine nucleotide binding protein (G protein), gamma 3, [RH, Score=46.2, Expect=9e-08]} {Dmel: FBgn0263029, CG43324, [RH, Score=60.8, Expect=1e-13]} {Celegans: WBGene00001681, gpc-1, Guanine nucleotide-binding protein subunit gamma, [RH, Score=55.1, Expect=1e-11]} {Smed: dd_Smed_v6_1237_0_1, dd_Smed_v6_1237_0_1, [RH, Score=107, Expect=3e-32]} {RNA1509_46825} {RNA1310_42481} {RNA815_22956}
71. MligTC455_29768 804 16.74 Mlig455_037892, Mlig455_038927

Neo: -

Age: -

 MAP3K15, MAP3K19 1.743 - - - - 0.950 0.793

Mlig455_037892 {REF} {Length: 2619} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=175.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=128.7]; Ankyrin repeats (many copies) [PF13637.8, score=54.9]; Ankyrin repeats (3 copies) [PF12796.9, score=34.6]; Fungal protein kinase [PF17667.3, score=31.2]; Ankyrin repeats (many copies) [PF13857.8, score=29.4]; Kinase-like [PF14531.8, score=22.7]; Ankyrin repeat [PF13606.8, score=19.1]} {Human: ENSG00000180815, MAP3K15, mitogen-activated protein kinase kinase kinase 15, [Score=144, Expect=5e-36]; ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=142, Expect=2e-35]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=142, Expect=2e-36]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=127, Expect=5e-31]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=117, Expect=5e-28]} {Smed: dd_Smed_v6_9984_0_1, dd_Smed_v6_9984_0_1, [Score=127, Expect=4e-33]} {RNA1509_45037} {RNA1310_24096.1} {RNA815_5323.2}

Mlig455_038927 {REF} {Length: 6244} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=234.3]; Protein kinase domain [PF00069.27, score=182.0]; Ankyrin repeats (3 copies) [PF12796.9, score=167.4]; Ankyrin repeats (many copies) [PF13857.8, score=130.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=130.8]; Ankyrin repeat [PF13606.8, score=82.5]; Ankyrin repeat [PF00023.32, score=64.1]; CRISPR-associated protein [PF12469.10, score=34.9]; Uncharacterized protein conserved in bacteria (DUF2064) [PF09837.11, score=29.8]; ABC1 atypical kinase-like domain [PF03109.18, score=21.0]; Fungal protein kinase [PF17667.3, score=20.0]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=160, Expect=2e-39]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=158, Expect=1e-40]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=133, Expect=7e-32]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=126, Expect=8e-30]} {Smed: dd_Smed_v6_2030_0_9, dd_Smed_v6_2030_0_9, [Score=133, Expect=4e-33]} {RNA1509_45037} {RNA1310_17852.1, RNA1509_45037} {RNA1509_45037, RNA815_5323.2}
72. MligTC455_26356 62 1.3 Mlig455_042551

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.548

 GRIK2 1.742 - 0.982 - - 0.760 - Mlig455_042551 {REF} {Length: 2917} {Pfam: Ligand-gated ion channel [PF00060.28, score=82.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=60.7]; Receptor family ligand binding region [PF01094.30, score=32.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=27.3]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=144, Expect=9e-35]; ENSG00000152208, GRID2, glutamate ionotropic receptor delta type subunit 2, [Score=141, Expect=7e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=143, Expect=1e-34]; ENSMUSG00000071424, Grid2, glutamate receptor, ionotropic, delta 2, [Score=142, Expect=2e-34]} {Dmel: FBgn0051201, GluRIIE, Glutamate receptor IIE, [Score=119, Expect=3e-27]} {Celegans: WBGene00001616, glr-5, GLutamate Receptor family (AMPA), [Score=123, Expect=2e-28]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=247, Expect=4e-74]} {RNA1310_21865} {RNA815_26044}
73. MligTC455_19583 95 1.97 Mlig455_010583, Mlig455_010602

Neo: -

Age: -

Region-enriched R2: 6.442/0.00383

 1.74 - 0.954 - - 0.786 -

Mlig455_010583 {REF} {Length: 2325} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=173.5]} {Smed: dd_Smed_v6_23771_0_1, dd_Smed_v6_23771_0_1, [Score=320, Expect=4e-101]} {RNA1310_36131} {RNA815_32135}

Mlig455_010602 {REF} {Length: 2432} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=182.9]} {Smed: dd_Smed_v6_15099_0_1, dd_Smed_v6_15099_0_1, [RH, Score=346, Expect=2e-110]} {RNA1310_36131} {RNA815_32135}
74. MligTC455_48656 24 0.5 Mlig455_039647

Neo: -

Age: -

 1.736 - 0.982 - - 0.754 - Mlig455_039647 {REF} {Length: 1715} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=42.7]} {RNA1310_48037} {RNA815_27969}
75. MligTC455_43390 28 0.59 Mlig455_064273

Neo: -

Age: Down-Up-Down

 PRKAR2A 1.734 - 0.964 - 0.770 - - Mlig455_064273 {REF} {Length: 2394} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=122.5]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=40.5]} {Human: ENSG00000114302, PRKAR2A, protein kinase cAMP-dependent type II regulatory subunit alpha, [Score=305, Expect=2e-100]; ENSG00000005249, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, [Score=296, Expect=8e-97]; ENSG00000284096, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, [Score=296, Expect=8e-97]} {Mouse: ENSMUSG00000032601, Prkar2a, protein kinase, cAMP dependent regulatory, type II alpha, [Score=314, Expect=6e-104]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [Score=335, Expect=1e-112]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=219, Expect=2e-68]} {Smed: dd_Smed_v6_4188_0_1, dd_Smed_v6_4188_0_1, [Score=335, Expect=5e-113]} {RNA1509_34470} {RNA1310_27777} {RNA815_5628}
76. MligTC455_44483 88 1.84 Mlig455_027611, Mlig455_047700

Neo: -

Age: -

 WSCD2 1.731 0.749 0.982 - - - -

Mlig455_027611 {REF} {Length: 946} {Pfam: WSC domain [PF01822.21, score=54.5]; PAN domain [PF00024.28, score=23.7]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=56.2, Expect=6e-09]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=58.5, Expect=7e-10]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=52.0, Expect=9e-08]} {RNA1509_29094} {RNA1310_36326} {RNA815_27950.1}

Mlig455_047700 {REF} {Length: 949} {Pfam: WSC domain [PF01822.21, score=54.2]; PAN domain [PF00024.28, score=23.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=55.1, Expect=3e-08]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=57.4, Expect=2e-09]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=58.9, Expect=7e-10]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=52.0, Expect=1e-07]} {RNA1509_29094} {RNA1310_36326} {RNA815_27950.1}
77. MligTC455_39988 83 1.73 Mlig455_062081

Neo: -

Age: -

 1.73 - 0.962 - 0.768 - - Mlig455_062081 {REF} {Length: 447} {NoTransDecoderORF} {RNA1509_50426} {RNA1310_88257} {RNA815_17173.4}
78. MligTC455_50455 972 20.25 Mlig455_070346

Neo: -

Age: -

Region-specific R2: 4.855

Region-enriched R2: 5.186/0.00000

 1.729 - 0.960 - - 0.769 - Mlig455_070346 {REF} {Length: 932} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=34.4]; Nematode insulin-related peptide beta type [PF03488.16, score=21.4]} {RNA1509_18514, RNA1509_58074} {RNA1310_51990, RNA1509_18514, RNA1509_58074} {RNA1509_18514, RNA1509_58074, RNA815_25071}
79. MligTC455_18945 41 0.86 Mlig455_031602

Neo: -

Age: -

 1.728 - 0.952 - - 0.776 - Mlig455_031602 {REF} {Length: 914} {RNA1310_75361} {RNA815_24378}
80. MligTC455_20015 52 1.09 Mlig455_026589

Neo: -

Age: -

 1.721 - 0.965 - 0.756 - - Mlig455_026589 {REF} {Length: 611} {RNA1310_66647} {RNA815_33955}
81. MligTC455_20961 1780 37.08 Mlig455_031266

Neo: -

Age: logFC(26M/2M)=-0.283

Region-enriched R2: 1.483/0.00269

 WDR63 1.718 - - - 0.759 0.959 - Mlig455_031266 {REF} {Length: 3089} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=24.4]} {Human: ENSG00000162643, WDR63, WD repeat domain 63, [RH, Score=594, Expect=0.0]} {Mouse: ENSMUSG00000043020, Wdr63, WD repeat domain 63, [RH, Score=573, Expect=0.0]} {Dmel: FBgn0035799, CG14838, [RH, Score=176, Expect=1e-44]} {Smed: dd_Smed_v6_9187_0_1, dd_Smed_v6_9187_0_1, [RH, Score=736, Expect=0.0]} {RNA1509_2565} {RNA1310_5160, RNA1509_2565} {RNA1509_2565, RNA815_1888}
82. MligTC455_18249 2857 59.52 Mlig455_031596

Neo: -

Age: logFC(26M/2M)=-0.397

 1.711 - - - 0.969 0.742 - Mlig455_031596 {REF} {Length: 2515} {Smed: dd_Smed_v6_8351_0_1, dd_Smed_v6_8351_0_1, [RH, Score=57.4, Expect=1e-09]} {RNA1509_2999} {RNA1310_22585.1, RNA1509_2999} {RNA1509_2999, RNA815_9102}
83. MligTC455_33061 25 0.51 Mlig455_012288

Neo: -

Age: -

 SCNN1A 1.709 0.753 0.956 - - - - Mlig455_012288 {REF} {Length: 3701} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=308.1]; PT repeat [PF04886.14, score=21.2]} {Human: ENSG00000111319, SCNN1A, sodium channel epithelial 1 alpha subunit, [Score=168, Expect=1e-43]} {Mouse: ENSMUSG00000030340, Scnn1a, sodium channel, nonvoltage-gated 1 alpha, [RH, Score=174, Expect=1e-45]} {Dmel: FBgn0052792, ppk8, pickpocket 8, [Score=49.3, Expect=1e-05]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=140, Expect=1e-34]} {Smed: dd_Smed_v6_17021_0_1, dd_Smed_v6_17021_0_1, [Score=144, Expect=1e-36]} {RNA1509_31312} {RNA1310_47317} {RNA815_32296}
84. MligTC455_50594 440 9.18 Mlig455_010362

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.701

Region-enriched R2: 4.104/0.00000

 1.708 - 0.961 - - 0.747 - Mlig455_010362 {REF} {Length: 685} {RNA1509_30018} {RNA1310_56512.2} {RNA815_28562}
85. MligTC455_18682 1190 24.79 Mlig455_037756

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.877

Region-enriched R2: 4.609/0.00000

 1.704 - 0.955 - - 0.749 - Mlig455_037756 {REF} {Length: 1188} {RNA1509_25826} {RNA1310_42757} {RNA815_23874}
86. MligTC455_43690 262 5.46 Mlig455_035029, Mlig455_053437

Neo: -

Age: -

Region-enriched R2: 6.108/0.00708

 WSCD2 1.703 - 0.967 - 0.736 - -

Mlig455_035029 {REF} {Length: 893} {Pfam: WSC domain [PF01822.21, score=50.2]; PAN domain [PF00024.28, score=29.7]} {RNA1310_42429} {RNA815_24291.1}

Mlig455_053437 {REF} {Length: 972} {Pfam: WSC domain [PF01822.21, score=52.4]; PAN domain [PF00024.28, score=29.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=44.7, Expect=1e-05]} {RNA1310_42429} {RNA815_24291.1}
87. MligTC455_43715 48 0.99 Mlig455_034191

Neo: -

Age: Down-Up-Down

Region-enriched R2: 7.969/0.00817

 1.701 - 0.970 - - 0.731 - Mlig455_034191 {REF} {Length: 895} {Pfam: WSC domain [PF01822.21, score=39.9]; PAN domain [PF14295.8, score=21.0]; PAN domain [PF00024.28, score=19.9]} {RNA1310_46313} {RNA815_23250}
88. MligTC455_12512 80 1.68 Mlig455_017689

Neo: -

Age: -

 1.699 - 0.982 - 0.717 - - Mlig455_017689 {REF} {Length: 934} {RNA1310_37507} {RNA815_32171}
89. MligTC455_44187 34 0.71 Mlig455_052509

Neo: -

Age: -

 1.698 - 0.976 - 0.722 - - Mlig455_052509 {REF} {Length: 883} {Pfam: Lectin C-type domain [PF00059.23, score=31.5]} {RNA1509_20946} {RNA1310_41618} {RNA815_32434}
90. MligTC455_44380 28 0.58 Mlig455_000679, Mlig455_000682, Mlig455_000734

Neo: -

Age: -

 1.695 - 0.984 - - 0.711 -

Mlig455_000679 {REF} {Length: 966} {Pfam: PAN domain [PF00024.28, score=22.4]} {RNA1310_44307} {RNA815_33128}

Mlig455_000682 {REF} {Length: 1005} {Pfam: WSC domain [PF01822.21, score=41.4]; PAN domain [PF00024.28, score=21.7]} {RNA1310_44307} {RNA815_33128}

Mlig455_000734 {REF} {Length: 1006} {Pfam: WSC domain [PF01822.21, score=41.4]; PAN domain [PF00024.28, score=21.7]} {RNA1310_44307} {RNA815_33128}
91. MligTC455_10966 15 0.31 Mlig455_013154

Neo: -

Age: -

 1.69 - 0.972 - 0.718 - - Mlig455_013154 {REF} {Length: 827} {Pfam: Lectin C-type domain [PF00059.23, score=21.8]} {RNA1509_20946} {RNA1310_65161} {RNA815_4785.1}
92. MligTC455_20009 4606 95.96 Mlig455_038152, Mlig455_038257

Neo: -

Age: -

Region-enriched R4: 1.035/0.02931

 1.689 - - - 0.965 0.724 -

Mlig455_038152 {REF} {Length: 1064} {Smed: dd_Smed_v6_8141_0_1, dd_Smed_v6_8141_0_1, [RH, Score=94.7, Expect=3e-26]} {RNA1509_10830, RNA1509_16892} {RNA1310_37711, RNA1509_10830} {RNA1509_10830, RNA815_18837}

Mlig455_038257 {REF} {Length: 2711} {Smed: dd_Smed_v6_8141_0_1, dd_Smed_v6_8141_0_1, [RH, Score=94.7, Expect=3e-26]} {RNA1509_16892, RNA1509_40689} {RNA1310_37711, RNA1509_16892, RNA1509_40689} {RNA1509_16892, RNA1509_40689, RNA815_18837}
93. MligTC455_15663 35 0.73 Mlig455_062572

Neo: -

Age: logFC(26M/2M)=1.011

 1.688 - 0.978 - 0.710 - - Mlig455_062572 {REF} {Length: 1735} {Pfam: PAN domain [PF00024.28, score=21.9]} {RNA1310_35902.2} {RNA815_33023}
94. MligTC455_44184 101 2.11 Mlig455_012174

Neo: Irradiation

Age: -

 MGAT1 1.688 - 0.982 - 0.706 - - Mlig455_012174 {REF} {Length: 1520} {Pfam: GNT-I family [PF03071.17, score=64.8]; Lectin C-type domain [PF00059.23, score=39.5]} {Human: ENSG00000131446, MGAT1, mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, [Score=59.7, Expect=4e-09]} {Mouse: ENSMUSG00000020346, Mgat1, mannoside acetylglucosaminyltransferase 1, [Score=66.2, Expect=2e-11]} {Dmel: FBgn0034521, Mgat1, Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1, [Score=69.7, Expect=1e-12]} {Celegans: WBGene00001637, gly-12, GLYcosylation related; UDP-N-acetylglucosamine:a-3-D-mannoside b-1,2-N-acetylglucosaminyltransferase I, [Score=65.1, Expect=3e-11]} {Smed: dd_Smed_v6_12622_0_1, dd_Smed_v6_12622_0_1, [Score=64.3, Expect=4e-11]} {RNA1509_44523} {RNA1310_41618} {RNA815_32434}
95. MligTC455_22763 1893 39.44 Mlig455_026105

Neo: -

Age: logFC(26M/2M)=-0.375

Region-enriched R2: 1.072/0.04204

 ELOVL4 1.683 - - 0.711 0.972 - - Mlig455_026105 {REF} {Length: 3163} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=218.7]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [RH, Score=322, Expect=4e-110]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [RH, Score=318, Expect=2e-108]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [RH, Score=218, Expect=6e-70]} {Celegans: WBGene00001245, elo-7, Elongation of very long chain fatty acids protein, [Score=80.5, Expect=3e-17]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [RH, Score=358, Expect=3e-125]} {RNA1509_16116, RNA1509_31650, RNA1509_5216} {RNA1310_6579.2, RNA1509_16116, RNA1509_31650, RNA1509_5216} {RNA1509_16116, RNA1509_31650, RNA1509_5216, RNA815_7910}
96. MligTC455_47420 218 4.54 Mlig455_017159, Mlig455_048110

Neo: -

Age: -

Region-specific R2: 6.469

Region-enriched R2: 5.851/0.00135

 1.683 - 0.956 - - 0.727 -

Mlig455_017159 {REF} {Length: 1062} {RNA1509_35349} {RNA1310_81586}

Mlig455_048110 {REF} {Length: 527} {RNA1310_81586}
97. MligTC455_09697 52 1.08 Mlig455_009478, Mlig455_061921

Neo: -

Age: -

 CD207 1.681 - 0.958 - 0.723 - -

Mlig455_009478 {REF} {Length: 1068} {Pfam: Lectin C-type domain [PF00059.23, score=39.5]} {Human: ENSG00000116031, CD207, CD207 molecule, [Score=48.5, Expect=5e-06]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=1e-13]} {RNA1310_33496.1} {RNA815_23317}

Mlig455_061921 {REF} {Length: 776} {Pfam: Lectin C-type domain [PF00059.23, score=35.3]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=69.7, Expect=4e-14]} {RNA1310_33496.1} {RNA815_23317}
98. MligTC455_46823 69 1.44 Mlig455_040455, Mlig455_042847

Neo: -

Age: -

Region-enriched R2: 5.281/0.02950

 ANGPTL2 1.678 - 0.963 - - 0.715 -

Mlig455_040455 {REF} {Length: 1444} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=152.3]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=129, Expect=8e-34]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=129, Expect=9e-34]; ENSG00000085265, FCN1, ficolin 1, [Score=128, Expect=1e-34]; ENSG00000160339, FCN2, ficolin 2, [Score=125, Expect=1e-33]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=132, Expect=4e-35]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=129, Expect=6e-34]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=127, Expect=3e-33]} {Dmel: FBgn0033312, CG8642, [Score=117, Expect=4e-30]} {Celegans: WBGene00017013, ensh-1, [Score=55.1, Expect=2e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=111, Expect=2e-27]} {RNA1509_26827} {RNA1310_31596.2} {RNA815_17173.3}

Mlig455_042847 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=154.0]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=132, Expect=7e-35]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=132, Expect=1e-34]; ENSG00000085265, FCN1, ficolin 1, [Score=130, Expect=2e-35]; ENSG00000130812, ANGPTL6, angiopoietin like 6, [Score=126, Expect=1e-32]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=136, Expect=2e-36]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=132, Expect=5e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=130, Expect=1e-34]} {Dmel: FBgn0033312, CG8642, [Score=117, Expect=4e-30]} {Celegans: WBGene00017013, ensh-1, [Score=57.4, Expect=3e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=114, Expect=2e-28]} {RNA1509_26827} {RNA1310_31596.2} {RNA815_17173.3}
99. MligTC455_12451 63 1.31 Mlig455_008444

Neo: -

Age: -

Region-enriched R8: 4.645/0.00722
Region-enriched R7: 3.937/0.01020

 1.677 0.726 0.951 - - - - Mlig455_008444 {REF} {Length: 791}
100. MligTC455_19360 1380 28.75 Mlig455_065641

Neo: -

Age: logFC(26M/2M)=-0.869

 1.676 - - - 0.972 0.704 - Mlig455_065641 {REF} {Length: 843} {RNA1509_52437} {RNA1310_43315.2} {RNA815_22018.1}

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