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Results for MligTC455_47057

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_47057 309 6.45 Mlig455_011433

Neo: -

Age: Down-Up-Down

DPCD Mlig455_011433 {REF} {Length: 944} {Pfam: DPCD protein family [PF14913.8, score=212.8]} {Human: ENSG00000166171, DPCD, deleted in primary ciliary dyskinesia homolog (mouse), [RH, Score=179, Expect=6e-57]} {Mouse: ENSMUSG00000041035, Gm17018, predicted gene 17018, [RH, Score=175, Expect=2e-55]} {Dmel: FBgn0035164, CG13901, [RH, Score=113, Expect=4e-31]} {RNA1509_36541} {RNA1310_37624, RNA1509_36541} {RNA1509_36541, RNA815_20457.1}

Cumulative graph for MligTC455_47057

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -6.009 2.822 0.13173 0.73123
RegionR2 0.882 2.822 0.35160 0.74513
RegionR3 1.397 2.822 0.04758 0.38200
RegionR4 0.677 2.822 0.46980 0.79777
RegionR5 0.029 2.822 0.84173 1.00000
RegionR6 -0.133 2.822 0.89370 1.00000
RegionR7 1.428 2.822 0.12410 0.66368
RegionR8 1.73 2.822 0.08940 0.56611

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 7.239 2.822 0.05206 0.70489
RegenerationR2 0.488 2.822 0.28236 0.72593
RegenerationR3 0.005 2.822 0.99490 1.00000
RegenerationR4 0.304 2.822 0.58684 0.90754
RegenerationR5 0.346 2.822 0.53564 0.87716
RegenerationR6 1.528 2.822 0.01462 0.14889
RegenerationBL 0.23 2.822 0.73148 1.00000
RegenerationTP -0.243 2.822 0.72796 1.00000


Genes with expression patterns similar to MligTC455_47057

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_47057 309 6.45 Mlig455_011433

Neo: -

Age: Down-Up-Down

DPCD 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_011433 {REF} {Length: 944} {Pfam: DPCD protein family [PF14913.8, score=212.8]} {Human: ENSG00000166171, DPCD, deleted in primary ciliary dyskinesia homolog (mouse), [RH, Score=179, Expect=6e-57]} {Mouse: ENSMUSG00000041035, Gm17018, predicted gene 17018, [RH, Score=175, Expect=2e-55]} {Dmel: FBgn0035164, CG13901, [RH, Score=113, Expect=4e-31]} {RNA1509_36541} {RNA1310_37624, RNA1509_36541} {RNA1509_36541, RNA815_20457.1}
2. MligTC455_15569 487 10.15 Mlig455_067138, Mlig455_068636

Neo: -

Age: -

Region-enriched R2: 2.466/0.01939

1.888 - - 0.959 0.929 - -

Mlig455_067138 {REF} {Length: 332} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_27678} {RNA1310_35433} {RNA815_11024.1}

Mlig455_068636 {REF} {Length: 720} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_27678} {RNA1310_34530, RNA1509_27678} {RNA1509_27678, RNA815_11024.1}
3. MligTC455_07421 19136 398.66 Mlig455_029662

Neo: -

Age: Down-Up-Up

Region-specific R8: 3.646

Region-enriched R8: 3.196/0.00000
Region-enriched R7: 1.280/0.00593

SLC25A24 1.781 0.831 - 0.950 - - - Mlig455_029662 {REF} {Length: 528} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=52.9]; EF hand [PF13202.8, score=51.2]; EF-hand domain pair [PF13499.8, score=51.0]; EF-hand domain [PF13405.8, score=41.8]; EF-hand domain pair [PF13833.8, score=41.6]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=26.1]; Family of unknown function (DUF5766) [PF19070.2, score=19.0]} {Human: ENSG00000085491, SLC25A24, solute carrier family 25 member 24, [Score=48.9, Expect=5e-08]; ENSG00000284468, SLC25A24, solute carrier family 25 member 24, [Score=48.9, Expect=5e-08]; ENSG00000114854, TNNC1, troponin C1, slow skeletal and cardiac type, [Score=48.1, Expect=6e-08]} {Mouse: ENSMUSG00000091898, Tnnc1, troponin C, cardiac/slow skeletal, [Score=48.5, Expect=3e-08]; ENSMUSG00000057738, Sptan1, spectrin alpha, non-erythrocytic 1, [Score=46.2, Expect=4e-07]} {Dmel: FBgn0250789, alpha-Spec, alpha Spectrin, [Score=47.0, Expect=1e-07]} {Smed: dd_Smed_v6_11874_0_1, dd_Smed_v6_11874_0_1, [Score=45.4, Expect=3e-07]} {RNA1509_10992, RNA1509_2519, RNA1509_679} {RNA1310_66965, RNA1509_10992, RNA1509_2519, RNA1509_679} {RNA1509_10992, RNA1509_2519, RNA1509_679, RNA815_31569.1}
4. MligTC455_20339 248 5.16 Mlig455_049193

Neo: -

Age: logFC(26M/2M)=0.976

Region-enriched R8: 3.824/0.00004

1.755 0.800 - 0.955 - - - Mlig455_049193 {REF} {Length: 1276} {TRANSSPLICED} {RNA1509_32364} {RNA1310_8246} {RNA815_10070.1}
5. MligTC455_19505 530 11.03 Mlig455_065098

Neo: -

Age: -

ULK2 1.749 - - - 0.968 0.781 - Mlig455_065098 {REF} {Length: 4075} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=215.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=156.5]; Domain of unknown function (DUF3543) [PF12063.10, score=40.8]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=28.3]; RIO1 family [PF01163.24, score=21.2]; Kinase-like [PF14531.8, score=17.9]} {Human: ENSG00000083290, ULK2, unc-51 like autophagy activating kinase 2, [RH, Score=344, Expect=5e-104]; ENSG00000177169, ULK1, unc-51 like autophagy activating kinase 1, [RH, Score=333, Expect=1e-99]} {Mouse: ENSMUSG00000004798, Ulk2, unc-51 like kinase 2, [RH, Score=340, Expect=1e-102]; ENSMUSG00000029512, Ulk1, unc-51 like kinase 1, [RH, Score=331, Expect=4e-99]} {Dmel: FBgn0260945, Atg1, Autophagy-related 1, [RH, Score=360, Expect=8e-112]} {Celegans: WBGene00006786, unc-51, Serine/threonine-protein kinase unc-51, [RH, Score=351, Expect=1e-108]} {Smed: dd_Smed_v6_10237_0_1, dd_Smed_v6_10237_0_1, [RH, Score=276, Expect=2e-86]} {RNA1509_51818, RNA1509_9723} {RNA1310_2515, RNA1509_51818} {RNA1509_51818, RNA815_10960.1}
6. MligTC455_17958 490 10.21 Mlig455_068231

Neo: -

Age: logFC(26M/2M)=-0.406

CCDC83 1.726 - - - 0.956 - 0.770 Mlig455_068231 {REF} {Length: 2825} {Pfam: Domain of unknown function (DUF4618) [PF15397.8, score=19.3]} {Human: ENSG00000150676, CCDC83, coiled-coil domain containing 83, [RH, Score=145, Expect=2e-38]} {Mouse: ENSMUSG00000030617, Ccdc83, coiled-coil domain containing 83, [RH, Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_16528_0_1, dd_Smed_v6_16528_0_1, [RH, Score=96.7, Expect=7e-22]} {RNA1509_34307, RNA1509_49481} {RNA1310_7992.1, RNA1509_34307, RNA1509_49481} {RNA1509_34307, RNA1509_49481, RNA815_3361.1}
7. MligTC455_27833 787 16.39 Mlig455_038040

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.399

1.699 - - - 0.955 - 0.744 Mlig455_038040 {REF} {Length: 25047} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=128.0]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=113.8]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=77.8]; Integrase zinc binding domain [PF17921.3, score=71.9]; Integrase core domain [PF00665.28, score=47.3]; Aspartyl protease [PF13650.8, score=39.6]; gag-polyprotein putative aspartyl protease [PF13975.8, score=35.9]; Retroviral aspartyl protease [PF00077.22, score=27.3]; Aspartyl protease [PF09668.12, score=24.2]; Putative peptidase (DUF1758) [PF05585.14, score=21.9]; DDE superfamily endonuclease [PF13358.8, score=19.0]} {Smed: dd_Smed_v6_1574_6_40, dd_Smed_v6_1574_6_40, [Score=336, Expect=2e-100]} {RNA1509_12237, RNA1509_41842} {RNA1310_131.1, RNA1509_41842} {RNA1509_41842, RNA815_52.1}
8. MligTC455_27427 1504 31.33 Mlig455_008363

Neo: -

Age: -

Region-enriched R2: 1.925/0.00033

MMADHC 1.693 - - - 0.951 0.742 - Mlig455_008363 {REF} {Length: 2540} {TRANSSPLICED} {Pfam: Methylmalonic aciduria and homocystinuria type D protein [PF10229.11, score=194.2]} {Human: ENSG00000168288, MMADHC, methylmalonic aciduria and homocystinuria, cblD type, [RH, Score=155, Expect=2e-45]} {Mouse: ENSMUSG00000026766, Mmadhc, methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria, [RH, Score=144, Expect=2e-41]} {Dmel: FBgn0030101, CG12118, [RH, Score=65.9, Expect=2e-12]} {Celegans: WBGene00013577, Y76A2B.5, [RH, Score=152, Expect=6e-45]} {Smed: dd_Smed_v6_2046_0_1, dd_Smed_v6_2046_0_1, [RH, Score=149, Expect=6e-44]} {RNA1509_11927, RNA1509_17948, RNA1509_29105, RNA1509_38364, RNA1509_7644} {RNA1310_28926.2, RNA1509_11927, RNA1509_17948, RNA1509_29105, RNA1509_38364, RNA1509_7644} {RNA1509_11927, RNA1509_17948, RNA1509_29105, RNA1509_38364, RNA1509_7644, RNA815_5644.1}
9. MligTC455_42148 1810 37.71 Mlig455_061808, Mlig455_061848

Neo: Irradiation

Age: logFC(26M/2M)=-0.453

UGCG 1.664 - - - 0.960 - 0.704

Mlig455_061808 {REF} {Length: 2757} {Pfam: Glycosyl transferase family 21 [PF13506.8, score=138.2]; Glycosyltransferase like family 2 [PF13641.8, score=56.9]; Glycosyl transferase family group 2 [PF13632.8, score=22.5]} {Human: ENSG00000148154, UGCG, UDP-glucose ceramide glucosyltransferase, [Score=296, Expect=6e-97]} {Mouse: ENSMUSG00000028381, Ugcg, UDP-glucose ceramide glucosyltransferase, [Score=291, Expect=3e-95]} {Dmel: FBgn0067102, GlcT-1, Ceramide glucosyltransferase, [RH, Score=333, Expect=7e-111]} {Celegans: WBGene00019127, cgt-3, Ceramide glucosyltransferase 3, [RH, Score=288, Expect=4e-93]} {Smed: dd_Smed_v6_2757_0_1, dd_Smed_v6_2757_0_1, [RH, Score=298, Expect=2e-97]} {RNA1509_7879} {RNA1310_8913} {RNA815_2874}

Mlig455_061848 {REF} {Length: 2911} {Pfam: Glycosyl transferase family 21 [PF13506.8, score=138.2]; Glycosyltransferase like family 2 [PF13641.8, score=56.9]; Glycosyl transferase family group 2 [PF13632.8, score=22.5]} {Human: ENSG00000148154, UGCG, UDP-glucose ceramide glucosyltransferase, [Score=295, Expect=2e-96]} {Mouse: ENSMUSG00000028381, Ugcg, UDP-glucose ceramide glucosyltransferase, [Score=290, Expect=1e-94]} {Dmel: FBgn0067102, GlcT-1, Ceramide glucosyltransferase, [RH, Score=333, Expect=7e-111]} {Celegans: WBGene00019127, cgt-3, Ceramide glucosyltransferase 3, [RH, Score=287, Expect=9e-93]} {Smed: dd_Smed_v6_2757_0_1, dd_Smed_v6_2757_0_1, [RH, Score=298, Expect=3e-97]} {RNA1509_3776, RNA1509_55381} {RNA1310_8913, RNA1509_3776, RNA1509_55381} {RNA1509_3776, RNA1509_55381, RNA815_2874}
10. MligTC455_34706 1472 30.67 Mlig455_059159, Mlig455_065531

Neo: -

Age: -

AGO2 0.984 - - - 0.984 - -

Mlig455_059159 {REF} {Length: 7005} {Pfam: Piwi domain [PF02171.19, score=363.8]; Mid domain of argonaute [PF16487.7, score=113.6]; N-terminal domain of argonaute [PF16486.7, score=92.1]; PAZ domain [PF02170.24, score=81.0]; Argonaute linker 1 domain [PF08699.12, score=78.2]; Argonaute linker 2 domain [PF16488.7, score=52.0]} {Human: ENSG00000123908, AGO2, argonaute 2, RISC catalytic component, [RH, Score=1248, Expect=0.0]; ENSG00000092847, AGO1, argonaute 1, RISC catalytic component, [RH, Score=1230, Expect=0.0]; ENSG00000126070, AGO3, argonaute 3, RISC catalytic component, [RH, Score=1220, Expect=0.0]; ENSG00000134698, AGO4, argonaute 4, RISC catalytic component, [RH, Score=1201, Expect=0.0]} {Mouse: ENSMUSG00000036698, Ago2, argonaute RISC catalytic subunit 2, [RH, Score=1251, Expect=0.0]; ENSMUSG00000041530, Ago1, argonaute RISC catalytic subunit 1, [RH, Score=1230, Expect=0.0]; ENSMUSG00000028842, Ago3, argonaute RISC catalytic subunit 3, [RH, Score=1218, Expect=0.0]; ENSMUSG00000042500, Ago4, argonaute RISC catalytic subunit 4, [RH, Score=1200, Expect=0.0]} {Dmel: FBgn0262739, AGO1, Argonaute-1, [RH, Score=1323, Expect=0.0]} {Celegans: WBGene00000105, alg-1, Argonaute-like, [RH, Score=1245, Expect=0.0]} {Smed: dd_Smed_v6_3861_0_1, dd_Smed_v6_3861_0_1, [RH, Score=1427, Expect=0.0]} {RNA1509_19989, RNA1509_34423, RNA1509_53824} {RNA1310_7009, RNA1509_19989, RNA1509_34423, RNA1509_53824} {RNA1509_19989, RNA1509_34423, RNA1509_53824, RNA815_1509.1}

Mlig455_065531 {REF} {Length: 7345} {Pfam: Piwi domain [PF02171.19, score=364.9]; Mid domain of argonaute [PF16487.7, score=113.6]; N-terminal domain of argonaute [PF16486.7, score=92.2]; PAZ domain [PF02170.24, score=81.0]; Argonaute linker 1 domain [PF08699.12, score=78.2]; Argonaute linker 2 domain [PF16488.7, score=51.9]} {Human: ENSG00000123908, AGO2, argonaute 2, RISC catalytic component, [RH, Score=1249, Expect=0.0]; ENSG00000092847, AGO1, argonaute 1, RISC catalytic component, [RH, Score=1230, Expect=0.0]; ENSG00000126070, AGO3, argonaute 3, RISC catalytic component, [RH, Score=1221, Expect=0.0]; ENSG00000134698, AGO4, argonaute 4, RISC catalytic component, [RH, Score=1203, Expect=0.0]} {Mouse: ENSMUSG00000036698, Ago2, argonaute RISC catalytic subunit 2, [RH, Score=1252, Expect=0.0]; ENSMUSG00000041530, Ago1, argonaute RISC catalytic subunit 1, [RH, Score=1230, Expect=0.0]; ENSMUSG00000028842, Ago3, argonaute RISC catalytic subunit 3, [RH, Score=1219, Expect=0.0]; ENSMUSG00000042500, Ago4, argonaute RISC catalytic subunit 4, [RH, Score=1201, Expect=0.0]} {Dmel: FBgn0262739, AGO1, Argonaute-1, [RH, Score=1323, Expect=0.0]} {Celegans: WBGene00000105, alg-1, Argonaute-like, [RH, Score=1245, Expect=0.0]} {Smed: dd_Smed_v6_3861_0_1, dd_Smed_v6_3861_0_1, [RH, Score=1427, Expect=0.0]} {RNA1509_15818, RNA1509_28180, RNA1509_34423} {RNA1310_7009, RNA1509_15818, RNA1509_28180} {RNA1509_15818, RNA1509_28180, RNA815_1509.1}
11. MligTC455_29497 364 7.58 Mlig455_040257

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.261

CARMIL1 0.978 - - 0.978 - - - Mlig455_040257 {REF} {Length: 4691} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=26.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=21.7]} {Human: ENSG00000079691, CARMIL1, capping protein regulator and myosin 1 linker 1, [Score=217, Expect=1e-56]; ENSG00000159753, CARMIL2, capping protein regulator and myosin 1 linker 2, [Score=214, Expect=8e-56]} {Mouse: ENSMUSG00000021338, Carmil1, capping protein regulator and myosin 1 linker 1, [Score=220, Expect=9e-58]; ENSMUSG00000050357, Carmil2, capping protein regulator and myosin 1 linker 2, [Score=219, Expect=2e-57]} {Dmel: FBgn0033212, LRR, Leucine-rich repeat, [Score=224, Expect=2e-59]} {Celegans: WBGene00010641, crml-1, CARMIL (Capping, ARp2/3, Myosin I Linker protein) homolog, [Score=137, Expect=1e-32]} {Smed: dd_Smed_v6_4832_0_1, dd_Smed_v6_4832_0_1, [RH, Score=119, Expect=5e-27]} {RNA1509_39723, RNA1509_49256, RNA1509_52275} {RNA1310_2561.1, RNA1509_39723, RNA1509_49256, RNA1509_52275} {RNA1509_39723, RNA1509_49256, RNA1509_52275, RNA815_7147}
12. MligTC455_43396 2260 47.08 Mlig455_039856, Mlig455_039890

Neo: -

Age: Up-Down-Down

USP9X 0.977 - - - 0.977 - -

Mlig455_039856 {REF} {Length: 10853} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=176.8]; Domain of unknown function (DUF3517) [PF12030.10, score=137.8]; Ubiquitin carboxyl-terminal hydrolase [PF13423.8, score=78.1]} {Human: ENSG00000124486, USP9X, ubiquitin specific peptidase 9 X-linked, [RH, Score=2207, Expect=0.0]; ENSG00000114374, USP9Y, ubiquitin specific peptidase 9 Y-linked, [RH, Score=2165, Expect=0.0]} {Mouse: ENSMUSG00000031010, Usp9x, ubiquitin specific peptidase 9, X chromosome, [RH, Score=2196, Expect=0.0]; ENSMUSG00000069044, Usp9y, ubiquitin specific peptidase 9, Y chromosome, [RH, Score=2092, Expect=0.0]} {Dmel: FBgn0005632, faf, fat facets, [RH, Score=1732, Expect=0.0]} {Celegans: WBGene00011980, T24B8.7, Ubiquitin carboxyl-terminal hydrolase, [RH, Score=215, Expect=3e-55]} {Smed: dd_Smed_v6_2963_0_1, dd_Smed_v6_2963_0_1, [RH, Score=1189, Expect=0.0]} {RNA1509_1645} {RNA1310_409} {RNA815_1673}

Mlig455_039890 {REF} {Length: 9937} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=176.8]; Domain of unknown function (DUF3517) [PF12030.10, score=137.7]; Ubiquitin carboxyl-terminal hydrolase [PF13423.8, score=78.1]} {Human: ENSG00000124486, USP9X, ubiquitin specific peptidase 9 X-linked, [RH, Score=2193, Expect=0.0]; ENSG00000114374, USP9Y, ubiquitin specific peptidase 9 Y-linked, [RH, Score=2153, Expect=0.0]} {Mouse: ENSMUSG00000031010, Usp9x, ubiquitin specific peptidase 9, X chromosome, [RH, Score=2185, Expect=0.0]; ENSMUSG00000069044, Usp9y, ubiquitin specific peptidase 9, Y chromosome, [RH, Score=2077, Expect=0.0]} {Dmel: FBgn0005632, faf, fat facets, [Score=1731, Expect=0.0]} {Celegans: WBGene00011980, T24B8.7, Ubiquitin carboxyl-terminal hydrolase, [RH, Score=215, Expect=3e-55]} {Smed: dd_Smed_v6_2963_0_1, dd_Smed_v6_2963_0_1, [Score=1182, Expect=0.0]} {RNA1509_12984, RNA1509_1645, RNA1509_43665} {RNA1310_409, RNA1509_12984, RNA1509_43665} {RNA1509_12984, RNA1509_43665, RNA815_1673}
13. MligTC455_13280 164 3.42 Mlig455_042501

Neo: -

Age: Down-Up-Down

0.973 - - - 0.973 - - Mlig455_042501 {REF} {Length: 3811} {Pfam: Caspase domain [PF00656.24, score=30.2]} {RNA1509_43988} {RNA1310_8586} {RNA815_7730.1}
14. MligTC455_52968 1829 38.11 Mlig455_051189

Neo: -

Age: logFC(26M/2M)=-0.300

PRKACB 0.972 - - - 0.972 - - Mlig455_051189 {REF} {Length: 2703} {Pfam: Protein kinase domain [PF00069.27, score=221.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=112.7]; Kinase-like [PF14531.8, score=23.1]} {Human: ENSG00000142875, PRKACB, protein kinase cAMP-activated catalytic subunit beta, [RH, Score=430, Expect=1e-152]} {Mouse: ENSMUSG00000005469, Prkaca, protein kinase, cAMP dependent, catalytic, alpha, [Score=441, Expect=7e-156]; ENSMUSG00000005034, Prkacb, protein kinase, cAMP dependent, catalytic, beta, [Score=431, Expect=5e-151]} {Dmel: FBgn0000273, Pka-C1, Protein kinase, cAMP-dependent, catalytic subunit 1, [Score=445, Expect=2e-157]} {Celegans: WBGene00002189, kin-1, cAMP-dependent protein kinase catalytic subunit, [Score=448, Expect=7e-159]} {Smed: dd_Smed_v6_13597_0_1, dd_Smed_v6_13597_0_1, [Score=456, Expect=4e-162]} {RNA1509_24103} {RNA1310_24783} {RNA815_8477}
15. MligTC455_32844 2230 46.47 Mlig455_026516

Neo: -

Age: -

USP7 0.967 - - - 0.967 - - Mlig455_026516 {REF} {Length: 5842} {TRANSSPLICED} {Pfam: Ubiquitin-specific protease C-terminal [PF14533.8, score=195.1]; Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=167.6]; ICP0-binding domain of Ubiquitin-specific protease 7 [PF12436.10, score=133.9]; MATH domain [PF00917.28, score=54.1]; Ubiquitin carboxyl-terminal hydrolase [PF13423.8, score=33.6]} {Human: ENSG00000187555, USP7, ubiquitin specific peptidase 7, [RH, Score=993, Expect=0.0]} {Mouse: ENSMUSG00000022710, Usp7, ubiquitin specific peptidase 7, [RH, Score=993, Expect=0.0]} {Dmel: FBgn0030366, Usp7, Ubiquitin-specific protease 7, [RH, Score=863, Expect=0.0]} {Celegans: WBGene00010406, math-33, Ubiquitin carboxyl-terminal hydrolase 7, [RH, Score=458, Expect=7e-143]} {Smed: dd_Smed_v6_7459_0_1, dd_Smed_v6_7459_0_1, [RH, Score=939, Expect=0.0]} {RNA1509_1139, RNA1509_14459, RNA1509_21575} {RNA1310_1449, RNA1509_14459, RNA1509_21575} {RNA1509_14459, RNA1509_21575, RNA815_487.1}
16. MligTC455_42814 106 2.21 Mlig455_021632

Neo: -

Age: -

Region-enriched R7: 2.352/0.02725

0.967 - - 0.967 - - - Mlig455_021632 {REF} {Length: 1748} {RNA1310_28094}
17. MligTC455_12797 59 1.23 Mlig455_049659

Neo: -

Age: -

PCDHA5 0.966 - - - - 0.966 - Mlig455_049659 {REF} {Length: 4667} {Pfam: Cadherin domain [PF00028.19, score=196.7]; Cadherin-like [PF16184.7, score=28.8]; Cadherin-like [PF08266.14, score=24.3]} {Human: ENSG00000204965, PCDHA5, protocadherin alpha 5, [Score=174, Expect=5e-44]; ENSG00000253846, PCDHGA10, protocadherin gamma subfamily A, 10, [Score=169, Expect=3e-42]; ENSG00000165194, PCDH19, protocadherin 19, [Score=166, Expect=4e-41]} {Mouse: ENSMUSG00000055421, Pcdh9, protocadherin 9, [Score=176, Expect=2e-44]; ENSMUSG00000102697, Pcdhac2, protocadherin alpha subfamily C, 2, [Score=169, Expect=3e-42]} {Dmel: FBgn0284247, ds, dachsous, [Score=182, Expect=5e-46]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=154, Expect=2e-37]} {Smed: dd_Smed_v6_12697_0_1, dd_Smed_v6_12697_0_1, [Score=219, Expect=7e-59]} {RNA1509_41935} {RNA1310_16730.1} {RNA815_7760}
18. MligTC455_34793 1077 22.43 Mlig455_013259

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.384

PRKAG1 0.966 - - - 0.966 - - Mlig455_013259 {REF} {Length: 5569} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=204.5]; CBS domain [PF00571.30, score=104.3]} {Human: ENSG00000181929, PRKAG1, protein kinase AMP-activated non-catalytic subunit gamma 1, [RH, Score=384, Expect=3e-124]; ENSG00000106617, PRKAG2, protein kinase AMP-activated non-catalytic subunit gamma 2, [RH, Score=365, Expect=9e-117]} {Mouse: ENSMUSG00000067713, Prkag1, protein kinase, AMP-activated, gamma 1 non-catalytic subunit, [RH, Score=382, Expect=1e-123]; ENSMUSG00000028944, Prkag2, protein kinase, AMP-activated, gamma 2 non-catalytic subunit, [RH, Score=365, Expect=4e-117]} {Dmel: FBgn0264357, SNF4Agamma, SNF4/AMP-activated protein kinase gamma subunit, [RH, Score=389, Expect=6e-115]} {Celegans: WBGene00013732, aakg-1, AMP-Activated protein Kinase Gamma subunit, [RH, Score=334, Expect=7e-100]} {Smed: dd_Smed_v6_4877_0_1, dd_Smed_v6_4877_0_1, [RH, Score=305, Expect=2e-94]} {RNA1509_9777} {RNA1310_4569} {RNA815_2038.1}
19. MligTC455_43274 2146 44.71 Mlig455_021861, Mlig455_021937

Neo: -

Age: -

0.966 - - - 0.966 - -

Mlig455_021861 {REF} {Length: 3255} {TRANSSPLICED} {Pfam: PAS fold [PF08447.14, score=26.4]; PAS domain [PF14598.8, score=25.5]} {RNA1509_28562, RNA1509_32390} {RNA1310_24520.1, RNA1509_28562} {RNA1509_28562, RNA815_15256}

Mlig455_021937 {REF} {Length: 3201} {Pfam: PAS domain [PF14598.8, score=25.9]} {RNA1509_32390} {RNA1310_24520.1, RNA1509_32390} {RNA1509_32390, RNA815_15256}
20. MligTC455_25480 454 9.45 Mlig455_002934

Neo: -

Age: -

ITK 0.964 - - - 0.964 - - Mlig455_002934 {REF} {Length: 6820} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=267.9]; Protein kinase domain [PF00069.27, score=133.8]; SH2 domain [PF00017.26, score=77.3]; PH domain [PF00169.31, score=32.0]; Variant SH3 domain [PF14604.8, score=28.5]; SH3 domain [PF00018.30, score=27.5]; BTK motif [PF00779.21, score=24.1]; SH3 domain [PF17902.3, score=18.6]} {Human: ENSG00000113263, ITK, IL2 inducible T cell kinase, [Score=432, Expect=5e-143]; ENSG00000010671, BTK, Bruton tyrosine kinase, [Score=427, Expect=2e-140]; ENSG00000135605, TEC, tec protein tyrosine kinase, [Score=416, Expect=2e-136]} {Mouse: ENSMUSG00000020395, Itk, IL2 inducible T cell kinase, [RH, Score=420, Expect=3e-138]} {Dmel: FBgn0003502, Btk29A, Btk family kinase at 29A, [RH, Score=451, Expect=2e-148]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=294, Expect=7e-92]} {Smed: dd_Smed_v6_4818_0_1, dd_Smed_v6_4818_0_1, [RH, Score=641, Expect=0.0]} {RNA1509_14892} {RNA1310_2046, RNA1509_14892} {RNA1509_14892, RNA815_350}
21. MligTC455_33974 520 10.84 Mlig455_026777

Neo: -

Age: -

CTNND2 0.964 - - - 0.964 - - Mlig455_026777 {REF} {Length: 5315} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=61.0]; HEAT repeats [PF13646.8, score=21.5]} {Human: ENSG00000169862, CTNND2, catenin delta 2, [Score=297, Expect=8e-85]; ENSG00000144283, PKP4, plakophilin 4, [Score=286, Expect=1e-80]} {Mouse: ENSMUSG00000022240, Ctnnd2, catenin (cadherin associated protein), delta 2, [Score=295, Expect=4e-84]; ENSMUSG00000026991, Pkp4, plakophilin 4, [Score=286, Expect=8e-83]} {Dmel: FBgn0260799, p120ctn, Adherens junction protein p120, [Score=328, Expect=5e-99]} {Celegans: WBGene00002175, jac-1, Juxtamembrane domain-associated catenin, [Score=248, Expect=1e-68]} {Smed: dd_Smed_v6_6256_0_1, dd_Smed_v6_6256_0_1, [Score=239, Expect=1e-66]} {RNA1509_6533} {RNA1310_5357} {RNA815_401.1}
22. MligTC455_15646 129 2.68 Mlig455_029052

Neo: -

Age: -

Region-enriched R4: 3.809/0.00771

0.963 - - - - 0.963 - Mlig455_029052 {REF} {Length: 1067} {RNA1310_32832} {RNA815_22228}
23. MligTC455_28422 4149 86.45 Mlig455_034947

Neo: -

Age: -

NRCAM 0.961 - - - 0.961 - - Mlig455_034947 {REF} {Length: 4799} {TRANSSPLICED} {Pfam: Immunoglobulin domain [PF13927.8, score=211.5]; Immunoglobulin I-set domain [PF07679.18, score=207.0]; Immunoglobulin domain [PF13895.8, score=160.6]; Immunoglobulin domain [PF00047.27, score=138.3]; Fibronectin type III domain [PF00041.23, score=100.2]; Immunoglobulin V-set domain [PF07686.19, score=78.2]; Immunoglobulin domain [PF18452.3, score=25.6]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=25.5]} {Human: ENSG00000091129, NRCAM, neuronal cell adhesion molecule, [RH, Score=353, Expect=9e-101]; ENSG00000163531, NFASC, neurofascin, [RH, Score=350, Expect=7e-101]} {Mouse: ENSMUSG00000026442, Nfasc, neurofascin, [RH, Score=353, Expect=9e-102]; ENSMUSG00000020598, Nrcam, neuronal cell adhesion molecule, [RH, Score=345, Expect=9e-99]} {Dmel: FBgn0264975, Nrg, Neuroglian, [RH, Score=510, Expect=2e-157]} {Celegans: WBGene00004732, sax-7, SAX-7 LONGFORM; Sensory AXon guidance, [RH, Score=328, Expect=1e-92]} {Smed: dd_Smed_v6_1916_0_1, dd_Smed_v6_1916_0_1, [RH, Score=777, Expect=0.0]} {RNA1509_629} {RNA1310_1408, RNA1509_629} {RNA1509_629, RNA815_388}
24. MligTC455_35812 912 18.99 Mlig455_063433, Mlig455_063463

Neo: -

Age: -

Region-enriched R6: 2.260/0.00346

ARHGAP45 0.961 - - - - 0.961 -

Mlig455_063433 {REF} {Length: 5901} {Pfam: RhoGAP domain [PF00620.29, score=137.5]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=27.8]} {Human: ENSG00000180448, ARHGAP45, Rho GTPase activating protein 45, [Score=104, Expect=5e-22]; ENSG00000089639, GMIP, GEM interacting protein, [Score=102, Expect=4e-21]} {Mouse: ENSMUSG00000035697, Arhgap45, Rho GTPase activating protein 45, [Score=106, Expect=9e-23]; ENSMUSG00000036246, Gmip, Gem-interacting protein, [Score=105, Expect=2e-22]} {Dmel: FBgn0030685, Graf, GTPase regulator associated with FAK, [Score=92.8, Expect=1e-18]} {Celegans: WBGene00015418, pac-1, GTPase-activating protein pac-1, [Score=91.7, Expect=1e-18]} {Smed: dd_Smed_v6_5208_0_2, dd_Smed_v6_5208_0_2, [RH, Score=143, Expect=8e-35]} {RNA1509_10752, RNA1509_23661, RNA1509_48362} {RNA1310_5626, RNA1509_10752, RNA1509_23661, RNA1509_48362} {RNA1509_10752, RNA1509_23661, RNA1509_48362, RNA815_3834}

Mlig455_063463 {REF} {Length: 4819} {Pfam: RhoGAP domain [PF00620.29, score=135.2]} {Human: ENSG00000180448, ARHGAP45, Rho GTPase activating protein 45, [Score=107, Expect=5e-23]} {Mouse: ENSMUSG00000035697, Arhgap45, Rho GTPase activating protein 45, [Score=106, Expect=6e-23]; ENSMUSG00000036246, Gmip, Gem-interacting protein, [Score=101, Expect=2e-21]} {Dmel: FBgn0030685, Graf, GTPase regulator associated with FAK, [Score=89.7, Expect=7e-18]} {Celegans: WBGene00015418, pac-1, GTPase-activating protein pac-1, [Score=89.0, Expect=8e-18]} {Smed: dd_Smed_v6_5208_0_2, dd_Smed_v6_5208_0_2, [RH, Score=142, Expect=1e-34]} {RNA1509_48362} {RNA1310_5626} {RNA815_3834}
25. MligTC455_19577 522 10.88 Mlig455_052861

Neo: -

Age: -

ZNF845 0.96 - - - 0.960 - - Mlig455_052861 {REF} {Length: 3297} {TRANSSPLICED} {Pfam: Zinc-finger double domain [PF13465.8, score=84.3]; Zinc finger, C2H2 type [PF00096.28, score=64.5]; C2H2-type zinc finger [PF13894.8, score=55.2]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=23.7]; Zinc finger C2H2-type, 3 repeats [PF18868.3, score=23.3]; zinc-finger C2H2-type [PF16622.7, score=21.7]} {Human: ENSG00000213799, ZNF845, zinc finger protein 845, [Score=170, Expect=2e-42]; ENSG00000159917, ZNF235, zinc finger protein 235, [Score=170, Expect=5e-43]; ENSG00000106261, ZKSCAN1, zinc finger with KRAB and SCAN domains 1, [Score=169, Expect=7e-44]; ENSG00000167380, ZNF226, zinc finger protein 226, [Score=169, Expect=1e-42]; ENSG00000198131, ZNF544, zinc finger protein 544, [Score=169, Expect=5e-43]; ENSG00000159915, ZNF233, zinc finger protein 233, [Score=168, Expect=8e-43]; ENSG00000281894, ZKSCAN7, zinc finger with KRAB and SCAN domains 7, [Score=167, Expect=4e-42]; ENSG00000196345, ZKSCAN7, zinc finger with KRAB and SCAN domains 7, [Score=167, Expect=4e-42]; ENSG00000144026, ZNF514, zinc finger protein 514, [Score=167, Expect=3e-44]; ENSG00000167766, ZNF83, zinc finger protein 83, [Score=167, Expect=2e-43]; ENSG00000062370, ZNF112, zinc finger protein 112, [Score=166, Expect=2e-41]; ENSG00000198464, ZNF480, zinc finger protein 480, [Score=166, Expect=9e-43]; ENSG00000184635, ZNF93, zinc finger protein 93, [Score=166, Expect=2e-42]; ENSG00000176371, ZSCAN2, zinc finger and SCAN domain containing 2, [Score=166, Expect=2e-42]; ENSG00000167384, ZNF180, zinc finger protein 180, [Score=164, Expect=2e-41]; ENSG00000121903, ZSCAN20, zinc finger and SCAN domain containing 20, [Score=164, Expect=1e-40]; ENSG00000141040, ZNF287, zinc finger protein 287, [Score=164, Expect=4e-41]; ENSG00000276219, ZNF676, zinc finger protein 676, [Score=164, Expect=7e-42]; ENSG00000170949, ZNF160, zinc finger protein 160, [Score=163, Expect=1e-40]; ENSG00000249459, ZNF286B, zinc finger protein 286B, [Score=163, Expect=7e-42]; ENSG00000186017, ZNF566, zinc finger protein 566, [Score=163, Expect=7e-43]; ENSG00000197497, ZNF665, zinc finger protein 665, [Score=163, Expect=5e-41]; ENSG00000136866, ZFP37, ZFP37 zinc finger protein, [Score=162, Expect=6e-41]; ENSG00000182318, ZSCAN22, zinc finger and SCAN domain containing 22, [Score=162, Expect=4e-42]; ENSG00000198315, ZKSCAN8, zinc finger with KRAB and SCAN domains 8, [Score=162, Expect=2e-41]; ENSG00000198346, ZNF813, zinc finger protein 813, [Score=162, Expect=3e-41]; ENSG00000184939, ZFP90, ZFP90 zinc finger protein, [Score=162, Expect=6e-41]; ENSG00000198816, ZNF358, zinc finger protein 358, [Score=162, Expect=3e-41]; ENSG00000269067, ZNF728, zinc finger protein 728, [Score=162, Expect=6e-41]} {Mouse: ENSMUSG00000060630, Zfp735, zinc finger protein 735, [Score=181, Expect=5e-47]; ENSMUSG00000078868, Gm14412, predicted gene 14412, [Score=176, Expect=2e-46]; ENSMUSG00000094429, Gm19965, predicted gene, 19965, [Score=174, Expect=1e-44]; ENSMUSG00000092416, Zfp141, zinc finger protein 141, [Score=173, Expect=1e-44]} {Dmel: FBgn0032979, Clamp, Chromatin-linked adaptor for MSL proteins, [Score=151, Expect=4e-38]} {Celegans: WBGene00012639, fezf-1, FEZ Family zinc finger protein, [Score=123, Expect=2e-31]} {Smed: dd_Smed_v6_75162_0_1, dd_Smed_v6_75162_0_1, [Score=121, Expect=2e-31]} {RNA1509_38192, RNA1509_55873} {RNA1310_31280, RNA1509_55873} {RNA1509_55873, RNA815_10368}
26. MligTC455_44709 1473 30.68 Mlig455_044126

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.323

Region-enriched R2: 1.087/0.01396

CFAP20 0.96 - - - 0.960 - - Mlig455_044126 {REF} {Length: 1458} {Pfam: Protein of unknown function (DUF667) [PF05018.15, score=306.8]} {Human: ENSG00000070761, CFAP20, cilia and flagella associated protein 20, [RH, Score=360, Expect=1e-128]} {Mouse: ENSMUSG00000031796, Cfap20, cilia and flagella associated protein 20, [RH, Score=363, Expect=9e-130]} {Dmel: FBgn0032248, Bug22, Basal body up regulated gene 22, [RH, Score=355, Expect=1e-126]} {Celegans: WBGene00008288, C54C6.6, Cilia- and flagella-associated protein 20, [RH, Score=333, Expect=4e-118]} {Smed: dd_Smed_v6_4843_0_1, dd_Smed_v6_4843_0_1, [RH, Score=363, Expect=2e-130]} {RNA1509_27107, RNA1509_35008, RNA1509_5810} {RNA1310_18346.2, RNA1509_27107, RNA1509_35008} {RNA1509_27107, RNA1509_35008, RNA815_7118.1}
27. MligTC455_16161 93 1.93 Mlig455_049990

Neo: -

Age: -

0.958 - - - - 0.958 - Mlig455_049990 {REF} {Length: 1306} {NoTransDecoderORF} {RNA1509_57552} {RNA1310_4917.1} {RNA815_25501}
28. MligTC455_23744 477 9.94 Mlig455_034500

Neo: -

Age: -

CD63 0.958 - - - - - 0.958 Mlig455_034500 {REF} {Length: 1900} {Pfam: Tetraspanin family [PF00335.22, score=86.9]} {Human: ENSG00000135404, CD63, CD63 molecule, [Score=50.4, Expect=7e-07]} {Mouse: ENSMUSG00000027215, Cd82, CD82 antigen, [Score=52.4, Expect=5e-08]} {Dmel: FBgn0032943, Tsp39D, Tetraspanin 39D, [Score=49.7, Expect=7e-07]} {Celegans: WBGene00006637, tsp-11, Tetraspanin, [Score=48.9, Expect=1e-06]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [Score=56.2, Expect=3e-09]} {RNA1509_14979} {RNA1310_633} {RNA815_1859}
29. MligTC455_41814 525 10.93 Mlig455_067134

Neo: Irradiation

Age: -

PPP1R2 0.958 - - - 0.958 - - Mlig455_067134 {REF} {Length: 2837} {TRANSSPLICED} {Pfam: Protein phosphatase inhibitor 2 (IPP-2) [PF04979.16, score=107.7]} {Human: ENSG00000184203, PPP1R2, protein phosphatase 1 regulatory inhibitor subunit 2, [RH, Score=101, Expect=3e-26]} {Mouse: ENSMUSG00000047714, Ppp1r2, protein phosphatase 1, regulatory inhibitor subunit 2, [RH, Score=91.3, Expect=1e-22]} {Dmel: FBgn0028429, I-2, Inhibitor-2, [RH, Score=73.6, Expect=4e-16]} {Celegans: WBGene00021312, szy-2, Suppressor of ZYg-1, [RH, Score=92.8, Expect=2e-23]} {Smed: dd_Smed_v6_5135_0_1, dd_Smed_v6_5135_0_1, [RH, Score=72.4, Expect=4e-16]} {RNA1509_24723, RNA1509_51446, RNA1509_56353} {RNA1310_40287, RNA1509_24723, RNA1509_51446, RNA1509_56353} {RNA1509_24723, RNA1509_51446, RNA1509_56353, RNA815_26897}
30. MligTC455_49004 1711 35.64 Mlig455_040452, Mlig455_042848, Mlig455_043610

Neo: -

Age: logFC(26M/2M)=-0.274

Region-enriched R2: 1.355/0.00285

CCDC180 0.958 - - - 0.958 - -

Mlig455_040452 {REF} {Length: 5565} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4455) [PF14643.8, score=418.0]; Domain of unknown function (DUF4456) [PF14644.8, score=172.8]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [Score=410, Expect=3e-117]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [RH, Score=275, Expect=3e-74]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [Score=399, Expect=4e-116]} {RNA1509_8832} {RNA1310_898.2} {RNA815_672.1}

Mlig455_042848 {REF} {Length: 5466} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4455) [PF14643.8, score=419.7]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [Score=274, Expect=1e-74]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [RH, Score=275, Expect=4e-75]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [Score=254, Expect=7e-69]} {RNA1509_8832} {RNA1310_898.1} {RNA815_672.1}

Mlig455_043610 {REF} {Length: 5567} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4455) [PF14643.8, score=413.1]; Domain of unknown function (DUF4456) [PF14644.8, score=171.2]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [RH, Score=405, Expect=1e-115]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [RH, Score=270, Expect=7e-73]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [RH, Score=398, Expect=1e-115]} {RNA1509_8832} {RNA1310_898.2} {RNA815_672.1}
31. MligTC455_20340 97 2.02 Mlig455_011026, Mlig455_049209

Neo: -

Age: -

0.957 - - 0.957 - - -

Mlig455_011026 {REF} {Length: 124} {NoTransDecoderORF} {RNA1509_50783} {RNA1310_2608}

Mlig455_049209 {REF} {Length: 7414} {RNA1509_53062} {RNA1310_2608} {RNA815_1620}
32. MligTC455_47312 355 7.4 Mlig455_010188

Neo: -

Age: Up-Down-Down

LUC7L 0.956 - - - 0.956 - - Mlig455_010188 {REF} {Length: 2587} {Pfam: LUC7 N_terminus [PF03194.17, score=239.6]} {Human: ENSG00000007392, LUC7L, LUC7 like, [RH, Score=304, Expect=5e-99]; ENSG00000146963, LUC7L2, LUC7 like 2, pre-mRNA splicing factor, [RH, Score=293, Expect=9e-95]} {Mouse: ENSMUSG00000024188, Luc7l, Luc7-like, [RH, Score=303, Expect=9e-99]; ENSMUSG00000029823, Luc7l2, LUC7-like 2 (S. cerevisiae), [RH, Score=290, Expect=3e-94]} {Dmel: FBgn0036734, CG7564, [RH, Score=306, Expect=2e-99]} {Celegans: WBGene00015207, B0495.8, [RH, Score=161, Expect=3e-45]} {Smed: dd_Smed_v6_4536_0_4, dd_Smed_v6_4536_0_4, [RH, Score=300, Expect=3e-99]} {RNA1509_894} {RNA1310_9024.1} {RNA815_807.1}
33. MligTC455_31948 70 1.45 Mlig455_007378, Mlig455_013863, Mlig455_017814, Mlig455_029704

Neo: -

Age: -

KCTD1 0.955 - - 0.955 - - -

Mlig455_007378 {REF} {Length: 1142} {TRANSSPLICED} {Human: ENSG00000134504, KCTD1, potassium channel tetramerization domain containing 1, [Score=69.3, Expect=4e-12]} {Mouse: ENSMUSG00000036225, Kctd1, potassium channel tetramerisation domain containing 1, [Score=69.3, Expect=2e-12]} {RNA1310_16403.1} {RNA815_36960}

Mlig455_013863 {REF} {Length: 108} {NoTransDecoderORF} {RNA1509_35604} {RNA1310_61034} {RNA815_12032.1}

Mlig455_017814 {REF} {Length: 2652} {Human: ENSG00000134504, KCTD1, potassium channel tetramerization domain containing 1, [Score=72.0, Expect=8e-13]} {Mouse: ENSMUSG00000036225, Kctd1, potassium channel tetramerisation domain containing 1, [Score=72.4, Expect=5e-13]} {RNA1509_35604} {RNA1310_16403.1} {RNA815_36960}

Mlig455_029704 {REF} {Length: 726} {Human: ENSG00000134504, KCTD1, potassium channel tetramerization domain containing 1, [Score=50.8, Expect=9e-07]} {Mouse: ENSMUSG00000036225, Kctd1, potassium channel tetramerisation domain containing 1, [Score=50.8, Expect=7e-07]} {RNA1310_16403.1} {RNA815_43647}
34. MligTC455_16034 544 11.33 Mlig455_061559

Neo: -

Age: -

Region-enriched R8: 4.432/0.00000
Region-enriched R7: 2.838/0.00242

CASP7 0.954 - - 0.954 - - - Mlig455_061559 {REF} {Length: 5521} {Pfam: Caspase domain [PF00656.24, score=76.9]} {Human: ENSG00000165806, CASP7, caspase 7, [Score=85.1, Expect=5e-17]; ENSG00000003400, CASP10, caspase 10, [Score=81.3, Expect=3e-15]; ENSG00000164305, CASP3, caspase 3, [Score=80.9, Expect=5e-16]} {Mouse: ENSMUSG00000025076, Casp7, caspase 7, [Score=82.8, Expect=1e-16]; ENSMUSG00000031628, Casp3, caspase 3, [Score=80.1, Expect=6e-16]} {Dmel: FBgn0019972, Drice, Death related ICE-like caspase, [Score=75.1, Expect=4e-14]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=82.8, Expect=4e-17]} {Smed: dd_Smed_v6_1167_0_1, dd_Smed_v6_1167_0_1, [Score=89.4, Expect=1e-19]} {RNA1509_47042} {RNA1310_6014.2, RNA1509_47042} {RNA1509_47042, RNA815_17780}
35. MligTC455_19220 195 4.06 Mlig455_000118

Neo: -

Age: -

GUCY2D 0.954 - - - 0.954 - - Mlig455_000118 {REF} {Length: 4501} {Pfam: PBP superfamily domain [PF12849.9, score=114.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=86.4]; Protein kinase domain [PF00069.27, score=85.7]; Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=27.6]} {Human: ENSG00000132518, GUCY2D, guanylate cyclase 2D, retinal, [Score=140, Expect=7e-33]} {Mouse: ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=144, Expect=3e-34]} {Dmel: FBgn0051183, CG31183, [Score=159, Expect=6e-39]} {Celegans: WBGene00001531, gcy-4, Receptor-type guanylate cyclase gcy-4, [Score=135, Expect=9e-32]} {Smed: dd_Smed_v6_7644_0_1, dd_Smed_v6_7644_0_1, [Score=138, Expect=8e-33]} {RNA1310_30282} {RNA815_47191}
36. MligTC455_31554 12688 264.32 Mlig455_003094

Neo: -

Age: Down-Up-Down

Region-enriched R4: 2.454/0.01927

0.954 - - - - 0.954 - Mlig455_003094 {REF} {Length: 2681} {Pfam: Wolframin Sel1-like repeat [PF20023.1, score=52.7]; Crp-like helix-turn-helix domain [PF13545.8, score=50.3]; 4'-phosphopantetheinyl transferase superfamily [PF01648.22, score=47.0]; Family of unknown function (DUF6307) [PF19826.1, score=42.0]; MarR family [PF01047.24, score=38.3]; Ribosomal protein L10 [PF00466.22, score=38.1]; Skp1 family, tetramerisation domain [PF03931.17, score=35.7]; PASTA domain [PF03793.21, score=32.0]; Family of unknown function (DUF6470) [PF20074.1, score=32.0]; D-lactate dehydrogenase, membrane binding [PF09330.13, score=30.1]; SprT-like family [PF10263.11, score=26.5]; winged helix-turn-helix [PF16221.7, score=26.3]; CUT domain [PF02376.17, score=24.1]; Helicase HerA, central domain [PF01935.19, score=22.5]; Bpu10I restriction endonuclease [PF09549.12, score=22.1]; von Willebrand factor type A domain [PF13768.8, score=21.6]; Protein of unknown function (DUF1340) [PF07067.13, score=21.0]; Mobile element transfer protein [PF05122.15, score=18.8]} {RNA1509_27680} {RNA1310_14862.1} {RNA815_5816}
37. MligTC455_35191 501 10.43 Mlig455_053755

Neo: -

Age: -

Region-enriched R7: 2.882/0.00002

ASTE1 0.954 - - - 0.954 - - Mlig455_053755 {REF} {Length: 4221} {TRANSSPLICED} {Pfam: XPG domain containing [PF12813.9, score=40.2]; XPG N-terminal domain [PF00752.19, score=29.6]} {Human: ENSG00000034533, ASTE1, asteroid homolog 1, [Score=111, Expect=7e-25]} {Mouse: ENSMUSG00000032567, Aste1, asteroid homolog 1, [Score=97.4, Expect=1e-20]} {Dmel: FBgn0015905, ast, asteroid, [Score=89.4, Expect=3e-18]} {Smed: dd_Smed_v6_12690_0_1, dd_Smed_v6_12690_0_1, [RH, Score=139, Expect=1e-34]} {RNA1509_21473} {RNA1310_12314.1, RNA1509_21473} {RNA1509_21473, RNA815_6412}
38. MligTC455_42736 407 8.48 Mlig455_003009, Mlig455_036418, Mlig455_054591

Neo: -

Age: -

0.954 - - 0.954 - - -

Mlig455_003009 {REF} {Length: 2844} {RNA1509_52803} {RNA1310_21149.1, RNA1509_52803} {RNA1509_52803, RNA815_36125.1}

Mlig455_036418 {REF} {Length: 1808} {RNA1509_52803} {RNA1310_21149.1} {RNA815_36125.1}

Mlig455_054591 {REF} {Length: 1603} {RNA1509_52803} {RNA1310_21149.1} {RNA815_36125.1}
39. MligTC455_53717 578 12.04 Mlig455_008875

Neo: -

Age: -

PPP3R1 0.954 - - - 0.954 - - Mlig455_008875 {REF} {Length: 2064} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=93.1]; EF-hand domain pair [PF13499.8, score=90.1]; EF-hand domain [PF13405.8, score=77.2]; EF hand [PF13202.8, score=68.5]; EF-hand domain pair [PF13833.8, score=58.7]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=30.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=30.7]; EF-hand domain [PF14658.8, score=25.5]} {Human: ENSG00000221823, PPP3R1, protein phosphatase 3 regulatory subunit B, alpha, [RH, Score=285, Expect=2e-99]} {Mouse: ENSMUSG00000033953, Ppp3r1, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I), [RH, Score=285, Expect=1e-99]} {Dmel: FBgn0010014, CanB, Calcineurin B, [RH, Score=277, Expect=6e-97]} {Celegans: WBGene00000554, cnb-1, Protein phosphatase 2B regulatory subunit cnb-1, [RH, Score=264, Expect=1e-91]} {Smed: dd_Smed_v6_4924_0_1, dd_Smed_v6_4924_0_1, [RH, Score=292, Expect=4e-103]} {RNA1509_4591} {RNA1310_15040.1, RNA1509_4591} {RNA1509_4591, RNA815_13445.1}
40. MligTC455_28702 789 16.43 Mlig455_021393

Neo: -

Age: logFC(26M/2M)=0.303

CLTC 0.953 - - - 0.953 - - Mlig455_021393 {REF} {Length: 7603} {Pfam: Region in Clathrin and VPS [PF00637.22, score=638.4]; Clathrin propeller repeat [PF01394.22, score=136.0]; Clathrin-H-link [PF13838.8, score=108.9]; Clathrin, heavy-chain linker [PF09268.12, score=45.8]; Coatomer WD associated region [PF04053.16, score=31.1]} {Human: ENSG00000141367, CLTC, clathrin heavy chain, [RH, Score=2731, Expect=0.0]} {Mouse: ENSMUSG00000047126, Cltc, clathrin, heavy polypeptide (Hc), [RH, Score=2731, Expect=0.0]} {Dmel: FBgn0000319, Chc, Clathrin heavy chain, [RH, Score=2615, Expect=0.0]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [RH, Score=2412, Expect=0.0]} {Smed: dd_Smed_v6_59_0_1, dd_Smed_v6_59_0_1, [RH, Score=2760, Expect=0.0]} {RNA1509_14831} {RNA1310_1023.1} {RNA815_198.1}
41. MligTC455_39150 726 15.13 Mlig455_059875

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.318

0.953 - - - 0.953 - - Mlig455_059875 {REF} {Length: 1197} {RNA1509_37037} {RNA1310_1872.1, RNA1509_37037} {RNA1509_37037, RNA815_585.4}
42. MligTC455_39379 396 8.25 Mlig455_051141, Mlig455_063002, Mlig455_063025

Neo: -

Age: -

0.953 - - - 0.953 - -

Mlig455_051141 {REF} {Length: 679} {NoTransDecoderORF} {RNA1310_60644} {RNA815_33881}

Mlig455_063002 {REF} {Length: 1074} {NoTransDecoderORF} {RNA1310_60644} {RNA815_33881}

Mlig455_063025 {REF} {Length: 662} {NoTransDecoderORF} {RNA1310_60644} {RNA815_33881}
43. MligTC455_53459 612 12.75 Mlig455_019124

Neo: -

Age: -

MAGI2 0.953 - - - 0.953 - - Mlig455_019124 {REF} {Length: 6958} {Pfam: PDZ domain [PF00595.26, score=176.3]; PDZ domain [PF17820.3, score=100.9]; PDZ domain [PF13180.8, score=70.3]; Guanylate kinase [PF00625.23, score=37.0]; WW domain [PF00397.28, score=32.4]; Family of unknown function (DUF6288) [PF19805.1, score=18.9]} {Human: ENSG00000187391, MAGI2, membrane associated guanylate kinase, WW and PDZ domain containing 2, [RH, Score=340, Expect=4e-97]} {Mouse: ENSMUSG00000040003, Magi2, membrane associated guanylate kinase, WW and PDZ domain containing 2, [RH, Score=347, Expect=2e-99]} {Dmel: FBgn0034590, Magi, [Score=199, Expect=2e-51]} {Celegans: WBGene00010444, magi-1, MAGI (Membrane Associated Guanylate kinase Inverted) homolog, [RH, Score=290, Expect=2e-81]} {Smed: dd_Smed_v6_854_0_3, dd_Smed_v6_854_0_3, [Score=421, Expect=1e-126]} {RNA1509_27534, RNA1509_46402} {RNA1310_6901, RNA1509_27534} {RNA1509_27534, RNA815_13787}
44. MligTC455_20064 1169 24.35 Mlig455_000647

Neo: -

Age: -

GRB2 0.952 - - - 0.952 - - Mlig455_000647 {REF} {Length: 3000} {TRANSSPLICED} {Pfam: Variant SH3 domain [PF14604.8, score=117.8]; SH3 domain [PF00018.30, score=105.0]; Variant SH3 domain [PF07653.19, score=104.0]; SH2 domain [PF00017.26, score=65.5]} {Human: ENSG00000177885, GRB2, growth factor receptor bound protein 2, [RH, Score=205, Expect=5e-66]} {Mouse: ENSMUSG00000059923, Grb2, growth factor receptor bound protein 2, [RH, Score=204, Expect=8e-66]} {Dmel: FBgn0004638, drk, downstream of receptor kinase, [RH, Score=211, Expect=6e-69]} {Celegans: WBGene00004774, sem-5, Sex muscle abnormal protein 5, [RH, Score=214, Expect=7e-70]} {Smed: dd_Smed_v6_4190_0_1, dd_Smed_v6_4190_0_1, [RH, Score=226, Expect=7e-75]} {RNA1509_52820, RNA1509_7263} {RNA1310_20298.2, RNA1509_52820, RNA1509_7263} {RNA1509_52820, RNA1509_7263, RNA815_19049}
45. MligTC455_49646 739 15.39 Mlig455_067640

Neo: -

Age: -

MEF2D 0.952 - - - 0.952 - - Mlig455_067640 {REF} {Length: 5061} {TRANSSPLICED} {Pfam: SRF-type transcription factor (DNA-binding and dimerisation domain) [PF00319.20, score=87.0]} {Human: ENSG00000116604, MEF2D, myocyte enhancer factor 2D, [Score=171, Expect=2e-50]; ENSG00000213999, MEF2B, myocyte enhancer factor 2B, [Score=170, Expect=3e-51]; ENSG00000064489, BORCS8-MEF2B, BORCS8-MEF2B readthrough, [Score=170, Expect=3e-51]; ENSG00000068305, MEF2A, myocyte enhancer factor 2A, [Score=167, Expect=3e-49]; ENSG00000081189, MEF2C, myocyte enhancer factor 2C, [Score=166, Expect=1e-52]} {Mouse: ENSMUSG00000001419, Mef2d, myocyte enhancer factor 2D, [Score=171, Expect=1e-50]; ENSMUSG00000030557, Mef2a, myocyte enhancer factor 2A, [Score=167, Expect=2e-49]; ENSMUSG00000005583, Mef2c, myocyte enhancer factor 2C, [Score=166, Expect=4e-53]} {Dmel: FBgn0011656, Mef2, Myocyte enhancer factor 2, [Score=162, Expect=3e-47]} {Celegans: WBGene00003182, mef-2, Related to vertebrate MEF2 transcription factor, [Score=174, Expect=2e-53]} {Smed: dd_Smed_v6_6889_0_1, dd_Smed_v6_6889_0_1, [Score=152, Expect=4e-44]} {RNA1509_58067, RNA1509_8265} {RNA1310_21974.1, RNA1509_58067, RNA1509_8265} {RNA1509_58067, RNA1509_8265, RNA815_4359.2}
46. MligTC455_27914 110 2.29 Mlig455_041696

Neo: -

Age: -

0.951 - - - 0.951 - - Mlig455_041696 {REF} {Length: 2609} {NoTransDecoderORF} {RNA1509_48204} {RNA1310_38888.1} {RNA815_62436}
47. MligTC455_10159 784 16.34 Mlig455_058301

Neo: -

Age: -

0.95 - - - 0.950 - - Mlig455_058301 {REF} {Length: 5127} {TRANSSPLICED} {Pfam: RUN domain [PF02759.21, score=56.1]} {Mouse: ENSMUSG00000035969, Rusc2, RUN and SH3 domain containing 2, [RH, Score=74.3, Expect=9e-13]} {Smed: dd_Smed_v6_4870_0_1, dd_Smed_v6_4870_0_1, [Score=83.6, Expect=4e-16]} {RNA1509_15377} {RNA1310_3986.1} {RNA815_14075.1}
48. MligTC455_20745 401 8.36 Mlig455_030491

Neo: -

Age: -

TNIK 0.95 - - - 0.950 - - Mlig455_030491 {REF} {Length: 5161} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=209.8]; CNH domain [PF00780.24, score=179.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=155.9]; ABC1 atypical kinase-like domain [PF03109.18, score=31.6]; Fungal protein kinase [PF17667.3, score=22.4]} {Human: ENSG00000154310, TNIK, TRAF2 and NCK interacting kinase, [RH, Score=501, Expect=2e-153]} {Mouse: ENSMUSG00000027692, Tnik, TRAF2 and NCK interacting kinase, [RH, Score=501, Expect=5e-154]; ENSMUSG00000020827, Mink1, misshapen-like kinase 1 (zebrafish), [RH, Score=476, Expect=1e-144]} {Dmel: FBgn0010909, msn, misshapen, [RH, Score=504, Expect=2e-153]} {Celegans: WBGene00003247, mig-15, Serine/threonine-protein kinase mig-15, [RH, Score=502, Expect=1e-156]} {Smed: dd_Smed_v6_1029_0_1, dd_Smed_v6_1029_0_1, [RH, Score=442, Expect=8e-136]} {RNA1509_5951} {RNA1310_3546} {RNA815_5720.1}
49. MligTC455_23384 525 10.94 Mlig455_066524

Neo: -

Age: -

SLC9A3R1 0.95 - - - - 0.950 - Mlig455_066524 {REF} {Length: 2437} {Pfam: PDZ domain [PF00595.26, score=45.5]; PDZ domain [PF17820.3, score=40.0]; PDZ domain [PF13180.8, score=22.7]} {Human: ENSG00000109062, SLC9A3R1, SLC9A3 regulator 1, [RH, Score=100, Expect=3e-25]; ENSG00000065054, SLC9A3R2, SLC9A3 regulator 2, [RH, Score=96.3, Expect=2e-23]} {Mouse: ENSMUSG00000020733, Slc9a3r1, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1, [RH, Score=100, Expect=4e-24]; ENSMUSG00000002504, Slc9a3r2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, [RH, Score=99.0, Expect=2e-24]} {Dmel: FBgn0010620, CG10939, [RH, Score=96.7, Expect=4e-23]} {Celegans: WBGene00006438, nrfl-1, NHERF (Mammalian Na/H Exchange Regulatory Factor) Like, [Score=103, Expect=2e-25]} {Smed: dd_Smed_v6_3039_0_1, dd_Smed_v6_3039_0_1, [RH, Score=122, Expect=4e-34]} {RNA1509_22721} {RNA1310_24483, RNA1509_22721} {RNA1509_22721, RNA815_13202}
50. MligTC455_33700 888 18.5 Mlig455_007054

Neo: -

Age: logFC(26M/2M)=0.242

SACS 0.95 - - - 0.950 - - Mlig455_007054 {REF} {Length: 10881} {TRANSSPLICED} {Pfam: HEPN domain [PF05168.16, score=40.4]} {Human: ENSG00000151835, SACS, sacsin molecular chaperone, [Score=656, Expect=0.0]} {Mouse: ENSMUSG00000048279, Sacs, sacsin, [RH, Score=648, Expect=0.0]} {RNA1509_13851, RNA1509_2130, RNA1509_30347, RNA1509_42675} {RNA1310_137.1, RNA1509_13851, RNA1509_30347, RNA1509_42675} {RNA1509_13851, RNA1509_30347, RNA1509_42675, RNA815_91}

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