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Results for MligTC455_47220

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_47220 1734 36.13 Mlig455_052994

Neo: -

Age: -

 PCSK4 Mlig455_052994 {REF} {Length: 3592} {TRANSSPLICED} {Pfam: Subtilase family [PF00082.24, score=139.0]; Proprotein convertase P-domain [PF01483.22, score=45.6]; Peptidase S8 pro-domain [PF16470.7, score=30.2]} {Human: ENSG00000115257, PCSK4, proprotein convertase subtilisin/kexin type 4, [Score=369, Expect=4e-116]; ENSG00000175426, PCSK1, proprotein convertase subtilisin/kexin type 1, [Score=353, Expect=2e-110]} {Mouse: ENSMUSG00000020131, Pcsk4, proprotein convertase subtilisin/kexin type 4, [Score=356, Expect=1e-112]; ENSMUSG00000021587, Pcsk1, proprotein convertase subtilisin/kexin type 1, [Score=353, Expect=3e-110]; ENSMUSG00000027419, Pcsk2, proprotein convertase subtilisin/kexin type 2, [Score=343, Expect=9e-108]} {Dmel: FBgn0004598, Fur2, Furin 2, [Score=337, Expect=2e-99]} {Celegans: WBGene00002232, kpc-1, Furin-like protease kpc-1, [Score=362, Expect=1e-114]} {Smed: dd_Smed_v6_8406_0_3, dd_Smed_v6_8406_0_3, [Score=318, Expect=7e-99]} {RNA1509_30392, RNA1509_3476, RNA1509_44487} {RNA1310_9937, RNA1509_30392, RNA1509_3476, RNA1509_44487} {RNA1509_30392, RNA1509_3476, RNA1509_44487, RNA815_2907}

Cumulative graph for MligTC455_47220

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.44 5.135 0.61871 1.00000
RegionR2 0.542 5.135 0.19093 0.54675
RegionR3 0.315 5.135 0.37795 0.91111
RegionR4 0.572 5.135 0.20907 0.49311
RegionR5 -0.237 5.135 0.52564 0.88800
RegionR6 -0.007 5.135 0.98636 1.00000
RegionR7 -0.373 5.135 0.40566 1.00000
RegionR8 -0.372 5.135 0.46358 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.308 5.135 0.19115 0.93000
RegenerationR2 -0.05 5.135 0.90115 1.00000
RegenerationR3 0.279 5.135 0.51775 0.86539
RegenerationR4 0.049 5.135 0.91571 1.00000
RegenerationR5 0.144 5.135 0.74324 0.96965
RegenerationR6 -0.293 5.135 0.52264 0.82220
RegenerationBL -1.015 5.135 0.05041 0.25860
RegenerationTP 0.169 5.135 0.73307 1.00000


Genes with expression patterns similar to MligTC455_47220

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_47220 1734 36.13 Mlig455_052994

Neo: -

Age: -

 PCSK4 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_052994 {REF} {Length: 3592} {TRANSSPLICED} {Pfam: Subtilase family [PF00082.24, score=139.0]; Proprotein convertase P-domain [PF01483.22, score=45.6]; Peptidase S8 pro-domain [PF16470.7, score=30.2]} {Human: ENSG00000115257, PCSK4, proprotein convertase subtilisin/kexin type 4, [Score=369, Expect=4e-116]; ENSG00000175426, PCSK1, proprotein convertase subtilisin/kexin type 1, [Score=353, Expect=2e-110]} {Mouse: ENSMUSG00000020131, Pcsk4, proprotein convertase subtilisin/kexin type 4, [Score=356, Expect=1e-112]; ENSMUSG00000021587, Pcsk1, proprotein convertase subtilisin/kexin type 1, [Score=353, Expect=3e-110]; ENSMUSG00000027419, Pcsk2, proprotein convertase subtilisin/kexin type 2, [Score=343, Expect=9e-108]} {Dmel: FBgn0004598, Fur2, Furin 2, [Score=337, Expect=2e-99]} {Celegans: WBGene00002232, kpc-1, Furin-like protease kpc-1, [Score=362, Expect=1e-114]} {Smed: dd_Smed_v6_8406_0_3, dd_Smed_v6_8406_0_3, [Score=318, Expect=7e-99]} {RNA1509_30392, RNA1509_3476, RNA1509_44487} {RNA1310_9937, RNA1509_30392, RNA1509_3476, RNA1509_44487} {RNA1509_30392, RNA1509_3476, RNA1509_44487, RNA815_2907}
2. MligTC455_47221 2304 47.99 Mlig455_053054

Neo: -

Age: -

 PCSK4 4.736 - 0.866 0.919 0.979 0.977 0.995 Mlig455_053054 {REF} {Length: 2790} {Pfam: Subtilase family [PF00082.24, score=113.4]; Proprotein convertase P-domain [PF01483.22, score=45.5]} {Human: ENSG00000115257, PCSK4, proprotein convertase subtilisin/kexin type 4, [Score=304, Expect=1e-94]} {Mouse: ENSMUSG00000020131, Pcsk4, proprotein convertase subtilisin/kexin type 4, [Score=290, Expect=1e-90]; ENSMUSG00000024713, Pcsk5, proprotein convertase subtilisin/kexin type 5, [Score=288, Expect=3e-85]; ENSMUSG00000030530, Furin, furin (paired basic amino acid cleaving enzyme), [Score=280, Expect=2e-85]} {Dmel: FBgn0004509, Fur1, Furin 1, [Score=266, Expect=7e-80]} {Celegans: WBGene00002232, kpc-1, Furin-like protease kpc-1, [Score=301, Expect=1e-94]} {Smed: dd_Smed_v6_8406_0_2, dd_Smed_v6_8406_0_2, [Score=264, Expect=3e-81]} {RNA1509_21248, RNA1509_3476} {RNA1310_9937, RNA1509_21248} {RNA1509_21248, RNA815_2907}
3. MligTC455_51029 340 7.09 Mlig455_056736

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.541

 3.615 - 0.908 0.864 0.877 0.966 - Mlig455_056736 {REF} {Length: 850} {RNA1509_4527} {RNA1310_27536} {RNA815_19650}
4. MligTC455_10599 140 2.91 Mlig455_000565, Mlig455_030365, Mlig455_030412

Neo: -

Age: logFC(26M/2M)=-0.762

 GRIK3 3.516 - 0.868 0.820 0.971 0.857 -

Mlig455_000565 {REF} {Length: 2846} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=72.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=56.1]; Ligand-gated ion channel [PF00060.28, score=44.5]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=145, Expect=3e-35]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=142, Expect=3e-34]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=141, Expect=5e-34]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=139, Expect=3e-33]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=144, Expect=5e-35]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=143, Expect=1e-34]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=140, Expect=9e-34]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=139, Expect=2e-33]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=138, Expect=5e-33]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=138, Expect=4e-33]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=130, Expect=1e-30]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=135, Expect=3e-32]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=154, Expect=2e-38]} {RNA1509_59839} {RNA1310_4586} {RNA815_2154.1}

Mlig455_030365 {REF} {Length: 2765} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=72.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=57.7]; Ligand-gated ion channel [PF00060.28, score=43.6]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=144, Expect=6e-35]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=140, Expect=2e-33]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=138, Expect=7e-33]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=138, Expect=7e-33]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=137, Expect=2e-32]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=142, Expect=2e-34]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=142, Expect=2e-34]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=138, Expect=4e-33]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=136, Expect=2e-32]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=136, Expect=2e-32]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=130, Expect=6e-31]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=131, Expect=3e-31]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=155, Expect=7e-39]} {RNA1509_59839} {RNA1310_4586} {RNA815_2154.1}

Mlig455_030412 {REF} {Length: 2615} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=72.2]; Ligand-gated ion channel [PF00060.28, score=45.1]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=36.1]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=125, Expect=6e-29]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=122, Expect=6e-28]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=121, Expect=1e-27]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=125, Expect=4e-29]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=124, Expect=6e-29]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=120, Expect=2e-27]} {Dmel: FBgn0026255, clumsy, [Score=117, Expect=9e-27]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=117, Expect=7e-27]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=135, Expect=1e-32]} {RNA1509_59839} {RNA1310_4586} {RNA815_2154.1}
5. MligTC455_33877 47 0.97 Mlig455_053914

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.540

 PKD1L2 3.494 - 0.799 0.842 0.952 0.901 - Mlig455_053914 {REF} {Length: 11153} {Pfam: Polycystin cation channel [PF08016.14, score=263.3]; PKD domain [PF18911.2, score=78.1]; PLAT/LH2 domain [PF01477.25, score=77.6]; PKD domain [PF00801.22, score=77.5]; REJ domain [PF02010.17, score=51.1]; Ion transport protein [PF00520.33, score=32.5]} {Human: ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [Score=236, Expect=4e-61]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=254, Expect=1e-66]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=132, Expect=3e-30]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=134, Expect=1e-30]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=451, Expect=4e-127]} {RNA1509_40400} {RNA1310_23183} {RNA815_27645}
6. MligTC455_27683 1046 21.8 Mlig455_027300

Neo: -

Age: Down-Up-Down

Regeneration-downregulated R2: -3.093

Regeneration-depleted R2: -3.093

 3.428 - 0.851 0.821 - 0.782 0.974 Mlig455_027300 {REF} {Length: 786} {RNA1509_20033} {RNA1310_17576.1} {RNA815_6182.1}
7. MligTC455_46043 62 1.3 Mlig455_042332

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.745

 3.395 - 0.764 0.808 0.865 0.958 - Mlig455_042332 {REF} {Length: 1761} {Pfam: WSC domain [PF01822.21, score=47.9]; PAN domain [PF00024.28, score=19.6]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=46.2, Expect=8e-06]} {RNA1509_32911} {RNA1310_59750} {RNA815_37535}
8. MligTC455_24390 450 9.38 Mlig455_020500, Mlig455_020536, Mlig455_020584

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.736

Region-enriched R2: 5.381/0.00082
Region-enriched R3: 4.387/0.00015

 2.758 - - 0.891 0.887 0.980 -

Mlig455_020500 {REF} {Length: 2831} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=53.4]} {Smed: dd_Smed_v6_11922_0_1, dd_Smed_v6_11922_0_1, [RH, Score=155, Expect=2e-44]} {RNA1509_39737, RNA1509_43214} {RNA1310_27522, RNA1509_43214} {RNA1509_43214, RNA815_12084}

Mlig455_020536 {REF} {Length: 1340} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=54.4]} {Smed: dd_Smed_v6_11922_0_1, dd_Smed_v6_11922_0_1, [RH, Score=156, Expect=7e-45]} {RNA1509_39737} {RNA1310_27522, RNA1509_39737} {RNA1509_39737, RNA815_12084}

Mlig455_020584 {REF} {Length: 1603} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=53.2]} {Smed: dd_Smed_v6_11922_0_1, dd_Smed_v6_11922_0_1, [RH, Score=149, Expect=4e-42]} {RNA1509_43214} {RNA1310_27522} {RNA815_12084}
9. MligTC455_37724 781 16.28 Mlig455_065465

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.698

 ROR1 2.63 - 0.754 - 0.890 - 0.986 Mlig455_065465 {REF} {Length: 4059} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=240.2]; Protein kinase domain [PF00069.27, score=101.6]; Immunoglobulin I-set domain [PF07679.18, score=45.2]; Immunoglobulin domain [PF13927.8, score=42.8]; Fz domain [PF01392.24, score=34.0]; Immunoglobulin domain [PF13895.8, score=32.3]; Immunoglobulin domain [PF00047.27, score=24.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=398, Expect=5e-123]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=402, Expect=6e-125]} {Dmel: FBgn0010407, Ror, [Score=276, Expect=1e-80]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=220, Expect=1e-59]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=398, Expect=3e-124]} {RNA1509_15729, RNA1509_49184} {RNA1310_2781.1, RNA1509_15729, RNA1509_49184} {RNA1509_15729, RNA1509_49184, RNA815_11745}
10. MligTC455_15767 171 3.56 Mlig455_051560

Neo: -

Age: logFC(26M/2M)=-0.461

Region-enriched R2: 2.630/0.01388

 2.601 - - 0.758 0.854 - 0.989 Mlig455_051560 {REF} {Length: 3535} {RNA1509_39932} {RNA1310_8880.1} {RNA815_43831}
11. MligTC455_51262 384 7.99 Mlig455_036989

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.021

Region-enriched R3: 4.958/0.00000
Region-enriched R2: 4.046/0.01134

 2.562 - - 0.798 0.958 0.806 - Mlig455_036989 {REF} {Length: 1396} {Pfam: Universal stress protein family [PF00582.28, score=85.7]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=97.4, Expect=8e-26]} {RNA1310_30400} {RNA815_28361}
12. MligTC455_47481 208 4.33 Mlig455_066050

Neo: -

Age: -

Region-enriched R2: 3.601/0.00192

 2.55 - 0.738 - 0.820 - 0.992 Mlig455_066050 {REF} {Length: 1418} {RNA1310_25309} {RNA815_22558.1}
13. MligTC455_51260 90 1.88 Mlig455_009349

Neo: -

Age: -

 2.526 - 0.765 0.803 0.958 - - Mlig455_009349 {REF} {Length: 1657} {Pfam: Universal stress protein family [PF00582.28, score=83.5]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=97.8, Expect=2e-24]} {RNA1310_30400} {RNA815_28361}
14. MligTC455_26553 214 4.45 Mlig455_055245

Neo: -

Age: -

 FOXP4 2.479 - - 0.718 0.774 - 0.987 Mlig455_055245 {REF} {Length: 4222} {Pfam: Forkhead domain [PF00250.20, score=92.5]; FOXP coiled-coil domain [PF16159.7, score=60.0]; Citrate transporter [PF03600.18, score=18.7]} {Human: ENSG00000137166, FOXP4, forkhead box P4, [RH, Score=191, Expect=4e-52]; ENSG00000128573, FOXP2, forkhead box P2, [RH, Score=186, Expect=3e-50]} {Mouse: ENSMUSG00000023991, Foxp4, forkhead box P4, [RH, Score=206, Expect=1e-57]; ENSMUSG00000116496, Foxp4, forkhead box P4, [RH, Score=206, Expect=1e-57]} {Dmel: FBgn0262477, FoxP, Forkhead box P, [RH, Score=217, Expect=6e-64]} {Celegans: WBGene00001439, fkh-7, ForKHead transcription factor family, [RH, Score=196, Expect=6e-54]} {Smed: dd_Smed_v6_6316_0_1, dd_Smed_v6_6316_0_1, [RH, Score=113, Expect=2e-26]} {RNA1509_18798} {RNA1310_9496.1, RNA1509_18798} {RNA1509_18798, RNA815_1593}
15. MligTC455_01243 37 0.77 Mlig455_055650

Neo: -

Age: -

 2.467 - 0.763 0.753 0.951 - - Mlig455_055650 {REF} {Length: 625} {Pfam: Universal stress protein family [PF00582.28, score=20.0]} {RNA1310_33871} {RNA815_28361}
16. MligTC455_45597 116 2.41 Mlig455_049417

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.185/0.02405

 2.437 - - 0.777 0.952 0.708 - Mlig455_049417 {REF} {Length: 1106} {RNA1310_45744} {RNA815_56662}
17. MligTC455_43686 326 6.79 Mlig455_022166, Mlig455_055777

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.570

Region-enriched R3: 6.671/0.00000
Region-enriched R2: 5.224/0.01307

 1.936 - - - 0.950 0.986 -

Mlig455_022166 {REF} {Length: 612} {RNA1310_23536} {RNA815_45816}

Mlig455_055777 {REF} {Length: 584} {RNA1310_23536} {RNA815_45816}
18. MligTC455_08096 18 0.37 Mlig455_006571

Neo: -

Age: -

 1.87 - - - 0.951 0.919 - Mlig455_006571 {REF} {Length: 1500} {NoTransDecoderORF} {RNA1509_37481} {RNA1310_1635.1} {RNA815_50336}
19. MligTC455_29881 110 2.29 Mlig455_052119

Neo: -

Age: -

 ANKRD52 1.86 - - - - 0.870 0.990 Mlig455_052119 {REF} {Length: 5912} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=74.6]; Ankyrin repeats (many copies) [PF13637.8, score=56.6]; Ankyrin repeat [PF13606.8, score=46.1]; Ankyrin repeat [PF00023.32, score=43.1]; Ankyrin repeats (many copies) [PF13857.8, score=42.8]; Mab-21 protein [PF03281.16, score=27.0]} {Human: ENSG00000139645, ANKRD52, ankyrin repeat domain 52, [Score=84.3, Expect=1e-15]} {Mouse: ENSMUSG00000014498, Ankrd52, ankyrin repeat domain 52, [Score=84.3, Expect=8e-16]} {Dmel: FBgn0041096, rols, rolling pebbles, [Score=65.1, Expect=5e-10]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=57.4, Expect=9e-08]} {Smed: dd_Smed_v6_7952_0_1, dd_Smed_v6_7952_0_1, [Score=62.4, Expect=2e-09]} {RNA1509_26281} {RNA1310_28428.1} {RNA815_5358.1}
20. MligTC455_28349 319 6.64 Mlig455_024478

Neo: -

Age: logFC(26M/2M)=-0.636

 1.853 - - - - 0.876 0.977 Mlig455_024478 {REF} {Length: 3765} {RNA1509_10739, RNA1509_43075} {RNA1310_4284, RNA1509_10739, RNA1509_43075} {RNA1509_10739, RNA1509_43075, RNA815_18697}
21. MligTC455_22287 217 4.51 Mlig455_061243

Neo: -

Age: -

Region-enriched R6: 2.653/0.03497

 1.834 - - - 0.867 - 0.967 Mlig455_061243 {REF} {Length: 715} {RNA1310_30275.2} {RNA815_15340.1}
22. MligTC455_13098 19 0.4 Mlig455_020992

Neo: -

Age: -

 C1GALT1 1.804 - - - 0.955 0.849 - Mlig455_020992 {REF} {Length: 1108} {Pfam: Galactosyltransferase [PF01762.23, score=27.6]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=160, Expect=3e-46]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=162, Expect=1e-46]} {Dmel: FBgn0032078, C1GalTA, Core 1 Galactosyltransferase A, [Score=138, Expect=8e-38]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=165, Expect=4e-48]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=185, Expect=3e-56]} {RNA1310_125941}
23. MligTC455_31133 98 2.03 Mlig455_071129

Neo: -

Age: -

 ANKRD17 1.788 - 0.805 - - - 0.983 Mlig455_071129 {REF} {Length: 3893} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=145.2]; Ankyrin repeats (many copies) [PF13637.8, score=125.4]; Ankyrin repeat [PF13606.8, score=84.0]; Ankyrin repeats (many copies) [PF13857.8, score=83.2]; Ankyrin repeat [PF00023.32, score=67.3]; Transcription factor BRX N-terminal domain [PF13713.8, score=36.3]; Tc3 transposase [PF11427.10, score=23.1]; Protein of unknown function (DUF3307) [PF11750.10, score=19.5]; Topo homolgy domain in CRISPR-associated endonuclease Cas9 [PF17894.3, score=19.5]} {Human: ENSG00000132466, ANKRD17, ankyrin repeat domain 17, [Score=107, Expect=1e-23]} {Mouse: ENSMUSG00000055204, Ankrd17, ankyrin repeat domain 17, [Score=108, Expect=6e-24]} {Dmel: FBgn0039590, CG10011, [Score=77.8, Expect=2e-14]} {Celegans: WBGene00012124, T28D6.4, [Score=82.8, Expect=3e-16]} {Smed: dd_Smed_v6_5303_0_2, dd_Smed_v6_5303_0_2, [Score=94.7, Expect=4e-20]} {RNA1509_44391} {RNA1310_30238.1} {RNA815_12459}
24. MligTC455_23330 207 4.32 Mlig455_009407, Mlig455_036917

Neo: -

Age: -

 1.781 - - - 0.797 - 0.984

Mlig455_009407 {REF} {Length: 5394} {Pfam: Innexin [PF00876.20, score=328.1]} {Dmel: FBgn0085387, shakB, shaking B, [Score=111, Expect=1e-26]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=220, Expect=2e-67]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=315, Expect=2e-103]} {RNA1509_48973} {RNA1310_18979.1} {RNA815_25805}

Mlig455_036917 {REF} {Length: 6111} {Pfam: Innexin [PF00876.20, score=327.2]} {Dmel: FBgn0085387, shakB, shaking B, [Score=110, Expect=1e-26]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=218, Expect=1e-66]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=318, Expect=9e-105]} {RNA1509_48973} {RNA1310_18979.1, RNA1509_48973} {RNA1509_48973, RNA815_25805}
25. MligTC455_47096 301 6.27 Mlig455_060395

Neo: -

Age: -

 SSUH2 1.774 - 0.805 - - - 0.969 Mlig455_060395 {REF} {Length: 2019} {Pfam: DnaJ central domain [PF00684.21, score=23.3]} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=110, Expect=1e-26]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=87.4, Expect=9e-19]} {RNA1509_22065} {RNA1310_14684} {RNA815_5263.1}
26. MligTC455_20727 1028 21.42 Mlig455_035301

Neo: -

Age: Down-Down-Up

Region-enriched R2: 2.704/0.02006

 SLC1A6 1.773 - - - 0.813 - 0.960 Mlig455_035301 {REF} {Length: 2540} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=411.5]} {Human: ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [RH, Score=477, Expect=3e-163]; ENSG00000079215, SLC1A3, solute carrier family 1 member 3, [RH, Score=471, Expect=4e-161]; ENSG00000106688, SLC1A1, solute carrier family 1 member 1, [RH, Score=456, Expect=2e-155]} {Mouse: ENSMUSG00000005357, Slc1a6, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, [RH, Score=474, Expect=2e-162]; ENSMUSG00000005360, Slc1a3, solute carrier family 1 (glial high affinity glutamate transporter), member 3, [RH, Score=473, Expect=3e-162]; ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=465, Expect=2e-159]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [Score=369, Expect=2e-122]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=420, Expect=3e-142]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=431, Expect=9e-147]} {RNA1509_15395} {RNA1310_14085} {RNA815_14618}
27. MligTC455_32264 105 2.18 Mlig455_069980

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.625

 1.771 - 0.787 - - - 0.984 Mlig455_069980 {REF} {Length: 2428} {RNA1310_36668} {RNA815_35357}
28. MligTC455_40333 129 2.68 Mlig455_060618

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=2.604

 1.77 - - 0.793 - - 0.977 Mlig455_060618 {REF} {Length: 1071} {RNA1509_15938} {RNA1310_60401} {RNA815_36308}
29. MligTC455_21639 227 4.73 Mlig455_052612

Neo: -

Age: Down-Up-Down

 SLC6A5 1.769 - - - - 0.787 0.982 Mlig455_052612 {REF} {Length: 1918} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=351.9]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=311, Expect=6e-98]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=311, Expect=6e-98]} {Dmel: FBgn0034911, CG5549, [Score=307, Expect=5e-94]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=224, Expect=4e-67]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=271, Expect=6e-84]} {RNA1509_26562} {RNA1310_7302.1} {RNA815_18232}
30. MligTC455_34620 420 8.76 Mlig455_050122

Neo: -

Age: -

 1.76 - - - 0.785 - 0.975 Mlig455_050122 {REF} {Length: 1963} {RNA1509_5703} {RNA1310_29202.1} {RNA815_17789}
31. MligTC455_50029 35 0.74 Mlig455_010619, Mlig455_010708

Neo: -

Age: -

 FOXA1 1.746 - - - 0.950 0.796 -

Mlig455_010619 {REF} {Length: 1170} {Pfam: Forkhead domain [PF00250.20, score=110.8]} {Human: ENSG00000129514, FOXA1, forkhead box A1, [Score=168, Expect=3e-48]; ENSG00000170608, FOXA3, forkhead box A3, [Score=164, Expect=1e-47]; ENSG00000125798, FOXA2, forkhead box A2, [Score=163, Expect=2e-46]} {Mouse: ENSMUSG00000035451, Foxa1, forkhead box A1, [Score=167, Expect=3e-48]; ENSMUSG00000040891, Foxa3, forkhead box A3, [Score=164, Expect=7e-48]; ENSMUSG00000037025, Foxa2, forkhead box A2, [Score=164, Expect=7e-47]} {Dmel: FBgn0000659, fkh, fork head, [Score=169, Expect=2e-48]} {Celegans: WBGene00004013, pha-4, Defective pharyngeal development protein 4, [Score=150, Expect=3e-42]} {Smed: dd_Smed_v6_10718_0_4, dd_Smed_v6_10718_0_4, [Score=175, Expect=2e-51]}

Mlig455_010708 {REF} {Length: 1194} {Pfam: Forkhead domain [PF00250.20, score=110.9]} {Human: ENSG00000129514, FOXA1, forkhead box A1, [Score=168, Expect=3e-48]; ENSG00000125798, FOXA2, forkhead box A2, [Score=163, Expect=2e-46]; ENSG00000170608, FOXA3, forkhead box A3, [Score=163, Expect=1e-47]} {Mouse: ENSMUSG00000035451, Foxa1, forkhead box A1, [Score=167, Expect=4e-48]; ENSMUSG00000040891, Foxa3, forkhead box A3, [Score=165, Expect=2e-48]; ENSMUSG00000037025, Foxa2, forkhead box A2, [Score=164, Expect=9e-47]} {Dmel: FBgn0000659, fkh, fork head, [Score=168, Expect=2e-48]} {Celegans: WBGene00004013, pha-4, Defective pharyngeal development protein 4, [Score=151, Expect=2e-42]} {Smed: dd_Smed_v6_10718_0_3, dd_Smed_v6_10718_0_3, [Score=175, Expect=2e-51]}
32. MligTC455_46163 276 5.75 Mlig455_038039

Neo: -

Age: Down-Up-Up

 MAP3K19 1.745 - 0.773 - - - 0.972 Mlig455_038039 {REF} {Length: 2880} {Pfam: Protein kinase domain [PF00069.27, score=170.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.8]; Ankyrin repeats (3 copies) [PF12796.9, score=87.0]; Ankyrin repeats (many copies) [PF13857.8, score=62.7]; Ankyrin repeats (many copies) [PF13637.8, score=54.2]; Ankyrin repeat [PF13606.8, score=43.2]; Ankyrin repeat [PF00023.32, score=39.4]; Fungal protein kinase [PF17667.3, score=25.5]; ABC1 atypical kinase-like domain [PF03109.18, score=21.0]; Phosphotransferase enzyme family [PF01636.25, score=20.9]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=144, Expect=6e-36]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=147, Expect=2e-37]} {Dmel: FBgn0024329, Mekk1, [Score=124, Expect=5e-29]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=113, Expect=1e-25]} {Smed: dd_Smed_v6_8526_0_8, dd_Smed_v6_8526_0_8, [Score=110, Expect=2e-25]} {RNA1509_28974} {RNA1310_12914, RNA1509_28974} {RNA1509_28974, RNA815_9717}
33. MligTC455_49315 516 10.75 Mlig455_070598

Neo: -

Age: logFC(26M/2M)=-0.322

 SLC24A3 1.736 - - - - 0.772 0.964 Mlig455_070598 {REF} {Length: 3827} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=176.9]} {Human: ENSG00000185052, SLC24A3, solute carrier family 24 member 3, [RH, Score=427, Expect=9e-142]} {Mouse: ENSMUSG00000063873, Slc24a3, solute carrier family 24 (sodium/potassium/calcium exchanger), member 3, [RH, Score=423, Expect=5e-141]} {Dmel: FBgn0037238, CG1090, [Score=384, Expect=2e-125]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [RH, Score=315, Expect=3e-99]} {Smed: dd_Smed_v6_7121_0_1, dd_Smed_v6_7121_0_1, [Score=432, Expect=6e-146]} {RNA1509_8142} {RNA1310_7488, RNA1509_8142} {RNA1509_8142, RNA815_3083.1}
34. MligTC455_02494 237 4.93 Mlig455_004106

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.703/0.00228

 1.734 - - 0.766 - 0.968 - Mlig455_004106 {REF} {Length: 917} {RNA1509_21522, RNA1509_4995} {RNA1310_15694.2, RNA1509_21522} {RNA1509_21522, RNA815_5222}
35. MligTC455_07942 59 1.23 Mlig455_021014

Neo: -

Age: -

 1.734 - - 0.756 - - 0.978 Mlig455_021014 {REF} {Length: 873}
36. MligTC455_19373 162 3.38 Mlig455_040143

Neo: -

Age: -

 CFDP1 1.732 - - 0.751 - - 0.981 Mlig455_040143 {REF} {Length: 2641} {TRANSSPLICED} {Pfam: Bucentaur or craniofacial development [PF07572.14, score=96.6]} {Human: ENSG00000153774, CFDP1, craniofacial development protein 1, [RH, Score=123, Expect=5e-32]} {Mouse: ENSMUSG00000031954, Cfdp1, craniofacial development protein 1, [RH, Score=122, Expect=8e-32]} {Dmel: FBgn0267398, Yeti, [RH, Score=89.7, Expect=1e-20]} {Celegans: WBGene00009565, F39H11.1, [RH, Score=75.1, Expect=1e-15]} {Smed: dd_Smed_v6_2321_0_1, dd_Smed_v6_2321_0_1, [RH, Score=87.8, Expect=2e-20]} {RNA1509_18690, RNA1509_30032, RNA1509_31216} {RNA1310_29020, RNA1509_18690, RNA1509_31216} {RNA1509_18690, RNA1509_31216, RNA815_14432.1}
37. MligTC455_29238 48 1.01 Mlig455_063305

Neo: -

Age: -

 1.717 - - 0.759 0.958 - - Mlig455_063305 {REF} {Length: 892} {TRANSSPLICED} {RNA1310_67367} {RNA815_37220}
38. MligTC455_26817 353 7.36 Mlig455_062943

Neo: -

Age: logFC(26M/2M)=-0.515

 TTLL10 1.709 - - - - 0.744 0.965 Mlig455_062943 {REF} {Length: 3909} {Pfam: Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=21.8]} {Human: ENSG00000162571, TTLL10, tubulin tyrosine ligase like 10, [Score=69.7, Expect=2e-12]} {Mouse: ENSMUSG00000029074, Ttll10, tubulin tyrosine ligase-like family, member 10, [Score=58.2, Expect=8e-09]} {Smed: dd_Smed_v6_9664_0_1, dd_Smed_v6_9664_0_1, [Score=87.4, Expect=9e-19]} {RNA1509_23478} {RNA1310_12709.1} {RNA815_2937}
39. MligTC455_29717 69 1.44 Mlig455_021247

Neo: -

Age: Up-Down-Up

 HELZ2 1.709 - 0.746 - - - 0.963 Mlig455_021247 {REF} {Length: 5204} {Pfam: RNB domain [PF00773.21, score=192.0]; AAA domain [PF13087.8, score=101.1]; AAA domain [PF13086.8, score=42.0]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=21.6]} {Human: ENSG00000130589, HELZ2, helicase with zinc finger 2, [Score=149, Expect=2e-35]} {Mouse: ENSMUSG00000027580, Helz2, helicase with zinc finger 2, transcriptional coactivator, [Score=157, Expect=6e-38]} {Dmel: FBgn0039183, Dis3, [Score=115, Expect=1e-25]} {Celegans: WBGene00018612, disl-2, DIS3-like exonuclease 2, [Score=92.4, Expect=1e-18]} {Smed: dd_Smed_v6_8176_0_1, dd_Smed_v6_8176_0_1, [Score=205, Expect=3e-53]} {RNA1509_30432, RNA1509_5117} {RNA1310_536, RNA1509_30432} {RNA1509_30432, RNA815_182.1}
40. MligTC455_02495 2759 57.47 Mlig455_039292

Neo: -

Age: Down-Up-Up

Region-enriched R2: 3.530/0.00442

 1.705 - - 0.739 - 0.966 - Mlig455_039292 {REF} {Length: 910} {RNA1509_35923, RNA1509_4995, RNA1509_7740} {RNA1310_15694.2, RNA1509_35923, RNA1509_4995, RNA1509_7740} {RNA1509_35923, RNA1509_4995, RNA1509_7740, RNA815_5222}
41. MligTC455_26816 355 7.39 Mlig455_062861

Neo: -

Age: logFC(26M/2M)=-0.333

 TTLL10 1.703 - - - - 0.739 0.964 Mlig455_062861 {REF} {Length: 4729} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=173.8]; YheC/D like ATP-grasp [PF14398.8, score=30.2]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=27.4]; Sugar-transfer associated ATP-grasp [PF14397.8, score=20.6]} {Human: ENSG00000162571, TTLL10, tubulin tyrosine ligase like 10, [RH, Score=323, Expect=5e-100]} {Mouse: ENSMUSG00000029074, Ttll10, tubulin tyrosine ligase-like family, member 10, [RH, Score=319, Expect=2e-98]} {Dmel: FBgn0030823, CG8918, [Score=129, Expect=2e-31]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [Score=99.4, Expect=5e-22]} {Smed: dd_Smed_v6_9664_0_1, dd_Smed_v6_9664_0_1, [RH, Score=445, Expect=2e-147]} {RNA1509_23478, RNA1509_31433, RNA1509_39757} {RNA1310_12709.1, RNA1509_23478, RNA1509_31433, RNA1509_39757} {RNA1509_23478, RNA1509_31433, RNA1509_39757, RNA815_2937}
42. MligTC455_16328 280 5.84 Mlig455_045453

Neo: -

Age: -

 1.701 - - - 0.748 - 0.953 Mlig455_045453 {REF} {Length: 3160} {TRANSSPLICED} {RNA1509_37962} {RNA1310_20237.1} {RNA815_18052}
43. MligTC455_40801 425 8.85 Mlig455_003100, Mlig455_062789

Neo: -

Age: logFC(26M/2M)=-0.250

Region-enriched R2: 3.506/0.00053
Region-enriched R3: 2.405/0.00633

 MDH1B 1.701 - - - - 0.726 0.975

Mlig455_003100 {REF} {Length: 4802} {Pfam: lactate/malate dehydrogenase, alpha/beta C-terminal domain [PF02866.20, score=53.0]} {Human: ENSG00000138400, MDH1B, malate dehydrogenase 1B, [Score=323, Expect=1e-102]} {Mouse: ENSMUSG00000025963, Mdh1b, malate dehydrogenase 1B, NAD (soluble), [Score=304, Expect=1e-95]} {Dmel: FBgn0262782, Mdh1, Malate dehydrogenase 1, [Score=107, Expect=3e-25]} {Celegans: WBGene00018491, mdh-1, Malate DeHydrogenase, [Score=98.2, Expect=4e-22]} {Smed: dd_Smed_v6_10200_0_1, dd_Smed_v6_10200_0_1, [Score=335, Expect=2e-106]} {RNA1509_47623, RNA1509_9622} {RNA1310_5189, RNA1509_47623} {RNA1509_47623, RNA815_3770}

Mlig455_062789 {REF} {Length: 2979} {Pfam: lactate/malate dehydrogenase, alpha/beta C-terminal domain [PF02866.20, score=52.9]} {Human: ENSG00000138400, MDH1B, malate dehydrogenase 1B, [Score=323, Expect=1e-102]} {Mouse: ENSMUSG00000025963, Mdh1b, malate dehydrogenase 1B, NAD (soluble), [Score=304, Expect=1e-95]} {Dmel: FBgn0262782, Mdh1, Malate dehydrogenase 1, [Score=105, Expect=2e-24]} {Celegans: WBGene00018491, mdh-1, Malate DeHydrogenase, [Score=97.8, Expect=5e-22]} {Smed: dd_Smed_v6_10200_0_1, dd_Smed_v6_10200_0_1, [RH, Score=337, Expect=1e-107]} {RNA1509_9622} {RNA1310_5189, RNA1509_9622} {RNA1509_9622, RNA815_3770}
44. MligTC455_49211 30 0.63 Mlig455_044533

Neo: -

Age: -

 1.698 - - - 0.732 0.966 - Mlig455_044533 {REF} {Length: 2489} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=139.7]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=62.0, Expect=5e-10]} {Smed: dd_Smed_v6_26469_0_1, dd_Smed_v6_26469_0_1, [Score=51.6, Expect=1e-07]} {RNA1509_50956} {RNA1310_27155} {RNA815_39321}
45. MligTC455_06678 10 0.22 Mlig455_051040

Neo: -

Age: -

 SLC7A1 1.694 - - - 0.706 0.988 - Mlig455_051040 {REF} {Length: 1969} {Pfam: Amino acid permease [PF13520.8, score=122.2]; Amino acid permease [PF00324.23, score=107.8]; C-terminus of AA_permease [PF13906.8, score=56.1]} {Human: ENSG00000139514, SLC7A1, solute carrier family 7 member 1, [Score=297, Expect=3e-92]} {Mouse: ENSMUSG00000041313, Slc7a1, solute carrier family 7 (cationic amino acid transporter, y+ system), member 1, [Score=300, Expect=2e-93]; ENSMUSG00000022756, Slc7a4, solute carrier family 7 (cationic amino acid transporter, y+ system), member 4, [Score=297, Expect=3e-92]; ENSMUSG00000054753, AU018091, expressed sequence AU018091, [Score=290, Expect=5e-89]; ENSMUSG00000107871, AU018091, expressed sequence AU018091, [Score=290, Expect=5e-89]} {Dmel: FBgn0036984, CG13248, [Score=290, Expect=1e-89]} {Celegans: WBGene00016806, C50D2.2, [Score=293, Expect=1e-91]} {Smed: dd_Smed_v6_8652_0_4, dd_Smed_v6_8652_0_4, [Score=436, Expect=3e-147]} {RNA1310_82370} {RNA815_51664}
46. MligTC455_39264 466 9.71 Mlig455_025156, Mlig455_063918

Neo: -

Age: Down-Up-Down

 ZAN 1.694 - 0.703 - - - 0.991

Mlig455_025156 {REF} {Length: 4121} {RNA1509_26470, RNA1509_50938} {RNA1310_7875, RNA1509_26470} {RNA1509_26470, RNA815_14212}

Mlig455_063918 {REF} {Length: 3617} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=98.6, Expect=3e-20]} {Mouse: ENSMUSG00000000037, Scml2, Scm polycomb group protein like 2, [Score=68.2, Expect=3e-11]} {RNA1509_50938} {RNA1310_7875} {RNA815_14212}
47. MligTC455_23331 165 3.43 Mlig455_016108, Mlig455_036912

Neo: -

Age: -

 1.69 - - - 0.719 - 0.971

Mlig455_016108 {REF} {Length: 1041} {NoTransDecoderORF} {RNA1509_24217} {RNA1310_48796} {RNA815_25805}

Mlig455_036912 {REF} {Length: 669} {NoTransDecoderORF} {RNA1509_24217} {RNA1310_48796} {RNA815_25805}
48. MligTC455_29718 108 2.25 Mlig455_021509

Neo: -

Age: -

 HELZ2 1.69 - 0.726 - - - 0.964 Mlig455_021509 {REF} {Length: 8247} {Pfam: RNB domain [PF00773.21, score=194.3]; AAA domain [PF13086.8, score=135.4]; AAA domain [PF13087.8, score=127.8]; AAA domain [PF13604.8, score=32.3]; AAA domain [PF13245.8, score=23.3]; Dis3-like cold-shock domain 2 (CSD2) [PF17849.3, score=21.1]; Type II/IV secretion system protein [PF00437.22, score=18.1]} {Human: ENSG00000130589, HELZ2, helicase with zinc finger 2, [Score=211, Expect=4e-54]} {Mouse: ENSMUSG00000027580, Helz2, helicase with zinc finger 2, transcriptional coactivator, [Score=281, Expect=1e-75]} {Dmel: FBgn0039183, Dis3, [Score=126, Expect=1e-28]} {Celegans: WBGene00004880, smg-2, Regulator of nonsense transcripts 1, [Score=101, Expect=3e-21]} {Smed: dd_Smed_v6_7048_0_2, dd_Smed_v6_7048_0_2, [Score=284, Expect=5e-77]} {RNA1509_22882, RNA1509_5117, RNA1509_8567} {RNA1310_536, RNA1509_22882, RNA1509_8567} {RNA1509_22882, RNA1509_8567, RNA815_182.1}
49. MligTC455_15765 194 4.05 Mlig455_007606

Neo: -

Age: -

 1.678 - - 0.721 - - 0.957 Mlig455_007606 {REF} {Length: 1349} {RNA1310_25770.1} {RNA815_11095}
50. MligTC455_15081 19 0.39 Mlig455_065134

Neo: -

Age: -

 0.996 - - - - 0.996 - Mlig455_065134 {REF} {Length: 1297} {RNA1310_74150}
51. MligTC455_38922 1324 27.57 Mlig455_055899

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.333

 MX2 0.991 - - - - - 0.991 Mlig455_055899 {REF} {Length: 3320} {Pfam: Dynamin central region [PF01031.22, score=177.8]; Dynamin family [PF00350.25, score=125.7]; Dynamin GTPase effector domain [PF02212.20, score=46.3]; 50S ribosome-binding GTPase [PF01926.25, score=21.2]; AAA ATPase domain [PF13191.8, score=19.7]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=1e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=308, Expect=3e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=182, Expect=9e-48]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=176, Expect=6e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=198, Expect=2e-53]} {RNA1509_37170, RNA1509_6400} {RNA1310_6542.1, RNA1509_37170, RNA1509_6400} {RNA1509_37170, RNA1509_6400, RNA815_1426.1}
52. MligTC455_19097 120 2.49 Mlig455_035179

Neo: -

Age: -

Region-enriched R2: 5.873/0.00339
Region-enriched R3: 5.589/0.00004

 KCNK3 0.99 - - - - - 0.990 Mlig455_035179 {REF} {Length: 2899} {Pfam: Ion channel [PF07885.18, score=103.1]; Ion transport protein [PF00520.33, score=23.8]} {Human: ENSG00000171303, KCNK3, potassium two pore domain channel subfamily K member 3, [Score=67.0, Expect=5e-11]; ENSG00000169427, KCNK9, potassium two pore domain channel subfamily K member 9, [Score=65.9, Expect=1e-10]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=72.4, Expect=6e-13]} {Dmel: FBgn0033257, sand, sandman, [Score=105, Expect=4e-24]} {Celegans: WBGene00006690, twk-39, TWiK family of potassium channels, [RH, Score=117, Expect=4e-27]} {Smed: dd_Smed_v6_21895_0_1, dd_Smed_v6_21895_0_1, [RH, Score=188, Expect=7e-51]} {RNA1310_31604} {RNA815_54785}
53. MligTC455_09773 633 13.18 Mlig455_031595

Neo: -

Age: -

 0.987 - - - - - 0.987 Mlig455_031595 {REF} {Length: 1992} {RNA1509_30983} {RNA1310_27418, RNA1509_30983} {RNA1509_30983, RNA815_40613}
54. MligTC455_37811 192 3.99 Mlig455_010190, Mlig455_058688

Neo: -

Age: Down-Up-Down

 0.987 - - - - - 0.987

Mlig455_010190 {REF} {Length: 2948} {Smed: dd_Smed_v6_62611_0_1, dd_Smed_v6_62611_0_1, [RH, Score=71.6, Expect=3e-15]} {RNA1509_46223} {RNA1310_14882} {RNA815_30586}

Mlig455_058688 {REF} {Length: 3085} {Smed: dd_Smed_v6_62611_0_1, dd_Smed_v6_62611_0_1, [RH, Score=71.6, Expect=3e-15]} {RNA1509_46223} {RNA1310_14882} {RNA815_30586}
55. MligTC455_46561 132 2.75 Mlig455_031728

Neo: -

Age: logFC(26M/2M)=-0.387

 0.987 - - - - - 0.987 Mlig455_031728 {REF} {Length: 2506} {RNA1509_39227} {RNA1310_10162.2} {RNA815_11026}
56. MligTC455_03723 113 2.36 Mlig455_021604

Neo: -

Age: -

 POU6F2 0.986 - - - - - 0.986 Mlig455_021604 {REF} {Length: 3537} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=101.1]; Uncharacterized conserved domain (SAYSvFN) [PF10260.11, score=75.9]; Homeodomain [PF00046.31, score=59.3]} {Human: ENSG00000106536, POU6F2, POU class 6 homeobox 2, [RH, Score=247, Expect=1e-71]} {Mouse: ENSMUSG00000009734, Pou6f2, POU domain, class 6, transcription factor 2, [RH, Score=247, Expect=3e-72]} {Dmel: FBgn0261588, pdm3, pou domain motif 3, [RH, Score=243, Expect=2e-67]} {Celegans: WBGene00000441, ceh-18, Homeobox protein ceh-18, [Score=123, Expect=2e-29]} {Smed: dd_Smed_v6_13010_0_1, dd_Smed_v6_13010_0_1, [RH, Score=231, Expect=2e-67]} {RNA1509_23034, RNA1509_27833, RNA1509_54528} {RNA1310_7430, RNA1509_27833, RNA1509_54528} {RNA1509_27833, RNA1509_54528, RNA815_11647}
57. MligTC455_18522 455 9.47 Mlig455_008847, Mlig455_008948

Neo: -

Age: logFC(26M/2M)=-0.379

 RASEF 0.986 - - - - - 0.986

Mlig455_008847 {REF} {Length: 4934} {Pfam: Ras family [PF00071.24, score=159.8]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=100.2]; ADP-ribosylation factor family [PF00025.23, score=54.0]; EF-hand domain [PF13405.8, score=28.8]; EF-hand domain pair [PF13499.8, score=28.3]; 50S ribosome-binding GTPase [PF01926.25, score=26.0]} {Human: ENSG00000165105, RASEF, RAS and EF-hand domain containing, [Score=238, Expect=7e-67]} {Mouse: ENSMUSG00000043003, Rasef, RAS and EF hand domain containing, [RH, Score=259, Expect=4e-75]} {Dmel: FBgn0285937, Rab1, [Score=134, Expect=9e-36]} {Celegans: WBGene00016344, rsef-1, Ras and EF-hand domain-containing protein homolog, [Score=177, Expect=1e-46]} {Smed: dd_Smed_v6_12567_0_1, dd_Smed_v6_12567_0_1, [RH, Score=189, Expect=7e-51]} {RNA1310_9926} {RNA815_2505}

Mlig455_008948 {REF} {Length: 4701} {Pfam: Ras family [PF00071.24, score=159.8]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=100.2]; ADP-ribosylation factor family [PF00025.23, score=54.0]; EF-hand domain [PF13405.8, score=31.0]; EF-hand domain pair [PF13499.8, score=28.9]; 50S ribosome-binding GTPase [PF01926.25, score=25.9]; EF hand [PF00036.34, score=20.0]; EF hand [PF13202.8, score=19.4]} {Human: ENSG00000165105, RASEF, RAS and EF-hand domain containing, [Score=184, Expect=2e-48]} {Mouse: ENSMUSG00000043003, Rasef, RAS and EF hand domain containing, [RH, Score=261, Expect=7e-76]} {Dmel: FBgn0285937, Rab1, [Score=134, Expect=1e-35]} {Celegans: WBGene00016344, rsef-1, Ras and EF-hand domain-containing protein homolog, [Score=177, Expect=1e-46]} {Smed: dd_Smed_v6_12567_0_1, dd_Smed_v6_12567_0_1, [RH, Score=189, Expect=3e-51]} {RNA1310_9926} {RNA815_2505}
58. MligTC455_33138 411 8.55 Mlig455_066388

Neo: -

Age: Down-Up-Down

 0.986 - - - - - 0.986 Mlig455_066388 {REF} {Length: 2423} {RNA1509_29764} {RNA1310_1953.1} {RNA815_1322}
59. MligTC455_39265 459 9.57 Mlig455_025157, Mlig455_063935

Neo: -

Age: Down-Up-Down

 PRX 0.986 - - - - - 0.986

Mlig455_025157 {REF} {Length: 1721} {RNA1509_50938} {RNA1310_45103} {RNA815_28196.1}

Mlig455_063935 {REF} {Length: 4827} {Human: ENSG00000105227, PRX, periaxin, [Score=66.6, Expect=3e-10]} {RNA1509_50938} {RNA1310_7875} {RNA815_14212}
60. MligTC455_52032 733 15.27 Mlig455_049281, Mlig455_049292

Neo: -

Age: -

Region-enriched R2: 1.871/0.03166

 PPIL6 0.986 - - - - - 0.986

Mlig455_049281 {REF} {Length: 1491} {TRANSSPLICED} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=138.3]} {Human: ENSG00000185250, PPIL6, peptidylprolyl isomerase like 6, [RH, Score=278, Expect=2e-92]} {Mouse: ENSMUSG00000078451, Ppil6, peptidylprolyl isomerase (cyclophilin)-like 6, [RH, Score=267, Expect=2e-88]} {Dmel: FBgn0036415, CG7768, [Score=153, Expect=7e-46]} {Celegans: WBGene00000883, cyn-7, Peptidyl-prolyl cis-trans isomerase 7, [Score=174, Expect=4e-54]} {Smed: dd_Smed_v6_10327_0_1, dd_Smed_v6_10327_0_1, [RH, Score=200, Expect=1e-64]} {RNA1509_38880, RNA1509_54777, RNA1509_5736} {RNA1310_29201, RNA1509_38880, RNA1509_54777} {RNA1509_38880, RNA1509_54777, RNA815_16054}

Mlig455_049292 {REF} {Length: 1337} {TRANSSPLICED} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=143.4]} {Human: ENSG00000185250, PPIL6, peptidylprolyl isomerase like 6, [RH, Score=256, Expect=1e-84]} {Mouse: ENSMUSG00000078451, Ppil6, peptidylprolyl isomerase (cyclophilin)-like 6, [Score=253, Expect=5e-83]} {Dmel: FBgn0036415, CG7768, [Score=159, Expect=1e-48]} {Celegans: WBGene00000883, cyn-7, Peptidyl-prolyl cis-trans isomerase 7, [Score=179, Expect=2e-56]} {Smed: dd_Smed_v6_10327_0_1, dd_Smed_v6_10327_0_1, [RH, Score=203, Expect=3e-66]} {RNA1509_5736} {RNA1310_29201, RNA1509_5736} {RNA1509_5736, RNA815_16054}
61. MligTC455_10456 173 3.6 Mlig455_036936

Neo: -

Age: Down-Up-Down

 0.985 - - - - - 0.985 Mlig455_036936 {REF} {Length: 2942} {RNA1509_52192} {RNA1310_9569.2, RNA1509_52192} {RNA1509_52192, RNA815_10835}
62. MligTC455_23287 106 2.21 Mlig455_052789

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.273/0.00029

 0.985 - - - - - 0.985 Mlig455_052789 {REF} {Length: 2348} {RNA1310_41474} {RNA815_41242}
63. MligTC455_26313 169 3.51 Mlig455_056974

Neo: -

Age: -

 ENDOV 0.985 - - - - - 0.985 Mlig455_056974 {REF} {Length: 4726} {TRANSSPLICED} {Pfam: Endonuclease V [PF04493.16, score=198.3]} {Human: ENSG00000173818, ENDOV, endonuclease V, [Score=200, Expect=9e-64]} {Mouse: ENSMUSG00000039850, Endov, endonuclease V, [Score=206, Expect=2e-65]} {Celegans: WBGene00007464, C08H9.3, Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase, [Score=94.0, Expect=4e-22]} {Smed: dd_Smed_v6_9595_0_3, dd_Smed_v6_9595_0_3, [Score=107, Expect=3e-28]} {RNA1509_46904} {RNA1310_33222, RNA1509_46904} {RNA1509_46904, RNA815_14313.1}
64. MligTC455_36187 339 7.06 Mlig455_036148

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.329

 KCNH7 0.985 - - - - - 0.985 Mlig455_036148 {REF} {Length: 4967} {Pfam: Ion transport protein [PF00520.33, score=125.0]; Cyclic nucleotide-binding domain [PF00027.31, score=50.6]; PAS domain [PF13426.9, score=47.2]; Ion channel [PF07885.18, score=46.1]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=25.4]; PAS fold [PF00989.27, score=24.3]; PAS fold [PF08447.14, score=24.1]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [RH, Score=851, Expect=0.0]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [RH, Score=824, Expect=0.0]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [RH, Score=821, Expect=0.0]} {Mouse: ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [RH, Score=960, Expect=0.0]} {Dmel: FBgn0003353, sei, seizure, [RH, Score=772, Expect=0.0]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [RH, Score=759, Expect=0.0]} {Smed: dd_Smed_v6_12621_0_1, dd_Smed_v6_12621_0_1, [RH, Score=878, Expect=0.0]} {RNA1509_16542} {RNA1310_9991} {RNA815_4089.1}
65. MligTC455_36865 76 1.58 Mlig455_035893

Neo: -

Age: -

 0.985 - - - - - 0.985 Mlig455_035893 {REF} {Length: 249} {NoTransDecoderORF} {RNA1509_23064} {RNA1310_87686}
66. MligTC455_46751 428 8.91 Mlig455_071077

Neo: -

Age: -

Region-enriched R6: 1.655/0.00681

 FAXC 0.985 - - - - - 0.985 Mlig455_071077 {REF} {Length: 1373} {Pfam: Glutathione S-transferase N-terminal domain [PF17172.6, score=83.0]; Glutathione S-transferase, C-terminal domain [PF17171.6, score=47.2]; Outer mitochondrial membrane transport complex protein [PF10568.11, score=22.4]; Glutathione S-transferase, C-terminal domain [PF13410.8, score=20.0]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=19.6]} {Human: ENSG00000146267, FAXC, failed axon connections homolog, [Score=94.7, Expect=3e-22]} {Mouse: ENSMUSG00000028246, Faxc, failed axon connections homolog, [Score=95.1, Expect=1e-22]} {Dmel: FBgn0014163, fax, failed axon connections, [Score=139, Expect=3e-39]} {Celegans: WBGene00012987, Y48C3A.3, [Score=144, Expect=8e-42]} {Smed: dd_Smed_v6_1736_0_1, dd_Smed_v6_1736_0_1, [Score=177, Expect=2e-55]} {RNA1509_35639} {RNA1310_2517.2} {RNA815_2965}
67. MligTC455_50075 291 6.07 Mlig455_042192, Mlig455_059013

Neo: -

Age: -

 0.985 - - - - - 0.985

Mlig455_042192 {REF} {Length: 3775} {RNA1509_21332, RNA1509_22951} {RNA1310_3394, RNA1509_22951} {RNA1509_22951, RNA815_2506.1}

Mlig455_059013 {REF} {Length: 3781} {RNA1509_21332} {RNA1310_3394, RNA1509_21332} {RNA1509_21332, RNA815_2506.1}
68. MligTC455_11936 211 4.39 Mlig455_030280

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.982

 SGK494 0.984 - - - - - 0.984 Mlig455_030280 {REF} {Length: 3532} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=180.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=87.8]; Phosphotransferase enzyme family [PF01636.25, score=21.2]; Kinase-like [PF14531.8, score=19.6]} {Human: ENSG00000167524, SGK494, uncharacterized serine/threonine-protein kinase SgK494, [RH, Score=207, Expect=2e-61]} {Mouse: ENSMUSG00000097721, Rps6kb2, ribosomal protein S6 kinase, polypeptide 2, [Score=173, Expect=5e-48]; ENSMUSG00000024830, Rps6kb2, ribosomal protein S6 kinase, polypeptide 2, [Score=173, Expect=5e-48]; ENSMUSG00000020516, Rps6kb1, ribosomal protein S6 kinase, polypeptide 1, [Score=172, Expect=4e-47]; ENSMUSG00000029053, Prkcz, protein kinase C, zeta, [Score=167, Expect=2e-46]} {Dmel: FBgn0283473, S6KL, S6 Kinase Like, [RH, Score=195, Expect=3e-56]} {Celegans: WBGene00017950, F31E3.2, Putative serine/threonine-protein kinase F31E3.2, [RH, Score=202, Expect=1e-59]} {Smed: dd_Smed_v6_7868_0_1, dd_Smed_v6_7868_0_1, [RH, Score=292, Expect=2e-92]} {RNA1509_34459} {RNA1310_14015.2} {RNA815_17648}
69. MligTC455_18592 298 6.21 Mlig455_010926, Mlig455_033158

Neo: -

Age: Down-Down-Up

Region-enriched R2: 4.164/0.00576

 0.984 - - - - - 0.984

Mlig455_010926 {REF} {Length: 2976} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=62.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=22.7]} {RNA1310_17147} {RNA815_22741}

Mlig455_033158 {REF} {Length: 2437} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=61.0]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=22.6]} {RNA1310_17147} {RNA815_22741}
70. MligTC455_22743 237 4.94 Mlig455_010647, Mlig455_010652, Mlig455_010750

Neo: -

Age: -

 ERBIN 0.984 - - - - - 0.984

Mlig455_010647 {REF} {Length: 596} {Pfam: Leucine rich repeat [PF13855.8, score=40.8]; Leucine Rich repeats (2 copies) [PF12799.9, score=30.4]; Leucine-rich repeat [PF14580.8, score=18.5]} {RNA1509_53260} {RNA1310_7797} {RNA815_12315}

Mlig455_010652 {REF} {Length: 2595} {TRANSSPLICED} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=99.9]; Leucine rich repeat [PF13855.8, score=69.7]; Leucine-rich repeat [PF14580.8, score=24.2]; Leucine Rich repeat [PF13516.8, score=21.7]} {Human: ENSG00000112851, ERBIN, erbb2 interacting protein, [Score=77.0, Expect=2e-14]; ENSG00000139263, LRIG3, leucine rich repeats and immunoglobulin like domains 3, [Score=73.2, Expect=5e-13]} {Mouse: ENSMUSG00000040367, Lrrd1, leucine rich repeats and death domain containing 1, [Score=87.8, Expect=7e-18]} {Dmel: FBgn0263289, scrib, scribbled, [Score=75.5, Expect=5e-14]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=69.3, Expect=3e-12]} {Smed: dd_Smed_v6_5405_0_1, dd_Smed_v6_5405_0_1, [Score=71.2, Expect=1e-13]} {RNA1509_34182, RNA1509_53260} {RNA1310_7797, RNA1509_34182, RNA1509_53260} {RNA1509_34182, RNA1509_53260, RNA815_12315}

Mlig455_010750 {REF} {Length: 2613} {TRANSSPLICED} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=99.0]; Leucine rich repeat [PF13855.8, score=69.5]; Leucine Rich repeat [PF13516.8, score=20.6]; Leucine-rich repeat [PF14580.8, score=19.8]} {Human: ENSG00000112851, ERBIN, erbb2 interacting protein, [Score=76.6, Expect=6e-14]; ENSG00000139263, LRIG3, leucine rich repeats and immunoglobulin like domains 3, [Score=72.8, Expect=9e-13]} {Mouse: ENSMUSG00000040367, Lrrd1, leucine rich repeats and death domain containing 1, [Score=87.8, Expect=1e-17]} {Dmel: FBgn0263289, scrib, scribbled, [Score=74.7, Expect=1e-13]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=68.6, Expect=7e-12]} {Smed: dd_Smed_v6_5405_0_1, dd_Smed_v6_5405_0_1, [Score=70.9, Expect=2e-13]} {RNA1509_53260} {RNA1310_7797} {RNA815_12315}
71. MligTC455_24481 79 1.65 Mlig455_003858

Neo: -

Age: Down-Up-Down

 0.984 - - - - - 0.984 Mlig455_003858 {REF} {Length: 5919} {NoTransDecoderORF} {RNA1509_26670} {RNA1310_9883} {RNA815_20555}
72. MligTC455_24482 93 1.94 Mlig455_003650

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.449

 0.984 - - - - - 0.984 Mlig455_003650 {REF} {Length: 5923} {RNA1509_28809, RNA1509_43110, RNA1509_57952} {RNA1310_1274.1, RNA1509_28809, RNA1509_43110, RNA1509_57952} {RNA1509_28809, RNA1509_43110, RNA1509_57952, RNA815_5270}
73. MligTC455_27799 414 8.62 Mlig455_004285, Mlig455_004370

Neo: -

Age: Down-Up-Down

Region-specific R2: 3.850

Region-enriched R2: 5.047/0.00000

 0.984 - - - - - 0.984

Mlig455_004285 {REF} {Length: 650} {RNA1509_56105} {RNA1310_32410} {RNA815_17871.1}

Mlig455_004370 {REF} {Length: 1653} {RNA1509_56105} {RNA1310_32410} {RNA815_17871.1}
74. MligTC455_36910 84 1.75 Mlig455_031683

Neo: -

Age: -

 0.984 - - - - - 0.984 Mlig455_031683 {REF} {Length: 4716} {RNA1509_36080} {RNA1310_44068, RNA1509_36080} {RNA1509_36080, RNA815_39601}
75. MligTC455_42485 159 3.31 Mlig455_046457

Neo: -

Age: -

 0.984 - - - - - 0.984 Mlig455_046457 {REF} {Length: 846} {RNA1310_40237.1} {RNA815_18246}
76. MligTC455_50649 91 1.9 Mlig455_014003

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.708

 GRM3 0.984 - - - - - 0.984 Mlig455_014003 {REF} {Length: 4598} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=148.4]; Receptor family ligand binding region [PF01094.30, score=25.5]; Nine Cysteines Domain of family 3 GPCR [PF07562.16, score=23.6]} {Human: ENSG00000198822, GRM3, glutamate metabotropic receptor 3, [Score=243, Expect=1e-68]; ENSG00000196277, GRM7, glutamate metabotropic receptor 7, [Score=235, Expect=1e-65]; ENSG00000164082, GRM2, glutamate metabotropic receptor 2, [Score=233, Expect=3e-65]; ENSG00000179603, GRM8, glutamate metabotropic receptor 8, [Score=231, Expect=2e-64]} {Mouse: ENSMUSG00000003974, Grm3, glutamate receptor, metabotropic 3, [Score=240, Expect=7e-68]; ENSMUSG00000023192, Grm2, glutamate receptor, metabotropic 2, [Score=237, Expect=1e-66]; ENSMUSG00000024211, Grm8, glutamate receptor, metabotropic 8, [Score=236, Expect=3e-66]; ENSMUSG00000056755, Grm7, glutamate receptor, metabotropic 7, [Score=234, Expect=9e-66]} {Dmel: FBgn0050361, mtt, mangetout, [Score=273, Expect=2e-80]} {Celegans: WBGene00003232, mgl-1, Probable metabotropic glutamate receptor mgl-1, [Score=213, Expect=1e-58]} {Smed: dd_Smed_v6_10130_0_1, dd_Smed_v6_10130_0_1, [Score=290, Expect=1e-85]} {RNA1509_34817} {RNA1310_58007} {RNA815_44956}
77. MligTC455_51083 1601 33.34 Mlig455_008002

Neo: -

Age: -

 SMIM7 0.984 - - - - - 0.984 Mlig455_008002 {REF} {Length: 592} {TRANSSPLICED} {Pfam: Yos1-like [PF08571.12, score=20.1]} {Human: ENSG00000214046, SMIM7, small integral membrane protein 7, [RH, Score=77.4, Expect=3e-20]; ENSG00000268790, AC008764.4, novel protein, [RH, Score=73.6, Expect=8e-19]} {Mouse: ENSMUSG00000044600, Smim7, small integral membrane protein 7, [RH, Score=79.3, Expect=4e-21]} {Celegans: WBGene00021784, cogc-4, Conserved oligomeric Golgi complex subunit 4, [RH, Score=79.7, Expect=1e-21]} {RNA1509_17989} {RNA1310_43671.1} {RNA815_20598.1}
78. MligTC455_52255 215 4.48 Mlig455_020595

Neo: -

Age: -

 0.984 - - - - - 0.984 Mlig455_020595 {REF} {Length: 2601} {Pfam: TIR domain [PF13676.8, score=69.5]; BTK motif [PF00779.21, score=29.8]; TIR domain [PF01582.22, score=24.8]} {Smed: dd_Smed_v6_4452_0_1, dd_Smed_v6_4452_0_1, [Score=70.9, Expect=1e-12]} {RNA1509_54137} {RNA1310_8917.1} {RNA815_7724}
79. MligTC455_09172 71 1.49 Mlig455_002936

Neo: -

Age: -

 0.983 - - - - - 0.983 Mlig455_002936 {REF} {Length: 1026} {NoTransDecoderORF} {RNA1310_55646}
80. MligTC455_11148 110 2.29 Mlig455_015359

Neo: -

Age: -

 C11orf65 0.983 - - - - - 0.983 Mlig455_015359 {REF} {Length: 2596} {TRANSSPLICED} {Pfam: BNIP3 [PF06553.14, score=27.4]; Restriction endonuclease FokI, recognition domain [PF02981.17, score=20.9]; IQ calmodulin-binding motif [PF00612.29, score=19.1]} {Human: ENSG00000166323, C11orf65, chromosome 11 open reading frame 65, [RH, Score=224, Expect=1e-67]} {Mouse: ENSMUSG00000005131, 4930550C14Rik, RIKEN cDNA 4930550C14 gene, [RH, Score=210, Expect=3e-62]} {Smed: dd_Smed_v6_13591_0_1, dd_Smed_v6_13591_0_1, [RH, Score=236, Expect=2e-72]} {RNA1310_22540.2} {RNA815_13464}
81. MligTC455_20984 353 7.35 Mlig455_000521

Neo: -

Age: logFC(26M/2M)=-0.604

 0.983 - - - - - 0.983 Mlig455_000521 {REF} {Length: 872} {TRANSSPLICED} {RNA1509_58488} {RNA1310_36320, RNA1509_58488} {RNA1509_58488, RNA815_19506}
82. MligTC455_23081 239 4.97 Mlig455_070003

Neo: -

Age: logFC(26M/2M)=-0.477

 LRP1B 0.983 - - - - - 0.983 Mlig455_070003 {REF} {Length: 1873} {Pfam: EGF-like domain [PF00008.29, score=35.2]; EGF-like domain [PF07974.15, score=19.2]} {Human: ENSG00000168702, LRP1B, LDL receptor related protein 1B, [Score=58.9, Expect=2e-09]} {Mouse: ENSMUSG00000049252, Lrp1b, low density lipoprotein-related protein 1B (deleted in tumors), [Score=53.9, Expect=7e-08]; ENSMUSG00000027878, Notch2, notch 2, [Score=53.5, Expect=1e-07]; ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=53.1, Expect=1e-07]} {Dmel: FBgn0004647, N, Notch, [Score=47.8, Expect=5e-06]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=54.3, Expect=3e-08]} {RNA1509_38266} {RNA1310_19274, RNA1509_38266} {RNA1509_38266, RNA815_9585.2}
83. MligTC455_26487 338 7.05 Mlig455_063885

Neo: -

Age: -

Region-enriched R5: 2.302/0.02522

 CCDC88C 0.983 - - - - - 0.983 Mlig455_063885 {REF} {Length: 5084} {TRANSSPLICED} {Human: ENSG00000015133, CCDC88C, coiled-coil domain containing 88C, [Score=102, Expect=3e-21]; ENSG00000115355, CCDC88A, coiled-coil domain containing 88A, [Score=100, Expect=1e-20]} {Mouse: ENSMUSG00000032740, Ccdc88a, coiled coil domain containing 88A, [Score=94.4, Expect=8e-19]; ENSMUSG00000021182, Ccdc88c, coiled-coil domain containing 88C, [Score=94.0, Expect=1e-18]} {Dmel: FBgn0283724, Girdin, [Score=91.3, Expect=5e-18]} {Celegans: WBGene00013082, grdn-1, Girdin homolog, [Score=55.8, Expect=2e-07]} {Smed: dd_Smed_v6_5291_0_2, dd_Smed_v6_5291_0_2, [Score=144, Expect=1e-34]} {RNA1509_18704} {RNA1310_2232.1, RNA1509_18704} {RNA1509_18704, RNA815_6605}
84. MligTC455_28625 581 12.11 Mlig455_054053

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.214

 RPS6KA2 0.983 - - - - - 0.983 Mlig455_054053 {REF} {Length: 5140} {Pfam: Protein kinase domain [PF00069.27, score=460.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=251.5]; ABC1 atypical kinase-like domain [PF03109.18, score=45.4]; Kinase-like [PF14531.8, score=38.0]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=34.0]; Phosphotransferase enzyme family [PF01636.25, score=27.5]; Fungal protein kinase [PF17667.3, score=25.9]; Protein kinase C terminal domain [PF00433.26, score=23.0]} {Human: ENSG00000071242, RPS6KA2, ribosomal protein S6 kinase A2, [RH, Score=955, Expect=0.0]; ENSG00000177189, RPS6KA3, ribosomal protein S6 kinase A3, [RH, Score=954, Expect=0.0]; ENSG00000281877, RPS6KA1, ribosomal protein S6 kinase A1, [RH, Score=952, Expect=0.0]; ENSG00000117676, RPS6KA1, ribosomal protein S6 kinase A1, [RH, Score=952, Expect=0.0]} {Mouse: ENSMUSG00000031309, Rps6ka3, ribosomal protein S6 kinase polypeptide 3, [RH, Score=956, Expect=0.0]; ENSMUSG00000003644, Rps6ka1, ribosomal protein S6 kinase polypeptide 1, [RH, Score=954, Expect=0.0]; ENSMUSG00000023809, Rps6ka2, ribosomal protein S6 kinase, polypeptide 2, [RH, Score=951, Expect=0.0]} {Dmel: FBgn0262866, S6kII, Ribosomal protein S6 kinase II, [RH, Score=837, Expect=0.0]} {Celegans: WBGene00011352, rskn-1, Putative ribosomal protein S6 kinase alpha-1, [RH, Score=823, Expect=0.0]} {Smed: dd_Smed_v6_6365_0_1, dd_Smed_v6_6365_0_1, [RH, Score=944, Expect=0.0]} {RNA1509_12001, RNA1509_14082, RNA1509_1755, RNA1509_23210, RNA1509_25306, RNA1509_38436, RNA1509_50737} {RNA1310_2220.1, RNA1509_12001, RNA1509_14082, RNA1509_23210, RNA1509_25306, RNA1509_38436, RNA1509_50737} {RNA1509_12001, RNA1509_14082, RNA1509_23210, RNA1509_25306, RNA1509_38436, RNA1509_50737, RNA815_703.1}
85. MligTC455_31026 213 4.44 Mlig455_070678

Neo: -

Age: -

 0.983 - - - - - 0.983 Mlig455_070678 {REF} {Length: 2471} {TRANSSPLICED} {RNA1509_24158} {RNA1310_3578.2} {RNA815_12643}
86. MligTC455_33283 354 7.37 Mlig455_051062

Neo: Irradiation

Age: -

Region-enriched R2: 3.094/0.03650

 0.983 - - - - - 0.983 Mlig455_051062 {REF} {Length: 2962} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=21.6]} {Mouse: ENSMUSG00000031620, Iqcm, IQ motif containing M, [RH, Score=117, Expect=3e-28]} {RNA1509_32167} {RNA1310_961} {RNA815_7534}
87. MligTC455_33876 123 2.56 Mlig455_030510

Neo: -

Age: -

 0.983 - - - - - 0.983 Mlig455_030510 {REF} {Length: 1004} {RNA1509_42280} {RNA1310_51836} {RNA815_8810.1}
88. MligTC455_34253 1073 22.35 Mlig455_035968

Neo: -

Age: -

Region-enriched R5: 1.204/0.04277

 PGK1 0.983 - - - - - 0.983 Mlig455_035968 {REF} {Length: 2381} {Pfam: Phosphoglycerate kinase [PF00162.21, score=488.1]} {Human: ENSG00000102144, PGK1, phosphoglycerate kinase 1, [RH, Score=588, Expect=0.0]; ENSG00000170950, PGK2, phosphoglycerate kinase 2, [RH, Score=585, Expect=0.0]} {Mouse: ENSMUSG00000062070, Pgk1, phosphoglycerate kinase 1, [RH, Score=587, Expect=0.0]; ENSMUSG00000031233, Pgk2, phosphoglycerate kinase 2, [RH, Score=572, Expect=0.0]} {Dmel: FBgn0250906, Pgk, Phosphoglycerate kinase, [RH, Score=562, Expect=0.0]} {Celegans: WBGene00020185, pgk-1, Probable phosphoglycerate kinase, [RH, Score=605, Expect=0.0]} {Smed: dd_Smed_v6_972_0_1, dd_Smed_v6_972_0_1, [RH, Score=602, Expect=0.0]} {RNA1509_1929, RNA1509_24971} {RNA1310_10765.1, RNA1509_1929, RNA1509_24971} {RNA1509_1929, RNA1509_24971, RNA815_5032.1}
89. MligTC455_35834 86 1.8 Mlig455_011961

Neo: -

Age: -

 CES4A 0.983 - - - - 0.983 - Mlig455_011961 {REF} {Length: 3668} {Pfam: Carboxylesterase family [PF00135.30, score=101.0]} {Human: ENSG00000172824, CES4A, carboxylesterase 4A, [Score=79.0, Expect=9e-15]} {Mouse: ENSMUSG00000050097, Ces2b, carboxyesterase 2B, [Score=81.6, Expect=1e-15]; ENSMUSG00000061825, Ces2c, carboxylesterase 2C, [Score=81.6, Expect=1e-15]} {Dmel: FBgn0004108, Nrt, Neurotactin, [RH, Score=104, Expect=7e-23]} {Celegans: WBGene00019477, K07C11.4, Carboxylic ester hydrolase, [Score=77.0, Expect=2e-14]} {Smed: dd_Smed_v6_4800_0_2, dd_Smed_v6_4800_0_2, [Score=56.6, Expect=4e-08]} {RNA1310_8940} {RNA815_4325.1}
90. MligTC455_36069 93 1.94 Mlig455_054357

Neo: -

Age: -

 C17orf97 0.983 - - - - - 0.983 Mlig455_054357 {REF} {Length: 1067} {Human: ENSG00000187624, C17orf97, chromosome 17 open reading frame 97, [Score=45.8, Expect=7e-06]; ENSG00000283985, C17orf97, chromosome 17 open reading frame 97, [Score=45.8, Expect=7e-06]} {RNA1509_48416} {RNA1310_106903}
91. MligTC455_11937 120 2.5 Mlig455_057568

Neo: -

Age: logFC(26M/2M)=-0.768

 SGK494 0.982 - - - - - 0.982 Mlig455_057568 {REF} {Length: 3677} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=181.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=88.0]; Phosphotransferase enzyme family [PF01636.25, score=21.2]; Kinase-like [PF14531.8, score=19.6]} {Human: ENSG00000167524, SGK494, uncharacterized serine/threonine-protein kinase SgK494, [RH, Score=207, Expect=2e-61]} {Mouse: ENSMUSG00000024830, Rps6kb2, ribosomal protein S6 kinase, polypeptide 2, [Score=172, Expect=1e-47]; ENSMUSG00000097721, Rps6kb2, ribosomal protein S6 kinase, polypeptide 2, [Score=172, Expect=1e-47]; ENSMUSG00000020516, Rps6kb1, ribosomal protein S6 kinase, polypeptide 1, [Score=170, Expect=2e-46]; ENSMUSG00000029053, Prkcz, protein kinase C, zeta, [Score=167, Expect=1e-46]} {Dmel: FBgn0283473, S6KL, S6 Kinase Like, [RH, Score=196, Expect=7e-57]} {Celegans: WBGene00017950, F31E3.2, Putative serine/threonine-protein kinase F31E3.2, [RH, Score=202, Expect=1e-59]} {Smed: dd_Smed_v6_7868_0_1, dd_Smed_v6_7868_0_1, [RH, Score=291, Expect=2e-92]} {RNA1509_34459, RNA1509_53338} {RNA1310_14015.2, RNA1509_34459, RNA1509_53338} {RNA1509_34459, RNA1509_53338, RNA815_17648}
92. MligTC455_15137 390 8.12 Mlig455_067270

Neo: -

Age: -

 RALGPS1 0.982 - - - - - 0.982 Mlig455_067270 {REF} {Length: 3938} {TRANSSPLICED} {Pfam: RasGEF domain [PF00617.21, score=146.0]} {Human: ENSG00000136828, RALGPS1, Ral GEF with PH domain and SH3 binding motif 1, [Score=249, Expect=6e-75]; ENSG00000116191, RALGPS2, Ral GEF with PH domain and SH3 binding motif 2, [Score=249, Expect=6e-73]} {Mouse: ENSMUSG00000026594, Ralgps2, Ral GEF with PH domain and SH3 binding motif 2, [Score=249, Expect=1e-72]; ENSMUSG00000038831, Ralgps1, Ral GEF with PH domain and SH3 binding motif 1, [Score=244, Expect=3e-71]} {Dmel: FBgn0034158, CG5522, [Score=241, Expect=8e-69]} {Celegans: WBGene00017891, rgl-1, Ral GDS-Like, [Score=70.9, Expect=2e-12]} {Smed: dd_Smed_v6_9244_0_1, dd_Smed_v6_9244_0_1, [Score=212, Expect=2e-57]} {RNA1509_15882, RNA1509_34707, RNA1509_39035} {RNA1310_18426, RNA1509_34707, RNA1509_39035} {RNA1509_34707, RNA1509_39035, RNA815_13855.1}
93. MligTC455_24734 91 1.9 Mlig455_009844, Mlig455_010343

Neo: -

Age: -

 ABHD16A 0.982 - - - - - 0.982

Mlig455_009844 {REF} {Length: 1123} {TRANSSPLICED} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=28.7]; Serine aminopeptidase, S33 [PF12146.10, score=19.6]} {Human: ENSG00000235676, ABHD16A, abhydrolase domain containing 16A, [Score=250, Expect=4e-77]; ENSG00000231488, ABHD16A, abhydrolase domain containing 16A, [Score=250, Expect=4e-77]; ENSG00000224552, ABHD16A, abhydrolase domain containing 16A, [Score=250, Expect=4e-77]; ENSG00000230475, ABHD16A, abhydrolase domain containing 16A, [Score=250, Expect=4e-77]; ENSG00000236063, ABHD16A, abhydrolase domain containing 16A, [Score=250, Expect=4e-77]; ENSG00000204427, ABHD16A, abhydrolase domain containing 16A, [Score=249, Expect=2e-77]; ENSG00000206403, ABHD16A, abhydrolase domain containing 16A, [Score=249, Expect=2e-77]} {Mouse: ENSMUSG00000007036, Abhd16a, abhydrolase domain containing 16A, [Score=248, Expect=7e-77]} {Dmel: FBgn0035519, CG1309, [Score=211, Expect=4e-63]} {Celegans: WBGene00018131, F37A4.1, [Score=142, Expect=5e-38]} {Smed: dd_Smed_v6_4938_0_1, dd_Smed_v6_4938_0_1, [Score=258, Expect=8e-82]} {RNA1509_24382} {RNA1310_12083} {RNA815_4499}

Mlig455_010343 {REF} {Length: 1791} {TRANSSPLICED} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=27.7]; Serine aminopeptidase, S33 [PF12146.10, score=22.6]} {Human: ENSG00000236063, ABHD16A, abhydrolase domain containing 16A, [RH, Score=360, Expect=1e-116]; ENSG00000230475, ABHD16A, abhydrolase domain containing 16A, [RH, Score=360, Expect=1e-116]; ENSG00000206403, ABHD16A, abhydrolase domain containing 16A, [RH, Score=360, Expect=3e-117]; ENSG00000204427, ABHD16A, abhydrolase domain containing 16A, [RH, Score=360, Expect=3e-117]; ENSG00000224552, ABHD16A, abhydrolase domain containing 16A, [RH, Score=360, Expect=1e-116]; ENSG00000231488, ABHD16A, abhydrolase domain containing 16A, [RH, Score=360, Expect=1e-116]; ENSG00000235676, ABHD16A, abhydrolase domain containing 16A, [RH, Score=360, Expect=1e-116]} {Mouse: ENSMUSG00000007036, Abhd16a, abhydrolase domain containing 16A, [RH, Score=352, Expect=2e-114]} {Dmel: FBgn0035519, CG1309, [RH, Score=288, Expect=3e-90]} {Celegans: WBGene00018131, F37A4.1, [RH, Score=201, Expect=9e-58]} {Smed: dd_Smed_v6_4938_0_1, dd_Smed_v6_4938_0_1, [RH, Score=347, Expect=8e-113]} {RNA1509_24382, RNA1509_5905} {RNA1310_12083, RNA1509_5905} {RNA1509_5905, RNA815_4499}
94. MligTC455_26024 76 1.59 Mlig455_053501

Neo: -

Age: -

 TBC1D10A 0.982 - - - - - 0.982 Mlig455_053501 {REF} {Length: 2786} {TRANSSPLICED} {Pfam: Rab-GTPase-TBC domain [PF00566.20, score=157.9]} {Human: ENSG00000099992, TBC1D10A, TBC1 domain family member 10A, [RH, Score=283, Expect=4e-91]; ENSG00000169221, TBC1D10B, TBC1 domain family member 10B, [RH, Score=281, Expect=3e-87]} {Mouse: ENSMUSG00000034412, Tbc1d10a, TBC1 domain family, member 10a, [RH, Score=282, Expect=6e-91]; ENSMUSG00000042492, Tbc1d10b, TBC1 domain family, member 10b, [RH, Score=281, Expect=2e-87]} {Dmel: FBgn0037917, wkd, whacked, [RH, Score=287, Expect=1e-94]} {Celegans: WBGene00019915, tbc-10, TBC (Tre-2/Bub2/Cdc16) domain family, [RH, Score=258, Expect=2e-82]} {Smed: dd_Smed_v6_5522_0_2, dd_Smed_v6_5522_0_2, [RH, Score=283, Expect=2e-93]} {RNA1509_35338} {RNA1310_28912} {RNA815_18847}
95. MligTC455_28351 118 2.46 Mlig455_031888

Neo: -

Age: logFC(26M/2M)=0.863

 0.982 - - - - - 0.982 Mlig455_031888 {REF} {Length: 2640} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=66.6, Expect=8e-13]} {RNA1509_7841} {RNA1310_18810} {RNA815_3607}
96. MligTC455_29018 1803 37.56 Mlig455_033521

Neo: -

Age: -

 0.982 - - - - - 0.982 Mlig455_033521 {REF} {Length: 44} {NoTransDecoderORF}
97. MligTC455_30229 85 1.77 Mlig455_050775

Neo: -

Age: -

 0.982 - - - - - 0.982 Mlig455_050775 {REF} {Length: 6509} {TRANSSPLICED} {Pfam: Helitron helicase-like domain at N-terminus [PF14214.8, score=176.6]} {Celegans: WBGene00021577, Y46B2A.2, [Score=445, Expect=3e-138]} {Smed: dd_Smed_v6_91935_0_1, dd_Smed_v6_91935_0_1, [Score=68.9, Expect=1e-13]} {RNA1509_5036} {RNA1310_4048.1} {RNA815_356.1}
98. MligTC455_45501 74 1.55 Mlig455_056444

Neo: -

Age: -

 0.982 - - - - - 0.982 Mlig455_056444 {REF} {Length: 2020} {RNA1509_53357} {RNA1310_37383} {RNA815_27630}
99. MligTC455_46671 96 2 Mlig455_034858

Neo: -

Age: -

 0.982 - - - - - 0.982 Mlig455_034858 {REF} {Length: 1282} {NoTransDecoderORF} {RNA1509_31366} {RNA1310_58603, RNA1509_31366} {RNA1509_31366, RNA815_9852.1}
100. MligTC455_51322 354 7.37 Mlig455_009426

Neo: -

Age: Up-Down-Down

 0.982 - - - - - 0.982 Mlig455_009426 {REF} {Length: 2420} {TRANSSPLICED} {RNA1310_11295.1} {RNA815_14627}

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