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Results for MligTC455_47647

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_47647 386 8.05 Mlig455_039025, Mlig455_039029

Neo: -

Age: Down-Up-Down

Region-enriched R8: 8.248/0.00000
Region-enriched R2: 6.877/0.00091
Region-enriched R7: 4.106/0.01478

Mlig455_039025 {REF} {Length: 996} {NoTransDecoderORF} {RNA1509_17584, RNA1509_53722, RNA1509_59811} {RNA1310_35546, RNA1509_17584, RNA1509_53722, RNA1509_59811} {RNA1509_17584, RNA1509_53722, RNA1509_59811, RNA815_23548}

Mlig455_039029 {REF} {Length: 557} {NoTransDecoderORF} {RNA1509_17584} {RNA1310_35546} {RNA815_23548}

Cumulative graph for MligTC455_47647

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -14.223 3.394 0.00178 0.13638
RegionR2 6.877 3.394 0.00001 0.00091
RegionR3 1.697 3.394 0.34446 0.87993
RegionR4 -5.909 3.394 0.99974 1.00000
RegionR5 -2.004 3.394 0.99991 1.00000
RegionR6 1.206 3.394 0.40968 0.97894
RegionR7 4.106 3.394 0.00033 0.01478
RegionR8 8.248 3.394 0.00000 0.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 7.882 3.394 0.99975 1.00000
RegenerationR2 -1.412 3.394 0.21171 0.65884
RegenerationR3 -1.148 3.394 0.41430 0.81149
RegenerationR4 -0.358 3.394 0.52143 0.87970
RegenerationR5 -2.099 3.394 0.15206 0.57076
RegenerationR6 -1.492 3.394 0.25696 0.60698
RegenerationBL -6.671 3.394 0.01574 0.13238
RegenerationTP -4.199 3.394 0.02069 0.24661


Genes with expression patterns similar to MligTC455_47647

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_47647 386 8.05 Mlig455_039025, Mlig455_039029

Neo: -

Age: Down-Up-Down

Region-enriched R8: 8.248/0.00000
Region-enriched R2: 6.877/0.00091
Region-enriched R7: 4.106/0.01478

 3 1.000 1.000 - - 1.000 -

Mlig455_039025 {REF} {Length: 996} {NoTransDecoderORF} {RNA1509_17584, RNA1509_53722, RNA1509_59811} {RNA1310_35546, RNA1509_17584, RNA1509_53722, RNA1509_59811} {RNA1509_17584, RNA1509_53722, RNA1509_59811, RNA815_23548}

Mlig455_039029 {REF} {Length: 557} {NoTransDecoderORF} {RNA1509_17584} {RNA1310_35546} {RNA815_23548}
2. MligTC455_16170 1538 32.03 Mlig455_036607, Mlig455_036647

Neo: -

Age: -

 2.525 0.954 0.809 - - 0.762 -

Mlig455_036607 {REF} {Length: 1999} {Pfam: Methyltransferase domain [PF13489.8, score=20.5]; Methyltransferase domain [PF08242.14, score=20.1]} {Smed: dd_Smed_v6_14238_0_1, dd_Smed_v6_14238_0_1, [RH, Score=150, Expect=5e-42]} {RNA1509_11037, RNA1509_43345} {RNA1310_20809.1, RNA1509_11037, RNA1509_43345} {RNA1509_11037, RNA1509_43345, RNA815_14638}

Mlig455_036647 {REF} {Length: 2335} {Pfam: Methyltransferase domain [PF13489.8, score=20.6]; Methyltransferase domain [PF08242.14, score=20.1]} {Smed: dd_Smed_v6_14238_0_1, dd_Smed_v6_14238_0_1, [RH, Score=149, Expect=1e-41]} {RNA1509_11037} {RNA1310_17014} {RNA815_14638}
3. MligTC455_27627 225 4.69 Mlig455_065807

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.382

 HEYL 2.456 0.957 0.746 - - 0.753 - Mlig455_065807 {REF} {Length: 1800} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=45.1]; Hairy Orange [PF07527.15, score=20.8]} {Human: ENSG00000163909, HEYL, hes related family bHLH transcription factor with YRPW motif-like, [Score=85.9, Expect=2e-18]; ENSG00000135547, HEY2, hes related family bHLH transcription factor with YRPW motif 2, [Score=85.5, Expect=2e-18]} {Mouse: ENSMUSG00000019789, Hey2, hairy/enhancer-of-split related with YRPW motif 2, [Score=86.3, Expect=2e-18]; ENSMUSG00000032744, Heyl, hairy/enhancer-of-split related with YRPW motif-like, [Score=85.5, Expect=2e-18]} {Dmel: FBgn0259938, cwo, clockwork orange, [RH, Score=84.0, Expect=2e-17]} {Smed: dd_Smed_v6_22479_0_1, dd_Smed_v6_22479_0_1, [Score=70.9, Expect=9e-14]} {RNA1509_35089} {RNA1310_373, RNA1509_35089} {RNA1509_35089, RNA815_5586}
4. MligTC455_26263 70 1.45 Mlig455_040654

Neo: -

Age: Up-Down-Down

 NR1I3 1.897 0.950 - - - 0.947 - Mlig455_040654 {REF} {Length: 4785} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.2]} {Human: ENSG00000143257, NR1I3, nuclear receptor subfamily 1 group I member 3, [Score=103, Expect=1e-23]} {Mouse: ENSMUSG00000005677, Nr1i3, nuclear receptor subfamily 1, group I, member 3, [Score=99.8, Expect=3e-22]; ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=99.4, Expect=1e-21]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=95.5, Expect=2e-20]} {Dmel: FBgn0015240, Hr96, Hormone receptor-like in 96, [Score=98.2, Expect=7e-21]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=112, Expect=2e-25]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=183, Expect=2e-50]} {RNA1509_15212} {RNA1310_18440} {RNA815_11206}
5. MligTC455_30298 374 7.79 Mlig455_043411, Mlig455_043553

Neo: -

Age: -

 1.895 0.972 - - - 0.923 -

Mlig455_043411 {REF} {Length: 5334} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=68.9]; Tetratricopeptide repeat [PF13181.8, score=29.2]; AAA ATPase domain [PF13191.8, score=26.2]; Tetratricopeptide repeat [PF07719.19, score=26.0]; Tetratricopeptide repeat [PF14559.8, score=25.5]; Tetratricopeptide repeat [PF00515.30, score=24.6]; NACHT domain [PF05729.14, score=23.4]; Tetratricopeptide repeat [PF13374.8, score=21.8]} {Mouse: ENSMUSG00000044937, Ttc41, tetratricopeptide repeat domain 41, [Score=133, Expect=1e-30]} {Smed: dd_Smed_v6_12326_0_4, dd_Smed_v6_12326_0_4, [Score=203, Expect=9e-53]} {RNA1509_11012} {RNA1310_2964, RNA1509_11012} {RNA1509_11012, RNA815_1508.1}

Mlig455_043553 {REF} {Length: 5340} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=68.0]; Tetratricopeptide repeat [PF13181.8, score=28.2]; AAA ATPase domain [PF13191.8, score=26.2]; Tetratricopeptide repeat [PF00515.30, score=25.3]; Tetratricopeptide repeat [PF14559.8, score=25.2]; Tetratricopeptide repeat [PF07719.19, score=24.6]; NACHT domain [PF05729.14, score=23.0]; Tetratricopeptide repeat [PF13374.8, score=21.0]; Zeta toxin [PF06414.14, score=20.0]} {Mouse: ENSMUSG00000044937, Ttc41, tetratricopeptide repeat domain 41, [RH, Score=187, Expect=1e-47]} {Smed: dd_Smed_v6_12326_0_3, dd_Smed_v6_12326_0_3, [RH, Score=218, Expect=3e-57]} {RNA1509_11012} {RNA1310_2964} {RNA815_1508.1}
6. MligTC455_25642 404 8.41 Mlig455_055674

Neo: -

Age: logFC(26M/2M)=-0.267

Regeneration-downregulated BL: -3.906

Regeneration-depleted BL: -3.906

 TRAF3 1.893 0.973 - - - 0.920 - Mlig455_055674 {REF} {Length: 3425} {Pfam: TRAF-type zinc finger [PF02176.20, score=35.2]; Seven in absentia protein family [PF03145.18, score=32.2]} {Human: ENSG00000131323, TRAF3, TNF receptor associated factor 3, [Score=68.9, Expect=2e-11]} {Mouse: ENSMUSG00000021277, Traf3, TNF receptor-associated factor 3, [Score=75.5, Expect=1e-13]; ENSMUSG00000027164, Traf6, TNF receptor-associated factor 6, [Score=72.0, Expect=1e-12]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=58.5, Expect=1e-08]} {Smed: dd_Smed_v6_8046_0_1, dd_Smed_v6_8046_0_1, [Score=79.0, Expect=4e-15]} {RNA1509_45640} {RNA1310_11522} {RNA815_6004}
7. MligTC455_30297 190 3.95 Mlig455_043386

Neo: -

Age: -

 1.889 0.965 - - - 0.924 - Mlig455_043386 {REF} {Length: 3325} {Pfam: Tetratricopeptide repeat [PF13424.8, score=72.0]; Tetratricopeptide repeat [PF13181.8, score=32.7]; Tetratricopeptide repeat [PF07719.19, score=29.8]; Tetratricopeptide repeat [PF00515.30, score=29.6]; Tetratricopeptide repeat [PF14559.8, score=27.0]; Tetratricopeptide repeat [PF13374.8, score=24.9]; Tetratricopeptide repeat [PF13428.8, score=20.2]; Tetratricopeptide repeat [PF13432.8, score=19.8]} {Smed: dd_Smed_v6_12326_0_3, dd_Smed_v6_12326_0_3, [Score=87.0, Expect=3e-17]} {RNA1509_11012} {RNA1310_2964} {RNA815_1508.1}
8. MligTC455_05193 189 3.94 Mlig455_013094

Neo: -

Age: Down-Up-Down

 BCHE 1.876 0.904 - - - 0.972 - Mlig455_013094 {REF} {Length: 2979} {Pfam: Carboxylesterase family [PF00135.30, score=435.7]; alpha/beta hydrolase fold [PF07859.15, score=35.5]} {Human: ENSG00000114200, BCHE, butyrylcholinesterase, [RH, Score=319, Expect=5e-100]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [RH, Score=334, Expect=3e-105]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=253, Expect=3e-74]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [RH, Score=332, Expect=2e-104]} {Smed: dd_Smed_v6_15930_0_1, dd_Smed_v6_15930_0_1, [RH, Score=416, Expect=5e-136]} {RNA1509_5880} {RNA1310_9146.1} {RNA815_3169.2}
9. MligTC455_34893 231 4.8 Mlig455_066819

Neo: -

Age: Down-Up-Down

 CYP2U1 1.875 0.952 - - - 0.923 - Mlig455_066819 {REF} {Length: 1584} {Pfam: Cytochrome P450 [PF00067.24, score=109.5]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=95.5, Expect=9e-24]; ENSG00000186104, CYP2R1, cytochrome P450 family 2 subfamily R member 1, [Score=92.4, Expect=3e-22]; ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=91.3, Expect=9e-22]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=91.3, Expect=6e-22]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=90.5, Expect=1e-21]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=90.5, Expect=1e-21]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=90.1, Expect=1e-21]; ENSMUSG00000030670, Cyp2r1, cytochrome P450, family 2, subfamily r, polypeptide 1, [Score=89.7, Expect=4e-22]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [Score=89.0, Expect=3e-21]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=87.8, Expect=1e-20]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [Score=87.4, Expect=1e-20]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=76.3, Expect=9e-17]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [Score=89.0, Expect=2e-21]} {Smed: dd_Smed_v6_5344_0_2, dd_Smed_v6_5344_0_2, [Score=102, Expect=4e-26]} {RNA1509_39728} {RNA1310_10949.2} {RNA815_7611}
10. MligTC455_46347 760 15.83 Mlig455_023024

Neo: -

Age: Down-Up-Up

 ELOF1 1.866 0.912 - - - 0.954 - Mlig455_023024 {REF} {Length: 1056} {TRANSSPLICED} {Pfam: Transcription elongation factor Elf1 like [PF05129.15, score=104.0]} {Human: ENSG00000130165, ELOF1, elongation factor 1 homolog, [RH, Score=102, Expect=2e-29]} {Mouse: ENSMUSG00000013822, Elof1, ELF1 homolog, elongation factor 1, [RH, Score=101, Expect=1e-29]} {Dmel: FBgn0063670, CG40228, [RH, Score=133, Expect=2e-42]} {Celegans: WBGene00013219, Y54G11A.11, Transcription elongation factor 1 homolog, [RH, Score=134, Expect=6e-43]} {Smed: dd_Smed_v6_3505_0_1, dd_Smed_v6_3505_0_1, [RH, Score=122, Expect=2e-38]} {RNA1509_44595, RNA1509_9167} {RNA1310_32925, RNA1509_44595} {RNA1509_44595, RNA815_15186.1}
11. MligTC455_05194 106 2.21 Mlig455_013187

Neo: -

Age: -

 BCHE 1.865 0.905 - - - 0.960 - Mlig455_013187 {REF} {Length: 3411} {Pfam: Carboxylesterase family [PF00135.30, score=439.9]; alpha/beta hydrolase fold [PF07859.15, score=35.8]} {Human: ENSG00000114200, BCHE, butyrylcholinesterase, [RH, Score=320, Expect=3e-100]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [RH, Score=335, Expect=1e-105]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=250, Expect=2e-73]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=330, Expect=9e-104]} {Smed: dd_Smed_v6_15930_0_1, dd_Smed_v6_15930_0_1, [RH, Score=423, Expect=9e-139]} {RNA1509_5880} {RNA1310_9146.1} {RNA815_3169.2}
12. MligTC455_14380 59 1.24 Mlig455_030609

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.006

 GIMAP4 1.865 0.954 - - - 0.911 - Mlig455_030609 {REF} {Length: 1770} {Pfam: AIG1 family [PF04548.18, score=134.8]; Hint module [PF01079.22, score=100.7]; 50S ribosome-binding GTPase [PF01926.25, score=36.6]; Dynamin family [PF00350.25, score=24.1]; Septin [PF00735.20, score=23.0]; Elongation factor Tu GTP binding domain [PF00009.29, score=21.1]; AAA ATPase domain [PF13191.8, score=20.6]; Interferon-inducible GTPase (IIGP) [PF05049.15, score=19.3]} {Human: ENSG00000133574, GIMAP4, GTPase, IMAP family member 4, [RH, Score=101, Expect=7e-23]; ENSG00000281887, GIMAP1-GIMAP5, GIMAP1-GIMAP5 readthrough, [RH, Score=98.6, Expect=2e-21]; ENSG00000179144, GIMAP7, GTPase, IMAP family member 7, [RH, Score=97.4, Expect=7e-22]} {Mouse: ENSMUSG00000051124, Gimap9, GTPase, IMAP family member 9, [RH, Score=107, Expect=2e-25]} {Celegans: WBGene00004264, qua-1, [RH, Score=75.1, Expect=5e-14]} {RNA1509_32162} {RNA1310_22876} {RNA815_14108}
13. MligTC455_44594 694 14.45 Mlig455_002373

Neo: -

Age: Down-Up-Down

 SOX21 1.847 0.955 - - - 0.892 - Mlig455_002373 {REF} {Length: 2315} {TRANSSPLICED} {Pfam: HMG (high mobility group) box [PF00505.21, score=89.4]; HMG-box domain [PF09011.12, score=40.9]} {Human: ENSG00000125285, SOX21, SRY-box 21, [Score=108, Expect=4e-27]; ENSG00000181449, SOX2, SRY-box 2, [Score=108, Expect=5e-27]; ENSG00000168875, SOX14, SRY-box 14, [Score=108, Expect=2e-27]; ENSG00000182968, SOX1, SRY-box 1, [Score=107, Expect=6e-26]; ENSG00000134595, SOX3, SRY-box 3, [Score=106, Expect=2e-25]; ENSG00000005513, SOX8, SRY-box 8, [Score=106, Expect=2e-25]} {Mouse: ENSMUSG00000053747, Sox14, SRY (sex determining region Y)-box 14, [Score=108, Expect=1e-27]; ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [Score=108, Expect=3e-27]; ENSMUSG00000061517, Sox21, SRY (sex determining region Y)-box 21, [Score=108, Expect=3e-27]; ENSMUSG00000024176, Sox8, SRY (sex determining region Y)-box 8, [Score=107, Expect=6e-26]; ENSMUSG00000096014, Sox1, SRY (sex determining region Y)-box 1, [Score=107, Expect=5e-26]; ENSMUSG00000045179, Sox3, SRY (sex determining region Y)-box 3, [Score=106, Expect=1e-25]; ENSMUSG00000041287, Sox15, SRY (sex determining region Y)-box 15, [Score=104, Expect=2e-26]} {Dmel: FBgn0000411, D, dachs, [Score=115, Expect=3e-29]} {Celegans: WBGene00015716, sox-4, SOX (Mammalian SRY box) family, [RH, Score=106, Expect=2e-27]} {Smed: dd_Smed_v6_8104_0_1, dd_Smed_v6_8104_0_1, [Score=111, Expect=2e-27]} {RNA1509_37296} {RNA1310_8726.1} {RNA815_5231}
14. MligTC455_19085 95 1.98 Mlig455_021540

Neo: -

Age: -

 1.843 0.883 - - - 0.960 - Mlig455_021540 {REF} {Length: 2045} {RNA1509_39251} {RNA1310_9860} {RNA815_3403}
15. MligTC455_35002 390 8.12 Mlig455_070372

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.711

 SVEP1 1.837 0.975 - - - 0.862 - Mlig455_070372 {REF} {Length: 1042} {Pfam: EGF-like domain [PF00008.29, score=33.8]; EGF-like domain [PF07974.15, score=21.9]} {Human: ENSG00000165124, SVEP1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=51.6, Expect=3e-07]; ENSG00000148400, NOTCH1, notch 1, [Score=51.2, Expect=4e-07]} {Mouse: ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=58.9, Expect=5e-10]} {Dmel: FBgn0004647, N, Notch, [Score=50.1, Expect=4e-07]} {RNA1509_29817} {RNA1310_28236} {RNA815_11876.1}
16. MligTC455_48102 1320 27.5 Mlig455_006219

Neo: -

Age: logFC(26M/2M)=-0.310

Region-enriched R8: 1.245/0.04204

 RGS22 1.817 0.841 - - - 0.976 - Mlig455_006219 {REF} {Length: 6168} {TRANSSPLICED} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=73.0]} {Human: ENSG00000132554, RGS22, regulator of G protein signaling 22, [RH, Score=69.7, Expect=5e-11]} {Mouse: ENSMUSG00000037627, Rgs22, regulator of G-protein signalling 22, [RH, Score=59.3, Expect=4e-08]} {Smed: dd_Smed_v6_11778_0_1, dd_Smed_v6_11778_0_1, [Score=365, Expect=5e-105]} {RNA1509_2536} {RNA1310_2017.1} {RNA815_616.1}
17. MligTC455_16059 116 2.42 Mlig455_044225

Neo: -

Age: -

 CFAP157 1.815 0.845 - - - 0.970 - Mlig455_044225 {REF} {Length: 2823} {Pfam: Siphovirus Gp157 [PF05565.13, score=19.9]} {Human: ENSG00000160401, CFAP157, cilia and flagella associated protein 157, [Score=107, Expect=3e-24]} {Mouse: ENSMUSG00000038987, Cfap157, cilia and flagella associated protein 157, [Score=110, Expect=4e-25]} {Dmel: FBgn0036962, CG17122, [Score=67.4, Expect=2e-11]} {Smed: dd_Smed_v6_11523_0_1, dd_Smed_v6_11523_0_1, [Score=62.0, Expect=4e-10]} {RNA1509_42697} {RNA1310_10711} {RNA815_24261}
18. MligTC455_50024 354 7.37 Mlig455_003621, Mlig455_070701

Neo: -

Age: Down-Up-Down

 ATF7IP 1.797 0.971 - - - 0.826 -

Mlig455_003621 {REF} {Length: 4513} {TRANSSPLICED} {Pfam: Fibronectin-III type domain [PF16794.7, score=92.7]} {Human: ENSG00000171681, ATF7IP, activating transcription factor 7 interacting protein, [RH, Score=103, Expect=8e-22]} {Mouse: ENSMUSG00000030213, Atf7ip, activating transcription factor 7 interacting protein, [RH, Score=101, Expect=2e-21]} {Dmel: FBgn0027499, wde, windei, [RH, Score=90.9, Expect=3e-18]} {Smed: dd_Smed_v6_9372_0_1, dd_Smed_v6_9372_0_1, [RH, Score=75.5, Expect=2e-14]} {RNA1509_10271, RNA1509_53701} {RNA1310_5928.1, RNA1509_53701} {RNA1509_53701, RNA815_4314.1}

Mlig455_070701 {REF} {Length: 4470} {TRANSSPLICED} {RNA1509_10271} {RNA1310_5928.1} {RNA815_4314.1}
19. MligTC455_49526 450 9.38 Mlig455_050949

Neo: -

Age: logFC(26M/2M)=-0.615

 CALM2 1.776 0.813 - - - 0.963 - Mlig455_050949 {REF} {Length: 3680} {Pfam: EF-hand domain pair [PF13499.8, score=87.8]; EF hand [PF00036.34, score=79.8]; EF-hand domain [PF13405.8, score=67.4]; EF hand [PF13202.8, score=65.4]; EF-hand domain pair [PF13833.8, score=60.3]; EF-hand domain [PF08976.13, score=22.2]; EF-hand domain [PF14658.8, score=21.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=20.9]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=18.9]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=100, Expect=5e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=100, Expect=5e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=100, Expect=5e-24]; ENSG00000178363, CALML3, calmodulin like 3, [Score=99.4, Expect=8e-24]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=103, Expect=9e-25]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=102, Expect=4e-25]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=100, Expect=3e-24]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=100, Expect=3e-24]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=99.0, Expect=6e-24]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=102, Expect=4e-25]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=100, Expect=1e-24]} {RNA1509_48556} {RNA1310_10152.1} {RNA815_3673.1}
20. MligTC455_30611 129 2.68 Mlig455_031173

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.392

Region-enriched R8: 4.530/0.01124

 ITPR1 1.761 0.964 - - - 0.797 - Mlig455_031173 {REF} {Length: 9349} {Pfam: RIH domain [PF01365.23, score=93.2]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=76.6]; RyR and IP3R Homology associated [PF08454.13, score=72.8]; MIR domain [PF02815.21, score=44.1]; Ion transport protein [PF00520.33, score=31.9]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=239, Expect=4e-62]; ENSG00000123104, ITPR2, inositol 1,4,5-trisphosphate receptor type 2, [Score=229, Expect=2e-59]} {Mouse: ENSMUSG00000042644, Itpr3, inositol 1,4,5-triphosphate receptor 3, [Score=241, Expect=7e-63]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=202, Expect=3e-51]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=174, Expect=7e-43]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1868, Expect=0.0]} {RNA1509_5518} {RNA1310_129.1} {RNA815_62.1}
21. MligTC455_27365 3903 81.32 Mlig455_008275

Neo: -

Age: -

Region-enriched R4: 3.124/0.00001
Region-enriched R8: 1.668/0.04043

 1.747 0.975 - - - 0.772 - Mlig455_008275 {REF} {Length: 1620} {RNA1509_1252} {RNA1310_61787} {RNA815_19934.1}
22. MligTC455_33995 174 3.63 Mlig455_042151

Neo: -

Age: logFC(26M/2M)=-0.705

 ANK1 1.74 0.969 - - - 0.771 - Mlig455_042151 {REF} {Length: 8174} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=414.4]; Ankyrin repeats (many copies) [PF13637.8, score=253.9]; Ankyrin repeats (many copies) [PF13857.8, score=156.9]; Ankyrin repeat [PF13606.8, score=149.6]; Ankyrin repeat [PF00023.32, score=87.1]; Family of unknown function (DUF6189) [PF19688.1, score=71.1]; 3,4-dihydroxy-2-butanone 4-phosphate synthase [PF00926.21, score=44.8]; Domain of unknown function (DUF6487) [PF20097.1, score=28.5]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=81.6, Expect=1e-14]} {Mouse: ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=71.6, Expect=9e-12]; ENSMUSG00000014498, Ankrd52, ankyrin repeat domain 52, [Score=68.2, Expect=9e-11]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=65.5, Expect=4e-10]} {RNA1509_28890} {RNA1310_16696.1, RNA1509_28890} {RNA1509_28890, RNA815_12859.1}
23. MligTC455_43834 628 13.08 Mlig455_024930

Neo: -

Age: -

 SOX14 1.713 0.968 - - - 0.745 - Mlig455_024930 {REF} {Length: 5050} {TRANSSPLICED} {Pfam: HMG (high mobility group) box [PF00505.21, score=86.2]; HMG-box domain [PF09011.12, score=43.1]} {Human: ENSG00000168875, SOX14, SRY-box 14, [Score=109, Expect=2e-27]; ENSG00000125285, SOX21, SRY-box 21, [Score=107, Expect=1e-26]; ENSG00000129194, SOX15, SRY-box 15, [Score=104, Expect=1e-25]; ENSG00000181449, SOX2, SRY-box 2, [Score=104, Expect=4e-25]} {Mouse: ENSMUSG00000053747, Sox14, SRY (sex determining region Y)-box 14, [Score=109, Expect=1e-27]; ENSMUSG00000061517, Sox21, SRY (sex determining region Y)-box 21, [Score=107, Expect=9e-27]; ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [Score=104, Expect=3e-25]} {Dmel: FBgn0000411, D, dachs, [Score=116, Expect=3e-29]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [Score=107, Expect=1e-26]} {Smed: dd_Smed_v6_36521_0_1, dd_Smed_v6_36521_0_1, [Score=103, Expect=4e-25]} {RNA1509_6414} {RNA1310_19145.1} {RNA815_3816.1}
24. MligTC455_13512 156 3.24 Mlig455_020307

Neo: -

Age: -

 CNGA3 1.699 0.973 0.726 - - - - Mlig455_020307 {REF} {Length: 3017} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=63.0]; Ion transport protein [PF00520.33, score=56.3]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [Score=430, Expect=3e-138]; ENSG00000183862, CNGA2, cyclic nucleotide gated channel alpha 2, [Score=412, Expect=6e-132]; ENSG00000198515, CNGA1, cyclic nucleotide gated channel alpha 1, [Score=412, Expect=2e-131]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [Score=414, Expect=6e-133]; ENSMUSG00000067220, Cnga1, cyclic nucleotide gated channel alpha 1, [Score=410, Expect=6e-131]; ENSMUSG00000005864, Cnga2, cyclic nucleotide gated channel alpha 2, [Score=402, Expect=3e-128]} {Dmel: FBgn0259145, CG42260, [RH, Score=652, Expect=0.0]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [Score=352, Expect=7e-109]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [Score=404, Expect=1e-129]} {RNA1509_58266} {RNA1310_19338} {RNA815_12776}
25. MligTC455_44442 1201 25.03 Mlig455_003131

Neo: -

Age: logFC(26M/2M)=-0.363

 1.693 0.721 - - - 0.972 - Mlig455_003131 {REF} {Length: 1831} {RNA1509_26624, RNA1509_27545, RNA1509_31759, RNA1509_3524, RNA1509_42258, RNA1509_44854} {RNA1310_10649.1, RNA1509_26624, RNA1509_27545, RNA1509_31759, RNA1509_42258, RNA1509_44854} {RNA1509_26624, RNA1509_27545, RNA1509_31759, RNA1509_42258, RNA1509_44854, RNA815_4791.2}
26. MligTC455_30436 247 5.16 Mlig455_005917, Mlig455_007902, Mlig455_028139

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.855

 1.671 0.952 - - - 0.719 -

Mlig455_005917 {REF} {Length: 1826} {RNA1509_50227} {RNA1310_7741.2} {RNA815_2064.1}

Mlig455_007902 {REF} {Length: 6338} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=29.0]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=27.9]} {RNA1509_25737} {RNA1310_2048} {RNA815_551.1}

Mlig455_028139 {REF} {Length: 2097} {RNA1509_50227} {RNA1310_7741.2} {RNA815_2064.1}
27. MligTC455_33669 92 1.91 Mlig455_019543

Neo: -

Age: Down-Up-Down

 1.665 0.715 - - - 0.950 - Mlig455_019543 {REF} {Length: 4862} {Pfam: AAA domain [PF13401.8, score=19.5]} {RNA1310_23871} {RNA815_15612}
28. MligTC455_44180 259 5.39 Mlig455_037643

Neo: -

Age: -

 TRIM3 1.662 0.960 - - - 0.702 - Mlig455_037643 {REF} {Length: 2363} {Pfam: Ring finger domain [PF13639.8, score=26.1]; RING-type zinc-finger [PF13445.8, score=24.5]; Prokaryotic RING finger family 4 [PF14447.8, score=22.8]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=22.5]; zinc finger of C3HC4-type, RING [PF15227.8, score=22.4]; zinc-RING finger domain [PF14634.8, score=22.1]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=21.4]; RING-H2 zinc finger domain [PF12678.9, score=19.8]} {Human: ENSG00000110171, TRIM3, tripartite motif containing 3, [Score=55.8, Expect=2e-07]} {Mouse: ENSMUSG00000036989, Trim3, tripartite motif-containing 3, [Score=55.1, Expect=2e-07]} {Celegans: WBGene00003597, nhl-1, RING finger protein nhl-1, [Score=48.5, Expect=1e-05]} {Smed: dd_Smed_v6_2039_0_1, dd_Smed_v6_2039_0_1, [Score=155, Expect=6e-41]} {RNA1509_28145} {RNA1310_10684, RNA1509_28145} {RNA1509_28145, RNA815_4887}
29. MligTC455_52029 1723 35.89 Mlig455_000356

Neo: -

Age: Down-Up-Up

 DLL1 1.655 - 0.705 - - 0.950 - Mlig455_000356 {REF} {Length: 2514} {TRANSSPLICED} {Pfam: EGF-like domain [PF00008.29, score=87.1]; Human growth factor-like EGF [PF12661.9, score=49.5]; Delta serrate ligand [PF01414.21, score=48.8]; Calcium-binding EGF domain [PF07645.17, score=26.3]; EGF domain [PF12947.9, score=19.4]} {Human: ENSG00000275555, DLL1, delta like canonical Notch ligand 1, [Score=171, Expect=8e-45]; ENSG00000198719, DLL1, delta like canonical Notch ligand 1, [Score=171, Expect=8e-45]; ENSG00000128917, DLL4, delta like canonical Notch ligand 4, [Score=169, Expect=2e-44]; ENSG00000134376, CRB1, crumbs 1, cell polarity complex component, [Score=167, Expect=6e-43]} {Mouse: ENSMUSG00000014773, Dll1, delta like canonical Notch ligand 1, [Score=172, Expect=2e-45]; ENSMUSG00000027276, Jag1, jagged 1, [Score=167, Expect=5e-43]; ENSMUSG00000027878, Notch2, notch 2, [Score=165, Expect=3e-42]; ENSMUSG00000027314, Dll4, delta like canonical Notch ligand 4, [Score=164, Expect=1e-42]; ENSMUSG00000035403, Crb2, crumbs family member 2, [Score=164, Expect=4e-42]; ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=164, Expect=4e-42]} {Dmel: FBgn0004647, N, Notch, [Score=174, Expect=1e-45]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=137, Expect=2e-33]} {Smed: dd_Smed_v6_11876_0_1, dd_Smed_v6_11876_0_1, [Score=148, Expect=4e-37]} {RNA1509_42642, RNA1509_9673} {RNA1310_6973.1, RNA1509_42642, RNA1509_9673} {RNA1509_42642, RNA1509_9673, RNA815_2635.1}
30. MligTC455_34896 906 18.87 Mlig455_041044, Mlig455_070071

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.259

Region-enriched R2: 2.266/0.02183

 0.989 - - - - 0.989 -

Mlig455_041044 {REF} {Length: 7002} {TRANSSPLICED} {Pfam: Fibronectin type III domain [PF00041.23, score=34.4]; Scramblase [PF03803.17, score=18.5]} {Smed: dd_Smed_v6_66647_0_1, dd_Smed_v6_66647_0_1, [Score=113, Expect=8e-28]} {RNA1509_18182} {RNA1310_652.1} {RNA815_333}

Mlig455_070071 {REF} {Length: 6980} {TRANSSPLICED} {Pfam: Fibronectin type III domain [PF00041.23, score=34.6]; Scramblase [PF03803.17, score=18.4]} {Smed: dd_Smed_v6_66647_0_1, dd_Smed_v6_66647_0_1, [Score=113, Expect=8e-28]} {RNA1509_18182} {RNA1310_652.1} {RNA815_333}
31. MligTC455_49490 48 1 Mlig455_054769

Neo: -

Age: -

 0.986 - - - - 0.986 - Mlig455_054769 {REF} {Length: 1663} {RNA1509_22234} {RNA1310_23973} {RNA815_10832}
32. MligTC455_26255 126 2.63 Mlig455_053706

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.424/0.00107
Region-enriched R4: 3.360/0.04239

 FZD5 0.983 - - - - 0.983 - Mlig455_053706 {REF} {Length: 3671} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=393.1]; Fz domain [PF01392.24, score=105.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [RH, Score=607, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=600, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [RH, Score=562, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [RH, Score=412, Expect=5e-137]} {Smed: dd_Smed_v6_11823_0_1, dd_Smed_v6_11823_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_49831} {RNA1310_28187, RNA1509_49831} {RNA1509_49831, RNA815_16996}
33. MligTC455_30359 25 0.52 Mlig455_034159, Mlig455_040388, Mlig455_040395

Neo: -

Age: -

 ANK1, ANK2 0.983 - - - - 0.983 -

Mlig455_034159 {REF} {Length: 4637} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=167.8]; Ankyrin repeats (3 copies) [PF12796.9, score=163.2]; Ankyrin repeats (many copies) [PF13857.8, score=136.7]; Ankyrin repeat [PF13606.8, score=89.1]; Ankyrin repeat [PF00023.32, score=76.0]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=127, Expect=1e-29]} {Mouse: ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=117, Expect=5e-27]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=114, Expect=5e-26]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=114, Expect=1e-25]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=111, Expect=3e-25]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=97.1, Expect=1e-20]} {Smed: dd_Smed_v6_3523_0_1, dd_Smed_v6_3523_0_1, [Score=112, Expect=9e-26]} {RNA1509_14877} {RNA1310_782} {RNA815_17499.1}

Mlig455_040388 {REF} {Length: 4885} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=344.5]; Ankyrin repeats (many copies) [PF13637.8, score=308.8]; Ankyrin repeats (many copies) [PF13857.8, score=211.6]; Ankyrin repeat [PF13606.8, score=182.1]; Ankyrin repeat [PF00023.32, score=138.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=176, Expect=2e-44]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=174, Expect=7e-44]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=174, Expect=1e-43]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=144, Expect=7e-35]} {Smed: dd_Smed_v6_5303_0_1, dd_Smed_v6_5303_0_1, [Score=166, Expect=4e-42]} {RNA1310_90340}

Mlig455_040395 {REF} {Length: 3479} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=230.6]; Ankyrin repeats (many copies) [PF13637.8, score=193.2]; Ankyrin repeats (many copies) [PF13857.8, score=172.1]; Ankyrin repeat [PF00023.32, score=145.1]; Ankyrin repeat [PF13606.8, score=142.0]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=161, Expect=2e-40]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=160, Expect=4e-40]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=159, Expect=7e-40]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=150, Expect=2e-37]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=110, Expect=2e-24]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=169, Expect=1e-43]} {RNA1310_101625}
34. MligTC455_32311 54 1.12 Mlig455_026929

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.612

Region-enriched R2: 7.331/0.00256

 0.982 - - - - 0.982 - Mlig455_026929 {REF} {Length: 1796} {Pfam: PAN domain [PF00024.28, score=22.2]} {RNA1310_30037.1} {RNA815_37290}
35. MligTC455_44646 193 4.01 Mlig455_013515

Neo: -

Age: Down-Up-Down

 SCNN1B 0.982 - - - - 0.982 - Mlig455_013515 {REF} {Length: 2272} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=308.7]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [RH, Score=191, Expect=3e-52]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [RH, Score=188, Expect=3e-51]} {Dmel: FBgn0030795, ppk28, pickpocket 28, [Score=68.2, Expect=1e-11]} {Celegans: WBGene00012137, asic-2, Degenerin-like protein asic-2, [Score=143, Expect=2e-36]} {Smed: dd_Smed_v6_17021_0_1, dd_Smed_v6_17021_0_1, [Score=175, Expect=2e-47]} {RNA1509_52917} {RNA1310_12013.1, RNA1509_52917} {RNA1509_52917, RNA815_4777}
36. MligTC455_45495 988 20.58 Mlig455_010003

Neo: -

Age: logFC(26M/2M)=0.384

Region-enriched R2: 2.517/0.00003

 CAV2 0.981 - - - - 0.981 - Mlig455_010003 {REF} {Length: 748} {Pfam: Caveolin [PF01146.19, score=125.0]} {Human: ENSG00000105971, CAV2, caveolin 2, [Score=85.5, Expect=3e-21]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [Score=89.4, Expect=7e-23]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=79.0, Expect=2e-18]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=153, Expect=1e-48]} {RNA1509_20287} {RNA1310_50581.1} {RNA815_31873}
37. MligTC455_15661 322 6.72 Mlig455_000589

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.500/0.00231

 NR2E1 0.98 - - - - 0.980 - Mlig455_000589 {REF} {Length: 2434} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=97.6]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=73.9]} {Human: ENSG00000112333, NR2E1, nuclear receptor subfamily 2 group E member 1, [Score=188, Expect=2e-53]} {Mouse: ENSMUSG00000019803, Nr2e1, nuclear receptor subfamily 2, group E, member 1, [Score=188, Expect=1e-53]} {Dmel: FBgn0003720, tll, tailless, [RH, Score=202, Expect=2e-58]} {Celegans: WBGene00003657, nhr-67, Nuclear hormone receptor family member nhr-67, [RH, Score=193, Expect=3e-55]} {Smed: dd_Smed_v6_21347_0_1, dd_Smed_v6_21347_0_1, [RH, Score=188, Expect=9e-54]} {RNA1509_39776} {RNA1310_21550, RNA1509_39776} {RNA1509_39776, RNA815_27099.1}
38. MligTC455_19322 47 0.98 Mlig455_060292

Neo: -

Age: -

Region-enriched R5: 4.828/0.04092

 0.98 - - - - 0.980 - Mlig455_060292 {REF} {Length: 1265} {RNA1310_61465} {RNA815_19768}
39. MligTC455_31862 185 3.86 Mlig455_010898

Neo: -

Age: Up-Down-Down

 HCRTR1 0.98 - - - - 0.980 - Mlig455_010898 {REF} {Length: 3607} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=152.1]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=28.5]} {Human: ENSG00000121764, HCRTR1, hypocretin receptor 1, [Score=100, Expect=2e-22]; ENSG00000110148, CCKBR, cholecystokinin B receptor, [Score=100, Expect=2e-22]; ENSG00000186867, QRFPR, pyroglutamylated RFamide peptide receptor, [Score=96.3, Expect=4e-21]; ENSG00000163394, CCKAR, cholecystokinin A receptor, [Score=96.3, Expect=4e-21]; ENSG00000162009, SSTR5, somatostatin receptor 5, [Score=95.9, Expect=3e-21]} {Mouse: ENSMUSG00000028778, Hcrtr1, hypocretin (orexin) receptor 1, [Score=108, Expect=1e-25]} {Dmel: FBgn0038880, SIFaR, SIFamide receptor, [Score=95.5, Expect=9e-21]} {Celegans: WBGene00013187, npr-34, NeuroPeptide Receptor family, [RH, Score=131, Expect=7e-33]} {Smed: dd_Smed_v6_56182_0_1, dd_Smed_v6_56182_0_1, [Score=135, Expect=2e-37]} {RNA1509_56148} {RNA1310_5450.1} {RNA815_7136.1}
40. MligTC455_33807 5328 111 Mlig455_009549

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.374

 MOXD1 0.98 - - - - 0.980 - Mlig455_009549 {REF} {Length: 2314} {TRANSSPLICED} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=92.6]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=67.9]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=120, Expect=4e-28]; ENSG00000123454, DBH, dopamine beta-hydroxylase, [Score=117, Expect=6e-27]} {Mouse: ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=135, Expect=4e-33]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=127, Expect=1e-30]} {Celegans: WBGene00006541, tbh-1, Tyramine beta-hydroxylase, [Score=137, Expect=3e-34]} {Smed: dd_Smed_v6_42610_0_1, dd_Smed_v6_42610_0_1, [Score=117, Expect=1e-28]} {RNA1509_127, RNA1509_16513, RNA1509_19891, RNA1509_42226} {RNA1310_10830.1, RNA1509_127, RNA1509_16513, RNA1509_19891, RNA1509_42226} {RNA1509_127, RNA1509_16513, RNA1509_19891, RNA1509_42226, RNA815_4383.2}
41. MligTC455_35894 23 0.48 Mlig455_029906

Neo: -

Age: -

 RYK 0.98 - - - - 0.980 - Mlig455_029906 {REF} {Length: 3571} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=210.1]; WIF domain [PF02019.20, score=110.2]; Protein kinase domain [PF00069.27, score=79.8]} {Human: ENSG00000163785, RYK, receptor-like tyrosine kinase, [Score=202, Expect=7e-57]} {Mouse: ENSMUSG00000032547, Ryk, receptor-like tyrosine kinase, [Score=202, Expect=9e-57]} {Dmel: FBgn0015380, drl, derailed, [RH, Score=241, Expect=7e-71]} {Celegans: WBGene00003007, lin-18, Inactive tyrosine-protein kinase RYK, [RH, Score=179, Expect=9e-49]} {Smed: dd_Smed_v6_12594_0_3, dd_Smed_v6_12594_0_3, [Score=201, Expect=2e-56]} {RNA1509_58811} {RNA1310_6671.2, RNA1509_58811} {RNA1509_58811, RNA815_41921}
42. MligTC455_43690 262 5.46 Mlig455_035029, Mlig455_053437

Neo: -

Age: -

Region-enriched R2: 6.108/0.00708

 WSCD2 0.98 - - - - 0.980 -

Mlig455_035029 {REF} {Length: 893} {Pfam: WSC domain [PF01822.21, score=50.2]; PAN domain [PF00024.28, score=29.7]} {RNA1310_42429} {RNA815_24291.1}

Mlig455_053437 {REF} {Length: 972} {Pfam: WSC domain [PF01822.21, score=52.4]; PAN domain [PF00024.28, score=29.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=44.7, Expect=1e-05]} {RNA1310_42429} {RNA815_24291.1}
43. MligTC455_21435 37 0.77 Mlig455_016499

Neo: -

Age: -

 RTL1 0.979 - - - - 0.979 - Mlig455_016499 {REF} {Length: 4412} {TRANSSPLICED} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=104.0]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=88.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=79.5]} {Human: ENSG00000254656, RTL1, retrotransposon Gag like 1, [Score=109, Expect=7e-24]} {Smed: dd_Smed_v6_1574_6_44, dd_Smed_v6_1574_6_44, [Score=278, Expect=5e-84]} {RNA1509_56816} {RNA1310_8523, RNA1509_56816}
44. MligTC455_29204 333 6.93 Mlig455_052247

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.586

 ANK3 0.979 - - - - 0.979 - Mlig455_052247 {REF} {Length: 5485} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=62.8]; Ankyrin repeats (many copies) [PF13637.8, score=51.6]; Ankyrin repeat [PF00023.32, score=40.1]; Ankyrin repeat [PF13606.8, score=38.1]; Ankyrin repeats (many copies) [PF13857.8, score=34.4]; Mab-21 protein [PF03281.16, score=20.6]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=65.9, Expect=3e-10]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=65.9, Expect=2e-10]} {Dmel: FBgn0031473, CG3104, [Score=74.3, Expect=6e-14]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=58.2, Expect=2e-08]} {Smed: dd_Smed_v6_9936_0_1, dd_Smed_v6_9936_0_1, [Score=70.5, Expect=2e-12]} {RNA1509_39688} {RNA1310_6142.1} {RNA815_6750.1}
45. MligTC455_43581 177 3.68 Mlig455_042725, Mlig455_042827, Mlig455_063146

Neo: -

Age: Up-Down-Down

 GRIA2 0.979 - - - - 0.979 -

Mlig455_042725 {REF} {Length: 3074} {Pfam: Ligand-gated ion channel [PF00060.28, score=104.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.7]; Receptor family ligand binding region [PF01094.30, score=33.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=153, Expect=1e-37]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=149, Expect=2e-36]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=147, Expect=7e-36]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=152, Expect=2e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=148, Expect=3e-36]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=147, Expect=8e-36]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=2e-35]} {Dmel: FBgn0038837, CG3822, [Score=140, Expect=5e-34]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=253, Expect=2e-76]} {RNA1310_25150} {RNA815_13942}

Mlig455_042827 {REF} {Length: 2869} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.9]; Receptor family ligand binding region [PF01094.30, score=49.8]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.3]; Iron-containing alcohol dehydrogenase [PF13685.8, score=18.6]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=125, Expect=6e-29]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=122, Expect=5e-28]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=121, Expect=7e-28]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=120, Expect=2e-27]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=125, Expect=5e-29]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=122, Expect=4e-28]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=121, Expect=1e-27]; ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=120, Expect=1e-27]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=119, Expect=3e-27]} {Dmel: FBgn0039927, CG11155, [Score=127, Expect=7e-30]} {Celegans: WBGene00001612, glr-1, Glutamate receptor 1, [Score=103, Expect=1e-22]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=217, Expect=2e-63]} {RNA1310_25150} {RNA815_13942}

Mlig455_063146 {REF} {Length: 2444} {Pfam: Receptor family ligand binding region [PF01094.30, score=35.8]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=82.4, Expect=1e-16]} {RNA1310_25150} {RNA815_13999}
46. MligTC455_46956 548 11.42 Mlig455_033544

Neo: -

Age: Down-Up-Up

Region-enriched R6: 2.145/0.00606

 0.979 - - - - 0.979 - Mlig455_033544 {REF} {Length: 1097} {RNA1509_43580} {RNA1310_52830, RNA1509_43580} {RNA1509_43580, RNA815_30284}
47. MligTC455_12846 29 0.6 Mlig455_064694

Neo: -

Age: -

 0.978 - - - - 0.978 - Mlig455_064694 {REF} {Length: 967} {NoTransDecoderORF} {RNA1310_110650}
48. MligTC455_24271 22 0.45 Mlig455_005190

Neo: -

Age: -

 0.978 - - - - 0.978 - Mlig455_005190 {REF} {Length: 600} {RNA1509_43533} {RNA1310_100097} {RNA815_22406}
49. MligTC455_25464 185 3.85 Mlig455_001339

Neo: -

Age: -

Region-enriched R2: 4.725/0.00025

 0.978 - - - - 0.978 - Mlig455_001339 {REF} {Length: 1386} {RNA1509_58508} {RNA1310_32754, RNA1509_58508} {RNA1509_58508, RNA815_47065}
50. MligTC455_29203 334 6.95 Mlig455_037140

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.614

 0.978 - - - - 0.978 - Mlig455_037140 {REF} {Length: 5032} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=37.3]; Ankyrin repeat [PF00023.32, score=28.8]; Ankyrin repeat [PF13606.8, score=25.8]; Ankyrin repeats (many copies) [PF13637.8, score=24.6]; Ankyrin repeats (many copies) [PF13857.8, score=22.2]; Mab-21 protein [PF03281.16, score=20.5]} {RNA1509_39416} {RNA1310_14401} {RNA815_5545.1}
51. MligTC455_35828 388 8.08 Mlig455_052310

Neo: -

Age: -

Region-enriched R8: 1.759/0.04106

 AJM1 0.978 - - - - 0.978 - Mlig455_052310 {REF} {Length: 6864} {Pfam: MYND finger [PF01753.20, score=19.7]} {Human: ENSG00000232434, AJM1, apical junction component 1 homolog, [Score=73.9, Expect=3e-12]} {Mouse: ENSMUSG00000029419, Ajm1, apical junction component 1, [Score=78.2, Expect=8e-14]} {Dmel: FBgn0261802, CG42748, [Score=62.4, Expect=4e-09]} {RNA1509_7980} {RNA1310_3656} {RNA815_1390}
52. MligTC455_37792 210 4.38 Mlig455_024774

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.926

Region-enriched R2: 6.055/0.00271

 PKD1L2 0.978 - - - - 0.978 - Mlig455_024774 {REF} {Length: 6374} {Pfam: Polycystin cation channel [PF08016.14, score=224.6]; PLAT/LH2 domain [PF01477.25, score=66.8]; Ion transport protein [PF00520.33, score=30.8]} {Human: ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [Score=179, Expect=9e-45]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=187, Expect=3e-47]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=109, Expect=1e-23]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=187, Expect=2e-47]} {Smed: dd_Smed_v6_13975_0_1, dd_Smed_v6_13975_0_1, [Score=902, Expect=0.0]} {RNA1509_46134} {RNA1310_488} {RNA815_1711}
53. MligTC455_40352 49 1.03 Mlig455_024410

Neo: -

Age: -

 0.978 - - - - 0.978 - Mlig455_024410 {REF} {Length: 1509} {TRANSSPLICED} {RNA1310_29008} {RNA815_41596}
54. MligTC455_49763 130 2.72 Mlig455_006404

Neo: -

Age: -

Region-enriched R2: 3.029/0.02346

 KREMEN1 0.978 - - - - 0.978 - Mlig455_006404 {REF} {Length: 1879} {Pfam: WSC domain [PF01822.21, score=53.7]; PAN domain [PF00024.28, score=24.0]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=45.1, Expect=1e-05]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=44.7, Expect=1e-05]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=47.8, Expect=9e-07]} {RNA1509_53783} {RNA1310_43597} {RNA815_9084.2}
55. MligTC455_07087 753 15.69 Mlig455_033003, Mlig455_044987, Mlig455_044989, Mlig455_052687

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.952

 0.977 0.977 - - - - -

Mlig455_033003 {REF} {Length: 253} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944} {RNA815_10907}

Mlig455_044987 {REF} {Length: 249} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944, RNA1509_51459} {RNA1509_51459, RNA815_10907}

Mlig455_044989 {REF} {Length: 239} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944} {RNA815_10907}

Mlig455_052687 {REF} {Length: 243} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944} {RNA815_10907}
56. MligTC455_08103 8 0.16 Mlig455_056829

Neo: -

Age: -

 0.976 - - - - 0.976 - Mlig455_056829 {REF} {Length: 754} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_24771} {RNA1310_8080} {RNA815_26991}
57. MligTC455_11123 37 0.77 Mlig455_032334

Neo: -

Age: Down-Up-Up

 0.976 - - - - 0.976 - Mlig455_032334 {REF} {Length: 4865} {Pfam: PAS domain [PF13188.9, score=19.3]} {RNA1509_56926} {RNA1310_51110.1} {RNA815_20842.1}
58. MligTC455_11229 51 1.06 Mlig455_054212

Neo: -

Age: -

 0.976 - - - - 0.976 - Mlig455_054212 {REF} {Length: 1481} {RNA1310_23944} {RNA815_32018}
59. MligTC455_13171 25 0.53 Mlig455_005963, Mlig455_005967

Neo: -

Age: -

 0.976 - - - - 0.976 -

Mlig455_005963 {REF} {Length: 2617} {RNA1509_20946} {RNA1310_146331} {RNA815_35450}

Mlig455_005967 {REF} {Length: 1405} {Pfam: Lectin C-type domain [PF00059.23, score=20.7]} {RNA1509_20946} {RNA1310_146331} {RNA815_35450}
60. MligTC455_14955 12 0.25 Mlig455_058159

Neo: -

Age: -

 0.976 - - - - 0.976 - Mlig455_058159 {REF} {Length: 510} {NoTransDecoderORF} {RNA1310_122094}
61. MligTC455_17412 44 0.91 Mlig455_069737

Neo: -

Age: -

Region-enriched R2: 5.062/0.00923

 0.976 - - - - 0.976 - Mlig455_069737 {REF} {Length: 1628} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=42.8]} {Smed: dd_Smed_v6_31564_0_1, dd_Smed_v6_31564_0_1, [Score=72.8, Expect=3e-14]} {RNA1310_45758} {RNA815_42912}
62. MligTC455_18322 82 1.71 Mlig455_021228

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.636

 0.976 - - - - 0.976 - Mlig455_021228 {REF} {Length: 3954} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=26.3]} {Smed: dd_Smed_v6_11972_0_1, dd_Smed_v6_11972_0_1, [RH, Score=229, Expect=2e-64]} {RNA1509_9124} {RNA1310_5268.1, RNA1509_9124} {RNA1509_9124, RNA815_1717.1}
63. MligTC455_22446 195 4.05 Mlig455_002759, Mlig455_063362

Neo: -

Age: -

Region-enriched R2: 4.960/0.00023

 SLC6A3 0.976 - - - - 0.976 -

Mlig455_002759 {REF} {Length: 4906} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=606.3]; Rhomboid family [PF01694.24, score=73.2]} {Human: ENSG00000276996, SLC6A3, solute carrier family 6 member 3, [Score=541, Expect=9e-179]; ENSG00000142319, SLC6A3, solute carrier family 6 member 3, [Score=541, Expect=9e-179]; ENSG00000103546, SLC6A2, solute carrier family 6 member 2, [Score=540, Expect=3e-178]} {Mouse: ENSMUSG00000055368, Slc6a2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, [Score=552, Expect=0.0]; ENSMUSG00000021609, Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, [Score=545, Expect=3e-180]} {Dmel: FBgn0034136, DAT, Dopamine transporter, [Score=498, Expect=2e-162]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=446, Expect=9e-143]} {Smed: dd_Smed_v6_22486_0_1, dd_Smed_v6_22486_0_1, [RH, Score=605, Expect=0.0]} {RNA1509_46048} {RNA1310_21784} {RNA815_8613}

Mlig455_063362 {REF} {Length: 2875} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=603.8]} {Human: ENSG00000276996, SLC6A3, solute carrier family 6 member 3, [Score=543, Expect=0.0]; ENSG00000142319, SLC6A3, solute carrier family 6 member 3, [Score=543, Expect=0.0]; ENSG00000103546, SLC6A2, solute carrier family 6 member 2, [Score=540, Expect=0.0]} {Mouse: ENSMUSG00000055368, Slc6a2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, [Score=551, Expect=0.0]; ENSMUSG00000021609, Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, [Score=549, Expect=0.0]} {Dmel: FBgn0034136, DAT, Dopamine transporter, [Score=494, Expect=4e-167]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=444, Expect=7e-148]} {Smed: dd_Smed_v6_22486_0_1, dd_Smed_v6_22486_0_1, [RH, Score=599, Expect=0.0]} {RNA1509_46048} {RNA1310_21784} {RNA815_8613}
64. MligTC455_23082 1608 33.5 Mlig455_024173

Neo: -

Age: -

 FAT4 0.976 - - - - 0.976 - Mlig455_024173 {REF} {Length: 8284} {Pfam: Cadherin domain [PF00028.19, score=731.9]; Cadherin-like [PF16184.7, score=111.8]; Cadherin-like [PF08266.14, score=26.5]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=544, Expect=2e-155]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=514, Expect=2e-146]} {Dmel: FBgn0284247, ds, dachsous, [Score=463, Expect=8e-131]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=276, Expect=4e-74]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=279, Expect=7e-75]} {RNA1509_848} {RNA1310_296} {RNA815_105}
65. MligTC455_29543 94 1.96 Mlig455_066835

Neo: -

Age: Down-Down-Up

Region-enriched R2: 3.991/0.02759

 PGBD4 0.976 - - - - 0.976 - Mlig455_066835 {REF} {Length: 7088} {Pfam: Transposase IS4 [PF13843.8, score=213.7]} {Human: ENSG00000182405, PGBD4, piggyBac transposable element derived 4, [RH, Score=206, Expect=4e-59]} {Mouse: ENSMUSG00000050751, Pgbd5, piggyBac transposable element derived 5, [RH, Score=74.3, Expect=1e-13]} {Dmel: FBgn0037633, CG9839, [RH, Score=96.3, Expect=7e-21]} {Smed: dd_Smed_v6_48522_0_1, dd_Smed_v6_48522_0_1, [RH, Score=116, Expect=1e-29]} {RNA1509_18157} {RNA1310_616.1} {RNA815_9301.1}
66. MligTC455_41517 18 0.37 Mlig455_018289

Neo: -

Age: -

 0.976 - - - - 0.976 - Mlig455_018289 {REF} {Length: 3393} {TRANSSPLICED} {RNA1509_58315} {RNA1310_24815} {RNA815_16210}
67. MligTC455_48634 30 0.62 Mlig455_006052, Mlig455_068060

Neo: -

Age: -

 ANGPTL4, FCN2 0.976 - - - - 0.976 -

Mlig455_006052 {REF} {Length: 2091} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=64.0]} {Human: ENSG00000160339, FCN2, ficolin 2, [Score=83.6, Expect=2e-17]} {Mouse: ENSMUSG00000042436, Mfap4, microfibrillar-associated protein 4, [Score=71.6, Expect=9e-14]} {Dmel: FBgn0034160, CG5550, [Score=67.4, Expect=2e-12]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=62.0, Expect=2e-10]} {RNA1310_118683}

Mlig455_068060 {REF} {Length: 1573} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=43.6]} {Human: ENSG00000167772, ANGPTL4, angiopoietin like 4, [Score=53.9, Expect=9e-08]} {Mouse: ENSMUSG00000028553, Angptl3, angiopoietin-like 3, [Score=50.4, Expect=9e-07]} {Dmel: FBgn0050280, CG30280, [Score=57.0, Expect=2e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=53.9, Expect=3e-08]} {RNA1310_87835}
68. MligTC455_49958 16 0.32 Mlig455_014437, Mlig455_070189

Neo: -

Age: -

 0.976 - - - - 0.976 -

Mlig455_014437 {REF} {Length: 921} {RNA1310_45206} {RNA815_28788}

Mlig455_070189 {REF} {Length: 739} {RNA1310_45206} {RNA815_28788}
69. MligTC455_50344 24 0.51 Mlig455_054355

Neo: -

Age: -

 0.976 - - - - 0.976 - Mlig455_054355 {REF} {Length: 1376} {RNA1310_56750}
70. MligTC455_52232 92 1.92 Mlig455_007894, Mlig455_008001

Neo: -

Age: logFC(26M/2M)=0.549

 0.976 - - - - 0.976 -

Mlig455_007894 {REF} {Length: 1500} {RNA1310_22136} {RNA815_18832}

Mlig455_008001 {REF} {Length: 1450} {Pfam: PAN domain [PF00024.28, score=18.9]} {RNA1310_22136} {RNA815_18832}
71. MligTC455_56570 7 0.15 Mlig455_001073

Neo: -

Age: -

 0.976 - - - - 0.976 - Mlig455_001073 {REF} {Length: 237} {NoTransDecoderORF} {RNA1509_2515} {RNA1310_92588} {RNA815_36493}
72. MligTC455_56698 6 0.12 Mlig455_025020

Neo: -

Age: -

 KIAA1958 0.976 - - - - 0.976 - Mlig455_025020 {REF} {Length: 662} {Pfam: Domain of unknown function (DUF3504) [PF12012.10, score=44.7]; Phage integrase family [PF00589.24, score=39.5]} {Human: ENSG00000165185, KIAA1958, KIAA1958, [Score=50.8, Expect=6e-07]} {Mouse: ENSMUSG00000045071, E130308A19Rik, RIKEN cDNA E130308A19 gene, [Score=50.8, Expect=4e-07]} {RNA1310_51564}
73. MligTC455_10218 4 0.08 Mlig455_048460

Neo: -

Age: -

 0.975 - - - - 0.975 - Mlig455_048460 {REF} {Length: 476} {NoTransDecoderORF}
74. MligTC455_14565 555 11.56 Mlig455_025146

Neo: -

Age: -

 0.975 0.975 - - - - - Mlig455_025146 {REF} {Length: 2733} {TRANSSPLICED} {RNA1509_11357} {RNA1310_10080.1, RNA1509_11357} {RNA1509_11357, RNA815_13917}
75. MligTC455_18323 168 3.5 Mlig455_021183, Mlig455_057885

Neo: -

Age: logFC(26M/2M)=-0.384

Region-enriched R2: 3.394/0.02680

 0.975 - - - - 0.975 -

Mlig455_021183 {REF} {Length: 3969} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=24.3]} {Smed: dd_Smed_v6_11972_0_1, dd_Smed_v6_11972_0_1, [RH, Score=221, Expect=7e-62]} {RNA1509_9124} {RNA1310_5268.1} {RNA815_1717.1}

Mlig455_057885 {REF} {Length: 4416} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=24.3]} {Smed: dd_Smed_v6_11972_0_1, dd_Smed_v6_11972_0_1, [RH, Score=221, Expect=1e-61]} {RNA1509_9124} {RNA1310_5268.1} {RNA815_1717.1}
76. MligTC455_23640 29 0.6 Mlig455_067288

Neo: -

Age: -

 0.975 - - - - 0.975 - Mlig455_067288 {REF} {Length: 820} {RNA1310_58177} {RNA815_30723}
77. MligTC455_24829 258 5.39 Mlig455_001260

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.723

 CCDC80 0.975 - - - - 0.975 - Mlig455_001260 {REF} {Length: 10454} {Human: ENSG00000091986, CCDC80, coiled-coil domain containing 80, [Score=52.8, Expect=1e-05]} {Dmel: FBgn0053196, dpy, dumpy, [Score=52.4, Expect=9e-06]} {RNA1509_23601} {RNA1310_241} {RNA815_110.1}
78. MligTC455_25858 48 1 Mlig455_005649, Mlig455_005698, Mlig455_008659

Neo: -

Age: -

 0.975 - - - - 0.975 -

Mlig455_005649 {REF} {Length: 1060} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=27.0]} {RNA1509_35414} {RNA1310_2501.1} {RNA815_9496.1}

Mlig455_005698 {REF} {Length: 1505} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=26.8]} {RNA1509_35414} {RNA1310_2501.1} {RNA815_9496.1}

Mlig455_008659 {REF} {Length: 1151} {TRANSSPLICED} {Pfam: haloacid dehalogenase-like hydrolase [PF08282.14, score=19.9]} {RNA1509_25258} {RNA1310_56236} {RNA815_9496.1}
79. MligTC455_33495 28 0.58 Mlig455_047292, Mlig455_047342, Mlig455_069323

Neo: -

Age: -

 LHFPL2 0.975 - - - - 0.975 -

Mlig455_047292 {REF} {Length: 1105} {RNA1310_118047}

Mlig455_047342 {REF} {Length: 1735} {Pfam: Lipoma HMGIC fusion partner-like protein [PF10242.11, score=104.8]; PMP-22/EMP/MP20/Claudin tight junction [PF13903.8, score=30.7]} {Human: ENSG00000145685, LHFPL2, LHFPL tetraspan subfamily member 2, [Score=47.8, Expect=1e-05]} {Mouse: ENSMUSG00000045312, Lhfpl2, lipoma HMGIC fusion partner-like 2, [Score=47.0, Expect=1e-05]} {Smed: dd_Smed_v6_9373_0_1, dd_Smed_v6_9373_0_1, [Score=175, Expect=1e-51]} {RNA1509_30020} {RNA1310_118047} {RNA815_5159.1}

Mlig455_069323 {REF} {Length: 886} {RNA1310_118047}
80. MligTC455_39096 110 2.29 Mlig455_019781, Mlig455_019803

Neo: -

Age: -

 0.975 - - - - 0.975 -

Mlig455_019781 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=65.0]} {RNA1310_34740} {RNA815_15663}

Mlig455_019803 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.1]} {RNA1310_34740} {RNA815_15663}
81. MligTC455_43885 14 0.3 Mlig455_060361

Neo: -

Age: -

 0.975 - - - - 0.975 - Mlig455_060361 {REF} {Length: 1022} {NoTransDecoderORF} {RNA1310_68891}
82. MligTC455_51658 123 2.56 Mlig455_028791

Neo: -

Age: Down-Up-Down

 0.975 0.975 - - - - - Mlig455_028791 {REF} {Length: 2943} {TRANSSPLICED} {Pfam: F-box-like [PF12937.9, score=22.8]} {RNA1509_58492} {RNA1310_6222.1, RNA1509_58492} {RNA1509_58492, RNA815_11096}
83. MligTC455_10674 457 9.51 Mlig455_033481

Neo: -

Age: Down-Up-Down

 0.974 0.974 - - - - - Mlig455_033481 {REF} {Length: 2182} {Smed: dd_Smed_v6_5091_0_1, dd_Smed_v6_5091_0_1, [RH, Score=154, Expect=1e-45]} {RNA1509_8208} {RNA1310_11510} {RNA815_4269}
84. MligTC455_17088 56 1.16 Mlig455_022778

Neo: -

Age: logFC(26M/2M)=-0.737

 0.974 - - - - 0.974 - Mlig455_022778 {REF} {Length: 2080} {RNA1509_56619} {RNA1310_21133.1} {RNA815_8631.1}
85. MligTC455_18911 10 0.21 Mlig455_003995

Neo: -

Age: -

 0.974 - - - - 0.974 - Mlig455_003995 {REF} {Length: 1473} {Pfam: F5/8 type C domain [PF00754.27, score=28.7]} {RNA1509_32267} {RNA1310_43457} {RNA815_19080.1}
86. MligTC455_42188 714 14.88 Mlig455_004983

Neo: -

Age: -

 0.974 - - - - 0.974 - Mlig455_004983 {REF} {Length: 958} {RNA1509_36666, RNA1509_48333} {RNA1310_81420, RNA1509_36666, RNA1509_48333} {RNA1509_36666, RNA1509_48333, RNA815_25950}
87. MligTC455_42507 6 0.13 Mlig455_003287

Neo: -

Age: -

 0.974 - - - - 0.974 - Mlig455_003287 {REF} {Length: 1202} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=73.6]} {Dmel: FBgn0004841, TkR86C, Tachykinin-like receptor at 86C, [Score=48.1, Expect=7e-06]}
88. MligTC455_46869 20 0.41 Mlig455_054214

Neo: -

Age: -

 0.974 - - - - 0.974 - Mlig455_054214 {REF} {Length: 1474} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=19.0]} {RNA1310_23944} {RNA815_32018}
89. MligTC455_49671 22 0.45 Mlig455_031821, Mlig455_047620, Mlig455_047673

Neo: -

Age: -

 0.974 - - - - 0.974 -

Mlig455_031821 {REF} {Length: 954} {Pfam: WSC domain [PF01822.21, score=56.5]; PAN domain [PF00024.28, score=20.4]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=54.7, Expect=2e-08]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=53.9, Expect=2e-08]} {RNA1509_43359} {RNA1310_64325} {RNA815_23776.1}

Mlig455_047620 {REF} {Length: 1341} {Pfam: WSC domain [PF01822.21, score=54.9]; Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=21.1]; PAN domain [PF00024.28, score=19.0]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=55.8, Expect=6e-08]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=54.7, Expect=8e-08]} {RNA1509_43359} {RNA1310_64325} {RNA815_23776.1}

Mlig455_047673 {REF} {Length: 1341} {Pfam: WSC domain [PF01822.21, score=54.9]; Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=21.1]; PAN domain [PF00024.28, score=19.0]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=55.8, Expect=6e-08]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=54.7, Expect=8e-08]} {RNA1509_43359} {RNA1310_64325} {RNA815_23776.1}
90. MligTC455_50546 21 0.44 Mlig455_045408

Neo: -

Age: -

 0.974 - - - - 0.974 - Mlig455_045408 {REF} {Length: 1345} {RNA1310_102440}
91. MligTC455_52289 1304 27.17 Mlig455_040536, Mlig455_062101

Neo: -

Age: -

Region-enriched R2: 2.340/0.00741

 CDH23 0.974 - - - - 0.974 -

Mlig455_040536 {REF} {Length: 5566} {Pfam: Cadherin domain [PF00028.19, score=482.5]; Cadherin-like [PF08266.14, score=52.6]; Cadherin-like [PF16184.7, score=49.2]; RET Cadherin like domain 1 [PF17756.3, score=29.6]; Chlamydia polymorphic membrane protein middle domain [PF07548.13, score=19.7]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=405, Expect=4e-114]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=424, Expect=3e-120]} {Dmel: FBgn0036715, Cad74A, Cadherin 74A, [RH, Score=603, Expect=0.0]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=241, Expect=9e-64]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=291, Expect=2e-79]} {RNA1509_2629, RNA1509_34857} {RNA1310_891, RNA1509_2629, RNA1509_34857} {RNA1509_2629, RNA1509_34857, RNA815_261}

Mlig455_062101 {REF} {Length: 5552} {Pfam: Cadherin domain [PF00028.19, score=474.3]; Cadherin-like [PF08266.14, score=52.6]; Cadherin-like [PF16184.7, score=50.6]; RET Cadherin like domain 1 [PF17756.3, score=28.9]; Chlamydia polymorphic membrane protein middle domain [PF07548.13, score=19.5]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=417, Expect=4e-118]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=416, Expect=1e-117]} {Dmel: FBgn0036715, Cad74A, Cadherin 74A, [RH, Score=600, Expect=0.0]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=230, Expect=2e-60]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=286, Expect=6e-78]} {RNA1509_54845} {RNA1310_830, RNA1509_54845} {RNA1509_54845, RNA815_261}
92. MligTC455_11078 15 0.31 Mlig455_045628

Neo: -

Age: -

 0.973 - - - - 0.973 - Mlig455_045628 {REF} {Length: 2373} {Pfam: Polycystin cation channel [PF08016.14, score=25.4]} {RNA1310_39436.1} {RNA815_35444}
93. MligTC455_14340 69 1.44 Mlig455_043719, Mlig455_043806

Neo: -

Age: -

 PLAT 0.973 - - - - 0.973 -

Mlig455_043719 {REF} {Length: 4752} {Pfam: Kringle domain [PF00051.20, score=51.5]} {Human: ENSG00000104368, PLAT, plasminogen activator, tissue type, [Score=57.0, Expect=9e-08]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=51.6, Expect=3e-06]; ENSMUSG00000059481, Plg, plasminogen, [Score=51.2, Expect=6e-06]; ENSMUSG00000031538, Plat, plasminogen activator, tissue, [Score=50.4, Expect=7e-06]} {Dmel: FBgn0010407, Ror, [Score=51.6, Expect=3e-06]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=50.1, Expect=8e-06]} {RNA1509_21873} {RNA1310_6714.1} {RNA815_2006.1}

Mlig455_043806 {REF} {Length: 5127} {Pfam: Kringle domain [PF00051.20, score=51.5]} {Human: ENSG00000104368, PLAT, plasminogen activator, tissue type, [Score=57.0, Expect=9e-08]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=51.6, Expect=3e-06]; ENSMUSG00000059481, Plg, plasminogen, [Score=51.2, Expect=6e-06]; ENSMUSG00000031538, Plat, plasminogen activator, tissue, [Score=50.4, Expect=7e-06]} {Dmel: FBgn0010407, Ror, [Score=51.6, Expect=3e-06]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=50.1, Expect=8e-06]} {RNA1509_21873} {RNA1310_6714.1} {RNA815_2006.1}
94. MligTC455_17602 62 1.3 Mlig455_065788

Neo: -

Age: -

 0.973 - - - - 0.973 - Mlig455_065788 {REF} {Length: 1038} {NoTransDecoderORF} {RNA1509_9817} {RNA1310_14959.1} {RNA815_22311}
95. MligTC455_18969 652 13.59 Mlig455_069454

Neo: -

Age: logFC(26M/2M)=-0.427

 SPTSSA 0.973 - - - - 0.973 - Mlig455_069454 {REF} {Length: 2206} {Pfam: Small subunit of serine palmitoyltransferase-like [PF11779.10, score=31.0]} {Human: ENSG00000165389, SPTSSA, serine palmitoyltransferase small subunit A, [Score=41.6, Expect=1e-05]} {Mouse: ENSMUSG00000044408, Sptssa, serine palmitoyltransferase, small subunit A, [Score=41.2, Expect=1e-05]} {RNA1509_24576} {RNA1310_23455, RNA1509_24576} {RNA1509_24576, RNA815_21677}
96. MligTC455_19042 3679 76.64 Mlig455_030661

Neo: -

Age: logFC(26M/2M)=0.480

Region-specific R2: 2.811

Region-enriched R2: 1.755/0.00003

 CAV1 0.973 - - - - 0.973 - Mlig455_030661 {REF} {Length: 1257} {Pfam: Caveolin [PF01146.19, score=124.8]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=105, Expect=2e-29]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=105, Expect=2e-29]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=81.6, Expect=8e-20]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=144, Expect=1e-45]} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1310_31540, RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522, RNA815_14585}
97. MligTC455_24716 8 0.17 Mlig455_059952

Neo: -

Age: Down-Up-Down

 MARCH8 0.973 - - - - 0.973 - Mlig455_059952 {REF} {Length: 2107} {TRANSSPLICED} {Pfam: RING-variant domain [PF12906.9, score=56.5]} {Human: ENSG00000165406, MARCH8, membrane associated ring-CH-type finger 8, [RH, Score=226, Expect=7e-69]; ENSG00000145416, MARCH1, membrane associated ring-CH-type finger 1, [RH, Score=223, Expect=5e-68]; ENSG00000278545, MARCH8, membrane associated ring-CH-type finger 8, [RH, Score=220, Expect=3e-70]} {Mouse: ENSMUSG00000025702, March8, membrane-associated ring finger (C3HC4) 8, [RH, Score=228, Expect=4e-73]; ENSMUSG00000036469, March1, membrane-associated ring finger (C3HC4) 1, [RH, Score=226, Expect=6e-72]} {Dmel: FBgn0035983, CG4080, [RH, Score=222, Expect=5e-67]} {Celegans: WBGene00007643, marc-3, MARCH (Membrane-Associated Ring finger (C3HC4)) homolog, [RH, Score=67.8, Expect=2e-12]} {Smed: dd_Smed_v6_4997_0_2, dd_Smed_v6_4997_0_2, [RH, Score=244, Expect=7e-78]} {RNA1509_23175} {RNA1310_20001, RNA1509_23175} {RNA1509_23175, RNA815_11300}
98. MligTC455_27650 178 3.72 Mlig455_017720

Neo: -

Age: logFC(26M/2M)=-0.928

Region-enriched R2: 3.586/0.00082

 ADAM33 0.973 - - - - 0.973 - Mlig455_017720 {REF} {Length: 4499} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=124.3]; Disintegrin [PF00200.25, score=66.8]; Metallo-peptidase family M12 [PF13688.8, score=62.2]; ADAM cysteine-rich [PF08516.14, score=61.3]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=33.1]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=237, Expect=1e-64]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [Score=233, Expect=2e-63]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=230, Expect=2e-62]; ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=228, Expect=4e-61]; ENSG00000069206, ADAM7, ADAM metallopeptidase domain 7, [Score=226, Expect=4e-61]; ENSG00000042980, ADAM28, ADAM metallopeptidase domain 28, [Score=226, Expect=4e-61]} {Mouse: ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [RH, Score=248, Expect=4e-69]; ENSMUSG00000050190, Gm5346, predicted gene 5346, [RH, Score=239, Expect=3e-66]} {Dmel: FBgn0265140, Meltrin, [RH, Score=288, Expect=1e-79]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=246, Expect=3e-67]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=225, Expect=3e-60]} {RNA1509_7654} {RNA1310_9319.1} {RNA815_4173.1}
99. MligTC455_28590 8 0.17 Mlig455_036217

Neo: -

Age: -

 0.973 - - - - 0.973 - Mlig455_036217 {REF} {Length: 55} {NoTransDecoderORF} {RNA1509_51858}
100. MligTC455_29095 291 6.07 Mlig455_008520, Mlig455_062905, Mlig455_064803

Neo: -

Age: -

 0.973 0.973 - - - - -

Mlig455_008520 {REF} {Length: 5586} {RNA1509_55508} {RNA1310_19597} {RNA815_1327.1}

Mlig455_062905 {REF} {Length: 2632} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=121.7]; Endonuclease-reverse transcriptase [PF14529.8, score=48.8]} {Smed: dd_Smed_v6_16441_0_5, dd_Smed_v6_16441_0_5, [Score=105, Expect=8e-24]} {RNA1509_13072, RNA1509_29940} {RNA1310_4523, RNA1509_29940} {RNA1509_29940, RNA815_17419}

Mlig455_064803 {REF} {Length: 1273} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=121.7]; Endonuclease-reverse transcriptase [PF14529.8, score=48.8]} {Smed: dd_Smed_v6_16441_0_5, dd_Smed_v6_16441_0_5, [Score=105, Expect=8e-24]} {RNA1509_13072} {RNA1310_989.1} {RNA815_1327.1}

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