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Results for MligTC455_47666

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_47666 1731 36.07 Mlig455_010849, Mlig455_010878

Neo: -

Age: Down-Up-Up

COQ7

Mlig455_010849 {REF} {Length: 1310} {TRANSSPLICED} {Pfam: Ubiquinone biosynthesis protein COQ7 [PF03232.15, score=227.9]} {Human: ENSG00000167186, COQ7, coenzyme Q7, hydroxylase, [RH, Score=242, Expect=4e-81]} {Mouse: ENSMUSG00000030652, Coq7, demethyl-Q 7, [RH, Score=237, Expect=6e-79]} {Dmel: FBgn0029502, COQ7, [RH, Score=213, Expect=2e-69]} {Celegans: WBGene00000536, clk-1, 5-demethoxyubiquinone hydroxylase, mitochondrial, [RH, Score=197, Expect=8e-64]} {Smed: dd_Smed_v6_5987_0_1, dd_Smed_v6_5987_0_1, [RH, Score=252, Expect=2e-85]} {RNA1509_14595} {RNA1310_11915.1} {RNA815_18967}

Mlig455_010878 {REF} {Length: 1391} {TRANSSPLICED} {Pfam: Ubiquinone biosynthesis protein COQ7 [PF03232.15, score=227.9]} {Human: ENSG00000167186, COQ7, coenzyme Q7, hydroxylase, [RH, Score=242, Expect=4e-81]} {Mouse: ENSMUSG00000030652, Coq7, demethyl-Q 7, [RH, Score=237, Expect=6e-79]} {Dmel: FBgn0029502, COQ7, [RH, Score=213, Expect=2e-69]} {Celegans: WBGene00000536, clk-1, 5-demethoxyubiquinone hydroxylase, mitochondrial, [RH, Score=197, Expect=8e-64]} {Smed: dd_Smed_v6_5987_0_1, dd_Smed_v6_5987_0_1, [RH, Score=252, Expect=2e-85]} {RNA1509_14595, RNA1509_21284} {RNA1310_11915.1, RNA1509_14595, RNA1509_21284} {RNA1509_14595, RNA1509_21284, RNA815_18967}

Cumulative graph for MligTC455_47666

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.166 5.272 0.82941 1.00000
RegionR2 0.626 5.272 0.15539 0.49341
RegionR3 0.203 5.272 0.54604 1.00000
RegionR4 -0.451 5.272 0.28971 0.60015
RegionR5 0.077 5.272 0.80468 1.00000
RegionR6 -0.254 5.272 0.47192 1.00000
RegionR7 -0.414 5.272 0.30311 0.93805
RegionR8 0.379 5.272 0.39578 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 3.068 5.272 0.00102 0.17473
RegenerationR2 -0.403 5.272 0.35791 0.78770
RegenerationR3 0.369 5.272 0.41207 0.81027
RegenerationR4 -0.151 5.272 0.74672 0.96971
RegenerationR5 0.062 5.272 0.87461 1.00000
RegenerationR6 0.137 5.272 0.76246 0.95757
RegenerationBL -0.046 5.272 0.93577 1.00000
RegenerationTP -1.274 5.272 0.03745 0.32218


Genes with expression patterns similar to MligTC455_47666

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_47666 1731 36.07 Mlig455_010849, Mlig455_010878

Neo: -

Age: Down-Up-Up

COQ7 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_010849 {REF} {Length: 1310} {TRANSSPLICED} {Pfam: Ubiquinone biosynthesis protein COQ7 [PF03232.15, score=227.9]} {Human: ENSG00000167186, COQ7, coenzyme Q7, hydroxylase, [RH, Score=242, Expect=4e-81]} {Mouse: ENSMUSG00000030652, Coq7, demethyl-Q 7, [RH, Score=237, Expect=6e-79]} {Dmel: FBgn0029502, COQ7, [RH, Score=213, Expect=2e-69]} {Celegans: WBGene00000536, clk-1, 5-demethoxyubiquinone hydroxylase, mitochondrial, [RH, Score=197, Expect=8e-64]} {Smed: dd_Smed_v6_5987_0_1, dd_Smed_v6_5987_0_1, [RH, Score=252, Expect=2e-85]} {RNA1509_14595} {RNA1310_11915.1} {RNA815_18967}

Mlig455_010878 {REF} {Length: 1391} {TRANSSPLICED} {Pfam: Ubiquinone biosynthesis protein COQ7 [PF03232.15, score=227.9]} {Human: ENSG00000167186, COQ7, coenzyme Q7, hydroxylase, [RH, Score=242, Expect=4e-81]} {Mouse: ENSMUSG00000030652, Coq7, demethyl-Q 7, [RH, Score=237, Expect=6e-79]} {Dmel: FBgn0029502, COQ7, [RH, Score=213, Expect=2e-69]} {Celegans: WBGene00000536, clk-1, 5-demethoxyubiquinone hydroxylase, mitochondrial, [RH, Score=197, Expect=8e-64]} {Smed: dd_Smed_v6_5987_0_1, dd_Smed_v6_5987_0_1, [RH, Score=252, Expect=2e-85]} {RNA1509_14595, RNA1509_21284} {RNA1310_11915.1, RNA1509_14595, RNA1509_21284} {RNA1509_14595, RNA1509_21284, RNA815_18967}
2. MligTC455_30784 405 8.43 Mlig455_004151, Mlig455_017665, Mlig455_066961

Neo: Irradiation

Age: -

Region-enriched R5: 1.460/0.02276

NEK2, PRR9 3.387 - 0.743 0.959 0.722 0.963 -

Mlig455_004151 {REF} {Length: 4735} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=153.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=80.1]; tRNA synthetases class I (R) [PF00750.21, score=63.6]; DALR anticodon binding domain [PF05746.17, score=41.9]; Kinase-like [PF14531.8, score=23.1]} {Human: ENSG00000117650, NEK2, NIMA related kinase 2, [Score=248, Expect=3e-74]} {Mouse: ENSMUSG00000110797, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=239, Expect=2e-70]; ENSMUSG00000026622, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=239, Expect=2e-70]} {Dmel: FBgn0029970, Nek2, [Score=194, Expect=8e-52]} {Celegans: WBGene00021461, nekl-1, NEK (NEver in mitosis Kinase) Like, [Score=143, Expect=7e-35]} {Smed: dd_Smed_v6_5334_0_1, dd_Smed_v6_5334_0_1, [Score=152, Expect=5e-39]} {RNA1509_41013} {RNA1310_16846} {RNA815_14651}

Mlig455_017665 {REF} {Length: 528} {Human: ENSG00000203783, PRR9, proline rich 9, [Score=44.3, Expect=1e-05]}

Mlig455_066961 {REF} {Length: 4870} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=197.5]; tRNA synthetases class I (R) [PF00750.21, score=167.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=123.5]; DALR anticodon binding domain [PF05746.17, score=52.3]; Kinase-like [PF14531.8, score=22.5]} {Human: ENSG00000117650, NEK2, NIMA related kinase 2, [Score=300, Expect=3e-92]} {Mouse: ENSMUSG00000110797, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=291, Expect=2e-88]; ENSMUSG00000026622, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=291, Expect=2e-88]} {Dmel: FBgn0029970, Nek2, [RH, Score=246, Expect=5e-69]} {Celegans: WBGene00008956, nekl-3, Serine/threonine-protein kinase nekl-3, [Score=163, Expect=2e-44]} {Smed: dd_Smed_v6_5334_0_1, dd_Smed_v6_5334_0_1, [RH, Score=254, Expect=1e-74]} {RNA1509_45663} {RNA1310_16846} {RNA815_14651}
3. MligTC455_51134 2716 56.59 Mlig455_005098, Mlig455_005212

Neo: Int S/G2/M

Age: -

3.332 0.724 - 0.793 0.860 0.955 -

Mlig455_005098 {REF} {Length: 1934} {TRANSSPLICED} {Pfam: NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit [PF09782.11, score=59.0]} {Smed: dd_Smed_v6_1994_0_1, dd_Smed_v6_1994_0_1, [RH, Score=103, Expect=3e-27]} {RNA1509_5129} {RNA1310_21673} {RNA815_18893}

Mlig455_005212 {REF} {Length: 3289} {TRANSSPLICED} {Pfam: NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit [PF09782.11, score=59.0]} {Smed: dd_Smed_v6_1994_0_1, dd_Smed_v6_1994_0_1, [RH, Score=103, Expect=2e-27]} {RNA1509_19456, RNA1509_5129, RNA1509_57249} {RNA1310_21673, RNA1509_19456, RNA1509_5129, RNA1509_57249} {RNA1509_19456, RNA1509_5129, RNA1509_57249, RNA815_18893}
4. MligTC455_29541 402 8.37 Mlig455_063794

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.426

2.702 - - 0.850 0.962 - 0.890 Mlig455_063794 {REF} {Length: 3462} {TRANSSPLICED} {RNA1310_21809} {RNA815_37693}
5. MligTC455_53543 1053 21.94 Mlig455_015866, Mlig455_015877, Mlig455_016087

Neo: Irradiation

Age: -

SCAF8 2.668 - - - 0.760 0.978 0.930

Mlig455_015866 {REF} {Length: 4099} {Pfam: CID domain [PF04818.15, score=73.9]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=45.8]; Occluded RNA-recognition motif [PF16842.7, score=29.4]} {Human: ENSG00000213079, SCAF8, SR-related CTD associated factor 8, [RH, Score=199, Expect=5e-52]} {Mouse: ENSMUSG00000046201, Scaf8, SR-related CTD-associated factor 8, [RH, Score=199, Expect=5e-52]; ENSMUSG00000022983, Scaf4, SR-related CTD-associated factor 4, [RH, Score=190, Expect=3e-49]} {Dmel: FBgn0034598, CG4266, [RH, Score=195, Expect=4e-51]} {Celegans: WBGene00017004, nrd-1, NRD (Yeast Nuclear pre-mRNA Down-regulation) homolog, [RH, Score=120, Expect=1e-27]} {Smed: dd_Smed_v6_6238_0_1, dd_Smed_v6_6238_0_1, [RH, Score=391, Expect=2e-123]} {RNA1509_50318, RNA1509_7266} {RNA1310_4601, RNA1509_50318} {RNA1509_50318, RNA815_5349}

Mlig455_015877 {REF} {Length: 4094} {Pfam: CID domain [PF04818.15, score=73.5]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=45.8]; Occluded RNA-recognition motif [PF16842.7, score=29.4]} {Human: ENSG00000213079, SCAF8, SR-related CTD associated factor 8, [RH, Score=199, Expect=6e-52]} {Mouse: ENSMUSG00000046201, Scaf8, SR-related CTD-associated factor 8, [RH, Score=199, Expect=5e-52]; ENSMUSG00000022983, Scaf4, SR-related CTD-associated factor 4, [RH, Score=190, Expect=3e-49]} {Dmel: FBgn0034598, CG4266, [RH, Score=195, Expect=5e-51]} {Celegans: WBGene00017004, nrd-1, NRD (Yeast Nuclear pre-mRNA Down-regulation) homolog, [RH, Score=120, Expect=1e-27]} {Smed: dd_Smed_v6_6238_0_1, dd_Smed_v6_6238_0_1, [RH, Score=389, Expect=1e-122]} {RNA1509_28874, RNA1509_7266} {RNA1310_4601, RNA1509_28874, RNA1509_7266} {RNA1509_28874, RNA1509_7266, RNA815_5349}

Mlig455_016087 {REF} {Length: 4091} {Pfam: CID domain [PF04818.15, score=74.1]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=46.0]; Occluded RNA-recognition motif [PF16842.7, score=29.6]} {Human: ENSG00000213079, SCAF8, SR-related CTD associated factor 8, [RH, Score=200, Expect=2e-52]} {Mouse: ENSMUSG00000046201, Scaf8, SR-related CTD-associated factor 8, [RH, Score=199, Expect=2e-52]; ENSMUSG00000022983, Scaf4, SR-related CTD-associated factor 4, [RH, Score=191, Expect=1e-49]} {Dmel: FBgn0034598, CG4266, [RH, Score=196, Expect=2e-51]} {Celegans: WBGene00017004, nrd-1, NRD (Yeast Nuclear pre-mRNA Down-regulation) homolog, [RH, Score=119, Expect=2e-27]} {Smed: dd_Smed_v6_6238_0_1, dd_Smed_v6_6238_0_1, [RH, Score=391, Expect=4e-124]} {RNA1509_7266} {RNA1310_4601} {RNA815_5349}
6. MligTC455_40942 753 15.68 Mlig455_064008, Mlig455_064049

Neo: -

Age: -

2.666 - - 0.967 - 0.787 0.912

Mlig455_064008 {REF} {Length: 1903} {TRANSSPLICED} {Pfam: NHL repeat [PF01436.23, score=32.9]} {RNA1509_47309} {RNA1310_11375.1} {RNA815_12754}

Mlig455_064049 {REF} {Length: 1939} {TRANSSPLICED} {Pfam: NHL repeat [PF01436.23, score=33.6]} {RNA1509_41158, RNA1509_47309, RNA1509_53907} {RNA1310_11375.1, RNA1509_41158, RNA1509_47309, RNA1509_53907} {RNA1509_41158, RNA1509_47309, RNA1509_53907, RNA815_12754}
7. MligTC455_34785 573 11.94 Mlig455_041077, Mlig455_064718

Neo: Int S/G2/M

Age: Down-Up-Down

SMAD2, SMAD3 2.644 - - - 0.765 0.962 0.917

Mlig455_041077 {REF} {Length: 1953} {Pfam: MH2 domain [PF03166.16, score=164.9]; MH1 domain [PF03165.18, score=24.9]} {Human: ENSG00000175387, SMAD2, SMAD family member 2, [Score=192, Expect=7e-57]; ENSG00000166949, SMAD3, SMAD family member 3, [Score=192, Expect=3e-59]; ENSG00000120693, SMAD9, SMAD family member 9, [Score=191, Expect=2e-56]} {Mouse: ENSMUSG00000024563, Smad2, SMAD family member 2, [Score=192, Expect=5e-57]; ENSMUSG00000032402, Smad3, SMAD family member 3, [Score=192, Expect=4e-57]; ENSMUSG00000027796, Smad9, SMAD family member 9, [Score=188, Expect=2e-55]} {Dmel: FBgn0025800, Smox, Smad on X, [Score=195, Expect=8e-58]} {Celegans: WBGene00004856, sma-2, Dwarfin sma-2, [Score=152, Expect=2e-42]} {Smed: dd_Smed_v6_6079_0_1, dd_Smed_v6_6079_0_1, [Score=186, Expect=3e-54]} {RNA1509_40167} {RNA1310_30032} {RNA815_23614}

Mlig455_064718 {REF} {Length: 1766} {Pfam: MH2 domain [PF03166.16, score=166.1]; MH1 domain [PF03165.18, score=25.0]} {Human: ENSG00000166949, SMAD3, SMAD family member 3, [Score=195, Expect=1e-60]; ENSG00000175387, SMAD2, SMAD family member 2, [Score=195, Expect=4e-58]; ENSG00000120693, SMAD9, SMAD family member 9, [Score=193, Expect=2e-57]} {Mouse: ENSMUSG00000024563, Smad2, SMAD family member 2, [Score=195, Expect=3e-58]; ENSMUSG00000032402, Smad3, SMAD family member 3, [Score=194, Expect=3e-58]; ENSMUSG00000027796, Smad9, SMAD family member 9, [Score=193, Expect=1e-57]} {Dmel: FBgn0025800, Smox, Smad on X, [Score=196, Expect=2e-58]} {Celegans: WBGene00004856, sma-2, Dwarfin sma-2, [Score=153, Expect=6e-43]} {Smed: dd_Smed_v6_6877_0_1, dd_Smed_v6_6877_0_1, [Score=187, Expect=9e-56]} {RNA1509_40167} {RNA1310_30032} {RNA815_23614}
8. MligTC455_13179 625 13.03 Mlig455_006126

Neo: -

Age: logFC(26M/2M)=0.580

RERE 2.642 - - 0.972 0.789 0.881 - Mlig455_006126 {REF} {Length: 3482} {TRANSSPLICED} {Pfam: BAH domain [PF01426.20, score=49.2]; ELM2 domain [PF01448.26, score=36.4]; BUD22 [PF09073.12, score=18.7]; Atrophin-1 family [PF03154.17, score=17.0]} {Human: ENSG00000142599, RERE, arginine-glutamic acid dipeptide repeats, [RH, Score=255, Expect=8e-70]} {Mouse: ENSMUSG00000039852, Rere, arginine glutamic acid dipeptide (RE) repeats, [RH, Score=254, Expect=2e-69]} {Dmel: FBgn0010825, Gug, Grunge, [RH, Score=157, Expect=8e-39]} {Celegans: WBGene00001194, egl-27, Egg-laying defective protein 27, [RH, Score=154, Expect=4e-38]} {Smed: dd_Smed_v6_6341_0_1, dd_Smed_v6_6341_0_1, [RH, Score=191, Expect=1e-49]} {RNA1509_37003, RNA1509_56991} {RNA1310_3861, RNA1509_56991} {RNA1509_56991, RNA815_1114.1}
9. MligTC455_18643 397 8.28 Mlig455_002712

Neo: -

Age: Down-Up-Down

Region-enriched R4: 2.396/0.03057

MFSD13A 2.641 - 0.731 - - 0.965 0.945 Mlig455_002712 {REF} {Length: 2631} {Pfam: MFS/sugar transport protein [PF13347.8, score=59.8]} {Human: ENSG00000138111, MFSD13A, major facilitator superfamily domain containing 13A, [RH, Score=325, Expect=2e-104]} {Mouse: ENSMUSG00000025227, Mfsd13a, major facilitator superfamily domain containing 13a, [RH, Score=343, Expect=8e-112]} {Celegans: WBGene00016174, C27H5.4, [Score=100, Expect=2e-22]} {RNA1509_42736, RNA1509_51069} {RNA1310_16644.1, RNA1509_51069} {RNA1509_51069, RNA815_6472.1}
10. MligTC455_17143 949 19.78 Mlig455_015840, Mlig455_016056

Neo: -

Age: -

Region-enriched R4: 1.171/0.02022

PAN3 2.618 - - - 0.845 0.962 0.811

Mlig455_015840 {REF} {Length: 3953} {TRANSSPLICED} {Pfam: Pan3 Pseudokinase domain [PF18101.3, score=159.3]} {Human: ENSG00000152520, PAN3, poly(A) specific ribonuclease subunit PAN3, [RH, Score=292, Expect=6e-89]} {Mouse: ENSMUSG00000029647, Pan3, PAN3 poly(A) specific ribonuclease subunit, [RH, Score=290, Expect=8e-87]} {Dmel: FBgn0035397, CG11486, [RH, Score=287, Expect=2e-86]} {Celegans: WBGene00014015, panl-3, PAB-dependent poly(A)-specific ribonuclease subunit PAN3, [RH, Score=239, Expect=3e-70]} {Smed: dd_Smed_v6_4588_0_4, dd_Smed_v6_4588_0_4, [RH, Score=353, Expect=1e-112]} {RNA1509_13063} {RNA1310_6283} {RNA815_4137.1}

Mlig455_016056 {REF} {Length: 6356} {TRANSSPLICED} {Pfam: Pan3 Pseudokinase domain [PF18101.3, score=159.2]} {Human: ENSG00000152520, PAN3, poly(A) specific ribonuclease subunit PAN3, [RH, Score=291, Expect=9e-89]} {Mouse: ENSMUSG00000029647, Pan3, PAN3 poly(A) specific ribonuclease subunit, [RH, Score=291, Expect=1e-88]} {Dmel: FBgn0035397, CG11486, [RH, Score=286, Expect=5e-86]} {Celegans: WBGene00014015, panl-3, PAB-dependent poly(A)-specific ribonuclease subunit PAN3, [RH, Score=240, Expect=2e-70]} {Smed: dd_Smed_v6_4588_0_4, dd_Smed_v6_4588_0_4, [RH, Score=354, Expect=6e-113]} {RNA1509_13063} {RNA1310_6283, RNA1509_13063} {RNA1509_13063, RNA815_4137.1}
11. MligTC455_21676 842 17.54 Mlig455_054899

Neo: -

Age: -

USP8 2.567 - - 0.967 0.774 0.826 - Mlig455_054899 {REF} {Length: 4637} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=271.7]; USP8 dimerisation domain [PF08969.13, score=62.1]; Ubiquitin carboxyl-terminal hydrolase [PF13423.8, score=51.3]; WW domain [PF00397.28, score=20.0]} {Human: ENSG00000138592, USP8, ubiquitin specific peptidase 8, [RH, Score=397, Expect=4e-121]} {Mouse: ENSMUSG00000027363, Usp8, ubiquitin specific peptidase 8, [RH, Score=397, Expect=9e-121]} {Dmel: FBgn0038862, Usp8, Ubiquitin specific protease 8, [RH, Score=291, Expect=8e-84]} {Celegans: WBGene00008441, usp-50, Ubiquitin Specific Protease, [RH, Score=189, Expect=2e-49]} {Smed: dd_Smed_v6_6489_0_1, dd_Smed_v6_6489_0_1, [RH, Score=413, Expect=5e-128]} {RNA1509_53998, RNA1509_58936, RNA1509_6279} {RNA1310_6785.1, RNA1509_53998, RNA1509_58936, RNA1509_6279} {RNA1509_53998, RNA1509_58936, RNA1509_6279, RNA815_11966}
12. MligTC455_46213 262 5.46 Mlig455_028789

Neo: -

Age: -

2.559 - - - 0.718 0.953 0.888 Mlig455_028789 {REF} {Length: 1745} {TRANSSPLICED} {RNA1509_57405} {RNA1310_35325} {RNA815_25882}
13. MligTC455_21221 389 8.1 Mlig455_050465

Neo: -

Age: -

CLNS1A 2.546 0.701 - 0.961 - 0.884 - Mlig455_050465 {REF} {Length: 3185} {Pfam: Regulator of volume decrease after cellular swelling [PF03517.15, score=77.4]} {Human: ENSG00000074201, CLNS1A, chloride nucleotide-sensitive channel 1A, [RH, Score=82.0, Expect=2e-17]} {Mouse: ENSMUSG00000025439, Clns1a, chloride channel, nucleotide-sensitive, 1A, [RH, Score=85.1, Expect=3e-18]} {Dmel: FBgn0029079, icln, [Score=58.2, Expect=3e-09]} {Celegans: WBGene00002046, icln-1, ICLN (ICLn) ion channel homolog; ICln1, [RH, Score=57.0, Expect=5e-09]} {RNA1509_15891} {RNA1310_42426, RNA1509_15891} {RNA1509_15891, RNA815_3258.1}
14. MligTC455_49438 801 16.68 Mlig455_012610

Neo: Int S/G2/M

Age: Down-Up-Up

Region-enriched R4: 1.791/0.00443
Region-enriched R5: 1.586/0.00013

C9orf85 2.51 0.719 - 0.831 - 0.960 - Mlig455_012610 {REF} {Length: 675} {TRANSSPLICED} {Pfam: Uncharacterized conserved protein (DUF2039) [PF10217.11, score=86.8]} {Human: ENSG00000155621, C9orf85, chromosome 9 open reading frame 85, [RH, Score=112, Expect=8e-31]} {Mouse: ENSMUSG00000035171, 1110059E24Rik, RIKEN cDNA 1110059E24 gene, [RH, Score=112, Expect=2e-31]} {Dmel: FBgn0030834, CG8675, [RH, Score=112, Expect=1e-30]} {Smed: dd_Smed_v6_8807_0_1, dd_Smed_v6_8807_0_1, [RH, Score=104, Expect=3e-28]} {RNA1509_23122, RNA1509_57242} {RNA1310_54864.2, RNA1509_23122, RNA1509_57242} {RNA1509_23122, RNA1509_57242, RNA815_26692}
15. MligTC455_45235 418 8.71 Mlig455_044515

Neo: Int S/G2/M

Age: -

GSTT1 2.476 - - - 0.755 0.765 0.956 Mlig455_044515 {REF} {Length: 1303} {Pfam: Glutathione S-transferase, N-terminal domain [PF02798.22, score=42.4]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=32.2]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=30.2]} {Human: ENSG00000277656, GSTT1, glutathione S-transferase theta 1, [Score=115, Expect=3e-31]} {Mouse: ENSMUSG00000001663, Gstt1, glutathione S-transferase, theta 1, [Score=114, Expect=7e-31]; ENSMUSG00000001665, Gstt3, glutathione S-transferase, theta 3, [Score=111, Expect=3e-30]; ENSMUSG00000092360, Gm20441, predicted gene 20441, [Score=110, Expect=4e-29]} {Dmel: FBgn0050000, GstT1, Glutathione S transferase T1, [Score=95.5, Expect=6e-24]} {Smed: dd_Smed_v6_5451_0_1, dd_Smed_v6_5451_0_1, [Score=94.4, Expect=1e-23]} {RNA1509_7848} {RNA1310_26118} {RNA815_12339}
16. MligTC455_49309 585 12.19 Mlig455_023541

Neo: -

Age: -

2.472 - - 0.951 0.812 0.709 - Mlig455_023541 {REF} {Length: 5523} {Celegans: WBGene00022664, ZK121.2, [Score=49.7, Expect=6e-06]} {Smed: dd_Smed_v6_9972_0_1, dd_Smed_v6_9972_0_1, [Score=50.1, Expect=1e-06]} {RNA1509_4676} {RNA1310_6238, RNA1509_4676} {RNA1509_4676, RNA815_12656}
17. MligTC455_51957 427 8.9 Mlig455_001616

Neo: -

Age: logFC(26M/2M)=0.792

LCK 2.458 - - 0.952 0.764 0.742 - Mlig455_001616 {REF} {Length: 2834} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=195.1]; Protein kinase domain [PF00069.27, score=130.1]; Variant SH3 domain [PF14604.8, score=43.0]; SH2 domain [PF00017.26, score=42.8]; Variant SH3 domain [PF07653.19, score=36.6]; SH3 domain [PF00018.30, score=35.8]; ABC1 atypical kinase-like domain [PF03109.18, score=28.0]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=251, Expect=7e-78]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=250, Expect=5e-77]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=241, Expect=1e-73]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=255, Expect=4e-79]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=243, Expect=7e-75]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=239, Expect=4e-73]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=213, Expect=5e-64]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=304, Expect=6e-99]} {RNA1509_10615, RNA1509_47356} {RNA1310_9006.1, RNA1509_47356} {RNA1509_47356, RNA815_3005.1}
18. MligTC455_19945 635 13.23 Mlig455_004844

Neo: Int S/G2/M

Age: Down-Up-Up

Region-enriched R5: 1.886/0.00002
Region-enriched R4: 1.500/0.02485

SLC30A7 2.453 0.738 - - 0.736 0.979 - Mlig455_004844 {REF} {Length: 543} {TRANSSPLICED} {Pfam: Cation efflux family [PF01545.23, score=168.4]; Rpp14/Pop5 family [PF01900.21, score=71.5]} {Human: ENSG00000162695, SLC30A7, solute carrier family 30 member 7, [Score=431, Expect=1e-148]} {Mouse: ENSMUSG00000054414, Slc30a7, solute carrier family 30 (zinc transporter), member 7, [Score=416, Expect=8e-143]} {Dmel: FBgn0037875, ZnT86D, Zinc transporter 86D, [RH, Score=384, Expect=2e-130]} {Celegans: WBGene00000393, cdf-1, Cation diffusion facilitator family protein 1, [Score=102, Expect=6e-23]} {Smed: dd_Smed_v6_4378_0_1, dd_Smed_v6_4378_0_1, [Score=243, Expect=7e-72]} {RNA1509_34159, RNA1509_39378} {RNA1310_60743, RNA1509_34159, RNA1509_39378} {RNA1509_34159, RNA1509_39378, RNA815_30594}
19. MligTC455_52338 341 7.1 Mlig455_008924

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.465

C2orf76 2.441 - 0.741 - 0.738 0.962 - Mlig455_008924 {REF} {Length: 2124} {TRANSSPLICED} {Pfam: Uncharacterized conserved protein (DUF2340) [PF10209.11, score=127.4]} {Human: ENSG00000186132, C2orf76, chromosome 2 open reading frame 76, [RH, Score=97.1, Expect=2e-26]} {Mouse: ENSMUSG00000026388, 3110009E18Rik, RIKEN cDNA 3110009E18 gene, [RH, Score=92.0, Expect=1e-24]} {RNA1509_25259, RNA1509_33285} {RNA1310_9901.1, RNA1509_25259, RNA1509_33285} {RNA1509_25259, RNA1509_33285, RNA815_28452}
20. MligTC455_50130 149 3.11 Mlig455_000637

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.523

1.942 - - 0.971 - 0.971 - Mlig455_000637 {REF} {Length: 3012} {RNA1509_32590} {RNA1310_8641.2, RNA1509_32590} {RNA1509_32590, RNA815_3178.1}
21. MligTC455_47639 256 5.34 Mlig455_046133

Neo: -

Age: -

USF2 1.914 - - 0.962 - - 0.952 Mlig455_046133 {REF} {Length: 1681} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=50.4]} {Human: ENSG00000105698, USF2, upstream transcription factor 2, c-fos interacting, [Score=59.3, Expect=1e-09]} {Mouse: ENSMUSG00000058239, Usf2, upstream transcription factor 2, [Score=57.8, Expect=6e-09]} {Dmel: FBgn0029711, Usf, [Score=54.7, Expect=5e-08]} {Smed: dd_Smed_v6_4871_0_1, dd_Smed_v6_4871_0_1, [RH, Score=55.5, Expect=2e-08]} {RNA1509_24437} {RNA1310_26406} {RNA815_7684}
22. MligTC455_22826 607 12.65 Mlig455_006871

Neo: -

Age: -

ATG4C 1.913 - - 0.949 - - 0.964 Mlig455_006871 {REF} {Length: 5184} {TRANSSPLICED} {Pfam: Peptidase family C54 [PF03416.21, score=188.3]; Ribosomal protein L6 [PF00347.25, score=41.0]} {Human: ENSG00000125703, ATG4C, autophagy related 4C cysteine peptidase, [Score=142, Expect=2e-36]} {Mouse: ENSMUSG00000028550, Atg4c, autophagy related 4C, cysteine peptidase, [Score=137, Expect=1e-34]; ENSMUSG00000002820, Atg4d, autophagy related 4D, cysteine peptidase, [Score=137, Expect=1e-34]} {Dmel: FBgn0038325, Atg4b, Autophagy-related 4b, [Score=134, Expect=9e-33]} {Celegans: WBGene00013595, atg-4.1, Cysteine protease, [Score=127, Expect=1e-31]} {Smed: dd_Smed_v6_10824_0_1, dd_Smed_v6_10824_0_1, [RH, Score=162, Expect=1e-43]} {RNA1509_29780} {RNA1310_15687.1} {RNA815_37674}
23. MligTC455_29718 108 2.25 Mlig455_021509

Neo: -

Age: -

HELZ2 1.913 - - - - 0.957 0.956 Mlig455_021509 {REF} {Length: 8247} {Pfam: RNB domain [PF00773.21, score=194.3]; AAA domain [PF13086.8, score=135.4]; AAA domain [PF13087.8, score=127.8]; AAA domain [PF13604.8, score=32.3]; AAA domain [PF13245.8, score=23.3]; Dis3-like cold-shock domain 2 (CSD2) [PF17849.3, score=21.1]; Type II/IV secretion system protein [PF00437.22, score=18.1]} {Human: ENSG00000130589, HELZ2, helicase with zinc finger 2, [Score=211, Expect=4e-54]} {Mouse: ENSMUSG00000027580, Helz2, helicase with zinc finger 2, transcriptional coactivator, [Score=281, Expect=1e-75]} {Dmel: FBgn0039183, Dis3, [Score=126, Expect=1e-28]} {Celegans: WBGene00004880, smg-2, Regulator of nonsense transcripts 1, [Score=101, Expect=3e-21]} {Smed: dd_Smed_v6_7048_0_2, dd_Smed_v6_7048_0_2, [Score=284, Expect=5e-77]} {RNA1509_22882, RNA1509_5117, RNA1509_8567} {RNA1310_536, RNA1509_22882, RNA1509_8567} {RNA1509_22882, RNA1509_8567, RNA815_182.1}
24. MligTC455_23237 505 10.52 Mlig455_007444

Neo: -

Age: -

TMEM258 1.906 - - - - 0.954 0.952 Mlig455_007444 {REF} {Length: 4417} {Pfam: Oligosaccharyltransferase subunit 5 [PF05251.14, score=81.6]} {Human: ENSG00000134825, TMEM258, transmembrane protein 258, [RH, Score=131, Expect=8e-36]} {Mouse: ENSMUSG00000036372, Tmem258, transmembrane protein 258, [RH, Score=131, Expect=6e-36]} {Dmel: FBgn0036667, CG9669, [RH, Score=97.1, Expect=4e-24]} {Celegans: WBGene00021960, Y57E12AM.1, Transmembrane protein 258 homolog, [Score=72.8, Expect=9e-16]} {Smed: dd_Smed_v6_1016_0_1, dd_Smed_v6_1016_0_1, [RH, Score=134, Expect=2e-37]} {RNA1509_16085, RNA1509_43363} {RNA1310_12186, RNA1509_16085, RNA1509_43363} {RNA1509_16085, RNA1509_43363, RNA815_10743}
25. MligTC455_09772 568 11.83 Mlig455_007711

Neo: -

Age: -

1.902 - - - - 0.946 0.956 Mlig455_007711 {REF} {Length: 762} {Pfam: RNase H [PF00075.26, score=32.9]; zinc-binding in reverse transcriptase [PF13966.8, score=20.5]} {RNA1509_42121} {RNA1310_28357.1} {RNA815_28691}
26. MligTC455_15964 150 3.13 Mlig455_041648

Neo: -

Age: -

SMAD4 1.9 - - - - 0.957 0.943 Mlig455_041648 {REF} {Length: 2630} {TRANSSPLICED} {Pfam: MH2 domain [PF03166.16, score=213.5]; MH1 domain [PF03165.18, score=129.8]} {Human: ENSG00000141646, SMAD4, SMAD family member 4, [Score=447, Expect=1e-153]} {Mouse: ENSMUSG00000024515, Smad4, SMAD family member 4, [Score=442, Expect=6e-151]} {Dmel: FBgn0011655, Med, Medea, [Score=278, Expect=1e-85]} {Celegans: WBGene00004858, sma-4, Dwarfin sma-4, [Score=288, Expect=5e-91]} {Smed: dd_Smed_v6_1923_0_1, dd_Smed_v6_1923_0_1, [Score=282, Expect=4e-88]} {RNA1509_20434, RNA1509_52834, RNA1509_58190} {RNA1310_15699.1, RNA1509_20434, RNA1509_52834, RNA1509_58190} {RNA1509_20434, RNA1509_52834, RNA1509_58190, RNA815_20871}
27. MligTC455_28780 110 2.3 Mlig455_054223

Neo: -

Age: Up-Down-Up

TANC2 1.9 - - 0.950 - 0.950 - Mlig455_054223 {REF} {Length: 4977} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=48.3]; Mab-21 protein [PF03281.16, score=44.1]; Ankyrin repeats (3 copies) [PF12796.9, score=42.1]; Ankyrin repeats (many copies) [PF13857.8, score=37.1]; Ankyrin repeat [PF13606.8, score=34.3]; Ankyrin repeat [PF00023.32, score=33.2]} {Human: ENSG00000170921, TANC2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=68.6, Expect=6e-11]} {Mouse: ENSMUSG00000053580, Tanc2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=68.6, Expect=4e-11]} {Dmel: FBgn0041096, rols, rolling pebbles, [Score=68.6, Expect=2e-11]} {Celegans: WBGene00011240, R11A8.7, Ankyrin repeat and KH domain-containing protein R11A8.7, [Score=61.6, Expect=3e-09]} {Smed: dd_Smed_v6_6779_0_1, dd_Smed_v6_6779_0_1, [Score=57.8, Expect=3e-08]} {RNA1509_27730} {RNA1310_4721} {RNA815_5358.1}
28. MligTC455_29829 695 14.47 Mlig455_017371

Neo: -

Age: -

RPS6KB1 1.899 - - 0.965 - - 0.934 Mlig455_017371 {REF} {Length: 5768} {Pfam: Protein kinase domain [PF00069.27, score=226.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=112.9]; Protein kinase C terminal domain [PF00433.26, score=32.7]; Kinase-like [PF14531.8, score=21.9]; Kinetochore Sim4 complex subunit FTA2 [PF13095.8, score=19.2]} {Human: ENSG00000108443, RPS6KB1, ribosomal protein S6 kinase B1, [RH, Score=494, Expect=2e-171]; ENSG00000175634, RPS6KB2, ribosomal protein S6 kinase B2, [RH, Score=478, Expect=8e-165]} {Mouse: ENSMUSG00000020516, Rps6kb1, ribosomal protein S6 kinase, polypeptide 1, [RH, Score=494, Expect=9e-171]} {Dmel: FBgn0283472, S6k, Ribosomal protein S6 kinase, [RH, Score=466, Expect=2e-160]} {Celegans: WBGene00012929, rsks-1, Ribosomal protein S6 kinase beta, [RH, Score=469, Expect=1e-160]} {Smed: dd_Smed_v6_5658_0_1, dd_Smed_v6_5658_0_1, [RH, Score=469, Expect=1e-161]} {RNA1509_43095, RNA1509_7605} {RNA1310_19244, RNA1509_43095} {RNA1509_43095, RNA815_2217.1}
29. MligTC455_12877 194 4.05 Mlig455_003083

Neo: -

Age: -

1.898 - - 0.953 - - 0.945 Mlig455_003083 {REF} {Length: 2223} {NoTransDecoderORF} {RNA1310_65454} {RNA815_34920}
30. MligTC455_31499 4185 87.19 Mlig455_007762, Mlig455_056589, Mlig455_056611

Neo: -

Age: -

PSMD4 1.897 - - 0.955 0.942 - -

Mlig455_007762 {REF} {Length: 3355} {TRANSSPLICED} {Pfam: von Willebrand factor type A domain [PF13519.8, score=59.8]; RAP80 N-terminal ubiquitin interaction motif [PF18282.3, score=21.8]; Ubiquitin interaction motif [PF02809.22, score=20.7]} {Human: ENSG00000159352, PSMD4, proteasome 26S subunit, non-ATPase 4, [RH, Score=342, Expect=6e-115]} {Mouse: ENSMUSG00000005625, Psmd4, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4, [RH, Score=341, Expect=1e-114]} {Dmel: FBgn0015283, Rpn10, Regulatory particle non-ATPase 10, [RH, Score=317, Expect=6e-105]} {Celegans: WBGene00004466, rpn-10, 26S proteasome non-ATPase regulatory subunit 4, [RH, Score=214, Expect=9e-66]} {Smed: dd_Smed_v6_1231_0_1, dd_Smed_v6_1231_0_1, [RH, Score=245, Expect=6e-78]} {RNA1509_19280, RNA1509_20122, RNA1509_2886, RNA1509_8983} {RNA1310_11583, RNA1509_19280, RNA1509_20122, RNA1509_8983} {RNA1509_19280, RNA1509_20122, RNA1509_8983, RNA815_4417}

Mlig455_056589 {REF} {Length: 2304} {TRANSSPLICED} {Pfam: von Willebrand factor type A domain [PF13519.8, score=59.8]; RAP80 N-terminal ubiquitin interaction motif [PF18282.3, score=21.8]; Ubiquitin interaction motif [PF02809.22, score=20.7]} {Human: ENSG00000159352, PSMD4, proteasome 26S subunit, non-ATPase 4, [RH, Score=343, Expect=2e-115]} {Mouse: ENSMUSG00000005625, Psmd4, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4, [RH, Score=343, Expect=2e-115]} {Dmel: FBgn0015283, Rpn10, Regulatory particle non-ATPase 10, [RH, Score=318, Expect=2e-105]} {Celegans: WBGene00004466, rpn-10, 26S proteasome non-ATPase regulatory subunit 4, [RH, Score=213, Expect=1e-65]} {Smed: dd_Smed_v6_1231_0_1, dd_Smed_v6_1231_0_1, [RH, Score=246, Expect=6e-78]} {RNA1509_2886} {RNA1310_11583} {RNA815_4417}

Mlig455_056611 {REF} {Length: 2309} {TRANSSPLICED} {Pfam: von Willebrand factor type A domain [PF13519.8, score=59.8]; RAP80 N-terminal ubiquitin interaction motif [PF18282.3, score=21.8]; Ubiquitin interaction motif [PF02809.22, score=20.7]} {Human: ENSG00000159352, PSMD4, proteasome 26S subunit, non-ATPase 4, [RH, Score=343, Expect=2e-115]} {Mouse: ENSMUSG00000005625, Psmd4, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4, [RH, Score=343, Expect=2e-115]} {Dmel: FBgn0015283, Rpn10, Regulatory particle non-ATPase 10, [RH, Score=318, Expect=2e-105]} {Celegans: WBGene00004466, rpn-10, 26S proteasome non-ATPase regulatory subunit 4, [RH, Score=213, Expect=1e-65]} {Smed: dd_Smed_v6_1231_0_1, dd_Smed_v6_1231_0_1, [RH, Score=246, Expect=6e-78]} {RNA1509_14233, RNA1509_2886} {RNA1310_11583, RNA1509_14233, RNA1509_2886} {RNA1509_14233, RNA1509_2886, RNA815_4417}
31. MligTC455_27899 402 8.38 Mlig455_001980, Mlig455_002076, Mlig455_002182

Neo: -

Age: -

PIWIL1 1.896 - - 0.918 - 0.978 -

Mlig455_001980 {REF} {Length: 3123} {TRANSSPLICED} {Pfam: Piwi domain [PF02171.19, score=214.0]} {Human: ENSG00000125207, PIWIL1, piwi like RNA-mediated gene silencing 1, [Score=237, Expect=9e-68]; ENSG00000275051, PIWIL1, piwi like RNA-mediated gene silencing 1, [Score=237, Expect=9e-68]} {Mouse: ENSMUSG00000029423, Piwil1, piwi-like RNA-mediated gene silencing 1, [Score=238, Expect=2e-68]} {Dmel: FBgn0250816, AGO3, Argonaute 3, [Score=215, Expect=4e-60]} {Celegans: WBGene00004178, prg-1, Piwi-like protein, [Score=198, Expect=2e-54]} {Smed: dd_Smed_v6_1258_0_1, dd_Smed_v6_1258_0_1, [Score=216, Expect=2e-60]} {RNA1310_29501} {RNA815_13438}

Mlig455_002076 {REF} {Length: 3896} {Pfam: PAZ domain [PF02170.24, score=66.6]} {Human: ENSG00000125207, PIWIL1, piwi like RNA-mediated gene silencing 1, [Score=148, Expect=2e-38]; ENSG00000275051, PIWIL1, piwi like RNA-mediated gene silencing 1, [Score=148, Expect=2e-38]; ENSG00000134627, PIWIL4, piwi like RNA-mediated gene silencing 4, [Score=142, Expect=4e-37]} {Mouse: ENSMUSG00000029423, Piwil1, piwi-like RNA-mediated gene silencing 1, [Score=152, Expect=3e-41]; ENSMUSG00000036912, Piwil4, piwi-like RNA-mediated gene silencing 4, [Score=145, Expect=2e-37]} {Dmel: FBgn0004872, piwi, P-element induced wimpy testis, [Score=129, Expect=2e-32]} {Celegans: WBGene00004178, prg-1, Piwi-like protein, [Score=103, Expect=1e-23]} {Smed: dd_Smed_v6_1258_0_1, dd_Smed_v6_1258_0_1, [Score=134, Expect=5e-34]} {RNA1310_27950.1} {RNA815_14157}

Mlig455_002182 {REF} {Length: 3834} {Pfam: Piwi domain [PF02171.19, score=205.4]} {Human: ENSG00000125207, PIWIL1, piwi like RNA-mediated gene silencing 1, [Score=223, Expect=1e-66]; ENSG00000275051, PIWIL1, piwi like RNA-mediated gene silencing 1, [Score=223, Expect=1e-66]} {Mouse: ENSMUSG00000029423, Piwil1, piwi-like RNA-mediated gene silencing 1, [Score=227, Expect=4e-68]} {Dmel: FBgn0250816, AGO3, Argonaute 3, [Score=201, Expect=8e-59]} {Celegans: WBGene00004179, prg-2, Piwi-like protein, [Score=184, Expect=2e-53]} {Smed: dd_Smed_v6_1258_0_1, dd_Smed_v6_1258_0_1, [Score=204, Expect=7e-60]} {RNA1509_13122} {RNA1310_29501} {RNA815_13438}
32. MligTC455_20418 213 4.45 Mlig455_003920

Neo: -

Age: -

1.895 - - - - 0.951 0.944 Mlig455_003920 {REF} {Length: 3500} {Pfam: Ring finger domain [PF13639.8, score=19.8]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=18.9]} {RNA1509_20350, RNA1509_23231} {RNA1310_6875, RNA1509_20350, RNA1509_23231} {RNA1509_20350, RNA1509_23231, RNA815_2399.1}
33. MligTC455_19655 475 9.9 Mlig455_064127

Neo: -

Age: -

1.894 - - - - 0.958 0.936 Mlig455_064127 {REF} {Length: 378} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_20237} {RNA1310_90847, RNA1509_20237} {RNA1509_20237, RNA815_48534}
34. MligTC455_23756 324 6.75 Mlig455_015157

Neo: -

Age: -

MOCS3 1.893 - - 0.953 - - 0.940 Mlig455_015157 {REF} {Length: 2497} {TRANSSPLICED} {Pfam: ThiF family [PF00899.23, score=204.2]; Rhodanese-like domain [PF00581.22, score=30.5]} {Human: ENSG00000124217, MOCS3, molybdenum cofactor synthesis 3, [RH, Score=342, Expect=1e-113]} {Mouse: ENSMUSG00000074576, Mocs3, molybdenum cofactor synthesis 3, [RH, Score=349, Expect=2e-116]} {Dmel: FBgn0032054, Uba4, Ubiquitin activating enzyme 4, [RH, Score=365, Expect=5e-123]} {Celegans: WBGene00018357, moc-3, Adenylyltransferase and sulfurtransferase MOCS3 Molybdopterin-synthase adenylyltransferase Molybdopterin-synthase sulfurtransferase, [RH, Score=325, Expect=4e-108]} {Smed: dd_Smed_v6_5985_0_1, dd_Smed_v6_5985_0_1, [RH, Score=345, Expect=2e-115]} {RNA1509_31779, RNA1509_4475} {RNA1310_9289.1, RNA1509_31779} {RNA1509_31779, RNA815_6343.1}
35. MligTC455_21029 256 5.33 Mlig455_040148

Neo: -

Age: -

NOTCH4 1.892 - - 0.953 - 0.939 - Mlig455_040148 {REF} {Length: 3010} {Pfam: Calcium-binding EGF domain [PF07645.17, score=211.2]; EGF-like domain [PF00008.29, score=172.1]; Human growth factor-like EGF [PF12661.9, score=120.3]; EGF domain [PF12947.9, score=105.0]; EGF-like domain [PF07974.15, score=70.4]; Delta serrate ligand [PF01414.21, score=56.9]; Complement Clr-like EGF-like [PF12662.9, score=47.4]; PT repeat [PF04886.14, score=25.6]} {Human: ENSG00000235396, NOTCH4, notch 4, [Score=285, Expect=1e-81]; ENSG00000206312, NOTCH4, notch 4, [Score=283, Expect=8e-81]; ENSG00000232339, NOTCH4, notch 4, [Score=283, Expect=5e-81]; ENSG00000234876, NOTCH4, notch 4, [Score=283, Expect=8e-81]; ENSG00000204301, NOTCH4, notch 4, [Score=283, Expect=8e-81]; ENSG00000223355, NOTCH4, notch 4, [Score=283, Expect=5e-81]; ENSG00000134250, NOTCH2, notch 2, [Score=282, Expect=1e-80]; ENSG00000074181, NOTCH3, notch 3, [Score=275, Expect=2e-78]; ENSG00000148400, NOTCH1, notch 1, [Score=271, Expect=5e-77]} {Mouse: ENSMUSG00000027878, Notch2, notch 2, [Score=279, Expect=1e-79]; ENSMUSG00000038146, Notch3, notch 3, [Score=278, Expect=1e-79]; ENSMUSG00000026923, Notch1, notch 1, [Score=274, Expect=4e-78]} {Dmel: FBgn0004647, N, Notch, [Score=277, Expect=4e-79]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=231, Expect=6e-64]} {Smed: dd_Smed_v6_13823_0_1, dd_Smed_v6_13823_0_1, [Score=221, Expect=3e-61]} {RNA1509_25481} {RNA1310_18275.1, RNA1509_25481} {RNA1509_25481, RNA815_2179.1}
36. MligTC455_51421 384 8 Mlig455_039791

Neo: -

Age: Down-Up-Up

MGLL 1.892 - - - - 0.967 0.925 Mlig455_039791 {REF} {Length: 1425} {Pfam: Serine aminopeptidase, S33 [PF12146.10, score=183.8]; Alpha/beta hydrolase family [PF12697.9, score=50.6]; alpha/beta hydrolase fold [PF00561.22, score=29.1]; Protein of unknown function (DUF2920) [PF11144.10, score=24.7]; Prolyl oligopeptidase family [PF00326.23, score=23.1]; Putative esterase [PF00756.22, score=20.6]} {Human: ENSG00000074416, MGLL, monoglyceride lipase, [RH, Score=141, Expect=2e-39]} {Mouse: ENSMUSG00000033174, Mgll, monoglyceride lipase, [RH, Score=144, Expect=6e-41]} {Smed: dd_Smed_v6_6796_0_1, dd_Smed_v6_6796_0_1, [RH, Score=139, Expect=2e-39]} {RNA1509_12132} {RNA1310_13222} {RNA815_8057}
37. MligTC455_16286 1029 21.44 Mlig455_067405, Mlig455_069542

Neo: -

Age: -

CSRNP2 1.891 - - - - 0.958 0.933

Mlig455_067405 {REF} {Length: 1792} {TRANSSPLICED} {Pfam: Cysteine/serine-rich nuclear protein N-terminus [PF16019.7, score=168.5]} {Human: ENSG00000110925, CSRNP2, cysteine and serine rich nuclear protein 2, [RH, Score=139, Expect=1e-35]} {Mouse: ENSMUSG00000044636, Csrnp2, cysteine-serine-rich nuclear protein 2, [RH, Score=139, Expect=9e-36]} {Dmel: FBgn0261647, Axud1, AXIN1 up-regulated 1, [RH, Score=149, Expect=1e-38]} {Smed: dd_Smed_v6_9797_0_1, dd_Smed_v6_9797_0_1, [RH, Score=149, Expect=6e-39]} {RNA1509_21091} {RNA1310_24252} {RNA815_13620.1}

Mlig455_069542 {REF} {Length: 1793} {TRANSSPLICED} {Pfam: Cysteine/serine-rich nuclear protein N-terminus [PF16019.7, score=168.6]} {Human: ENSG00000110925, CSRNP2, cysteine and serine rich nuclear protein 2, [RH, Score=139, Expect=8e-36]} {Mouse: ENSMUSG00000044636, Csrnp2, cysteine-serine-rich nuclear protein 2, [RH, Score=139, Expect=5e-36]} {Dmel: FBgn0261647, Axud1, AXIN1 up-regulated 1, [RH, Score=149, Expect=6e-39]} {Smed: dd_Smed_v6_9797_0_1, dd_Smed_v6_9797_0_1, [RH, Score=149, Expect=3e-39]} {RNA1509_21091} {RNA1310_24252} {RNA815_13620.1}
38. MligTC455_18642 402 8.37 Mlig455_002696

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.315/0.01369

MFSD13A 1.891 - - - - 0.963 0.928 Mlig455_002696 {REF} {Length: 2673} {Human: ENSG00000138111, MFSD13A, major facilitator superfamily domain containing 13A, [Score=125, Expect=8e-33]} {Mouse: ENSMUSG00000025227, Mfsd13a, major facilitator superfamily domain containing 13a, [Score=124, Expect=2e-32]} {RNA1509_42736} {RNA1310_16644.2} {RNA815_6472.1}
39. MligTC455_10714 75 1.57 Mlig455_014408, Mlig455_070162

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.165

Region-enriched R4: 4.566/0.03282

RSPH9 1.888 - - 0.965 - 0.923 -

Mlig455_014408 {REF} {Length: 742} {TRANSSPLICED} {Pfam: Radial spokehead-like protein [PF04712.14, score=26.0]} {Human: ENSG00000172426, RSPH9, radial spoke head 9 homolog, [Score=122, Expect=6e-33]} {Mouse: ENSMUSG00000023966, Rsph9, radial spoke head 9 homolog (Chlamydomonas), [Score=120, Expect=1e-32]} {Dmel: FBgn0051803, CG31803, [Score=85.1, Expect=2e-19]} {Smed: dd_Smed_v6_4707_0_1, dd_Smed_v6_4707_0_1, [Score=182, Expect=1e-56]} {RNA1509_33851} {RNA1310_6070} {RNA815_13422}

Mlig455_070162 {REF} {Length: 1222} {TRANSSPLICED} {Pfam: Radial spokehead-like protein [PF04712.14, score=45.8]} {Human: ENSG00000172426, RSPH9, radial spoke head 9 homolog, [RH, Score=278, Expect=1e-91]} {Mouse: ENSMUSG00000023966, Rsph9, radial spoke head 9 homolog (Chlamydomonas), [RH, Score=270, Expect=1e-88]} {Dmel: FBgn0051803, CG31803, [RH, Score=178, Expect=6e-53]} {Smed: dd_Smed_v6_4707_0_1, dd_Smed_v6_4707_0_1, [RH, Score=364, Expect=6e-126]} {RNA1509_33851} {RNA1310_6070} {RNA815_13422}
40. MligTC455_26752 385 8.01 Mlig455_008992

Neo: -

Age: -

TCF7L1 1.888 - - 0.958 - - 0.930 Mlig455_008992 {REF} {Length: 5247} {TRANSSPLICED} {Pfam: HMG (high mobility group) box [PF00505.21, score=76.2]; HMG-box domain [PF09011.12, score=32.7]} {Human: ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=148, Expect=1e-37]; ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=145, Expect=6e-38]} {Mouse: ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=149, Expect=3e-38]; ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=145, Expect=3e-38]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=150, Expect=5e-38]} {Celegans: WBGene00004077, pop-1, [RH, Score=108, Expect=4e-25]} {Smed: dd_Smed_v6_9140_0_1, dd_Smed_v6_9140_0_1, [RH, Score=157, Expect=1e-40]} {RNA1509_11661} {RNA1310_5451.3, RNA1509_11661} {RNA1509_11661, RNA815_18426}
41. MligTC455_43768 354 7.38 Mlig455_027547

Neo: -

Age: -

STK11 1.885 - - 0.916 - - 0.969 Mlig455_027547 {REF} {Length: 2652} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=156.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=91.1]; Kinase-like [PF14531.8, score=26.1]; ABC1 atypical kinase-like domain [PF03109.18, score=19.0]} {Human: ENSG00000118046, STK11, serine/threonine kinase 11, [RH, Score=216, Expect=8e-66]} {Mouse: ENSMUSG00000003068, Stk11, serine/threonine kinase 11, [Score=209, Expect=3e-63]} {Dmel: FBgn0038167, Lkb1, Lkb1 kinase, [Score=213, Expect=2e-63]} {Celegans: WBGene00003919, par-4, Serine/threonine-protein kinase par-4, [RH, Score=165, Expect=2e-45]} {Smed: dd_Smed_v6_10704_0_2, dd_Smed_v6_10704_0_2, [Score=263, Expect=1e-82]} {RNA1509_35109} {RNA1310_7591.1, RNA1509_35109} {RNA1509_35109, RNA815_6830}
42. MligTC455_50322 253 5.26 Mlig455_007808, Mlig455_021090

Neo: -

Age: -

KDM4A 1.885 - - 0.959 - 0.926 -

Mlig455_007808 {REF} {Length: 2597} {TRANSSPLICED} {Pfam: JmjC domain, hydroxylase [PF02373.24, score=142.3]; jmjN domain [PF02375.19, score=32.4]} {Human: ENSG00000066135, KDM4A, lysine demethylase 4A, [Score=371, Expect=4e-117]; ENSG00000107077, KDM4C, lysine demethylase 4C, [Score=367, Expect=1e-115]; ENSG00000127663, KDM4B, lysine demethylase 4B, [Score=353, Expect=4e-110]} {Mouse: ENSMUSG00000033326, Kdm4a, lysine (K)-specific demethylase 4A, [Score=373, Expect=3e-118]; ENSMUSG00000028397, Kdm4c, lysine (K)-specific demethylase 4C, [Score=365, Expect=2e-115]} {Dmel: FBgn0053182, Kdm4B, Lysine (K)-specific demethylase 4B, [Score=361, Expect=9e-119]} {Celegans: WBGene00012982, jmjd-2, Lysine-specific demethylase 4, [Score=309, Expect=2e-95]} {Smed: dd_Smed_v6_10489_0_2, dd_Smed_v6_10489_0_2, [Score=331, Expect=3e-109]} {RNA1509_38626} {RNA1310_14809.1} {RNA815_23117}

Mlig455_021090 {REF} {Length: 2449} {TRANSSPLICED} {Pfam: JmjC domain, hydroxylase [PF02373.24, score=142.4]; jmjN domain [PF02375.19, score=32.4]} {Human: ENSG00000066135, KDM4A, lysine demethylase 4A, [Score=369, Expect=7e-117]; ENSG00000107077, KDM4C, lysine demethylase 4C, [Score=368, Expect=3e-116]; ENSG00000127663, KDM4B, lysine demethylase 4B, [Score=354, Expect=7e-111]} {Mouse: ENSMUSG00000033326, Kdm4a, lysine (K)-specific demethylase 4A, [Score=372, Expect=4e-118]; ENSMUSG00000028397, Kdm4c, lysine (K)-specific demethylase 4C, [Score=367, Expect=5e-116]} {Dmel: FBgn0053182, Kdm4B, Lysine (K)-specific demethylase 4B, [Score=361, Expect=1e-118]} {Celegans: WBGene00012982, jmjd-2, Lysine-specific demethylase 4, [Score=308, Expect=2e-95]} {Smed: dd_Smed_v6_10489_0_2, dd_Smed_v6_10489_0_2, [Score=330, Expect=8e-109]} {RNA1509_38626} {RNA1310_14809.2, RNA1509_38626} {RNA1509_38626, RNA815_23117}
43. MligTC455_09773 633 13.18 Mlig455_031595

Neo: -

Age: -

1.884 - - - - 0.929 0.955 Mlig455_031595 {REF} {Length: 1992} {RNA1509_30983} {RNA1310_27418, RNA1509_30983} {RNA1509_30983, RNA815_40613}
44. MligTC455_09637 94 1.95 Mlig455_068836

Neo: -

Age: -

Region-enriched R4: 7.544/0.00021

1.881 - - 0.930 - 0.951 - Mlig455_068836 {REF} {Length: 248} {NoTransDecoderORF} {RNA1310_39046} {RNA815_41302}
45. MligTC455_19071 245 5.1 Mlig455_015327, Mlig455_015370

Neo: -

Age: logFC(26M/2M)=-1.030

1.879 - - 0.955 - 0.924 -

Mlig455_015327 {REF} {Length: 1144} {RNA1509_45342} {RNA1310_18407} {RNA815_30771}

Mlig455_015370 {REF} {Length: 1190} {RNA1509_45342} {RNA1310_18407} {RNA815_30771}
46. MligTC455_48735 516 10.75 Mlig455_054654

Neo: Int S/G2/M

Age: -

MRPL3 1.876 - - - - 0.952 0.924 Mlig455_054654 {REF} {Length: 1407} {TRANSSPLICED} {Pfam: Ribosomal protein L3 [PF00297.24, score=41.1]} {Human: ENSG00000114686, MRPL3, mitochondrial ribosomal protein L3, [RH, Score=166, Expect=2e-47]} {Mouse: ENSMUSG00000032563, Mrpl3, mitochondrial ribosomal protein L3, [RH, Score=160, Expect=2e-45]} {Dmel: FBgn0030686, mRpL3, mitochondrial ribosomal protein L3, [RH, Score=197, Expect=2e-59]} {Celegans: WBGene00016142, mrps-18C, Putative 39S ribosomal protein L3, mitochondrial, [RH, Score=122, Expect=4e-31]} {Smed: dd_Smed_v6_2057_0_1, dd_Smed_v6_2057_0_1, [RH, Score=277, Expect=2e-90]} {RNA1509_26077} {RNA1310_23165} {RNA815_9925.1}
47. MligTC455_18198 194 4.03 Mlig455_063356

Neo: -

Age: -

1.874 - - 0.952 - - 0.922 Mlig455_063356 {REF} {Length: 2891} {NoTransDecoderORF} {RNA1509_46309} {RNA1310_39028.1} {RNA815_57356}
48. MligTC455_46704 1062 22.12 Mlig455_007999

Neo: -

Age: -

DNAJB11 1.864 - - - - 0.971 0.893 Mlig455_007999 {REF} {Length: 3215} {TRANSSPLICED} {Pfam: DnaJ domain [PF00226.33, score=93.3]} {Human: ENSG00000090520, DNAJB11, DnaJ heat shock protein family (Hsp40) member B11, [Score=85.1, Expect=9e-18]; ENSG00000147570, DNAJC5B, DnaJ heat shock protein family (Hsp40) member C5 beta, [Score=83.2, Expect=4e-18]; ENSG00000140403, DNAJA4, DnaJ heat shock protein family (Hsp40) member A4, [Score=82.0, Expect=2e-17]; ENSG00000179407, DNAJB8, DnaJ heat shock protein family (Hsp40) member B8, [Score=80.9, Expect=6e-17]} {Mouse: ENSMUSG00000090202, 4930503B20Rik, RIKEN cDNA 4930503B20 gene, [RH, Score=82.4, Expect=1e-17]} {Dmel: FBgn0004179, Csp, Cysteine string protein, [Score=79.0, Expect=1e-16]} {Celegans: WBGene00001034, dnj-16, DNaJ domain (Prokaryotic heat shock protein), [RH, Score=335, Expect=5e-113]} {Smed: dd_Smed_v6_1779_0_1, dd_Smed_v6_1779_0_1, [Score=80.1, Expect=2e-17]} {RNA1509_12015, RNA1509_14449, RNA1509_29413, RNA1509_55977} {RNA1310_24689, RNA1509_12015, RNA1509_14449, RNA1509_29413, RNA1509_55977} {RNA1509_12015, RNA1509_14449, RNA1509_29413, RNA1509_55977, RNA815_10612}
49. MligTC455_29056 214 4.46 Mlig455_005934

Neo: Int S/G2/M

Age: Up-Up-Down

1.862 - - 0.975 0.887 - - Mlig455_005934 {REF} {Length: 3571} {Mouse: ENSMUSG00000044581, 4932415D10Rik, RIKEN cDNA 4932415D10 gene, [Score=54.7, Expect=7e-07]} {RNA1509_15781} {RNA1310_3922, RNA1509_15781} {RNA1509_15781, RNA815_5825}
50. MligTC455_42488 374 7.79 Mlig455_046417

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.582

1.862 - - 0.957 - 0.905 - Mlig455_046417 {REF} {Length: 2572} {Smed: dd_Smed_v6_12856_0_1, dd_Smed_v6_12856_0_1, [RH, Score=107, Expect=4e-27]} {RNA1509_33429, RNA1509_6433} {RNA1310_24046, RNA1509_33429} {RNA1509_33429, RNA815_8453}
51. MligTC455_45817 492 10.24 Mlig455_004593, Mlig455_064772

Neo: -

Age: -

RRAD 1.857 - - 0.901 - 0.956 -

Mlig455_004593 {REF} {Length: 2289} {Pfam: Ras family [PF00071.24, score=69.4]; RsgA GTPase [PF03193.18, score=22.0]; ADP-ribosylation factor family [PF00025.23, score=20.1]} {Human: ENSG00000166592, RRAD, RRAD, Ras related glycolysis inhibitor and calcium channel regulator, [Score=81.3, Expect=6e-18]; ENSG00000164949, GEM, GTP binding protein overexpressed in skeletal muscle, [Score=78.6, Expect=4e-17]; ENSG00000139890, REM2, RRAD and GEM like GTPase 2, [Score=78.2, Expect=8e-17]} {Mouse: ENSMUSG00000031880, Rrad, Ras-related associated with diabetes, [Score=80.5, Expect=8e-18]; ENSMUSG00000028214, Gem, GTP binding protein (gene overexpressed in skeletal muscle), [Score=77.8, Expect=7e-17]; ENSMUSG00000022176, Rem2, rad and gem related GTP binding protein 2, [Score=77.8, Expect=8e-17]} {Dmel: FBgn0264753, Rgk1, Rad, Gem/Kir family member 1, [Score=107, Expect=3e-27]} {Celegans: WBGene00013124, Y52B11A.4, [Score=60.1, Expect=9e-11]} {Smed: dd_Smed_v6_11010_0_1, dd_Smed_v6_11010_0_1, [Score=130, Expect=3e-36]} {RNA1509_20692} {RNA1310_28257.1} {RNA815_21843}

Mlig455_064772 {REF} {Length: 4499} {Pfam: Ras family [PF00071.24, score=78.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=27.1]; ADP-ribosylation factor family [PF00025.23, score=23.3]; RsgA GTPase [PF03193.18, score=21.6]} {Human: ENSG00000166592, RRAD, RRAD, Ras related glycolysis inhibitor and calcium channel regulator, [Score=91.3, Expect=1e-19]; ENSG00000164949, GEM, GTP binding protein overexpressed in skeletal muscle, [Score=88.6, Expect=8e-19]} {Mouse: ENSMUSG00000031880, Rrad, Ras-related associated with diabetes, [Score=93.2, Expect=2e-20]} {Dmel: FBgn0264753, Rgk1, Rad, Gem/Kir family member 1, [RH, Score=137, Expect=8e-34]} {Celegans: WBGene00010038, rheb-1, GTP-binding protein Rheb homolog 1, [Score=73.9, Expect=6e-15]} {Smed: dd_Smed_v6_11010_0_1, dd_Smed_v6_11010_0_1, [RH, Score=170, Expect=2e-47]} {RNA1509_15087, RNA1509_20692, RNA1509_37785} {RNA1310_15968.2, RNA1509_15087, RNA1509_20692} {RNA1509_15087, RNA1509_20692, RNA815_18047}
52. MligTC455_24481 79 1.65 Mlig455_003858

Neo: -

Age: Down-Up-Down

1.855 - - - - 0.897 0.958 Mlig455_003858 {REF} {Length: 5919} {NoTransDecoderORF} {RNA1509_26670} {RNA1310_9883} {RNA815_20555}
53. MligTC455_41507 683 14.22 Mlig455_029753, Mlig455_029849

Neo: -

Age: -

Region-enriched R4: 2.180/0.02027
Region-enriched R5: 1.936/0.00260

1.852 - - - 0.884 0.968 -

Mlig455_029753 {REF} {Length: 2787} {TRANSSPLICED} {RNA1509_43940} {RNA1310_30266, RNA1509_43940} {RNA1509_43940, RNA815_27401}

Mlig455_029849 {REF} {Length: 3264} {TRANSSPLICED} {RNA1509_43940} {RNA1310_30266} {RNA815_27401}
54. MligTC455_29414 45354 944.87 Mlig455_061145

Neo: -

Age: -

Region-enriched R3: 1.920/0.01395

PRSS48 1.846 - - - - 0.894 0.952 Mlig455_061145 {REF} {Length: 916} {Pfam: Trypsin [PF00089.28, score=105.6]; Trypsin-like peptidase domain [PF13365.8, score=39.1]} {Human: ENSG00000189099, PRSS48, serine protease 48, [Score=70.9, Expect=7e-14]; ENSG00000007038, PRSS21, serine protease 21, [Score=70.5, Expect=7e-14]; ENSG00000282838, PRSS21, serine protease 21, [Score=70.5, Expect=7e-14]; ENSG00000184647, PRSS55, serine protease 55, [Score=68.2, Expect=6e-13]; ENSG00000285141, PRSS55, serine protease 55, [Score=67.8, Expect=8e-13]} {Mouse: ENSMUSG00000024116, Prss21, protease, serine 21, [Score=70.5, Expect=5e-14]; ENSMUSG00000033200, Tpsg1, tryptase gamma 1, [Score=69.3, Expect=2e-13]; ENSMUSG00000032268, Tmprss5, transmembrane protease, serine 5 (spinesin), [Score=69.3, Expect=3e-13]; ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=68.6, Expect=5e-13]; ENSMUSG00000044664, Prss42, protease, serine 42, [Score=68.6, Expect=3e-13]} {Dmel: FBgn0042098, CG18735, [Score=67.8, Expect=5e-13]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [Score=58.5, Expect=4e-10]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [Score=97.1, Expect=1e-24]} {RNA1509_159, RNA1509_249, RNA1509_35} {RNA1310_40896, RNA1509_159, RNA1509_249, RNA1509_35} {RNA1509_159, RNA1509_249, RNA1509_35, RNA815_18704}
55. MligTC455_29415 45153 940.68 Mlig455_061156

Neo: -

Age: -

Region-enriched R3: 1.890/0.01673

PRSS48 1.846 - - - - 0.894 0.952 Mlig455_061156 {REF} {Length: 957} {Pfam: Trypsin [PF00089.28, score=105.6]; Trypsin-like peptidase domain [PF13365.8, score=39.1]} {Human: ENSG00000189099, PRSS48, serine protease 48, [Score=70.9, Expect=7e-14]; ENSG00000007038, PRSS21, serine protease 21, [Score=70.5, Expect=7e-14]; ENSG00000282838, PRSS21, serine protease 21, [Score=70.5, Expect=7e-14]; ENSG00000184647, PRSS55, serine protease 55, [Score=68.2, Expect=6e-13]; ENSG00000285141, PRSS55, serine protease 55, [Score=67.8, Expect=8e-13]} {Mouse: ENSMUSG00000024116, Prss21, protease, serine 21, [Score=70.5, Expect=5e-14]; ENSMUSG00000033200, Tpsg1, tryptase gamma 1, [Score=69.3, Expect=2e-13]; ENSMUSG00000032268, Tmprss5, transmembrane protease, serine 5 (spinesin), [Score=69.3, Expect=3e-13]; ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=68.6, Expect=5e-13]; ENSMUSG00000044664, Prss42, protease, serine 42, [Score=68.6, Expect=3e-13]} {Dmel: FBgn0042098, CG18735, [Score=67.8, Expect=5e-13]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [Score=58.5, Expect=4e-10]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [Score=97.1, Expect=1e-24]} {RNA1509_1470, RNA1509_249, RNA1509_28097, RNA1509_4311} {RNA1310_40896, RNA1509_1470, RNA1509_28097, RNA1509_4311} {RNA1509_1470, RNA1509_28097, RNA1509_4311, RNA815_18704}
56. MligTC455_51055 514 10.7 Mlig455_069959

Neo: -

Age: -

STARD3 1.844 - - 0.956 - - 0.888 Mlig455_069959 {REF} {Length: 2332} {TRANSSPLICED} {Pfam: Cholesterol-capturing domain [PF10457.11, score=165.3]; START domain [PF01852.21, score=85.3]} {Human: ENSG00000131748, STARD3, StAR related lipid transfer domain containing 3, [RH, Score=202, Expect=2e-59]} {Mouse: ENSMUSG00000018167, Stard3, START domain containing 3, [RH, Score=202, Expect=2e-59]} {Dmel: FBgn0035028, Start1, [RH, Score=135, Expect=2e-34]} {Celegans: WBGene00017826, tag-340, [Score=108, Expect=1e-25]} {Smed: dd_Smed_v6_8800_0_1, dd_Smed_v6_8800_0_1, [RH, Score=156, Expect=1e-42]} {RNA1509_19658} {RNA1310_9573.1} {RNA815_3520}
57. MligTC455_49735 313 6.53 Mlig455_011131

Neo: Int S/G2/M

Age: -

NAA35 1.841 - - 0.962 0.879 - - Mlig455_011131 {REF} {Length: 7936} {TRANSSPLICED} {Pfam: Mak10 subunit, NatC N(alpha)-terminal acetyltransferase [PF04112.15, score=54.4]} {Human: ENSG00000135040, NAA35, N(alpha)-acetyltransferase 35, NatC auxiliary subunit, [RH, Score=222, Expect=9e-62]} {Mouse: ENSMUSG00000021555, Naa35, N(alpha)-acetyltransferase 35, NatC auxiliary subunit, [RH, Score=219, Expect=1e-60]} {Dmel: FBgn0034982, Naa35, N(alpha)-acetyltransferase 35, [RH, Score=189, Expect=2e-50]} {Celegans: WBGene00020719, natc-1, N-alpha-AcetylTransferase C complex subunit, [Score=49.7, Expect=8e-06]} {Smed: dd_Smed_v6_7606_0_1, dd_Smed_v6_7606_0_1, [RH, Score=249, Expect=4e-72]} {RNA1509_10746} {RNA1310_3968, RNA1509_10746} {RNA1509_10746, RNA815_6081}
58. MligTC455_29413 45163 940.9 Mlig455_011411

Neo: -

Age: Down-Up-Up

Region-enriched R3: 1.888/0.01789

PRSS48 1.84 - - - - 0.889 0.951 Mlig455_011411 {REF} {Length: 912} {Pfam: Trypsin [PF00089.28, score=106.2]; Trypsin-like peptidase domain [PF13365.8, score=39.3]} {Human: ENSG00000189099, PRSS48, serine protease 48, [Score=70.1, Expect=1e-13]; ENSG00000007038, PRSS21, serine protease 21, [Score=69.3, Expect=2e-13]; ENSG00000282838, PRSS21, serine protease 21, [Score=69.3, Expect=2e-13]; ENSG00000184647, PRSS55, serine protease 55, [Score=67.0, Expect=1e-12]; ENSG00000285141, PRSS55, serine protease 55, [Score=67.0, Expect=2e-12]} {Mouse: ENSMUSG00000044664, Prss42, protease, serine 42, [Score=71.2, Expect=4e-14]; ENSMUSG00000024116, Prss21, protease, serine 21, [Score=70.9, Expect=5e-14]; ENSMUSG00000033200, Tpsg1, tryptase gamma 1, [Score=68.6, Expect=3e-13]; ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=68.2, Expect=6e-13]} {Dmel: FBgn0042098, CG18735, [Score=67.8, Expect=4e-13]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [Score=57.4, Expect=1e-09]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [Score=95.1, Expect=5e-24]} {RNA1509_28266, RNA1509_497} {RNA1310_40896, RNA1509_28266, RNA1509_497} {RNA1509_28266, RNA1509_497, RNA815_18704}
59. MligTC455_45120 345 7.18 Mlig455_064703

Neo: -

Age: logFC(26M/2M)=-0.394

CFAP61 1.84 - - 0.884 - - 0.956 Mlig455_064703 {REF} {Length: 4442} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4821) [PF16092.7, score=291.8]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=33.7]} {Human: ENSG00000089101, CFAP61, cilia and flagella associated protein 61, [RH, Score=1009, Expect=0.0]} {Mouse: ENSMUSG00000037143, Cfap61, cilia and flagella associated protein 61, [RH, Score=1006, Expect=0.0]} {Dmel: FBgn0050268, CG30268, [RH, Score=112, Expect=1e-24]} {Smed: dd_Smed_v6_4908_0_1, dd_Smed_v6_4908_0_1, [RH, Score=781, Expect=0.0]} {RNA1509_1314} {RNA1310_1812.1, RNA1509_1314} {RNA1509_1314, RNA815_503}
60. MligTC455_52152 187 3.9 Mlig455_024548

Neo: -

Age: Down-Up-Down

ABHD17B 1.84 - - 0.967 0.873 - - Mlig455_024548 {REF} {Length: 3595} {TRANSSPLICED} {Pfam: Serine aminopeptidase, S33 [PF12146.10, score=51.0]; alpha/beta hydrolase fold [PF00561.22, score=29.3]; Alpha/beta hydrolase family [PF12697.9, score=28.2]; Prolyl oligopeptidase family [PF00326.23, score=19.2]} {Human: ENSG00000107362, ABHD17B, abhydrolase domain containing 17B, [RH, Score=382, Expect=1e-133]; ENSG00000136379, ABHD17C, abhydrolase domain containing 17C, [RH, Score=377, Expect=3e-131]; ENSG00000129968, ABHD17A, abhydrolase domain containing 17A, [RH, Score=375, Expect=2e-130]} {Mouse: ENSMUSG00000038459, Abhd17c, abhydrolase domain containing 17C, [RH, Score=382, Expect=2e-133]; ENSMUSG00000047368, Abhd17b, abhydrolase domain containing 17B, [RH, Score=381, Expect=9e-134]; ENSMUSG00000003346, Abhd17a, abhydrolase domain containing 17A, [RH, Score=369, Expect=3e-128]} {Dmel: FBgn0053096, CG33096, [RH, Score=362, Expect=3e-126]} {Celegans: WBGene00045192, aho-3, [RH, Score=339, Expect=1e-116]} {Smed: dd_Smed_v6_8263_0_1, dd_Smed_v6_8263_0_1, [RH, Score=317, Expect=5e-108]} {RNA1509_8855} {RNA1310_4289.1, RNA1509_8855} {RNA1509_8855, RNA815_12927}
61. MligTC455_38979 1154 24.04 Mlig455_045102

Neo: Neoblast

Age: -

AHSA1 1.839 - - 0.952 0.887 - - Mlig455_045102 {REF} {Length: 2273} {TRANSSPLICED} {Pfam: Activator of Hsp90 ATPase, N-terminal [PF09229.13, score=115.5]; Activator of Hsp90 ATPase homolog 1-like protein [PF08327.13, score=79.1]} {Human: ENSG00000100591, AHSA1, activator of HSP90 ATPase activity 1, [RH, Score=313, Expect=7e-105]} {Mouse: ENSMUSG00000021037, Ahsa1, AHA1, activator of heat shock protein ATPase 1, [RH, Score=308, Expect=2e-103]} {Dmel: FBgn0032961, CG1416, [RH, Score=303, Expect=2e-101]} {Celegans: WBGene00007235, C01G10.8, [RH, Score=249, Expect=2e-80]} {Smed: dd_Smed_v6_2497_0_1, dd_Smed_v6_2497_0_1, [RH, Score=333, Expect=3e-113]} {RNA1509_27525, RNA1509_39897, RNA1509_51706, RNA1509_5354} {RNA1310_19210.1, RNA1509_27525, RNA1509_39897, RNA1509_51706, RNA1509_5354} {RNA1509_27525, RNA1509_39897, RNA1509_51706, RNA1509_5354, RNA815_6399}
62. MligTC455_06035 315 6.55 Mlig455_033343

Neo: -

Age: -

1.835 - - 0.969 - 0.866 - Mlig455_033343 {REF} {Length: 515} {NoTransDecoderORF} {RNA1509_40958} {RNA1310_25752.1} {RNA815_37868}
63. MligTC455_23555 418 8.71 Mlig455_013595

Neo: -

Age: -

DNAJC4 1.834 - - - 0.858 0.976 - Mlig455_013595 {REF} {Length: 2081} {TRANSSPLICED} {Pfam: DnaJ domain [PF00226.33, score=67.2]} {Human: ENSG00000110011, DNAJC4, DnaJ heat shock protein family (Hsp40) member C4, [RH, Score=67.4, Expect=5e-13]; ENSG00000176410, DNAJC30, DnaJ heat shock protein family (Hsp40) member C30, [RH, Score=64.7, Expect=4e-12]} {Mouse: ENSMUSG00000014905, Dnajb9, DnaJ heat shock protein family (Hsp40) member B9, [Score=67.4, Expect=3e-13]} {Dmel: FBgn0037544, CG11035, [Score=65.5, Expect=1e-12]} {Celegans: WBGene00001022, dnj-4, DNaJ domain (Prokaryotic heat shock protein), [RH, Score=58.9, Expect=3e-10]} {Smed: dd_Smed_v6_3393_0_1, dd_Smed_v6_3393_0_1, [RH, Score=72.0, Expect=1e-15]} {RNA1509_17877, RNA1509_20487, RNA1509_27055, RNA1509_35237, RNA1509_47036, RNA1509_54606, RNA1509_56854} {RNA1310_22951, RNA1509_17877, RNA1509_20487, RNA1509_27055, RNA1509_35237, RNA1509_47036, RNA1509_54606, RNA1509_56854} {RNA1509_17877, RNA1509_20487, RNA1509_27055, RNA1509_35237, RNA1509_47036, RNA1509_54606, RNA1509_56854, RNA815_9786}
64. MligTC455_26084 103 2.14 Mlig455_001492, Mlig455_001511

Neo: -

Age: logFC(26M/2M)=0.705

Region-enriched R4: 4.416/0.01109
Region-enriched R3: 3.272/0.03772

STIM2 1.828 - - - 0.867 - 0.961

Mlig455_001492 {REF} {Length: 2953} {TRANSSPLICED} {Pfam: STIM1 Orai1-activating region [PF16533.7, score=74.1]} {Human: ENSG00000109689, STIM2, stromal interaction molecule 2, [Score=119, Expect=3e-27]} {Mouse: ENSMUSG00000039156, Stim2, stromal interaction molecule 2, [Score=119, Expect=2e-27]} {RNA1509_56255} {RNA1310_24241} {RNA815_19275}

Mlig455_001511 {REF} {Length: 4232} {TRANSSPLICED} {Pfam: STIM1 Orai1-activating region [PF16533.7, score=73.2]} {Human: ENSG00000109689, STIM2, stromal interaction molecule 2, [Score=66.6, Expect=2e-10]} {Mouse: ENSMUSG00000039156, Stim2, stromal interaction molecule 2, [Score=66.2, Expect=2e-10]} {RNA1509_56255} {RNA1310_24241} {RNA815_19275}
65. MligTC455_50933 280 5.83 Mlig455_011495

Neo: -

Age: Down-Down-Up

1.828 - - 0.978 - 0.850 - Mlig455_011495 {REF} {Length: 3671} {TRANSSPLICED} {RNA1509_11429} {RNA1310_2886.1} {RNA815_8254}
66. MligTC455_30100 658 13.71 Mlig455_013076

Neo: -

Age: -

1.826 - - - 0.864 0.962 - Mlig455_013076 {REF} {Length: 1614} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_16891, RNA1509_42687, RNA1509_46285} {RNA1310_29962, RNA1509_42687, RNA1509_46285} {RNA1509_42687, RNA1509_46285, RNA815_14826}
67. MligTC455_53775 449 9.35 Mlig455_012089

Neo: Int S/G2/M

Age: -

1.817 - - 0.952 0.865 - - Mlig455_012089 {REF} {Length: 2012} {NoTransDecoderORF} {RNA1509_35827} {RNA1310_45584} {RNA815_12875}
68. MligTC455_38964 433 9.02 Mlig455_049691

Neo: Int S/G2/M

Age: Down-Up-Down

SRSF11 1.815 - - 0.970 - - 0.845 Mlig455_049691 {REF} {Length: 4541} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=31.1]} {Human: ENSG00000116754, SRSF11, serine and arginine rich splicing factor 11, [RH, Score=99.4, Expect=2e-21]} {Mouse: ENSMUSG00000032621, Srek1, splicing regulatory glutamine/lysine-rich protein 1, [Score=165, Expect=1e-43]} {Dmel: FBgn0024285, Srp54, [RH, Score=156, Expect=5e-41]} {Celegans: WBGene00004704, rsp-7, Probable splicing factor, arginine/serine-rich 7, [Score=105, Expect=4e-24]} {Smed: dd_Smed_v6_5957_0_1, dd_Smed_v6_5957_0_1, [RH, Score=145, Expect=4e-40]} {RNA1509_27257, RNA1509_48641} {RNA1310_15393, RNA1509_27257, RNA1509_48641} {RNA1509_27257, RNA1509_48641, RNA815_14196}
69. MligTC455_20935 333 6.94 Mlig455_022795

Neo: -

Age: Down-Up-Down

1.813 - - 0.974 - - 0.839 Mlig455_022795 {REF} {Length: 1130} {NoTransDecoderORF} {RNA1509_54238} {RNA1310_21943.2} {RNA815_11106.1}
70. MligTC455_21148 332 6.93 Mlig455_039576

Neo: -

Age: -

Region-enriched R4: 1.722/0.01281

1.812 - - 0.960 0.852 - - Mlig455_039576 {REF} {Length: 4764} {TRANSSPLICED} {tRNA: Glu(TTC), score=70.7} {Pfam: Mediator complex subunit 25 von Willebrand factor type A [PF11265.10, score=33.5]} {Smed: dd_Smed_v6_10165_0_1, dd_Smed_v6_10165_0_1, [RH, Score=89.4, Expect=3e-18]} {RNA1509_59973} {RNA1310_5708, RNA1509_59973} {RNA1509_59973, RNA815_16377}
71. MligTC455_21659 118 2.46 Mlig455_011541

Neo: -

Age: -

1.809 - - - 0.850 0.959 - Mlig455_011541 {REF} {Length: 998} {NoTransDecoderORF} {RNA1509_32094} {RNA1310_39417} {RNA815_38074}
72. MligTC455_50425 1754 36.55 Mlig455_021985, Mlig455_031763, Mlig455_051833, Mlig455_063612

Neo: -

Age: Down-Up-Down

1.804 - - 0.975 - - 0.829

Mlig455_021985 {REF} {Length: 394} {TRANSSPLICED} {RNA1509_59895} {RNA1310_900.2} {RNA815_1698.1}

Mlig455_031763 {REF} {Length: 391} {TRANSSPLICED} {RNA1509_59895} {RNA1310_900.2} {RNA815_1698.1}

Mlig455_051833 {REF} {Length: 498} {TRANSSPLICED} {RNA1509_43937} {RNA1310_900.2} {RNA815_1698.1}

Mlig455_063612 {REF} {Length: 710} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_43937} {RNA1310_145253} {RNA815_1698.1}
73. MligTC455_19098 140 2.92 Mlig455_025228, Mlig455_025251

Neo: -

Age: Up-Down-Up

Region-enriched R2: 3.060/0.04934

DAXX 1.802 - - 0.955 0.847 - -

Mlig455_025228 {REF} {Length: 5839} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=46.0]} {Human: ENSG00000227046, DAXX, death domain associated protein, [Score=77.0, Expect=1e-13]; ENSG00000206279, DAXX, death domain associated protein, [Score=77.0, Expect=1e-13]; ENSG00000206206, DAXX, death domain associated protein, [Score=77.0, Expect=1e-13]; ENSG00000204209, DAXX, death domain associated protein, [Score=77.0, Expect=1e-13]; ENSG00000231617, DAXX, death domain associated protein, [Score=77.0, Expect=1e-13]} {Mouse: ENSMUSG00000002307, Daxx, Fas death domain-associated protein, [Score=84.0, Expect=6e-16]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=68.2, Expect=2e-11]} {Celegans: WBGene00010986, sprr-1, Sex Peptide Receptor (Drosophila) Related, [Score=56.2, Expect=1e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=222, Expect=1e-63]} {RNA1509_25153} {RNA1310_7064.1} {RNA815_18101}

Mlig455_025251 {REF} {Length: 3683} {Pfam: Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=18.7]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [Score=159, Expect=4e-44]} {RNA1509_60180} {RNA1310_18827} {RNA815_22334}
74. MligTC455_37986 195 4.07 Mlig455_050882

Neo: -

Age: -

TTC29 1.802 - - - - 0.968 0.834 Mlig455_050882 {REF} {Length: 1992} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=49.0]; Tetratricopeptide repeat [PF00515.30, score=36.1]; Tetratricopeptide repeat [PF13176.8, score=31.2]; Tetratricopeptide repeat [PF13432.8, score=22.1]; Tetratricopeptide repeat [PF07719.19, score=18.9]; Tetratricopeptide repeat [PF13181.8, score=18.7]} {Human: ENSG00000137473, TTC29, tetratricopeptide repeat domain 29, [Score=207, Expect=8e-61]} {Mouse: ENSMUSG00000037101, Ttc29, tetratricopeptide repeat domain 29, [Score=213, Expect=3e-63]} {Smed: dd_Smed_v6_9158_0_2, dd_Smed_v6_9158_0_2, [Score=289, Expect=2e-92]} {RNA1509_38793} {RNA1310_12639.1} {RNA815_4532}
75. MligTC455_43403 347 7.22 Mlig455_015913, Mlig455_059672

Neo: -

Age: Down-Up-Down

1.802 - - - - 0.954 0.848

Mlig455_015913 {REF} {Length: 2147} {NoTransDecoderORF} {RNA1509_4496} {RNA1310_3148.1} {RNA815_3879}

Mlig455_059672 {REF} {Length: 746} {NoTransDecoderORF} {RNA1509_42088, RNA1509_4496} {RNA1310_3148.1, RNA1509_42088} {RNA1509_42088, RNA815_3879}
76. MligTC455_43579 278 5.8 Mlig455_063153

Neo: -

Age: -

LANCL3 1.795 - - - 0.829 0.966 - Mlig455_063153 {REF} {Length: 2520} {TRANSSPLICED} {Pfam: Lanthionine synthetase C-like protein [PF05147.15, score=156.2]} {Human: ENSG00000147036, LANCL3, LanC like 3, [RH, Score=225, Expect=1e-68]} {Mouse: ENSMUSG00000047344, Lancl3, LanC lantibiotic synthetase component C-like 3 (bacterial), [RH, Score=220, Expect=6e-67]} {Dmel: FBgn0027498, CG2061, [RH, Score=200, Expect=3e-59]} {Smed: dd_Smed_v6_10666_0_2, dd_Smed_v6_10666_0_2, [Score=155, Expect=7e-43]} {RNA1509_25336, RNA1509_27502} {RNA1310_17817.2, RNA1509_25336, RNA1509_27502} {RNA1509_25336, RNA1509_27502, RNA815_8500}
77. MligTC455_49328 397 8.28 Mlig455_024822

Neo: -

Age: Down-Up-Up

SARNP 1.793 - - 0.966 0.827 - - Mlig455_024822 {REF} {Length: 2186} {TRANSSPLICED} {Pfam: Tho1/MOS11 C-terminal domain [PF18592.3, score=39.7]; SAP domain [PF02037.29, score=38.8]; SAP domain-containing new25 [PF18953.2, score=27.2]} {Human: ENSG00000205323, SARNP, SAP domain containing ribonucleoprotein, [Score=50.1, Expect=2e-06]} {Mouse: ENSMUSG00000078427, Sarnp, SAP domain containing ribonucleoprotein, [Score=48.5, Expect=3e-06]; ENSMUSG00000051255, Gm6563, predicted pseudogene 6563, [Score=48.5, Expect=3e-06]} {Smed: dd_Smed_v6_2297_0_1, dd_Smed_v6_2297_0_1, [Score=64.7, Expect=9e-12]} {RNA1509_12023} {RNA1310_24293, RNA1509_12023} {RNA1509_12023, RNA815_8482}
78. MligTC455_42683 399 8.31 Mlig455_065293

Neo: -

Age: -

Region-enriched R4: 2.217/0.01915

SLC22A3 1.789 - - 0.969 0.820 - - Mlig455_065293 {REF} {Length: 5681} {TRANSSPLICED} {Pfam: Sugar (and other) transporter [PF00083.26, score=106.5]; Major Facilitator Superfamily [PF07690.18, score=102.9]} {Human: ENSG00000146477, SLC22A3, solute carrier family 22 member 3, [RH, Score=310, Expect=3e-98]; ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [RH, Score=308, Expect=1e-97]; ENSG00000172940, SLC22A13, solute carrier family 22 member 13, [RH, Score=297, Expect=3e-93]} {Mouse: ENSMUSG00000023828, Slc22a3, solute carrier family 22 (organic cation transporter), member 3, [RH, Score=322, Expect=3e-103]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [RH, Score=377, Expect=1e-124]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [RH, Score=289, Expect=3e-90]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [RH, Score=261, Expect=4e-80]} {RNA1509_7807} {RNA1310_8912, RNA1509_7807} {RNA1509_7807, RNA815_6870}
79. MligTC455_27933 109 2.27 Mlig455_062805

Neo: -

Age: logFC(26M/2M)=0.852

MYLK 1.788 - - 0.964 - 0.824 - Mlig455_062805 {REF} {Length: 5619} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=190.4]; Protein kinase domain [PF00069.27, score=143.5]; Immunoglobulin domain [PF13927.8, score=121.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=80.8]; Immunoglobulin domain [PF13895.8, score=52.2]; Immunoglobulin domain [PF00047.27, score=51.8]; Immunoglobulin V-set domain [PF07686.19, score=38.3]; ABC1 atypical kinase-like domain [PF03109.18, score=21.5]} {Human: ENSG00000065534, MYLK, myosin light chain kinase, [Score=184, Expect=7e-47]; ENSG00000140795, MYLK3, myosin light chain kinase 3, [Score=176, Expect=6e-45]} {Mouse: ENSMUSG00000051747, Ttn, titin, [Score=187, Expect=6e-48]; ENSMUSG00000022836, Mylk, myosin, light polypeptide kinase, [Score=184, Expect=4e-47]} {Dmel: FBgn0005666, bt, bent, [Score=197, Expect=4e-51]} {Celegans: WBGene00006759, unc-22, Twitchin, [Score=216, Expect=1e-57]} {Smed: dd_Smed_v6_2544_0_1, dd_Smed_v6_2544_0_1, [Score=184, Expect=2e-47]} {RNA1509_411} {RNA1310_1.1} {RNA815_0}
80. MligTC455_34335 663 13.81 Mlig455_056712

Neo: -

Age: -

Region-enriched R3: 1.005/0.04018

SLC27A1 1.788 - - - 0.838 0.950 - Mlig455_056712 {REF} {Length: 4873} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=249.3]; AMP-binding enzyme C-terminal domain [PF13193.8, score=37.0]} {Human: ENSG00000130304, SLC27A1, solute carrier family 27 member 1, [RH, Score=591, Expect=0.0]} {Mouse: ENSMUSG00000059316, Slc27a4, solute carrier family 27 (fatty acid transporter), member 4, [RH, Score=602, Expect=0.0]; ENSMUSG00000031808, Slc27a1, solute carrier family 27 (fatty acid transporter), member 1, [RH, Score=596, Expect=0.0]} {Dmel: FBgn0265187, CG44252, [RH, Score=565, Expect=0.0]} {Celegans: WBGene00017012, acs-22, Fatty Acid CoA Synthetase family, [RH, Score=478, Expect=3e-161]} {Smed: dd_Smed_v6_4057_0_1, dd_Smed_v6_4057_0_1, [RH, Score=617, Expect=0.0]} {RNA1509_11133, RNA1509_25949, RNA1509_38088, RNA1509_45315, RNA1509_9470} {RNA1310_11936, RNA1509_11133, RNA1509_25949, RNA1509_38088, RNA1509_45315, RNA1509_9470} {RNA1509_11133, RNA1509_25949, RNA1509_38088, RNA1509_45315, RNA1509_9470, RNA815_4353}
81. MligTC455_37352 210 4.37 Mlig455_012059

Neo: Int S/G2/M

Age: -

RNASEH2A 1.788 - - - 0.817 0.971 - Mlig455_012059 {REF} {Length: 1775} {TRANSSPLICED} {Pfam: Ribonuclease HII [PF01351.20, score=153.5]} {Human: ENSG00000104889, RNASEH2A, ribonuclease H2 subunit A, [RH, Score=232, Expect=4e-74]} {Mouse: ENSMUSG00000052926, Rnaseh2a, ribonuclease H2, large subunit, [RH, Score=234, Expect=5e-75]} {Dmel: FBgn0031252, CG13690, [RH, Score=226, Expect=1e-71]} {Celegans: WBGene00004383, rnh-2, Ribonuclease H2 subunit A, [RH, Score=231, Expect=3e-74]} {Smed: dd_Smed_v6_10404_0_1, dd_Smed_v6_10404_0_1, [RH, Score=261, Expect=8e-86]} {RNA1509_29004} {RNA1310_30632} {RNA815_10850}
82. MligTC455_50010 647 13.48 Mlig455_042000

Neo: -

Age: -

ARPP19 1.786 - - - - 0.954 0.832 Mlig455_042000 {REF} {Length: 1393} {TRANSSPLICED} {Pfam: cAMP-regulated phosphoprotein/endosulfine conserved region [PF04667.19, score=31.2]} {Human: ENSG00000128989, ARPP19, cAMP regulated phosphoprotein 19, [Score=67.8, Expect=4e-15]; ENSG00000143420, ENSA, endosulfine alpha, [Score=66.6, Expect=2e-14]} {Mouse: ENSMUSG00000007656, Arpp19, cAMP-regulated phosphoprotein 19, [Score=69.7, Expect=6e-16]} {Dmel: FBgn0061515, endos, endosulfine, [Score=50.8, Expect=8e-09]} {Smed: dd_Smed_v6_4126_0_2, dd_Smed_v6_4126_0_2, [Score=62.8, Expect=2e-13]} {RNA1509_31306, RNA1509_9409} {RNA1310_24278, RNA1509_31306, RNA1509_9409} {RNA1509_31306, RNA1509_9409, RNA815_15347.1}
83. MligTC455_22487 283 5.89 Mlig455_001081

Neo: -

Age: -

1.78 - - 0.953 - 0.827 - Mlig455_001081 {REF} {Length: 3990} {TRANSSPLICED} {Smed: dd_Smed_v6_11081_0_2, dd_Smed_v6_11081_0_2, [Score=62.0, Expect=1e-09]} {RNA1509_12629} {RNA1310_2194.1} {RNA815_7569}
84. MligTC455_35756 521 10.85 Mlig455_015265

Neo: -

Age: -

Region-enriched R5: 3.153/0.00000

1.776 - - - 0.814 - 0.962 Mlig455_015265 {REF} {Length: 2098} {RNA1509_8215} {RNA1310_9407.1} {RNA815_2518.1}
85. MligTC455_47761 494 10.28 Mlig455_063306

Neo: -

Age: -

NT5C3A 1.776 - - 0.959 0.817 - - Mlig455_063306 {REF} {Length: 2529} {TRANSSPLICED} {Pfam: Pyrimidine 5'-nucleotidase (UMPH-1) [PF05822.14, score=255.4]; haloacid dehalogenase-like hydrolase [PF12710.9, score=26.5]} {Human: ENSG00000122643, NT5C3A, 5'-nucleotidase, cytosolic IIIA, [RH, Score=234, Expect=3e-74]} {Mouse: ENSMUSG00000029780, Nt5c3, 5'-nucleotidase, cytosolic III, [RH, Score=233, Expect=4e-74]} {Dmel: FBgn0034988, cN-IIIB, cytosolic 5'-nucleotidase IIIB, [RH, Score=184, Expect=5e-55]} {Celegans: WBGene00017775, F25B5.3, Putative cytosolic 5'-nucleotidase 3, [RH, Score=176, Expect=2e-51]} {Smed: dd_Smed_v6_3196_0_2, dd_Smed_v6_3196_0_2, [RH, Score=233, Expect=9e-74]} {RNA1509_27865, RNA1509_39066, RNA1509_45325} {RNA1310_20363, RNA1509_27865, RNA1509_39066, RNA1509_45325} {RNA1509_27865, RNA1509_39066, RNA1509_45325, RNA815_5383}
86. MligTC455_52740 64 1.33 Mlig455_018659

Neo: -

Age: -

SLC25A32 1.776 - - - 0.823 0.953 - Mlig455_018659 {REF} {Length: 1784} {TRANSSPLICED} {Pfam: Mitochondrial carrier protein [PF00153.29, score=207.4]} {Human: ENSG00000164933, SLC25A32, solute carrier family 25 member 32, [RH, Score=317, Expect=1e-107]} {Mouse: ENSMUSG00000107007, Slc25a32, solute carrier family 25, member 32, [RH, Score=308, Expect=5e-104]; ENSMUSG00000022299, Slc25a32, solute carrier family 25, member 32, [RH, Score=308, Expect=5e-104]} {Dmel: FBgn0033391, CG8026, [RH, Score=319, Expect=2e-108]} {Celegans: WBGene00010459, slc-25A32, SLC (SoLute Carrier) homolog, [RH, Score=199, Expect=4e-62]} {Smed: dd_Smed_v6_4728_0_1, dd_Smed_v6_4728_0_1, [RH, Score=308, Expect=2e-104]} {RNA1509_25677} {RNA1310_32072, RNA1509_25677} {RNA1509_25677, RNA815_17036}
87. MligTC455_51810 292 6.09 Mlig455_055914

Neo: -

Age: logFC(26M/2M)=0.322

RAB29 1.77 - - - 0.814 0.956 - Mlig455_055914 {REF} {Length: 1941} {Pfam: Ras family [PF00071.24, score=68.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=19.6]} {Human: ENSG00000117280, RAB29, RAB29, member RAS oncogene family, [RH, Score=123, Expect=3e-36]} {Mouse: ENSMUSG00000019832, Rab32, RAB32, member RAS oncogene family, [Score=127, Expect=9e-37]} {Dmel: FBgn0002567, Rab32, [Score=112, Expect=3e-31]} {Celegans: WBGene00011083, glo-1, Gut granule LOss; Rab GTPase GLO-1, [Score=106, Expect=4e-29]} {Smed: dd_Smed_v6_2915_0_1, dd_Smed_v6_2915_0_1, [Score=134, Expect=3e-40]} {RNA1509_54279} {RNA1310_15012} {RNA815_20567}
88. MligTC455_12881 431 8.97 Mlig455_069109

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.318

CYLD 1.769 - - - 0.802 0.967 - Mlig455_069109 {REF} {Length: 5402} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=29.6]} {Human: ENSG00000083799, CYLD, CYLD lysine 63 deubiquitinase, [RH, Score=296, Expect=2e-86]} {Mouse: ENSMUSG00000036712, Cyld, CYLD lysine 63 deubiquitinase, [Score=287, Expect=3e-83]} {Dmel: FBgn0032210, CYLD, Cylindromatosis, [RH, Score=323, Expect=2e-99]} {Celegans: WBGene00009594, cyld-1, CYLinDromatosis (Human disease gene) homolog, [RH, Score=210, Expect=1e-56]} {Smed: dd_Smed_v6_3043_0_1, dd_Smed_v6_3043_0_1, [RH, Score=158, Expect=8e-40]} {RNA1509_18711, RNA1509_19340, RNA1509_34756, RNA1509_35847} {RNA1310_5613.1, RNA1509_19340, RNA1509_34756, RNA1509_35847} {RNA1509_19340, RNA1509_34756, RNA1509_35847, RNA815_1700}
89. MligTC455_53653 536 11.18 Mlig455_059297

Neo: Int S/G2/M

Age: -

SETD2 1.766 - - - 0.802 0.964 - Mlig455_059297 {REF} {Length: 4434} {TRANSSPLICED} {Pfam: SET domain [PF00856.30, score=73.1]; AWS domain [PF17907.3, score=30.0]} {Human: ENSG00000181555, SETD2, SET domain containing 2, [RH, Score=234, Expect=6e-62]} {Mouse: ENSMUSG00000044791, Setd2, SET domain containing 2, [RH, Score=234, Expect=4e-62]} {Dmel: FBgn0030486, Set2, SET domain containing 2, [RH, Score=198, Expect=7e-51]} {Celegans: WBGene00016603, met-1, Histone-lysine N-methyltransferase, [RH, Score=182, Expect=3e-46]} {Smed: dd_Smed_v6_10742_0_1, dd_Smed_v6_10742_0_1, [RH, Score=261, Expect=5e-71]} {RNA1509_9722} {RNA1310_4575.1} {RNA815_10111}
90. MligTC455_39912 126 2.62 Mlig455_005780

Neo: -

Age: logFC(26M/2M)=0.297

IST1 1.765 - - 0.971 0.794 - - Mlig455_005780 {REF} {Length: 2185} {Pfam: Regulator of Vps4 activity in the MVB pathway [PF03398.16, score=202.0]} {Human: ENSG00000182149, IST1, IST1, ESCRT-III associated factor, [RH, Score=287, Expect=1e-95]} {Mouse: ENSMUSG00000031729, Ist1, increased sodium tolerance 1 homolog (yeast), [RH, Score=266, Expect=3e-87]} {Dmel: FBgn0035715, CG10103, [RH, Score=248, Expect=2e-79]} {Celegans: WBGene00010736, istr-1, Increased Sodium Tolerance Related, [RH, Score=244, Expect=6e-78]} {Smed: dd_Smed_v6_2006_0_1, dd_Smed_v6_2006_0_1, [RH, Score=287, Expect=2e-96]} {RNA1509_4021} {RNA1310_50949.1} {RNA815_14394.1}
91. MligTC455_47187 163 3.4 Mlig455_065053

Neo: -

Age: -

Region-enriched R2: 3.157/0.01854

1.764 - - 0.959 - 0.805 - Mlig455_065053 {REF} {Length: 3229} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=45.0]} {Smed: dd_Smed_v6_21592_0_1, dd_Smed_v6_21592_0_1, [RH, Score=63.2, Expect=8e-11]} {RNA1509_28827} {RNA1310_43256} {RNA815_16925}
92. MligTC455_03333 186 3.87 Mlig455_044056

Neo: -

Age: -

CLK2 1.758 - - - 0.799 0.959 - Mlig455_044056 {REF} {Length: 4751} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=146.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=66.3]} {Human: ENSG00000261893, CLK2, CDC like kinase 2, [Score=395, Expect=2e-131]; ENSG00000176444, CLK2, CDC like kinase 2, [Score=395, Expect=2e-131]} {Mouse: ENSMUSG00000068917, Clk2, CDC-like kinase 2, [Score=394, Expect=6e-131]} {Dmel: FBgn0265998, Doa, Darkener of apricot, [Score=388, Expect=1e-128]} {Celegans: WBGene00006517, madd-3, [Score=365, Expect=2e-121]} {Smed: dd_Smed_v6_8461_0_1, dd_Smed_v6_8461_0_1, [Score=392, Expect=3e-127]} {RNA1509_10891, RNA1509_48966, RNA1509_56038} {RNA1310_14739.1, RNA1509_10891, RNA1509_48966, RNA1509_56038} {RNA1509_10891, RNA1509_48966, RNA1509_56038, RNA815_4478}
93. MligTC455_06036 344 7.17 Mlig455_033356

Neo: -

Age: -

PRKAG2 1.758 - - 0.967 - 0.791 - Mlig455_033356 {REF} {Length: 3376} {Pfam: CBS domain [PF00571.30, score=98.5]} {Human: ENSG00000106617, PRKAG2, protein kinase AMP-activated non-catalytic subunit gamma 2, [Score=340, Expect=1e-114]; ENSG00000181929, PRKAG1, protein kinase AMP-activated non-catalytic subunit gamma 1, [Score=340, Expect=2e-114]} {Mouse: ENSMUSG00000028944, Prkag2, protein kinase, AMP-activated, gamma 2 non-catalytic subunit, [Score=346, Expect=7e-114]; ENSMUSG00000067713, Prkag1, protein kinase, AMP-activated, gamma 1 non-catalytic subunit, [Score=339, Expect=1e-114]} {Dmel: FBgn0264357, SNF4Agamma, SNF4/AMP-activated protein kinase gamma subunit, [Score=353, Expect=3e-117]} {Celegans: WBGene00013732, aakg-1, AMP-Activated protein Kinase Gamma subunit, [Score=289, Expect=4e-93]} {Smed: dd_Smed_v6_4877_0_1, dd_Smed_v6_4877_0_1, [Score=298, Expect=2e-98]} {RNA1509_48129} {RNA1310_7406.2} {RNA815_1861}
94. MligTC455_45193 449 9.36 Mlig455_057071

Neo: -

Age: -

M6PR 1.757 0.784 - - - 0.973 - Mlig455_057071 {REF} {Length: 1817} {TRANSSPLICED} {Pfam: Mannose-6-phosphate receptor [PF02157.17, score=95.2]} {Human: ENSG00000003056, M6PR, mannose-6-phosphate receptor, cation dependent, [RH, Score=94.4, Expect=2e-22]} {Mouse: ENSMUSG00000007458, M6pr, mannose-6-phosphate receptor, cation dependent, [RH, Score=91.7, Expect=9e-22]} {Smed: dd_Smed_v6_1365_0_1, dd_Smed_v6_1365_0_1, [Score=73.6, Expect=2e-15]} {RNA1509_16409} {RNA1310_31108} {RNA815_14525}
95. MligTC455_19099 94 1.95 Mlig455_025635

Neo: -

Age: -

TRHR 1.756 - - 0.953 0.803 - - Mlig455_025635 {REF} {Length: 3815} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=39.5]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=18.8]} {Human: ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=60.8, Expect=2e-09]} {Mouse: ENSMUSG00000038760, Trhr, thyrotropin releasing hormone receptor, [Score=58.9, Expect=6e-09]; ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=57.8, Expect=1e-08]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=65.9, Expect=3e-11]} {Celegans: WBGene00019445, frpr-12, FMRFamide Peptide Receptor family, [Score=56.2, Expect=2e-08]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=223, Expect=8e-68]} {RNA1509_60180} {RNA1310_18827} {RNA815_22334}
96. MligTC455_35800 5263 109.65 Mlig455_059846

Neo: -

Age: Down-Up-Down

UBE2D2 1.755 - - - 0.795 0.960 - Mlig455_059846 {REF} {Length: 1646} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=178.7]} {Human: ENSG00000131508, UBE2D2, ubiquitin conjugating enzyme E2 D2, [RH, Score=288, Expect=2e-101]; ENSG00000109332, UBE2D3, ubiquitin conjugating enzyme E2 D3, [RH, Score=288, Expect=2e-101]; ENSG00000078967, UBE2D4, ubiquitin conjugating enzyme E2 D4 (putative), [RH, Score=283, Expect=2e-99]; ENSG00000072401, UBE2D1, ubiquitin conjugating enzyme E2 D1, [RH, Score=279, Expect=6e-98]} {Mouse: ENSMUSG00000078578, Ube2d3, ubiquitin-conjugating enzyme E2D 3, [RH, Score=288, Expect=2e-101]; ENSMUSG00000091896, Ube2d2a, ubiquitin-conjugating enzyme E2D 2A, [RH, Score=288, Expect=1e-101]; ENSMUSG00000019927, Ube2d1, ubiquitin-conjugating enzyme E2D 1, [RH, Score=279, Expect=4e-98]} {Dmel: FBgn0011217, eff, effete, [RH, Score=299, Expect=4e-106]} {Celegans: WBGene00002344, let-70, Ubiquitin-conjugating enzyme E2 2, [RH, Score=296, Expect=4e-105]} {Smed: dd_Smed_v6_153_0_1, dd_Smed_v6_153_0_1, [RH, Score=265, Expect=7e-93]} {RNA1509_49403, RNA1509_773} {RNA1310_50461, RNA1509_49403} {RNA1509_49403, RNA815_14659}
97. MligTC455_50548 651 13.56 Mlig455_039553, Mlig455_051358

Neo: -

Age: logFC(26M/2M)=0.261

MRI1 1.755 0.801 - - - 0.954 -

Mlig455_039553 {REF} {Length: 2475} {TRANSSPLICED} {Pfam: Initiation factor 2 subunit family [PF01008.19, score=256.7]} {Human: ENSG00000037757, MRI1, methylthioribose-1-phosphate isomerase 1, [RH, Score=364, Expect=2e-124]} {Mouse: ENSMUSG00000004996, Mri1, methylthioribose-1-phosphate isomerase 1, [RH, Score=355, Expect=5e-121]} {Dmel: FBgn0039849, CG11334, [RH, Score=379, Expect=1e-130]} {Celegans: WBGene00007236, C01G10.9, Methylthioribose-1-phosphate isomerase, [RH, Score=268, Expect=3e-87]} {RNA1509_13437, RNA1509_22125} {RNA1310_17445.2, RNA1509_22125} {RNA1509_22125, RNA815_10627.1}

Mlig455_051358 {REF} {Length: 2101} {TRANSSPLICED} {Pfam: Initiation factor 2 subunit family [PF01008.19, score=257.4]} {Human: ENSG00000037757, MRI1, methylthioribose-1-phosphate isomerase 1, [RH, Score=367, Expect=1e-125]} {Mouse: ENSMUSG00000004996, Mri1, methylthioribose-1-phosphate isomerase 1, [RH, Score=358, Expect=4e-122]} {Dmel: FBgn0039849, CG11334, [RH, Score=380, Expect=3e-131]} {Celegans: WBGene00007236, C01G10.9, Methylthioribose-1-phosphate isomerase, [RH, Score=270, Expect=6e-88]} {RNA1509_13437} {RNA1310_17445.2, RNA1509_13437} {RNA1509_13437, RNA815_10627.1}
98. MligTC455_45640 354 7.37 Mlig455_044849

Neo: -

Age: -

Region-enriched R4: 1.921/0.00612

NFAT5 1.753 - - - 0.800 - 0.953 Mlig455_044849 {REF} {Length: 2286} {Human: ENSG00000102908, NFAT5, nuclear factor of activated T cells 5, [Score=70.1, Expect=3e-13]} {Mouse: ENSMUSG00000003847, Nfat5, nuclear factor of activated T cells 5, [Score=71.2, Expect=8e-14]} {Dmel: FBgn0030505, NFAT, NFAT nuclear factor, [Score=64.3, Expect=1e-11]} {Smed: dd_Smed_v6_5978_0_1, dd_Smed_v6_5978_0_1, [Score=75.5, Expect=1e-15]} {RNA1509_28577} {RNA1310_61235.1} {RNA815_20233.1}
99. MligTC455_21493 859 17.89 Mlig455_059385

Neo: -

Age: Down-Down-Up

YWHAE 1.751 - - - - 0.795 0.956 Mlig455_059385 {REF} {Length: 1860} {Pfam: 14-3-3 protein [PF00244.22, score=353.7]} {Human: ENSG00000274474, YWHAE, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon, [RH, Score=392, Expect=3e-139]; ENSG00000108953, YWHAE, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon, [RH, Score=392, Expect=3e-139]} {Mouse: ENSMUSG00000020849, Ywhae, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide, [RH, Score=392, Expect=2e-139]} {Dmel: FBgn0020238, 14-3-3epsilon, [RH, Score=388, Expect=8e-138]} {Celegans: WBGene00003920, par-5, 14-3-3-like protein 1, [Score=310, Expect=3e-107]} {Smed: dd_Smed_v6_1702_0_1, dd_Smed_v6_1702_0_1, [RH, Score=360, Expect=3e-127]} {RNA1509_19788, RNA1509_2790} {RNA1310_17239.1, RNA1509_19788} {RNA1509_19788, RNA815_6314.1}
100. MligTC455_28838 84 1.75 Mlig455_007557

Neo: -

Age: -

Region-enriched R4: 3.260/0.01289
Region-enriched R5: 2.662/0.02640

1.75 - - 0.963 0.787 - - Mlig455_007557 {REF} {Length: 745} {RNA1310_66594.1} {RNA815_40011}

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