Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_49273 | 592 | 12.33 | Mlig455_048444, Mlig455_062732 | Neo: Int S/G2/M Age: - Region-enriched R4: 2.295/0.00239 |
RAD17 | Mlig455_048444 {REF} {Length: 2625} {TRANSSPLICED} {Pfam: Rad17 P-loop domain [PF03215.17, score=32.7]; AAA ATPase domain [PF13191.8, score=23.1]} {Human: ENSG00000152942, RAD17, RAD17 checkpoint clamp loader component, [RH, Score=83.2, Expect=4e-16]; ENSG00000276618, RAD17, RAD17 checkpoint clamp loader component, [RH, Score=83.2, Expect=3e-16]} {Mouse: ENSMUSG00000021635, Rad17, RAD17 checkpoint clamp loader component, [RH, Score=84.7, Expect=8e-17]} {Celegans: WBGene00001998, hpr-17, Homolog of S. Pombe Rad; Rad17-like protein, [RH, Score=62.4, Expect=4e-10]} {RNA1509_18035} {RNA1310_15935.1} {RNA815_10930} Mlig455_062732 {REF} {Length: 2722} {TRANSSPLICED} {Pfam: Rad17 P-loop domain [PF03215.17, score=32.7]; AAA ATPase domain [PF13191.8, score=23.1]} {Human: ENSG00000152942, RAD17, RAD17 checkpoint clamp loader component, [RH, Score=83.2, Expect=4e-16]; ENSG00000276618, RAD17, RAD17 checkpoint clamp loader component, [RH, Score=83.2, Expect=3e-16]} {Mouse: ENSMUSG00000021635, Rad17, RAD17 checkpoint clamp loader component, [RH, Score=84.7, Expect=8e-17]} {Celegans: WBGene00001998, hpr-17, Homolog of S. Pombe Rad; Rad17-like protein, [RH, Score=62.4, Expect=4e-10]} {RNA1509_18035} {RNA1310_15935.1, RNA1509_18035} {RNA1509_18035, RNA815_10930} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.016 | 4.147 | 0.99632 | 1.00000 | |
RegionR2 | 0.162 | 4.147 | 0.81593 | 1.00000 | |
RegionR3 | -0.166 | 4.147 | 0.76257 | 1.00000 | |
RegionR4 | 2.295 | 4.147 | 0.00016 | 0.00239 | |
RegionR5 | 0.701 | 4.147 | 0.12993 | 0.36581 | |
RegionR6 | -1.567 | 4.147 | 0.01031 | 0.17117 | |
RegionR7 | 0.417 | 4.147 | 0.50989 | 1.00000 | |
RegionR8 | -1.826 | 4.147 | 0.07555 | 0.52405 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 2.163 | 4.147 | 0.15957 | 0.90336 | |
RegenerationR2 | -0.485 | 4.147 | 0.41589 | 0.82450 | |
RegenerationR3 | -0.113 | 4.147 | 0.86375 | 1.00000 | |
RegenerationR4 | -0.855 | 4.147 | 0.17006 | 0.60667 | |
RegenerationR5 | 0.253 | 4.147 | 0.65502 | 0.93397 | |
RegenerationR6 | 1.408 | 4.147 | 0.04540 | 0.26601 | |
RegenerationBL | 1.058 | 4.147 | 0.18190 | 0.51089 | |
RegenerationTP | -0.184 | 4.147 | 0.84525 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_49273 | 592 | 12.33 | Mlig455_048444, Mlig455_062732 | Neo: Int S/G2/M Age: - Region-enriched R4: 2.295/0.00239 |
RAD17 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_048444 {REF} {Length: 2625} {TRANSSPLICED} {Pfam: Rad17 P-loop domain [PF03215.17, score=32.7]; AAA ATPase domain [PF13191.8, score=23.1]} {Human: ENSG00000152942, RAD17, RAD17 checkpoint clamp loader component, [RH, Score=83.2, Expect=4e-16]; ENSG00000276618, RAD17, RAD17 checkpoint clamp loader component, [RH, Score=83.2, Expect=3e-16]} {Mouse: ENSMUSG00000021635, Rad17, RAD17 checkpoint clamp loader component, [RH, Score=84.7, Expect=8e-17]} {Celegans: WBGene00001998, hpr-17, Homolog of S. Pombe Rad; Rad17-like protein, [RH, Score=62.4, Expect=4e-10]} {RNA1509_18035} {RNA1310_15935.1} {RNA815_10930} Mlig455_062732 {REF} {Length: 2722} {TRANSSPLICED} {Pfam: Rad17 P-loop domain [PF03215.17, score=32.7]; AAA ATPase domain [PF13191.8, score=23.1]} {Human: ENSG00000152942, RAD17, RAD17 checkpoint clamp loader component, [RH, Score=83.2, Expect=4e-16]; ENSG00000276618, RAD17, RAD17 checkpoint clamp loader component, [RH, Score=83.2, Expect=3e-16]} {Mouse: ENSMUSG00000021635, Rad17, RAD17 checkpoint clamp loader component, [RH, Score=84.7, Expect=8e-17]} {Celegans: WBGene00001998, hpr-17, Homolog of S. Pombe Rad; Rad17-like protein, [RH, Score=62.4, Expect=4e-10]} {RNA1509_18035} {RNA1310_15935.1, RNA1509_18035} {RNA1509_18035, RNA815_10930} |
2. | MligTC455_21296 | 1364 | 28.43 | Mlig455_038699 | Neo: Germline Age: - Region-specific R4: 4.483 Region-enriched R4: 2.386/0.00000 Regeneration-downregulated R4: -2.269 Regeneration-depleted R4: -2.269 |
3.149 | 0.712 | 0.784 | - | - | 0.952 | 0.701 | Mlig455_038699 {REF} {Length: 1131} {TRANSSPLICED} {RNA1509_19342, RNA1509_23653, RNA1509_37261, RNA1509_4702, RNA1509_5236} {RNA1310_31717, RNA1509_19342, RNA1509_23653, RNA1509_37261, RNA1509_4702, RNA1509_5236} {RNA1509_19342, RNA1509_23653, RNA1509_37261, RNA1509_4702, RNA1509_5236, RNA815_13757} | |
3. | MligTC455_13198 | 299 | 6.23 | Mlig455_037001 | Neo: Int S/G2/M Age: - Region-specific R4: 4.491 Region-enriched R4: 3.361/0.00000 |
ZFAND4 | 1.814 | - | 0.858 | - | - | - | 0.956 | Mlig455_037001 {REF} {Length: 2191} {TRANSSPLICED} {Pfam: AN1-like Zinc finger [PF01428.18, score=38.2]; Ubiquitin family [PF00240.25, score=30.1]} {Human: ENSG00000172671, ZFAND4, zinc finger AN1-type containing 4, [Score=89.0, Expect=4e-19]} {Mouse: ENSMUSG00000042213, Zfand4, zinc finger, AN1-type domain 4, [Score=87.0, Expect=1e-18]} {Dmel: FBgn0266410, CG45050, [Score=75.5, Expect=4e-16]} {Celegans: WBGene00009050, F22D6.2, [Score=74.7, Expect=6e-16]} {Smed: dd_Smed_v6_4992_0_1, dd_Smed_v6_4992_0_1, [Score=85.9, Expect=1e-18]} {RNA1509_11358, RNA1509_12571, RNA1509_40027, RNA1509_59148} {RNA1310_30429, RNA1509_11358, RNA1509_12571, RNA1509_40027, RNA1509_59148} {RNA1509_11358, RNA1509_12571, RNA1509_40027, RNA1509_59148, RNA815_16091} |
4. | MligTC455_20667 | 992 | 20.67 | Mlig455_031254, Mlig455_031299, Mlig455_031329 | Neo: Neoblast, stringent Age: logFC(26M/2M)=0.264 Region-enriched R5: 1.345/0.00244 |
XPC | 1.805 | - | - | - | 0.958 | - | 0.847 | Mlig455_031254 {REF} {Length: 234} {NoTransDecoderORF} {RNA1509_41875} {RNA1310_5347} Mlig455_031299 {REF} {Length: 5228} {Pfam: Rad4 beta-hairpin domain 3 [PF10405.11, score=85.1]; Rad4 beta-hairpin domain 2 [PF10404.11, score=58.3]; Rad4 beta-hairpin domain 1 [PF10403.11, score=54.1]; Rad4 transglutaminase-like domain [PF03835.17, score=50.1]} {Human: ENSG00000154767, XPC, XPC complex subunit, DNA damage recognition and repair factor, [RH, Score=292, Expect=5e-84]} {Mouse: ENSMUSG00000030094, Xpc, xeroderma pigmentosum, complementation group C, [RH, Score=302, Expect=6e-88]} {Dmel: FBgn0004698, Xpc, Xeroderma pigmentosum, complementation group C, [RH, Score=296, Expect=3e-84]} {Celegans: WBGene00022296, xpc-1, XPC (Xeroderma Pigmentosum group C) DNA repair gene homolog, [RH, Score=231, Expect=1e-62]} {Smed: dd_Smed_v6_5100_0_1, dd_Smed_v6_5100_0_1, [RH, Score=236, Expect=3e-67]} {RNA1509_22240, RNA1509_37174, RNA1509_43141} {RNA1310_2636, RNA1509_22240, RNA1509_37174, RNA1509_43141} {RNA1509_22240, RNA1509_37174, RNA1509_43141, RNA815_7190.1} Mlig455_031329 {REF} {Length: 3756} {TRANSSPLICED} {Pfam: Rad4 beta-hairpin domain 3 [PF10405.11, score=84.0]; Rad4 beta-hairpin domain 2 [PF10404.11, score=58.3]; Rad4 beta-hairpin domain 1 [PF10403.11, score=52.6]; Rad4 transglutaminase-like domain [PF03835.17, score=50.2]} {Human: ENSG00000154767, XPC, XPC complex subunit, DNA damage recognition and repair factor, [RH, Score=283, Expect=5e-81]} {Mouse: ENSMUSG00000030094, Xpc, xeroderma pigmentosum, complementation group C, [RH, Score=301, Expect=9e-88]} {Dmel: FBgn0004698, Xpc, Xeroderma pigmentosum, complementation group C, [RH, Score=296, Expect=2e-84]} {Celegans: WBGene00022296, xpc-1, XPC (Xeroderma Pigmentosum group C) DNA repair gene homolog, [RH, Score=229, Expect=3e-62]} {Smed: dd_Smed_v6_5100_0_1, dd_Smed_v6_5100_0_1, [RH, Score=237, Expect=2e-67]} {RNA1509_38140} {RNA1310_4273.2} {RNA815_7190.1} |
5. | MligTC455_20666 | 432 | 8.99 | Mlig455_031251 | Neo: Irradiation Age: - Region-enriched R5: 1.274/0.00795 |
XPC | 1.787 | - | - | - | 0.956 | - | 0.831 | Mlig455_031251 {REF} {Length: 7201} {TRANSSPLICED} {Pfam: Rad4 beta-hairpin domain 3 [PF10405.11, score=83.9]; Rad4 beta-hairpin domain 2 [PF10404.11, score=58.3]; Rad4 beta-hairpin domain 1 [PF10403.11, score=52.6]; Rad4 transglutaminase-like domain [PF03835.17, score=50.3]} {Human: ENSG00000154767, XPC, XPC complex subunit, DNA damage recognition and repair factor, [RH, Score=293, Expect=1e-84]} {Mouse: ENSMUSG00000030094, Xpc, xeroderma pigmentosum, complementation group C, [RH, Score=301, Expect=1e-87]} {Dmel: FBgn0004698, Xpc, Xeroderma pigmentosum, complementation group C, [RH, Score=295, Expect=1e-83]} {Celegans: WBGene00022296, xpc-1, XPC (Xeroderma Pigmentosum group C) DNA repair gene homolog, [RH, Score=228, Expect=1e-61]} {Smed: dd_Smed_v6_5100_0_1, dd_Smed_v6_5100_0_1, [RH, Score=237, Expect=2e-67]} {RNA1509_37174} {RNA1310_2636} {RNA815_7190.1} |
6. | MligTC455_25593 | 620 | 12.91 | Mlig455_010640 | Neo: - Age: Up-Down-Up |
1.66 | - | - | 0.707 | - | 0.953 | - | Mlig455_010640 {REF} {Length: 6295} {TRANSSPLICED} {RNA1509_21874, RNA1509_21918, RNA1509_4078} {RNA1310_3072, RNA1509_21874, RNA1509_21918} {RNA1509_21874, RNA1509_21918, RNA815_5186} | |
7. | MligTC455_33914 | 63 | 1.31 | Mlig455_069339 | Neo: - Age: - |
0.973 | - | - | - | - | 0.973 | - | Mlig455_069339 {REF} {Length: 2370} {Pfam: Spondin_N [PF06468.15, score=27.9]} {Dmel: FBgn0033710, CG17739, [Score=49.7, Expect=4e-06]} {RNA1310_29306} {RNA815_50316} | |
8. | MligTC455_47349 | 1450 | 30.22 | Mlig455_010530, Mlig455_061804 | Neo: Neoblast, stringent Age: - Region-enriched R5: 1.675/0.00004 |
DNMT3B | 0.969 | - | - | - | 0.969 | - | - | Mlig455_010530 {REF} {Length: 2248} {TRANSSPLICED} {Pfam: Cysteine rich ADD domain in DNMT3 [PF17980.3, score=29.7]} {Human: ENSG00000088305, DNMT3B, DNA methyltransferase 3 beta, [Score=89.0, Expect=1e-17]} {Mouse: ENSMUSG00000027478, Dnmt3b, DNA methyltransferase 3B, [Score=97.1, Expect=2e-20]; ENSMUSG00000082079, Dnmt3c, DNA methyltransferase 3C, [Score=94.7, Expect=1e-19]} {RNA1509_23149} {RNA1310_10697.1, RNA1509_23149} {RNA1509_23149, RNA815_14886} Mlig455_061804 {REF} {Length: 2249} {TRANSSPLICED} {Pfam: Cysteine rich ADD domain in DNMT3 [PF17980.3, score=29.7]} {Human: ENSG00000088305, DNMT3B, DNA methyltransferase 3 beta, [Score=89.4, Expect=9e-18]} {Mouse: ENSMUSG00000027478, Dnmt3b, DNA methyltransferase 3B, [Score=97.1, Expect=2e-20]; ENSMUSG00000082079, Dnmt3c, DNA methyltransferase 3C, [Score=94.7, Expect=9e-20]} {RNA1509_23149} {RNA1310_10697.1} {RNA815_14886} |
9. | MligTC455_14730 | 218 | 4.55 | Mlig455_031670 | Neo: - Age: - Region-enriched R4: 2.798/0.04773 |
GLIPR2 | 0.968 | - | - | - | - | 0.968 | - | Mlig455_031670 {REF} {Length: 1709} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=60.8]} {Human: ENSG00000122694, GLIPR2, GLI pathogenesis related 2, [Score=98.2, Expect=3e-25]} {Mouse: ENSMUSG00000028480, Glipr2, GLI pathogenesis-related 2, [Score=94.4, Expect=6e-24]} {Dmel: FBgn0051482, CG31482, [Score=92.8, Expect=5e-23]} {Celegans: WBGene00008604, F09B9.5, [Score=72.4, Expect=1e-15]} {Smed: dd_Smed_v6_762_0_1, dd_Smed_v6_762_0_1, [Score=116, Expect=9e-32]} {RNA1509_3027} {RNA1310_34590.1} {RNA815_14111.1} |
10. | MligTC455_45233 | 1587 | 33.07 | Mlig455_005544, Mlig455_036202 | Neo: Irradiation Age: - Region-enriched R5: 2.793/0.00000 |
0.957 | - | - | - | 0.957 | - | - | Mlig455_005544 {REF} {Length: 302} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_41201} {RNA1310_4034.2} {RNA815_13005.1} Mlig455_036202 {REF} {Length: 305} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_41201} {RNA1310_4034.2} {RNA815_13005.1} |
|
11. | MligTC455_42075 | 180 | 3.75 | Mlig455_051094 | Neo: - Age: - |
TRMT5 | 0.953 | - | - | - | - | 0.953 | - | Mlig455_051094 {REF} {Length: 2320} {TRANSSPLICED} {Pfam: Met-10+ like-protein [PF02475.18, score=174.2]} {Human: ENSG00000126814, TRMT5, tRNA methyltransferase 5, [RH, Score=247, Expect=1e-75]} {Mouse: ENSMUSG00000034442, Trmt5, TRM5 tRNA methyltransferase 5, [RH, Score=238, Expect=3e-72]} {Dmel: FBgn0052281, CG32281, [RH, Score=234, Expect=1e-71]} {Celegans: WBGene00194707, C53A5.17, tRNA (guanine(37)-N1)-methyltransferase, [RH, Score=207, Expect=5e-61]} {Smed: dd_Smed_v6_7597_0_1, dd_Smed_v6_7597_0_1, [RH, Score=248, Expect=4e-77]} {RNA1509_22770} {RNA1310_22058, RNA1509_22770} {RNA1509_22770, RNA815_8368} |
12. | MligTC455_51677 | 31 | 0.65 | Mlig455_024300 | Neo: - Age: - |
PRDM1 | 0.95 | - | - | - | - | 0.950 | - | Mlig455_024300 {REF} {Length: 3745} {Pfam: Zinc-finger double domain [PF13465.8, score=99.5]; Zinc finger, C2H2 type [PF00096.28, score=63.3]; C2H2-type zinc finger [PF13894.8, score=34.7]; Zinc-finger of C2H2 type [PF12874.9, score=20.3]} {Human: ENSG00000057657, PRDM1, PR/SET domain 1, [RH, Score=263, Expect=6e-78]} {Mouse: ENSMUSG00000038151, Prdm1, PR domain containing 1, with ZNF domain, [RH, Score=265, Expect=1e-78]} {Dmel: FBgn0035625, Blimp-1, [RH, Score=282, Expect=4e-83]} {Celegans: WBGene00003847, blmp-1, B lymphocyte-induced maturation protein 1 homolog, [RH, Score=244, Expect=4e-71]} {Smed: dd_Smed_v6_19859_0_1, dd_Smed_v6_19859_0_1, [RH, Score=259, Expect=1e-80]} {RNA1509_17032} {RNA1310_20903, RNA1509_17032} {RNA1509_17032, RNA815_21750} |