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Results for MligTC455_49922

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_49922 36 0.76 Mlig455_049338

Neo: -

Age: Down-Down-Up

Region-enriched R2: 7.622/0.00496

Mlig455_049338 {REF} {Length: 971} {RNA1310_37449} {RNA815_3585}

Cumulative graph for MligTC455_49922

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -3.32 1.193 0.99956 1.00000
RegionR2 7.622 1.193 0.00013 0.00496
RegionR3 -0.429 1.193 0.99977 1.00000
RegionR4 -1.891 1.193 0.82332 1.00000
RegionR5 -0.393 1.193 0.65505 1.00000
RegionR6 -1.115 1.193 0.99972 1.00000
RegionR7 -0.342 1.193 0.99978 1.00000
RegionR8 -0.131 1.193 0.99970 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.91 1.193 0.99998 1.00000
RegenerationR2 -2.714 1.193 0.00613 0.12521
RegenerationR3 1.921 1.193 0.26492 0.69979
RegenerationR4 2.228 1.193 0.19605 0.64114
RegenerationR5 1.505 1.193 0.33481 0.75452
RegenerationR6 1.249 1.193 0.43518 0.76096
RegenerationBL 3.405 1.193 0.16737 0.49020
RegenerationTP 1.218 1.193 0.59265 0.95619


Genes with expression patterns similar to MligTC455_49922

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_49922 36 0.76 Mlig455_049338

Neo: -

Age: Down-Down-Up

Region-enriched R2: 7.622/0.00496

4 - 1.000 1.000 - 1.000 1.000 Mlig455_049338 {REF} {Length: 971} {RNA1310_37449} {RNA815_3585}
2. MligTC455_44725 67 1.4 Mlig455_024194

Neo: -

Age: -

2.856 - 0.958 0.966 - 0.932 - Mlig455_024194 {REF} {Length: 956} {RNA1310_84543} {RNA815_47586}
3. MligTC455_53658 41 0.86 Mlig455_070698

Neo: -

Age: Up-Down-Down

Region-enriched R2: 9.084/0.01491

2.83 - 0.993 0.958 - 0.879 - Mlig455_070698 {REF} {Length: 1026} {RNA1509_40972} {RNA1310_35649.1} {RNA815_17004}
4. MligTC455_51807 28 0.59 Mlig455_046394

Neo: -

Age: -

GPSM2 2.829 - 0.946 0.974 - 0.909 - Mlig455_046394 {REF} {Length: 3388} {Pfam: Tetratricopeptide repeat [PF13424.8, score=114.4]; Tetratricopeptide repeat [PF13176.8, score=96.0]; Tetratricopeptide repeat [PF00515.30, score=94.3]; GoLoco motif [PF02188.19, score=85.6]; Tetratricopeptide repeat [PF07719.19, score=55.0]; Tetratricopeptide repeat [PF13181.8, score=42.2]; Tetratricopeptide repeat [PF13374.8, score=32.8]; Rapsyn N-terminal myristoylation and linker region [PF10579.11, score=20.1]} {Human: ENSG00000121957, GPSM2, G protein signaling modulator 2, [RH, Score=542, Expect=0.0]} {Mouse: ENSMUSG00000027883, Gpsm2, G-protein signalling modulator 2 (AGS3-like, C. elegans), [RH, Score=532, Expect=1e-180]; ENSMUSG00000026930, Gpsm1, G-protein signalling modulator 1 (AGS3-like, C. elegans), [RH, Score=511, Expect=1e-172]} {Dmel: FBgn0040080, pins, partner of inscuteable, [RH, Score=530, Expect=2e-180]} {Celegans: WBGene00000092, ags-3, Activator of G protein Signalling, [RH, Score=266, Expect=7e-80]} {Smed: dd_Smed_v6_6548_1_1, dd_Smed_v6_6548_1_1, [RH, Score=477, Expect=1e-159]} {RNA1310_18538} {RNA815_41322}
5. MligTC455_43137 118 2.46 Mlig455_043159

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.878

Region-enriched R2: 5.988/0.00166
Region-enriched R4: 3.958/0.04103

2.828 - 0.990 0.879 - 0.959 - Mlig455_043159 {REF} {Length: 1651} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=25.7]} {RNA1509_48871} {RNA1310_23692, RNA1509_48871} {RNA1509_48871, RNA815_11317}
6. MligTC455_17479 32 0.66 Mlig455_032081, Mlig455_070278

Neo: -

Age: logFC(26M/2M)=-0.516

CHRNA3 2.812 - 0.989 0.858 - 0.965 -

Mlig455_032081 {REF} {Length: 2787} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=230.7]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=221.4]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=368, Expect=1e-121]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=366, Expect=5e-121]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=378, Expect=6e-126]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=361, Expect=3e-119]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=461, Expect=3e-158]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=381, Expect=3e-127]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=614, Expect=0.0]} {RNA1509_28642} {RNA1310_34709} {RNA815_44960}

Mlig455_070278 {REF} {Length: 2270} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=232.1]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=221.2]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=369, Expect=7e-122]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=366, Expect=4e-121]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=378, Expect=9e-126]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=362, Expect=1e-119]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=461, Expect=3e-158]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=382, Expect=2e-127]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=616, Expect=0.0]} {RNA1509_16247} {RNA1310_34709} {RNA815_44960}
7. MligTC455_27678 355 7.4 Mlig455_070610

Neo: -

Age: -

Region-specific R2: 4.724

Region-enriched R2: 3.766/0.00062

2.81 - 0.912 0.978 - 0.920 - Mlig455_070610 {REF} {Length: 725} {RNA1509_17468, RNA1509_34237} {RNA1310_59474, RNA1509_17468, RNA1509_34237} {RNA1509_17468, RNA1509_34237, RNA815_28024}
8. MligTC455_30634 114 2.38 Mlig455_025888

Neo: -

Age: Up-Down-Up

Region-enriched R2: 6.750/0.00140

2.806 - 0.982 0.954 - 0.870 - Mlig455_025888 {REF} {Length: 5266} {Pfam: Integrase core domain [PF00665.28, score=50.8]; DDE superfamily endonuclease [PF13358.8, score=22.0]} {Smed: dd_Smed_v6_1574_6_72, dd_Smed_v6_1574_6_72, [Score=149, Expect=3e-41]} {RNA1509_47056} {RNA1310_5710.1} {RNA815_6291.1}
9. MligTC455_17363 62 1.28 Mlig455_003936

Neo: -

Age: -

2.802 - 0.981 0.902 - 0.919 - Mlig455_003936 {REF} {Length: 1252} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=45.9]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=26.4]} {RNA1310_47889} {RNA815_24646}
10. MligTC455_13902 400 8.32 Mlig455_011022, Mlig455_011835, Mlig455_013117

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.562

Region-specific R2: 6.064

Region-enriched R2: 5.080/0.00072

2.796 - 0.960 0.939 - 0.897 -

Mlig455_011022 {REF} {Length: 631} {RNA1509_28527} {RNA1310_38436.1} {RNA815_28856}

Mlig455_011835 {REF} {Length: 2387} {RNA1509_28527} {RNA1310_38436.1} {RNA815_28856}

Mlig455_013117 {REF} {Length: 1663} {NoTransDecoderORF} {RNA1310_40518} {RNA815_20411.2}
11. MligTC455_52527 28 0.58 Mlig455_025836

Neo: -

Age: -

FLVCR2 2.786 - 0.992 0.964 - 0.830 - Mlig455_025836 {REF} {Length: 2177} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=81.4]; Sugar (and other) transporter [PF00083.26, score=18.7]} {Human: ENSG00000119686, FLVCR2, feline leukemia virus subgroup C cellular receptor family member 2, [RH, Score=364, Expect=5e-119]} {Mouse: ENSMUSG00000034258, Flvcr2, feline leukemia virus subgroup C cellular receptor 2, [RH, Score=367, Expect=3e-120]} {Dmel: FBgn0033196, CG1358, [RH, Score=350, Expect=1e-114]} {Celegans: WBGene00015632, C09D4.1, Uncharacterized MFS-type transporter C09D4.1, [RH, Score=358, Expect=1e-116]} {Smed: dd_Smed_v6_7578_0_1, dd_Smed_v6_7578_0_1, [Score=335, Expect=3e-109]} {RNA1509_31725} {RNA1310_8852.1} {RNA815_14234}
12. MligTC455_10229 24 0.49 Mlig455_023615

Neo: -

Age: -

2.772 - 0.997 0.858 - 0.917 - Mlig455_023615 {REF} {Length: 1635} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=22.2]} {RNA1310_22533.3} {RNA815_23050}
13. MligTC455_18139 70 1.45 Mlig455_010809

Neo: -

Age: logFC(26M/2M)=-0.809

Region-enriched R2: 6.868/0.00081

TRPC5 2.772 - 0.991 0.911 - 0.870 - Mlig455_010809 {REF} {Length: 4442} {Pfam: Ion transport protein [PF00520.33, score=98.6]; Transient receptor ion channel II [PF08344.13, score=94.3]; Polycystin cation channel [PF08016.14, score=49.0]; Ankyrin repeats (many copies) [PF13637.8, score=37.1]; Ankyrin repeats (3 copies) [PF12796.9, score=33.2]; Ankyrin repeat [PF13606.8, score=25.4]; Ankyrin repeats (many copies) [PF13857.8, score=24.1]; Ankyrin repeat [PF00023.32, score=23.2]} {Human: ENSG00000072315, TRPC5, transient receptor potential cation channel subfamily C member 5, [RH, Score=743, Expect=0.0]; ENSG00000133107, TRPC4, transient receptor potential cation channel subfamily C member 4, [RH, Score=740, Expect=0.0]} {Mouse: ENSMUSG00000041710, Trpc5, transient receptor potential cation channel, subfamily C, member 5, [RH, Score=744, Expect=0.0]; ENSMUSG00000027748, Trpc4, transient receptor potential cation channel, subfamily C, member 4, [RH, Score=740, Expect=0.0]} {Dmel: FBgn0032593, Trpgamma, Transient receptor potential cation channel gamma, [RH, Score=848, Expect=0.0]} {Celegans: WBGene00006615, trp-2, TRP (Transient receptor potential) channel family; TRP homlogous cation channel protein, [RH, Score=694, Expect=0.0]} {Smed: dd_Smed_v6_20495_0_1, dd_Smed_v6_20495_0_1, [RH, Score=1017, Expect=0.0]} {RNA1509_34138} {RNA1310_12839, RNA1509_34138} {RNA1509_34138, RNA815_17637}
14. MligTC455_10227 76 1.59 Mlig455_023507, Mlig455_023516, Mlig455_023551

Neo: -

Age: -

2.771 - 0.996 0.858 - 0.917 -

Mlig455_023507 {REF} {Length: 1545} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=21.8]} {RNA1310_22533.3} {RNA815_23050}

Mlig455_023516 {REF} {Length: 1641} {RNA1310_22533.3} {RNA815_23050}

Mlig455_023551 {REF} {Length: 1638} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=22.2]} {RNA1310_22533.3} {RNA815_26724.1}
15. MligTC455_37701 47 0.98 Mlig455_029831

Neo: -

Age: -

Region-enriched R2: 8.298/0.02665

2.766 - 0.967 0.946 - 0.853 - Mlig455_029831 {REF} {Length: 724} {RNA1310_73844}
16. MligTC455_08408 41 0.86 Mlig455_043171

Neo: -

Age: Up-Down-Down

2.763 - 0.997 0.862 - 0.904 - Mlig455_043171 {REF} {Length: 1568} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=19.4]} {RNA1310_47844} {RNA815_49360}
17. MligTC455_09874 31 0.65 Mlig455_045071

Neo: -

Age: -

DOC2A 2.746 - 0.997 0.841 - 0.908 - Mlig455_045071 {REF} {Length: 1760} {Pfam: C2 domain [PF00168.32, score=55.9]} {Human: ENSG00000149927, DOC2A, double C2 domain alpha, [Score=55.8, Expect=7e-08]} {Mouse: ENSMUSG00000052301, Doc2a, double C2, alpha, [Score=55.5, Expect=7e-08]} {Celegans: WBGene00004923, snt-3, SyNapTotagmin, [Score=70.5, Expect=2e-13]} {Smed: dd_Smed_v6_16731_0_1, dd_Smed_v6_16731_0_1, [Score=112, Expect=7e-27]} {RNA1310_36283} {RNA815_40844}
18. MligTC455_10226 119 2.48 Mlig455_023508, Mlig455_023518, Mlig455_023617

Neo: -

Age: -

2.746 - 0.995 0.833 - 0.918 -

Mlig455_023508 {REF} {Length: 1311} {RNA1310_22533.2} {RNA815_23050}

Mlig455_023518 {REF} {Length: 1413} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=21.5]} {RNA1310_22533.2} {RNA815_23050}

Mlig455_023617 {REF} {Length: 1414} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=19.6]} {RNA1310_22533.2} {RNA815_23050}
19. MligTC455_36566 40 0.83 Mlig455_053263

Neo: -

Age: -

Region-enriched R2: 4.823/0.01830

2.737 - 0.978 0.843 - 0.916 - Mlig455_053263 {REF} {Length: 1228} {TRANSSPLICED} {RNA1310_99871}
20. MligTC455_35000 20 0.42 Mlig455_050562

Neo: -

Age: -

KCNC1 2.733 - 0.975 0.858 - 0.900 - Mlig455_050562 {REF} {Length: 3042} {Pfam: Ion transport protein [PF00520.33, score=116.8]; BTB/POZ domain [PF02214.24, score=75.0]; Ion channel [PF07885.18, score=42.0]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=211, Expect=2e-60]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=209, Expect=1e-58]; ENSG00000182674, KCNB2, potassium voltage-gated channel subfamily B member 2, [Score=206, Expect=3e-56]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=204, Expect=3e-57]; ENSG00000158445, KCNB1, potassium voltage-gated channel subfamily B member 1, [Score=204, Expect=1e-55]; ENSG00000131398, KCNC3, potassium voltage-gated channel subfamily C member 3, [Score=203, Expect=7e-56]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=212, Expect=3e-60]; ENSMUSG00000050556, Kcnb1, potassium voltage gated channel, Shab-related subfamily, member 1, [Score=209, Expect=2e-57]; ENSMUSG00000092083, Kcnb2, potassium voltage gated channel, Shab-related subfamily, member 2, [Score=206, Expect=2e-56]; ENSMUSG00000027895, Kcnc4, potassium voltage gated channel, Shaw-related subfamily, member 4, [Score=204, Expect=4e-57]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=203, Expect=1e-56]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [Score=203, Expect=4e-56]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=223, Expect=2e-65]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=224, Expect=8e-65]} {Smed: dd_Smed_v6_20858_0_1, dd_Smed_v6_20858_0_1, [RH, Score=567, Expect=0.0]} {RNA1509_22940} {RNA1310_28483} {RNA815_31040}
21. MligTC455_51760 18 0.38 Mlig455_051796

Neo: -

Age: -

CNBD2 2.718 - - 0.958 - 0.988 0.772 Mlig455_051796 {REF} {Length: 2614} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=74.7]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [Score=67.4, Expect=2e-11]; ENSG00000185532, PRKG1, protein kinase cGMP-dependent 1, [Score=64.3, Expect=4e-10]} {Mouse: ENSMUSG00000052920, Prkg1, protein kinase, cGMP-dependent, type I, [Score=64.7, Expect=2e-10]; ENSMUSG00000038085, Cnbd2, cyclic nucleotide binding domain containing 2, [Score=63.9, Expect=2e-10]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [Score=57.4, Expect=1e-08]} {Celegans: WBGene00015650, pkg-2, Protein Kinase, cGMP-dependent, [Score=61.2, Expect=1e-09]} {Smed: dd_Smed_v6_17565_0_1, dd_Smed_v6_17565_0_1, [Score=174, Expect=1e-46]} {RNA1310_33768} {RNA815_47620}
22. MligTC455_47197 155 3.24 Mlig455_049096, Mlig455_049118

Neo: -

Age: -

2.709 - 0.972 0.907 - 0.830 -

Mlig455_049096 {REF} {Length: 3209} {Smed: dd_Smed_v6_14861_0_1, dd_Smed_v6_14861_0_1, [Score=151, Expect=1e-37]} {RNA1509_52343} {RNA1310_44918.1} {RNA815_41725}

Mlig455_049118 {REF} {Length: 3116} {Smed: dd_Smed_v6_14861_0_1, dd_Smed_v6_14861_0_1, [Score=160, Expect=1e-40]} {RNA1509_52343} {RNA1310_44918.1} {RNA815_41725}
23. MligTC455_41443 382 7.96 Mlig455_034791, Mlig455_034803

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.360

Region-enriched R2: 5.869/0.00205

2.7 - 0.993 0.836 - 0.871 -

Mlig455_034791 {REF} {Length: 996} {RNA1310_39610.1} {RNA815_26421}

Mlig455_034803 {REF} {Length: 1084} {RNA1310_39610.1} {RNA815_26421}
24. MligTC455_23220 56 1.18 Mlig455_060190

Neo: -

Age: -

ACKR3 2.688 - 0.963 0.877 - 0.848 - Mlig455_060190 {REF} {Length: 2108} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=106.0]} {Human: ENSG00000144476, ACKR3, atypical chemokine receptor 3, [RH, Score=99.0, Expect=1e-22]} {Mouse: ENSMUSG00000026180, Cxcr2, chemokine (C-X-C motif) receptor 2, [Score=112, Expect=1e-27]} {Dmel: FBgn0266429, AstA-R1, Allatostatin A receptor 1, [Score=102, Expect=4e-24]} {Celegans: WBGene00021439, ckr-2, CholecystoKinin Receptor homolog; Cholecystokinin receptor 2 splice isoform b, [Score=68.2, Expect=2e-12]} {Smed: dd_Smed_v6_10325_0_1, dd_Smed_v6_10325_0_1, [Score=81.6, Expect=5e-17]} {RNA1310_66504} {RNA815_39432}
25. MligTC455_47110 34 0.7 Mlig455_025028

Neo: -

Age: -

2.678 - 0.956 0.803 - 0.919 - Mlig455_025028 {REF} {Length: 521} {RNA1509_55651} {RNA1310_59019} {RNA815_42240}
26. MligTC455_10228 50 1.05 Mlig455_023553

Neo: -

Age: -

2.669 - 0.995 0.756 - 0.918 - Mlig455_023553 {REF} {Length: 1195} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=20.0]} {RNA1310_22533.1} {RNA815_23050}
27. MligTC455_13903 648 13.5 Mlig455_013116

Neo: -

Age: logFC(26M/2M)=-1.026

Region-specific R2: 6.980

Region-enriched R2: 7.338/0.00000

2.666 - 0.983 0.785 - 0.898 - Mlig455_013116 {REF} {Length: 914} {RNA1509_28527} {RNA1310_38436.2, RNA1509_28527} {RNA1509_28527, RNA815_28856}
28. MligTC455_17565 85 1.77 Mlig455_054318

Neo: -

Age: -

Region-enriched R2: 6.111/0.00708

2.635 - 0.815 0.963 - 0.857 - Mlig455_054318 {REF} {Length: 550} {RNA1310_73705} {RNA815_38857}
29. MligTC455_17394 41 0.85 Mlig455_013077

Neo: -

Age: -

2.628 - 0.994 0.731 - 0.903 - Mlig455_013077 {REF} {Length: 1066} {RNA1310_66954} {RNA815_27868}
30. MligTC455_35103 102 2.12 Mlig455_023928

Neo: -

Age: logFC(26M/2M)=-1.570

Region-enriched R2: 8.161/0.00000

OPN4 2.616 - 0.978 0.894 - 0.744 - Mlig455_023928 {REF} {Length: 2781} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=179.7]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=34.7]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=28.9]; Olfactory receptor [PF13853.8, score=24.6]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=19.1]} {Human: ENSG00000122375, OPN4, opsin 4, [RH, Score=218, Expect=2e-65]} {Mouse: ENSMUSG00000021799, Opn4, opsin 4 (melanopsin), [RH, Score=225, Expect=1e-68]} {Dmel: FBgn0014019, Rh5, Rhodopsin 5, [RH, Score=222, Expect=2e-68]} {Celegans: WBGene00009619, npr-6, NeuroPeptide Receptor family, [Score=91.3, Expect=4e-20]} {Smed: dd_Smed_v6_15036_0_1, dd_Smed_v6_15036_0_1, [RH, Score=520, Expect=0.0]} {RNA1509_41123} {RNA1310_10673, RNA1509_41123} {RNA1509_41123, RNA815_4962}
31. MligTC455_33772 104 2.17 Mlig455_016493

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.862/0.00025
Region-enriched R7: 4.134/0.00118

2.61 - 0.802 0.950 - 0.858 - Mlig455_016493 {REF} {Length: 883} {RNA1310_43848} {RNA815_55624}
32. MligTC455_13049 53 1.11 Mlig455_029230, Mlig455_029252, Mlig455_035639, Mlig455_035735

Neo: -

Age: Down-Up-Down

Region-enriched R2: 6.077/0.00215

HTR2A 2.605 - 0.997 0.858 - 0.750 -

Mlig455_029230 {REF} {Length: 2756} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=149.9]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=46.0]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=25.6]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=24.1]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=19.2]} {Human: ENSG00000102468, HTR2A, 5-hydroxytryptamine receptor 2A, [Score=142, Expect=3e-37]} {Mouse: ENSMUSG00000034997, Htr2a, 5-hydroxytryptamine (serotonin) receptor 2A, [Score=141, Expect=5e-37]; ENSMUSG00000041380, Htr2c, 5-hydroxytryptamine (serotonin) receptor 2C, [Score=138, Expect=8e-36]} {Dmel: FBgn0261929, 5-HT2B, 5-hydroxytryptamine (serotonin) receptor 2B, [Score=131, Expect=1e-32]} {Celegans: WBGene00004776, ser-1, SERotonin/octopamine receptor family; Serotonin receptor, [Score=120, Expect=2e-29]} {Smed: dd_Smed_v6_24518_0_1, dd_Smed_v6_24518_0_1, [RH, Score=281, Expect=8e-90]} {RNA1310_91864}

Mlig455_029252 {REF} {Length: 2844} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=188.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=43.8]; Spt20 family [PF12090.10, score=21.4]} {Human: ENSG00000102468, HTR2A, 5-hydroxytryptamine receptor 2A, [Score=144, Expect=2e-36]} {Mouse: ENSMUSG00000034997, Htr2a, 5-hydroxytryptamine (serotonin) receptor 2A, [Score=142, Expect=4e-36]; ENSMUSG00000041380, Htr2c, 5-hydroxytryptamine (serotonin) receptor 2C, [Score=140, Expect=1e-35]} {Dmel: FBgn0004514, Oct-TyrR, Octopamine-Tyramine receptor, [Score=136, Expect=2e-33]} {Celegans: WBGene00006475, tyra-3, TYRAmine receptor, [Score=157, Expect=2e-41]} {Smed: dd_Smed_v6_24518_0_1, dd_Smed_v6_24518_0_1, [RH, Score=336, Expect=4e-108]} {RNA1310_91864}

Mlig455_035639 {REF} {Length: 2811} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=182.5]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=43.7]; Spt20 family [PF12090.10, score=24.8]} {Human: ENSG00000102468, HTR2A, 5-hydroxytryptamine receptor 2A, [Score=144, Expect=2e-36]} {Mouse: ENSMUSG00000034997, Htr2a, 5-hydroxytryptamine (serotonin) receptor 2A, [Score=143, Expect=3e-36]; ENSMUSG00000041380, Htr2c, 5-hydroxytryptamine (serotonin) receptor 2C, [Score=141, Expect=1e-35]} {Dmel: FBgn0261929, 5-HT2B, 5-hydroxytryptamine (serotonin) receptor 2B, [Score=133, Expect=6e-32]} {Celegans: WBGene00006475, tyra-3, TYRAmine receptor, [Score=156, Expect=5e-41]} {Smed: dd_Smed_v6_24518_0_1, dd_Smed_v6_24518_0_1, [RH, Score=284, Expect=3e-88]} {RNA1310_91864}

Mlig455_035735 {REF} {Length: 1469} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=140.9]; Spt20 family [PF12090.10, score=23.0]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=18.8]} {Human: ENSG00000102468, HTR2A, 5-hydroxytryptamine receptor 2A, [Score=97.1, Expect=3e-21]; ENSG00000147246, HTR2C, 5-hydroxytryptamine receptor 2C, [Score=95.1, Expect=2e-20]} {Mouse: ENSMUSG00000034997, Htr2a, 5-hydroxytryptamine (serotonin) receptor 2A, [Score=95.5, Expect=1e-20]; ENSMUSG00000041380, Htr2c, 5-hydroxytryptamine (serotonin) receptor 2C, [Score=93.2, Expect=6e-20]} {Dmel: FBgn0261929, 5-HT2B, 5-hydroxytryptamine (serotonin) receptor 2B, [Score=89.0, Expect=2e-18]} {Celegans: WBGene00006475, tyra-3, TYRAmine receptor, [Score=115, Expect=1e-27]} {Smed: dd_Smed_v6_31134_0_1, dd_Smed_v6_31134_0_1, [Score=249, Expect=4e-77]} {RNA1310_91864}
33. MligTC455_12269 42 0.88 Mlig455_062448

Neo: -

Age: -

Region-enriched R2: 6.351/0.02912

2.598 - 0.976 0.764 - 0.858 - Mlig455_062448 {REF} {Length: 941} {RNA1310_43338} {RNA815_24238}
34. MligTC455_18140 171 3.56 Mlig455_033232

Neo: -

Age: Up-Down-Down

Region-specific R2: 6.925

Region-enriched R2: 6.274/0.02921

TRPC5 2.598 - 0.987 0.899 - 0.712 - Mlig455_033232 {REF} {Length: 4524} {Pfam: Ion transport protein [PF00520.33, score=98.6]; Transient receptor ion channel II [PF08344.13, score=94.3]; Polycystin cation channel [PF08016.14, score=49.0]; Ankyrin repeats (many copies) [PF13637.8, score=37.2]; Ankyrin repeats (3 copies) [PF12796.9, score=33.2]; Ankyrin repeat [PF13606.8, score=25.5]; Ankyrin repeats (many copies) [PF13857.8, score=24.1]; Ankyrin repeat [PF00023.32, score=23.2]} {Human: ENSG00000072315, TRPC5, transient receptor potential cation channel subfamily C member 5, [RH, Score=743, Expect=0.0]; ENSG00000133107, TRPC4, transient receptor potential cation channel subfamily C member 4, [RH, Score=742, Expect=0.0]} {Mouse: ENSMUSG00000041710, Trpc5, transient receptor potential cation channel, subfamily C, member 5, [RH, Score=745, Expect=0.0]; ENSMUSG00000027748, Trpc4, transient receptor potential cation channel, subfamily C, member 4, [RH, Score=742, Expect=0.0]} {Dmel: FBgn0032593, Trpgamma, Transient receptor potential cation channel gamma, [RH, Score=848, Expect=0.0]} {Celegans: WBGene00006615, trp-2, TRP (Transient receptor potential) channel family; TRP homlogous cation channel protein, [RH, Score=696, Expect=0.0]} {Smed: dd_Smed_v6_20495_0_1, dd_Smed_v6_20495_0_1, [RH, Score=1016, Expect=0.0]} {RNA1509_34138} {RNA1310_12839} {RNA815_17637}
35. MligTC455_19249 90 1.86 Mlig455_054092

Neo: -

Age: Down-Up-Up

Region-enriched R2: 7.298/0.00139

2.59 - 0.758 0.961 - 0.871 - Mlig455_054092 {REF} {Length: 667} {TRANSSPLICED} {RNA1509_57448} {RNA1310_51394, RNA1509_57448} {RNA1509_57448, RNA815_26076}
36. MligTC455_49285 164 3.41 Mlig455_004486, Mlig455_037380

Neo: -

Age: -

Region-specific R2: 6.095

Region-enriched R2: 5.942/0.00244

LEF1 2.587 - 0.961 0.734 - 0.892 -

Mlig455_004486 {REF} {Length: 3612} {Pfam: HMG (high mobility group) box [PF00505.21, score=30.1]} {Human: ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [Score=105, Expect=2e-24]; ENSG00000081059, TCF7, transcription factor 7, [Score=103, Expect=3e-25]; ENSG00000152284, TCF7L1, transcription factor 7 like 1, [Score=100, Expect=2e-22]} {Mouse: ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [Score=105, Expect=6e-25]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [Score=101, Expect=8e-24]; ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [Score=100, Expect=1e-22]} {Dmel: FBgn0085432, pan, pangolin, [Score=103, Expect=1e-23]} {Celegans: WBGene00004077, pop-1, [Score=82.0, Expect=8e-17]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [Score=114, Expect=3e-29]} {RNA1509_13914} {RNA1310_16097} {RNA815_47141}

Mlig455_037380 {REF} {Length: 3365} {Pfam: HMG (high mobility group) box [PF00505.21, score=78.7]; HMG-box domain [PF09011.12, score=32.5]} {Human: ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=156, Expect=1e-43]; ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=154, Expect=7e-41]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=154, Expect=3e-44]; ENSG00000148737, TCF7L2, transcription factor 7 like 2, [RH, Score=150, Expect=6e-44]} {Mouse: ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=157, Expect=9e-44]; ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=156, Expect=1e-41]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=153, Expect=1e-42]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=155, Expect=1e-40]} {Celegans: WBGene00004077, pop-1, [Score=104, Expect=4e-24]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=165, Expect=2e-48]} {RNA1509_13914} {RNA1310_16097} {RNA815_47141}
37. MligTC455_20757 286 5.96 Mlig455_005125, Mlig455_005185

Neo: -

Age: -

2.573 - 0.952 0.798 - 0.823 -

Mlig455_005125 {REF} {Length: 1290} {RNA1310_29676.2} {RNA815_31533}

Mlig455_005185 {REF} {Length: 1357} {RNA1310_29676.1} {RNA815_31533}
38. MligTC455_11109 30 0.62 Mlig455_043718, Mlig455_043804

Neo: -

Age: Up-Down-Down

2.571 - 0.974 0.743 - 0.854 -

Mlig455_043718 {REF} {Length: 1591} {RNA1310_49834.1} {RNA815_39415}

Mlig455_043804 {REF} {Length: 1594} {RNA1310_49834.2} {RNA815_39415}
39. MligTC455_42136 34 0.7 Mlig455_024685, Mlig455_024710, Mlig455_044068

Neo: -

Age: -

2.565 - 0.744 0.858 - 0.963 -

Mlig455_024685 {REF} {Length: 3505} {Pfam: Peptidase family M13 [PF05649.15, score=22.4]} {RNA1310_55586} {RNA815_38189}

Mlig455_024710 {REF} {Length: 3484} {RNA1310_55586} {RNA815_38189}

Mlig455_044068 {REF} {Length: 2578} {Pfam: Peptidase family M13 [PF05649.15, score=26.4]}
40. MligTC455_08098 15 0.31 Mlig455_029099

Neo: -

Age: -

Region-enriched R2: 8.013/0.00338

2.535 - 0.997 0.796 - 0.742 - Mlig455_029099 {REF} {Length: 1334} {RNA1310_58776} {RNA815_46110}
41. MligTC455_19758 53 1.1 Mlig455_002464

Neo: -

Age: -

Region-enriched R2: 6.578/0.02863

2.534 - 0.833 0.990 - 0.711 - Mlig455_002464 {REF} {Length: 2549} {RNA1310_38437} {RNA815_40458}
42. MligTC455_37412 95 1.98 Mlig455_036605, Mlig455_036645

Neo: -

Age: -

ADRA2A 2.508 - 0.997 - - 0.777 0.734

Mlig455_036605 {REF} {Length: 3015} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=97.8]} {Human: ENSG00000150594, ADRA2A, adrenoceptor alpha 2A, [Score=55.5, Expect=2e-07]; ENSG00000082556, OPRK1, opioid receptor kappa 1, [Score=55.1, Expect=2e-07]} {Mouse: ENSMUSG00000033717, Adra2a, adrenergic receptor, alpha 2a, [Score=56.6, Expect=5e-08]} {Dmel: FBgn0053517, Dop2R, Dopamine 2-like receptor, [Score=64.7, Expect=1e-10]} {Celegans: WBGene00016037, dop-6, DOPamine receptor, [Score=52.4, Expect=7e-07]} {Smed: dd_Smed_v6_23525_0_1, dd_Smed_v6_23525_0_1, [RH, Score=136, Expect=5e-35]} {RNA1310_57451} {RNA815_47300}

Mlig455_036645 {REF} {Length: 3203} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=97.0]} {Human: ENSG00000150594, ADRA2A, adrenoceptor alpha 2A, [Score=55.5, Expect=2e-07]; ENSG00000082556, OPRK1, opioid receptor kappa 1, [Score=55.1, Expect=1e-07]} {Mouse: ENSMUSG00000033717, Adra2a, adrenergic receptor, alpha 2a, [Score=56.6, Expect=4e-08]} {Dmel: FBgn0053517, Dop2R, Dopamine 2-like receptor, [Score=63.2, Expect=4e-10]} {Celegans: WBGene00016037, dop-6, DOPamine receptor, [Score=52.4, Expect=6e-07]} {Smed: dd_Smed_v6_23525_0_1, dd_Smed_v6_23525_0_1, [RH, Score=136, Expect=6e-35]} {RNA1310_57451} {RNA815_47300}
43. MligTC455_17266 62 1.3 Mlig455_043650

Neo: -

Age: -

1.933 - 0.994 0.939 - - - Mlig455_043650 {REF} {Length: 2826} {RNA1310_48878} {RNA815_25527}
44. MligTC455_00245 15 0.32 Mlig455_040042

Neo: -

Age: -

GPR17 1.918 - - 0.972 - 0.946 - Mlig455_040042 {REF} {Length: 1332} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=36.0]} {Human: ENSG00000144230, GPR17, G protein-coupled receptor 17, [Score=48.9, Expect=6e-06]} {Smed: dd_Smed_v6_61185_0_1, dd_Smed_v6_61185_0_1, [Score=70.9, Expect=1e-14]} {RNA1310_142905}
45. MligTC455_44661 48 1 Mlig455_038182

Neo: -

Age: logFC(26M/2M)=-0.564

ANO7 1.913 - 0.959 0.954 - - - Mlig455_038182 {REF} {Length: 3290} {Pfam: Calcium-activated chloride channel [PF04547.14, score=599.2]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=223.8]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=582, Expect=0.0]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=572, Expect=0.0]} {Dmel: FBgn0038721, subdued, [Score=422, Expect=3e-132]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=163, Expect=4e-41]} {Smed: dd_Smed_v6_19189_0_1, dd_Smed_v6_19189_0_1, [Score=670, Expect=0.0]} {RNA1509_46639} {RNA1310_1412.2} {RNA815_15650}
46. MligTC455_19126 10 0.2 Mlig455_009225

Neo: -

Age: -

1.909 - 0.937 0.972 - - - Mlig455_009225 {REF} {Length: 1570} {Pfam: Galactosyltransferase [PF01762.23, score=21.4]} {Mouse: ENSMUSG00000031803, B3gnt3, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, [Score=50.4, Expect=1e-06]} {RNA1310_57689} {RNA815_57743}
47. MligTC455_44954 1303 27.14 Mlig455_029595, Mlig455_070648

Neo: Int S/G2/M

Age: Down-Up-Up, logFC(26M/2M)=1.023

Region-specific R2: 8.846

Region-enriched R2: 10.764/0.00000

1.902 - - 0.973 - 0.929 -

Mlig455_029595 {REF} {Length: 484} {Pfam: Pancreatic hormone peptide [PF00159.20, score=30.3]} {Smed: dd_Smed_v6_6375_0_1, dd_Smed_v6_6375_0_1, [RH, Score=47.4, Expect=3e-08]} {RNA1509_20871} {RNA1310_66833.2} {RNA815_41767}

Mlig455_070648 {REF} {Length: 484} {Pfam: Pancreatic hormone peptide [PF00159.20, score=30.3]} {Smed: dd_Smed_v6_6375_0_1, dd_Smed_v6_6375_0_1, [RH, Score=47.4, Expect=3e-08]} {RNA1509_20871, RNA1509_39484} {RNA1310_66833.2, RNA1509_20871, RNA1509_39484} {RNA1509_20871, RNA1509_39484, RNA815_41767}
48. MligTC455_50410 31 0.64 Mlig455_020239

Neo: -

Age: -

GRIA2 1.899 - - 0.989 - 0.910 - Mlig455_020239 {REF} {Length: 2096} {Pfam: Ligand-gated ion channel [PF00060.28, score=192.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=127.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=91.1]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=513, Expect=7e-173]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=496, Expect=3e-166]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=494, Expect=8e-167]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=491, Expect=1e-164]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=507, Expect=4e-171]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=497, Expect=4e-167]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=494, Expect=1e-165]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=491, Expect=1e-164]} {Dmel: FBgn0038837, CG3822, [Score=432, Expect=1e-142]} {Celegans: WBGene00001612, glr-1, Glutamate receptor 1, [Score=459, Expect=5e-152]} {Smed: dd_Smed_v6_7562_0_1, dd_Smed_v6_7562_0_1, [Score=528, Expect=2e-179]} {RNA1509_56139} {RNA1310_38868} {RNA815_32684}
49. MligTC455_15183 10 0.2 Mlig455_018461

Neo: -

Age: Down-Up-Down

SCNN1A 1.897 - - 0.972 - 0.925 - Mlig455_018461 {REF} {Length: 2620} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=183.7]} {Human: ENSG00000111319, SCNN1A, sodium channel epithelial 1 alpha subunit, [Score=67.8, Expect=4e-11]} {Mouse: ENSMUSG00000030340, Scnn1a, sodium channel, nonvoltage-gated 1 alpha, [Score=55.5, Expect=6e-08]} {Celegans: WBGene00009073, delm-1, DEgenerin Linked to Mechanosensation, [Score=68.9, Expect=5e-12]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [RH, Score=125, Expect=3e-30]} {RNA1310_11413} {RNA815_11497}
50. MligTC455_42240 80 1.66 Mlig455_038267

Neo: -

Age: Down-Up-Down

1.897 - 0.951 - - 0.946 - Mlig455_038267 {REF} {Length: 989} {RNA1310_36501} {RNA815_32545}
51. MligTC455_32521 203 4.23 Mlig455_040932

Neo: -

Age: Down-Down-Up

Region-enriched R8: 3.877/0.00012
Region-enriched R2: 3.007/0.00212

1.895 - - 0.980 - 0.915 - Mlig455_040932 {REF} {Length: 1862} {RNA1310_21335.1} {RNA815_57481}
52. MligTC455_40649 24 0.49 Mlig455_066232

Neo: -

Age: -

1.895 - 0.914 0.981 - - - Mlig455_066232 {REF} {Length: 2453} {RNA1310_42980.1} {RNA815_47590}
53. MligTC455_00067 6 0.13 Mlig455_035302

Neo: -

Age: -

1.894 - - 0.964 - 0.930 - Mlig455_035302 {REF} {Length: 1437}
54. MligTC455_19225 26 0.54 Mlig455_018507

Neo: -

Age: -

SCNN1B 1.894 - 0.984 0.910 - - - Mlig455_018507 {REF} {Length: 2590} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=142.8]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=59.3, Expect=1e-08]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=60.8, Expect=1e-09]} {Smed: dd_Smed_v6_17245_0_1, dd_Smed_v6_17245_0_1, [Score=49.3, Expect=5e-06]} {RNA1509_52685} {RNA1310_32081} {RNA815_49764}
55. MligTC455_29261 34 0.71 Mlig455_024258

Neo: -

Age: -

1.893 - - 0.972 - 0.921 - Mlig455_024258 {REF} {Length: 1171} {RNA1509_25125} {RNA1310_234.1} {RNA815_23.1}
56. MligTC455_05183 13 0.27 Mlig455_003637

Neo: -

Age: -

1.892 - - 0.974 - 0.918 - Mlig455_003637 {REF} {Length: 906} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_38541_0_1, dd_Smed_v6_38541_0_1, [Score=57.0, Expect=8e-10]} {RNA1310_45613} {RNA815_17816.1}
57. MligTC455_14898 41 0.86 Mlig455_011988

Neo: -

Age: -

1.89 - - 0.972 - 0.918 - Mlig455_011988 {REF} {Length: 858} {Pfam: Lectin C-type domain [PF00059.23, score=28.2]} {RNA1509_20946} {RNA1310_48952} {RNA815_4785.1}
58. MligTC455_44159 80 1.67 Mlig455_019040, Mlig455_055663

Neo: -

Age: Down-Up-Up

ADRB1, GALR3 1.888 - - 0.975 - 0.913 -

Mlig455_019040 {REF} {Length: 1804} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=78.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=31.3]} {Human: ENSG00000043591, ADRB1, adrenoceptor beta 1, [Score=52.8, Expect=5e-07]} {Mouse: ENSMUSG00000034987, Hrh2, histamine receptor H2, [Score=47.8, Expect=1e-05]} {Dmel: FBgn0038874, ETHR, [Score=49.3, Expect=3e-06]} {Celegans: WBGene00017661, frpr-6, FMRFamide Peptide Receptor family, [Score=54.3, Expect=5e-08]} {Smed: dd_Smed_v6_19933_0_1, dd_Smed_v6_19933_0_1, [RH, Score=124, Expect=9e-33]} {RNA1310_47955} {RNA815_45615}

Mlig455_055663 {REF} {Length: 1667} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=47.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=27.2]} {Human: ENSG00000128310, GALR3, galanin receptor 3, [Score=50.1, Expect=2e-06]} {Smed: dd_Smed_v6_14726_0_1, dd_Smed_v6_14726_0_1, [Score=103, Expect=6e-25]} {RNA1310_86586} {RNA815_45615}
59. MligTC455_48692 15 0.32 Mlig455_021398

Neo: -

Age: -

Region-enriched R2: 8.096/0.02429

1.888 - - 0.972 - 0.916 - Mlig455_021398 {REF} {Length: 1571} {Pfam: Ankyrin repeat [PF00023.32, score=20.9]; Ankyrin repeats (many copies) [PF13637.8, score=20.4]; Ankyrin repeats (many copies) [PF13857.8, score=19.6]; Ankyrin repeats (3 copies) [PF12796.9, score=19.4]} {Smed: dd_Smed_v6_29956_0_1, dd_Smed_v6_29956_0_1, [Score=54.7, Expect=3e-08]} {RNA1310_69005}
60. MligTC455_09416 15 0.32 Mlig455_025505, Mlig455_025526

Neo: -

Age: -

HRH1 1.884 - 0.950 0.934 - - -

Mlig455_025505 {REF} {Length: 1843} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=122.8]} {Human: ENSG00000196639, HRH1, histamine receptor H1, [Score=131, Expect=4e-34]} {Mouse: ENSMUSG00000053004, Hrh1, histamine receptor H1, [Score=127, Expect=9e-33]} {Dmel: FBgn0000037, mAChR-A, muscarinic Acetylcholine Receptor, A-type, [Score=113, Expect=2e-27]} {Celegans: WBGene00006475, tyra-3, TYRAmine receptor, [Score=102, Expect=4e-24]} {Smed: dd_Smed_v6_15040_0_1, dd_Smed_v6_15040_0_1, [Score=99.4, Expect=4e-23]} {RNA1509_53354} {RNA1310_79526} {RNA815_31150}

Mlig455_025526 {REF} {Length: 2045} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=247.0]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=30.1]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=25.8]; Olfactory receptor [PF13853.8, score=23.3]} {Human: ENSG00000196639, HRH1, histamine receptor H1, [RH, Score=264, Expect=2e-82]} {Mouse: ENSMUSG00000053004, Hrh1, histamine receptor H1, [RH, Score=264, Expect=2e-82]} {Dmel: FBgn0004514, Oct-TyrR, Octopamine-Tyramine receptor, [Score=192, Expect=2e-54]} {Celegans: WBGene00006475, tyra-3, TYRAmine receptor, [Score=187, Expect=4e-53]} {Smed: dd_Smed_v6_48706_0_1, dd_Smed_v6_48706_0_1, [Score=189, Expect=2e-55]} {RNA1509_53354} {RNA1310_79526} {RNA815_31150}
61. MligTC455_11558 137 2.85 Mlig455_058259

Neo: -

Age: logFC(26M/2M)=-0.792

1.883 - - 0.965 - 0.918 - Mlig455_058259 {REF} {Length: 896} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=19.9]} {RNA1509_58923} {RNA1310_41706, RNA1509_58923} {RNA1509_58923, RNA815_20876}
62. MligTC455_23825 29 0.6 Mlig455_002166, Mlig455_002310

Neo: -

Age: Down-Up-Down

NOL4 1.882 - - 0.964 - 0.918 -

Mlig455_002166 {REF} {Length: 3243} {Human: ENSG00000101746, NOL4, nucleolar protein 4, [RH, Score=135, Expect=9e-35]} {Mouse: ENSMUSG00000041923, Nol4, nucleolar protein 4, [RH, Score=136, Expect=1e-34]} {Dmel: FBgn0283651, CG46301, [RH, Score=140, Expect=4e-35]} {Smed: dd_Smed_v6_10255_0_1, dd_Smed_v6_10255_0_1, [RH, Score=82.4, Expect=6e-17]} {RNA1509_41791} {RNA1310_36173.1} {RNA815_37287}

Mlig455_002310 {REF} {Length: 2667} {Human: ENSG00000101746, NOL4, nucleolar protein 4, [RH, Score=135, Expect=1e-34]} {Mouse: ENSMUSG00000041923, Nol4, nucleolar protein 4, [RH, Score=136, Expect=1e-34]} {Dmel: FBgn0283651, CG46301, [RH, Score=140, Expect=4e-35]} {Smed: dd_Smed_v6_10255_0_1, dd_Smed_v6_10255_0_1, [RH, Score=82.4, Expect=6e-17]} {RNA1509_41791} {RNA1310_36173.1}
63. MligTC455_47997 36 0.75 Mlig455_053262, Mlig455_065031

Neo: -

Age: -

1.879 - 0.997 0.882 - - -

Mlig455_053262 {REF} {Length: 927} {RNA1310_55950} {RNA815_42062.2}

Mlig455_065031 {REF} {Length: 926} {RNA1310_55950} {RNA815_42062.2}
64. MligTC455_36194 30 0.61 Mlig455_064360, Mlig455_064382

Neo: -

Age: -

B3GNT4 1.876 - - 0.973 - 0.903 -

Mlig455_064360 {REF} {Length: 3119} {Pfam: Galactosyltransferase [PF01762.23, score=116.7]} {Human: ENSG00000176383, B3GNT4, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, [Score=101, Expect=5e-23]} {Mouse: ENSMUSG00000031803, B3gnt3, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, [Score=94.7, Expect=9e-21]; ENSMUSG00000051650, B3gnt2, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, [Score=94.0, Expect=2e-20]; ENSMUSG00000067370, B3galt4, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4, [Score=93.6, Expect=3e-20]; ENSMUSG00000029431, B3gnt4, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, [Score=93.2, Expect=2e-20]; ENSMUSG00000022686, B3gnt5, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5, [Score=91.7, Expect=1e-19]} {Dmel: FBgn0031988, CG8668, [Score=90.1, Expect=8e-19]} {Celegans: WBGene00007104, B0024.15, Hexosyltransferase, [RH, Score=90.9, Expect=8e-20]} {Smed: dd_Smed_v6_9789_0_1, dd_Smed_v6_9789_0_1, [Score=165, Expect=5e-47]} {RNA1310_43172} {RNA815_26726}

Mlig455_064382 {REF} {Length: 3084} {Pfam: Galactosyltransferase [PF01762.23, score=116.7]} {Human: ENSG00000176383, B3GNT4, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, [Score=101, Expect=5e-23]} {Mouse: ENSMUSG00000031803, B3gnt3, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, [Score=94.7, Expect=9e-21]; ENSMUSG00000051650, B3gnt2, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, [Score=94.4, Expect=2e-20]; ENSMUSG00000029431, B3gnt4, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, [Score=93.6, Expect=2e-20]; ENSMUSG00000067370, B3galt4, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4, [Score=93.6, Expect=2e-20]; ENSMUSG00000022686, B3gnt5, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5, [Score=92.0, Expect=9e-20]} {Dmel: FBgn0031988, CG8668, [Score=90.1, Expect=8e-19]} {Celegans: WBGene00007104, B0024.15, Hexosyltransferase, [RH, Score=90.9, Expect=8e-20]} {Smed: dd_Smed_v6_9789_0_1, dd_Smed_v6_9789_0_1, [Score=165, Expect=5e-47]} {RNA1310_43172} {RNA815_26726}
65. MligTC455_12867 14 0.29 Mlig455_049571

Neo: -

Age: -

KCNIP3 1.874 - - 0.969 - 0.905 - Mlig455_049571 {REF} {Length: 1857} {Pfam: EF-hand domain pair [PF13499.8, score=50.8]; EF hand [PF00036.34, score=44.5]; EF-hand domain [PF13405.8, score=39.6]; EF-hand domain pair [PF13833.8, score=32.7]; EF hand [PF13202.8, score=30.8]} {Human: ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=155, Expect=4e-44]; ENSG00000120049, KCNIP2, potassium voltage-gated channel interacting protein 2, [Score=148, Expect=1e-41]} {Mouse: ENSMUSG00000025221, Kcnip2, Kv channel-interacting protein 2, [Score=146, Expect=4e-41]; ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=140, Expect=7e-39]} {Dmel: FBgn0265595, CG44422, [Score=154, Expect=3e-42]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=125, Expect=1e-33]} {Smed: dd_Smed_v6_9434_0_1, dd_Smed_v6_9434_0_1, [Score=127, Expect=2e-34]} {RNA1310_70106} {RNA815_36691}
66. MligTC455_14043 12 0.26 Mlig455_016776

Neo: -

Age: -

ANKRD63 1.873 - - 0.974 - 0.899 - Mlig455_016776 {REF} {Length: 1715} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=122.1]; Ankyrin repeats (many copies) [PF13637.8, score=70.6]; Ankyrin repeats (many copies) [PF13857.8, score=54.8]; Ankyrin repeat [PF00023.32, score=50.2]; Ankyrin repeat [PF13606.8, score=43.7]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [RH, Score=130, Expect=1e-33]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [RH, Score=131, Expect=9e-34]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=66.2, Expect=3e-11]} {Celegans: WBGene00012124, T28D6.4, [Score=62.8, Expect=3e-10]} {Smed: dd_Smed_v6_11187_0_3, dd_Smed_v6_11187_0_3, [Score=56.6, Expect=2e-08]} {RNA815_38023}
67. MligTC455_26200 12 0.26 Mlig455_068734

Neo: -

Age: -

TNXB 1.873 - - 0.955 - 0.918 - Mlig455_068734 {REF} {Length: 1237} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=176.4]} {Human: ENSG00000229353, TNXB, tenascin XB, [RH, Score=133, Expect=3e-34]; ENSG00000236236, TNXB, tenascin XB, [RH, Score=132, Expect=6e-34]; ENSG00000168477, TNXB, tenascin XB, [RH, Score=132, Expect=6e-34]} {Mouse: ENSMUSG00000033327, Tnxb, tenascin XB, [Score=131, Expect=8e-34]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=129, Expect=5e-34]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=128, Expect=1e-33]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=127, Expect=5e-33]} {Dmel: FBgn0033312, CG8642, [Score=110, Expect=2e-27]} {Celegans: WBGene00020516, T15B7.1, [Score=61.6, Expect=1e-10]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=113, Expect=4e-28]} {RNA1310_44670.1} {RNA815_23388}
68. MligTC455_35503 32 0.66 Mlig455_009758, Mlig455_070115

Neo: -

Age: -

HMX3 1.873 - 0.910 0.963 - - -

Mlig455_009758 {REF} {Length: 2090} {Pfam: Homeodomain [PF00046.31, score=72.3]} {Human: ENSG00000188620, HMX3, H6 family homeobox 3, [RH, Score=163, Expect=1e-44]} {Mouse: ENSMUSG00000040148, Hmx3, H6 homeobox 3, [RH, Score=162, Expect=2e-44]; ENSMUSG00000067438, Hmx1, H6 homeobox 1, [RH, Score=155, Expect=4e-42]} {Dmel: FBgn0011758, B-H1, BarH1, [Score=102, Expect=1e-22]} {Celegans: WBGene00003377, mls-2, Mesodermal Lineage Specification, [RH, Score=113, Expect=2e-27]} {Smed: dd_Smed_v6_52497_0_1, dd_Smed_v6_52497_0_1, [RH, Score=150, Expect=4e-42]}

Mlig455_070115 {REF} {Length: 2868} {Pfam: Homeodomain [PF00046.31, score=72.2]} {Human: ENSG00000188620, HMX3, H6 family homeobox 3, [RH, Score=163, Expect=6e-45]} {Mouse: ENSMUSG00000040148, Hmx3, H6 homeobox 3, [RH, Score=162, Expect=1e-44]; ENSMUSG00000067438, Hmx1, H6 homeobox 1, [RH, Score=155, Expect=3e-42]} {Dmel: FBgn0011758, B-H1, BarH1, [Score=102, Expect=9e-23]} {Celegans: WBGene00003377, mls-2, Mesodermal Lineage Specification, [RH, Score=113, Expect=1e-27]} {Smed: dd_Smed_v6_52497_0_1, dd_Smed_v6_52497_0_1, [RH, Score=151, Expect=2e-42]} {RNA1310_148861}
69. MligTC455_39719 44 0.92 Mlig455_063602

Neo: -

Age: -

MPDZ 1.873 - - 0.984 - 0.889 - Mlig455_063602 {REF} {Length: 2307} {Pfam: PDZ domain [PF00595.26, score=187.6]; PDZ domain [PF17820.3, score=85.4]; PDZ domain [PF13180.8, score=85.1]} {Human: ENSG00000107186, MPDZ, multiple PDZ domain crumbs cell polarity complex component, [Score=244, Expect=9e-70]} {Mouse: ENSMUSG00000028402, Mpdz, multiple PDZ domain protein, [Score=237, Expect=7e-67]} {Dmel: FBgn0263289, scrib, scribbled, [Score=88.6, Expect=6e-18]} {Celegans: WBGene00003404, mpz-1, Multiple PDZ domain protein, [Score=137, Expect=7e-35]} {Smed: dd_Smed_v6_4520_0_1, dd_Smed_v6_4520_0_1, [Score=147, Expect=2e-37]} {RNA1310_8275.3} {RNA815_16615}
70. MligTC455_14172 11 0.22 Mlig455_042536

Neo: -

Age: -

STON2 1.871 - - 0.955 - 0.916 - Mlig455_042536 {REF} {Length: 4650} {Pfam: Adaptor complexes medium subunit family [PF00928.23, score=54.1]} {Human: ENSG00000140022, STON2, stonin 2, [Score=131, Expect=3e-30]} {Mouse: ENSMUSG00000020961, Ston2, stonin 2, [Score=132, Expect=1e-30]} {Dmel: FBgn0016975, stnB, stoned B, [Score=142, Expect=6e-34]} {Celegans: WBGene00006777, unc-41, Putative stoned B-like protein, [Score=155, Expect=6e-38]} {Smed: dd_Smed_v6_6859_0_1, dd_Smed_v6_6859_0_1, [Score=221, Expect=2e-58]} {RNA1310_91122}
71. MligTC455_16646 14 0.29 Mlig455_038608

Neo: -

Age: -

HTR1A 1.869 - - 0.963 - 0.906 - Mlig455_038608 {REF} {Length: 1523} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=49.9]} {Human: ENSG00000178394, HTR1A, 5-hydroxytryptamine receptor 1A, [Score=71.6, Expect=7e-16]} {Mouse: ENSMUSG00000021721, Htr1a, 5-hydroxytryptamine (serotonin) receptor 1A, [Score=68.2, Expect=7e-15]; ENSMUSG00000022705, Drd3, dopamine receptor D3, [Score=65.1, Expect=9e-14]} {Dmel: FBgn0038063, Octbeta2R, Octopamine beta2 receptor, [Score=72.0, Expect=3e-16]} {Celegans: WBGene00016872, dop-4, Dopamine receptor 4, [Score=60.8, Expect=1e-12]} {Smed: dd_Smed_v6_31134_0_1, dd_Smed_v6_31134_0_1, [Score=118, Expect=3e-33]} {RNA1509_58224} {RNA1310_114359} {RNA815_11051.1}
72. MligTC455_16329 1019 21.23 Mlig455_007993

Neo: -

Age: -

Region-specific R2: 3.685

Region-enriched R2: 3.576/0.00000
Region-enriched R7: 1.704/0.00652

1.868 - - 0.966 - 0.902 - Mlig455_007993 {REF} {Length: 635} {RNA1509_22236} {RNA1310_84275, RNA1509_22236} {RNA1509_22236, RNA815_43046}
73. MligTC455_33046 67 1.4 Mlig455_013269, Mlig455_032133, Mlig455_032300, Mlig455_054137, Mlig455_056421, Mlig455_065759

Neo: -

Age: Up-Down-Down

1.868 - - 0.972 - 0.896 -

Mlig455_013269 {REF} {Length: 847} {Pfam: Recombination endonuclease VII [PF02945.17, score=31.7]} {Celegans: WBGene00016348, C33E10.6, [Score=80.9, Expect=4e-17]} {Smed: dd_Smed_v6_9974_1_5, dd_Smed_v6_9974_1_5, [Score=93.6, Expect=1e-21]} {RNA1509_39151} {RNA1310_2387} {RNA815_59939}

Mlig455_032133 {REF} {Length: 905} {Pfam: Recombination endonuclease VII [PF02945.17, score=32.0]; Borrelia P83/100 protein [PF05262.13, score=18.2]} {Celegans: WBGene00016348, C33E10.6, [Score=82.0, Expect=4e-17]} {Smed: dd_Smed_v6_9974_1_2, dd_Smed_v6_9974_1_2, [Score=95.9, Expect=6e-22]} {RNA1509_39151} {RNA1310_2387} {RNA815_59939}

Mlig455_032300 {REF} {Length: 1525} {Pfam: Borrelia P83/100 protein [PF05262.13, score=21.0]; Phosphatidylinositol-4-phosphate 5-Kinase [PF01504.20, score=19.4]; Contractile injection system tape measure protein [PF19268.1, score=18.6]} {RNA1509_13774} {RNA1310_41660} {RNA815_55778}

Mlig455_054137 {REF} {Length: 899} {Pfam: Recombination endonuclease VII [PF02945.17, score=31.1]} {Celegans: WBGene00016348, C33E10.6, [Score=80.1, Expect=1e-16]} {Smed: dd_Smed_v6_9974_1_2, dd_Smed_v6_9974_1_2, [Score=111, Expect=3e-27]} {RNA1509_39151} {RNA1310_2387} {RNA815_19338}

Mlig455_056421 {REF} {Length: 1944} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=21.4]} {Smed: dd_Smed_v6_14361_0_10, dd_Smed_v6_14361_0_10, [Score=51.2, Expect=7e-09]} {RNA1509_21624} {RNA1310_2387} {RNA815_19338}

Mlig455_065759 {REF} {Length: 1453} {Pfam: Recombination endonuclease VII [PF02945.17, score=30.3]} {Celegans: WBGene00016348, C33E10.6, [Score=101, Expect=9e-23]} {Smed: dd_Smed_v6_9974_1_2, dd_Smed_v6_9974_1_2, [Score=142, Expect=2e-36]} {RNA1509_39151} {RNA1310_2387} {RNA815_19338}
74. MligTC455_21178 29 0.59 Mlig455_001203, Mlig455_066754, Mlig455_069710

Neo: -

Age: Down-Up-Down

CCKAR, NPFFR1 1.867 - 0.967 0.900 - - -

Mlig455_001203 {REF} {Length: 4789} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=109.9]} {Human: ENSG00000163394, CCKAR, cholecystokinin A receptor, [Score=60.5, Expect=3e-09]; ENSG00000148734, NPFFR1, neuropeptide FF receptor 1, [Score=58.5, Expect=9e-09]} {Mouse: ENSMUSG00000020090, Npffr1, neuropeptide FF receptor 1, [Score=59.3, Expect=3e-09]; ENSMUSG00000019865, Nmbr, neuromedin B receptor, [Score=58.2, Expect=4e-09]; ENSMUSG00000029193, Cckar, cholecystokinin A receptor, [Score=56.6, Expect=3e-08]; ENSMUSG00000035528, Npffr2, neuropeptide FF receptor 2, [Score=56.6, Expect=2e-08]} {Dmel: FBgn0038542, TyrR, Tyramine receptor, [Score=65.5, Expect=4e-11]} {Celegans: WBGene00004778, ser-3, SERotonin/octopamine receptor family, [Score=58.5, Expect=5e-09]} {Smed: dd_Smed_v6_43180_0_1, dd_Smed_v6_43180_0_1, [Score=72.4, Expect=4e-14]} {RNA1310_113134}

Mlig455_066754 {REF} {Length: 3197} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=84.3]} {Human: ENSG00000148734, NPFFR1, neuropeptide FF receptor 1, [Score=52.8, Expect=6e-07]} {Mouse: ENSMUSG00000020090, Npffr1, neuropeptide FF receptor 1, [Score=54.7, Expect=1e-07]} {Dmel: FBgn0038542, TyrR, Tyramine receptor, [Score=53.5, Expect=2e-07]} {Celegans: WBGene00006428, tkr-3, TachyKinin Receptor family, [Score=50.1, Expect=1e-06]} {Smed: dd_Smed_v6_16725_0_1, dd_Smed_v6_16725_0_1, [Score=52.8, Expect=2e-07]} {RNA1310_131269}

Mlig455_069710 {REF} {Length: 1208} {NoTransDecoderORF} {RNA1310_131269}
75. MligTC455_07512 15 0.3 Mlig455_049171

Neo: -

Age: Down-Up-Up

GRIA1 1.864 - - 0.974 - 0.890 - Mlig455_049171 {REF} {Length: 3290} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=124.7]; Ligand-gated ion channel [PF00060.28, score=121.8]; Receptor family ligand binding region [PF01094.30, score=86.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=66.8]} {Human: ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=446, Expect=9e-142]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=432, Expect=2e-136]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=431, Expect=8e-136]} {Mouse: ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=446, Expect=5e-142]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=432, Expect=1e-136]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=427, Expect=7e-135]} {Dmel: FBgn0038837, CG3822, [Score=392, Expect=4e-122]} {Celegans: WBGene00001612, glr-1, Glutamate receptor 1, [Score=352, Expect=4e-106]} {Smed: dd_Smed_v6_7562_0_1, dd_Smed_v6_7562_0_1, [Score=554, Expect=0.0]} {RNA1509_56139} {RNA1310_34593} {RNA815_47410}
76. MligTC455_19524 100 2.09 Mlig455_010263

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.437/0.01311

1.859 - 0.897 0.962 - - - Mlig455_010263 {REF} {Length: 2969} {RNA1310_11925.1} {RNA815_27110}
77. MligTC455_13866 60 1.26 Mlig455_059198

Neo: -

Age: -

1.858 - - 0.955 - 0.903 - Mlig455_059198 {REF} {Length: 561} {NoTransDecoderORF} {RNA1310_89423} {RNA815_50610}
78. MligTC455_15884 26 0.54 Mlig455_066451

Neo: -

Age: -

Region-enriched R2: 9.632/0.00394

1.857 - 0.999 - - 0.858 - Mlig455_066451 {REF} {Length: 1468} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=20.9]} {RNA1310_27849} {RNA815_37376}
79. MligTC455_20643 34 0.72 Mlig455_066722

Neo: -

Age: -

CHRNA6 1.854 - - 0.956 - 0.898 - Mlig455_066722 {REF} {Length: 3504} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=224.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=197.3]} {Human: ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=357, Expect=6e-118]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=355, Expect=6e-117]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=352, Expect=1e-115]; ENSG00000169684, CHRNA5, cholinergic receptor nicotinic alpha 5 subunit, [Score=340, Expect=1e-111]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=340, Expect=1e-111]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=358, Expect=2e-118]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=355, Expect=3e-117]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=345, Expect=4e-113]; ENSMUSG00000027950, Chrnb2, cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal), [Score=341, Expect=1e-111]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=435, Expect=1e-148]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=371, Expect=8e-124]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=570, Expect=0.0]} {RNA1509_52151} {RNA1310_16118} {RNA815_53101}
80. MligTC455_14917 71 1.49 Mlig455_035669, Mlig455_035765

Neo: -

Age: -

ADRA1A 1.847 - - - - 0.978 0.869

Mlig455_035669 {REF} {Length: 1803} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=108.7]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=42.4]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.2]; Serpentine type 7TM GPCR chemoreceptor Srz [PF10325.11, score=21.2]; Olfactory receptor [PF13853.8, score=20.9]} {Human: ENSG00000120907, ADRA1A, adrenoceptor alpha 1A, [Score=83.2, Expect=1e-16]; ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=79.7, Expect=1e-15]} {Mouse: ENSMUSG00000028778, Hcrtr1, hypocretin (orexin) receptor 1, [Score=85.1, Expect=1e-17]; ENSMUSG00000045875, Adra1a, adrenergic receptor, alpha 1a, [Score=84.7, Expect=3e-17]; ENSMUSG00000032360, Hcrtr2, hypocretin (orexin) receptor 2, [Score=84.0, Expect=4e-17]} {Dmel: FBgn0038874, ETHR, [Score=115, Expect=4e-28]} {Celegans: WBGene00016265, trhr-1, Thyrotropin-Releasing Hormone Receptor, [Score=76.6, Expect=5e-15]} {Smed: dd_Smed_v6_18312_0_1, dd_Smed_v6_18312_0_1, [Score=73.2, Expect=6e-14]} {RNA1310_81509} {RNA815_63181}

Mlig455_035765 {REF} {Length: 1803} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=108.5]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=42.4]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.2]; Serpentine type 7TM GPCR chemoreceptor Srz [PF10325.11, score=21.2]; Olfactory receptor [PF13853.8, score=20.9]} {Human: ENSG00000120907, ADRA1A, adrenoceptor alpha 1A, [Score=82.8, Expect=1e-16]; ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=80.1, Expect=1e-15]} {Mouse: ENSMUSG00000028778, Hcrtr1, hypocretin (orexin) receptor 1, [Score=86.3, Expect=5e-18]; ENSMUSG00000045875, Adra1a, adrenergic receptor, alpha 1a, [Score=84.3, Expect=4e-17]; ENSMUSG00000032360, Hcrtr2, hypocretin (orexin) receptor 2, [Score=83.6, Expect=5e-17]} {Dmel: FBgn0038874, ETHR, [Score=115, Expect=5e-28]} {Celegans: WBGene00016265, trhr-1, Thyrotropin-Releasing Hormone Receptor, [Score=76.3, Expect=6e-15]} {Smed: dd_Smed_v6_18312_0_1, dd_Smed_v6_18312_0_1, [Score=72.0, Expect=1e-13]} {RNA1310_81509} {RNA815_63181}
81. MligTC455_27918 42 0.87 Mlig455_004025, Mlig455_004105, Mlig455_039294

Neo: -

Age: Down-Up-Up

1.847 - - 0.960 - 0.887 -

Mlig455_004025 {REF} {Length: 2650} {RNA1310_16141} {RNA815_7007}

Mlig455_004105 {REF} {Length: 1268} {RNA1310_85247} {RNA815_59251}

Mlig455_039294 {REF} {Length: 2639} {RNA1310_16141} {RNA815_7007}
82. MligTC455_18955 13 0.27 Mlig455_047126

Neo: -

Age: -

1.846 - - 0.972 - 0.874 - Mlig455_047126 {REF} {Length: 1058}
83. MligTC455_46543 178 3.7 Mlig455_000344, Mlig455_067946

Neo: -

Age: -

Region-specific R2: 6.098

Region-enriched R2: 6.851/0.00000

1.846 - - 0.957 - 0.889 -

Mlig455_000344 {REF} {Length: 1920} {RNA1310_82457} {RNA815_33120}

Mlig455_067946 {REF} {Length: 1217} {RNA1310_99435}
84. MligTC455_50643 38 0.8 Mlig455_007952, Mlig455_008053

Neo: -

Age: -

VSX1 1.845 - 0.952 0.893 - - -

Mlig455_007952 {REF} {Length: 1358} {Pfam: Homeodomain [PF00046.31, score=79.6]} {Human: ENSG00000100987, VSX1, visual system homeobox 1, [RH, Score=197, Expect=4e-60]; ENSG00000119614, VSX2, visual system homeobox 2, [RH, Score=196, Expect=2e-59]} {Mouse: ENSMUSG00000021239, Vsx2, visual system homeobox 2, [RH, Score=196, Expect=6e-60]; ENSMUSG00000033080, Vsx1, visual system homeobox 1, [RH, Score=195, Expect=2e-59]} {Dmel: FBgn0263512, Vsx2, Visual system homeobox 2, [RH, Score=204, Expect=3e-60]} {Celegans: WBGene00000435, ceh-10, Homeobox protein ceh-10, [RH, Score=204, Expect=2e-63]} {Smed: dd_Smed_v6_19286_0_1, dd_Smed_v6_19286_0_1, [RH, Score=211, Expect=2e-66]} {RNA1310_76393} {RNA815_51313}

Mlig455_008053 {REF} {Length: 2271} {RNA1310_76393} {RNA815_51313}
85. MligTC455_53821 8 0.17 Mlig455_001156, Mlig455_001317

Neo: -

Age: -

1.842 - 0.954 - - 0.888 -

Mlig455_001156 {REF} {Length: 2464} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=45.5]} {Smed: dd_Smed_v6_42389_0_1, dd_Smed_v6_42389_0_1, [Score=124, Expect=9e-33]} {RNA1310_149146}

Mlig455_001317 {REF} {Length: 2243} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=21.1]} {Smed: dd_Smed_v6_11577_0_1, dd_Smed_v6_11577_0_1, [Score=67.4, Expect=8e-13]} {RNA1310_149146}
86. MligTC455_50777 40 0.83 Mlig455_042072

Neo: -

Age: -

MTNR1B 1.84 - - 0.966 - 0.874 - Mlig455_042072 {REF} {Length: 2881} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=78.0]; Olfactory receptor [PF13853.8, score=24.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=22.0]} {Human: ENSG00000134640, MTNR1B, melatonin receptor 1B, [Score=94.4, Expect=2e-21]; ENSG00000168412, MTNR1A, melatonin receptor 1A, [Score=90.1, Expect=5e-20]} {Mouse: ENSMUSG00000050901, Mtnr1b, melatonin receptor 1B, [Score=94.0, Expect=2e-21]; ENSMUSG00000054764, Mtnr1a, melatonin receptor 1A, [Score=89.4, Expect=6e-20]} {Dmel: FBgn0004514, Oct-TyrR, Octopamine-Tyramine receptor, [Score=57.0, Expect=7e-09]} {Celegans: WBGene00006428, tkr-3, TachyKinin Receptor family, [Score=52.0, Expect=2e-07]} {Smed: dd_Smed_v6_19535_0_1, dd_Smed_v6_19535_0_1, [Score=95.5, Expect=2e-22]} {RNA1310_66047} {RNA815_34066}
87. MligTC455_50602 84 1.74 Mlig455_065088

Neo: -

Age: -

1.839 - - 0.974 - 0.865 - Mlig455_065088 {REF} {Length: 2765} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=129.5]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [Score=67.8, Expect=6e-12]} {RNA1310_8235} {RNA815_10456.1}
88. MligTC455_19412 42 0.88 Mlig455_047997

Neo: -

Age: -

1.837 - 0.882 0.955 - - - Mlig455_047997 {REF} {Length: 701} {RNA1310_53549} {RNA815_27051}
89. MligTC455_38667 17 0.35 Mlig455_059621

Neo: -

Age: -

1.837 - - 0.974 - 0.863 - Mlig455_059621 {REF} {Length: 1297} {RNA1310_51041}
90. MligTC455_12886 7 0.15 Mlig455_062770

Neo: -

Age: -

1.836 - 0.978 0.858 - - - Mlig455_062770 {REF} {Length: 486} {RNA1310_94667}
91. MligTC455_25701 31 0.65 Mlig455_017477

Neo: -

Age: -

1.835 - - 0.951 - 0.884 - Mlig455_017477 {REF} {Length: 664} {RNA1310_52753} {RNA815_26527}
92. MligTC455_50778 36 0.76 Mlig455_042296

Neo: -

Age: -

GPR50 1.832 - - 0.965 - 0.867 - Mlig455_042296 {REF} {Length: 1415} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=116.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=40.0]; Olfactory receptor [PF13853.8, score=34.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=33.9]} {Human: ENSG00000102195, GPR50, G protein-coupled receptor 50, [Score=124, Expect=4e-31]; ENSG00000134640, MTNR1B, melatonin receptor 1B, [Score=119, Expect=2e-30]} {Mouse: ENSMUSG00000054764, Mtnr1a, melatonin receptor 1A, [Score=120, Expect=4e-31]; ENSMUSG00000056380, Gpr50, G-protein-coupled receptor 50, [Score=119, Expect=2e-29]; ENSMUSG00000050901, Mtnr1b, melatonin receptor 1B, [Score=118, Expect=5e-30]} {Dmel: FBgn0038980, Octbeta1R, Octopamine beta1 receptor, [Score=92.0, Expect=1e-20]} {Celegans: WBGene00006428, tkr-3, TachyKinin Receptor family, [Score=69.7, Expect=4e-13]} {Smed: dd_Smed_v6_65999_0_1, dd_Smed_v6_65999_0_1, [Score=84.7, Expect=1e-18]} {RNA1310_66047} {RNA815_34066}
93. MligTC455_37195 68 1.41 Mlig455_033638, Mlig455_033665

Neo: -

Age: Up-Down-Down

ASIC1 1.83 - 0.852 0.978 - - -

Mlig455_033638 {REF} {Length: 3007} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=199.6]} {Human: ENSG00000110881, ASIC1, acid sensing ion channel subunit 1, [Score=60.8, Expect=4e-09]} {Mouse: ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=55.8, Expect=1e-07]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=67.8, Expect=1e-11]} {Smed: dd_Smed_v6_19599_0_1, dd_Smed_v6_19599_0_1, [RH, Score=483, Expect=5e-165]} {RNA1509_46829} {RNA1310_13649} {RNA815_15065}

Mlig455_033665 {REF} {Length: 4082} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=199.8]} {Human: ENSG00000110881, ASIC1, acid sensing ion channel subunit 1, [Score=62.0, Expect=2e-09]} {Mouse: ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=56.6, Expect=6e-08]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=68.6, Expect=9e-12]} {Smed: dd_Smed_v6_19599_0_1, dd_Smed_v6_19599_0_1, [RH, Score=483, Expect=8e-165]} {RNA1509_46829} {RNA1310_13649, RNA1509_46829} {RNA1509_46829, RNA815_15065}
94. MligTC455_12607 22 0.46 Mlig455_022861

Neo: -

Age: -

1.826 - 0.968 0.858 - - - Mlig455_022861 {REF} {Length: 614} {TRANSSPLICED} {RNA1310_92283}
95. MligTC455_35365 14 0.29 Mlig455_051974

Neo: -

Age: -

NPFFR2 1.823 - - 0.968 - 0.855 - Mlig455_051974 {REF} {Length: 1412} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=184.8]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=44.6]} {Human: ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=172, Expect=6e-49]} {Mouse: ENSMUSG00000035528, Npffr2, neuropeptide FF receptor 2, [Score=162, Expect=3e-45]; ENSMUSG00000028778, Hcrtr1, hypocretin (orexin) receptor 1, [Score=155, Expect=7e-43]} {Dmel: FBgn0004842, RYa-R, RYamide receptor, [Score=168, Expect=3e-47]} {Celegans: WBGene00022004, npr-22, NeuroPeptide Receptor family, [RH, Score=157, Expect=9e-44]} {Smed: dd_Smed_v6_15625_0_1, dd_Smed_v6_15625_0_1, [Score=265, Expect=5e-85]} {RNA1310_123208} {RNA815_46307}
96. MligTC455_25056 93 1.94 Mlig455_049698, Mlig455_049704

Neo: -

Age: -

Region-enriched R2: 5.783/0.00015

1.822 - - 0.957 - 0.865 -

Mlig455_049698 {REF} {Length: 2094} {Smed: dd_Smed_v6_10049_0_1, dd_Smed_v6_10049_0_1, [Score=104, Expect=1e-23]} {RNA1310_40293} {RNA815_29568}

Mlig455_049704 {REF} {Length: 2512} {RNA1509_20101} {RNA1310_40293} {RNA815_29568}
97. MligTC455_19875 82 1.71 Mlig455_024408

Neo: -

Age: Down-Up-Down

1.821 - - 0.953 - 0.868 - Mlig455_024408 {REF} {Length: 2479} {Pfam: CD20-like family [PF04103.17, score=40.9]} {Mouse: ENSMUSG00000048004, Tmem196, transmembrane protein 196, [Score=63.5, Expect=2e-12]} {Smed: dd_Smed_v6_14043_0_1, dd_Smed_v6_14043_0_1, [Score=184, Expect=5e-59]} {RNA1509_25506} {RNA1310_4968.1} {RNA815_23744}
98. MligTC455_25766 42 0.88 Mlig455_008785, Mlig455_008821, Mlig455_008919

Neo: -

Age: -

Region-enriched R2: 5.588/0.00166

1.821 - 0.862 0.959 - - -

Mlig455_008785 {REF} {Length: 1744} {RNA1310_20437} {RNA815_15201}

Mlig455_008821 {REF} {Length: 2074} {RNA1310_20437} {RNA815_15201}

Mlig455_008919 {REF} {Length: 2074} {RNA1310_20437} {RNA815_15201}
99. MligTC455_53657 221 4.6 Mlig455_039396

Neo: -

Age: -

Region-enriched R2: 6.078/0.00340

1.821 - 0.975 - - 0.846 - Mlig455_039396 {REF} {Length: 1026} {Pfam: emp24/gp25L/p24 family/GOLD [PF01105.26, score=21.0]} {RNA1509_40972} {RNA1310_35649.1, RNA1509_40972} {RNA1509_40972, RNA815_17004}
100. MligTC455_36567 18 0.37 Mlig455_065030

Neo: -

Age: -

1.819 - 0.996 0.823 - - - Mlig455_065030 {REF} {Length: 672}

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